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Auteur Tony CHARMAN |
Documents disponibles écrits par cet auteur (185)
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A prospective study of associations between early fearfulness and perceptual sensitivity and later restricted and repetitive behaviours in infants with typical and elevated likelihood of autism / Nisha NARVEKAR in Autism, 26-8 (November 2022)
[article]
Titre : A prospective study of associations between early fearfulness and perceptual sensitivity and later restricted and repetitive behaviours in infants with typical and elevated likelihood of autism Type de document : Texte imprimé et/ou numérique Auteurs : Nisha NARVEKAR, Auteur ; Virginia CARTER LENO, Auteur ; Greg PASCO, Auteur ; Mark H. JOHNSON, Auteur ; Emily J. H. JONES, Auteur ; Tony CHARMAN, Auteur Article en page(s) : p.1947-1958 Langues : Anglais (eng) Mots-clés : Child Infant Humans Autistic Disorder Stereotyped Behavior Prospective Studies Autism Spectrum Disorder Quality of Life Fear autism early development pathways elevated likelihood restricted and repetitive behaviours temperament to the research, authorship and/or publication of this article: T.C. has served as a paid consultant to F. Hoffmann-La Roche Ltd. and Servier, and has received royalties from Sage Publications and Guilford Publications. G.P. is a licensed ADOS-2 trainer and receives income from delivering ADOS-2 training. Index. décimale : PER Périodiques Résumé : Restricted interests and repetitive behaviours are central to the diagnosis of autism and can have profound effects on daily activities and quality of life. These challenges are also linked to other co-occurring conditions such as anxiety and sensory sensitivities. Here, we looked at whether early emerging signs of anxiety and sensory problems appear before symptoms of autism by studying infants with a family history of autism, as these infants are more likely to develop autism themselves. Studying infant siblings provides an opportunity for researchers to focus on early developmental markers of autism as these infants can be followed from birth. This study found that early infant signs of anxiety (e.g. fear/shyness) predicted later perceptual sensitivity, and those infants who scored higher on fear/shyness and sensitivity were more likely to experience more persistent repetitive behaviours, but also social and communication difficulties in toddlerhood. Early signs of anxiety and perceptual sensitivity may thus relate to both later social difficulties and repetitive behaviours. These findings support the importance of further research exploring the causal links between these domains in relation to autism, resulting in increased understanding of children who go onto develop autism in the future and guiding early interventions and supports. En ligne : http://dx.doi.org/10.1177/13623613211068932 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488
in Autism > 26-8 (November 2022) . - p.1947-1958[article] A prospective study of associations between early fearfulness and perceptual sensitivity and later restricted and repetitive behaviours in infants with typical and elevated likelihood of autism [Texte imprimé et/ou numérique] / Nisha NARVEKAR, Auteur ; Virginia CARTER LENO, Auteur ; Greg PASCO, Auteur ; Mark H. JOHNSON, Auteur ; Emily J. H. JONES, Auteur ; Tony CHARMAN, Auteur . - p.1947-1958.
