9 recherche sur le mot-clé 'Child Development/physiology'

Negative Controlling Parenting and Child Personality as Modifiers of Psychosocial Development in Youth with Autism Spectrum Disorder: A 9-Year Longitudinal Study at the Level of Within-Person Change / Lana E. DE CLERCQ in Journal of Autism and Developmental Disorders, 51-8 (August 2021)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 51-8 (August 2021) . - p.2891-2907 Titre : Negative Controlling Parenting and Child Personality as Modifiers of Psychosocial Development in Youth with Autism Spectrum Disorder: A 9-Year Longitudinal Study at the Level of Within-Person Change Type de document : texte imprimé Auteurs : Lana E. DE CLERCQ, Auteur ; Lisa M. DIELEMAN, Auteur ; Jolene VAN DER KAAP-DEEDER, Auteur ; Bart SOENENS, Auteur ; Peter PRINZIE, Auteur ; Sarah S.W. DE PAUW, Auteur Article en page(s) : p.2891-2907 Langues : Anglais (eng) Mots-clés : Adolescent  Autism Spectrum Disorder/psychology  Child  Child Development/physiology  Female  Humans  Longitudinal Studies  Male  Parent-Child Relations  Parenting/psychology  Parents/psychology  Personality/physiology  Young Adult  Autism spectrum disorder  Parenting  Personality  Psychosocial functioning  Within-person level Index. décimale : PER Périodiques Résumé : This nine-year longitudinal study addresses the joint contribution of parent-rated negative controlling parenting and child personality on psychosocial outcomes in 141 families of children with autism spectrum disorder (83% boys, mean age Time 1 = 10.1). Latent change modeling revealed substantial variation in within-person change in parenting and psychosocial outcomes across a six- and three-year-interval. Over time, negative controlling parenting and child personality were consistently related to externalizing problems, whereas child personality was differentially related to internalizing problems and psychosocial strengths. Three personality-by-parenting interactions were significant, suggesting that children with less mature personality traits show more externalizing behaviors in the presence of controlling parenting. This study identified both parenting and child personality as important modifiers of developmental outcomes in youth with autism. En ligne : http://dx.doi.org/10.1007/s10803-020-04761-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=453 [article] Negative Controlling Parenting and Child Personality as Modifiers of Psychosocial Development in Youth with Autism Spectrum Disorder: A 9-Year Longitudinal Study at the Level of Within-Person Change [texte imprimé] / Lana E. DE CLERCQ, Auteur ; Lisa M. DIELEMAN, Auteur ; Jolene VAN DER KAAP-DEEDER, Auteur ; Bart SOENENS, Auteur ; Peter PRINZIE, Auteur ; Sarah S.W. DE PAUW, Auteur . - p.2891-2907. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 51-8 (August 2021) . - p.2891-2907 Mots-clés : Adolescent  Autism Spectrum Disorder/psychology  Child  Child Development/physiology  Female  Humans  Longitudinal Studies  Male  Parent-Child Relations  Parenting/psychology  Parents/psychology  Personality/physiology  Young Adult  Autism spectrum disorder  Parenting  Personality  Psychosocial functioning  Within-person level Index. décimale : PER Périodiques Résumé : This nine-year longitudinal study addresses the joint contribution of parent-rated negative controlling parenting and child personality on psychosocial outcomes in 141 families of children with autism spectrum disorder (83% boys, mean age Time 1 = 10.1). Latent change modeling revealed substantial variation in within-person change in parenting and psychosocial outcomes across a six- and three-year-interval. Over time, negative controlling parenting and child personality were consistently related to externalizing problems, whereas child personality was differentially related to internalizing problems and psychosocial strengths. Three personality-by-parenting interactions were significant, suggesting that children with less mature personality traits show more externalizing behaviors in the presence of controlling parenting. This study identified both parenting and child personality as important modifiers of developmental outcomes in youth with autism. En ligne : http://dx.doi.org/10.1007/s10803-020-04761-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=453

