Atypical Social Judgment and Sensitivity to Perceptual Cues in Autism Spectrum Disorders / Baudouin FORGEOT D'ARC in Journal of Autism and Developmental Disorders, 46-5 (May 2016)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 46-5 (May 2016) . - p.1574-1581 Titre : Atypical Social Judgment and Sensitivity to Perceptual Cues in Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Baudouin FORGEOT D'ARC, Auteur ; Franck RAMUS, Auteur ; Aline LEFEBVRE, Auteur ; Delphine BROTTIER, Auteur ; Tiziana ZALLA, Auteur ; Sanaa MOUKAWANE, Auteur ; Frédérique AMSELLEM, Auteur ; Laurence LETELLIER, Auteur ; Hugo PEYRE, Auteur ; Marie-Christine MOUREN, Auteur ; Marion LEBOYER, Auteur ; Richard DELORME, Auteur Article en page(s) : p.1574-1581 Langues : Anglais (eng) Mots-clés : Autism  Social judgment  Face processing  Social cognition  Perception Index. décimale : PER Périodiques Résumé : Evaluation of faces is an important dimension of social relationships. A degraded sensitivity to facial perceptual cues might contribute to atypical social interactions in autism spectrum disorder (ASD). The current study investigated whether face based social judgment is atypical in ASD and if so, whether it could be related to a degraded sensitivity to facial perceptual cues. Individuals with ASD (n = 33) and IQ- and age-matched controls (n = 38) were enrolled in this study. Watching a series of photographic or synthetic faces, they had to judge them for “kindness”. In synthetic stimuli, the amount of perceptual cues available could be either large or small. We observed that social judgment was atypical in the ASD group on photographic stimuli, but, contrarily to the prediction based on the degraded sensitivity hypothesis, analyses on synthetic stimuli found a similar performance and a similar effect of the amount of perceptual cues in both groups. Further studies on perceptual differences between photographs and synthetic pictures of faces might help understand atypical social judgment in ASD. En ligne : http://dx.doi.org/10.1007/s10803-014-2208-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=288 [article] Atypical Social Judgment and Sensitivity to Perceptual Cues in Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Baudouin FORGEOT D'ARC, Auteur ; Franck RAMUS, Auteur ; Aline LEFEBVRE, Auteur ; Delphine BROTTIER, Auteur ; Tiziana ZALLA, Auteur ; Sanaa MOUKAWANE, Auteur ; Frédérique AMSELLEM, Auteur ; Laurence LETELLIER, Auteur ; Hugo PEYRE, Auteur ; Marie-Christine MOUREN, Auteur ; Marion LEBOYER, Auteur ; Richard DELORME, Auteur . - p.1574-1581. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 46-5 (May 2016) . - p.1574-1581 Mots-clés : Autism  Social judgment  Face processing  Social cognition  Perception Index. décimale : PER Périodiques Résumé : Evaluation of faces is an important dimension of social relationships. A degraded sensitivity to facial perceptual cues might contribute to atypical social interactions in autism spectrum disorder (ASD). The current study investigated whether face based social judgment is atypical in ASD and if so, whether it could be related to a degraded sensitivity to facial perceptual cues. Individuals with ASD (n = 33) and IQ- and age-matched controls (n = 38) were enrolled in this study. Watching a series of photographic or synthetic faces, they had to judge them for “kindness”. In synthetic stimuli, the amount of perceptual cues available could be either large or small. We observed that social judgment was atypical in the ASD group on photographic stimuli, but, contrarily to the prediction based on the degraded sensitivity hypothesis, analyses on synthetic stimuli found a similar performance and a similar effect of the amount of perceptual cues in both groups. Further studies on perceptual differences between photographs and synthetic pictures of faces might help understand atypical social judgment in ASD. En ligne : http://dx.doi.org/10.1007/s10803-014-2208-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=288

Discriminant value of repetitive behaviors in families with autism spectrum disorder and obsessional compulsive disorder probands / A. LEFEBVRE in Autism Research, 14-11 (November 2021)  