Langues : Anglais (eng)
in Autism > 26-8 (November 2022) . - p.1947-1958
Mots-clés : Child Infant Humans Autistic Disorder Stereotyped Behavior Prospective Studies Autism Spectrum Disorder Quality of Life Fear autism early development pathways elevated likelihood restricted and repetitive behaviours temperament to the research, authorship and/or publication of this article: T.C. has served as a paid consultant to F. Hoffmann-La Roche Ltd. and Servier, and has received royalties from Sage Publications and Guilford Publications. G.P. is a licensed ADOS-2 trainer and receives income from delivering ADOS-2 training. Index. décimale : PER Périodiques Résumé : Restricted interests and repetitive behaviours are central to the diagnosis of autism and can have profound effects on daily activities and quality of life. These challenges are also linked to other co-occurring conditions such as anxiety and sensory sensitivities. Here, we looked at whether early emerging signs of anxiety and sensory problems appear before symptoms of autism by studying infants with a family history of autism, as these infants are more likely to develop autism themselves. Studying infant siblings provides an opportunity for researchers to focus on early developmental markers of autism as these infants can be followed from birth. This study found that early infant signs of anxiety (e.g. fear/shyness) predicted later perceptual sensitivity, and those infants who scored higher on fear/shyness and sensitivity were more likely to experience more persistent repetitive behaviours, but also social and communication difficulties in toddlerhood. Early signs of anxiety and perceptual sensitivity may thus relate to both later social difficulties and repetitive behaviours. These findings support the importance of further research exploring the causal links between these domains in relation to autism, resulting in increased understanding of children who go onto develop autism in the future and guiding early interventions and supports. En ligne : http://dx.doi.org/10.1177/13623613211068932 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=488 Quality of interaction between at-risk infants and caregiver at 12–15 months is associated with 3-year autism outcome / Ming Wai WAN in Journal of Child Psychology and Psychiatry, 54-7 (July 2013)
[article]
Titre : Quality of interaction between at-risk infants and caregiver at 12–15 months is associated with 3-year autism outcome Type de document : Texte imprimé et/ou numérique Auteurs : Ming Wai WAN, Auteur ; Jonathan GREEN, Auteur ; Mayada ELSABBAGH, Auteur ; Mark H. JOHNSON, Auteur ; Tony CHARMAN, Auteur ; Faye PLUMMER, Auteur ; Basis Team THE, Auteur Article en page(s) : p.763-771 Langues : Anglais (eng) Mots-clés : ASD siblings mother–child relations high-risk infants parent sensitivity Index. décimale : PER Périodiques Résumé : Background: Recent models of the early emergence of autism spectrum disorder (ASD) propose that infant intrinsic risk susceptibilities in behaviour may be amplified by interaction within the early social environment into an increasingly atypical developmental trajectory. This study examines whether 6- and 12-month parent–infant interactions in at-risk siblings differ from those with low-risk and whether – in at-risk siblings – such interactions predict later 3-year classification of ASD or no ASD. Method: Within the British Autism Study of Infant Siblings (BASIS), 6-min videotaped episodes of parent–infant free play in infants at 6–10 months (45 at-risk siblings and 47 low-risk siblings) and 12–15 months (43 at-risk siblings and 48 low-risk siblings) in a laboratory setting were rated on the Manchester Assessment of Caregiver-Infant Interaction (MACI), blind to participant information. Standard tests were administered for concurrent behavioural signs of ASD features and developmental level. Systematic consensus diagnostic classification of ASD was made at 3 years for the at-risk siblings. Results: Parent nondirectiveness and sensitive responsiveness differed in relation to ASD/risk status (at-risk ASD, at-risk no-ASD and low-risk) at both 6 and 12 months. At 6 months, infant liveliness was lower in the at-risk groups; at 12 months, infant attentiveness to parent and positive affect were lower in the at-risk group later diagnosed with ASD. Dyadic mutuality and intensity of engagement showed a group effect at 12 months. Dyadic mutuality, infant positive affect and infant attentiveness to parent at 12 months (but not 6 months) predicted 3-year ASD outcome, whereas infant ASD-related behavioural atypicality did not. Conclusions: This is the first prospective evidence that early dyadic interaction between at-risk infants and their parents is associated with later diagnostic outcome in ASD. Possible explanations for these findings and their theoretical implications are considered. En ligne : http://dx.doi.org/10.1111/jcpp.12032 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=203
