Dépouillements

How is psychological wellbeing experienced by autistic women? Challenges and protective factors: A meta-synthesis / Natalie YAU in Research in Autism Spectrum Disorders, 102 (April 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 102 (April 2023) . - p.102101 Titre : How is psychological wellbeing experienced by autistic women? Challenges and protective factors: A meta-synthesis Type de document : Texte imprimé et/ou numérique Auteurs : Natalie YAU, Auteur ; Sonia ANDERSON, Auteur ; Ian C. SMITH, Auteur Article en page(s) : p.102101 Langues : Anglais (eng) Mots-clés : Women  Autism  Mental Health  Psychological Wellbeing Index. décimale : PER Périodiques Résumé : Background Autistic women are at higher risks of experiencing mental health difficulties and suicidal behaviours than the general population. However, there are barriers to diagnostic assessments and mental health support reported by autistic women. To date, there is little research into how psychological wellness is experienced by autistic women. Therefore, the aim of this meta-synthesis was to explore this. Method A systematic literature review of existing qualitative studies was carried out. Twelve papers met the inclusion criteria for this review; the findings of which were collated and synthesised using a seven-step meta-ethnographic approach from which three themes emerged. Results Three themes were generated from the 12 qualitative studies: (1) ''I tend to fall between the cracks": misunderstood and ostracised; (2) "The hidden hurt"; and (3) having to meet the expectations of others. There are important findings from the meta-synthesis which suggest there are increased risks of exploitation for autistic women. Furthermore, social camouflaging in addition to societal, cultural, and gendered expectations can have detrimental influences on psychological wellbeing for autistic women. However, mutual acceptance, belonging, and support were identified as protective factors of psychological wellbeing. Conclusions Increased knowledge and training for professionals supporting autistic women is needed, particularly during different life stages such as the peri- and postnatal period and the menopause. There is also a need to promote better awareness of safe relationships to reduce risks of abuse and exploitation for autistic women. Adaptations to communication, cognitive and sensory challenges, and psychological therapy are also suggested. En ligne : https://doi.org/10.1016/j.rasd.2022.102101 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=501 [article] How is psychological wellbeing experienced by autistic women? Challenges and protective factors: A meta-synthesis [Texte imprimé et/ou numérique] / Natalie YAU, Auteur ; Sonia ANDERSON, Auteur ; Ian C. SMITH, Auteur . - p.102101. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 102 (April 2023) . - p.102101 Mots-clés : Women  Autism  Mental Health  Psychological Wellbeing Index. décimale : PER Périodiques Résumé : Background Autistic women are at higher risks of experiencing mental health difficulties and suicidal behaviours than the general population. However, there are barriers to diagnostic assessments and mental health support reported by autistic women. To date, there is little research into how psychological wellness is experienced by autistic women. Therefore, the aim of this meta-synthesis was to explore this. Method A systematic literature review of existing qualitative studies was carried out. Twelve papers met the inclusion criteria for this review; the findings of which were collated and synthesised using a seven-step meta-ethnographic approach from which three themes emerged. Results Three themes were generated from the 12 qualitative studies: (1) ''I tend to fall between the cracks": misunderstood and ostracised; (2) "The hidden hurt"; and (3) having to meet the expectations of others. There are important findings from the meta-synthesis which suggest there are increased risks of exploitation for autistic women. Furthermore, social camouflaging in addition to societal, cultural, and gendered expectations can have detrimental influences on psychological wellbeing for autistic women. However, mutual acceptance, belonging, and support were identified as protective factors of psychological wellbeing. Conclusions Increased knowledge and training for professionals supporting autistic women is needed, particularly during different life stages such as the peri- and postnatal period and the menopause. There is also a need to promote better awareness of safe relationships to reduce risks of abuse and exploitation for autistic women. Adaptations to communication, cognitive and sensory challenges, and psychological therapy are also suggested. En ligne : https://doi.org/10.1016/j.rasd.2022.102101 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=501