Public ISBD [article]  inAutism Research > 14-11 (November 2021) . - p.2373-2382 Titre : Discriminant value of repetitive behaviors in families with autism spectrum disorder and obsessional compulsive disorder probands Type de document : Texte imprimé et/ou numérique Auteurs : A. LEFEBVRE, Auteur ; A. COHEN, Auteur ; A. MARUANI, Auteur ; Frédérique AMSELLEM, Auteur ; Anita BEGGIATO, Auteur ; Anouck AMESTOY, Auteur ; M. L. MOAL, Auteur ; D. UMBRICHT, Auteur ; Christopher H. CHATHAM, Auteur ; L. MURTAGH, Auteur ; Manuel P. BOUVARD, Auteur ; M. LEBOYER, Auteur ; Thomas BOURGERON, Auteur ; R. DELORME, Auteur Article en page(s) : p.2373-2382 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/complications/genetics  Cognition  Humans  Obsessive-Compulsive Disorder/genetics  habits  heritability  neurodevelopment  phenotype Index. décimale : PER Périodiques Résumé : Repetitive behaviors (RB) represent a wide spectrum of symptoms ranging from sensory-motor stereotypies to complex cognitive rituals, frequently dichotomized as low- and high-order sub-groups of symptoms. Even though these subgroups are considered as phenomenologically distinct in autism spectrum disorder (ASD) and obsessive-compulsive disorder (OCD), brain imaging and genetic studies suggest that they have common mechanisms and pathways. This discrepancy may be explained by the frequent intellectual disability reported in ASD, which blurs the RB expressivity. Given the high heritability of RB, that is, the diversity of symptoms expressed in the relatives are dependent on those expressed in their probands, we hypothesize that if RB expressed in ASD or OCD are two distinct entities, then the RB expressed in relatives will also reflect these two dimensions. We thus conduct a linear discriminant analysis on RB in both the relatives of probands with ASD and OCD and subjects from the general population (n = 1023). The discriminant analysis results in a classification of 81.1% of the controls (p? En ligne : http://dx.doi.org/10.1002/aur.2570 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450 [article] Discriminant value of repetitive behaviors in families with autism spectrum disorder and obsessional compulsive disorder probands [Texte imprimé et/ou numérique] / A. LEFEBVRE, Auteur ; A. COHEN, Auteur ; A. MARUANI, Auteur ; Frédérique AMSELLEM, Auteur ; Anita BEGGIATO, Auteur ; Anouck AMESTOY, Auteur ; M. L. MOAL, Auteur ; D. UMBRICHT, Auteur ; Christopher H. CHATHAM, Auteur ; L. MURTAGH, Auteur ; Manuel P. BOUVARD, Auteur ; M. LEBOYER, Auteur ; Thomas BOURGERON, Auteur ; R. DELORME, Auteur . - p.2373-2382. Langues : Anglais (eng) in Autism Research > 14-11 (November 2021) . - p.2373-2382 Mots-clés : Autism Spectrum Disorder/complications/genetics  Cognition  Humans  Obsessive-Compulsive Disorder/genetics  habits  heritability  neurodevelopment  phenotype Index. décimale : PER Périodiques Résumé : Repetitive behaviors (RB) represent a wide spectrum of symptoms ranging from sensory-motor stereotypies to complex cognitive rituals, frequently dichotomized as low- and high-order sub-groups of symptoms. Even though these subgroups are considered as phenomenologically distinct in autism spectrum disorder (ASD) and obsessive-compulsive disorder (OCD), brain imaging and genetic studies suggest that they have common mechanisms and pathways. This discrepancy may be explained by the frequent intellectual disability reported in ASD, which blurs the RB expressivity. Given the high heritability of RB, that is, the diversity of symptoms expressed in the relatives are dependent on those expressed in their probands, we hypothesize that if RB expressed in ASD or OCD are two distinct entities, then the RB expressed in relatives will also reflect these two dimensions. We thus conduct a linear discriminant analysis on RB in both the relatives of probands with ASD and OCD and subjects from the general population (n = 1023). The discriminant analysis results in a classification of 81.1% of the controls (p? En ligne : http://dx.doi.org/10.1002/aur.2570 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450

