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Faire une suggestionDevelopmental trajectories of conduct problems from childhood to adolescence: Early childhood antecedents and outcomes in adolescence / Olivier F. COLINS in Development and Psychopathology, 37-5 (December 2025)
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Titre : Developmental trajectories of conduct problems from childhood to adolescence: Early childhood antecedents and outcomes in adolescence Type de document : texte imprimé Auteurs : Olivier F. COLINS, Auteur ; Kostas A. FANTI, Auteur ; Karin HELLFELDT, Auteur ; Louise FROGNER, Auteur ; Henrik ANDERSHED, Auteur Article en page(s) : p.2416-2431 Langues : Anglais (eng) Mots-clés : adolescent outcomes antecedents conduct problems cumulative risk developmental trajectories Index. décimale : PER Périodiques Résumé : Children and adolescents display varying trajectories of conduct problems (CP), but it is unclear if these CP trajectories can be distinguished by childhood antecedents and adolescent outcomes. Therefore, we tested if child- and environmental-level risk factors predict CP trajectory membership and if CP trajectories are associated with developmental outcomes in adolescence. Six waves of data (teacher-, parent- and child self-reports) were used from 2,045 children. General growth mixture modeling identified four CP trajectories (waves 2-5): childhood-persistent, childhood-limited, adolescent-onset, and low CP. Relative to the adolescent-onset CP trajectory, wave 1 child- and environmental-level risk factors increased the likelihood of being in the childhood-persistent CP trajectory, though all but two (callous-unemotional traits and non-intact family) antecedents lost significance after controlling for wave 1 conduct problems. Few significant differences emerged in risk factors when comparing childhood-persistent and childhood-limited CP trajectories. Individuals identified in the adolescent-onset and childhood-persistent CP trajectories faced a higher risk for later maladjustment than those in the childhood-limited CP trajectory, whereas the adolescent-onset and childhood-persistent CP trajectories only differed in three out of 13 outcomes. Overall, findings indicate that individuals with CP are at risk for later maladjustment, but predicting the childhood-persistent trajectory of CP in young children is difficult. En ligne : https://dx.doi.org/10.1017/S0954579424001949 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=572
in Development and Psychopathology > 37-5 (December 2025) . - p.2416-2431[article] Developmental trajectories of conduct problems from childhood to adolescence: Early childhood antecedents and outcomes in adolescence [texte imprimé] / Olivier F. COLINS, Auteur ; Kostas A. FANTI, Auteur ; Karin HELLFELDT, Auteur ; Louise FROGNER, Auteur ; Henrik ANDERSHED, Auteur . - p.2416-2431.
Langues : Anglais (eng)
in Development and Psychopathology > 37-5 (December 2025) . - p.2416-2431
Mots-clés : adolescent outcomes antecedents conduct problems cumulative risk developmental trajectories Index. décimale : PER Périodiques Résumé : Children and adolescents display varying trajectories of conduct problems (CP), but it is unclear if these CP trajectories can be distinguished by childhood antecedents and adolescent outcomes. Therefore, we tested if child- and environmental-level risk factors predict CP trajectory membership and if CP trajectories are associated with developmental outcomes in adolescence. Six waves of data (teacher-, parent- and child self-reports) were used from 2,045 children. General growth mixture modeling identified four CP trajectories (waves 2-5): childhood-persistent, childhood-limited, adolescent-onset, and low CP. Relative to the adolescent-onset CP trajectory, wave 1 child- and environmental-level risk factors increased the likelihood of being in the childhood-persistent CP trajectory, though all but two (callous-unemotional traits and non-intact family) antecedents lost significance after controlling for wave 1 conduct problems. Few significant differences emerged in risk factors when comparing childhood-persistent and childhood-limited CP trajectories. Individuals identified in the adolescent-onset and childhood-persistent CP trajectories faced a higher risk for later maladjustment than those in the childhood-limited CP trajectory, whereas the adolescent-onset and childhood-persistent CP trajectories only differed in three out of 13 outcomes. Overall, findings indicate that individuals with CP are at risk for later maladjustment, but predicting the childhood-persistent trajectory of CP in young children is difficult. En ligne : https://dx.doi.org/10.1017/S0954579424001949 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=572 Developmental trajectories of positive and negative affect in children at high and low familial risk for depressive disorder / Thomas M. OLINO in Journal of Child Psychology and Psychiatry, 52-7 (July 2011)
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Titre : Developmental trajectories of positive and negative affect in children at high and low familial risk for depressive disorder Type de document : texte imprimé Auteurs : Thomas M. OLINO, Auteur ; Nestor L. LOPEZ-DURAN, Auteur ; Maria KOVACS, Auteur ; Charles J. GEORGE, Auteur ; Amy L. GENTZLER, Auteur ; Daniel S. SHAW, Auteur Année de publication : 2011 Article en page(s) : p.792-799 Langues : Anglais (eng) Mots-clés : Positive affect negative affect depression risk developmental trajectories Index. décimale : PER Périodiques Résumé : Background: Although low positive affect (PA) and high negative affect (NA) have been posited to predispose to depressive disorders, little is known about the developmental trajectories of these affects in children at familial risk for mood disorders.
