Centre d'Information et de documentation du CRA Rhône-Alpes
CRA
Informations pratiques
-
Adresse
Centre d'information et de documentation
du CRA Rhône-Alpes
Centre Hospitalier le Vinatier
bât 211
95, Bd Pinel
69678 Bron CedexHoraires
Lundi au Vendredi
9h00-12h00 13h30-16h00Contact
Tél: +33(0)4 37 91 54 65
Mail
Fax: +33(0)4 37 91 54 37
-
Résultat de la recherche
3 recherche sur le mot-clé 'Sleep/physiology'
Affiner la recherche Générer le flux rss de la recherche
Partager le résultat de cette recherche Faire une suggestion
Evaluation of electroencephalography biomarkers for Angelman syndrome during overnight sleep / Yuval LEVIN in Autism Research, 15-6 (June 2022)
[article]
Titre : Evaluation of electroencephalography biomarkers for Angelman syndrome during overnight sleep Type de document : Texte imprimé et/ou numérique Auteurs : Yuval LEVIN, Auteur ; Nishitha S. HOSAMANE, Auteur ; Taylor E. MCNAIR, Auteur ; Shrujana S. KUNNAM, Auteur ; Benjamin D. PHILPOT, Auteur ; Zheng FAN, Auteur ; Michael S. SIDOROV, Auteur Article en page(s) : p.1031-1042 Langues : Anglais (eng) Mots-clés : Angelman Syndrome/complications/diagnosis/genetics Autism Spectrum Disorder Biomarkers Electroencephalography Humans Retrospective Studies Sleep/physiology Angelman syndrome Eeg biomarker delta sleep spindle Medpace, Inc. for EEG analysis. Index. décimale : PER Périodiques Résumé : Angelman syndrome (AS) is a neurodevelopmental disorder caused by loss-of-function mutations in the maternal copy of the UBE3A gene. AS is characterized by intellectual disability, impaired speech and motor skills, epilepsy, and sleep disruptions. Multiple treatment strategies to re-express functional neuronal UBE3A from the dormant paternal allele were successful in rodent models of AS and have now moved to early phase clinical trials in children. Developing reliable and objective AS biomarkers is essential to guide the design and execution of current and future clinical trials. Our prior work quantified short daytime electroencephalograms (EEGs) to define promising biomarkers for AS. Here, we asked whether overnight sleep is better suited to detect AS EEG biomarkers. We retrospectively analyzed EEGs from 12 overnight sleep studies from individuals with AS with age and sex-matched Down syndrome and neurotypical controls, focusing on low frequency (2-4?Hz) delta rhythms and sleep spindles. Delta EEG rhythms were increased in individuals with AS during all stages of overnight sleep, but overnight sleep did not provide additional benefit over wake in the ability to detect increased delta. Abnormal sleep spindles were not reliably detected in EEGs from individuals with AS during overnight sleep, suggesting that delta rhythms represent a more reliable biomarker. Overall, we conclude that periods of wakefulness are sufficient, and perhaps ideal, to quantify delta EEG rhythms for use as AS biomarkers. LAY SUMMARY: Electroencephalography (EEG) is a safe and reliable way of measuring abnormal brain activity in Angelman syndrome. We found that low-frequency "delta" EEG rhythms are increased in individuals with Angelman syndrome during all stages of overnight sleep. Delta rhythms can be used as a tool to measure improvement in future clinical trials. En ligne : http://dx.doi.org/10.1002/aur.2709 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=476
in Autism Research > 15-6 (June 2022) . - p.1031-1042[article] Evaluation of electroencephalography biomarkers for Angelman syndrome during overnight sleep [Texte imprimé et/ou numérique] / Yuval LEVIN, Auteur ; Nishitha S. HOSAMANE, Auteur ; Taylor E. MCNAIR, Auteur ; Shrujana S. KUNNAM, Auteur ; Benjamin D. PHILPOT, Auteur ; Zheng FAN, Auteur ; Michael S. SIDOROV, Auteur . - p.1031-1042.