The associations of theory of mind with both general and theory-of-mind-related social interaction in children with autism spectrum disorder / Shih-Yao MAO in Research in Autism Spectrum Disorders, 102 (April 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 102 (April 2023) . - p.102107 Titre : The associations of theory of mind with both general and theory-of-mind-related social interaction in children with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Shih-Yao MAO, Auteur ; Hsiu Man CHIU, Auteur ; Yen-Ting YU, Auteur ; Kuan-Lin CHEN, Auteur Article en page(s) : p.102107 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Social interaction  Theory of mind  Symptom severity  Verbal comprehension Index. décimale : PER Périodiques Résumé : Background Theory of mind (ToM) appears to be associated with social interaction impairment in children with autism spectrum disorder (ASD). However, limited studies have examined the relationship between ToM and social interaction in children with ASD by separating social interaction into general and ToM-related categories. Therefore, this study examined whether ToM was a predictor of general and ToM-related social interaction in children with ASD, controlling for symptom severity and verbal comprehension. Method A total of 135 children with ASD (mean age: 8.41 + 1.73 years old) and their caregivers participated. Children were assessed with the Theory of Mind Task Battery, Vineland Adaptive Behavior Scales-Socialization domain, and Interactive Scale of Social Skills Questionnaire-Parent form. Results The correlational findings revealed moderate correlations of ToM with general and ToM-related social interaction (r = 0.557 and r = 0.464, p < .001). Symptom severity and verbal comprehension were also moderately correlated with general (r = ?0.584 and r = 0.497, all p < .001) and ToM-related (r = ?0.507 and r = 0.491, all p < .001) social interaction. The two hierarchical regression models further showed that ToM predicted both general (p = .002) and ToM-related social interaction (p = .038) when symptom severity and verbal comprehension were controlled for. Conclusions Conclusively, ToM was found to be a significant predictor of both general social interaction and ToM-related social interaction. The findings of this study highlight the importance of ToM in planning assessment and intervention for general and ToM-related social interaction in children with ASD. En ligne : https://doi.org/10.1016/j.rasd.2023.102107 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=501 [article] The associations of theory of mind with both general and theory-of-mind-related social interaction in children with autism spectrum disorder [Texte imprimé et/ou numérique] / Shih-Yao MAO, Auteur ; Hsiu Man CHIU, Auteur ; Yen-Ting YU, Auteur ; Kuan-Lin CHEN, Auteur . - p.102107. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 102 (April 2023) . - p.102107 Mots-clés : Autism spectrum disorders  Social interaction  Theory of mind  Symptom severity  Verbal comprehension Index. décimale : PER Périodiques Résumé : Background Theory of mind (ToM) appears to be associated with social interaction impairment in children with autism spectrum disorder (ASD). However, limited studies have examined the relationship between ToM and social interaction in children with ASD by separating social interaction into general and ToM-related categories. Therefore, this study examined whether ToM was a predictor of general and ToM-related social interaction in children with ASD, controlling for symptom severity and verbal comprehension. Method A total of 135 children with ASD (mean age: 8.41 + 1.73 years old) and their caregivers participated. Children were assessed with the Theory of Mind Task Battery, Vineland Adaptive Behavior Scales-Socialization domain, and Interactive Scale of Social Skills Questionnaire-Parent form. Results The correlational findings revealed moderate correlations of ToM with general and ToM-related social interaction (r = 0.557 and r = 0.464, p < .001). Symptom severity and verbal comprehension were also moderately correlated with general (r = ?0.584 and r = 0.497, all p < .001) and ToM-related (r = ?0.507 and r = 0.491, all p < .001) social interaction. The two hierarchical regression models further showed that ToM predicted both general (p = .002) and ToM-related social interaction (p = .038) when symptom severity and verbal comprehension were controlled for. Conclusions Conclusively, ToM was found to be a significant predictor of both general social interaction and ToM-related social interaction. The findings of this study highlight the importance of ToM in planning assessment and intervention for general and ToM-related social interaction in children with ASD. En ligne : https://doi.org/10.1016/j.rasd.2023.102107 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=501

Assessing 'coherence' in the spoken narrative accounts of autistic people: A systematic scoping review / Anna HARVEY in Research in Autism Spectrum Disorders, 102 (April 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 102 (April 2023) . - p.102108 Titre : Assessing 'coherence' in the spoken narrative accounts of autistic people: A systematic scoping review Type de document : Texte imprimé et/ou numérique Auteurs : Anna HARVEY, Auteur ; Helen SPICER-CAIN, Auteur ; Nicola BOTTING, Auteur ; Gemma RYAN, Auteur ; Lucy HENRY, Auteur Article en page(s) : p.102108 Langues : Anglais (eng) Mots-clés : Autism  Narrative  Coherence  Macrostructure  Story grammar Index. décimale : PER Périodiques Résumé : Background The ability to produce a well-structured, coherent narrative account is essential for successful everyday communication. Research suggests that autistic people may find this challenging, and that narrative assessment can reveal pragmatic difficulties in this population that are missed on sentence-level tasks. Previous studies have used different methodologies to assess spoken narrative skills in autism. This review systematically examined these approaches and considered their utility for assessing narrative coherence. Method Keyword database searches were