
- <Centre d'Information et de documentation du CRA Rhône-Alpes
- CRA
- Informations pratiques
-
Adresse
Centre d'information et de documentation
Horaires
du CRA Rhône-Alpes
Centre Hospitalier le Vinatier
bât 211
95, Bd Pinel
69678 Bron CedexLundi au Vendredi
Contact
9h00-12h00 13h30-16h00Tél: +33(0)4 37 91 54 65
Mail
Fax: +33(0)4 37 91 54 37
-
Adresse
Mention de date : July 2018
Paru le : 01/07/2018 |
[n° ou bulletin]
[n° ou bulletin]
59-7 - July 2018 [Texte imprimé et/ou numérique] . - 2018. Langues : Anglais (eng)
|
Exemplaires (1)
Code-barres | Cote | Support | Localisation | Section | Disponibilité |
---|---|---|---|---|---|
PER0001645 | PER JCP | Périodique | Centre d'Information et de Documentation du CRA Rhône-Alpes | PER - Périodiques | Exclu du prêt |
Dépouillements


Editorial: The rising prevalence of autism / E. FOMBONNE in Journal of Child Psychology and Psychiatry, 59-7 (July 2018)
![]()
[article]
Titre : Editorial: The rising prevalence of autism Type de document : Texte imprimé et/ou numérique Auteurs : E. FOMBONNE, Auteur Article en page(s) : p.717-720 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The first autism surveys were simple head counts of children already diagnosed with a severe autism phenotype and residing in small, circumscribed geographical areas. Prevalence was low, ranging from 0.4 to 2/1,000 in the 1960's and 1970's. Today, the methodology of surveys has become more complex; studies include large populations, multiple sites, stratified samples and rely on intricate sets of screening activities followed by some form of diagnostic confirmation procedures. Yet, and as surprising as it may be, there is no standardization of autism survey methodology. Each survey has unique design features that reflect the local educational and health services infrastructure and current social policies for children with disabilities, they include or not parents, teachers and subjects with Autism Spectrum Disorder (ASD), and rely on variable screening and diagnostic instruments and methods. As such, prevalence differences between studies are hazardous to evaluate and whether observed discrepancies are due to method factors or true differences in population parameters, cannot be determined. En ligne : http://dx.doi.org/10.1111/jcpp.12941 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368
in Journal of Child Psychology and Psychiatry > 59-7 (July 2018) . - p.717-720[article] Editorial: The rising prevalence of autism [Texte imprimé et/ou numérique] / E. FOMBONNE, Auteur . - p.717-720.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 59-7 (July 2018) . - p.717-720
Index. décimale : PER Périodiques Résumé : The first autism surveys were simple head counts of children already diagnosed with a severe autism phenotype and residing in small, circumscribed geographical areas. Prevalence was low, ranging from 0.4 to 2/1,000 in the 1960's and 1970's. Today, the methodology of surveys has become more complex; studies include large populations, multiple sites, stratified samples and rely on intricate sets of screening activities followed by some form of diagnostic confirmation procedures. Yet, and as surprising as it may be, there is no standardization of autism survey methodology. Each survey has unique design features that reflect the local educational and health services infrastructure and current social policies for children with disabilities, they include or not parents, teachers and subjects with Autism Spectrum Disorder (ASD), and rely on variable screening and diagnostic instruments and methods. As such, prevalence differences between studies are hazardous to evaluate and whether observed discrepancies are due to method factors or true differences in population parameters, cannot be determined. En ligne : http://dx.doi.org/10.1111/jcpp.12941 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368 Practitioner Review: Definition, recognition, and treatment challenges of irritability in young people / A. STRINGARIS in Journal of Child Psychology and Psychiatry, 59-7 (July 2018)
![]()
[article]
Titre : Practitioner Review: Definition, recognition, and treatment challenges of irritability in young people Type de document : Texte imprimé et/ou numérique Auteurs : A. STRINGARIS, Auteur ; P. VIDAL-RIBAS, Auteur ; Melissa A. BROTMAN, Auteur ; E. LEIBENLUFT, Auteur Article en page(s) : p.721-739 Langues : Anglais (eng) Mots-clés : Emotional dysregulation assessment intervention mood disorder temper tantrums Index. décimale : PER Périodiques Résumé : BACKGROUND: Irritability is one of the most common reasons for referral to child and adolescent mental health services and is the main characteristic of the new diagnosis of disruptive mood dysregulation disorder (DMDD). However, the recognition and management of irritability presents a major challenge in clinical practice and may be partly responsible for the dramatic increase in antipsychotic prescribing in recent years. METHODS: In this review, we provide up-to-date information on the definition and mechanisms underlying irritability, and its assessment in clinical practice. We aim to discuss the latest research on DMDD, and the presence of severe irritability in the context of other disorders, as well as to recommend a treatment algorithm. RESULTS: Severe irritability is associated with aberrant reward processing and bias toward threatening stimuli. Several measures are available to easily assess irritability. The recent diagnosis of DMDD captures children whose main problem is severe irritability and differ from those with bipolar disorder in longitudinal outcomes, family history, and behavioral and neural correlates. Treatment of irritability might depend on the context it appears. Indirect evidence suggests that parent management training (PMT) and cognitive behavioral therapy (CBT) are the most supported psychological treatments for irritability. CONCLUSIONS: Irritability, recognized as a mood problem rather than a purely behavioral manifestation, is a common condition for young people. Practitioners should not ignore irritability as it is associated with substantial morbidity and impairment. Although there are no trials with irritability as main outcome, clinicians can apply several existing pharmacological and psychological interventions for its treatment. Also, new promising approaches relying on pathophysiological findings, such as exposure-based cognitive behavioral therapy techniques and interpretation bias training (IBT), are being currently investigated. En ligne : http://dx.doi.org/10.1111/jcpp.12823 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368
in Journal of Child Psychology and Psychiatry > 59-7 (July 2018) . - p.721-739[article] Practitioner Review: Definition, recognition, and treatment challenges of irritability in young people [Texte imprimé et/ou numérique] / A. STRINGARIS, Auteur ; P. VIDAL-RIBAS, Auteur ; Melissa A. BROTMAN, Auteur ; E. LEIBENLUFT, Auteur . - p.721-739.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 59-7 (July 2018) . - p.721-739
