Dépouillements

Editorial: Translational genetics of child psychopathology: a distant dream? / Barbara MAUGHAN in Journal of Child Psychology and Psychiatry, 55-10 (October 2014)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1065-1067 Titre : Editorial: Translational genetics of child psychopathology: a distant dream? Type de document : Texte imprimé et/ou numérique Auteurs : Barbara MAUGHAN, Auteur ; Edmund J. S. SONUGA-BARKE, Auteur Article en page(s) : p.1065-1067 Langues : Anglais (eng) Mots-clés : Translational genetics  child psychopathology  heritability  genetic variant markers  psychiatric genetics Index. décimale : PER Périodiques Résumé : For decades now twin, family and adoption studies have pointed to a substantial role for genetic factors in risk for psychiatric disorder. Behaviour genetic studies are not, of course, designed to tell us about the ‘genetic architecture’ of disorders – the number of risk variants involved, their frequency, or their effects sizes – but their findings clearly suggest that given the high levels of heritability detected, identifying the gene variants involved could provide important pointers to aetiology, and might well have implications for treatment. In and of themselves heritability findings have little practical value as a basis for a translational genetics of psychiatric disorders. They cannot help us identify pathophysiological pathways that need to be targeted through therapeutic innovation or inform the sort of tailoring of treatments to individual biological ‘types’ to promote personalized medicine. To do these things we need to move from estimating heritability to identifying specific genetic markers implicating specific neuro-biological systems. En ligne : http://dx.doi.org/10.1111/jcpp.12323 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=238 [article] Editorial: Translational genetics of child psychopathology: a distant dream? [Texte imprimé et/ou numérique] / Barbara MAUGHAN, Auteur ; Edmund J. S. SONUGA-BARKE, Auteur . - p.1065-1067. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1065-1067 Mots-clés : Translational genetics  child psychopathology  heritability  genetic variant markers  psychiatric genetics Index. décimale : PER Périodiques Résumé : For decades now twin, family and adoption studies have pointed to a substantial role for genetic factors in risk for psychiatric disorder. Behaviour genetic studies are not, of course, designed to tell us about the ‘genetic architecture’ of disorders – the number of risk variants involved, their frequency, or their effects sizes – but their findings clearly suggest that given the high levels of heritability detected, identifying the gene variants involved could provide important pointers to aetiology, and might well have implications for treatment. In and of themselves heritability findings have little practical value as a basis for a translational genetics of psychiatric disorders. They cannot help us identify pathophysiological pathways that need to be targeted through therapeutic innovation or inform the sort of tailoring of treatments to individual biological ‘types’ to promote personalized medicine. To do these things we need to move from estimating heritability to identifying specific genetic markers implicating specific neuro-biological systems. En ligne : http://dx.doi.org/10.1111/jcpp.12323 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=238

Research Review: Polygenic methods and their application to psychiatric traits / Naomi R. WRAY in Journal of Child Psychology and Psychiatry, 55-10 (October 2014)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1068-1087 Titre : Research Review: Polygenic methods and their application to psychiatric traits Type de document : Texte imprimé et/ou numérique Auteurs : Naomi R. WRAY, Auteur ; Sang Hong LEE, Auteur ; Divya MEHTA, Auteur ; Anna A. E. VINKHUYZEN, Auteur ; Frank DUDBRIDGE, Auteur ; Christel M. MIDDELDORP, Auteur Article en page(s) : p.1068-1087 Langues : Anglais (eng) Mots-clés : Polygenic risk scoring  genome-wide association studies  psychiatric disorders  heritability  SNP analyses  disease traits Index. décimale : PER Périodiques Résumé : Background Despite evidence from twin and family studies for an important contribution of genetic factors to both childhood and adult onset psychiatric disorders, identifying robustly associated specific DNA variants has proved challenging. In the pregenomics era the genetic architecture (number, frequency and effect size of risk variants) of complex genetic disorders was unknown. Empirical evidence for the genetic architecture of psychiatric disorders is emerging from the genetic studies of the last 5 years. Methods and scope We review the methods investigating the polygenic nature of complex disorders. We provide mini-guides to genomic profile (or polygenic) risk scoring and to estimation of variance (or heritability) from common SNPs; a glossary of key terms is also provided. We review results of applications of the methods to psychiatric disorders and related traits and consider how these methods inform on missing heritability, hidden heritability and still-missing heritability. Findings Genome-wide genotyping and sequencing studies are providing evidence that psychiatric disorders are truly polygenic, that is they have a genetic architecture of many genetic variants, including risk variants that are both common and rare in the population. Sample sizes published to date are mostly underpowered to detect effect sizes of the magnitude presented by nature, and these effect sizes may be constrained by the biological validity of the diagnostic constructs. Conclusions Increasing the sample size for genome wide association studies of psychiatric disorders will lead to the identification of more associated genetic variants, as already found for schizophrenia. These loci provide the starting point of functional analyses that might eventually lead to new prevention and treatment options and to improved biological validity of diagnostic constructs. Polygenic analyses will contribute further to our understanding of complex genetic traits as sample sizes increase and as sample resources become richer in phenotypic descriptors, both in terms of clinical symptoms and of nongenetic risk factors. En ligne : http://dx.doi.org/10.1111/jcpp.12295 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=238 [article] Research Review: Polygenic methods and their application to psychiatric traits [Texte imprimé et/ou numérique] / Naomi R. WRAY, Auteur ; Sang Hong LEE, Auteur ; Divya MEHTA, Auteur ; Anna A. E. VINKHUYZEN, Auteur ; Frank DUDBRIDGE, Auteur ; Christel M. MIDDELDORP, Auteur . - p.1068-1087. