Correlates of Attachment Perceptions in Parents of Children with Autism Spectrum Disorders / Sabrina J. GOODMAN in Journal of Autism and Developmental Disorders, 42-10 (October 2012)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 42-10 (October 2012) . - p.2056-2066 Titre : Correlates of Attachment Perceptions in Parents of Children with Autism Spectrum Disorders Type de document : texte imprimé Auteurs : Sabrina J. GOODMAN, Auteur ; David S. GLENWICK, Auteur Année de publication : 2012 Article en page(s) : p.2056-2066 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Attachment  Parenting stress  Parent cognitions  Parent perceptions Index. décimale : PER Périodiques Résumé : This study explored the relationship between parents’ perceptions of their child’s attachment to them and parents’ own affective attachment to their child, as well the relationship of these constructs to parenting stress, parent-rated child functional impairment, and parenting sense of competence. Mothers (n = 76) and fathers (n = 30) of children ages 2–10 with autism spectrum disorders participated. Overall, parents’ affective attachment to their child was more consistently related to other aspects of their parenting experiences than were their perceptions of their child’s attachment to them. Also, perceptions of child-to-parent attachment were related to other aspects of parenting for fathers more than for mothers. Implications for parenting interventions and future research, such as longitudinal investigations, are discussed. En ligne : http://dx.doi.org/10.1007/s10803-012-1453-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=180 [article] Correlates of Attachment Perceptions in Parents of Children with Autism Spectrum Disorders [texte imprimé] / Sabrina J. GOODMAN, Auteur ; David S. GLENWICK, Auteur . - 2012 . - p.2056-2066. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 42-10 (October 2012) . - p.2056-2066 Mots-clés : Autism spectrum disorders  Attachment  Parenting stress  Parent cognitions  Parent perceptions Index. décimale : PER Périodiques Résumé : This study explored the relationship between parents’ perceptions of their child’s attachment to them and parents’ own affective attachment to their child, as well the relationship of these constructs to parenting stress, parent-rated child functional impairment, and parenting sense of competence. Mothers (n = 76) and fathers (n = 30) of children ages 2–10 with autism spectrum disorders participated. Overall, parents’ affective attachment to their child was more consistently related to other aspects of their parenting experiences than were their perceptions of their child’s attachment to them. Also, perceptions of child-to-parent attachment were related to other aspects of parenting for fathers more than for mothers. Implications for parenting interventions and future research, such as longitudinal investigations, are discussed. En ligne : http://dx.doi.org/10.1007/s10803-012-1453-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=180

DNA Methylation of the Oxytocin Receptor Across Neurodevelopmental Disorders / Michelle T. SIU in Journal of Autism and Developmental Disorders, 51-10 (October 2021)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 51-10 (October 2021) . - p.3610-3623 Titre : DNA Methylation of the Oxytocin Receptor Across Neurodevelopmental Disorders Type de document : texte imprimé Auteurs : Michelle T. SIU, Auteur ; Sabrina J. GOODMAN, Auteur ; Isaac YELLAN, Auteur ; Darci T. BUTCHER, Auteur ; Maryam JANGJOO, Auteur ; Daria GRAFODATSKAYA, Auteur ; Rageen RAJENDRAM, Auteur ; Youliang LOU, Auteur ; Rujun ZHANG, Auteur ; Chunhua ZHAO, Auteur ; Robert NICOLSON, Auteur ; Stelios GEORGIADES, Auteur ; Peter SZATMARI, Auteur ; Stephen SCHERER, Auteur ; Wendy ROBERTS, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Rosanna WEKSBERG, Auteur Article en page(s) : p.3610-3623 Langues : Anglais (eng) Mots-clés : Attention Deficit Disorder with Hyperactivity/genetics  Autism Spectrum Disorder/genetics  DNA Methylation  Female  Humans  Male  Obsessive-Compulsive Disorder  Oxytocin/metabolism  Receptors, Oxytocin/genetics  Adhd  Asd  Ocd  Oxtr Index. décimale : PER Périodiques Résumé : Many neurodevelopmental disorders (NDDs) share common learning and behavioural impairments, as well as features such as dysregulation of the oxytocin hormone. Here, we examined DNA methylation (DNAm) in the 1st intron of the oxytocin receptor gene, OXTR, in patients with autism spectrum (ASD), attention deficit and hyperactivity (ADHD) and obsessive compulsive (OCD) disorders. DNAm of OXTR was assessed for cohorts of ASD (blood), ADHD (saliva), OCD (saliva), which uncovered sex-specific DNAm differences compared to neurotypical, tissue-matched controls. Individuals with ASD or ADHD exhibiting extreme DNAm values had lower IQ and more social problems, respectively, than those with DNAm within normative ranges. This suggests that OXTR DNAm patterns are altered across NDDs and may be correlated with common clinical outcomes. En ligne : http://dx.doi.org/10.1007/s10803-020-04792-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=453 [article] DNA Methylation of the Oxytocin Receptor Across Neurodevelopmental Disorders [texte imprimé] / Michelle T. SIU, Auteur ; Sabrina J. GOODMAN, Auteur ; Isaac YELLAN, Auteur ; Darci T. BUTCHER, Auteur ; Maryam JANGJOO, Auteur ; Daria GRAFODATSKAYA, Auteur ; Rageen RAJENDRAM, Auteur ; Youliang LOU, Auteur ; Rujun ZHANG, Auteur ; Chunhua ZHAO, Auteur ; Robert NICOLSON, Auteur ; Stelios GEORGIADES, Auteur ; Peter SZATMARI, Auteur ; Stephen SCHERER, Auteur ; Wendy ROBERTS, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Rosanna WEKSBERG, Auteur . - p.3610-3623. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 51-10 (October 2021) . - p.3610-3623 Mots-clés : Attention Deficit Disorder with Hyperactivity/genetics  Autism Spectrum Disorder/genetics  DNA Methylation  Female  Humans  Male  Obsessive-Compulsive Disorder  Oxytocin/metabolism  Receptors, Oxytocin/genetics  Adhd  Asd  Ocd  Oxtr Index. décimale : PER Périodiques Résumé : Many neurodevelopmental disorders (NDDs) share common learning and behavioural impairments, as well as features such as dysregulation of the oxytocin hormone. Here, we examined DNA methylation (DNAm) in the 1st intron of the oxytocin receptor gene, OXTR, in patients with autism spectrum (ASD), attention deficit and hyperactivity (ADHD) and obsessive compulsive (OCD) disorders. DNAm of OXTR was assessed for cohorts of ASD (blood), ADHD (saliva), OCD (saliva), which uncovered sex-specific DNAm differences compared to neurotypical, tissue-matched controls. Individuals with ASD or ADHD exhibiting extreme DNAm values had lower IQ and more social problems, respectively, than those with DNAm within normative ranges. This suggests that OXTR DNAm patterns are altered across NDDs and may be correlated with common clinical outcomes. En ligne : http://dx.doi.org/10.1007/s10803-020-04792-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=453

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