Mots-clés : Emotional dysregulation assessment intervention mood disorder temper tantrums Index. décimale : PER Périodiques Résumé : BACKGROUND: Irritability is one of the most common reasons for referral to child and adolescent mental health services and is the main characteristic of the new diagnosis of disruptive mood dysregulation disorder (DMDD). However, the recognition and management of irritability presents a major challenge in clinical practice and may be partly responsible for the dramatic increase in antipsychotic prescribing in recent years. METHODS: In this review, we provide up-to-date information on the definition and mechanisms underlying irritability, and its assessment in clinical practice. We aim to discuss the latest research on DMDD, and the presence of severe irritability in the context of other disorders, as well as to recommend a treatment algorithm. RESULTS: Severe irritability is associated with aberrant reward processing and bias toward threatening stimuli. Several measures are available to easily assess irritability. The recent diagnosis of DMDD captures children whose main problem is severe irritability and differ from those with bipolar disorder in longitudinal outcomes, family history, and behavioral and neural correlates. Treatment of irritability might depend on the context it appears. Indirect evidence suggests that parent management training (PMT) and cognitive behavioral therapy (CBT) are the most supported psychological treatments for irritability. CONCLUSIONS: Irritability, recognized as a mood problem rather than a purely behavioral manifestation, is a common condition for young people. Practitioners should not ignore irritability as it is associated with substantial morbidity and impairment. Although there are no trials with irritability as main outcome, clinicians can apply several existing pharmacological and psychological interventions for its treatment. Also, new promising approaches relying on pathophysiological findings, such as exposure-based cognitive behavioral therapy techniques and interpretation bias training (IBT), are being currently investigated. En ligne : http://dx.doi.org/10.1111/jcpp.12823 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368 Commentary: Frying pan to fire? Commentary on Stringaris et al. (2018) / Gabrielle A. CARLSON in Journal of Child Psychology and Psychiatry, 59-7 (July 2018)
![]()
[article]
Titre : Commentary: Frying pan to fire? Commentary on Stringaris et al. (2018) Type de document : Texte imprimé et/ou numérique Auteurs : Gabrielle A. CARLSON, Auteur ; D. N. KLEIN, Auteur Article en page(s) : p.740-743 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The bipolar disorder diagnosis in prepubertal children became popular because it answered a clinical need to treat the explosive behavior component of irritability and the hope that antimanic strategies would be helpful. Poor definition of episodes resulted in mixing chronic and episodic irritability in samples of children with bipolar disorder. The subsequent dramatic increase in neuroleptic use is a testimony to the importance of the problem of irritability and our need to better understand it. Insofar as our use of the term irritability conflates proneness to anger with the subsequent aggressive response, it will again not be clear who is being studied. We need to uncouple the mood and behavior aspects of irritability for further study or we will have traded the imprecision of "bipolar" for the imprecision of irritability. En ligne : http://dx.doi.org/10.1111/jcpp.12873 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368
in Journal of Child Psychology and Psychiatry > 59-7 (July 2018) . - p.740-743[article] Commentary: Frying pan to fire? Commentary on Stringaris et al. (2018) [Texte imprimé et/ou numérique] / Gabrielle A. CARLSON, Auteur ; D. N. KLEIN, Auteur . - p.740-743.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 59-7 (July 2018) . - p.740-743
Index. décimale : PER Périodiques Résumé : The bipolar disorder diagnosis in prepubertal children became popular because it answered a clinical need to treat the explosive behavior component of irritability and the hope that antimanic strategies would be helpful. Poor definition of episodes resulted in mixing chronic and episodic irritability in samples of children with bipolar disorder. The subsequent dramatic increase in neuroleptic use is a testimony to the importance of the problem of irritability and our need to better understand it. Insofar as our use of the term irritability conflates proneness to anger with the subsequent aggressive response, it will again not be clear who is being studied. We need to uncouple the mood and behavior aspects of irritability for further study or we will have traded the imprecision of "bipolar" for the imprecision of irritability. En ligne : http://dx.doi.org/10.1111/jcpp.12873 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368 Secular changes in the symptom level of clinically diagnosed autism / O. ARVIDSSON in Journal of Child Psychology and Psychiatry, 59-7 (July 2018)
![]()
[article]
Titre : Secular changes in the symptom level of clinically diagnosed autism Type de document : Texte imprimé et/ou numérique Auteurs : O. ARVIDSSON, Auteur ; C. GILLBERG, Auteur ; P. LICHTENSTEIN, Auteur ; S. LUNDSTRÖM, Auteur Article en page(s) : p.744-751 Langues : Anglais (eng) Mots-clés : Neurodevelopmental disorders autism spectrum disorders prevalence Index. décimale : PER Périodiques Résumé : BACKGROUND: The prevalence of autism has been reported to have increased worldwide. A decrease over time in the number of autism symptoms required for a clinical autism diagnosis would partly help explain this increase. This study aimed to determine whether the symptom level of clinically diagnosed autism cases below age 13 had changed over time. METHODS: Parents of Swedish 9-year old twins (n = 28,118) participated in a telephone survey, in which symptoms and dysfunction/suffering related to neurodevelopmental disorders [including autism, but also attention-deficit/hyperactivity disorder (ADHD), Developmental Coordination Disorder (DCD), and Learning Disabilities (LD)] in their children were assessed over a 10-year period. Survey data was merged with the National Patient Register containing clinically registered autism diagnoses (n = 271). RESULTS: In individuals who had been clinically diagnosed with autism before the age of 13, the symptom score for autism decreased on average 30% over more than a decade in birth cohorts 1992-2002. There was an average decrease of 50% in the autism symptom score from 2004 to 2014 in individuals who were diagnosed with autism at ages 7-12, but there was no decrease in those diagnosed at ages 0-6. CONCLUSIONS: Over time, considerably fewer autism symptoms seemed to be required for a clinical diagnosis of autism, at least for those diagnosed after the preschool years. The findings add support for the notion that the observed increase in autism diagnoses is, at least partly, the by-product of changes in clinical practice, and flag up the need for working in agreement with best practice guidelines. En ligne : http://dx.doi.org/10.1111/jcpp.12864 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368
in Journal of Child Psychology and Psychiatry > 59-7 (July 2018) . - p.744-751[article] Secular changes in the symptom level of clinically diagnosed autism [Texte imprimé et/ou numérique] / O. ARVIDSSON, Auteur ; C. GILLBERG, Auteur ; P. LICHTENSTEIN, Auteur ; S. LUNDSTRÖM, Auteur . - p.744-751.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 59-7 (July 2018) . - p.744-751
Mots-clés : Neurodevelopmental disorders autism spectrum disorders prevalence Index. décimale : PER Périodiques Résumé : BACKGROUND: The prevalence of autism has been reported to have increased worldwide. A decrease over time in the number of autism symptoms required for a clinical autism diagnosis would partly help explain this increase. This study aimed to determine whether the symptom level of clinically diagnosed autism cases below age 13 had changed over time. METHODS: Parents of Swedish 9-year old twins (n = 28,118) participated in a telephone survey, in which symptoms and dysfunction/suffering related to neurodevelopmental disorders [including autism, but also attention-deficit/hyperactivity disorder (ADHD), Developmental Coordination Disorder (DCD), and Learning Disabilities (LD)] in their children were assessed over a 10-year period. Survey data was merged with the National Patient Register containing clinically registered autism diagnoses (n = 271). RESULTS: In individuals who had been clinically diagnosed with autism before the age of 13, the symptom score for autism decreased on average 30% over more than a decade in birth cohorts 1992-2002. There was an average decrease of 50% in the autism symptom score from 2004 to 2014 in individuals who were diagnosed with autism at ages 7-12, but there was no decrease in those diagnosed at ages 0-6. CONCLUSIONS: Over time, considerably fewer autism symptoms seemed to be required for a clinical diagnosis of autism, at least for those diagnosed after the preschool years. The findings add support for the notion that the observed increase in autism diagnoses is, at least partly, the by-product of changes in clinical practice, and flag up the need for working in agreement with best practice guidelines. En ligne : http://dx.doi.org/10.1111/jcpp.12864 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368 A longitudinal functional magnetic resonance imaging study of task control circuits and bulimic symptoms over adolescence / M. CYR in Journal of Child Psychology and Psychiatry, 59-7 (July 2018)
