Association between autism spectrum disorder and inflammatory bowel disease: A systematic review and meta-analysis / J. Y. KIM in Autism Research, 15-2 (February 2022)  

Public ISBD [article]  inAutism Research > 15-2 (February 2022) . - p.340-352 Titre : Association between autism spectrum disorder and inflammatory bowel disease: A systematic review and meta-analysis Type de document : Texte imprimé et/ou numérique Auteurs : J. Y. KIM, Auteur ; M. J. CHOI, Auteur ; S. HA, Auteur ; J. HWANG, Auteur ; A. KOYANAGI, Auteur ; E. DRAGIOTI, Auteur ; J. RADUA, Auteur ; L. SMITH, Auteur ; L. JACOB, Auteur ; G. S. DE PABLO, Auteur ; S. W. LEE, Auteur ; D. K. YON, Auteur ; T. THOMPSON, Auteur ; S. CORTESE, Auteur ; G. LOLLO, Auteur ; C. S. LIANG, Auteur ; C. S. CHU, Auteur ; P. FUSAR-POLI, Auteur ; Keun-Ah CHEON, Auteur ; J. I. SHIN, Auteur ; M. SOLMI, Auteur Article en page(s) : p.340-352 Langues : Anglais (eng) Mots-clés : Crohn's disease  autism spectrum disorder  inflammatory bowel disease  meta-analysis  ulcerative colitis Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorder (ASD) are frequently diagnosed with co-occurring medical conditions including inflammatory bowel disease (IBD). To investigate the association, we conducted a systematic review registered in PROSPERO (ID:CRD42021236263) with a random-effects meta-analysis. We searched PubMed, Embase, and PsycInfo (last search on January 25, 2021), and manually searched relevant publications. We included observational studies measuring the association between ASD and IBD. The primary outcome was the association (odds ratio, OR) between ASD and later development of IBD. Sensitivity analyses were conducted by quality, confounding adjustment, and study design. We performed meta-regression analyses and assessed heterogeneity, publication bias, and quality of studies with the Newcastle-Ottawa Scale. Overall, we included six studies consisting of eight datasets, including over 11 million participants. We found that ASD was significantly associated with subsequent incident IBD (any IBD, OR = 1.66, 95% confidence interval[CI] = 1.25-2.21, p  En ligne : http://dx.doi.org/10.1002/aur.2656 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450 [article] Association between autism spectrum disorder and inflammatory bowel disease: A systematic review and meta-analysis [Texte imprimé et/ou numérique] / J. Y. KIM, Auteur ; M. J. CHOI, Auteur ; S. HA, Auteur ; J. HWANG, Auteur ; A. KOYANAGI, Auteur ; E. DRAGIOTI, Auteur ; J. RADUA, Auteur ; L. SMITH, Auteur ; L. JACOB, Auteur ; G. S. DE PABLO, Auteur ; S. W. LEE, Auteur ; D. K. YON, Auteur ; T. THOMPSON, Auteur ; S. CORTESE, Auteur ; G. LOLLO, Auteur ; C. S. LIANG, Auteur ; C. S. CHU, Auteur ; P. FUSAR-POLI, Auteur ; Keun-Ah CHEON, Auteur ; J. I. SHIN, Auteur ; M. SOLMI, Auteur . - p.340-352. Langues : Anglais (eng) in Autism Research > 15-2 (February 2022) . - p.340-352 Mots-clés : Crohn's disease  autism spectrum disorder  inflammatory bowel disease  meta-analysis  ulcerative colitis Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorder (ASD) are frequently diagnosed with co-occurring medical conditions including inflammatory bowel disease (IBD). To investigate the association, we conducted a systematic review registered in PROSPERO (ID:CRD42021236263) with a random-effects meta-analysis. We searched PubMed, Embase, and PsycInfo (last search on January 25, 2021), and manually searched relevant publications. We included observational studies measuring the association between ASD and IBD. The primary outcome was the association (odds ratio, OR) between ASD and later development of IBD. Sensitivity analyses were conducted by quality, confounding adjustment, and study design. We performed meta-regression analyses and assessed heterogeneity, publication bias, and quality of studies with the Newcastle-Ottawa Scale. Overall, we included six studies consisting of eight datasets, including over 11 million participants. We found that ASD was significantly associated with subsequent incident IBD (any IBD, OR = 1.66, 95% confidence interval[CI] = 1.25-2.21, p  En ligne : http://dx.doi.org/10.1002/aur.2656 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450

