Pubmed du 23/11/15

Pubmed du jour

2015-11-23 12:03:50

1. Costanzo F, Menghini D, Casula L, Amendola A, Mazzone L, Valeri G, Vicari S. {{Transcranial Direct Current Stimulation Treatment in an Adolescent with Autism and Drug-Resistant Catatonia}}. {Brain Stimul};2015 (Nov-Dec);8(6):1233-1235.

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2. Foley KR, Trollor J. {{Management of mental ill health in people with autism spectrum disorder}}. {Aust Fam Physician};2015;44(11):784-790.

BACKGROUND: Adults with autism spectrum disorder (ASD) may require medical assessment and care, especially for mental health conditions. Although substantial knowledge and resources are available regarding the management of mental ill health in children with ASD, substantial gaps remain for adults with ASD. Diagnostic overshadowing, limitations of communication skills and the heterogeneous nature of this patient population can make practice in this area more challenging, and can contribute to poorer outcomes, including overprescribing of psychotropic medications. OBJECTIVE: This article aims to describe mental ill health and identify specific considerations for GPs during the assessment and management of adults with ASD. DISCUSSION: The incorporation of specific knowledge and adaptations in the areas of communication, awareness of physical health comorbidities, management of challenging behaviour, impact of the environment, role of carers and an approach that values neurodiversity has the potential to positively influence mental health outcomes of adults with ASD.

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3. Ma NS, Thompson C, Weston S. {{Brief Report: Scurvy as a Manifestation of Food Selectivity in Children with Autism}}. {J Autism Dev Disord};2015 (Nov 21)
Scurvy was diagnosed in seven children at Boston Children’s Hospital. All of the children had a developmental disorder and autism was the most common. They had a long-standing history of food selectivity with diets devoid of fruits and vegetables, and none of the children were supplemented with a multivitamin. They presented with limp, and an elaborate panel of tests and procedures were undertaken before the diagnosis of scurvy was made. Treatment with vitamin C led to rapid recovery of symptoms. This report emphasizes the importance of considering nutritional causes of musculoskeletal symptoms in children with autism and restrictive diets.

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4. Sasson NJ, Shasteen JR, Pinkham AE. {{Brief Report: Reduced Prioritization of Facial Threat in Adults with Autism}}. {J Autism Dev Disord};2015 (Nov 21)
Typically-developing (TD) adults detect angry faces more efficiently within a crowd than non-threatening faces. Prior studies of this social threat superiority effect (TSE) in ASD using tasks consisting of schematic faces and homogeneous crowds have produced mixed results. Here, we employ a more ecologically-valid test of the social TSE and find evidence of a reduced social TSE in adults with ASD (n = 21) relative to TD controls (n = 28). Unlike TD participants, the ASD group failed to show the normative advantage for detecting angry faces faster than happy faces, either within crowds of neutral or emotional faces. These findings parallel prior work indicating a reduced sensitivity in ASD to facial cues of untrustworthiness, and may reflect a vulnerability for evaluating social harm.

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