![]()
[article]
Titre : A longitudinal functional magnetic resonance imaging study of task control circuits and bulimic symptoms over adolescence Type de document : Texte imprimé et/ou numérique Auteurs : M. CYR, Auteur ; M. FONTAINE, Auteur ; M. STEFAN, Auteur ; K. TERRANOVA, Auteur ; D. C. KOPALA-SIBLEY, Auteur ; E. ATTIA, Auteur ; R. MARSH, Auteur Article en page(s) : p.752-762 Langues : Anglais (eng) Mots-clés : Bulimia Nervosa adolescence functional magnetic resonance images longitudinal studies self-control Index. décimale : PER Périodiques Résumé : BACKGROUND: Previous cross-sectional findings from adolescents and adults with Bulimia Nervosa (BN) suggest disturbances in fronto-striatal and cingulo-opercular task control circuits that support self-regulatory processes, including the resolution of cognitive conflict. Herein, we used longitudinal data to examine the developmental trajectories of such disturbances and how the functioning of these circuits relates to changes in BN symptoms over adolescence. METHODS: Thirty-two adolescent females with BN symptoms and 28 healthy control (HC) adolescents participated in the study. Functional magnetic resonance images (fMRI) during performance of a Simon task were acquired at three time points within 2-year intervals over adolescence. From the initial sample, 70% and 30% of the participants completed the second and third time points, respectively. Participants who completed all study time points did not differ from those lost to attrition on baseline demographic characteristics or any outcome measures. Using a region-of-interest approach, growth curve models tested group differences in the trajectory of conflict-related activation in task control circuits over time. Cross-lagged panel models examined transactional relationships between conflict-related activation in the same regions and BN symptoms over time. RESULTS: Growth curve models revealed different trajectories of conflict-related activation in right task control regions across BN and HC adolescents, such that HC but not BN adolescents showed activation decreases over time. These group differences were greatest when including only the BN adolescents whose symptoms remitted over time. Cross-lagged panel models revealed that less frequent bulimic episodes at first follow-up predicted later increases in conflict-related activation in bilateral task control regions. CONCLUSIONS: These longitudinal findings suggest overengagement of task control circuits in BN adolescents, especially those most resilient to persistent illness. Such overengagement may compensate for regulatory disturbances, allowing them to regulate eating behaviors over development. Thus, task control circuits may constitute targets for early interventions that enhance self-regulatory control. En ligne : http://dx.doi.org/10.1111/jcpp.12840 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368
in Journal of Child Psychology and Psychiatry > 59-7 (July 2018) . - p.752-762[article] A longitudinal functional magnetic resonance imaging study of task control circuits and bulimic symptoms over adolescence [Texte imprimé et/ou numérique] / M. CYR, Auteur ; M. FONTAINE, Auteur ; M. STEFAN, Auteur ; K. TERRANOVA, Auteur ; D. C. KOPALA-SIBLEY, Auteur ; E. ATTIA, Auteur ; R. MARSH, Auteur . - p.752-762.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 59-7 (July 2018) . - p.752-762
Mots-clés : Bulimia Nervosa adolescence functional magnetic resonance images longitudinal studies self-control Index. décimale : PER Périodiques Résumé : BACKGROUND: Previous cross-sectional findings from adolescents and adults with Bulimia Nervosa (BN) suggest disturbances in fronto-striatal and cingulo-opercular task control circuits that support self-regulatory processes, including the resolution of cognitive conflict. Herein, we used longitudinal data to examine the developmental trajectories of such disturbances and how the functioning of these circuits relates to changes in BN symptoms over adolescence. METHODS: Thirty-two adolescent females with BN symptoms and 28 healthy control (HC) adolescents participated in the study. Functional magnetic resonance images (fMRI) during performance of a Simon task were acquired at three time points within 2-year intervals over adolescence. From the initial sample, 70% and 30% of the participants completed the second and third time points, respectively. Participants who completed all study time points did not differ from those lost to attrition on baseline demographic characteristics or any outcome measures. Using a region-of-interest approach, growth curve models tested group differences in the trajectory of conflict-related activation in task control circuits over time. Cross-lagged panel models examined transactional relationships between conflict-related activation in the same regions and BN symptoms over time. RESULTS: Growth curve models revealed different trajectories of conflict-related activation in right task control regions across BN and HC adolescents, such that HC but not BN adolescents showed activation decreases over time. These group differences were greatest when including only the BN adolescents whose symptoms remitted over time. Cross-lagged panel models revealed that less frequent bulimic episodes at first follow-up predicted later increases in conflict-related activation in bilateral task control regions. CONCLUSIONS: These longitudinal findings suggest overengagement of task control circuits in BN adolescents, especially those most resilient to persistent illness. Such overengagement may compensate for regulatory disturbances, allowing them to regulate eating behaviors over development. Thus, task control circuits may constitute targets for early interventions that enhance self-regulatory control. En ligne : http://dx.doi.org/10.1111/jcpp.12840 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368 The impact of treatment delivery format on response to cognitive behaviour therapy for preadolescent children with anxiety disorders / A. MCKINNON in Journal of Child Psychology and Psychiatry, 59-7 (July 2018)
![]()
[article]
Titre : The impact of treatment delivery format on response to cognitive behaviour therapy for preadolescent children with anxiety disorders Type de document : Texte imprimé et/ou numérique Auteurs : A. MCKINNON, Auteur ; R. KEERS, Auteur ; J. R. I. COLEMAN, Auteur ; K. J. LESTER, Auteur ; S. ROBERTS, Auteur ; Kristian ARENDT, Auteur ; Susan M. BOGELS, Auteur ; Peter COOPER, Auteur ; C. CRESWELL, Auteur ; Catharina A. HARTMAN, Auteur ; K. W. FJERMESTAD, Auteur ; T. IN-ALBON, Auteur ; K. LAVALLEE, Auteur ; H. J. LYNEHAM, Auteur ; P. SMITH, Auteur ; R. MEISER-STEDMAN, Auteur ; M. H. NAUTA, Auteur ; R. M. RAPEE, Auteur ; Y. REY, Auteur ; S. SCHNEIDER, Auteur ; W. K. SILVERMAN, Auteur ; M. THASTUM, Auteur ; K. THIRLWALL, Auteur ; Gro Janne WERGELAND, Auteur ; T. C. ELEY, Auteur ; J. L. HUDSON, Auteur Année de publication : 2018 Article en page(s) : p.763-772 Langues : Anglais (eng) Mots-clés : Anxiety cognitive therapy treatment trials Index. décimale : PER Périodiques Résumé : BACKGROUND: Several delivery formats of cognitive behaviour therapy (CBT) for child anxiety have been proposed, however, there is little consensus on the optimal delivery format. The primary goal of this study was to investigate the impact of the child's primary anxiety diagnosis on changes in clinical severity (of the primary problem) during individual CBT, group CBT and guided parent-led CBT. The secondary goal was to investigate the impact of the child's primary anxiety diagnosis on rates of remission for the three treatment formats. METHODS: A