Editorial Perspective: Challenges of research focusing on child and adolescent mental health during the COVID-19 era: what studies are needed? / M. SOLMI in Journal of Child Psychology and Psychiatry, 63-1 (January 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-1 (January 2022) . - p.122-125 Titre : Editorial Perspective: Challenges of research focusing on child and adolescent mental health during the COVID-19 era: what studies are needed? Type de document : Texte imprimé et/ou numérique Auteurs : M. SOLMI, Auteur ; S. CORTESE, Auteur ; C. U. CORRELL, Auteur Article en page(s) : p.122-125 Langues : Anglais (eng) Mots-clés : Adolescent  Covid-19  Child  Humans  Mental Health  Pandemics  Quality of Life  SARS-CoV-2 Index. décimale : PER Périodiques Résumé : This editorial perspective focuses on the challenges of research on child and adolescent mental health during the COVID-19 pandemic. Common limitations of published/ongoing studies are (i) being conducted in one or few countries, (ii) the survey being available in one or few languages, (iii) targeting selected samples (e.g., clinical populations and health workers) rather than the general population, (iv) only recruiting/reporting on non-representative samples, (v) focusing often on a restricted set of mental health outcomes, missing the broader picture of mental and physical health, quality of life and functioning, (vi) failing to use a longitudinal design and (vii) collecting only parental ratings or self-rated questionnaires from children and adolescents, but not both. We discuss how the Collaborative Outcomes Study on Health and Functioning during Infection Times (COH-FIT) was designed to address some of these challenges, also highlighting its limitations. En ligne : http://dx.doi.org/10.1111/jcpp.13478 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457 [article] Editorial Perspective: Challenges of research focusing on child and adolescent mental health during the COVID-19 era: what studies are needed? [Texte imprimé et/ou numérique] / M. SOLMI, Auteur ; S. CORTESE, Auteur ; C. U. CORRELL, Auteur . - p.122-125. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-1 (January 2022) . - p.122-125 Mots-clés : Adolescent  Covid-19  Child  Humans  Mental Health  Pandemics  Quality of Life  SARS-CoV-2 Index. décimale : PER Périodiques Résumé : This editorial perspective focuses on the challenges of research on child and adolescent mental health during the COVID-19 pandemic. Common limitations of published/ongoing studies are (i) being conducted in one or few countries, (ii) the survey being available in one or few languages, (iii) targeting selected samples (e.g., clinical populations and health workers) rather than the general population, (iv) only recruiting/reporting on non-representative samples, (v) focusing often on a restricted set of mental health outcomes, missing the broader picture of mental and physical health, quality of life and functioning, (vi) failing to use a longitudinal design and (vii) collecting only parental ratings or self-rated questionnaires from children and adolescents, but not both. We discuss how the Collaborative Outcomes Study on Health and Functioning during Infection Times (COH-FIT) was designed to address some of these challenges, also highlighting its limitations. En ligne : http://dx.doi.org/10.1111/jcpp.13478 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=457

Practitioner Review: Treatment of chronic insomnia in children and adolescents with neurodevelopmental disabilities / O. BRUNI in Journal of Child Psychology and Psychiatry, 59-5 (May 2018)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 59-5 (May 2018) . - p.489-508 Titre : Practitioner Review: Treatment of chronic insomnia in children and adolescents with neurodevelopmental disabilities Type de document : Texte imprimé et/ou numérique Auteurs : O. BRUNI, Auteur ; M. ANGRIMAN, Auteur ; F. CALISTI, Auteur ; A. COMANDINI, Auteur ; G. ESPOSITO, Auteur ; S. CORTESE, Auteur ; R. FERRI, Auteur Article en page(s) : p.489-508 Langues : Anglais (eng) Mots-clés : Sleep disorders  drug effects  insomnia  neurodevelopmental disorders Index. décimale : PER Périodiques Résumé : BACKGROUND: Sleep disturbances, in particular insomnia, represent a common problem in children with neurodevelopmental disabilities (NDDs). Currently, there are no approved medications for insomnia in children by the US Food and Drug Administration or European Medicines Agency and therefore they are prescribed off-label. We critically reviewed pediatric literature on drugs as well as nonpharmacological (behavioral) interventions used for sleep disturbances in children with NDDs. METHODS: PubMed, Ovid (including PsycINFO, Ovid MEDLINE((R)) , and Embase), and Web of Knowledge databases were searched through February 12, 2017, with no language restrictions. Two authors independently and blindly performed the screening. RESULTS: Good sleep practices and behavioral interventions, supported by moderate-to-low level evidence, are the first recommended treatments for pediatric insomnia but they are often challenging to implement. Antihistamine agents, such as hydroxyzine or diphenhydramine, are the most widely prescribed sedatives in the pediatric practice but evidence supporting their use is still limited. An increasing body of evidence supports melatonin as the safest choice for children with NDDs. Benzodiazepines are not recommended in children and should only be used for transient insomnia, especially if daytime anxiety is present. Only few studies