4 recherche sur le mot-clé 'treatment response'

Neural correlates of explicit and implicit emotion processing in relation to treatment response in pediatric anxiety / Katie L. BURKHOUSE in Journal of Child Psychology and Psychiatry, 58-5 (May 2017)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 58-5 (May 2017) . - p.546-554 Titre : Neural correlates of explicit and implicit emotion processing in relation to treatment response in pediatric anxiety Type de document : Texte imprimé et/ou numérique Auteurs : Katie L. BURKHOUSE, Auteur ; Autumn KUJAWA, Auteur ; Heide KLUMPP, Auteur ; Kate D. FITZGERALD, Auteur ; Christopher S. MONK, Auteur ; K. Luan PHAN, Auteur Article en page(s) : p.546-554 Langues : Anglais (eng) Mots-clés : Pediatric anxiety  treatment response  neuroimaging  attention  emotion processing Index. décimale : PER Périodiques Résumé : Background Approximately 40%–45% of youth with anxiety disorders do not achieve remission (or a substantial reduction in symptoms) following treatment, highlighting the need to identify predictors of treatment response. Given the well-established link between attentional biases and anxiety disorders in youth and adults, this study examined the neural correlates of directing attention toward and away from emotional faces in relation to pediatric anxiety treatment response. Method Prior to beginning treatment with the selective serotonin reuptake inhibitor (SSRI) sertraline or cognitive behavior therapy (CBT), 37 youth (age 7–19 years) with generalized and/or social anxiety disorder completed a task with conditions that manipulated whether participants were instructed to match emotional faces (explicit emotion processing) or match shapes in the context of emotional face distractors (implicit emotion processing) during functional magnetic resonance imaging. Results Results revealed that reduced activation in superior frontal gyrus (SFG), encompassing the dorsal anterior cingulate cortex (ACC) and dorsomedial prefrontal cortex (PFC), during implicit processing of emotional faces predicted a greater reduction in anxiety severity pre-to-post treatment. Post hoc analyses indicated that effects were not significantly moderated by the type of treatment or anxiety type. Conclusions Findings suggest that less recruitment of SFG, including the dorsal ACC and dorsomedial PFC, during implicit emotion processing predicts a greater reduction in youth anxiety symptoms pre-to-post treatment. Youth who exhibit reduced activation in these areas while matching shapes in the context of emotional face distractors may have more to gain from CBT and SSRI treatment due to preexisting deficits in attentional control. These findings suggest that neuroimaging may be a useful tool for predicting which youth are most likely to benefit from anxiety treatment. En ligne : http://dx.doi.org/10.1111/jcpp.12658 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=3060 [article] Neural correlates of explicit and implicit emotion processing in relation to treatment response in pediatric anxiety [Texte imprimé et/ou numérique] / Katie L. BURKHOUSE, Auteur ; Autumn KUJAWA, Auteur ; Heide KLUMPP, Auteur ; Kate D. FITZGERALD, Auteur ; Christopher S. MONK, Auteur ; K. Luan PHAN, Auteur . - p.546-554. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 58-5 (May 2017) . - p.546-554 Mots-clés : Pediatric anxiety  treatment response  neuroimaging  attention  emotion processing Index. décimale : PER Périodiques Résumé : Background Approximately 40%–45% of youth with anxiety disorders do not achieve remission (or a substantial reduction in symptoms) following treatment, highlighting the need to identify predictors of treatment response. Given the well-established link between attentional biases and anxiety disorders in youth and adults, this study examined the neural correlates of directing attention toward and away from emotional faces in relation to pediatric anxiety treatment response. Method Prior to beginning treatment with the selective serotonin reuptake inhibitor (SSRI) sertraline or cognitive behavior therapy (CBT), 37 youth (age 7–19 years) with generalized and/or social anxiety disorder completed a task with conditions that manipulated whether participants were instructed to match emotional faces (explicit emotion processing) or match shapes in the context of emotional face distractors (implicit emotion processing) during functional magnetic resonance imaging. Results Results revealed that reduced activation in superior frontal gyrus (SFG), encompassing the dorsal anterior cingulate cortex (ACC) and dorsomedial prefrontal cortex (PFC), during implicit processing of emotional faces predicted a greater reduction in anxiety severity pre-to-post treatment. Post