Methods: We examined 202 offspring of mothers who had a history of juvenile-onset unipolar depressive disorder (n = 60) or no history of major psychopathology (n = 80). Offspring participated in up to seven annual, structured laboratory tasks that were designed to elicit PA and NA.
Results: Growth curve analyses revealed that PA increased linearly and similarly for all children from late infancy through age 9. However, there also were individual differences in early PA. Relative to control peers, offspring of mothers with lifetime unipolar depression had consistently lower levels of PA, and this association remained significant even when controlling for current maternal depression and maternal affect displays. Growth curve analyses also revealed a significant linear decrease in NA in children across time; however, there was no significant inter-individual variation either in early NA or rate of change in NA.
Conclusion: Attenuated PA (rather than excessive NA) may be an early vulnerability factor for eventual unipolar depressive disorder in at-risk children and may represent one pathway through which depression is transmitted.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2010.02331.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=126
in Journal of Child Psychology and Psychiatry > 52-7 (July 2011) . - p.792-799[article] Developmental trajectories of positive and negative affect in children at high and low familial risk for depressive disorder [texte imprimé] / Thomas M. OLINO, Auteur ; Nestor L. LOPEZ-DURAN, Auteur ; Maria KOVACS, Auteur ; Charles J. GEORGE, Auteur ; Amy L. GENTZLER, Auteur ; Daniel S. SHAW, Auteur . - 2011 . - p.792-799.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 52-7 (July 2011) . - p.792-799
Mots-clés : Positive affect negative affect depression risk developmental trajectories Index. décimale : PER Périodiques Résumé : Background: Although low positive affect (PA) and high negative affect (NA) have been posited to predispose to depressive disorders, little is known about the developmental trajectories of these affects in children at familial risk for mood disorders.
Methods: We examined 202 offspring of mothers who had a history of juvenile-onset unipolar depressive disorder (n = 60) or no history of major psychopathology (n = 80). Offspring participated in up to seven annual, structured laboratory tasks that were designed to elicit PA and NA.
Results: Growth curve analyses revealed that PA increased linearly and similarly for all children from late infancy through age 9. However, there also were individual differences in early PA. Relative to control peers, offspring of mothers with lifetime unipolar depression had consistently lower levels of PA, and this association remained significant even when controlling for current maternal depression and maternal affect displays. Growth curve analyses also revealed a significant linear decrease in NA in children across time; however, there was no significant inter-individual variation either in early NA or rate of change in NA.
Conclusion: Attenuated PA (rather than excessive NA) may be an early vulnerability factor for eventual unipolar depressive disorder in at-risk children and may represent one pathway through which depression is transmitted.En ligne : http://dx.doi.org/10.1111/j.1469-7610.2010.02331.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=126 Brief Report: Developmental Trajectories of Adaptive Behavior in Children and Adolescents with ASD / Allison T. MEYER in Journal of Autism and Developmental Disorders, 48-8 (August 2018)
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Titre : Brief Report: Developmental Trajectories of Adaptive Behavior in Children and Adolescents with ASD Type de document : texte imprimé Auteurs : Allison T. MEYER, Auteur ; Patrick S. POWELL, Auteur ; Nicole BUTERA, Auteur ; Mark R. KLINGER, Auteur ; Laura G. KLINGER, Auteur Article en page(s) : p.2870-2878 Langues : Anglais (eng) Mots-clés : Adaptive behavior Autism Developmental trajectories Index. décimale : PER Périodiques Résumé : Research suggests that individuals with autism spectrum disorder (ASD) have significant difficulties with adaptive behavior skills including daily living and functional communication skills. Few studies have examined the developmental trajectory of adaptive behavior across childhood and adolescence. The present study examined longitudinal trajectories of adaptive behavior in a community-based clinic sample of 186 individuals with ASD. The overall pattern indicated an initial increase in adaptive behavior during early childhood followed by a plateau in skills during adolescence for individuals of all IQ groups. Given the importance of adaptive behavior for employment and quality of life, this study emphasizes the importance of targeting adaptive behavior during adolescence to insure continued gains. En ligne : http://dx.doi.org/10.1007/s10803-018-3538-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=367