Episodic memory and self-awareness in Asperger Syndrome: Analysis of memory narratives / Valérie CHAPUT in Research in Autism Spectrum Disorders, 7-9 (September 2013)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 7-9 (September 2013) . - p.1062-1067 Titre : Episodic memory and self-awareness in Asperger Syndrome: Analysis of memory narratives Type de document : Texte imprimé et/ou numérique Auteurs : Valérie CHAPUT, Auteur ; Frédérique AMSELLEM, Auteur ; Isabel URDAPILLETA, Auteur ; Pauline CHASTE, Auteur ; Marion LEBOYER, Auteur ; Richard DELORME, Auteur ; Véronique GOUSSE, Auteur Article en page(s) : p.1062-1067 Langues : Anglais (eng) Mots-clés : Episodic memory  Asperger Syndrome  Self-awareness  Autonoetic consciousness  Theory of mind Index. décimale : PER Périodiques Résumé : Abstract Previous findings from researchers on individuals with Asperger Syndrome (AS) suggest peculiarities of autobiographical memory (AM). They have shown a personal episodic memory deficit in the absence of a personal semantic memory impairment. The primary aim of this study was to explore AM in individuals with AS, and more specifically to investigate the link between episodic memory, self-awareness, and autonoetic consciousness through language analysis. We asked fifteen adults with AS and fifteen age- and IQ-matched controls to recall autobiographical memories from three life periods. Recorded interviews were processed using Alceste software. We found that participants with AS recalled fewer and less-detailed episodic memories than did controls. A content analysis revealed that family-related vocabulary as well as possessive pronouns was significantly less frequent in AS interviews than in those of controls. In conclusion, our results support the hypothesis that a deficiency of episodic memory may be due to poor awareness of the self in social relationships. Reduced use of possessive pronouns may also indicate less self-investment in life experiences, which would in turn impact recall. En ligne : http://dx.doi.org/10.1016/j.rasd.2013.05.005 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=211 [article] Episodic memory and self-awareness in Asperger Syndrome: Analysis of memory narratives [Texte imprimé et/ou numérique] / Valérie CHAPUT, Auteur ; Frédérique AMSELLEM, Auteur ; Isabel URDAPILLETA, Auteur ; Pauline CHASTE, Auteur ; Marion LEBOYER, Auteur ; Richard DELORME, Auteur ; Véronique GOUSSE, Auteur . - p.1062-1067. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 7-9 (September 2013) . - p.1062-1067 Mots-clés : Episodic memory  Asperger Syndrome  Self-awareness  Autonoetic consciousness  Theory of mind Index. décimale : PER Périodiques Résumé : Abstract Previous findings from researchers on individuals with Asperger Syndrome (AS) suggest peculiarities of autobiographical memory (AM). They have shown a personal episodic memory deficit in the absence of a personal semantic memory impairment. The primary aim of this study was to explore AM in individuals with AS, and more specifically to investigate the link between episodic memory, self-awareness, and autonoetic consciousness through language analysis. We asked fifteen adults with AS and fifteen age- and IQ-matched controls to recall autobiographical memories from three life periods. Recorded interviews were processed using Alceste software. We found that participants with AS recalled fewer and less-detailed episodic memories than did controls. A content analysis revealed that family-related vocabulary as well as possessive pronouns was significantly less frequent in AS interviews than in those of controls. In conclusion, our results support the hypothesis that a deficiency of episodic memory may be due to poor awareness of the self in social relationships. Reduced use of possessive pronouns may also indicate less self-investment in life experiences, which would in turn impact recall. En ligne : http://dx.doi.org/10.1016/j.rasd.2013.05.005 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=211

Gaze direction detection in autism spectrum disorder / Baudouin FORGEOT D'ARC in Autism, 21-1 (January 2017)  