sample of 1,253 children (5-12 years; Mage = 9.3, SD = 1.7) was pooled from CBT trials carried out at 10 sites. Children had a primary diagnosis of generalised anxiety disorder (GAD), social anxiety disorder (SoAD), specific phobia (SP) or separation anxiety disorder (SAD). Children and parents completed a semistructured clinical interview to assess the presence and severity of DSM-IV psychiatric disorders at preintervention, postintervention and follow-up. Linear mixture modelling was used to evaluate the primary research question and logistic modelling was used to investigate the secondary research question. RESULTS: In children with primary GAD, SAD or SoAD, there were no significant differences between delivery formats. However, children with primary SP showed significantly larger reductions in clinical severity following individual CBT compared to group CBT and guided parent-led CBT. The results were mirrored in the analysis of remission responses with the exception that individual CBT was no longer superior to group CBT for children with a primary SP. The difference between individual and group was not significant when follow-up data were examined separately. CONCLUSIONS: Data show there may be greater clinical benefit by allocating children with a primary SP to individual CBT, although future research on cost-effectiveness is needed to determine whether the additional clinical benefits justify the additional resources required. En ligne : http://dx.doi.org/10.1111/jcpp.12872 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368
in Journal of Child Psychology and Psychiatry > 59-7 (July 2018) . - p.763-772[article] The impact of treatment delivery format on response to cognitive behaviour therapy for preadolescent children with anxiety disorders [Texte imprimé et/ou numérique] / A. MCKINNON, Auteur ; R. KEERS, Auteur ; J. R. I. COLEMAN, Auteur ; K. J. LESTER, Auteur ; S. ROBERTS, Auteur ; Kristian ARENDT, Auteur ; Susan M. BOGELS, Auteur ; Peter COOPER, Auteur ; C. CRESWELL, Auteur ; Catharina A. HARTMAN, Auteur ; K. W. FJERMESTAD, Auteur ; T. IN-ALBON, Auteur ; K. LAVALLEE, Auteur ; H. J. LYNEHAM, Auteur ; P. SMITH, Auteur ; R. MEISER-STEDMAN, Auteur ; M. H. NAUTA, Auteur ; R. M. RAPEE, Auteur ; Y. REY, Auteur ; S. SCHNEIDER, Auteur ; W. K. SILVERMAN, Auteur ; M. THASTUM, Auteur ; K. THIRLWALL, Auteur ; Gro Janne WERGELAND, Auteur ; T. C. ELEY, Auteur ; J. L. HUDSON, Auteur . - 2018 . - p.763-772.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 59-7 (July 2018) . - p.763-772
Mots-clés : Anxiety cognitive therapy treatment trials Index. décimale : PER Périodiques Résumé : BACKGROUND: Several delivery formats of cognitive behaviour therapy (CBT) for child anxiety have been proposed, however, there is little consensus on the optimal delivery format. The primary goal of this study was to investigate the impact of the child's primary anxiety diagnosis on changes in clinical severity (of the primary problem) during individual CBT, group CBT and guided parent-led CBT. The secondary goal was to investigate the impact of the child's primary anxiety diagnosis on rates of remission for the three treatment formats. METHODS: A sample of 1,253 children (5-12 years; Mage = 9.3, SD = 1.7) was pooled from CBT trials carried out at 10 sites. Children had a primary diagnosis of generalised anxiety disorder (GAD), social anxiety disorder (SoAD), specific phobia (SP) or separation anxiety disorder (SAD). Children and parents completed a semistructured clinical interview to assess the presence and severity of DSM-IV psychiatric disorders at preintervention, postintervention and follow-up. Linear mixture modelling was used to evaluate the primary research question and logistic modelling was used to investigate the secondary research question. RESULTS: In children with primary GAD, SAD or SoAD, there were no significant differences between delivery formats. However, children with primary SP showed significantly larger reductions in clinical severity following individual CBT compared to group CBT and guided parent-led CBT. The results were mirrored in the analysis of remission responses with the exception that individual CBT was no longer superior to group CBT for children with a primary SP. The difference between individual and group was not significant when follow-up data were examined separately. CONCLUSIONS: Data show there may be greater clinical benefit by allocating children with a primary SP to individual CBT, although future research on cost-effectiveness is needed to determine whether the additional clinical benefits justify the additional resources required. En ligne : http://dx.doi.org/10.1111/jcpp.12872 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368 Cost-effectiveness of cognitive therapy as an early intervention for post-traumatic stress disorder in children and adolescents: a trial based evaluation and model / J. SHEARER in Journal of Child Psychology and Psychiatry, 59-7 (July 2018)
![]()
[article]
Titre : Cost-effectiveness of cognitive therapy as an early intervention for post-traumatic stress disorder in children and adolescents: a trial based evaluation and model Type de document : Texte imprimé et/ou numérique Auteurs : J. SHEARER, Auteur ; N. PAPANIKOLAOU, Auteur ; R. MEISER-STEDMAN, Auteur ; A. MCKINNON, Auteur ; Tim DALGLEISH, Auteur ; P. SMITH, Auteur ; C. DIXON, Auteur ; Sarah BYFORD, Auteur Article en page(s) : p.773-780 Langues : Anglais (eng) Mots-clés : Economic evaluation cognitive therapy post-traumatic stress disorder Index. décimale : PER Périodiques Résumé : BACKGROUND: Untreated post-traumatic stress disorder (PTSD) in children and adolescents is associated with a considerable economic burden on the health system, families and society. Recent research has demonstrated the potential efficacy of cognitive therapy as an early intervention for PTSD in children and adolescents. Children who experienced a single traumatic event in the previous two to six months and were randomized to cognitive therapy for PTSD (CT-PTSD) were significantly more likely to be PTSD-free compared to those randomized to usual care represented by waitlist control. The current study evaluated the economic impact of improvements in the treatment of PTSD in children and adolescents. METHODS: A cost-effectiveness analysis was conducted from the national health service/personal social services perspective with outcomes expressed as quality-adjusted life years (QALYs). Patient level costs and outcomes were collected during the 11 week clinical trial and extrapolated to a three year time horizon using economic modelling methods. Uncertainty was estimated using probabilistic sensitivity analysis and assumptions were tested using one way sensitivity analysis. RESULTS: The incremental cost-effectiveness ratio at 3 years was pound2,205 per QALY with a 60%-69% probability of CT-PTSD being cost-effective compared to usual care at the UK pound20,000 to pound30,000 per QALY decision threshold. CONCLUSIONS: This study provides preliminary evidence for the cost-effectiveness of cognitive therapy in this treatment population. Larger pragmatic trials with longer follow-up are indicated. En ligne : http://dx.doi.org/10.1111/jcpp.12851 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368
in Journal of Child Psychology and Psychiatry > 59-7 (July 2018) . - p.773-780[article] Cost-effectiveness of cognitive therapy as an early intervention for post-traumatic stress disorder in children and adolescents: a trial based evaluation and model [Texte imprimé et/ou numérique] / J. SHEARER, Auteur ; N. PAPANIKOLAOU, Auteur ; R. MEISER-STEDMAN, Auteur ; A. MCKINNON, Auteur ; Tim DALGLEISH, Auteur ; P. SMITH, Auteur ; C. DIXON, Auteur ; Sarah BYFORD, Auteur . - p.773-780.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 59-7 (July 2018) . - p.773-780