in Journal of Child Psychology and Psychiatry > 54-7 (July 2013) . - p.763-771[article] Quality of interaction between at-risk infants and caregiver at 12–15 months is associated with 3-year autism outcome [Texte imprimé et/ou numérique] / Ming Wai WAN, Auteur ; Jonathan GREEN, Auteur ; Mayada ELSABBAGH, Auteur ; Mark H. JOHNSON, Auteur ; Tony CHARMAN, Auteur ; Faye PLUMMER, Auteur ; Basis Team THE, Auteur . - p.763-771.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 54-7 (July 2013) . - p.763-771
Mots-clés : ASD siblings mother–child relations high-risk infants parent sensitivity Index. décimale : PER Périodiques Résumé : Background: Recent models of the early emergence of autism spectrum disorder (ASD) propose that infant intrinsic risk susceptibilities in behaviour may be amplified by interaction within the early social environment into an increasingly atypical developmental trajectory. This study examines whether 6- and 12-month parent–infant interactions in at-risk siblings differ from those with low-risk and whether – in at-risk siblings – such interactions predict later 3-year classification of ASD or no ASD. Method: Within the British Autism Study of Infant Siblings (BASIS), 6-min videotaped episodes of parent–infant free play in infants at 6–10 months (45 at-risk siblings and 47 low-risk siblings) and 12–15 months (43 at-risk siblings and 48 low-risk siblings) in a laboratory setting were rated on the Manchester Assessment of Caregiver-Infant Interaction (MACI), blind to participant information. Standard tests were administered for concurrent behavioural signs of ASD features and developmental level. Systematic consensus diagnostic classification of ASD was made at 3 years for the at-risk siblings. Results: Parent nondirectiveness and sensitive responsiveness differed in relation to ASD/risk status (at-risk ASD, at-risk no-ASD and low-risk) at both 6 and 12 months. At 6 months, infant liveliness was lower in the at-risk groups; at 12 months, infant attentiveness to parent and positive affect were lower in the at-risk group later diagnosed with ASD. Dyadic mutuality and intensity of engagement showed a group effect at 12 months. Dyadic mutuality, infant positive affect and infant attentiveness to parent at 12 months (but not 6 months) predicted 3-year ASD outcome, whereas infant ASD-related behavioural atypicality did not. Conclusions: This is the first prospective evidence that early dyadic interaction between at-risk infants and their parents is associated with later diagnostic outcome in ASD. Possible explanations for these findings and their theoretical implications are considered. En ligne : http://dx.doi.org/10.1111/jcpp.12032 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=203 Randomised trial of a parent-mediated intervention for infants at high risk for autism: longitudinal outcomes to age 3 years / Jonathan GREEN in Journal of Child Psychology and Psychiatry, 58-12 (December 2017)
[article]
Titre : Randomised trial of a parent-mediated intervention for infants at high risk for autism: longitudinal outcomes to age 3 years Type de document : Texte imprimé et/ou numérique Auteurs : Jonathan GREEN, Auteur ; Andrew PICKLES, Auteur ; Greg PASCO, Auteur ; Rachael BEDFORD, Auteur ; Ming Wai WAN, Auteur ; Mayada ELSABBAGH, Auteur ; Vicky SLONIMS, Auteur ; Teea GLIGA, Auteur ; Emily JONES, Auteur ; Celeste H.M. CHEUNG, Auteur ; Tony CHARMAN, Auteur ; Mark H. JOHNSON, Auteur ; Team THE BRITISH AUTISM STUDY OF INFANT SIBLINGS, Auteur Article en page(s) : p.1330-1340 Langues : Anglais (eng) Mots-clés : Pre-emptive intervention prevention trials autism autism spectrum disorder high-risk siblings parent-mediated intervention Index. décimale : PER Périodiques Résumé : Background There has been increasing interest in the potential for pre-emptive interventions in the prodrome of autism, but little investigation as to their effect. Methods A two-site, two-arm assessor-blinded randomised controlled trial (RCT) of a 12-session parent-mediated social communication intervention delivered