hoc analyses indicated that effects were not significantly moderated by the type of treatment or anxiety type. Conclusions Findings suggest that less recruitment of SFG, including the dorsal ACC and dorsomedial PFC, during implicit emotion processing predicts a greater reduction in youth anxiety symptoms pre-to-post treatment. Youth who exhibit reduced activation in these areas while matching shapes in the context of emotional face distractors may have more to gain from CBT and SSRI treatment due to preexisting deficits in attentional control. These findings suggest that neuroimaging may be a useful tool for predicting which youth are most likely to benefit from anxiety treatment. En ligne : http://dx.doi.org/10.1111/jcpp.12658 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=3060

Parents’ State and Trait Anxiety: Relationships with Anxiety Severity and Treatment Response in Adolescents with Autism Spectrum Disorders / Caitlin M. CONNER in Journal of Autism and Developmental Disorders, 43-8 (August 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-8 (August 2013) . - p.1811-1818 Titre : Parents’ State and Trait Anxiety: Relationships with Anxiety Severity and Treatment Response in Adolescents with Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Caitlin M. CONNER, Auteur ; Brenna B. MADDOX, Auteur ; Susan W. WHITE, Auteur Article en page(s) : p.1811-1818 Langues : Anglais (eng) Mots-clés : Comorbid anxiety  Parental influences  Treatment response Index. décimale : PER Périodiques Résumé : Comorbid anxiety is common among children with Autism Spectrum Disorder (ASD), and parents of children with ASD are more likely to have anxiety disorders. This study investigated the relationship between parents’ state and trait anxiety and parent-reported internalizing and externalizing symptoms among adolescents (n = 30) with ASD, as well as the relationship of parents’ anxiety symptoms and adolescent treatment response in the context of a randomized controlled trial. Parental state anxiety correlated with severity of adolescent anxiety, and trait anxiety in parents correlated with parent-reported adolescent internalizing and externalizing symptoms. Also, parents of adolescent treatment responders experienced a decrease in their own trait anxiety. Findings highlight the importance of considering parental anxiety when targeting anxiety among youth with ASD. En ligne : http://dx.doi.org/10.1007/s10803-012-1728-0 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2059 [article] Parents’ State and Trait Anxiety: Relationships with Anxiety Severity and Treatment Response in Adolescents with Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Caitlin M. CONNER, Auteur ; Brenna B. MADDOX, Auteur ; Susan W. WHITE, Auteur . - p.1811-1818. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-8 (August 2013) . - p.1811-1818 Mots-clés : Comorbid anxiety  Parental influences  Treatment response Index. décimale : PER Périodiques Résumé : Comorbid anxiety is common among children with Autism Spectrum Disorder (ASD), and parents of children with ASD are more likely to have anxiety disorders. This study investigated the relationship between parents’ state and trait anxiety and parent-reported internalizing and externalizing symptoms among adolescents (n = 30) with ASD, as well as the relationship of parents’ anxiety symptoms and adolescent treatment response in the context of a randomized controlled trial. Parental state anxiety correlated with severity of adolescent anxiety, and trait anxiety in parents correlated with parent-reported adolescent internalizing and externalizing symptoms. Also, parents of adolescent treatment responders experienced a decrease in their own trait anxiety. Findings highlight the importance of considering parental anxiety when targeting anxiety among youth with ASD. En ligne : http://dx.doi.org/10.1007/s10803-012-1728-0 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=2059

Predictors and moderators of recurring self-harm in adolescents participating in a comparative treatment trial of psychological interventions / Molly ADRIAN in Journal of Child Psychology and Psychiatry, 60-10 (October 2019)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 60-10 (October 2019) . - p.1123-1132 Titre : Predictors and moderators of recurring self-harm in adolescents participating in a comparative treatment trial of psychological interventions Type de document : Texte imprimé et/ou numérique Auteurs : Molly ADRIAN, Auteur ; E. MCCAULEY, Auteur ; Michele S. BERK, Auteur ; J. R. ASARNOW, Auteur ; K. KORSLUND, Auteur ; C. AVINA, Auteur ; R. GALLOP, Auteur ; Marsha M. LINEHAN, Auteur Article en page(s) : p.1123-1132 Langues : Anglais (eng) Mots-clés : Moderators  