Pubmed du 11/11/12

Pubmed du jour

2012-11-11 12:03:50

1. Kite DM, Gullifer J, Tyson GA. {{Views on the Diagnostic Labels of Autism and Asperger’s Disorder and the Proposed Changes in the DSM}}. {J Autism Dev Disord}. 2012 Nov 11.

With the approaching release of the DSM V in 2013, there has been much debate about the proposal to remove the diagnostic label of Asperger’s disorder from the new DSM. This study explored how health and education professionals perceive the conditions of autism and Asperger’s disorder and their views on the proposed diagnostic changes. Analysis of the 547 participant responses confirmed an increase stigma is associated with the label of autism, with autism considered to be a more severe than the condition of Asperger’s disorder. Approximately half of the participants reported being opposed to proposed diagnostic changes and of the remaining participants, 22 % supported the proposed changes and 28 % expressed uncertainty.

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2. Roberts JE, Long AC, McCary LM, Quady AN, Rose BS, Widrick D, Baranek G. {{Cardiovascular and Behavioral Response to Auditory Stimuli in Boys With Fragile X Syndrome}}. {Journal of pediatric psychology}. 2012 Nov 11.

OBJECTIVE: The aim of this study was to determine whether young boys with fragile X syndrome (FXS) exhibit abnormal physiological or behavioral responses to a moderately intense auditory stimulus, as heightened sensory reactivity is believed to contribute to problem behaviors in this population. METHODS: We examined the physiological basis, via heart activity, of auditory startle in young boys with FXS (n = 22) compared with typically developing controls (n = 27). Associations with mental age, behavioral reactivity, and chronological age were examined. RESULTS: Results suggest that older boys with FXS display increased cardiac reactivity to auditory input than younger boys with FXS that distinguishes them from typically developing controls. Higher mental age was associated with decreased latency to react. CONCLUSIONS: Results contribute to increased understanding of the pathology in sensory processing in boys with FXS, which can inform refinement of the phenotype in young children with FXS and aid in the development of efficacious psychopharmacological and/or behavioral interventions.

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