Mots-clés : Economic evaluation cognitive therapy post-traumatic stress disorder Index. décimale : PER Périodiques Résumé : BACKGROUND: Untreated post-traumatic stress disorder (PTSD) in children and adolescents is associated with a considerable economic burden on the health system, families and society. Recent research has demonstrated the potential efficacy of cognitive therapy as an early intervention for PTSD in children and adolescents. Children who experienced a single traumatic event in the previous two to six months and were randomized to cognitive therapy for PTSD (CT-PTSD) were significantly more likely to be PTSD-free compared to those randomized to usual care represented by waitlist control. The current study evaluated the economic impact of improvements in the treatment of PTSD in children and adolescents. METHODS: A cost-effectiveness analysis was conducted from the national health service/personal social services perspective with outcomes expressed as quality-adjusted life years (QALYs). Patient level costs and outcomes were collected during the 11 week clinical trial and extrapolated to a three year time horizon using economic modelling methods. Uncertainty was estimated using probabilistic sensitivity analysis and assumptions were tested using one way sensitivity analysis. RESULTS: The incremental cost-effectiveness ratio at 3 years was pound2,205 per QALY with a 60%-69% probability of CT-PTSD being cost-effective compared to usual care at the UK pound20,000 to pound30,000 per QALY decision threshold. CONCLUSIONS: This study provides preliminary evidence for the cost-effectiveness of cognitive therapy in this treatment population. Larger pragmatic trials with longer follow-up are indicated. En ligne : http://dx.doi.org/10.1111/jcpp.12851 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368 A longitudinal investigation of the role of parental responses in predicting children's post-traumatic distress / R. M. HILLER in Journal of Child Psychology and Psychiatry, 59-7 (July 2018)
![]()
[article]
Titre : A longitudinal investigation of the role of parental responses in predicting children's post-traumatic distress Type de document : Texte imprimé et/ou numérique Auteurs : R. M. HILLER, Auteur ; R. MEISER-STEDMAN, Auteur ; S. LOBO, Auteur ; C. CRESWELL, Auteur ; P. FEARON, Auteur ; A. EHLERS, Auteur ; L. MURRAY, Auteur ; Sarah L. HALLIGAN, Auteur Article en page(s) : p.781-789 Langues : Anglais (eng) Mots-clés : Longitudinal child cognitive behavioural parenting post-traumatic stress disorder Index. décimale : PER Périodiques Résumé : BACKGROUND: While parental post-trauma support is considered theoretically important for child adjustment, empirical evidence concerning the specific aspects of parental responding that influence child post-traumatic distress, or the processes via which any such impacts occur, is extremely limited. We conducted a longitudinal examination of whether parental post-trauma appraisals, trauma-specific support style and general parenting style predicted child post-traumatic stress symptom severity (PTSS) following trauma; and whether such influences operated via the child's own appraisals and coping style. METHOD: We recruited 132 parent-child pairs following children's experience of acute trauma. We examined whether parental responses assessed at 1-month post-trauma, predicted child PTSS at 6-month follow-up. Parental trauma-specific appraisals and responses, and general parenting style, were assessed via both self-report and direct observations. Child-report questionnaires were used to assess PTSS and potential mediators. RESULTS: Initial parent negative appraisals and encouragement of avoidant coping were associated with higher child-reported PTSS at 6-month follow-up. Predictive effects were maintained even when controlling for initial child symptom levels. Observational assessments broadly supported conclusions from self-report. There was evidence that parental influences may operate, in part, by influencing the child's own appraisals and coping responses. In contrast, there was no evidence for an influence of more "adaptive" support or general parenting style on child PTSS. CONCLUSIONS: Findings provide important insight into how elements of social support may influence child post-trauma outcomes. En ligne : http://dx.doi.org/10.1111/jcpp.12846 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368
in Journal of Child Psychology and Psychiatry > 59-7 (July 2018) . - p.781-789[article] A longitudinal investigation of the role of parental responses in predicting children's post-traumatic distress [Texte imprimé et/ou numérique] / R. M. HILLER, Auteur ; R. MEISER-STEDMAN, Auteur ; S. LOBO, Auteur ; C. CRESWELL, Auteur ; P. FEARON, Auteur ; A. EHLERS, Auteur ; L. MURRAY, Auteur ; Sarah L. HALLIGAN, Auteur . - p.781-789.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 59-7 (July 2018) . - p.781-789
Mots-clés : Longitudinal child cognitive behavioural parenting post-traumatic stress disorder Index. décimale : PER Périodiques Résumé : BACKGROUND: While parental post-trauma support is considered theoretically important for child adjustment, empirical evidence concerning the specific aspects of parental responding that influence child post-traumatic distress, or the processes via which any such impacts occur, is extremely limited. We conducted a longitudinal examination of whether parental post-trauma appraisals, trauma-specific support style and general parenting style predicted child post-traumatic stress symptom severity (PTSS) following trauma; and whether such influences operated via the child's own appraisals and coping style. METHOD: We recruited 132 parent-child pairs following children's experience of acute trauma. We examined whether parental responses assessed at 1-month post-trauma, predicted child PTSS at 6-month follow-up. Parental trauma-specific appraisals and responses, and general parenting style, were assessed via both self-report and direct observations. Child-report questionnaires were used to assess PTSS and potential mediators. RESULTS: Initial parent negative appraisals and encouragement of avoidant coping were associated with higher child-reported PTSS at 6-month follow-up. Predictive effects were maintained even when controlling for initial child symptom levels. Observational assessments broadly supported conclusions from self-report. There was evidence that parental influences may operate, in part, by influencing the child's own appraisals and coping responses. In contrast, there was no evidence for an influence of more "adaptive" support or general parenting style on child PTSS. CONCLUSIONS: Findings provide important insight into how elements of social support may influence child post-trauma outcomes. En ligne : http://dx.doi.org/10.1111/jcpp.12846 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368 Maternal sensitivity to distress, attachment and the development of callous-unemotional traits in young children / N. WRIGHT in Journal of Child Psychology and Psychiatry, 59-7 (July 2018)
![]()
[article]
Titre : Maternal sensitivity to distress, attachment and the development of callous-unemotional traits in young children Type de document : Texte imprimé et/ou numérique Auteurs : N. WRIGHT, Auteur ; J. HILL, Auteur ; H. SHARP, Auteur ; A. PICKLES, Auteur Article en page(s) : p.790-800 Langues : Anglais (eng) Mots-clés : attachment callous-unemotional (CU) traits infancy parenting Index. décimale : PER Périodiques Résumé : BACKGROUND: Callous-unemotional (CU) traits are characterized by a lack of responsiveness to the emotions of others, particularly negative emotions. A parenting environment where the child's own distress emotions are sensitively responded to may help foster the child's ability to respond to the emotions of others. We tested whether maternal sensitivity to distress, and other parenting characteristics, were associated with CU traits over the preschool period, and examined whether this was mediated via infant attachment status. METHOD: In an epidemiological cohort, CU traits were assessed at age 2.5, 3.5, and 5.0 years by mother report. Dimensions of parenting were assessed in free play at age 29 weeks in a stratified subsample of 272, and attachment status at 14 months (n = 265). Structural equation modelling with maximum likelihood estimation was used to examine predictions from parenting dimensions and attachment status. RESULTS: A parenting factor comprised of sensitivity to distress (n = 207), sensitivity to non-distress, positive regard toward the infant (or warmth), and intrusiveness, predicted child CU traits (p = .023). This effect was accounted for mainly by sensitivity to distress (p = .008) and positive regard (p = .023) which showed a synergistic effect as evidenced by a significant interaction (p = .01). This arose because the combination of low sensitivity to distress and low positive regard created the risk for elevated CU traits. Although sensitivity and positive regard predicted attachment security and disorganization, there were no associations between attachment status and CU traits. CONCLUSIONS: The finding of contributions from both sensitivity to distress and positive regard to reduced CU traits suggests that children's responsiveness to others' emotions may be increased by their own mothers' responsiveness to them and their mothers' warmth. There was no evidence that this was mediated via attachment status. Implications for intervention and future directions are discussed. En ligne : http://dx.doi.org/10.1111/jcpp.12867 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368