dialectical behavior therapy  predictors  treatment response Index. décimale : PER Périodiques Résumé : BACKGROUND: In primary analyses, dialectical behavior therapy (DBT) was associated with greater reduction in self-harm during treatment than individual/group supportive therapy (IGST). The objective of this paper was to examine predictors and moderators of treatment outcomes for suicidal adolescents who participated in a randomized controlled trial evaluating DBT and IGST. METHODS: Adolescents (N = 173) were included in the intent-to-treat sample and randomized to receive 6 months of DBT or IGST. Potential baseline predictors and moderators were identified within four categories: demographics, severity markers, parental psychopathology, and psychosocial variables. Primary outcomes were suicide attempts (SA) and nonsuicidal self-injury evaluated at baseline, midtreatment (3 months), and end of treatment (6 months) via the Suicide Attempt and Self-Injury Interview (Psychological Assessment, 18, 2006, 303). For each moderator or predictor, a generalized linear mixed model was conducted to examine main and interactive effects of treatment and the candidate variable on outcomes. RESULTS: Adolescents with higher family conflict, more extensive self-harm histories, and more externalizing problems produced on average more reduction on SH frequency from baseline to post-treatment. Adolescents meeting BPD diagnosis were more likely to have high SH frequency at post-treatment. Analyses indicated significant moderation effects for emotion dysregulation on NSSI and SH. DBT was associated with better rates of improvement compared to IGST for adolescents with higher baseline emotion dysregulation and those whose parents reported greater psychopathology and emotion dysregulation. A significant moderation effect for ethnicity on SA over the treatment period was observed, where DBT produced better rate of improvement compared to IGST for Hispanic/Latino individuals. CONCLUSIONS: These findings may help to inform salient treatment targets and guide treatment planning. Adolescents that have high levels of family conflict, externalizing problems, and increased level of severity markers demonstrated the most change in self-harm behaviors over the course of treatment and benefitted from both treatment interventions. Those with higher levels of emotion dysregulation and parent psychopathology may benefit more from the DBT. En ligne : http://dx.doi.org/10.1111/jcpp.13099 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=4067 [article] Predictors and moderators of recurring self-harm in adolescents participating in a comparative treatment trial of psychological interventions [Texte imprimé et/ou numérique] / Molly ADRIAN, Auteur ; E. MCCAULEY, Auteur ; Michele S. BERK, Auteur ; J. R. ASARNOW, Auteur ; K. KORSLUND, Auteur ; C. AVINA, Auteur ; R. GALLOP, Auteur ; Marsha M. LINEHAN, Auteur . - p.1123-1132. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 60-10 (October 2019) . - p.1123-1132 Mots-clés : Moderators  dialectical behavior therapy  predictors  treatment response Index. décimale : PER Périodiques Résumé : BACKGROUND: In primary analyses, dialectical behavior therapy (DBT) was associated with greater reduction in self-harm during treatment than individual/group supportive therapy (IGST). The objective of this paper was to examine predictors and moderators of treatment outcomes for suicidal adolescents who participated in a randomized controlled trial evaluating DBT and IGST. METHODS: Adolescents (N = 173) were included in the intent-to-treat sample and randomized to receive 6 months of DBT or IGST. Potential baseline predictors and moderators were identified within four categories: demographics, severity markers, parental psychopathology, and psychosocial variables. Primary outcomes were suicide attempts (SA) and nonsuicidal self-injury evaluated at baseline, midtreatment (3 months), and end of treatment (6 months) via the Suicide Attempt and Self-Injury Interview (Psychological Assessment, 18, 2006, 303). For each moderator or predictor, a generalized linear mixed model was conducted to examine main and interactive effects of treatment and the candidate variable on outcomes. RESULTS: Adolescents with higher family conflict, more extensive self-harm histories, and more externalizing problems produced on average more reduction on SH frequency from baseline to post-treatment. Adolescents meeting BPD diagnosis were more likely to have high SH frequency at post-treatment. Analyses indicated significant moderation effects for emotion dysregulation on NSSI and SH. DBT was associated with better rates of improvement compared to IGST for adolescents with higher baseline emotion