between 9 and 14 months of age (Intervention in the British Autism Study of Infant Siblings-Video Interaction for Promoting Positive Parenting), against no intervention. Fifty-four infants (28 intervention, 26 nonintervention) at familial risk of autism but not otherwise selected for developmental atypicality were assessed at 9-month baseline, 15-month treatment endpoint, and 27- and 39-month follow-up. Primary outcome: severity of autism prodromal symptoms, blind-rated on Autism Observation Schedule for Infants or Autism Diagnostic Observation Schedule 2nd Edition across the four assessment points. Secondary outcomes: blind-rated parent–child interaction and child language; nonblind parent-rated communication and socialisation. Prespecified intention-to-treat analysis combined estimates from repeated measures within correlated regressions to estimate the overall effect of the infancy intervention over time. Results Effect estimates in favour of intervention on autism prodromal symptoms, maximal at 27 months, had confidence intervals (CIs) at each separate time point including the null, but showed a significant overall effect over the course of the intervention and follow-up period (effect size [ES] = 0.32; 95% CI 0.04, 0.60; p = .026). Effects on proximal intervention targets of parent nondirectiveness/synchrony (ES = 0.33; CI 0.04, 0.63; p = .013) and child attentiveness/communication initiation (ES = 0.36; 95% CI 0.04, 0.68; p = .015) showed similar results. There was no effect on categorical diagnostic outcome or formal language measures. Conclusions Follow-up to 3 years of the first RCT of a very early social communication intervention for infants at familial risk of developing autism has shown a treatment effect, extending 24 months after intervention end, to reduce the overall severity of autism prodromal symptoms and enhance parent–child dyadic social communication over this period. We highlight the value of extended follow-up and repeat assessment for early intervention trials. En ligne : http://dx.doi.org/10.1111/jcpp.12728 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=326
in Journal of Child Psychology and Psychiatry > 58-12 (December 2017) . - p.1330-1340[article] Randomised trial of a parent-mediated intervention for infants at high risk for autism: longitudinal outcomes to age 3 years [Texte imprimé et/ou numérique] / Jonathan GREEN, Auteur ; Andrew PICKLES, Auteur ; Greg PASCO, Auteur ; Rachael BEDFORD, Auteur ; Ming Wai WAN, Auteur ; Mayada ELSABBAGH, Auteur ; Vicky SLONIMS, Auteur ; Teea GLIGA, Auteur ; Emily JONES, Auteur ; Celeste H.M. CHEUNG, Auteur ; Tony CHARMAN, Auteur ; Mark H. JOHNSON, Auteur ; Team THE BRITISH AUTISM STUDY OF INFANT SIBLINGS, Auteur . - p.1330-1340.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 58-12 (December 2017) . - p.1330-1340
Mots-clés : Pre-emptive intervention prevention trials autism autism spectrum disorder high-risk siblings parent-mediated intervention Index. décimale : PER Périodiques Résumé : Background There has been increasing interest in the potential for pre-emptive interventions in the prodrome of autism, but little investigation as to their effect. Methods A two-site, two-arm assessor-blinded randomised controlled trial (RCT) of a 12-session parent-mediated social communication intervention delivered between 9 and 14 months of age (Intervention in the British Autism Study of Infant Siblings-Video Interaction for Promoting Positive Parenting), against no intervention. Fifty-four infants (28 intervention, 26 nonintervention) at familial risk of autism but not otherwise selected for developmental atypicality were assessed at 9-month baseline, 15-month treatment endpoint, and 27- and 39-month follow-up. Primary outcome: severity of autism prodromal symptoms, blind-rated on Autism Observation Schedule for Infants or Autism Diagnostic Observation Schedule 2nd Edition across the four assessment points. Secondary outcomes: blind-rated parent–child interaction and child language; nonblind parent-rated communication and socialisation. Prespecified intention-to-treat analysis combined estimates from repeated measures within correlated regressions to estimate the overall effect of the infancy intervention over time. Results Effect estimates in favour of intervention on autism prodromal symptoms, maximal at 27 months, had confidence intervals (CIs) at each separate time point including the null, but showed a significant overall effect over the course of the intervention and follow-up