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Détail de l'auteur
Auteur Antonio Y. HARDAN |
Documents disponibles écrits par cet auteur (28)
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A Two-Year Longitudinal MRI Study of the Corpus Callosum in Autism / Thomas W. FRAZIER in Journal of Autism and Developmental Disorders, 42-11 (November 2012)
[article]
Titre : A Two-Year Longitudinal MRI Study of the Corpus Callosum in Autism Type de document : Texte imprimé et/ou numérique Auteurs : Thomas W. FRAZIER, Auteur ; Matcheri S. KESHAVAN, Auteur ; Nancy J. MINSHEW, Auteur ; Antonio Y. HARDAN, Auteur Article en page(s) : p.2312-2322 Langues : Anglais (eng) Mots-clés : Magnetic resonance imaging Autism Corpus callosum Rostral body Index. décimale : PER Périodiques Résumé : A growing body of literature has identified size reductions of the corpus callosum (CC) in autism. However, to our knowledge, no published studies have reported on the growth of CC volumes in youth with autism. Volumes of the total CC and its sub-divisions were obtained from 23 male children with autism and 23 age- and gender-matched controls at baseline and 2-year follow-up. Persistent reductions in total CC volume were observed in participants with autism relative to controls. Only the rostral body subdivision showed a normalization of size over time. Persistent reductions are consistent with the diagnostic stability and life-long impairment observed in many individuals with autism. Multi-modal imaging studies are needed to identify specific fiber tracks contributing to CC reductions. En ligne : http://dx.doi.org/10.1007/s10803-012-1478-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=182
in Journal of Autism and Developmental Disorders > 42-11 (November 2012) . - p.2312-2322[article] A Two-Year Longitudinal MRI Study of the Corpus Callosum in Autism [Texte imprimé et/ou numérique] / Thomas W. FRAZIER, Auteur ; Matcheri S. KESHAVAN, Auteur ; Nancy J. MINSHEW, Auteur ; Antonio Y. HARDAN, Auteur . - p.2312-2322.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 42-11 (November 2012) . - p.2312-2322
Mots-clés : Magnetic resonance imaging Autism Corpus callosum Rostral body Index. décimale : PER Périodiques Résumé : A growing body of literature has identified size reductions of the corpus callosum (CC) in autism. However, to our knowledge, no published studies have reported on the growth of CC volumes in youth with autism. Volumes of the total CC and its sub-divisions were obtained from 23 male children with autism and 23 age- and gender-matched controls at baseline and 2-year follow-up. Persistent reductions in total CC volume were observed in participants with autism relative to controls. Only the rostral body subdivision showed a normalization of size over time. Persistent reductions are consistent with the diagnostic stability and life-long impairment observed in many individuals with autism. Multi-modal imaging studies are needed to identify specific fiber tracks contributing to CC reductions. En ligne : http://dx.doi.org/10.1007/s10803-012-1478-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=182 Understanding the heterogeneity of anxiety in autistic youth: A person-centered approach / Emily SPACKMAN in Autism Research, 15-9 (September 2022)
[article]
Titre : Understanding the heterogeneity of anxiety in autistic youth: A person-centered approach Type de document : Texte imprimé et/ou numérique Auteurs : Emily SPACKMAN, Auteur ; Jian Wei LERH, Auteur ; Jacqui RODGERS, Auteur ; Matthew J. HOLLOCKS, Auteur ; Mikle SOUTH, Auteur ; Helen MCCONACHIE, Auteur ; Ann OZSIVADJIAN, Auteur ; Amy VAUGHAN VAN HECKE, Auteur ; Robin LIBOVE, Auteur ; Antonio Y. HARDAN, Auteur ; Susan R. LEEKAM, Auteur ; Emily SIMONOFF, Auteur ; Thomas W. FRAZIER, Auteur ; Gail A. ALVARES, Auteur ; Jessica M. SCHWARTZMAN, Auteur ; Iliana MAGIATI, Auteur ; Mirko ULJAREVIĆ, Auteur Article en page(s) : p.1742-1754 Langues : Anglais (eng) Mots-clés : Adolescent Anxiety/complications/psychology Anxiety Disorders/psychology Autism Spectrum Disorder/complications/epidemiology/psychology Autistic Disorder Child Child Development Disorders, Pervasive Child, Preschool Female Humans anxiety autism individual differences latent profile analysis subtyping Index. décimale : PER Périodiques Résumé : The present study aimed to examine anxiety profiles among children and adolescents on the autism spectrum. It further aimed to characterize the association between the identified anxiety profiles and key clinical and developmental variables. The Spence Children's Anxiety Scale-Parent Version (SCAS-P) data from a large international pooled sample of 870 caregivers of autistic children and adolescents (M(age)  = 11.6years, SD(age)  = 2.77; 107 females) was used. Latent profile analysis identified a three-anxiety profile solution exhibiting high entropy (0.80) and high latent profile probabilities, with good classification accuracy. Identified profiles fell along the severity spectrum and were named as the mild (n = 498), moderate (n = 272) and severe (n= 100) anxiety profiles. There were no statistically significant differences between the three anxiety profiles in terms of sex distribution. Participants in the mild profile were significantly younger than those in the severe profile, had significantly fewer social communication difficulties than youth in the moderate anxiety profile group and had significantly fewer restricted and repetitive behaviors and lower cognitive