Disrupted visual attention relates to cognitive development in infants with Neurofibromatosis Type 1 / Jannath BEGUM-ALI in Journal of Neurodevelopmental Disorders, 17 (2025)  

Public ISBD [article]  inJournal of Neurodevelopmental Disorders > 17 (2025) Titre : Disrupted visual attention relates to cognitive development in infants with Neurofibromatosis Type 1 Type de document : texte imprimé Auteurs : Jannath BEGUM-ALI, Auteur ; Luke MASON, Auteur ; Tony CHARMAN, Auteur ; Mark H. JOHNSON, Auteur ; Jonathan GREEN, Auteur ; Shruti GARG, Auteur ; Emily J.H. JONES, Auteur ; THE STAARS AND EDEN TEAMS, Auteur Langues : Anglais (eng) Mots-clés : Humans  Neurofibromatosis 1/complications/physiopathology  Infant  Attention/physiology  Male  Female  Child Development/physiology  Longitudinal Studies  Visual Perception/physiology  Attention Deficit Disorder with Hyperactivity/physiopathology  Cognition/physiology  Autism Spectrum Disorder/physiopathology  Attention deficit hyperactivity disorder  Autism spectrum disorder  Eye tracking  Longitudinal  Neurofibromatosis Type 1  Visual attention  consent was provided by the parent(s) prior to the commencement of the study. The  testing only took place if the infants were in a content and alert state. Ethical  approval was granted by the National Research Ethics Service and the Research  Ethics Committee of the Department of Psychological Sciences, Birkbeck,  University of London. Consent for publication: Not applicable. Competing  interests: Dr Jannath Begum Ali declares no conflict of interest. Dr Luke Mason  declares no conflict of interest. Professor Tony Charman has served as a paid  consultant to F. Hoffmann-La Roche Ltd and Servier. He has received royalties  from Sage Publications and Guildford Publications. . Dr Shruti Garg declares no  conflict of interest. Professor Jonathan Green declares no conflict of interest.  Professor Mark H. Johnson declares no conflict of interest. Professor Emily J.H.  Jones declares no conflict of interest. The STAARS team declares no conflict of  interest. The EDEN team declares no conflict of interest. Index. décimale : PER Périodiques Résumé : BACKGROUND: Neurofibromatosis Type 1 is a genetic condition diagnosed in infancy that substantially increases the likelihood of a child experiencing cognitive and developmental difficulties, including Autism Spectrum Disorder (ASD) and Attention Deficit Hyperactivity Disorder (ADHD). Children with NF1 show clear differences in attention, but whether these differences emerge in early development and how they relate to broader difficulties with cognitive and learning skills is unclear. To address this question requires longitudinal prospective studies from infancy, where the relation between domains of visual attention (including exogenous and endogenous shifting) and cognitive development can be mapped over time. METHODS: We report data from 28 infants with NF1 tested longitudinally at 5, 10 and 14 months compared to cohorts of 29 typical likelihood infants (with no history of NF1 or ASD and/or ADHD), and 123 infants with a family history of ASD and/or ADHD. We used an eyetracking battery to measure both exogenous and endogenous control of visual attention. RESULTS: Infants with NF1 demonstrated intact social orienting, but slower development of endogenous visual foraging. This slower development presented as prolonged engagement with a salient stimulus in a static display relative to typically developing infants. In terms of exogenous attention shifting, NF1 infants showed faster saccadic reaction times than typical likelihood infants. However, the NF1 group demonstrated a slower developmental improvement from 5 to 14 months of age. Individual differences in foraging and saccade times were concurrently related to visual reception abilities within the full infant cohort (NF1, typical likelihood and those with a family history of ASD/ADHD). CONCLUSIONS: Our results provide preliminary evidence that alterations in saccadic reaction time and visual foraging may contribute to learning difficulties in infants with NF1. En