in Journal of Autism and Developmental Disorders > 48-8 (August 2018) . - p.2870-2878[article] Brief Report: Developmental Trajectories of Adaptive Behavior in Children and Adolescents with ASD [texte imprimé] / Allison T. MEYER, Auteur ; Patrick S. POWELL, Auteur ; Nicole BUTERA, Auteur ; Mark R. KLINGER, Auteur ; Laura G. KLINGER, Auteur . - p.2870-2878.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 48-8 (August 2018) . - p.2870-2878
Mots-clés : Adaptive behavior Autism Developmental trajectories Index. décimale : PER Périodiques Résumé : Research suggests that individuals with autism spectrum disorder (ASD) have significant difficulties with adaptive behavior skills including daily living and functional communication skills. Few studies have examined the developmental trajectory of adaptive behavior across childhood and adolescence. The present study examined longitudinal trajectories of adaptive behavior in a community-based clinic sample of 186 individuals with ASD. The overall pattern indicated an initial increase in adaptive behavior during early childhood followed by a plateau in skills during adolescence for individuals of all IQ groups. Given the importance of adaptive behavior for employment and quality of life, this study emphasizes the importance of targeting adaptive behavior during adolescence to insure continued gains. En ligne : http://dx.doi.org/10.1007/s10803-018-3538-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=367 Developmental divergence: motor trajectories in children with fragile X syndrome with and without co-occurring autism / Elizabeth A. WILL in Journal of Neurodevelopmental Disorders, 11-1 (December 2019)
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Titre : Developmental divergence: motor trajectories in children with fragile X syndrome with and without co-occurring autism Type de document : texte imprimé Auteurs : Elizabeth A. WILL, Auteur ; Somer L. BISHOP, Auteur ; Jane E. ROBERTS, Auteur Article en page(s) : 23 p. Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Developmental trajectories Fragile X syndrome Motor development Index. décimale : PER Périodiques Résumé : BACKGROUND: Autism spectrum disorder (ASD) is highly prevalent in fragile X syndrome (FXS), affecting 50-70% of males. Motor impairments are a shared feature across autism and FXS that may help to better characterize autism in FXS. As motor skills provide a critical foundation for various language, cognitive, and social outcomes, they may serve an important mechanistic role for autism in FXS. As such, this study aimed to identify differences in motor trajectories across direct assessment and parent-report measures of fine and gross motor development between FXS with and without autism, and typical development, while controlling for cognitive functioning. METHODS: This prospective longitudinal study included 42 children with FXS, 24 of whom also had ASD (FXS + ASD), as well as 40 typically developing children. The Mullen Scales of Early Learning provided a direct measure of fine and gross motor skills, and the Vineland Adaptive Behavior Scales provided a measure of parent-reported fine and gross motor skills. Random slopes and random intercepts multilevel models were tested to determine divergence in developmental motor trajectories between groups when controlling for cognitive level. RESULTS: Model results indicated the children with FXS + ASD diverged from TD children by 9-months on all measures of gross and fine motor skills, even when controlling for cognitive level. Results also indicated an early divergence in motor trajectories of fine and gross motor skills between the FXS + ASD and FXS groups when controlling for cognitive level. This divergence was statistically significant by 18 months, with the FXS + ASD showing decelerated growth in motor skills across direct observation and parent-report measures. CONCLUSIONS: This study is the first to examine longitudinal trends in motor development in children with FXS with and without comorbid ASD using both direct assessment and parent-report measures of fine and gross motor. Furthermore, it is among the first to account for nonverbal cognitive delays, a step towards elucidating the isolated role of motor impairments in FXS with and without ASD. Findings underscore the role of motor impairments as a possible signal representing greater underlying genetic liability, or as a potential catalyst or consequence, of co-occurring autism in FXS. En ligne : https://dx.doi.org/10.1186/s11689-019-9281-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=409
in Journal of Neurodevelopmental Disorders > 11-1 (December 2019) . - 23 p.[article] Developmental divergence: motor trajectories in children with fragile X syndrome with and without co-occurring autism [texte imprimé] / Elizabeth A. WILL, Auteur ; Somer L. BISHOP, Auteur ; Jane E. ROBERTS, Auteur . - 23 p.
Langues : Anglais (eng)
in Journal of Neurodevelopmental Disorders > 11-1 (December 2019) . - 23 p.