Langues : Anglais (eng)
in Autism Research > 15-6 (June 2022) . - p.1031-1042
Mots-clés : Angelman Syndrome/complications/diagnosis/genetics Autism Spectrum Disorder Biomarkers Electroencephalography Humans Retrospective Studies Sleep/physiology Angelman syndrome Eeg biomarker delta sleep spindle Medpace, Inc. for EEG analysis. Index. décimale : PER Périodiques Résumé : Angelman syndrome (AS) is a neurodevelopmental disorder caused by loss-of-function mutations in the maternal copy of the UBE3A gene. AS is characterized by intellectual disability, impaired speech and motor skills, epilepsy, and sleep disruptions. Multiple treatment strategies to re-express functional neuronal UBE3A from the dormant paternal allele were successful in rodent models of AS and have now moved to early phase clinical trials in children. Developing reliable and objective AS biomarkers is essential to guide the design and execution of current and future clinical trials. Our prior work quantified short daytime electroencephalograms (EEGs) to define promising biomarkers for AS. Here, we asked whether overnight sleep is better suited to detect AS EEG biomarkers. We retrospectively analyzed EEGs from 12 overnight sleep studies from individuals with AS with age and sex-matched Down syndrome and neurotypical controls, focusing on low frequency (2-4?Hz) delta rhythms and sleep spindles. Delta EEG rhythms were increased in individuals with AS during all stages of overnight sleep, but overnight sleep did not provide additional benefit over wake in the ability to detect increased delta. Abnormal sleep spindles were not reliably detected in EEGs from individuals with AS during overnight sleep, suggesting that delta rhythms represent a more reliable biomarker. Overall, we conclude that periods of wakefulness are sufficient, and perhaps ideal, to quantify delta EEG rhythms for use as AS biomarkers. LAY SUMMARY: Electroencephalography (EEG) is a safe and reliable way of measuring abnormal brain activity in Angelman syndrome. We found that low-frequency "delta" EEG rhythms are increased in individuals with Angelman syndrome during all stages of overnight sleep. Delta rhythms can be used as a tool to measure improvement in future clinical trials. En ligne : http://dx.doi.org/10.1002/aur.2709 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=476 Sleep patterns, sluggish cognitive tempo, and daytime sleepiness - a commentary on Fredrick et al. (2022) / Dena SADEGHI-BAHMANI in Journal of Child Psychology and Psychiatry, 63-12 (December 2022)
[article]
Titre : Sleep patterns, sluggish cognitive tempo, and daytime sleepiness - a commentary on Fredrick et al. (2022) Type de document : Texte imprimé et/ou numérique Auteurs : Dena SADEGHI-BAHMANI, Auteur ; Serge BRAND, Auteur Article en page(s) : p.1668-1670 Langues : Anglais (eng) Mots-clés : Adolescent Child Humans Attention Deficit Disorder with Hyperactivity/complications Cross-Sectional Studies Sluggish Cognitive Tempo Sleep/physiology Disorders of Excessive Somnolence Cognition/physiology Index. décimale : PER Périodiques Résumé : Fredrick et al. (Journal of Child Psychology and Psychiatry, 2022) showed in their cross-sectional and observational study that higher Sluggish Cognitive Tempo (SCT) traits were associated with more impaired subjective and objective sleep parameters. Importantly, data were gathered from adolescents and their parents, thus, enhancing the validity of the findings. In addition, the observed pattern of associations was unrelated to ADHD traits, age, sex, medication, or pubertal development. In the present commentary, we acknowledge the scientific value and practical and clinical implications of these findings. For future studies, we propose seven research avenues, which might help to further clarify the neurophysiological, psychological, and behavioral associations between SCT traits and sleep patterns. En ligne : http://dx.doi.org/10.1111/jcpp.13693 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490
in Journal of Child Psychology and Psychiatry > 63-12 (December 2022) . - p.1668-1670[article] Sleep patterns, sluggish cognitive tempo, and daytime sleepiness - a commentary on Fredrick et al. (2022) [Texte imprimé et/ou numérique] / Dena SADEGHI-BAHMANI, Auteur ; Serge BRAND, Auteur . - p.1668-1670.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 63-12 (December 2022) . - p.1668-1670
Mots-clés : Adolescent Child Humans Attention Deficit Disorder with Hyperactivity/complications Cross-Sectional Studies Sluggish Cognitive Tempo Sleep/physiology Disorders of Excessive Somnolence Cognition/physiology Index. décimale : PER Périodiques Résumé : Fredrick et al. (Journal of Child Psychology and Psychiatry, 2022) showed in their cross-sectional and observational study that higher Sluggish Cognitive Tempo (SCT) traits were associated with more impaired subjective and objective sleep parameters. Importantly, data were gathered from adolescents and their parents, thus, enhancing the validity of the findings. In addition, the observed pattern of associations was unrelated to ADHD traits, age, sex, medication, or pubertal development. In the present commentary, we acknowledge the scientific value and practical and clinical implications of these findings. For future studies, we propose seven research avenues, which might help to further clarify the neurophysiological, psychological, and behavioral associations between SCT traits and sleep patterns. En ligne : http://dx.doi.org/10.1111/jcpp.13693 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490 What time do you plan to sleep tonight? An intense longitudinal study of adolescent daily sleep self-regulation via planning and its associations with sleep opportunity / Svetlana MASKEVICH in Journal of Child Psychology and Psychiatry, 63-8 (August 2022)