ligne : https://dx.doi.org/10.1186/s11689-025-09599-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=576 [article] Disrupted visual attention relates to cognitive development in infants with Neurofibromatosis Type 1 [texte imprimé] / Jannath BEGUM-ALI, Auteur ; Luke MASON, Auteur ; Tony CHARMAN, Auteur ; Mark H. JOHNSON, Auteur ; Jonathan GREEN, Auteur ; Shruti GARG, Auteur ; Emily J.H. JONES, Auteur ; THE STAARS AND EDEN TEAMS, Auteur. Langues : Anglais (eng) in Journal of Neurodevelopmental Disorders > 17 (2025) Mots-clés : Humans  Neurofibromatosis 1/complications/physiopathology  Infant  Attention/physiology  Male  Female  Child Development/physiology  Longitudinal Studies  Visual Perception/physiology  Attention Deficit Disorder with Hyperactivity/physiopathology  Cognition/physiology  Autism Spectrum Disorder/physiopathology  Attention deficit hyperactivity disorder  Autism spectrum disorder  Eye tracking  Longitudinal  Neurofibromatosis Type 1  Visual attention  consent was provided by the parent(s) prior to the commencement of the study. The  testing only took place if the infants were in a content and alert state. Ethical  approval was granted by the National Research Ethics Service and the Research  Ethics Committee of the Department of Psychological Sciences, Birkbeck,  University of London. Consent for publication: Not applicable. Competing  interests: Dr Jannath Begum Ali declares no conflict of interest. Dr Luke Mason  declares no conflict of interest. Professor Tony Charman has served as a paid  consultant to F. Hoffmann-La Roche Ltd and Servier. He has received royalties  from Sage Publications and Guildford Publications. . Dr Shruti Garg declares no  conflict of interest. Professor Jonathan Green declares no conflict of interest.  Professor Mark H. Johnson declares no conflict of interest. Professor Emily J.H.  Jones declares no conflict of interest. The STAARS team declares no conflict of  interest. The EDEN team declares no conflict of interest. Index. décimale : PER Périodiques Résumé : BACKGROUND: Neurofibromatosis Type 1 is a genetic condition diagnosed in infancy that substantially increases the likelihood of a child experiencing cognitive and developmental difficulties, including Autism Spectrum Disorder (ASD) and Attention Deficit Hyperactivity Disorder (ADHD). Children with NF1 show clear differences in attention, but whether these differences emerge in early development and how they relate to broader difficulties with cognitive and learning skills is unclear. To address this question requires longitudinal prospective studies from infancy, where the relation between domains of visual attention (including exogenous and endogenous shifting) and cognitive development can be mapped over time. METHODS: We report data from 28 infants with NF1 tested longitudinally at 5, 10 and 14 months compared to cohorts of 29 typical likelihood infants (with no history of NF1 or ASD and/or ADHD), and 123 infants with a family history of ASD and/or ADHD. We used an eyetracking battery to measure both exogenous and endogenous control of visual attention. RESULTS: Infants with NF1 demonstrated intact social orienting, but slower development of endogenous visual foraging. This slower development presented as prolonged engagement with a salient stimulus in a static display relative to typically developing infants. In terms of exogenous attention shifting, NF1 infants showed faster saccadic reaction times than typical likelihood infants. However, the NF1 group demonstrated a slower developmental improvement from 5 to 14 months of age. Individual differences in foraging and saccade times were concurrently related to visual reception abilities within the full infant cohort (NF1, typical likelihood and those with a family history of ASD/ADHD). CONCLUSIONS: Our results provide preliminary evidence that alterations in saccadic reaction time and visual foraging may contribute to learning difficulties in infants with NF1. En ligne : https://dx.doi.org/10.1186/s11689-025-09599-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=576