have been carried out in children's and adolescents' zolpidem, zaleplon, and eszopiclone, with contrasting results. Limited evidence supports the use of alpha-agonists such as clonidine to improve sleep onset latency, especially in attention deficit/hyperactivity disorder subjects. Tricyclic antidepressants, used in adults with insomnia, are not recommended in children because of their safety profile. Trazodone and mirtazapine hold promise but require further studies. CONCLUSIONS: Here, we provided a tentative guide for the use of drugs for insomnia in children with NDDs. Well-controlled studies employing both objective polysomnography and subjective sleep measures are needed to determine the efficacy, effectiveness, and safety of the currently prescribed pediatric sleep medicines in children with NDDs. En ligne : http://dx.doi.org/10.1111/jcpp.12812 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=359 [article] Practitioner Review: Treatment of chronic insomnia in children and adolescents with neurodevelopmental disabilities [Texte imprimé et/ou numérique] / O. BRUNI, Auteur ; M. ANGRIMAN, Auteur ; F. CALISTI, Auteur ; A. COMANDINI, Auteur ; G. ESPOSITO, Auteur ; S. CORTESE, Auteur ; R. FERRI, Auteur . - p.489-508. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 59-5 (May 2018) . - p.489-508 Mots-clés : Sleep disorders  drug effects  insomnia  neurodevelopmental disorders Index. décimale : PER Périodiques Résumé : BACKGROUND: Sleep disturbances, in particular insomnia, represent a common problem in children with neurodevelopmental disabilities (NDDs). Currently, there are no approved medications for insomnia in children by the US Food and Drug Administration or European Medicines Agency and therefore they are prescribed off-label. We critically reviewed pediatric literature on drugs as well as nonpharmacological (behavioral) interventions used for sleep disturbances in children with NDDs. METHODS: PubMed, Ovid (including PsycINFO, Ovid MEDLINE((R)) , and Embase), and Web of Knowledge databases were searched through February 12, 2017, with no language restrictions. Two authors independently and blindly performed the screening. RESULTS: Good sleep practices and behavioral interventions, supported by moderate-to-low level evidence, are the first recommended treatments for pediatric insomnia but they are often challenging to implement. Antihistamine agents, such as hydroxyzine or diphenhydramine, are the most widely prescribed sedatives in the pediatric practice but evidence supporting their use is still limited. An increasing body of evidence supports melatonin as the safest choice for children with NDDs. Benzodiazepines are not recommended in children and should only be used for transient insomnia, especially if daytime anxiety is present. Only few studies have been carried out in children's and adolescents' zolpidem, zaleplon, and eszopiclone, with contrasting results. Limited evidence supports the use of alpha-agonists such as clonidine to improve sleep onset latency, especially in attention deficit/hyperactivity disorder subjects. Tricyclic antidepressants, used in adults with insomnia, are not recommended in children because of their safety profile. Trazodone and mirtazapine hold promise but require further studies. CONCLUSIONS: Here, we provided a tentative guide for the use of drugs for insomnia in children with NDDs. Well-controlled studies employing both objective polysomnography and subjective sleep measures are needed to determine the efficacy, effectiveness, and safety of the currently prescribed pediatric sleep medicines in children with NDDs. En ligne : http://dx.doi.org/10.1111/jcpp.12812 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=359

Research Review: A systematic review and meta-analysis of sex/gender differences in social interaction and communication in autistic and nonautistic children and adolescents / H. WOOD-DOWNIE in Journal of Child Psychology and Psychiatry, 62-8 (August 2021)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 62-8 (August 2021) . - p.922-936 Titre : Research Review: A systematic review and meta-analysis of sex/gender differences in social interaction and communication in autistic and nonautistic children and adolescents Type de document : Texte imprimé et/ou numérique Auteurs : H. WOOD-DOWNIE, Auteur ; B. WONG, Auteur ; H. KOVSHOFF, Auteur ; S. CORTESE, Auteur ; Julie A. HADWIN, Auteur Article en page(s) : p.922-936 Langues : Anglais (eng) Mots-clés : Adolescent  Adult  Autism Spectrum Disorder  Autistic Disorder  Child  Communication  Cross-Sectional Studies  Female  Humans  Male  Sex Factors  Social Interaction  Autism spectrum disorders  Dsm  gender difference  meta-analysis  sex differences Index. décimale : PER Périodiques Résumé : BACKGROUND: Evidence increasingly suggests that ASD manifests differently in females than males. Previous reviews