[article]
Titre : What time do you plan to sleep tonight? An intense longitudinal study of adolescent daily sleep self-regulation via planning and its associations with sleep opportunity Type de document : Texte imprimé et/ou numérique Auteurs : Svetlana MASKEVICH, Auteur ; Lin SHEN, Auteur ; Sean P. A. DRUMMOND, Auteur ; Bei BEI, Auteur Article en page(s) : p.900-911 Langues : Anglais (eng) Mots-clés : Actigraphy Adolescent Female Humans Longitudinal Studies Male Schools Self-Control Sleep/physiology Adolescents planning sleep restriction sleep self-regulation teenagers unconstrained sleep Index. décimale : PER Périodiques Résumé : BACKGROUND: Most adolescents are sleep deprived on school days, yet how they self-regulate their sleep-wake behaviours is poorly understood. Using ecological momentary assessment, this intense longitudinal study explored patterns of adolescents' daily bedtime and risetime planning and execution, and whether these behaviours predicted sleep opportunity. METHODS: Every afternoon, for 2 school weeks and the subsequent 2 vacation weeks, 205 (54.1% female, 64.4% non-White) adolescents from year 10 to 12 (MÂ+SD(age) =16.9Â+0.9) reported their plans for bedtime (BT) that evening, and for risetimes (RT) the following day. Actual daily sleep was measured via actigraphy and sleep diary. RESULTS: Some adolescents never planned bedtime (school 19.5%, non-school 53.2%) or risetime (school 1.5%, non-school 24.4%). More adolescents planned consistently (â¥75% of days) on school (BT=29.9%, RT=61.3%) compared to non-school nights (BT=3.5%, RT=2.5%). On average, adolescents went to bed later than planned, with longer delays on non-school (71min) compared to school nights (46min). Of those who executed their plans within 15min, more did it consistently (â¥75% of days) on school (BT=40.9%, RT=67.7%) than on non-school nights/days (BT=29.7%, RT=58.6%). Mixed effects models utilizing daily data, controlling for sex, race, and study day, showed that bedtime planning predicted longer time in bed (TIB; p<.01) on school and shorter TIB on non-school nights (p<.01); and greater delay in actual (compared to planned) BT predicted shorter TIB (p<.001). CONCLUSIONS: Adolescents may require support during the transition from parent-controlled to autonomous sleep self-regulation. Bedtime planning on school nights and going to bed as planned are two modifiable sleep regulatory behaviours that are protective and potential therapeutic targets for increasing sleep opportunity in adolescents. En ligne : http://dx.doi.org/10.1111/jcpp.13540 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486
in Journal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.900-911[article] What time do you plan to sleep tonight? An intense longitudinal study of adolescent daily sleep self-regulation via planning and its associations with sleep opportunity [Texte imprimé et/ou numérique] / Svetlana MASKEVICH, Auteur ; Lin SHEN, Auteur ; Sean P. A. DRUMMOND, Auteur ; Bei BEI, Auteur . - p.900-911.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 63-8 (August 2022) . - p.900-911
Mots-clés : Actigraphy Adolescent Female Humans Longitudinal Studies Male Schools Self-Control Sleep/physiology Adolescents planning sleep restriction sleep self-regulation teenagers unconstrained sleep Index. décimale : PER Périodiques Résumé : BACKGROUND: Most adolescents are sleep deprived on school days, yet how they self-regulate their sleep-wake behaviours is poorly understood. Using ecological momentary assessment, this intense longitudinal study explored patterns of adolescents' daily bedtime and risetime planning and execution, and whether these behaviours predicted sleep opportunity. METHODS: Every afternoon, for 2 school weeks and the subsequent 2 vacation weeks, 205 (54.1% female, 64.4% non-White) adolescents from year 10 to 12 (MÂ+SD(age) =16.9Â+0.9) reported their plans for bedtime (BT) that evening, and for risetimes (RT) the following day. Actual daily sleep was measured via actigraphy and sleep diary. RESULTS: Some adolescents never planned bedtime (school 19.5%, non-school 53.2%) or risetime (school 1.5%, non-school 24.4%). More adolescents planned consistently (â¥75% of days) on school (BT=29.9%, RT=61.3%) compared to non-school nights (BT=3.5%, RT=2.5%). On average, adolescents went to bed later than planned, with longer delays on non-school (71min) compared to school nights (46min). Of those who executed their plans within 15min, more did it consistently (â¥75% of days) on school (BT=40.9%, RT=67.7%) than on non-school nights/days (BT=29.7%, RT=58.6%). Mixed effects models utilizing daily data, controlling for sex, race, and study day, showed that bedtime planning predicted longer time in bed (TIB; p<.01) on school and shorter TIB on non-school nights (p<.01); and greater delay in actual (compared to planned) BT predicted shorter TIB (p<.001). CONCLUSIONS: Adolescents may require support during the transition from parent-controlled to autonomous sleep self-regulation. Bedtime planning on school nights and going to bed as planned are two modifiable sleep regulatory behaviours that are protective and potential therapeutic targets for increasing sleep opportunity in adolescents. En ligne : http://dx.doi.org/10.1111/jcpp.13540 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=486