Does a high threshold of sensory responsiveness affect the development of pretend play in children on the autism spectrum? / Karolina KRZYSZTOFIK in Journal of Neurodevelopmental Disorders, 16 (2024)  

Public ISBD [article]  inJournal of Neurodevelopmental Disorders > 16 (2024) Titre : Does a high threshold of sensory responsiveness affect the development of pretend play in children on the autism spectrum? Type de document : texte imprimé Auteurs : Karolina KRZYSZTOFIK, Auteur Langues : Anglais (eng) Mots-clés : Humans  Autism Spectrum Disorder/physiopathology  Male  Female  Child, Preschool  Play and Playthings  Child  Child Development/physiology  Theory of Mind/physiology  Autism spectrum  Level of sensory responsiveness  Pretend play  relationships with other people or organizations within three years of beginning  the submitted work that could inappropriately influence, or be perceived to  influence, their work. The author declares that they have no competing interests. Index. décimale : PER Périodiques Résumé : BACKGROUND: Among the current avenues of research into the origins and development of the autism spectrum, those concerning atypical levels of sensory responsiveness are gaining increasing relevance. Researchers note the relationship of sensory responsiveness in children on the autism spectrum to their motor, cognitive and social development. Current research reports combines the responsiveness to sensory stimuli also with the development of pretend play. Aim of this study was to verify the relationship between the level of development of pretend play and the level of sensory responsiveness in children on the autism spectrum. METHODS: A study was conducted in a group of 63 children with a diagnosis of autism spectrum aged from 3 years and 7 months to 9 years and 3 months using: Pretend Play subscale from the Theory of Mind Mechanism Scale and Sensory Experiences Questionnaire version 2.1. RESULTS: The results revealed that elevated sensory hyporesponsiveness predicted low pretend play skills in the group of participating children. CONCLUSION: The study verified the contribution of the level of sensory hyporesponsiveness to explaining the atypical development of pretend play in children on the autism spectrum. En ligne : https://dx.doi.org/10.1186/s11689-024-09551-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=575 [article] Does a high threshold of sensory responsiveness affect the development of pretend play in children on the autism spectrum? [texte imprimé] / Karolina KRZYSZTOFIK, Auteur. Langues : Anglais (eng) in Journal of Neurodevelopmental Disorders > 16 (2024) Mots-clés : Humans  Autism Spectrum Disorder/physiopathology  Male  Female  Child, Preschool  Play and Playthings  Child  Child Development/physiology  Theory of Mind/physiology  Autism spectrum  Level of sensory responsiveness  Pretend play  relationships with other people or organizations within three years of beginning  the submitted work that could inappropriately influence, or be perceived to  influence, their work. The author declares that they have no competing interests. Index. décimale : PER Périodiques Résumé : BACKGROUND: Among the current avenues of research into the origins and development of the autism spectrum, those concerning atypical levels of sensory responsiveness are gaining increasing relevance. Researchers note the relationship of sensory responsiveness in children on the autism spectrum to their motor, cognitive and social development. Current research reports combines the responsiveness to sensory stimuli also with the development of pretend play. Aim of this study was to verify the relationship between the level of development of pretend play and the level of sensory responsiveness in children on the autism spectrum. METHODS: A study was conducted in a group of 63 children with a diagnosis of autism spectrum aged from 3 years and 7 months to 9 years and 3 months using: Pretend Play subscale from the Theory of Mind Mechanism Scale and Sensory Experiences Questionnaire version 2.1. RESULTS: The results revealed that elevated sensory hyporesponsiveness predicted low pretend play skills in the group of participating children. CONCLUSION: The study verified the contribution of the level of sensory hyporesponsiveness to explaining the atypical development of pretend play in children on the autism spectrum. En ligne : https://dx.doi.org/10.1186/s11689-024-09551-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=575