in Journal of Child Psychology and Psychiatry > 59-7 (July 2018) . - p.790-800[article] Maternal sensitivity to distress, attachment and the development of callous-unemotional traits in young children [Texte imprimé et/ou numérique] / N. WRIGHT, Auteur ; J. HILL, Auteur ; H. SHARP, Auteur ; A. PICKLES, Auteur . - p.790-800.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 59-7 (July 2018) . - p.790-800
Mots-clés : attachment callous-unemotional (CU) traits infancy parenting Index. décimale : PER Périodiques Résumé : BACKGROUND: Callous-unemotional (CU) traits are characterized by a lack of responsiveness to the emotions of others, particularly negative emotions. A parenting environment where the child's own distress emotions are sensitively responded to may help foster the child's ability to respond to the emotions of others. We tested whether maternal sensitivity to distress, and other parenting characteristics, were associated with CU traits over the preschool period, and examined whether this was mediated via infant attachment status. METHOD: In an epidemiological cohort, CU traits were assessed at age 2.5, 3.5, and 5.0 years by mother report. Dimensions of parenting were assessed in free play at age 29 weeks in a stratified subsample of 272, and attachment status at 14 months (n = 265). Structural equation modelling with maximum likelihood estimation was used to examine predictions from parenting dimensions and attachment status. RESULTS: A parenting factor comprised of sensitivity to distress (n = 207), sensitivity to non-distress, positive regard toward the infant (or warmth), and intrusiveness, predicted child CU traits (p = .023). This effect was accounted for mainly by sensitivity to distress (p = .008) and positive regard (p = .023) which showed a synergistic effect as evidenced by a significant interaction (p = .01). This arose because the combination of low sensitivity to distress and low positive regard created the risk for elevated CU traits. Although sensitivity and positive regard predicted attachment security and disorganization, there were no associations between attachment status and CU traits. CONCLUSIONS: The finding of contributions from both sensitivity to distress and positive regard to reduced CU traits suggests that children's responsiveness to others' emotions may be increased by their own mothers' responsiveness to them and their mothers' warmth. There was no evidence that this was mediated via attachment status. Implications for intervention and future directions are discussed. En ligne : http://dx.doi.org/10.1111/jcpp.12867 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368 Childhood developmental vulnerabilities associated with early life exposure to infectious and noninfectious diseases and maternal mental illness / M. J. GREEN in Journal of Child Psychology and Psychiatry, 59-7 (July 2018)
![]()
[article]
Titre : Childhood developmental vulnerabilities associated with early life exposure to infectious and noninfectious diseases and maternal mental illness Type de document : Texte imprimé et/ou numérique Auteurs : M. J. GREEN, Auteur ; M. KARIUKI, Auteur ; K. DEAN, Auteur ; K. R. LAURENS, Auteur ; S. TZOUMAKIS, Auteur ; F. HARRIS, Auteur ; Vaughan J. CARR, Auteur Article en page(s) : p.801-810 Langues : Anglais (eng) Mots-clés : Cns Risk factors developmental epidemiology developmental psychopathology infection maternal factors Index. décimale : PER Périodiques Résumé : BACKGROUND: Fetal exposure to infectious and noninfectious diseases may influence early childhood developmental functioning, on the path to later mental illness. Here, we investigated the effects of in utero exposure to maternal infection and noninfectious diseases during pregnancy on offspring developmental vulnerabilities at age 5 years, in the context of estimated effects for early childhood exposures to infectious and noninfectious diseases and maternal mental illness. METHODS: We used population data for 66,045 children from an intergenerational record linkage study (the New South Wales Child Development Study), for whom a cross-sectional assessment of five developmental competencies (physical, social, emotional, cognitive, and communication) was obtained at school entry, using the Australian Early Development Census (AEDC). Child and maternal exposures to infectious or noninfectious diseases were determined from the NSW Ministry of Health Admitted Patients Data Collection (APDC) and maternal mental illness exposure was derived from both APDC and Mental Health Ambulatory Data collections. Multinomial logistic regression analyses were used to examine unadjusted and adjusted associations between these physical and mental health exposures and child developmental vulnerabilities at age 5 years. RESULTS: Among the physical disease exposures, maternal infectious diseases during pregnancy and early childhood infection conferred the largest associations with developmental vulnerabilities at age 5 years; maternal noninfectious illness during pregnancy also retained small but significant associations with developmental vulnerabilities even when adjusted for other physical and mental illness exposures and covariates known to be associated with early childhood development (e.g., child's sex, socioeconomic disadvantage, young maternal age, prenatal smoking). Among all exposures examined, maternal mental illness first diagnosed prior to childbirth conferred the greatest odds of developmental vulnerability at age 5 years. CONCLUSIONS: Prenatal exposure to infectious or noninfectious diseases appear to influence early childhood physical, social, emotional and cognitive developmental vulnerabilities that may represent intermediate phenotypes for subsequent mental disorders. En ligne : http://dx.doi.org/10.1111/jcpp.12856 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368
in Journal of Child Psychology and Psychiatry > 59-7 (July 2018) . - p.801-810[article] Childhood developmental vulnerabilities associated with early life exposure to infectious and noninfectious diseases and maternal mental illness [Texte imprimé et/ou numérique] / M. J. GREEN, Auteur ; M. KARIUKI, Auteur ; K. DEAN, Auteur ; K. R. LAURENS, Auteur ; S. TZOUMAKIS, Auteur ; F. HARRIS, Auteur ; Vaughan J. CARR, Auteur . - p.801-810.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 59-7 (July 2018) . - p.801-810