Mots-clés : Autism spectrum disorder Developmental trajectories Fragile X syndrome Motor development Index. décimale : PER Périodiques Résumé : BACKGROUND: Autism spectrum disorder (ASD) is highly prevalent in fragile X syndrome (FXS), affecting 50-70% of males. Motor impairments are a shared feature across autism and FXS that may help to better characterize autism in FXS. As motor skills provide a critical foundation for various language, cognitive, and social outcomes, they may serve an important mechanistic role for autism in FXS. As such, this study aimed to identify differences in motor trajectories across direct assessment and parent-report measures of fine and gross motor development between FXS with and without autism, and typical development, while controlling for cognitive functioning. METHODS: This prospective longitudinal study included 42 children with FXS, 24 of whom also had ASD (FXS + ASD), as well as 40 typically developing children. The Mullen Scales of Early Learning provided a direct measure of fine and gross motor skills, and the Vineland Adaptive Behavior Scales provided a measure of parent-reported fine and gross motor skills. Random slopes and random intercepts multilevel models were tested to determine divergence in developmental motor trajectories between groups when controlling for cognitive level. RESULTS: Model results indicated the children with FXS + ASD diverged from TD children by 9-months on all measures of gross and fine motor skills, even when controlling for cognitive level. Results also indicated an early divergence in motor trajectories of fine and gross motor skills between the FXS + ASD and FXS groups when controlling for cognitive level. This divergence was statistically significant by 18 months, with the FXS + ASD showing decelerated growth in motor skills across direct observation and parent-report measures. CONCLUSIONS: This study is the first to examine longitudinal trends in motor development in children with FXS with and without comorbid ASD using both direct assessment and parent-report measures of fine and gross motor. Furthermore, it is among the first to account for nonverbal cognitive delays, a step towards elucidating the isolated role of motor impairments in FXS with and without ASD. Findings underscore the role of motor impairments as a possible signal representing greater underlying genetic liability, or as a potential catalyst or consequence, of co-occurring autism in FXS. En ligne : https://dx.doi.org/10.1186/s11689-019-9281-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=409 Developmental milestones and cognitive trajectories in school-aged children with 16p11.2 deletion / Jente VERBESSELT in Journal of Neurodevelopmental Disorders, 17 (2025)
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Titre : Developmental milestones and cognitive trajectories in school-aged children with 16p11.2 deletion Type de document : texte imprimé Auteurs : Jente VERBESSELT, Auteur ; Jeroen BRECKPOT, Auteur ; Inge ZINK, Auteur ; Ann SWILLEN, Auteur Langues : Anglais (eng) Mots-clés : Humans Child Adolescent Female Male Chromosomes, Human, Pair 16/genetics Child, Preschool Intellectual Disability/physiopathology/genetics Longitudinal Studies Chromosome Deletion Chromosome Disorders/physiopathology/complications/genetics Intelligence Cognition/physiology Child Development/physiology Developmental Disabilities/genetics/physiopathology Fecal Incontinence/physiopathology Intelligence Tests Autistic Disorder 16p11.2 deletion syndrome Cognition Copy number variants Deep phenotyping Developmental trajectories Early development in accordance with the Declaration of Helsinki and approved by the Ethics Committee Research of University Hospitals Leuven (protocol code S54485, 6 December 2012 and 26 March 2021). Patients and their parents were directly informed about the aims of the research project, and all participants signed informed consent. Consent for publication: Not applicable. Competing interests: The authors declare no conflict of interest. Index. décimale : PER Périodiques Résumé : BACKGROUND: 16p11.2 deletion syndrome (16p11.2DS) is a recurrent CNV that occurs de novo in approximately 70% of cases and confers risk for neurodevelopmental disorders, including intellectual disability (ID) and autism spectrum disorders (ASD). The current study focusses on developmental milestones, cognitive profiles and longitudinal cognitive trajectories. METHODS: In-person assessments, digital medical records and parental interviews on developmental history of 24 children (5-16 years) with a confirmed BP4-BP5 16p11.2DS were reviewed and analysed for developmental milestones (motor, language, continence). Standardised intelligence tests were administered in all children, and longitudinal IQ-data were available for a subgroup (79%, 19/24). RESULTS: Motor, language, and continence milestones were delayed. Average IQ was in the borderline range (IQ 71) with 46% (11/24) having borderline IQ (IQ 70-84). Both intra- and interindividual variability were found across the five cognitive domains with significant discrepancies between verbal and non-verbal skills in 55% (11/20). Longitudinal IQ-data indicate that school-aged children with 16p11.2DS perform statistically significantly lower at the second time point (p < 0.001) with 58% showing a growing into deficit trajectory. CONCLUSION: Delayed motor, language and continence milestones are common in 16p11.2DS carriers. School-aged children with 16p11.2DS show increasing cognitive impairments over time, pointing to the need for early diagnosis, regular cognitive follow-up and individualised intervention. The high prevalence of disharmonic IQ-profiles highlights the importance of expanding the focus beyond full-scale IQ (FSIQ) outcomes. Future studies in larger cohorts including carrier relatives are needed to gain more insight into the penetrance and phenotypic variability of 16p11.2DS. En ligne : https://dx.doi.org/10.1186/s11689-025-09615-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=576
in Journal of Neurodevelopmental Disorders > 17 (2025)[article] Developmental milestones and cognitive trajectories in school-aged children with 16p11.2 deletion [texte imprimé] / Jente VERBESSELT, Auteur ; Jeroen BRECKPOT, Auteur ; Inge ZINK, Auteur ; Ann SWILLEN, Auteur.