Mutual Gaze: An Active Ingredient for Social Development in Toddlers with ASD: A Randomized Control Trial / Pamela Rosenthal ROLLINS in Journal of Autism and Developmental Disorders, 51-6 (June 2021)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 51-6 (June 2021) . - p.1921-1938 Titre : Mutual Gaze: An Active Ingredient for Social Development in Toddlers with ASD: A Randomized Control Trial Type de document : texte imprimé Auteurs : Pamela Rosenthal ROLLINS, Auteur ; Adrienne DE FROY, Auteur ; Michelle CAMPBELL, Auteur ; Renee Thibodeau HOFFMAN, Auteur Article en page(s) : p.1921-1938 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/psychology  Child Development/physiology  Child, Preschool  Communication  Early Intervention, Educational/methods  Education, Special/methods  Female  Fixation, Ocular  Humans  Male  Social Interaction  ASD intervention  Autism spectrum disorder  Mutual gaze  Social development  Board’s (THECB) Autism Grant Program and has received speaker honorariums for  several speaking engagements. De Froy’s research assistantship is supported by THECB  Autism Grant (Rollins, PI). Renee Hoffman and Michelle Campbell are owners of  Pathways Early Autism Intervention, LLC and authors of the Pathways Parent Training  Program(®). Pathways Early Autism Intervention, LLC receives compensation from Part  C Early Intervention agencies for training personnel in the implementation of the  Pathways Parent Training Program(®) and for the Parent Training Program(®) Manuals  which are provided to participating families in Part C programs. In addition, they  receive compensation from THECB Autism Grant (Rollins, PI) for consultation and for  Pathways(®) Early Autism Intervention Parent Training Manuals (version 1), provided  to participating families in the study. Index. décimale : PER Périodiques Résumé : We examined the efficacy of an early autism intervention for use in early childhood intervention (ECI) and mutual gaze as a contributor to social development. Seventy-eight families were randomly assigned to one of three 12-week interventions: Pathways (with a mutual gaze component), communication, or services-as-usual (SAU). The Pathways/SAU comparison concerned the efficacy of Pathways for ECI, and the Pathways/communication comparison, mutual gaze. The Pathways group made significantly more change on social measures, communicative synchrony, and adaptive functioning compared with the SAU group and on social measures compared with the communication group. There were no group differences for communicative acts. The results support Pathways as a potential ECI program and mutual gaze as an active ingredient for social and communication development. En ligne : http://dx.doi.org/10.1007/s10803-020-04672-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452 [article] Mutual Gaze: An Active Ingredient for Social Development in Toddlers with ASD: A Randomized Control Trial [texte imprimé] / Pamela Rosenthal ROLLINS, Auteur ; Adrienne DE FROY, Auteur ; Michelle CAMPBELL, Auteur ; Renee Thibodeau HOFFMAN, Auteur . - p.1921-1938. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 51-6 (June 2021) . - p.1921-1938 Mots-clés : Autism Spectrum Disorder/psychology  Child Development/physiology  Child, Preschool  Communication  Early Intervention, Educational/methods  Education, Special/methods  Female  Fixation, Ocular  Humans  Male  Social Interaction  ASD intervention  Autism spectrum disorder  Mutual gaze  Social development  Board’s (THECB) Autism Grant Program and has received speaker honorariums for  several speaking engagements. De Froy’s research assistantship is supported by THECB  Autism Grant (Rollins, PI). Renee Hoffman and Michelle Campbell are owners of  Pathways Early Autism Intervention, LLC and authors of the Pathways Parent Training  Program(®). Pathways Early Autism Intervention, LLC receives compensation from Part  C Early Intervention agencies for training personnel in the implementation of the  Pathways Parent Training Program(®) and for the Parent Training Program(®) Manuals  which are provided to participating families in Part C programs. In addition, they  receive compensation from THECB Autism Grant (Rollins, PI) for consultation and for  Pathways(®) Early Autism Intervention Parent Training Manuals (version 1), provided  to participating families in the study. Index. décimale : PER Périodiques Résumé : We examined the efficacy of an early autism intervention for use in early childhood intervention (ECI) and mutual gaze as a contributor to social development. Seventy-eight families were randomly assigned to one of three 12-week interventions: Pathways (with a mutual gaze component), communication, or services-as-usual (SAU). The Pathways/SAU comparison concerned the efficacy of Pathways for ECI, and the Pathways/communication comparison, mutual gaze. The Pathways group made significantly more change on social measures, communicative synchrony, and adaptive functioning compared with the SAU group and on social measures compared with the communication group. There were no group differences for communicative acts. The results support Pathways as a potential ECI program and mutual gaze as an active ingredient for social and communication development. En ligne : http://dx.doi.org/10.1007/s10803-020-04672-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452