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1068-1087 Mots-clés : Polygenic risk scoring  genome-wide association studies  psychiatric disorders  heritability  SNP analyses  disease traits Index. décimale : PER Périodiques Résumé : Background Despite evidence from twin and family studies for an important contribution of genetic factors to both childhood and adult onset psychiatric disorders, identifying robustly associated specific DNA variants has proved challenging. In the pregenomics era the genetic architecture (number, frequency and effect size of risk variants) of complex genetic disorders was unknown. Empirical evidence for the genetic architecture of psychiatric disorders is emerging from the genetic studies of the last 5 years. Methods and scope We review the methods investigating the polygenic nature of complex disorders. We provide mini-guides to genomic profile (or polygenic) risk scoring and to estimation of variance (or heritability) from common SNPs; a glossary of key terms is also provided. We review results of applications of the methods to psychiatric disorders and related traits and consider how these methods inform on missing heritability, hidden heritability and still-missing heritability. Findings Genome-wide genotyping and sequencing studies are providing evidence that psychiatric disorders are truly polygenic, that is they have a genetic architecture of many genetic variants, including risk variants that are both common and rare in the population. Sample sizes published to date are mostly underpowered to detect effect sizes of the magnitude presented by nature, and these effect sizes may be constrained by the biological validity of the diagnostic constructs. Conclusions Increasing the sample size for genome wide association studies of psychiatric disorders will lead to the identification of more associated genetic variants, as already found for schizophrenia. These loci provide the starting point of functional analyses that might eventually lead to new prevention and treatment options and to improved biological validity of diagnostic constructs. Polygenic analyses will contribute further to our understanding of complex genetic traits as sample sizes increase and as sample resources become richer in phenotypic descriptors, both in terms of clinical symptoms and of nongenetic risk factors. En ligne : http://dx.doi.org/10.1111/jcpp.12295 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=238

Editorial Perspective: Why is there such a mismatch between traditional heritability estimates and molecular genetic findings for behavioural traits? / Anita THAPAR in Journal of Child Psychology and Psychiatry, 55-10 (October 2014)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1088-1091 Titre : Editorial Perspective: Why is there such a mismatch between traditional heritability estimates and molecular genetic findings for behavioural traits? Type de document : Texte imprimé et/ou numérique Auteurs : Anita THAPAR, Auteur ; Gordon HAROLD, Auteur Article en page(s) : p.1088-1091 Langues : Anglais (eng) Mots-clés : Molecular genetic studies  behaviour genetic studies  psychiatric disorders  behavioural traits  heritability  developmental psychopathology Index. décimale : PER Périodiques Résumé : The puzzle of the disparity between molecular- and traditional behaviour genetic study findings has prompted widespread discussion. Fundamental questions have been raised across the whole field of complex genetic traits as well as for behavioural traits. We consider explanations for recent findings and discuss what they mean for the field of developmental psychopathology. En ligne : http://dx.doi.org/10.1111/jcpp.12294 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=238 [article] Editorial Perspective: Why is there such a mismatch between traditional heritability estimates and molecular genetic findings for behavioural traits? [Texte imprimé et/ou numérique] / Anita THAPAR, Auteur ; Gordon HAROLD, Auteur . - p.1088-1091. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1088-1091 Mots-clés : Molecular genetic studies  behaviour genetic studies  psychiatric disorders  behavioural traits  heritability  developmental psychopathology Index. décimale : PER Périodiques Résumé : The puzzle of the disparity between molecular- and traditional behaviour genetic study findings has prompted widespread discussion. Fundamental questions have been raised across the whole field of complex genetic traits as well as for behavioural traits. We consider explanations for recent findings and discuss what they mean for the field of developmental psychopathology. En ligne : http://dx.doi.org/10.1111/jcpp.12294 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=238

Practitioner Review: A critical perspective on gene–environment interaction models – what impact should they have on clinical perceptions and practice? / Marcus R. MUNAFO in Journal of Child Psychology and Psychiatry, 55-10 (October 2014)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1092-1101 Titre : Practitioner Review: A critical perspective on gene–environment interaction models – what impact should they have on clinical perceptions and practice? Type de document : Texte imprimé et/ou numérique Auteurs : Marcus R. MUNAFO, Auteur ; Stanley ZAMMIT, Auteur ; Jonathan FLINT, Auteur Article en page(s) : p.1092-1101 Langues : Anglais (eng) Mots-clés : Genetics  genome-wide association studies  heritability  gene × environment interaction  psychiatric disorder Index. décimale : PER Périodiques Résumé : Background Psychiatric disorders run in families, and early twin, family and adoption studies confirmed that this was due in part to shared genetic inheritance. While candidate gene studies largely failed to reliably identify genetic variants associated with psychiatric disorders, genome-wide association studies are beginning to do so. However, the proportion of phenotypic variance explained remains well below what would be expected from previous heritability estimates. Scope We review possible reasons for this ‘missing heritability’, and whether incorporating gene by environment interactions into our models will substantially improve our understanding of the aetiology of psychiatric disorders, and inform clinical perceptions and practice. Findings We discuss potential limitations of the gene by environment interaction approach. In particular, we discuss whether these are likely to be a major contributor to psychiatric disorders at the level of the specific interaction (as opposed to at an aggregate level). Conclusions Gene by environment interaction studies offered initial promise that a far greater proportion of phenotypic variance could be explained by incorporating measures of environmental exposures into genetic studies. However, in our opinion, there are few (if any) clear examples of gene by environment interactions in psychiatry, and their scope for informing either our understanding of disease pathology or clinical practice remains limited at present. En ligne : http://dx.doi.org/10.1111/jcpp.12261 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=238 [article] Practitioner Review: A critical perspective on gene–environment interaction models – what impact should they have on clinical perceptions and practice? [Texte imprimé et/ou numérique] / Marcus R. MUNAFO, Auteur ; Stanley ZAMMIT, Auteur ; Jonathan FLINT, Auteur . - p.1092-1101. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1092-1101 Mots-clés : Genetics  genome-wide association studies  heritability  gene × environment interaction  psychiatric disorder Index. décimale : PER Périodiques Résumé : Background Psychiatric disorders run in families, and early twin, family and adoption studies confirmed that this was due in part to shared genetic inheritance. While candidate gene studies largely failed to reliably identify genetic variants associated with psychiatric disorders, genome-wide association studies are beginning to do so. However, the proportion of phenotypic variance explained remains well below what would be expected from previous heritability estimates. Scope We review possible reasons for this ‘missing heritability’, and whether incorporating gene by environment interactions into our models will substantially improve our understanding of the aetiology of psychiatric disorders, and inform clinical perceptions and practice. Findings We discuss potential limitations of the gene by environment interaction approach. In particular, we discuss whether these are likely to be a major contributor to psychiatric disorders at the level of the specific interaction (as opposed to at an aggregate level). Conclusions Gene by environment interaction studies offered initial promise that a far greater proportion of phenotypic variance could be explained by incorporating measures of environmental exposures into genetic studies. However, in our opinion, there are few (if any) clear examples of gene by environment interactions in psychiatry, and their scope for informing either our understanding of disease pathology or clinical practice remains limited at present. En ligne : http://dx.doi.org/10.1111/jcpp.12261 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=238

Commentary: G × E in child psychiatry and psychology: a broadening of the scope of enquiry as prompted by Munafò et al. (2014) / Michael RUTTER in Journal of Child Psychology and Psychiatry, 55-10 (October 2014)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1102-1104 Titre : Commentary: G × E in child psychiatry and psychology: a broadening of the scope of enquiry as prompted by Munafò et al. (2014) Type de document : Texte imprimé et/ou numérique Auteurs : Michael RUTTER, Auteur Article en page(s) : p.1102-1104 Langues : Anglais (eng) Mots-clés : Gene–environment interactions  G × E correlations  biological pathways  child mental health disorders Index. décimale : PER Périodiques Résumé : The accompanying Practitioner Review by Munafò et al. (2014) presents two main arguments: (1) that there are few (if any) examples of G × E in psychiatry so it cannot aid gene discovery, and (2) that genome-wide association studies (GWAS) are already yielding important findings. With respect to the supposed weakness of G × E research, they fail to mention any of the substantial body of evidence in support of G × E – see various chapters in Dodge and Rutter (2011). En ligne : http://dx.doi.org/10.1111/jcpp.12309 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=238 [article] Commentary: G × E in child psychiatry and psychology: a broadening of the scope of enquiry as prompted by Munafò et al. (2014) [Texte imprimé et/ou numérique] / Michael RUTTER, Auteur . - p.1102-1104. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1102-1104 Mots-clés : Gene–environment interactions  G × E correlations  biological pathways  child mental health disorders Index. décimale : PER Périodiques Résumé : The accompanying Practitioner Review by Munafò et al. (2014) presents two main arguments: (1) that there are few (if any) examples of G × E in psychiatry so it cannot aid gene discovery, and (2) that genome-wide association studies (GWAS) are already yielding important findings. With respect to the supposed weakness of G × E research, they fail to mention any of the substantial body of evidence in support of G × E – see various chapters in Dodge and Rutter (2011). En ligne : http://dx.doi.org/10.1111/jcpp.12309 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=238

Commentary: Response to commentary by Rutter on Munafo et al. (2014) / Marcus R. MUNAFO in Journal of Child Psychology and Psychiatry, 55-10 (October 2014)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1105-1106 Titre : Commentary: Response to commentary by Rutter on Munafo et al. (2014) Type de document : Texte imprimé et/ou numérique Auteurs : Marcus R. MUNAFO, Auteur ; Stanley ZAMMIT, Auteur ; Jonathan FLINT, Auteur Article en page(s) : p.1105-1106 Langues : Anglais (eng) Mots-clés : Gene–environment (G×E) interactions, locus-specific  genome wide  psychiatric phenotypes Index. décimale : PER Périodiques Résumé : Rutter's commentary (Rutter, 2014) on our article (Munafò et al., 2014) provides us the opportunity to clarify some issues that he (and therefore, we suspect, others) may have misunderstood. En ligne : http://dx.doi.org/10.1111/jcpp.12308 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=239 [article] Commentary: Response to commentary by Rutter on Munafo et al. (2014) [Texte imprimé et/ou numérique] / Marcus R. MUNAFO, Auteur ; Stanley ZAMMIT, Auteur ; Jonathan FLINT, Auteur . - p.1105-1106. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1105-1106 Mots-clés : Gene–environment (G×E) interactions, locus-specific  genome wide  psychiatric phenotypes Index. décimale : PER Périodiques Résumé : Rutter's commentary (Rutter, 2014) on our article (Munafò et al., 2014) provides us the opportunity to clarify some issues that he (and therefore, we suspect, others) may have misunderstood. En ligne : http://dx.doi.org/10.1111/jcpp.12308 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=239

Depressive comorbidity in preschool anxiety disorder / Kai VON KLITZING in Journal of Child Psychology and Psychiatry, 55-10 (October 2014)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1107-1116 Titre : Depressive comorbidity in preschool anxiety disorder Type de document : Texte imprimé et/ou numérique Auteurs : Kai VON KLITZING, Auteur ; Lars O. WHITE, Auteur ; Yvonne OTTO, Auteur ; Sandra FUCHS, Auteur ; Helen L. EGGER, Auteur ; Annette M. KLEIN, Auteur Article en page(s) : p.1107-1116 Langues : Anglais (eng) Mots-clés : Anxiety  depression  comorbidity  preschool children Index. décimale : PER Périodiques Résumé : Background The threshold for clinical relevance of preschool anxiety has recently come under increasing scrutiny in view of large variations in prevalence estimates. We studied the impact of presence/absence of additional depressive comorbidity (symptoms and/or diagnosis) on preschoolers with anxiety disorders in relation to clinical phenomenology, family, and peer problems compared to healthy controls. Method A population of 1738 preschoolers were screened and oversampled for internalizing symptoms from community sites, yielding a sample of 236 children. Results Using a multi-informant approach (mother, father, teacher, child), we found evidence that children with anxiety disorders and depressive comorbidity display a greater internalizing symptom-load, more peer problems and live in families with more psychosocial impairment (poor family functioning, family adversity, maternal mental health problems). The pure anxiety group was merely dissociable from controls with regard to internalizing symptoms and family adversity. Conclusion The presence of depressive comorbidity in anxiety disorders may mark the transition to a more detrimental and impairing disorder at preschool age. En ligne : http://dx.doi.org/10.1111/jcpp.12222 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=239 [article] Depressive comorbidity in preschool anxiety disorder [Texte imprimé et/ou numérique] / Kai VON KLITZING, Auteur ; Lars O. WHITE, Auteur ; Yvonne OTTO, Auteur ; Sandra FUCHS, Auteur ; Helen L. EGGER, Auteur ; Annette M. KLEIN, Auteur . - p.1107-1116. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1107-1116 Mots-clés : Anxiety  depression  comorbidity  preschool children Index. décimale : PER Périodiques Résumé : Background The threshold for clinical relevance of preschool anxiety has recently come under increasing scrutiny in view of large variations in prevalence estimates. We studied the impact of presence/absence of additional depressive comorbidity (symptoms and/or diagnosis) on preschoolers with anxiety disorders in relation to clinical phenomenology, family, and peer problems compared to healthy controls. Method A population of 1738 preschoolers were screened and oversampled for internalizing symptoms from community sites, yielding a sample of 236 children. Results Using a multi-informant approach (mother, father, teacher, child), we found evidence that children with anxiety disorders and depressive comorbidity display a greater internalizing symptom-load, more peer problems and live in families with more psychosocial impairment (poor family functioning, family adversity, maternal mental health problems). The pure anxiety group was merely dissociable from controls with regard to internalizing symptoms and family adversity. Conclusion The presence of depressive comorbidity in anxiety disorders may mark the transition to a more detrimental and impairing disorder at preschool age. En ligne : http://dx.doi.org/10.1111/jcpp.12222 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=239

Inhibitory control and delay aversion in unaffected preschoolers with a positive family history of attention deficit hyperactivity disorder / Ursula PAULI-POTT in Journal of Child Psychology and Psychiatry, 55-10 (October 2014)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1117-1124 Titre : Inhibitory control and delay aversion in unaffected preschoolers with a positive family history of attention deficit hyperactivity disorder Type de document : Texte imprimé et/ou numérique Auteurs : Ursula PAULI-POTT, Auteur ; Alisa ROLLER, Auteur ; Monika HEINZEL-GUTENBRUNNER, Auteur ; Tanja MINGEBACH, Auteur ; Silke DALIR, Auteur ; Katja BECKER, Auteur Article en page(s) : p.1117-1124 Langues : Anglais (eng) Mots-clés : Attention deficit hyperactivity disorder  hot and cool executive functions  cognitive control  response inhibition Index. décimale : PER Périodiques Résumé : Background From current theories on the etiology of attention deficit hyperactivity disorder (ADHD), it can be inferred that delay aversion (DA) and deficits in inhibitory control (IC) constitute basic deficits or endophenotypes of the disorder that already occur in the preschool period. This implies an occurrence of the characteristics in unaffected preschoolers with a positive family history of ADHD. Thus, it is hypothesized that preschoolers who are not affected by ADHD but who have first-degree relatives who suffer, or have suffered, from ADHD show deficits in IC and heightened DA in comparison to preschoolers from the general population. Methods Thirty unaffected preschoolers with a positive family history of ADHD were compared with 30 control children matched with respect to age in months, gender, intelligence, and maternal education level. The groups also did not differ in terms of maternal depressive symptoms and the number of psychosocial family risks. A set of age-appropriate neuropsychological tasks on executive IC (e.g. Puppet Says, Day-Night, relying on Go-NoGo and interference paradigms) and DA (e.g. Snack Delay, Gift Wrap, relying on delay of gratification paradigm) was conducted. Results Unaffected preschoolers showed significantly higher DA than control children (t(29) = ?2.57, p .008). The result did not change when subclinical ADHD symptoms and symptoms of oppositional defiant disorder were controlled for (F(1,29) = 5.21, p .031). Differences in IC did not reach statistical significance. Conclusion The results are compatible with the assumption that DA constitutes a familial vulnerability marker that can be validly assessed in the preschool period. As this is the first study to address this issue in preschoolers, more research is needed to confirm and further analyze the significance of DA assessments specifically at this developmental stage. En ligne : http://dx.doi.org/10.1111/jcpp.12230 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=239 [article] Inhibitory control and delay aversion in unaffected preschoolers with a positive family history of attention deficit hyperactivity disorder [Texte imprimé et/ou numérique] / Ursula PAULI-POTT, Auteur ; Alisa ROLLER, Auteur ; Monika HEINZEL-GUTENBRUNNER, Auteur ; Tanja MINGEBACH, Auteur ; Silke DALIR, Auteur ; Katja BECKER, Auteur . - p.1117-1124. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1117-1124 Mots-clés : Attention deficit hyperactivity disorder  hot and cool executive functions  cognitive control  response inhibition Index. décimale : PER Périodiques Résumé : Background From current theories on the etiology of attention deficit hyperactivity disorder (ADHD), it can be inferred that delay aversion (DA) and deficits in inhibitory control (IC) constitute basic deficits or endophenotypes of the disorder that already occur in the preschool period. This implies an occurrence of the characteristics in unaffected preschoolers with a positive family history of ADHD. Thus, it is hypothesized that preschoolers who are not affected by ADHD but who have first-degree relatives who suffer, or have suffered, from ADHD show deficits in IC and heightened DA in comparison to preschoolers from the general population. Methods Thirty unaffected preschoolers with a positive family history of ADHD were compared with 30 control children matched with respect to age in months, gender, intelligence, and maternal education level. The groups also did not differ in terms of maternal depressive symptoms and the number of psychosocial family risks. A set of age-appropriate neuropsychological tasks on executive IC (e.g. Puppet Says, Day-Night, relying on Go-NoGo and interference paradigms) and DA (e.g. Snack Delay, Gift Wrap, relying on delay of gratification paradigm) was conducted. Results Unaffected preschoolers showed significantly higher DA than control children (t(29) = ?2.57, p .008). The result did not change when subclinical ADHD symptoms and symptoms of oppositional defiant disorder were controlled for (F(1,29) = 5.21, p .031). Differences in IC did not reach statistical significance. Conclusion The results are compatible with the assumption that DA constitutes a familial vulnerability marker that can be validly assessed in the preschool period. As this is the first study to address this issue in preschoolers, more research is needed to confirm and further analyze the significance of DA assessments specifically at this developmental stage. En ligne : http://dx.doi.org/10.1111/jcpp.12230 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=239

