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Résultat de la recherche
3 recherche sur le mot-clé 'Cognition/physiology'




Bengali translation and characterisation of four cognitive and trait measures for autism spectrum conditions in India / A. RUDRA in Molecular Autism, 7 (2016)
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Titre : Bengali translation and characterisation of four cognitive and trait measures for autism spectrum conditions in India Type de document : Texte imprimé et/ou numérique Auteurs : A. RUDRA, Auteur ; J. R. RAM, Auteur ; T. LOUCAS, Auteur ; Matthew K. BELMONTE, Auteur ; Bhismadev CHAKRABARTI, Auteur Article en page(s) : 50p. Langues : Anglais (eng) Mots-clés : Adolescent Autism Spectrum Disorder/physiopathology/psychology Case-Control Studies Child Cognition/physiology Cross-Cultural Comparison Empathy Facial Expression Female Humans India Intelligence Tests/standards Language Male Regression Analysis Social Skills Surveys and Questionnaires Theory of Mind Translations Assessment Autism Behaviour Bengali Central coherence Perceptual construal Theory of mind Translation Validity Index. décimale : PER Périodiques Résumé : BACKGROUND: Autism is characterised by atypical social-communicative behaviour and restricted range of interests and repetitive behaviours. These features exist in a continuum in the general population. Behavioural measures validated across cultures and languages are required to quantify the dimensional traits of autism in these social and non-social domains. Bengali is the seventh most spoken language in the world. However, there is a serious dearth of data on standard measures of autism-related social and visual cognition in Bengali. METHODS: Bengali translations of two measures related to social-communicative functioning (the Children's Reading the Mind in the Eyes Test (RMET) and a facial emotion recognition test with stimuli taken from the Karolinska Directed Emotional Faces database), one measure of visual perceptual disembedding (the Embedded Figures Test), and a questionnaire measure (the Children's Empathy Quotient) were tested in 25 children with autism spectrum conditions (ASC) and 26 control children (mean age = 10.7 years) in Kolkata, India. Group differences were analysed by t test and multiple regression (after accounting for potential effects of gender, IQ, and age). RESULTS: Behavioural and trait measures were associated with group differences in the expected directions: ASC children scored lower on the Children's Empathy Quotient and the RMET, as well as on facial emotion recognition, but were faster and more accurate on the Embedded Figures Test. Distributional properties of these measures within groups are similar to those reported in Western countries. CONCLUSIONS: These results provide an empirical demonstration of cross-cultural generalisability and applicability of these standard behavioural and trait measures related to autism, in a major world language. En ligne : http://dx.doi.org/10.1186/s13229-016-0111-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=329
in Molecular Autism > 7 (2016) . - 50p.[article] Bengali translation and characterisation of four cognitive and trait measures for autism spectrum conditions in India [Texte imprimé et/ou numérique] / A. RUDRA, Auteur ; J. R. RAM, Auteur ; T. LOUCAS, Auteur ; Matthew K. BELMONTE, Auteur ; Bhismadev CHAKRABARTI, Auteur . - 50p.
Langues : Anglais (eng)
in Molecular Autism > 7 (2016) . - 50p.
Mots-clés : Adolescent Autism Spectrum Disorder/physiopathology/psychology Case-Control Studies Child Cognition/physiology Cross-Cultural Comparison Empathy Facial Expression Female Humans India Intelligence Tests/standards Language Male Regression Analysis Social Skills Surveys and Questionnaires Theory of Mind Translations Assessment Autism Behaviour Bengali Central coherence Perceptual construal Theory of mind Translation Validity Index. décimale : PER Périodiques Résumé : BACKGROUND: Autism is characterised by atypical social-communicative behaviour and restricted range of interests and repetitive behaviours. These features exist in a continuum in the general population. Behavioural measures validated across cultures and languages are required to quantify the dimensional traits of autism in these social and non-social domains. Bengali is the seventh most spoken language in the world. However, there is a serious dearth of data on standard measures of autism-related social and visual cognition in Bengali. METHODS: Bengali translations of two measures related to social-communicative functioning (the Children's Reading the Mind in the Eyes Test (RMET) and a facial emotion recognition test with stimuli taken from the Karolinska Directed Emotional Faces database), one measure of visual perceptual disembedding (the Embedded Figures Test), and a questionnaire