dysregulation and those whose parents reported greater psychopathology and emotion dysregulation. A significant moderation effect for ethnicity on SA over the treatment period was observed, where DBT produced better rate of improvement compared to IGST for Hispanic/Latino individuals. CONCLUSIONS: These findings may help to inform salient treatment targets and guide treatment planning. Adolescents that have high levels of family conflict, externalizing problems, and increased level of severity markers demonstrated the most change in self-harm behaviors over the course of treatment and benefitted from both treatment interventions. Those with higher levels of emotion dysregulation and parent psychopathology may benefit more from the DBT. En ligne : http://dx.doi.org/10.1111/jcpp.13099 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=4067

Clinical and parental predictors of emotion regulation following cognitive behaviour therapy in children with autism / Diana J. TAJIK-PARVINCHI in Autism, 24-4 (May 2020)  

Public ISBD [article]  inAutism > 24-4 (May 2020) . - p.851-866 Titre : Clinical and parental predictors of emotion regulation following cognitive behaviour therapy in children with autism Type de document : Texte imprimé et/ou numérique Auteurs : Diana J. TAJIK-PARVINCHI, Auteur ; Linda FARMUS, Auteur ; Robert CRIBBIE, Auteur ; Carly ALBAUM, Auteur ; Jonathan A WEISS, Auteur Article en page(s) : p.851-866 Langues : Anglais (eng) Mots-clés : autism  cognitive behaviour therapy  efficacy  emotion regulation  treatment response Index. décimale : PER Périodiques Résumé : Children with autism commonly experience difficulty controlling their emotions. Although existing treatments are successful in teaching critical emotion regulation skills, not all children improve. It is important to identify the factors that influence treatment response to be able to reach more children. This study aimed to identify child and parent characteristics that predict treatment response in a 10-week cognitive behaviour therapy treatment for children with autism, 8-12?years of age, and their parents. We found that youth who started the treatment with higher verbal abilities, who were more anxious in social situations, and had parents who were more anxious, were more likely to improve in learning new emotion regulation skills. We also found that children who had more physical discomforts or complaints before starting the treatment were less likely to improve in their negative expressions of emotion. Our study suggests that it is important for clinicians to promote active involvement and learning by avoiding complex language and to use more visual materials to supplement the learning process, and make sure that sessions are sensitive to the individual needs of participants. En ligne : http://dx.doi.org/10.1177/1362361320909178 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=4259 [article] Clinical and parental predictors of emotion regulation following cognitive behaviour therapy in children with autism [Texte imprimé et/ou numérique] / Diana J. TAJIK-PARVINCHI, Auteur ; Linda FARMUS, Auteur ; Robert CRIBBIE, Auteur ; Carly ALBAUM, Auteur ; Jonathan A WEISS, Auteur . - p.851-866. Langues : Anglais (eng) in Autism > 24-4 (May 2020) . - p.851-866 Mots-clés : autism  cognitive behaviour therapy  efficacy  emotion regulation  treatment response Index. décimale : PER Périodiques Résumé : Children with autism commonly experience difficulty controlling their emotions. Although existing treatments are successful in teaching critical emotion regulation skills, not all children improve. It is important to identify the factors that influence treatment response to be able to reach more children. This study aimed to identify child and parent characteristics that predict treatment response in a 10-week cognitive behaviour therapy treatment for children with autism, 8-12?years of age, and their parents. We found that youth who started the treatment with higher verbal abilities, who were more anxious in social situations, and had parents who were more anxious, were more likely to improve in learning new emotion regulation skills. We also found that children who had more physical discomforts or complaints before starting the treatment were less likely to improve in their negative expressions of emotion. Our study suggests that it is important for clinicians to promote active involvement and learning by avoiding complex language and to use more visual materials to supplement the learning process, and make sure that sessions are sensitive to the individual needs of participants. En ligne : http://dx.doi.org/10.1177/1362361320909178 Permalink : http://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=4259