Increase in child behavior problems among urban Brazilian 4-year olds: 1993 and 2004 Pelotas birth cohorts / Alicia MATIJASEVICH in Journal of Child Psychology and Psychiatry, 55-10 (October 2014)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1125-1134 Titre : Increase in child behavior problems among urban Brazilian 4-year olds: 1993 and 2004 Pelotas birth cohorts Type de document : Texte imprimé et/ou numérique Auteurs : Alicia MATIJASEVICH, Auteur ; Elizabeth MURRAY, Auteur ; Alan STEIN, Auteur ; Luciana ANSELMI, Auteur ; Ana M. MENEZES, Auteur ; Iná S. SANTOS, Auteur ; Aluísio J. D. BARROS, Auteur ; Denise P. GIGANTE, Auteur ; Fernando C. BARROS, Auteur ; Cesar G. VICTORA, Auteur Article en page(s) : p.1125-1134 Langues : Anglais (eng) Mots-clés : Mental health  behavior problems  child behavior check list  longitudinal studies Index. décimale : PER Périodiques Résumé : Background There are an increasing number of reports on time trends in child and adolescent psychological problems but none from low- and middle-income countries, and very few covering the preschool period. The aim was to investigate changes in preschool behavioral/emotional problems in two birth cohorts from a middle-income country born 11 years apart. Methods We analyzed data from the 1993 and 2004 Pelotas birth cohort studies from Brazil. A subsample of 4-year olds from the 1993 cohort (634) and all 4-year olds from the 2004 cohort (3750) were assessed for behavioral/emotional problems through maternal report using the Child Behavior Checklist (CBCL). Response rates in these two population-based cohorts were above 90%. Results We found a significant increase in CBCL total problems, internalizing and externalizing mean scores over the 11-year period. For 1993 and 2004 Pelotas cohorts, respectively, CBCL mean values (SE) total problems scores were 27.9 (0.8) and 34.7 (0.3); for internalizing scores, 5.7 (0.2) and 6.3 (0.1) and for externalizing scores, 12.4 (0.4) and 15.5 (0.1). After adjusting for confounding variables, the largest increase from 1993 to 2004 was identified in the aggressive behavior syndrome score (Cohen's d = .50), followed by the externalizing problem score (Cohen's d = .40) and CBCL total problem score (Cohen's d = .36), respectively. The rise in child psychological problems was more marked in children from families with fewer assets and with less educated mothers. Conclusions Our findings provide evidence for a substantial increase in preschool behavioral problems among children in Brazil over an 11-year period. En ligne : http://dx.doi.org/10.1111/jcpp.12236 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=239 [article] Increase in child behavior problems among urban Brazilian 4-year olds: 1993 and 2004 Pelotas birth cohorts [Texte imprimé et/ou numérique] / Alicia MATIJASEVICH, Auteur ; Elizabeth MURRAY, Auteur ; Alan STEIN, Auteur ; Luciana ANSELMI, Auteur ; Ana M. MENEZES, Auteur ; Iná S. SANTOS, Auteur ; Aluísio J. D. BARROS, Auteur ; Denise P. GIGANTE, Auteur ; Fernando C. BARROS, Auteur ; Cesar G. VICTORA, Auteur . - p.1125-1134. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1125-1134 Mots-clés : Mental health  behavior problems  child behavior check list  longitudinal studies Index. décimale : PER Périodiques Résumé : Background There are an increasing number of reports on time trends in child and adolescent psychological problems but none from low- and middle-income countries, and very few covering the preschool period. The aim was to investigate changes in preschool behavioral/emotional problems in two birth cohorts from a middle-income country born 11 years apart. Methods We analyzed data from the 1993 and 2004 Pelotas birth cohort studies from Brazil. A subsample of 4-year olds from the 1993 cohort (634) and all 4-year olds from the 2004 cohort (3750) were assessed for behavioral/emotional problems through maternal report using the Child Behavior Checklist (CBCL). Response rates in these two population-based cohorts were above 90%. Results We found a significant increase in CBCL total problems, internalizing and externalizing mean scores over the 11-year period. For 1993 and 2004 Pelotas cohorts, respectively, CBCL mean values (SE) total problems scores were 27.9 (0.8) and 34.7 (0.3); for internalizing scores, 5.7 (0.2) and 6.3 (0.1) and for externalizing scores, 12.4 (0.4) and 15.5 (0.1). After adjusting for confounding variables, the largest increase from 1993 to 2004 was identified in the aggressive behavior syndrome score (Cohen's d = .50), followed by the externalizing problem score (Cohen's d = .40) and CBCL total problem score (Cohen's d = .36), respectively. The rise in child psychological problems was more marked in children from families with fewer assets and with less educated mothers. Conclusions Our findings provide evidence for a substantial increase in preschool behavioral problems among children in Brazil over an 11-year period. En ligne : http://dx.doi.org/10.1111/jcpp.12236 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=239

Developmental association of prosocial behaviour with aggression, anxiety and depression from infancy to preadolescence / Amélie NANTEL-VIVIER in Journal of Child Psychology and Psychiatry, 55-10 (October 2014)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1135-1144 Titre : Developmental association of prosocial behaviour with aggression, anxiety and depression from infancy to preadolescence Type de document : Texte imprimé et/ou numérique Auteurs : Amélie NANTEL-VIVIER, Auteur ; Robert O. PIHL, Auteur ; Sylvana M. CÔTÉ, Auteur ; Richard E. TREMBLAY, Auteur Article en page(s) : p.1135-1144 Langues : Anglais (eng) Mots-clés : Prosociality  aggression  anxiety  depression  development Index. décimale : PER Périodiques Résumé : Background Research on associations between children's prosocial behaviour and mental health has provided mixed evidence. The present study sought to describe and predict the joint development of prosocial behaviour with externalizing and internalizing problems (physical aggression, anxiety and depression) from 2 to 11 years of age. Method Data were drawn from the National Longitudinal Survey of Children and Youth (NLSCY). Biennial prosocial behaviour, physical aggression, anxiety and depression maternal ratings were sought for 10,700 children aged 0 to 9 years at the first assessment point. Results While a negative association was observed between prosociality and physical aggression, more complex associations emerged with internalizing problems. Being a boy decreased the likelihood of membership in the high prosocial trajectory. Maternal depression increased the likelihood of moderate aggression, but also of joint high prosociality/low aggression. Low family income predicted the joint development of high prosociality with high physical aggression and high depression. Conclusions Individual differences exist in the association of prosocial behaviour with mental health. While high prosociality tends to co-occur with low levels of mental health problems, high prosociality and internalizing/externalizing problems can co-occur in subgroups of children. Child, mother and family characteristics are predictive of individual differences in prosocial behaviour and mental health development. Mechanisms underlying these associations warrant future investigations. En ligne : http://dx.doi.org/10.1111/jcpp.12235 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=239 [article] Developmental association of prosocial behaviour with aggression, anxiety and depression from infancy to preadolescence [Texte imprimé et/ou numérique] / Amélie NANTEL-VIVIER, Auteur ; Robert O. PIHL, Auteur ; Sylvana M. CÔTÉ, Auteur ; Richard E. TREMBLAY, Auteur . - p.1135-1144. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1135-1144 Mots-clés : Prosociality  aggression  anxiety  depression  development Index. décimale : PER Périodiques Résumé : Background Research on associations between children's prosocial behaviour and mental health has provided mixed evidence. The present study sought to describe and predict the joint development of prosocial behaviour with externalizing and internalizing problems (physical aggression, anxiety and depression) from 2 to 11 years of age. Method Data were drawn from the National Longitudinal Survey of Children and Youth (NLSCY). Biennial prosocial behaviour, physical aggression, anxiety and depression maternal ratings were sought for 10,700 children aged 0 to 9 years at the first assessment point. Results While a negative association was observed between prosociality and physical aggression, more complex associations emerged with internalizing problems. Being a boy decreased the likelihood of membership in the high prosocial trajectory. Maternal depression increased the likelihood of moderate aggression, but also of joint high prosociality/low aggression. Low family income predicted the joint development of high prosociality with high physical aggression and high depression. Conclusions Individual differences exist in the association of prosocial behaviour with mental health. While high prosociality tends to co-occur with low levels of mental health problems, high prosociality and internalizing/externalizing problems can co-occur in subgroups of children. Child, mother and family characteristics are predictive of individual differences in prosocial behaviour and mental health development. Mechanisms underlying these associations warrant future investigations. En ligne : http://dx.doi.org/10.1111/jcpp.12235 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=239

Risk-taking and sensation-seeking propensity in postinstitutionalized early adolescents / Michelle M. LOMAN in Journal of Child Psychology and Psychiatry, 55-10 (October 2014)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1145-1152 Titre : Risk-taking and sensation-seeking propensity in postinstitutionalized early adolescents Type de document : Texte imprimé et/ou numérique Auteurs : Michelle M. LOMAN, Auteur ; Anna E. JOHNSON, Auteur ; Karina QUEVEDO, Auteur ; Theresa L. LAFAVOR, Auteur ; Megan R. GUNNAR, Auteur Article en page(s) : p.1145-1152 Langues : Anglais (eng) Mots-clés : Risk-taking  Sensation-seeking  international adoption  institutional care  adolescence Index. décimale : PER Périodiques Résumé : Background Youth with histories of institutional/orphanage care are at increased risk for externalizing and internalizing problems during childhood and adolescence. Although these problems have been well described, the related adolescent behaviors of risk-taking and sensation-seeking have not yet been explored in this population. This study examined risk-taking and sensation-seeking propensity, and associations with conduct problems and depressive symptoms, in early adolescents who were adopted as young children from institutional care. Methods Risk-taking and sensation-seeking propensities of 12- and 13-year-old postinstitutionalized (PI; n = 54) adolescents were compared with two groups: youth who were internationally adopted early from foster care (PFC; n = 44) and nonadopted youth (NA; n = 58). Participants were recruited to equally represent pre/early- and mid/late-pubertal stages within each group. Participants completed the youth version of the Balloon Analogue Risk Task (Lejuez et al., ) and the Sensation-Seeking Scale for Children (Russo et al., ). Parents completed clinical ratings of participants' conduct problems and depressive symptoms. Results En ligne : http://dx.doi.org/10.1111/jcpp.12208 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=239 [article] Risk-taking and sensation-seeking propensity in postinstitutionalized early adolescents [Texte imprimé et/ou numérique] / Michelle M. LOMAN, Auteur ; Anna E. JOHNSON, Auteur ; Karina QUEVEDO, Auteur ; Theresa L. LAFAVOR, Auteur ; Megan R. GUNNAR, Auteur . - p.1145-1152. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1145-1152 Mots-clés : Risk-taking  Sensation-seeking  international adoption  institutional care  adolescence Index. décimale : PER Périodiques Résumé : Background Youth with histories of institutional/orphanage care are at increased risk for externalizing and internalizing problems during childhood and adolescence. Although these problems have been well described, the related adolescent behaviors of risk-taking and sensation-seeking have not yet been explored in this population. This study examined risk-taking and sensation-seeking propensity, and associations with conduct problems and depressive symptoms, in early adolescents who were adopted as young children from institutional care. Methods Risk-taking and sensation-seeking propensities of 12- and 13-year-old postinstitutionalized (PI; n = 54) adolescents were compared with two groups: youth who were internationally adopted early from foster care (PFC; n = 44) and nonadopted youth (NA; n = 58). Participants were recruited to equally represent pre/early- and mid/late-pubertal stages within each group. Participants completed the youth version of the Balloon Analogue Risk Task (Lejuez et al., ) and the Sensation-Seeking Scale for Children (Russo et al., ). Parents completed clinical ratings of participants' conduct problems and depressive symptoms. Results En ligne : http://dx.doi.org/10.1111/jcpp.12208 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=239

Adolescent deviant peer clustering as an amplifying mechanism underlying the progression from early substance use to late adolescent dependence / Mark J. VAN RYZIN in Journal of Child Psychology and Psychiatry, 55-10 (October 2014)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1153-1161 Titre : Adolescent deviant peer clustering as an amplifying mechanism underlying the progression from early substance use to late adolescent dependence Type de document : Texte imprimé et/ou numérique Auteurs : Mark J. VAN RYZIN, Auteur ; Thomas J. DISHION, Auteur Article en page(s) : p.1153-1161 Langues : Anglais (eng) Mots-clés : Substance dependence  deviant peer clustering  early substance use  mediation  prevention Index. décimale : PER Périodiques Résumé : Background Early substance use co-occurs with youths' self-organization into deviant peer groups in which substance use is central to social interaction. We hypothesized that the social dynamics of deviant peer groups amplify the risk of progressing from early use to later dependence, and that this influence occurs over and above escalations in use that typically accompany early substance use and membership in deviant groups. Methods Our study used a longitudinal, multimethod dataset consisting of 998 adolescents and their families. Participants were recruited from middle schools in a large metropolitan area in the Pacific Northwest. The sample was 47.3% female and ethnically diverse (42.3% European American, 29.1% African American, and 28.6% other, including biracial). We examined deviant peer clustering as a mediator between early substance use and later dependence, controlling for proximal levels of