period (effect size [ES] = 0.32; 95% CI 0.04, 0.60; p = .026). Effects on proximal intervention targets of parent nondirectiveness/synchrony (ES = 0.33; CI 0.04, 0.63; p = .013) and child attentiveness/communication initiation (ES = 0.36; 95% CI 0.04, 0.68; p = .015) showed similar results. There was no effect on categorical diagnostic outcome or formal language measures. Conclusions Follow-up to 3 years of the first RCT of a very early social communication intervention for infants at familial risk of developing autism has shown a treatment effect, extending 24 months after intervention end, to reduce the overall severity of autism prodromal symptoms and enhance parent–child dyadic social communication over this period. We highlight the value of extended follow-up and repeat assessment for early intervention trials. En ligne : http://dx.doi.org/10.1111/jcpp.12728 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=326 Reactions to Ostracism in Adolescents with Autism Spectrum Conditions / Catherine L. SEBASTIAN in Journal of Autism and Developmental Disorders, 39-8 (August 2009)
[article]
Titre : Reactions to Ostracism in Adolescents with Autism Spectrum Conditions Type de document : Texte imprimé et/ou numérique Auteurs : Catherine L. SEBASTIAN, Auteur ; Tony CHARMAN, Auteur ; Sarah-Jayne BLAKEMORE, Auteur Année de publication : 2009 Article en page(s) : p.1122-1130 Langues : Anglais (eng) Mots-clés : Autism-spectrum-conditions-(ASC) Ostracism Adolescence Self-report Index. décimale : PER Périodiques Résumé : Little is known about how adolescents with autism spectrum conditions (ASC) experience the initial impact of ostracism. This study investigated whether a mild, short-term episode of experimentally induced ostracism (Cyberball) would affect self-reported anxiety, mood, and the extent to which four social needs (self-esteem, belonging, control and meaningful existence) were threatened in adolescents with ASC and matched controls. Anxiety and the four needs were negatively affected by ostracism in both groups. However, ostracism did not modulate mood in the ASC group, and a number of possible interpretations of this group difference are discussed. In general, the results of this study suggest that normative models of ostracism are applicable to ASC. En ligne : http://dx.doi.org/10.1007/s10803-009-0725-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=788
in Journal of Autism and Developmental Disorders > 39-8 (August 2009) . - p.1122-1130[article] Reactions to Ostracism in Adolescents with Autism Spectrum Conditions [Texte imprimé et/ou numérique] / Catherine L. SEBASTIAN, Auteur ; Tony CHARMAN, Auteur ; Sarah-Jayne BLAKEMORE, Auteur . - 2009 . - p.1122-1130.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 39-8 (August 2009) . - p.1122-1130
Mots-clés : Autism-spectrum-conditions-(ASC) Ostracism Adolescence Self-report Index. décimale : PER Périodiques Résumé : Little is known about how adolescents with autism spectrum conditions (ASC) experience the initial impact of ostracism. This study investigated whether a mild, short-term episode of experimentally induced ostracism (Cyberball) would affect self-reported anxiety, mood, and the extent to which four social needs (self-esteem, belonging, control and meaningful existence) were threatened in adolescents with ASC and matched controls. Anxiety and the four needs were negatively affected by ostracism in both groups. However, ostracism did not modulate mood in the ASC group, and a number of possible interpretations of this group difference are discussed. In general, the results of this study suggest that normative models of ostracism are applicable to ASC. En ligne : http://dx.doi.org/10.1007/s10803-009-0725-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=788 Reading Comprehension in Autism Spectrum Disorders: The Role of Oral Language and Social Functioning / Jessie RICKETTS in Journal of Autism and Developmental Disorders, 43-4 (April 2013)
[article]
