Genetic covariance between psychopathic traits and anticipatory skin conductance responses to threat: Evidence for a potential endophenotype / Pan WANG in Development and Psychopathology, 27-4 (Part 1) (November 2015)  

Public ISBD [article]  inDevelopment and Psychopathology > 27-4 (Part 1) (November 2015) . - p.1313-1322 Titre : Genetic covariance between psychopathic traits and anticipatory skin conductance responses to threat: Evidence for a potential endophenotype Type de document : Texte imprimé et/ou numérique Auteurs : Pan WANG, Auteur ; Yu GAO, Auteur ; Joshua ISEN, Auteur ; Catherine TUVBLAD, Auteur ; Adrian RAINE, Auteur ; Laura A. BAKER, Auteur Année de publication : 2015 Article en page(s) : p.1313-1322 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The genetic architecture of the association between psychopathic traits and reduced skin conductance responses (SCRs) is poorly understood. By using 752 twins aged 9–10 years, this study investigated the heritability of two SCR measures (anticipatory SCRs to impending aversive stimuli and unconditioned SCRs to the aversive stimuli themselves) in a countdown task. The study also investigated the genetic and environmental sources of the covariance between these SCR measures and two psychopathic personality traits: impulsive/disinhibited (reflecting impulsive–antisocial tendencies) and manipulative/deceitful (reflecting the affective–interpersonal features). For anticipatory SCRs, 27%, 14%, and 59% of the variation was due to genetic, shared environmental, and nonshared environmental effects, respectively, while the percentages for unconditioned SCRs were 44%, 2%, and 54%. The manipulative/deceitful (not impulsive/disinhibited) traits were negatively associated with both anticipatory SCRs (r = –.14, p < .05) and unconditioned SCRs (r = –.17, p < .05) in males only, with the former association significantly accounted for by genetic influences (rg = –.72). Reduced anticipatory SCRs represent a candidate endophenotype for the affective–interpersonal facets of psychopathic traits in males. En ligne : http://dx.doi.org/10.1017/S0954579414001424 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=268 [article] Genetic covariance between psychopathic traits and anticipatory skin conductance responses to threat: Evidence for a potential endophenotype [Texte imprimé et/ou numérique] / Pan WANG, Auteur ; Yu GAO, Auteur ; Joshua ISEN, Auteur ; Catherine TUVBLAD, Auteur ; Adrian RAINE, Auteur ; Laura A. BAKER, Auteur . - 2015 . - p.1313-1322. Langues : Anglais (eng) in Development and Psychopathology > 27-4 (Part 1) (November 2015) . - p.1313-1322 Index. décimale : PER Périodiques Résumé : The genetic architecture of the association between psychopathic traits and reduced skin conductance responses (SCRs) is poorly understood. By using 752 twins aged 9–10 years, this study investigated the heritability of two SCR measures (anticipatory SCRs to impending aversive stimuli and unconditioned SCRs to the aversive stimuli themselves) in a countdown task. The study also investigated the genetic and environmental sources of the covariance between these SCR measures and two psychopathic personality traits: impulsive/disinhibited (reflecting impulsive–antisocial tendencies) and manipulative/deceitful (reflecting the affective–interpersonal features). For anticipatory SCRs, 27%, 14%, and 59% of the variation was due to genetic, shared environmental, and nonshared environmental effects, respectively, while the percentages for unconditioned SCRs were 44%, 2%, and 54%. The manipulative/deceitful (not impulsive/disinhibited) traits were negatively associated with both anticipatory SCRs (r = –.14, p < .05) and unconditioned SCRs (r = –.17, p < .05) in males only, with the former association significantly accounted for by genetic influences (rg = –.72). Reduced anticipatory SCRs represent a candidate endophenotype for the affective–interpersonal facets of psychopathic traits in males. En ligne : http://dx.doi.org/10.1017/S0954579414001424 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=268