Mots-clés : Cns Risk factors developmental epidemiology developmental psychopathology infection maternal factors Index. décimale : PER Périodiques Résumé : BACKGROUND: Fetal exposure to infectious and noninfectious diseases may influence early childhood developmental functioning, on the path to later mental illness. Here, we investigated the effects of in utero exposure to maternal infection and noninfectious diseases during pregnancy on offspring developmental vulnerabilities at age 5 years, in the context of estimated effects for early childhood exposures to infectious and noninfectious diseases and maternal mental illness. METHODS: We used population data for 66,045 children from an intergenerational record linkage study (the New South Wales Child Development Study), for whom a cross-sectional assessment of five developmental competencies (physical, social, emotional, cognitive, and communication) was obtained at school entry, using the Australian Early Development Census (AEDC). Child and maternal exposures to infectious or noninfectious diseases were determined from the NSW Ministry of Health Admitted Patients Data Collection (APDC) and maternal mental illness exposure was derived from both APDC and Mental Health Ambulatory Data collections. Multinomial logistic regression analyses were used to examine unadjusted and adjusted associations between these physical and mental health exposures and child developmental vulnerabilities at age 5 years. RESULTS: Among the physical disease exposures, maternal infectious diseases during pregnancy and early childhood infection conferred the largest associations with developmental vulnerabilities at age 5 years; maternal noninfectious illness during pregnancy also retained small but significant associations with developmental vulnerabilities even when adjusted for other physical and mental illness exposures and covariates known to be associated with early childhood development (e.g., child's sex, socioeconomic disadvantage, young maternal age, prenatal smoking). Among all exposures examined, maternal mental illness first diagnosed prior to childbirth conferred the greatest odds of developmental vulnerability at age 5 years. CONCLUSIONS: Prenatal exposure to infectious or noninfectious diseases appear to influence early childhood physical, social, emotional and cognitive developmental vulnerabilities that may represent intermediate phenotypes for subsequent mental disorders. En ligne : http://dx.doi.org/10.1111/jcpp.12856 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368 Foster care promotes adaptive functioning in early adolescence among children who experienced severe, early deprivation / Kathryn L. HUMPHREYS in Journal of Child Psychology and Psychiatry, 59-7 (July 2018)
![]()
[article]
Titre : Foster care promotes adaptive functioning in early adolescence among children who experienced severe, early deprivation Type de document : Texte imprimé et/ou numérique Auteurs : Kathryn L. HUMPHREYS, Auteur ; D. MIRON, Auteur ; K. A. MCLAUGHLIN, Auteur ; M. A. SHERIDAN, Auteur ; C. A. NELSON, Auteur ; N. A. FOX, Auteur ; C. H. ZEANAH, Auteur Article en page(s) : p.811-821 Langues : Anglais (eng) Mots-clés : Institutional care adaptive functioning foster care resilience Index. décimale : PER Périodiques Résumé : BACKGROUND: Experiences in early life lay the foundation for later development and functioning. Severe psychosocial deprivation, as experienced by children in early institutional care, constitutes an adverse experience with long-term negative consequences. The Bucharest Early Intervention Project sought to examine the effects of foster care as an alternative to institutional care for abandoned infants in Romanian institutions. METHODS: At a mean age of 22 months, institutionalized children were randomized to foster care or care as usual. At age 12 years, we followed-up with 98 of these children (50 randomized to foster care), as well as assessed 49 never institutionalized comparison children. Adaptive functioning was assessed across seven domains-mental health, physical health, substance use, risk-taking behavior, family relations, peer relations, and academic performance. Children at or above the threshold for adaptive functioning in at least six of seven domains were classified as having overall adaptive functioning in early adolescence. RESULTS: Among all children who had experienced severe early deprivation, 40% exhibited adaptive functioning. Children randomized to foster care were significantly more likely to exhibit adaptive functioning at age 12 years than children in the care as usual condition (56% vs. 23%). In support of external validity, children who met the threshold for adaptive functioning at age 12 years had higher IQs and were more physiologically responsive to stress. Among children randomized to foster care, children placed prior to age 20 months were more likely to meet the threshold for adaptive functioning than those placed after this age (79% vs. 46%). CONCLUSIONS: This study provides causal evidence that placing children into families following severe deprivation increases the likelihood of adaptive functioning in early adolescence. En ligne : http://dx.doi.org/10.1111/jcpp.12865 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368
in Journal of Child Psychology and Psychiatry > 59-7 (July 2018) . - p.811-821[article] Foster care promotes adaptive functioning in early adolescence among children who experienced severe, early deprivation [Texte imprimé et/ou numérique] / Kathryn L. HUMPHREYS, Auteur ; D. MIRON, Auteur ; K. A. MCLAUGHLIN, Auteur ; M. A. SHERIDAN, Auteur ; C. A. NELSON, Auteur ; N. A. FOX, Auteur ; C. H. ZEANAH, Auteur . - p.811-821.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 59-7 (July 2018) . - p.811-821
Mots-clés : Institutional care adaptive functioning foster care resilience Index. décimale : PER Périodiques Résumé : BACKGROUND: Experiences in early life lay the foundation for later development and functioning. Severe psychosocial deprivation, as experienced by children in early institutional care, constitutes an adverse experience with long-term negative consequences. The Bucharest Early Intervention Project sought to examine the effects of foster care as an alternative to institutional care for abandoned infants in Romanian institutions. METHODS: At a mean age of 22 months, institutionalized children were randomized to foster care or care as usual. At age 12 years, we followed-up with 98 of these children (50 randomized to foster care), as well as assessed 49 never institutionalized comparison children. Adaptive functioning was assessed across seven domains-mental health, physical health, substance use, risk-taking behavior, family relations, peer relations, and academic performance. Children at or above the threshold for adaptive functioning in at least six of seven domains were classified as having overall adaptive functioning in early adolescence. RESULTS: Among all children who had experienced severe early deprivation, 40% exhibited adaptive functioning. Children randomized to foster care were significantly more likely to exhibit adaptive functioning at age 12 years than children in the care as usual condition (56% vs. 23%). In support of external validity, children who met the threshold for adaptive functioning at age 12 years had higher IQs and were more physiologically responsive to stress. Among children randomized to foster care, children placed prior to age 20 months were more likely to meet the threshold for adaptive functioning than those placed after this age (79% vs. 46%). CONCLUSIONS: This study provides causal evidence that placing children into families following severe deprivation increases the likelihood of adaptive functioning in early adolescence. En ligne : http://dx.doi.org/10.1111/jcpp.12865 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368 Editorial Perspective: From schizophrenia polygenic risk score to vulnerability (endo-)phenotypes: translational pathways in child and adolescent mental health / M. POLETTI in Journal of Child Psychology and Psychiatry, 59-7 (July 2018)
![]()
[article]