Titre : Reading Comprehension in Autism Spectrum Disorders: The Role of Oral Language and Social Functioning Type de document : Texte imprimé et/ou numérique Auteurs : Jessie RICKETTS, Auteur ; Catherine R. G. JONES, Auteur ; Francesca HAPPE, Auteur ; Tony CHARMAN, Auteur Article en page(s) : p.807-816 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders Reading comprehension Mentalising Oral language Index. décimale : PER Périodiques Résumé : Reading comprehension is an area of difficulty for many individuals with autism spectrum disorders (ASD). According to the Simple View of Reading, word recognition and oral language are both important determinants of reading comprehension ability. We provide a novel test of this model in 100 adolescents with ASD of varying intellectual ability. Further, we explore whether reading comprehension is additionally influenced by individual differences in social behaviour and social cognition in ASD. Adolescents with ASD aged 14–16 years completed assessments indexing word recognition, oral language, reading comprehension, social behaviour and social cognition. Regression analyses show that both word recognition and oral language explain unique variance in reading comprehension. Further, measures of social behaviour and social cognition predict reading comprehension after controlling for the variance explained by word recognition and oral language. This indicates that word recognition, oral language and social impairments may constrain reading comprehension in ASD. En ligne : http://dx.doi.org/10.1007/s10803-012-1619-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=194
in Journal of Autism and Developmental Disorders > 43-4 (April 2013) . - p.807-816[article] Reading Comprehension in Autism Spectrum Disorders: The Role of Oral Language and Social Functioning [Texte imprimé et/ou numérique] / Jessie RICKETTS, Auteur ; Catherine R. G. JONES, Auteur ; Francesca HAPPE, Auteur ; Tony CHARMAN, Auteur . - p.807-816.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 43-4 (April 2013) . - p.807-816
Mots-clés : Autism spectrum disorders Reading comprehension Mentalising Oral language Index. décimale : PER Périodiques Résumé : Reading comprehension is an area of difficulty for many individuals with autism spectrum disorders (ASD). According to the Simple View of Reading, word recognition and oral language are both important determinants of reading comprehension ability. We provide a novel test of this model in 100 adolescents with ASD of varying intellectual ability. Further, we explore whether reading comprehension is additionally influenced by individual differences in social behaviour and social cognition in ASD. Adolescents with ASD aged 14–16 years completed assessments indexing word recognition, oral language, reading comprehension, social behaviour and social cognition. Regression analyses show that both word recognition and oral language explain unique variance in reading comprehension. Further, measures of social behaviour and social cognition predict reading comprehension after controlling for the variance explained by word recognition and oral language. This indicates that word recognition, oral language and social impairments may constrain reading comprehension in ASD. En ligne : http://dx.doi.org/10.1007/s10803-012-1619-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=194 Real-World Experiences in Autistic Adult Diagnostic Services and Post-diagnostic Support and Alignment with Services Guidelines: Results from the ASDEU Study / M. L. SCATTONI in Journal of Autism and Developmental Disorders, 51-11 (November 2021)
PermalinkRecommandations additionnelles sur l'administration et la notation du CHAT / Peter DOEHRING
PermalinkRegression, Developmental Trajectory and Associated Problems in Disorders in the Autism Spectrum: The SNAP Study / Gillian BAIRD in Journal of Autism and Developmental Disorders, 38-10 (November 2008)
PermalinkRegression in autism spectrum disorder: Reconciling findings from retrospective and prospective research / N. PEARSON in Autism Research, 11-12 (December 2018)
PermalinkRepetitive Behaviors and Social-Communicative Impairments in Autism: Implications for Developmental Theory and Diagnosis / Tony CHARMAN
PermalinkResting state EEG power spectrum and functional connectivity in autism: a cross-sectional analysis / Pilar GARCES in Molecular Autism, 13 (2022)
PermalinkPermalinkSchool based cognitive behavioural therapy targeting anxiety in children with autistic spectrum disorder: a quasi-experimental randomised controlled trail incorporating a mixed methods approach / C. CLARKE in Journal of Autism and Developmental Disorders, 47-12 (December 2017)
PermalinkScreening for Autism Spectrum Disorders in Populations: Progress, Challenges, and Questions for Future Research and Practice / Tony CHARMAN
PermalinkSevere mood problems in adolescents with autism spectrum disorder / Emily SIMONOFF in Journal of Child Psychology and Psychiatry, 53-11 (November 2012)
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