Heritability for adolescent antisocial behavior differs with socioeconomic status: gene–environment interaction / Catherine TUVBLAD in Journal of Child Psychology and Psychiatry, 47-7 (July 2006)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 47-7 (July 2006) . - p.734–743 Titre : Heritability for adolescent antisocial behavior differs with socioeconomic status: gene–environment interaction Type de document : Texte imprimé et/ou numérique Auteurs : Catherine TUVBLAD, Auteur ; Martin GRANN, Auteur ; Paul LICHTENSTEIN, Auteur Année de publication : 2006 Article en page(s) : p.734–743 Langues : Anglais (eng) Mots-clés : Antisocial-behavior socioeconomic-status twin-study sex-differences gene–environment-interaction Index. décimale : PER Périodiques Résumé : Background: Socioeconomic status is often assumed to be of importance for the development of antisocial behavior, yet it explains only a fraction of the variance. One explanation for this paradox could be that socioeconomic status moderates the influence of genetic and environmental effects on antisocial behavior. Method: TCHAD is a Swedish longitudinal population-based twin study that contains 1,480 twin pairs born 1985–1986. The present study included 1,133 twin pairs, aged 16–17 years. Antisocial behavior was measured through self-report. Family socioeconomic status was assessed by parental-reported education and occupational status. Neighborhood socioeconomic conditions were assessed using five aggregated level variables: ethnic diversity, basic educational level, unemployment level, buying power, and crime-rate. We used structural equation modeling to test whether socioeconomic status interacted with latent genetic and environmental effects for antisocial behavior. Results: Genetic influences on antisocial behavior were more important in adolescents in socioeconomically more advantaged environments, whereas the shared environment was higher in adolescents in socioeconomically less advantaged environments. Heritability for antisocial behavior was higher in girls than in boys, irrespective of socioeconomic background. Conclusions: Our results suggest that different intervention policies should be considered in different socioeconomic areas. In socioeconomically advantaged areas, it might be more fruitful to focus on individually based preventions and treatments. In socioeconomically disadvantaged areas, intervention and prevention policies might be more effective on a community level, to account for shared environmental risk factors. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2005.01552.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=758 [article] Heritability for adolescent antisocial behavior differs with socioeconomic status: gene–environment interaction [Texte imprimé et/ou numérique] / Catherine TUVBLAD, Auteur ; Martin GRANN, Auteur ; Paul LICHTENSTEIN, Auteur . - 2006 . - p.734–743. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 47-7 (July 2006) . - p.734–743 Mots-clés : Antisocial-behavior socioeconomic-status twin-study sex-differences gene–environment-interaction Index. décimale : PER Périodiques Résumé : Background: Socioeconomic status is often assumed to be of importance for the development of antisocial behavior, yet it explains only a fraction of the variance. One explanation for this paradox could be that socioeconomic status moderates the influence of genetic and environmental effects on antisocial behavior. Method: TCHAD is a Swedish longitudinal population-based twin study that contains 1,480 twin pairs born 1985–1986. The present study included 1,133 twin pairs, aged 16–17 years. Antisocial behavior was measured through self-report. Family socioeconomic status was assessed by parental-reported education and occupational status. Neighborhood socioeconomic conditions were assessed using five aggregated level variables: ethnic diversity, basic educational level, unemployment level, buying power, and crime-rate. We used structural equation modeling to test whether socioeconomic status interacted with latent genetic and environmental effects for antisocial behavior. Results: Genetic influences on antisocial behavior were more important in adolescents in socioeconomically more advantaged environments, whereas the shared environment was higher in adolescents in socioeconomically less advantaged environments. Heritability for antisocial behavior was higher in girls than in boys, irrespective of socioeconomic background. Conclusions: Our results suggest that different intervention policies should be considered in different socioeconomic areas. In socioeconomically advantaged areas, it might be more fruitful to focus on individually based preventions and treatments. In socioeconomically disadvantaged areas, intervention and prevention policies might be more effective on a community level, to account for shared environmental risk factors. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2005.01552.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=758

Psychopathic personality development from ages 9 to 18: Genes and environment / Catherine TUVBLAD in Development and Psychopathology, 28-1 (February 2016)  