measure (the Children's Empathy Quotient) were tested in 25 children with autism spectrum conditions (ASC) and 26 control children (mean age = 10.7 years) in Kolkata, India. Group differences were analysed by t test and multiple regression (after accounting for potential effects of gender, IQ, and age). RESULTS: Behavioural and trait measures were associated with group differences in the expected directions: ASC children scored lower on the Children's Empathy Quotient and the RMET, as well as on facial emotion recognition, but were faster and more accurate on the Embedded Figures Test. Distributional properties of these measures within groups are similar to those reported in Western countries. CONCLUSIONS: These results provide an empirical demonstration of cross-cultural generalisability and applicability of these standard behavioural and trait measures related to autism, in a major world language. En ligne : http://dx.doi.org/10.1186/s13229-016-0111-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=329 Globally elevated excitation-inhibition ratio in children with autism spectrum disorder and below-average intelligence / Viktoriya O. MANYUKHINA in Molecular Autism, 13 (2022)
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Titre : Globally elevated excitation-inhibition ratio in children with autism spectrum disorder and below-average intelligence Type de document : Texte imprimé et/ou numérique Auteurs : Viktoriya O. MANYUKHINA, Auteur ; Andrey O. PROKOFYEV, Auteur ; Ilia A. GALUTA, Auteur ; Dzerassa E. GOIAEVA, Auteur ; Tatiana S. OBUKHOVA, Auteur ; Justin F. SCHNEIDERMAN, Auteur ; Dmitrii I. ALTUKHOV, Auteur ; Tatiana A. STROGANOVA, Auteur ; Elena V. OREKHOVA, Auteur Article en page(s) : 20 p. Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder Child Cognition/physiology Humans Intellectual Disability Intelligence Magnetoencephalography Male 1/f power law Autism spectrum disorders (ASDs) Biomarkers Excitation?inhibition balance Power spectrum Index. décimale : PER Périodiques Résumé : BACKGROUND: Altered neuronal excitation-inhibition (E-I) balance is strongly implicated in ASD. However, it is not known whether the direction and degree of changes in the E-I ratio in individuals with ASD correlates with intellectual disability often associated with this developmental disorder. The spectral slope of the aperiodic 1/f activity reflects the E-I balance at the scale of large neuronal populations and may uncover its putative alternations in individuals with ASD with and without intellectual disability. METHODS: Herein, we used magnetoencephalography (MEG) to test whether the 1/f slope would differentiate ASD children with average and below-average (85) IQ. MEG was recorded at rest with eyes open/closed in 49 boys with ASD aged 6-15 years with IQ ranging from 54 to 128, and in 49 age-matched typically developing (TD) boys. The cortical source activity was estimated using the beamformer approach and individual brain models. We then extracted the 1/f slope by fitting a linear function to the log-log-scale power spectra in the high-frequency range. RESULTS: The global 1/f slope averaged over all cortical sources demonstrated high rank-order stability between the two conditions. Consistent with previous research, it was steeper in the eyes-closed than in the eyes-open condition and flattened with age. Regardless of condition, children with ASD and below-average IQ had flatter slopes than either TD or ASD children with average or above-average IQ. These group differences could not be explained by differences in signal-to-noise ratio or periodic (alpha and beta) activity. LIMITATIONS: Further research is needed to find out whether the observed changes in E-I ratios are characteristic of children with below-average IQ of other diagnostic groups. CONCLUSIONS: The atypically flattened spectral slope of aperiodic activity in children with ASD and below-average IQ suggests a shift of the global E-I balance toward hyper-excitation. The spectral slope can provide an accessible noninvasive biomarker of the E-I ratio for making objective judgments about treatment effectiveness in people with ASD and comorbid intellectual disability. En ligne : http://dx.doi.org/10.1186/s13229-022-00498-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=477
in Molecular Autism > 13 (2022) . - 20 p.[article] Globally elevated excitation-inhibition ratio in children with autism spectrum disorder and below-average intelligence [Texte imprimé et/ou numérique] / Viktoriya O. MANYUKHINA, Auteur ; Andrey O. PROKOFYEV, Auteur ; Ilia A. GALUTA, Auteur ; Dzerassa E. GOIAEVA, Auteur ; Tatiana S. OBUKHOVA, Auteur ; Justin F. SCHNEIDERMAN, Auteur ; Dmitrii I. ALTUKHOV, Auteur ; Tatiana A. STROGANOVA, Auteur ; Elena V. OREKHOVA, Auteur . - 20 p.
Langues : Anglais (eng)
in Molecular Autism > 13 (2022) . - 20 p.
