Pubmed du 12/02/16

Pubmed du jour

2016-02-12 12:03:50

1. Bacanli A. {{Aripiprazole Use in Children Diagnosed with Down Syndrome and Comorbid Autism Spectrum Disorders}}. {J Child Adolesc Psychopharmacol};2016 (Feb 12)

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2. Carrigan N, Allez K. {{Cognitive Behaviour Therapy for Post-Traumatic Stress Disorder in a person with an Autism Spectrum Condition and Intellectual Disability: A Case Study}}. {J Appl Res Intellect Disabil};2016 (Feb 12)
BACKGROUND: One of the difficulties in assessing and treating PTSD in people with intellectual disability is that it may not present with the typical symptoms associated with the disorder. This may be why there is a dearth of literature on the treatment of PTSD using cognitive behavioural approaches for people with intellectual disability (e.g. Ehlers et al. Behav Res Ther, 43, 2005, 413-431). This paper reports the treatment for PTSD in a young man diagnosed with autism and a mild intellectual disability. METHOD: Treatment involved 12 sessions of cognitive therapy for PTSD using the approach developed by Ehlers et al. RESULTS: There was an overall reduction in symptoms and a self-reported elevation in mood. With careful questioning, adaptation of language and elucidation of concepts, the patient was able to fully engage in therapy. DISCUSSION: This case suggests that cognitive approaches to treating PTSD can be successful in people with intellectual disability and autism.

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3. Hens K, Peeters H, Dierickx K. {{The ethics of complexity. Genetics and autism, a literature review}}. {Am J Med Genet B Neuropsychiatr Genet};2016 (Feb 12)
It is commonly believed that the etiology of autism is at least partly explained through genetics. Given the complexity of autism and the variability of the autistic phenotype, genetic research and counseling in this field are also complex and associated with specific ethical questions. Although the ethics of autism genetics, especially with regard to reproductive choices, has been widely discussed on the public fora, an in depth philosophical or bioethical reflection on all aspects of the theme seems to be missing. With this literature review we wanted to map the basic questions and answers that exist in the bioethical literature on autism genetics, research, counseling and reproduction, and provide suggestions as to how the discussion can proceed. We found 19 papers that fitted the description of « bioethics literature focusing on autism genetics, » and analyzed their content to distill arguments and themes. We concluded that because of the complexity of autism, and the uncertainty with regard to its status, more ethical reflection is needed before definite conclusions and recommendations can be drawn. Moreover, there is a dearth of bioethical empirical studies querying the opinions of all parties, including people with autism themselves. Such empirical bioethical studies should be urgently done before bioethical conclusions regarding the aims and desirability of research into autism genes can be done. Also, fundamental philosophical reflection on concepts of disease should accompany research into the etiology of autism. (c) 2016 Wiley Periodicals, Inc.

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4. Hodgson AR, Freeston MH, Honey E, Rodgers J. {{Facing the Unknown: Intolerance of Uncertainty in Children with Autism Spectrum Disorder}}. {J Appl Res Intellect Disabil};2016 (Feb 12)
BACKGROUND: Anxiety is a common problem for children with autism spectrum disorder (ASD). Recent research indicates that intolerance of uncertainty (IU) may be an important aspect of anxiety for this population. IU is the belief that uncertainty is upsetting, and not knowing what is going to happen is negative. There is little known about the phenomenology of IU in children with ASD. We therefore present data from parent focus groups exploring this concept in children with ASD. METHODS: Participants were asked to differentiate IU from dislike of change and fear, and to discuss examples of IU and the strategies they use to manage it. Their experiences of IU and strategies are presented. RESULTS: IU was evident across novel and familiar situations and parents used a variety of strategies to manage IU. Their experiences of IU and strategies used are presented. CONCLUSIONS: Participants were able to identify and provide examples of IU suggesting that it is a recognizable construct among children with ASD.

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5. Momen S. {{Special care dentistry: Treating autistic children}}. {Br Dent J};2016 (Feb 12);220(3):89.

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