use, SES, early antisocial behavior, and parental monitoring. Tobacco, alcohol, and marijuana use were assessed at ages 12, 13, and 16–17. Past-year nicotine, alcohol, and marijuana dependence (DSM-IV) was assessed at age 19. Youth and parent reports and observational data were used to assess deviant peer clustering at age 16–17, and youth reported on antisocial behavior and parental monitoring at ages 12 and 13. Results Early substance use predicted increased likelihood of dependence on tobacco, alcohol, and marijuana by late adolescence. Deviant peer affiliation mediated these links, even when accounting for proximal levels of substance use. Conclusions Early substance use not only promotes escalations in use across adolescence but also provides entry into a deviant social context that contributes to increased risk of dependence. Our results emphasize the importance of identifying and intervening in early substance use before it becomes an organizing factor in friendship selection and interaction. Deviant peer clusters are clearly an important avenue for intervention when seeking to interrupt the progression to substance dependence. En ligne : http://dx.doi.org/10.1111/jcpp.12211 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=239 [article] Adolescent deviant peer clustering as an amplifying mechanism underlying the progression from early substance use to late adolescent dependence [Texte imprimé et/ou numérique] / Mark J. VAN RYZIN, Auteur ; Thomas J. DISHION, Auteur . - p.1153-1161. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1153-1161 Mots-clés : Substance dependence  deviant peer clustering  early substance use  mediation  prevention Index. décimale : PER Périodiques Résumé : Background Early substance use co-occurs with youths' self-organization into deviant peer groups in which substance use is central to social interaction. We hypothesized that the social dynamics of deviant peer groups amplify the risk of progressing from early use to later dependence, and that this influence occurs over and above escalations in use that typically accompany early substance use and membership in deviant groups. Methods Our study used a longitudinal, multimethod dataset consisting of 998 adolescents and their families. Participants were recruited from middle schools in a large metropolitan area in the Pacific Northwest. The sample was 47.3% female and ethnically diverse (42.3% European American, 29.1% African American, and 28.6% other, including biracial). We examined deviant peer clustering as a mediator between early substance use and later dependence, controlling for proximal levels of use, SES, early antisocial behavior, and parental monitoring. Tobacco, alcohol, and marijuana use were assessed at ages 12, 13, and 16–17. Past-year nicotine, alcohol, and marijuana dependence (DSM-IV) was assessed at age 19. Youth and parent reports and observational data were used to assess deviant peer clustering at age 16–17, and youth reported on antisocial behavior and parental monitoring at ages 12 and 13. Results Early substance use predicted increased likelihood of dependence on tobacco, alcohol, and marijuana by late adolescence. Deviant peer affiliation mediated these links, even when accounting for proximal levels of substance use. Conclusions Early substance use not only promotes escalations in use across adolescence but also provides entry into a deviant social context that contributes to increased risk of dependence. Our results emphasize the importance of identifying and intervening in early substance use before it becomes an organizing factor in friendship selection and interaction. Deviant peer clusters are clearly an important avenue for intervention when seeking to interrupt the progression to substance dependence. En ligne : http://dx.doi.org/10.1111/jcpp.12211 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=239

Classes of oppositional-defiant behavior: concurrent and predictive validity / Robert R. ALTHOFF in Journal of Child Psychology and Psychiatry, 55-10 (October 2014)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1162-1171 Titre : Classes of oppositional-defiant behavior: concurrent and predictive validity Type de document : Texte imprimé et/ou numérique Auteurs : Robert R. ALTHOFF, Auteur ; Ana V. KUNY-SLOCK, Auteur ; Frank C. VERHULST, Auteur ; James J. HUDZIAK, Auteur ; Jan VAN DER ENDE, Auteur Article en page(s) : p.1162-1171 Langues : Anglais (eng) Mots-clés : Oppositional defiant disorder  longitudinal studies  validity  Child Behavior Checklist Index. décimale : PER Périodiques Résumé : Background Oppositional defiant disorder (ODD) has components of both irritability and defiance. It remains unclear whether children with variation in these domains have different adult outcomes. This study examined the concurrent and predictive validity of classes of oppositional defiant behavior. Methods Latent class analysis was performed on the oppositional defiant problems scale of the Child Behavior Checklist in two samples, one in the US (the Achenbach Normative Sample, N = 2029) and one in the Netherlands (the Zuid-Holland Study, N = 2076). A third sample of American children (The Vermont Family Study, N = 399) was examined to determine concurrent validity with DSM diagnoses. Predictive validity over 14 years was assessed using the Zuid-Holland Study. Results Four classes of oppositional defiant problems were consistent in the two latent class analyses: No Symptoms, All Symptoms, Irritable, and Defiant. Individuals in the No Symptoms Class were rarely diagnosed concurrently with ODD or any future disorder. Individuals in the All Symptoms Class had an increased frequency of concurrent childhood diagnosis of ODD and of violence in adulthood. Subjects in the Irritable Class had low concurrent diagnosis of ODD, but increased odds of adult mood disorders. Individuals in the Defiant Class had low concurrent diagnosis of ODD, but had increased odds of violence as adults. Conclusions Only children in the All Symptoms class were likely to have a concurrent diagnosis of ODD. Although not diagnosed with ODD, children in the Irritable Class were more likely to have adult mood disorders and children in the Defiant Class were more likely to engage in violent behavior. En ligne : http://dx.doi.org/10.1111/jcpp.12233 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=239 [article] Classes of oppositional-defiant behavior: concurrent and predictive validity [Texte imprimé et/ou numérique] / Robert R. ALTHOFF, Auteur ; Ana V. KUNY-SLOCK, Auteur ; Frank C. VERHULST, Auteur ; James J. HUDZIAK, Auteur ; Jan VAN DER ENDE, Auteur . - p.1162-1171. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1162-1171 Mots-clés : Oppositional defiant disorder  longitudinal studies  validity  Child Behavior Checklist Index. décimale : PER Périodiques Résumé : Background Oppositional defiant disorder (ODD) has components of both irritability and defiance. It remains unclear whether children with variation in these domains have different adult outcomes. This study examined the concurrent and predictive validity of classes of oppositional defiant behavior. Methods Latent class analysis was performed on the oppositional defiant problems scale of the Child Behavior Checklist in two samples, one in the US (the Achenbach Normative Sample, N = 2029) and one in the Netherlands (the Zuid-Holland Study, N = 2076). A third sample of American children (The Vermont Family Study, N = 399) was examined to determine concurrent validity with DSM diagnoses. Predictive validity over 14 years was assessed using the Zuid-Holland Study. Results Four classes of oppositional defiant problems were consistent in the two latent class analyses: No Symptoms, All Symptoms, Irritable, and Defiant. Individuals in the No Symptoms Class were rarely diagnosed concurrently with ODD or any future disorder. Individuals in the All Symptoms Class had an increased frequency of concurrent childhood diagnosis of ODD and of violence in adulthood. Subjects in the Irritable Class had low concurrent diagnosis of ODD, but increased odds of adult mood disorders. Individuals in the Defiant Class had low concurrent diagnosis of ODD, but had increased odds of violence as adults. Conclusions Only children in the All Symptoms class were likely to have a concurrent diagnosis of ODD. Although not diagnosed with ODD, children in the Irritable Class were more likely to have adult mood disorders and children in the Defiant Class were more likely to engage in violent behavior. En ligne : http://dx.doi.org/10.1111/jcpp.12233 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=239

Improving child and parenting outcomes following paediatric acquired brain injury: a randomised controlled trial of Stepping Stones Triple P plus Acceptance and Commitment Therapy / Felicity L. BROWN in Journal of Child Psychology and Psychiatry, 55-10 (October 2014)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1172-1183 Titre : Improving child and parenting outcomes following paediatric acquired brain injury: a randomised controlled trial of Stepping Stones Triple P plus Acceptance and Commitment Therapy Type de document : Texte imprimé et/ou numérique Auteurs : Felicity L. BROWN, Auteur ; Koa WHITTINGHAM, Auteur ; Roslyn N. BOYD, Auteur ; Lynne MCKINLAY, Auteur ; Kate SOFRONOFF, Auteur Article en page(s) : p.1172-1183 Langues : Anglais (eng) Mots-clés : Acquired brain injury  acceptance and commitment therapy  Stepping Stones Triple P: Positive Parenting Program  behavioural and emotional functioning  parenting style  randomised controlled trial Index. décimale : PER Périodiques Résumé : Background Persistent behavioural difficulties are common following paediatric acquired brain injury (ABI). Parents and families also experience heightened stress, psychological symptoms and burden, and there is evidence of a reciprocal relationship between parent and child functioning, which may be mediated by the adoption of maladaptive parenting practices. Despite this, there is currently a paucity of research in family interventions in this population. The aim of this study was to determine the efficacy of Stepping Stones Triple P: Positive Parenting Program (SSTP), with an Acceptance and Commitment Therapy (ACT) workshop, in improving child outcomes and parenting practices following paediatric ABI. Methods Fifty-nine parents of children (mean age 7 years, SD 3 years, 1 month; 35 males, 24 females) with ABI (Traumatic injuries 58%, Tumour 17%, Encephalitis or meningitis 15%, Cardiovascular accident 7%, Hypoxia 3%) who were evidencing at least mild behaviour problems were randomly assigned to treatment or care-as-usual conditions over 10 weeks. Mixed-model repeated-measures linear regression analyses were conducted to compare conditions from pre- to postintervention on child behavioural and emotional functioning (Eyberg Child Behavior Inventory, Strengths and Difficulties Questionnaire) and dysfunctional parenting style (Parenting Scale). Assessment of maintenance of change was conducted at a 6-month follow-up. The trial was registered on Australian New Zealand Clinical Trials Registry (ID: ACTRN12610001051033, www.anzctr.org.au). Results Significant time-by-condition interactions were identified on number and intensity of child behaviour problems, child emotional symptoms and parenting laxness and overreactivity, indicating significant improvements in the treatment condition, with medium-to-large effect sizes. Most improvements were maintained at 6 months. Conclusions Group parenting interventions incorporating Triple P and ACT may be efficacious in improving child and parenting outcomes following paediatric ABI. En ligne : http://dx.doi.org/10.1111/jcpp.12227 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=239 [article] Improving child and parenting outcomes following paediatric acquired brain injury: a randomised controlled trial of Stepping Stones Triple P plus Acceptance and Commitment Therapy [Texte imprimé et/ou numérique] / Felicity L. BROWN, Auteur ; Koa WHITTINGHAM, Auteur ; Roslyn N. BOYD, Auteur ; Lynne MCKINLAY, Auteur ; Kate SOFRONOFF, Auteur . - p.1172-1183. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 55-10 (October 2014) . - p.1172-1183 Mots-clés : Acquired brain injury  acceptance and commitment therapy  Stepping Stones Triple P: Positive Parenting Program  behavioural and emotional functioning  parenting style  randomised controlled trial Index. décimale : PER Périodiques Résumé : Background Persistent behavioural difficulties are common following paediatric acquired brain injury (ABI). Parents and families also experience heightened stress, psychological symptoms and burden, and there is evidence of a reciprocal relationship between parent and child functioning, which may be mediated by the adoption of maladaptive parenting practices. Despite this, there is currently a paucity of research in family interventions in this population. The aim of this study was to determine the efficacy of Stepping Stones Triple P: Positive Parenting Program (SSTP), with an Acceptance and Commitment Therapy (ACT) workshop, in improving child outcomes and parenting practices following paediatric ABI. Methods Fifty-nine parents of children (mean age 7 years, SD 3 years, 1 month; 35 males, 24 females) with ABI (Traumatic injuries 58%, Tumour 17%, Encephalitis or meningitis 15%, Cardiovascular accident 7%, Hypoxia 3%) who were evidencing at least mild behaviour problems were randomly assigned to treatment or care-as-usual conditions over 10 weeks. Mixed-model repeated-measures linear regression analyses were conducted to compare conditions from pre- to postintervention on child behavioural and emotional functioning (Eyberg Child Behavior Inventory, Strengths and Difficulties Questionnaire) and dysfunctional parenting style (Parenting Scale). Assessment of maintenance of change was conducted at a 6-month follow-up. The trial was registered on Australian New Zealand Clinical Trials Registry (ID: ACTRN12610001051033, www.anzctr.org.au). Results Significant time-by-condition interactions were identified on number and intensity of child behaviour problems, child emotional symptoms and parenting laxness and overreactivity, indicating significant improvements in the treatment condition, with medium-to-large effect sizes. Most improvements were maintained at 6 months. Conclusions Group parenting interventions incorporating Triple P and ACT may be efficacious in improving child and parenting outcomes following paediatric ABI. En ligne : http://dx.doi.org/10.1111/jcpp.12227 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=239