Public ISBD [article]  inDevelopment and Psychopathology > 28-1 (February 2016) . - p.27-44 Titre : Psychopathic personality development from ages 9 to 18: Genes and environment Type de document : Texte imprimé et/ou numérique Auteurs : Catherine TUVBLAD, Auteur ; Pan WANG, Auteur ; Serena BEZDJIAN, Auteur ; Adrian RAINE, Auteur ; Laura A. BAKER, Auteur Article en page(s) : p.27-44 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The genetic and environmental etiology of individual differences was examined in initial level and change in psychopathic personality from ages 9 to 18 years. A piecewise growth curve model, in which the first change score (G1) influenced all ages (9–10, 11–13, 14–15, and 16–18 years) and the second change score (G2) only influenced ages 14–15 and 16–18 years, fit the data better did than the standard single slope model, suggesting a turning point from childhood to adolescence. The results indicated that variations in levels and both change scores were mainly due to genetic (A) and nonshared environmental (E) influences (i.e., AE structure for G0, G1, and G2). No sex differences were found except on the mean values of level and change scores. Based on caregiver ratings, about 81% of variance in G0, 89% of variance in G1, and 94% of variance in G2 were explained by genetic factors, whereas for youth self-reports, these three proportions were 94%, 71%, and 66%, respectively. The larger contribution of genetic variance and covariance in caregiver ratings than in youth self-reports may suggest that caregivers considered the changes in their children to be more similar as compared to how the children viewed themselves. En ligne : http://dx.doi.org/10.1017/S0954579415000267 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278 [article] Psychopathic personality development from ages 9 to 18: Genes and environment [Texte imprimé et/ou numérique] / Catherine TUVBLAD, Auteur ; Pan WANG, Auteur ; Serena BEZDJIAN, Auteur ; Adrian RAINE, Auteur ; Laura A. BAKER, Auteur . - p.27-44. Langues : Anglais (eng) in Development and Psychopathology > 28-1 (February 2016) . - p.27-44 Index. décimale : PER Périodiques Résumé : The genetic and environmental etiology of individual differences was examined in initial level and change in psychopathic personality from ages 9 to 18 years. A piecewise growth curve model, in which the first change score (G1) influenced all ages (9–10, 11–13, 14–15, and 16–18 years) and the second change score (G2) only influenced ages 14–15 and 16–18 years, fit the data better did than the standard single slope model, suggesting a turning point from childhood to adolescence. The results indicated that variations in levels and both change scores were mainly due to genetic (A) and nonshared environmental (E) influences (i.e., AE structure for G0, G1, and G2). No sex differences were found except on the mean values of level and change scores. Based on caregiver ratings, about 81% of variance in G0, 89% of variance in G1, and 94% of variance in G2 were explained by genetic factors, whereas for youth self-reports, these three proportions were 94%, 71%, and 66%, respectively. The larger contribution of genetic variance and covariance in caregiver ratings than in youth self-reports may suggest that caregivers considered the changes in their children to be more similar as compared to how the children viewed themselves. En ligne : http://dx.doi.org/10.1017/S0954579415000267 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278

Pursuing the developmental aims of the triarchic model of psychopathy: Creation and validation of triarchic scales for use in the USC: RFAB longitudinal twin project / Bridget M. BERTOLDI in Development and Psychopathology, 34-3 (August 2022)  