Titre : Editorial Perspective: From schizophrenia polygenic risk score to vulnerability (endo-)phenotypes: translational pathways in child and adolescent mental health Type de document : Texte imprimé et/ou numérique Auteurs : M. POLETTI, Auteur ; A. RABALLO, Auteur Article en page(s) : p.822-825 Langues : Anglais (eng) Mots-clés : Schizophrenia development phenotype polygenic risk score psychopathology vulnerability Index. décimale : PER Périodiques Résumé : The Polygenic Risk Scores (PRS) approach is becoming increasingly prominent in psycho-behavioral research, however, its translational potential is still relatively underconceptualized. Indeed, PRS paradigm (which capitalizes on the combination of multiple genetic markers into a single proxy score to predict lifetime outcomes) has the potential to unravel some of the developmental complexities leading to severe mental disorders. With respect to schizophrenia, the application of PRS approach to child-adolescent cohorts from the general population, provides a crucial vantage point for understanding how presumed genetic predisposition is manifested during developmental years. Clearly, this is essential for etiological research as well as for the timely identification of the earliest stages of those specific psychopathological trajectories leading to psychosis. Therefore, the translational import of the PRS approach could improve our etiopathogenetic understanding of schizophrenia (e.g., allowing the disentanglement of the respective contribution of genetic and environmental risk factors along neurodevelopment) and further refine current staging models for early detection of vulnerability to psychosis (e.g., providing the rationale for more developmentally oriented reformulations of clinical high-risk criteria). En ligne : http://dx.doi.org/10.1111/jcpp.12857 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368
in Journal of Child Psychology and Psychiatry > 59-7 (July 2018) . - p.822-825[article] Editorial Perspective: From schizophrenia polygenic risk score to vulnerability (endo-)phenotypes: translational pathways in child and adolescent mental health [Texte imprimé et/ou numérique] / M. POLETTI, Auteur ; A. RABALLO, Auteur . - p.822-825.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 59-7 (July 2018) . - p.822-825
Mots-clés : Schizophrenia development phenotype polygenic risk score psychopathology vulnerability Index. décimale : PER Périodiques Résumé : The Polygenic Risk Scores (PRS) approach is becoming increasingly prominent in psycho-behavioral research, however, its translational potential is still relatively underconceptualized. Indeed, PRS paradigm (which capitalizes on the combination of multiple genetic markers into a single proxy score to predict lifetime outcomes) has the potential to unravel some of the developmental complexities leading to severe mental disorders. With respect to schizophrenia, the application of PRS approach to child-adolescent cohorts from the general population, provides a crucial vantage point for understanding how presumed genetic predisposition is manifested during developmental years. Clearly, this is essential for etiological research as well as for the timely identification of the earliest stages of those specific psychopathological trajectories leading to psychosis. Therefore, the translational import of the PRS approach could improve our etiopathogenetic understanding of schizophrenia (e.g., allowing the disentanglement of the respective contribution of genetic and environmental risk factors along neurodevelopment) and further refine current staging models for early detection of vulnerability to psychosis (e.g., providing the rationale for more developmentally oriented reformulations of clinical high-risk criteria). En ligne : http://dx.doi.org/10.1111/jcpp.12857 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368 Special Editorial: Open science and the Journal of Child Psychology & Psychiatry - next steps? / J. ASARNOW in Journal of Child Psychology and Psychiatry, 59-7 (July 2018)
![]()
[article]
Titre : Special Editorial: Open science and the Journal of Child Psychology & Psychiatry - next steps? Type de document : Texte imprimé et/ou numérique Auteurs : J. ASARNOW, Auteur ; Michael H. BLOCH, Auteur ; Daniel BRANDEIS, Auteur ; S. Alexandra BURT, Auteur ; P. FEARON, Auteur ; E. FOMBONNE, Auteur ; J. GREEN, Auteur ; A. GREGORY, Auteur ; M. GUNNAR, Auteur ; J. M. HALPERIN, Auteur ; C. HOLLIS, Auteur ; Sara JAFFEE, Auteur ; K. KLUMP, Auteur ; S. LANDAU, Auteur ; K. P. LESCH, Auteur ; A. J. T. OLDEHINKEL, Auteur ; B. PETERSON, Auteur ; P. RAMCHANDANI, Auteur ; Edmund J. S. SONUGA-BARKE, Auteur ; A. STRINGARIS, Auteur ; C. H. ZEANAH, Auteur Article en page(s) : p.826-827 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The JCPP works at the cutting edge of clinical science to publish ground-breaking research across the full range of topics in the field of child psychology and psychiatry. As JCPP editors, who are also active researchers in our own right, we are conscious of the threat posed to our field by what has come to be known as the reproducibility crisis - the fact that many published findings, initially trumpeted as important developments in the field, cannot be replicated and are therefore likely to be spurious (Nature Human Behaviour, 1, 2017, 21). The JCPP is conscious of its responsibility to play its part in addressing this issue as best it can. The roots of the problem are complex and its causes multifaceted. As one part of its response, the JCPP embraces the principles of open science and encourage preregistration of study protocols. Furthermore, we are working towards implementing new systems to promote preregistration with the hope of increasing scientific transparency and accountability and reducing the risks of selective reporting and posthoc rationalisation of findings (Journal of Child Psychology & Psychiatry, 59, 2018, 1). En ligne : http://dx.doi.org/10.1111/jcpp.12929 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368
in Journal of Child Psychology and Psychiatry > 59-7 (July 2018) . - p.826-827[article] Special Editorial: Open science and the Journal of Child Psychology & Psychiatry - next steps? [Texte imprimé et/ou numérique] / J. ASARNOW, Auteur ; Michael H. BLOCH, Auteur ; Daniel BRANDEIS, Auteur ; S. Alexandra BURT, Auteur ; P. FEARON, Auteur ; E. FOMBONNE, Auteur ; J. GREEN, Auteur ; A. GREGORY, Auteur ; M. GUNNAR, Auteur ; J. M. HALPERIN, Auteur ; C. HOLLIS, Auteur ; Sara JAFFEE, Auteur ; K. KLUMP, Auteur ; S. LANDAU, Auteur ; K. P. LESCH, Auteur ; A. J. T. OLDEHINKEL, Auteur ; B. PETERSON, Auteur ; P. RAMCHANDANI, Auteur ; Edmund J. S. SONUGA-BARKE, Auteur ; A. STRINGARIS, Auteur ; C. H. ZEANAH, Auteur . - p.826-827.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 59-7 (July 2018) . - p.826-827
Index. décimale : PER Périodiques Résumé : The JCPP works at the cutting edge of clinical science to publish ground-breaking research across the full range of topics in the field of child psychology and psychiatry. As JCPP editors, who are also active researchers in our own right, we are conscious of the threat posed to our field by what has come to be known as the reproducibility crisis - the fact that many published findings, initially trumpeted as important developments in the field, cannot be replicated and are therefore likely to be spurious (Nature Human Behaviour, 1, 2017, 21). The JCPP is conscious of its responsibility to play its part in addressing this issue as best it can. The roots of the problem are complex and its causes multifaceted. As one part of its response, the JCPP embraces the principles of open science and encourage preregistration of study protocols. Furthermore, we are working towards implementing new systems to promote preregistration with the hope of increasing scientific transparency and accountability and reducing the risks of selective reporting and posthoc rationalisation of findings (Journal of Child Psychology & Psychiatry, 59, 2018, 1). En ligne : http://dx.doi.org/10.1111/jcpp.12929 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368
[article]
Titre : Erratum Type de document : Texte imprimé et/ou numérique Article en page(s) : p.e1 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1111/jcpp.12935 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368
in Journal of Child Psychology and Psychiatry > 59-7 (July 2018) . - p.e1[article] Erratum [Texte imprimé et/ou numérique] . - p.e1.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 59-7 (July 2018) . - p.e1
Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1111/jcpp.12935 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368