Functional connectivity patterns differ as a function of co-occurring attentional problems in preschoolers with autism / Alex BOXBERGER in Journal of Neurodevelopmental Disorders, 17 (2025)  

Public ISBD [article]  inJournal of Neurodevelopmental Disorders > 17 (2025) Titre : Functional connectivity patterns differ as a function of co-occurring attentional problems in preschoolers with autism Type de document : texte imprimé Auteurs : Alex BOXBERGER, Auteur ; Bosi CHEN, Auteur ; Lindsay OLSON, Auteur ; Michaela CORDOVA, Auteur ; Judy MAHMALJI, Auteur ; Adriana RIOS, Auteur ; Annika C. LINKE, Auteur ; Inna FISHMAN, Auteur Langues : Anglais (eng) Mots-clés : Humans  Child, Preschool  Male  Female  Autism Spectrum Disorder/physiopathology/diagnostic imaging/complications  Attention Deficit Disorder with Hyperactivity/physiopathology/diagnostic  imaging/complications/epidemiology  Magnetic Resonance Imaging  Infant  Connectome  Brain/physiopathology/diagnostic imaging  Nerve Net/physiopathology/diagnostic imaging  Child Development/physiology  Attention  Autism spectrum  Early development  Functional MRI  Network connectivity  was approved by the institutional review boards of the University of California  San Diego and San Diego State University (Joint Review IRB #151091). Informed  consent was obtained from caregivers of all children included in the study.  Consent for publication: Not applicable. Competing interests: The authors declare  no competing interests. Index. décimale : PER Périodiques Résumé : BACKGROUND: Symptoms of attention-deficit/hyperactivity disorder (ADHD) are common in children with autism spectrum disorder (ASD), and are associated with greater developmental challenges, poorer clinical outcomes, and alterations in functional connectivity (FC) of the brain. However, despite the consensus that ASD and other neurodevelopmental conditions emerge early in life, little is known about the trajectories of brain and behavioral development during the first years of life in children with ASD and co-occurring attention problems (AP). METHODS: In a sample of 122 young children (ages 1.5-5 years) with and without ASD, we examined whether toddlers and preschoolers with ASD and co-occurring AP already differ from peers with ASD without co-occurring AP on adaptive and developmental skills, ASD symptoms, and FC of the frontoparietal and salience networks, which have been previously linked to ADHD symptoms in older children with ASD and ADHD. RESULTS: Results of general linear model analyses revealed lower developmental and adaptive skills across multiple domains in children with ASD and elevated AP compared with their peers with lower AP, despite equivalent levels of ASD symptoms. Further, children with ASD and elevated AP showed reduced FC within the frontoparietal network (p = .027), between the frontoparietal and language networks (p = .004), and the frontoparietal and default mode networks (p = .046) in comparison to their peers with lower AP. No group differences in FC of the salience network were observed (all p > .05). CONCLUSIONS: These findings provide evidence that neurodevelopmental and behavioral differences in children with ASD and co-occurring AP emerge very early in life, before a reliable diagnosis of ADHD is typically made. Specifically, these results demonstrate that early inattention symptoms are associated with unique connectivity patterns in executive circuitry as early as the first years of life in toddlers and preschoolers with ASD, likely contributing to the phenotypic and neural heterogeneity recognized in autism. Thus, our results underscore the importance of considering co-occurring conditions early in developmental research and clinical care, as further understanding these trajectories can inform early interventions during the critical time period when they have the greatest potential for positive impact. En ligne : https://dx.doi.org/10.1186/s11689-025-09650-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=576 [article] Functional connectivity patterns differ as a function of co-occurring attentional problems in preschoolers with autism [texte imprimé] / Alex BOXBERGER, Auteur ; Bosi CHEN, Auteur ; Lindsay OLSON, Auteur ; Michaela CORDOVA, Auteur ; Judy MAHMALJI, Auteur ; Adriana RIOS, Auteur ; Annika C. LINKE, Auteur ; Inna FISHMAN, Auteur. Langues : Anglais (eng) in Journal of