Pubmed (TDAH) du 23/05/26
1. Childress A, Malik H, Potenziano J. The Impact of Untreated Attention-Deficit/Hyperactivity Disorder on Motor Vehicle Accidents: A Systematic Review and Meta-Analysis. Adv Ther;2026 (May 23)
INTRODUCTION: This meta-analysis quantified the dangers of driving with untreated ADHD and compares consequences for untreated drivers with ADHD to those of better publicized accident risk factors. METHODS: A systematic literature review and meta-analysis of published data was performed to determine the correlation between driving with untreated ADHD and motor vehicle accidents (MVAs). Separate analyses were performed for alcohol use and driving, excessive speed, cannabis use, sleepiness/fatigue, opioids/benzodiazepines, and cell phone use. RESULTS: Four studies showed significantly higher odds of an accident among untreated ADHD drivers versus the general population of drivers-a 93% increase [(significant pooled odds ratio (OR), 95% confidence interval (CI) for the overall effect, p < 0.001]. The odds of having an accident was increased by 85% in THC/cannabis users (significant pooled OR, 95% CI, p < 0.001); 162% increase in sleepy/tired drivers (significant pooled effect OR, 95% CI, p = 0.004); and 53% increase in opioid or benzodiazepine users (significant pooled OR, 95% CI, p < 0.001). CONCLUSION: This analysis found that MVAs occur significantly more frequently with drivers with untreated ADHD compared to the general population of drivers. Increasing awareness of accident risk among drivers with untreated ADHD and the positive impact of treating ADHD on driving highlights the importance of treating ADHD.
Lien vers le texte intégral (Open Access ou abonnement)
2. Gavcar EG, Avunduk S, Aksoy Avunduk S, Büber A. Investigation of phubbing behavior in attention deficit hyperactivity disorder and cognitive disengagement syndrome: a case-control study in adolescent. BMC Psychiatry;2026 (May 23)
BACKGROUND: Attention Deficit Hyperactivity Disorder (ADHD) is a common childhood neurodevelopmental disorder characterized by inattention, hyperactivity, and impulsivity beyond developmental expectations. Problematic technology engagement, including increased smartphone use, is frequently observed among adolescents with ADHD. Phubbing, a term combining ‘phone’ and ‘snubbing,’ refers to ignoring others in a social setting by focusing on one’s smartphone rather than engaging in face-to-face interaction and has been linked to impaired interpersonal communication. Cognitive Disengagement Syndrome (CDS), formerly referred to as sluggish cognitive tempo (SCT), is characterized by excessive daydreaming, mental confusion, low initiative, and slowed responding and is associated with social withdrawal. However, no prior studies have investigated ADHD-phubbing or CDS-phubbing relationships in adolescents. This study examined group differences in phubbing and explored associations among phubbing, ADHD symptoms, and CDS severity. METHODS: In this case-control study, 48 adolescents diagnosed with ADHD and 38 healthy controls aged 12-17 completed; Sociodemographic Data Form, General Phubbing Scale, and Conners-Wells Adolescent Self-Report Scale Short Form. Parents completed Child and Adolescent Behavior Inventory SCT Scale. ADHD was diagnosed via DSM-5 based clinical interviews. Group comparisons and correlation analyses were conducted using appropriate statistical tests. RESULTS: Phubbing scores were significantly higher in the ADHD group than in controls. Phubbing scores demonstrated significant positive correlations with self-reported ADHD symptom domains, including conduct problems, inattention, hyperactivity, and the ADHD Index. CDS severity did not reach significance within the ADHD group but was significantly associated with phubbing scores in the full sample. Adolescents whose CDS symptoms impaired social functioning reported higher phubbing scores. Daily smartphone use exceeding 3 hours and social media use were also associated with elevated phubbing scores. CONCLUSION: These findings indicate that phubbing scores is elevated among adolescents with ADHD and is positively associated with ADHD symptom severity. CDS-particularly when accompanied by social impairment-is also associated with higher phubbing scores. The results highlight the potential utility of assessing smartphone and other electronic technology use when evaluating adolescents with ADHD and CDS. However, given the cross-sectional nature of this study, causal or directional inferences cannot be drawn. Future research with larger and untreated samples is warranted. CLINICAL TRIAL NUMBER: Not applicable.
Lien vers le texte intégral (Open Access ou abonnement)
3. Tramoni M, Giudici L, Mancini S, Scheffler EL, Benites de Cerqueira B, Mossmann JB, Ferrari Barbosa DN, Trabattoni S, Mauri V, Nobile M, Crippa A, Marzocchi GM. « The incredible adventures of Apollo and Rosetta in space »: Training executive functions in children with attention-deficit/hyperactivity disorder. Appl Neuropsychol Child;2026 (May 23):1-12.
Children with Attention-Deficit/Hyperactivity Disorder (ADHD) frequently show deficits in Executive Functions (EFs), including inhibition, working memory, and cognitive flexibility. Digital games have recently been proposed as innovative tools to support EF development in this population. This randomized controlled trial investigated the effectiveness of The Incredible Adventures of Apollo and Rosetta in Space, a digital game designed to enhance executive functioning, in children aged 8-11 years with ADHD. Thirty-four participants were randomly assigned to an experimental group (n = 17), which played the game three times per week for three months, or to a control group (n = 17) that received no intervention. Neuropsychological tasks assessing inhibition, working memory, and cognitive flexibility, along with parent-reported questionnaires on ADHD symptoms and EF-related difficulties, were administered before and after the intervention. No significant group × time interactions emerged. However, exploratory effect size analyses revealed small-to-moderate directional improvements in the experimental group, particularly in cognitive flexibility, with modest gains in working memory and stable inhibition performance. Parent reports were consistent with these patterns, showing small improvements in attention in the experimental group and worsening EF-related behaviors in the control group. Although preliminary, these findings suggest that the game may be associated with meaningful patterns of change in abstract cognitive flexibility and working memory in children with ADHD, warranting further investigation into their generalization to daily functioning in larger samples. Trial registration: ClinicalTrials.gov ID NCT06881719.
Lien vers le texte intégral (Open Access ou abonnement)
4. Zhang Y, Li T, Jiang J, Li H, Sun R, Li Y, Chen W. Altered temporal organization of neural response dynamics during attention processing differentiates ADHD subtypes in children. Neuroimage Clin;2026 (May 23);50:104011.
BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) shows marked heterogeneity, and conventional event-related potential (ERP) measures have limited sensitivity to subtype differences. This study examined whether alterations in the temporal organization of neural responses during attentional processing differentiate ADHD subtypes. METHODS: Children with predominantly inattentive ADHD (ADHD-I), combined-type ADHD (ADHD-C), and typically developing (TD) controls completed an auditory oddball task during electroencephalography. Neural responses were analyzed using time-resolved scalp topographies, low-dimensional neural trajectory analysis, and data-driven neural state modeling. Associations with clinical symptoms were examined. RESULTS: Both ADHD subtypes showed altered temporal alignment of neural responses relative to TD children, particularly during target processing. Neural trajectories exhibited reduced differentiation between standard and target stimuli, with ADHD-I showing reduced trajectory separation and ADHD-C showing exaggerated but inefficient state excursions. Data-driven analyses further revealed subtype-specific alterations in neural state stability and transitions, which showed exploratory associations with attentional and behavioral impairment. CONCLUSIONS: ADHD is characterized by disrupted temporal organization of neural responses that is not captured by conventional ERP measures. Subtype-specific neural dynamics provide a mechanistic account of ADHD heterogeneity.