functioning scores compared to participants in moderate and severe anxiety profiles. This is the first study to move beyond identifying associations and group-level differences to exploring and identifying characteristics of anxiety-based subgroups at an individual level that differ on key clinical and developmental variables. The subgroups identified in this study are a preliminary, yet important, first step towards informing future assessment and individualized interventions aiming to support young people on the autism spectrum to reduce and manage anxiety. LAY SUMMARY: This study tried to understand if there are subgroups of autistic young people who may have similar anxiety profiles. We found that we could meaningfully group young people into three groups based on how severe the anxiety symptoms their caregivers reported were: a group with low levels of anxiety, those with moderate anxiety, and those with more severe anxiety. We also found that the young people in the mild group were younger, had fewer autism traits and lower levels of intellectual functioning than young people in the other two groups. En ligne : http://dx.doi.org/10.1002/aur.2744 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=483
in Autism Research > 15-9 (September 2022) . - p.1742-1754[article] Understanding the heterogeneity of anxiety in autistic youth: A person-centered approach [Texte imprimé et/ou numérique] / Emily SPACKMAN, Auteur ; Jian Wei LERH, Auteur ; Jacqui RODGERS, Auteur ; Matthew J. HOLLOCKS, Auteur ; Mikle SOUTH, Auteur ; Helen MCCONACHIE, Auteur ; Ann OZSIVADJIAN, Auteur ; Amy VAUGHAN VAN HECKE, Auteur ; Robin LIBOVE, Auteur ; Antonio Y. HARDAN, Auteur ; Susan R. LEEKAM, Auteur ; Emily SIMONOFF, Auteur ; Thomas W. FRAZIER, Auteur ; Gail A. ALVARES, Auteur ; Jessica M. SCHWARTZMAN, Auteur ; Iliana MAGIATI, Auteur ; Mirko ULJAREVIĆ, Auteur . - p.1742-1754.
Langues : Anglais (eng)
in Autism Research > 15-9 (September 2022) . - p.1742-1754
Mots-clés : Adolescent Anxiety/complications/psychology Anxiety Disorders/psychology Autism Spectrum Disorder/complications/epidemiology/psychology Autistic Disorder Child Child Development Disorders, Pervasive Child, Preschool Female Humans anxiety autism individual differences latent profile analysis subtyping Index. décimale : PER Périodiques Résumé : The present study aimed to examine anxiety profiles among children and adolescents on the autism spectrum. It further aimed to characterize the association between the identified anxiety profiles and key clinical and developmental variables. The Spence Children's Anxiety Scale-Parent Version (SCAS-P) data from a large international pooled sample of 870 caregivers of autistic children and adolescents (M(age)  = 11.6years, SD(age)  = 2.77; 107 females) was used. Latent profile analysis identified a three-anxiety profile solution exhibiting high entropy (0.80) and high latent profile probabilities, with good classification accuracy. Identified profiles fell along the severity spectrum and were named as the mild (n = 498), moderate (n = 272) and severe (n= 100) anxiety profiles. There were no statistically significant differences between the three anxiety profiles in terms of sex distribution. Participants in the mild profile were significantly younger than those in the severe profile, had significantly fewer social communication difficulties than youth in the moderate anxiety profile group and had significantly fewer restricted and repetitive behaviors and lower cognitive functioning scores compared to participants in moderate and severe anxiety profiles. This is the first study to move beyond identifying associations and group-level differences to exploring and identifying characteristics of anxiety-based subgroups at an individual level that differ on key clinical and developmental variables. The subgroups identified in this study are a preliminary, yet important, first step towards informing future assessment and individualized interventions aiming to support young people on the autism spectrum to reduce and manage anxiety. LAY SUMMARY: This study tried to understand if there are subgroups of autistic young people who may have similar anxiety profiles. We found that we could meaningfully group young people into three groups based on how severe the anxiety symptoms their caregivers reported were: a group with low levels of anxiety, those with moderate anxiety, and those with more severe anxiety. We also found that the young people in the mild group were younger, had fewer autism traits and lower levels of intellectual functioning than young people in the other two groups. En ligne : http://dx.doi.org/10.1002/aur.2744 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=483 When Are Psychiatric Medications Used in the Treatment of ASC? / Wendy FROEHLICH
Titre : When Are Psychiatric Medications Used in the Treatment of ASC? Type de document : Texte imprimé et/ou numérique Auteurs : Wendy FROEHLICH, Auteur ; Linda J. LOTSPEICH, Auteur ; Antonio Y. HARDAN, Auteur Année de publication : 2011 Importance : p.207-210 Langues : Anglais (eng) Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=139 When Are Psychiatric Medications Used in the Treatment of ASC? [Texte imprimé et/ou numérique] / Wendy FROEHLICH, Auteur ; Linda J. LOTSPEICH, Auteur ; Antonio Y. HARDAN, Auteur . - 2011 . - p.207-210.
Langues : Anglais (eng)
Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=139 Exemplaires
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