Public ISBD [article]  inDevelopment and Psychopathology > 34-3 (August 2022) . - p.1088-1103 Titre : Pursuing the developmental aims of the triarchic model of psychopathy: Creation and validation of triarchic scales for use in the USC: RFAB longitudinal twin project Type de document : Texte imprimé et/ou numérique Auteurs : Bridget M. BERTOLDI, Auteur ; Emily R. PERKINS, Auteur ; Catherine TUVBLAD, Auteur ; Sofi OSKARSSON, Auteur ; Mark D. KRAMER, Auteur ; Robert D. LATZMAN, Auteur ; Laura A. BAKER, Auteur ; Adrian RAINE, Auteur ; Christopher J. PATRICK, Auteur Article en page(s) : p.1088-1103 Langues : Anglais (eng) Mots-clés : antisocial behavior  longitudinal design  psychopathy  triarchic model  twin Index. décimale : PER Périodiques Résumé : The triarchic model was advanced as an integrative, trait-based framework for investigating psychopathy using different assessment methods and across developmental periods. Recent research has shown that the triarchic traits of boldness, meanness, and disinhibition can be operationalized effectively in youth, but longitudinal research is needed to realize the model's potential to advance developmental understanding of psychopathy. We report on the creation and validation of scale measures of the triarchic traits using questionnaire items available in the University of Southern California Risk Factors for Antisocial Behavior (RFAB) project, a large-scale longitudinal study of the development of antisocial behavior that includes measures from multiple modalities (self-report, informant rating, clinical-diagnostic, task-behavioral, physiological). Using a construct-rating and psychometric refinement approach, we developed triarchic scales that showed acceptable reliability, expected intercorrelations, and good temporal stability. The scales showed theory-consistent relations with external criteria including measures of psychopathy, internalizing/externalizing psychopathology, antisocial behavior, and substance use. Findings demonstrate the viability of measuring triarchic traits in the RFAB sample, extend the known nomological network of these traits into the developmental realm, and provide a foundation for follow-up studies examining the etiology of psychopathic traits and their relations with multimodal measures of cognitive-affective function and proneness to clinical problems. En ligne : http://dx.doi.org/10.1017/S0954579420002060 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=485 [article] Pursuing the developmental aims of the triarchic model of psychopathy: Creation and validation of triarchic scales for use in the USC: RFAB longitudinal twin project [Texte imprimé et/ou numérique] / Bridget M. BERTOLDI, Auteur ; Emily R. PERKINS, Auteur ; Catherine TUVBLAD, Auteur ; Sofi OSKARSSON, Auteur ; Mark D. KRAMER, Auteur ; Robert D. LATZMAN, Auteur ; Laura A. BAKER, Auteur ; Adrian RAINE, Auteur ; Christopher J. PATRICK, Auteur . - p.1088-1103. Langues : Anglais (eng) in Development and Psychopathology > 34-3 (August 2022) . - p.1088-1103 Mots-clés : antisocial behavior  longitudinal design  psychopathy  triarchic model  twin Index. décimale : PER Périodiques Résumé : The triarchic model was advanced as an integrative, trait-based framework for investigating psychopathy using different assessment methods and across developmental periods. Recent research has shown that the triarchic traits of boldness, meanness, and disinhibition can be operationalized effectively in youth, but longitudinal research is needed to realize the model's potential to advance developmental understanding of psychopathy. We report on the creation and validation of scale measures of the triarchic traits using questionnaire items available in the University of Southern California Risk Factors for Antisocial Behavior (RFAB) project, a large-scale longitudinal study of the development of antisocial behavior that includes measures from multiple modalities (self-report, informant rating, clinical-diagnostic, task-behavioral, physiological). Using a construct-rating and psychometric refinement approach, we developed triarchic scales that showed acceptable reliability, expected intercorrelations, and good temporal stability. The scales showed theory-consistent relations with external criteria including measures of psychopathy, internalizing/externalizing psychopathology, antisocial behavior, and substance use. Findings demonstrate the viability of measuring triarchic traits in the RFAB sample, extend the known nomological network of these traits into the developmental realm, and provide a foundation for follow-up studies examining the etiology of psychopathic traits and their relations with multimodal measures of cognitive-affective function and proneness to clinical problems. En ligne : http://dx.doi.org/10.1017/S0954579420002060 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=485