Langues : Anglais (eng)
in Journal of Neurodevelopmental Disorders > 17 (2025)
Mots-clés : Humans Child Adolescent Female Male Chromosomes, Human, Pair 16/genetics Child, Preschool Intellectual Disability/physiopathology/genetics Longitudinal Studies Chromosome Deletion Chromosome Disorders/physiopathology/complications/genetics Intelligence Cognition/physiology Child Development/physiology Developmental Disabilities/genetics/physiopathology Fecal Incontinence/physiopathology Intelligence Tests Autistic Disorder 16p11.2 deletion syndrome Cognition Copy number variants Deep phenotyping Developmental trajectories Early development in accordance with the Declaration of Helsinki and approved by the Ethics Committee Research of University Hospitals Leuven (protocol code S54485, 6 December 2012 and 26 March 2021). Patients and their parents were directly informed about the aims of the research project, and all participants signed informed consent. Consent for publication: Not applicable. Competing interests: The authors declare no conflict of interest. Index. décimale : PER Périodiques Résumé : BACKGROUND: 16p11.2 deletion syndrome (16p11.2DS) is a recurrent CNV that occurs de novo in approximately 70% of cases and confers risk for neurodevelopmental disorders, including intellectual disability (ID) and autism spectrum disorders (ASD). The current study focusses on developmental milestones, cognitive profiles and longitudinal cognitive trajectories. METHODS: In-person assessments, digital medical records and parental interviews on developmental history of 24 children (5-16 years) with a confirmed BP4-BP5 16p11.2DS were reviewed and analysed for developmental milestones (motor, language, continence). Standardised intelligence tests were administered in all children, and longitudinal IQ-data were available for a subgroup (79%, 19/24). RESULTS: Motor, language, and continence milestones were delayed. Average IQ was in the borderline range (IQ 71) with 46% (11/24) having borderline IQ (IQ 70-84). Both intra- and interindividual variability were found across the five cognitive domains with significant discrepancies between verbal and non-verbal skills in 55% (11/20). Longitudinal IQ-data indicate that school-aged children with 16p11.2DS perform statistically significantly lower at the second time point (p < 0.001) with 58% showing a growing into deficit trajectory. CONCLUSION: Delayed motor, language and continence milestones are common in 16p11.2DS carriers. School-aged children with 16p11.2DS show increasing cognitive impairments over time, pointing to the need for early diagnosis, regular cognitive follow-up and individualised intervention. The high prevalence of disharmonic IQ-profiles highlights the importance of expanding the focus beyond full-scale IQ (FSIQ) outcomes. Future studies in larger cohorts including carrier relatives are needed to gain more insight into the penetrance and phenotypic variability of 16p11.2DS. En ligne : https://dx.doi.org/10.1186/s11689-025-09615-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=576 Deviations from Typical Developmental Trajectories Detectable at 9 Months of Age in Low Risk Children Later Diagnosed with Autism Spectrum Disorder / Michael DAVIDOVITCH in Journal of Autism and Developmental Disorders, 48-8 (August 2018)
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PermalinkNarrowing the gap: Effects of intervention on developmental trajectories in autism / Lars KLINTWALL in Autism, 19-1 (January 2015)
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PermalinkAutism through midlife: trajectories of symptoms, behavioral functioning, and health / Jinkuk HONG in Journal of Neurodevelopmental Disorders, 15 (2023)
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PermalinkDimension-specific symptom patterns in trajectories of broad anxiety: A longitudinal prospective study in school-aged children / Johan AHLEN in Development and Psychopathology, 32-1 (February 2020)
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PermalinkLatent class trajectories of infant temperament and associations with problem behavior at two years of age / Gerald F. GIESBRECHT in Development and Psychopathology, 34-1 (February 2022)
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