Neurodevelopmental Disorders > 17 (2025) Mots-clés : Humans  Child, Preschool  Male  Female  Autism Spectrum Disorder/physiopathology/diagnostic imaging/complications  Attention Deficit Disorder with Hyperactivity/physiopathology/diagnostic  imaging/complications/epidemiology  Magnetic Resonance Imaging  Infant  Connectome  Brain/physiopathology/diagnostic imaging  Nerve Net/physiopathology/diagnostic imaging  Child Development/physiology  Attention  Autism spectrum  Early development  Functional MRI  Network connectivity  was approved by the institutional review boards of the University of California  San Diego and San Diego State University (Joint Review IRB #151091). Informed  consent was obtained from caregivers of all children included in the study.  Consent for publication: Not applicable. Competing interests: The authors declare  no competing interests. Index. décimale : PER Périodiques Résumé : BACKGROUND: Symptoms of attention-deficit/hyperactivity disorder (ADHD) are common in children with autism spectrum disorder (ASD), and are associated with greater developmental challenges, poorer clinical outcomes, and alterations in functional connectivity (FC) of the brain. However, despite the consensus that ASD and other neurodevelopmental conditions emerge early in life, little is known about the trajectories of brain and behavioral development during the first years of life in children with ASD and co-occurring attention problems (AP). METHODS: In a sample of 122 young children (ages 1.5-5 years) with and without ASD, we examined whether toddlers and preschoolers with ASD and co-occurring AP already differ from peers with ASD without co-occurring AP on adaptive and developmental skills, ASD symptoms, and FC of the frontoparietal and salience networks, which have been previously linked to ADHD symptoms in older children with ASD and ADHD. RESULTS: Results of general linear model analyses revealed lower developmental and adaptive skills across multiple domains in children with ASD and elevated AP compared with their peers with lower AP, despite equivalent levels of ASD symptoms. Further, children with ASD and elevated AP showed reduced FC within the frontoparietal network (p = .027), between the frontoparietal and language networks (p = .004), and the frontoparietal and default mode networks (p = .046) in comparison to their peers with lower AP. No group differences in FC of the salience network were observed (all p > .05). CONCLUSIONS: These findings provide evidence that neurodevelopmental and behavioral differences in children with ASD and co-occurring AP emerge very early in life, before a reliable diagnosis of ADHD is typically made. Specifically, these results demonstrate that early inattention symptoms are associated with unique connectivity patterns in executive circuitry as early as the first years of life in toddlers and preschoolers with ASD, likely contributing to the phenotypic and neural heterogeneity recognized in autism. Thus, our results underscore the importance of considering co-occurring conditions early in developmental research and clinical care, as further understanding these trajectories can inform early interventions during the critical time period when they have the greatest potential for positive impact. En ligne : https://dx.doi.org/10.1186/s11689-025-09650-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=576

The developmental phenotype of motor delay in extremely preterm infants following early-life respiratory adversity is influenced by brain dysmaturation in the parietal lobe / Wen-Hao YU in Journal of Neurodevelopmental Disorders, 16 (2024)  

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Developmental milestones and cognitive trajectories in school-aged children with 16p11.2 deletion / Jente VERBESSELT in Journal of Neurodevelopmental Disorders, 17 (2025)  

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Developmental milestones and daily living skills in individuals with Angelman syndrome / Anjali SADHWANI in Journal of Neurodevelopmental Disorders, 16 (2024)  

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Early onset and increasing disparities in neurodevelopmental delays from birth to age 6 in children from low socioeconomic backgrounds / Tae Hwan HAN in Journal of Neurodevelopmental Disorders, 16 (2024)  

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