Public ISBD [article]  inAutism > 21-1 (January 2017) . - p.100-107 Titre : Gaze direction detection in autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Baudouin FORGEOT D'ARC, Auteur ; Richard DELORME, Auteur ; Tiziana ZALLA, Auteur ; Aline LEFEBVRE, Auteur ; Frédérique AMSELLEM, Auteur ; Sanaa MOUKAWANE, Auteur ; Laurence LETELLIER, Auteur ; Marion LEBOYER, Auteur ; Marie-Christine MOUREN, Auteur ; Franck RAMUS, Auteur Article en page(s) : p.100-107 Langues : Anglais (eng) Mots-clés : autism  face processing  gaze direction detection  perception  social cognition Index. décimale : PER Périodiques Résumé : Detecting where our partners direct their gaze is an important aspect of social interaction. An atypical gaze processing has been reported in autism. However, it remains controversial whether children and adults with autism spectrum disorder interpret indirect gaze direction with typical accuracy. This study investigated whether the detection of gaze direction toward an object is less accurate in autism spectrum disorder. Individuals with autism spectrum disorder (n?=?33) and intelligence quotients–matched and age-matched controls (n?=?38) were asked to watch a series of synthetic faces looking at objects, and decide which of two objects was looked at. The angle formed by the two possible targets and the face varied following an adaptive procedure, in order to determine individual thresholds. We found that gaze direction detection was less accurate in autism spectrum disorder than in control participants. Our results suggest that the precision of gaze following may be one of the altered processes underlying social interaction difficulties in autism spectrum disorder. En ligne : http://dx.doi.org/10.1177/1362361316630880 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=297 [article] Gaze direction detection in autism spectrum disorder [Texte imprimé et/ou numérique] / Baudouin FORGEOT D'ARC, Auteur ; Richard DELORME, Auteur ; Tiziana ZALLA, Auteur ; Aline LEFEBVRE, Auteur ; Frédérique AMSELLEM, Auteur ; Sanaa MOUKAWANE, Auteur ; Laurence LETELLIER, Auteur ; Marion LEBOYER, Auteur ; Marie-Christine MOUREN, Auteur ; Franck RAMUS, Auteur . - p.100-107. Langues : Anglais (eng) in Autism > 21-1 (January 2017) . - p.100-107 Mots-clés : autism  face processing  gaze direction detection  perception  social cognition Index. décimale : PER Périodiques Résumé : Detecting where our partners direct their gaze is an important aspect of social interaction. An atypical gaze processing has been reported in autism. However, it remains controversial whether children and adults with autism spectrum disorder interpret indirect gaze direction with typical accuracy. This study investigated whether the detection of gaze direction toward an object is less accurate in autism spectrum disorder. Individuals with autism spectrum disorder (n?=?33) and intelligence quotients–matched and age-matched controls (n?=?38) were asked to watch a series of synthetic faces looking at objects, and decide which of two objects was looked at. The angle formed by the two possible targets and the face varied following an adaptive procedure, in order to determine individual thresholds. We found that gaze direction detection was less accurate in autism spectrum disorder than in control participants. Our results suggest that the precision of gaze following may be one of the altered processes underlying social interaction difficulties in autism spectrum disorder. En ligne : http://dx.doi.org/10.1177/1362361316630880 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=297

Gender differences in autism spectrum disorders: Divergence among specific core symptoms / Anita BEGGIATO in Autism Research, 10-4 (April 2017)  