Mots-clés : Autism Spectrum Disorder Child Cognition/physiology Humans Intellectual Disability Intelligence Magnetoencephalography Male 1/f power law Autism spectrum disorders (ASDs) Biomarkers Excitation?inhibition balance Power spectrum Index. décimale : PER Périodiques Résumé : BACKGROUND: Altered neuronal excitation-inhibition (E-I) balance is strongly implicated in ASD. However, it is not known whether the direction and degree of changes in the E-I ratio in individuals with ASD correlates with intellectual disability often associated with this developmental disorder. The spectral slope of the aperiodic 1/f activity reflects the E-I balance at the scale of large neuronal populations and may uncover its putative alternations in individuals with ASD with and without intellectual disability. METHODS: Herein, we used magnetoencephalography (MEG) to test whether the 1/f slope would differentiate ASD children with average and below-average (85) IQ. MEG was recorded at rest with eyes open/closed in 49 boys with ASD aged 6-15 years with IQ ranging from 54 to 128, and in 49 age-matched typically developing (TD) boys. The cortical source activity was estimated using the beamformer approach and individual brain models. We then extracted the 1/f slope by fitting a linear function to the log-log-scale power spectra in the high-frequency range. RESULTS: The global 1/f slope averaged over all cortical sources demonstrated high rank-order stability between the two conditions. Consistent with previous research, it was steeper in the eyes-closed than in the eyes-open condition and flattened with age. Regardless of condition, children with ASD and below-average IQ had flatter slopes than either TD or ASD children with average or above-average IQ. These group differences could not be explained by differences in signal-to-noise ratio or periodic (alpha and beta) activity. LIMITATIONS: Further research is needed to find out whether the observed changes in E-I ratios are characteristic of children with below-average IQ of other diagnostic groups. CONCLUSIONS: The atypically flattened spectral slope of aperiodic activity in children with ASD and below-average IQ suggests a shift of the global E-I balance toward hyper-excitation. The spectral slope can provide an accessible noninvasive biomarker of the E-I ratio for making objective judgments about treatment effectiveness in people with ASD and comorbid intellectual disability. En ligne : http://dx.doi.org/10.1186/s13229-022-00498-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=477 Sleep patterns, sluggish cognitive tempo, and daytime sleepiness - a commentary on Fredrick et al. (2022) / Dena SADEGHI-BAHMANI in Journal of Child Psychology and Psychiatry, 63-12 (December 2022)
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Titre : Sleep patterns, sluggish cognitive tempo, and daytime sleepiness - a commentary on Fredrick et al. (2022) Type de document : Texte imprimé et/ou numérique Auteurs : Dena SADEGHI-BAHMANI, Auteur ; Serge BRAND, Auteur Article en page(s) : p.1668-1670 Langues : Anglais (eng) Mots-clés : Adolescent Child Humans Attention Deficit Disorder with Hyperactivity/complications Cross-Sectional Studies Sluggish Cognitive Tempo Sleep/physiology Disorders of Excessive Somnolence Cognition/physiology Index. décimale : PER Périodiques Résumé : Fredrick et al. (Journal of Child Psychology and Psychiatry, 2022) showed in their cross-sectional and observational study that higher Sluggish Cognitive Tempo (SCT) traits were associated with more impaired subjective and objective sleep parameters. Importantly, data were gathered from adolescents and their parents, thus, enhancing the validity of the findings. In addition, the observed pattern of associations was unrelated to ADHD traits, age, sex, medication, or pubertal development. In the present commentary, we acknowledge the scientific value and practical and clinical implications of these findings. For future studies, we propose seven research avenues, which might help to further clarify the neurophysiological, psychological, and behavioral associations between SCT traits and sleep patterns. En ligne : http://dx.doi.org/10.1111/jcpp.13693 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490
in Journal of Child Psychology and Psychiatry > 63-12 (December 2022) . - p.1668-1670[article] Sleep patterns, sluggish cognitive tempo, and daytime sleepiness - a commentary on Fredrick et al. (2022) [Texte imprimé et/ou numérique] / Dena SADEGHI-BAHMANI, Auteur ; Serge BRAND, Auteur . - p.1668-1670.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 63-12 (December 2022) . - p.1668-1670
Mots-clés : Adolescent Child Humans Attention Deficit Disorder with Hyperactivity/complications Cross-Sectional Studies Sluggish Cognitive Tempo Sleep/physiology Disorders of Excessive Somnolence Cognition/physiology Index. décimale : PER Périodiques Résumé : Fredrick et al. (Journal of Child Psychology and Psychiatry, 2022) showed in their cross-sectional and observational study that higher Sluggish Cognitive Tempo (SCT) traits were associated with more impaired subjective and objective sleep parameters. Importantly, data were gathered from adolescents and their parents, thus, enhancing the validity of the findings. In addition, the observed pattern of associations was unrelated to ADHD traits, age, sex, medication, or pubertal development. In the present commentary, we acknowledge the scientific value and practical and clinical implications of these findings. For future studies, we propose seven research avenues, which might help to further clarify the neurophysiological, psychological, and behavioral associations between SCT traits and sleep patterns. En ligne : http://dx.doi.org/10.1111/jcpp.13693 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490