Research Review: The strength of the genetic overlap between ADHD and other psychiatric symptoms - a systematic review and meta-analysis / Anneli ANDERSSON in Journal of Child Psychology and Psychiatry, 61-11 (November 2020)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 61-11 (November 2020) . - p.1173-1183 Titre : Research Review: The strength of the genetic overlap between ADHD and other psychiatric symptoms - a systematic review and meta-analysis Type de document : Texte imprimé et/ou numérique Auteurs : Anneli ANDERSSON, Auteur ; Catherine TUVBLAD, Auteur ; Qi CHEN, Auteur ; Ebba DU RIETZ, Auteur ; Samuele CORTESE, Auteur ; Ralf KUJA-HALKOLA, Auteur ; Henrik LARSSON, Auteur Article en page(s) : p.1173-1183 Langues : Anglais (eng) Mots-clés : Adhd  externalizing  genetic  internalizing  neurodevelopmental  overlap  twins Index. décimale : PER Périodiques Résumé : BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) frequently co-occurs with other psychiatric disorders. Twin studies have established that these co-occurrences are in part due to shared genetic risks. However, the strength of these genetic overlaps and the potential heterogeneity accounted for by type of psychiatric symptoms, age, and methods of assessment remain unclear. We conducted a systematic review to fill this gap. METHODS: We searched PubMed, PsycINFO, Embase, and Web of Science until March 07, 2019. Genetic correlations (r(g) ) were used as effect size measures. RESULTS: A total of 31 independent studies fulfilled the inclusion criteria. The pooled estimates showed that the associations between ADHD and other psychiatric symptoms were partly explained by shared genetic factors, with a pooled genetic correlation of 0.50, 95% confidence interval: 0.46-0.60. The genetic correlations (r(g) ) between ADHD and externalizing (r(g)  = .49 [0.37-0.61]), internalizing (r(g)  = .50 [0.39-0.69]), and neurodevelopmental (r(g)  = .56 [0.47-0.66]) symptoms were similar in magnitude. The genetic correlations in childhood and adulthood were r(g)  = .53 (0.43-0.63) and r(g)  = .51 (0.44-0.56), respectively. For methods of assessment, the genetic correlations were also similar in strength, self-reports r(g)  = .52 (0.47-0.58), other informants r(g)  = .55 (0.41-0.69), and combined raters r(g)  = .50 (0.33-0.65). CONCLUSIONS: These findings indicate that the co-occurrence of externalizing, internalizing, and neurodevelopmental disorder symptoms in individuals with ADHD symptoms in part is due to a shared genetic risk. En ligne : http://dx.doi.org/10.1111/jcpp.13233 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434 [article] Research Review: The strength of the genetic overlap between ADHD and other psychiatric symptoms - a systematic review and meta-analysis [Texte imprimé et/ou numérique] / Anneli ANDERSSON, Auteur ; Catherine TUVBLAD, Auteur ; Qi CHEN, Auteur ; Ebba DU RIETZ, Auteur ; Samuele CORTESE, Auteur ; Ralf KUJA-HALKOLA, Auteur ; Henrik LARSSON, Auteur . - p.1173-1183. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 61-11 (November 2020) . - p.1173-1183 Mots-clés : Adhd  externalizing  genetic  internalizing  neurodevelopmental  overlap  twins Index. décimale : PER Périodiques Résumé : BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) frequently co-occurs with other psychiatric disorders. Twin studies have established that these co-occurrences are in part due to shared genetic risks. However, the strength of these genetic overlaps and the potential heterogeneity accounted for by type of psychiatric symptoms, age, and methods of assessment remain unclear. We conducted a systematic review to fill this gap. METHODS: We searched PubMed, PsycINFO, Embase, and Web of Science until March 07, 2019. Genetic correlations (r(g) ) were used as effect size measures. RESULTS: A total of 31 independent studies fulfilled the inclusion criteria. The pooled estimates showed that the associations between ADHD and other psychiatric symptoms were partly explained by shared genetic factors, with a pooled genetic correlation of 0.50, 95% confidence interval: 0.46-0.60. The genetic correlations (r(g) ) between ADHD and externalizing (r(g)  = .49 [0.37-0.61]), internalizing (r(g)  = .50 [0.39-0.69]), and neurodevelopmental (r(g)  = .56 [0.47-0.66]) symptoms were similar in magnitude. The genetic correlations in childhood and adulthood were r(g)  = .53 (0.43-0.63) and r(g)  = .51 (0.44-0.56), respectively. For methods of assessment, the genetic correlations were also similar in strength, self-reports r(g)  = .52 (0.47-0.58), other informants r(g)  = .55 (0.41-0.69), and combined raters r(g)  = .50 (0.33-0.65). CONCLUSIONS: These findings indicate that the co-occurrence of externalizing, internalizing, and neurodevelopmental disorder symptoms in individuals with ADHD symptoms in part is due to a shared genetic risk. En ligne : http://dx.doi.org/10.1111/jcpp.13233 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434

Resting heart rate and the development of antisocial behavior from age 9 to 14: Genetic and environmental influences / Laura A. BAKER in Development and Psychopathology, 21-3 (August 2009)  

Permalink

Triarchic traits as risk versus protective factors for ADHD symptomatology: A prospective longitudinal investigation / Elizabeth S. M. Chan ; Emily R. PERKINS ; Bridget M. BERTOLDI ; Kelsey L. Lowman ; Elia F. SOTO ; Catherine TUVBLAD ; Sofi OSKARSSON ; Laura A. BAKER ; Christopher J. PATRICK in Development and Psychopathology, 37-1 (February 2025)  

Permalink

---

1 (1 - 7 / 7)