Public ISBD [article]  inAutism Research > 10-4 (April 2017) . - p.680-689 Titre : Gender differences in autism spectrum disorders: Divergence among specific core symptoms Type de document : Texte imprimé et/ou numérique Auteurs : Anita BEGGIATO, Auteur ; Hugo PEYRE, Auteur ; Anna MARUANI, Auteur ; Isabelle SCHEID, Auteur ; Maria RASTAM, Auteur ; Frédérique AMSELLEM, Auteur ; Carina I. GILLBERG, Auteur ; Marion LEBOYER, Auteur ; Thomas BOURGERON, Auteur ; Christopher GILLBERG, Auteur ; Richard DELORME, Auteur Article en page(s) : p.680-689 Langues : Anglais (eng) Mots-clés : autism spectrum disorders  sex  gender  autism diagnosis interview-revised Index. décimale : PER Périodiques Résumé : Community-based studies have consistently shown a sex ratio heavily skewed towards males in autism spectrum disorders (ASD). The factors underlying this predominance of males are largely unknown, but the way girls score on standardized categorical diagnostic tools might account for the underrecognition of ASD in girls. Despite the existence of different norms for boys and girls with ASD on several major screening tests, the algorithm of the Autism Diagnosis Interview-Revised (ADI-R) has not been reformulated. The aim of our study was to investigate which ADI-R items discriminate between males and females, and to evaluate their weighting in the final diagnosis of autism. We then conducted discriminant analysis (DA) on a sample of 594 probands including 129 females with ASD, recruited by the Paris Autism Research International Sibpair (PARIS) Study. A replication analysis was run on an independent sample of 1716 probands including 338 females with ASD, recruited through the Autism Genetics Resource Exchange (AGRE) program. Entering the raw scores for all ADI-R items as independent variables, the DA correctly classified 78.9% of males and 72.9% of females (P? En ligne : http://dx.doi.org/10.1002/aur.1715 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=307 [article] Gender differences in autism spectrum disorders: Divergence among specific core symptoms [Texte imprimé et/ou numérique] / Anita BEGGIATO, Auteur ; Hugo PEYRE, Auteur ; Anna MARUANI, Auteur ; Isabelle SCHEID, Auteur ; Maria RASTAM, Auteur ; Frédérique AMSELLEM, Auteur ; Carina I. GILLBERG, Auteur ; Marion LEBOYER, Auteur ; Thomas BOURGERON, Auteur ; Christopher GILLBERG, Auteur ; Richard DELORME, Auteur . - p.680-689. Langues : Anglais (eng) in Autism Research > 10-4 (April 2017) . - p.680-689 Mots-clés : autism spectrum disorders  sex  gender  autism diagnosis interview-revised Index. décimale : PER Périodiques Résumé : Community-based studies have consistently shown a sex ratio heavily skewed towards males in autism spectrum disorders (ASD). The factors underlying this predominance of males are largely unknown, but the way girls score on standardized categorical diagnostic tools might account for the underrecognition of ASD in girls. Despite the existence of different norms for boys and girls with ASD on several major screening tests, the algorithm of the Autism Diagnosis Interview-Revised (ADI-R) has not been reformulated. The aim of our study was to investigate which ADI-R items discriminate between males and females, and to evaluate their weighting in the final diagnosis of autism. We then conducted discriminant analysis (DA) on a sample of 594 probands including 129 females with ASD, recruited by the Paris Autism Research International Sibpair (PARIS) Study. A replication analysis was run on an independent sample of 1716 probands including 338 females with ASD, recruited through the Autism Genetics Resource Exchange (AGRE) program. Entering the raw scores for all ADI-R items as independent variables, the DA correctly classified 78.9% of males and 72.9% of females (P? En ligne : http://dx.doi.org/10.1002/aur.1715 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=307

Tackling hypo and hyper sensory processing heterogeneity in autism: From clinical stratification to genetic pathways / Julian TILLMANN ; Freddy CLIQUET ; Frédérique AMSELLEM ; Anna MARUANI ; Claire LEBLOND ; Anita BEGGIATO ; David GERMANAUD ; Anouck AMESTOY ; Myriam LY-LE MOAL ; Daniel UMBRICHT ; Christopher CHATHAM ; Lorraine MURTAGH ; Manuel BOUVARD ; Marion LEBOYER ; Tony CHARMAN ; Thomas BOURGERON ; Richard DELORME ; Guillaume DUMAS ; EU-AIMS LEAP Group in Autism Research, 16-2 (February 2023)  

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