1. Hoffman GE, Le WW, Entezam A, Otsuka N, Tong ZB, Nelson L, Flaws JA, McDonald JH, Jafar S, Usdin K. {{Ovarian Abnormalities in a Mouse Model of Fragile X Primary Ovarian Insufficiency}}. {J Histochem Cytochem};2012 (Apr 2)
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2. Treasure J. {{Coherence and other autistic spectrum traits and eating disorders: Building from mechanism to treatment. The Birgit Olsson lecture}}. {Nord J Psychiatry};2012 (Apr 2)
Treasure J. Coherence and other autistic spectrum traits and eating disorders: Building from mechanism to treatment. The Birgit Olsson lecture. Nord J Psychiatry 2012; Early Online:1-5. Aim: To revisit Gillberg’s hypothesis proposed in 1992, which was that anorexia nervosa should be considered within the spectrum of autistic disorders. Method: A search was made of the literature relating to the behavioural traits, and cognitive, emotional and neuroanatomical intermediate phenotypes that are shared between autistic spectrum disorders (ASD) and anorexia nervosa. Results: People with eating disorders in the acute phase (less so after recovery) share some behavioural traits (social impairment and restricted and repetitive behaviours) and intermediate phenotypes (weak central coherence, and impaired set shifting and theory of mind) with people in the autistic spectrum. Conclusion: Behavioural and intermediate neuropsychological traits are shared between eating disorders and ASD. In part, these are familial but also they are accentuated by the illness state and may be secondary to starvation. These traits have implications for prognosis and treatment.
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3. Waligorska A, Pisula E, Waligorski M, Letachowicz M. {{The AutismPro system in supporting treatment of children with autism in Poland}}. {Pediatr Int};2012 (Apr 2)
Background: The efficacy of early intervention programs for children with autism has been emphasized in many studies. However, access people with autism to professional services in Poland is very limited and the burden of supporting child’s development often falls on parents, especially in families with low socio-economical status and families living far away from big cities. Using the Internet resources in planning and delivering individualized intervention may be useful. The study examined the effects of a home program of intervention based on the AutismPro system with elements of consultative therapy. Methods: Ten families of children with a diagnosis of autism participated in the project; 9 of them completed the 6 month program of intervention. Parents were taught to use the AutismPro system and implement the intervention techniques in a home setting. Modification of the intervention program to suit individual children’s needs and evaluations of children’s progress were performed during consultation meetings with therapists. The pre- and posttreatment measurement of child development was performed using the Psychoeducational Profile-Revised (PEP-R). Results: Children involved in the study progressed in total PEP-R scores and on the PEP-R subtest of fine motor, gross motor, nonverbal and verbal cognitive skills and eye-hand integration. Parents expressed positive opinions on the program. Conclusions: The results suggest that an intervention which combines the use of the Internet support tool and professional consultations may provide benefits to the children with autism. There are however methodological limitations of the study to be taken into account, when interpreting the results. (c) 2012 The Authors. Pediatrics International (c) 2012 Japan Pediatric Society.