investigating sex/gender differences in social interaction and social communication have focused at the level of broad constructs (e.g. comparing algorithm scores from pre-existing diagnostic instruments) and have typically reported no significant differences between males and females. However, a number of individual studies have found sex/gender differences in narrow construct domains. METHODS: We conducted a systematic review and random effects model meta-analyses (in January 2019 and updated January 2020) that investigated sex/gender differences in narrow construct measures of social communication and interaction in autistic and nonautistic children and adolescents, and adults. Study quality was appraised using the Appraisal Tool for Cross-Sectional Studies (AXIS, BMJ Open, 6, 2016, 1). RESULTS: Across 16 studies (including 2,730 participants), the analysis found that female (vs. male) individuals with ASD had significantly better social interaction and social communication skills (SMD = 0.39, p < .001), which was reflective of a similar sex/gender profile in nonautistic individuals (SMD = 0.35, p < .001). Nonautistic males had significantly better social interaction and communication than males with ASD (SMD = 0.77, p < .001). Nonautistic females also had significantly better social interaction and communication than females with ASD (SMD = 0.72, p  <.001). Nonautistic males had better social interaction and communication than females with ASD, though this difference was not significant (SMD = 0.30, p = .07). CONCLUSIONS: This systematic review and meta-analysis highlighted important sex/gender differences in social interaction and communication for individuals with ASD, likely not captured by pre-existing diagnostic instruments, which potentially contribute to the under recognition of autism in females, and may need to be reflected in the diagnostic process. En ligne : http://dx.doi.org/10.1111/jcpp.13337 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456 [article] Research Review: A systematic review and meta-analysis of sex/gender differences in social interaction and communication in autistic and nonautistic children and adolescents [Texte imprimé et/ou numérique] / H. WOOD-DOWNIE, Auteur ; B. WONG, Auteur ; H. KOVSHOFF, Auteur ; S. CORTESE, Auteur ; Julie A. HADWIN, Auteur . - p.922-936. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 62-8 (August 2021) . - p.922-936 Mots-clés : Adolescent  Adult  Autism Spectrum Disorder  Autistic Disorder  Child  Communication  Cross-Sectional Studies  Female  Humans  Male  Sex Factors  Social Interaction  Autism spectrum disorders  Dsm  gender difference  meta-analysis  sex differences Index. décimale : PER Périodiques Résumé : BACKGROUND: Evidence increasingly suggests that ASD manifests differently in females than males. Previous reviews investigating sex/gender differences in social interaction and social communication have focused at the level of broad constructs (e.g. comparing algorithm scores from pre-existing diagnostic instruments) and have typically reported no significant differences between males and females. However, a number of individual studies have found sex/gender differences in narrow construct domains. METHODS: We conducted a systematic review and random effects model meta-analyses (in January 2019 and updated January 2020) that investigated sex/gender differences in narrow construct measures of social communication and interaction in autistic and nonautistic children and adolescents, and adults. Study quality was appraised using the Appraisal Tool for Cross-Sectional Studies (AXIS, BMJ Open, 6, 2016, 1). RESULTS: Across 16 studies (including 2,730 participants), the analysis found that female (vs. male) individuals with ASD had significantly better social interaction and social communication skills (SMD = 0.39, p < .001), which was reflective of a similar sex/gender profile in nonautistic individuals (SMD = 0.35, p < .001). Nonautistic males had significantly better social interaction and communication than males with ASD (SMD = 0.77, p < .001). Nonautistic females also had significantly better social interaction and communication than females with ASD (SMD = 0.72, p  <.001). Nonautistic males had better social interaction and communication than females with ASD, though this difference was not significant (SMD = 0.30, p = .07). CONCLUSIONS: This systematic review and meta-analysis highlighted important sex/gender differences in social interaction and communication for individuals with ASD, likely not captured by pre-existing diagnostic instruments, which potentially contribute to the under recognition of autism in females, and may need to be reflected in the diagnostic process. En ligne : http://dx.doi.org/10.1111/jcpp.13337 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456

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