conducted, with records screened by two independent reviewers. Eligible studies (n = 59) included specified frameworks for evaluating structure/coherence in spoken narrative accounts by autistic participants of any age. Studies were categorised according to the type of narrative scoring scheme used, and strengths and limitations were considered. Results Over 80% of included articles reported observational cross-sectional studies, with participants generally matched on age and cognitive ability with non-autistic comparison groups. The most common approaches involved coding key elements of narrative structure ('story grammar') or scoring the inclusion of pre-determined 'main events'. Alternative frameworks included 'holistic' rating scales and subjective quality judgements by listeners. Some studies focused specifically on 'coherence', measuring diverse aspects such as causal connectedness and incongruence. Scoring criteria varied for each type of framework. Conclusions Findings indicated that solely assessing story structure ignores important features contributing to the coherence of spoken narrative accounts. Recommendations are that future research consider the following elements: (1) context, (2) chronology, (3) causality, (4) congruence, (5) characters (cognition/emotion), and (6) cohesion; and scoring methods should include rating scales to obtain sufficiently detailed information about narrative quality. En ligne : https://doi.org/10.1016/j.rasd.2023.102108 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=501 [article] Assessing 'coherence' in the spoken narrative accounts of autistic people: A systematic scoping review [Texte imprimé et/ou numérique] / Anna HARVEY, Auteur ; Helen SPICER-CAIN, Auteur ; Nicola BOTTING, Auteur ; Gemma RYAN, Auteur ; Lucy HENRY, Auteur . - p.102108. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 102 (April 2023) . - p.102108 Mots-clés : Autism  Narrative  Coherence  Macrostructure  Story grammar Index. décimale : PER Périodiques Résumé : Background The ability to produce a well-structured, coherent narrative account is essential for successful everyday communication. Research suggests that autistic people may find this challenging, and that narrative assessment can reveal pragmatic difficulties in this population that are missed on sentence-level tasks. Previous studies have used different methodologies to assess spoken narrative skills in autism. This review systematically examined these approaches and considered their utility for assessing narrative coherence. Method Keyword database searches were conducted, with records screened by two independent reviewers. Eligible studies (n = 59) included specified frameworks for evaluating structure/coherence in spoken narrative accounts by autistic participants of any age. Studies were categorised according to the type of narrative scoring scheme used, and strengths and limitations were considered. Results Over 80% of included articles reported observational cross-sectional studies, with participants generally matched on age and cognitive ability with non-autistic comparison groups. The most common approaches involved coding key elements of narrative structure ('story grammar') or scoring the inclusion of pre-determined 'main events'. Alternative frameworks included 'holistic' rating scales and subjective quality judgements by listeners. Some studies focused specifically on 'coherence', measuring diverse aspects such as causal connectedness and incongruence. Scoring criteria varied for each type of framework. Conclusions Findings indicated that solely assessing story structure ignores important features contributing to the coherence of spoken narrative accounts. Recommendations are that future research consider the following elements: (1) context, (2) chronology, (3) causality, (4) congruence, (5) characters (cognition/emotion), and (6) cohesion; and scoring methods should include rating scales to obtain sufficiently detailed information about narrative quality. En ligne : https://doi.org/10.1016/j.rasd.2023.102108 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=501

The impact of COVID-19 on sleep for autistic children: A systematic review / Samantha LEWIS in Research in Autism Spectrum Disorders, 102 (April 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 102 (April 2023) . - p.102110 Titre : The impact of COVID-19 on sleep for autistic children: A systematic review Type de document : Texte imprimé et/ou numérique Auteurs : Samantha LEWIS, Auteur ; Nicole PAPADOPOULOS, Auteur ; Ana MANTILLA, Auteur ; Harriet HISCOCK, Auteur ; Moira WHELAN, Auteur ; Jane MCGILLIVRAY, Auteur ; Nicole RINEHART, Auteur Article en page(s) : p.102110 Langues : Anglais (eng) Mots-clés : Autism  Children  Sleep  COVID-19  Telehealth Index. décimale : PER Périodiques Résumé : Background Up to 80% of children with autism experience behavioural sleep problems, predominantly relating to bedtime resistance, sleep anxiety, sleep dysregulation, and shorter duration, which are associated with increased autistic symptom expression and emotional and behavioural difficulties. Researchers predicted the COVID-19 pandemic would worsen sleep and behavioural difficulties for autistic children, due to their need for routine and certainty. This systematic review is the first to focus on delineating the role of sleep disturbance in exacerbating autistic symptoms and internalising and externalising behaviours during the pandemic. Method In this PROSPERO registered systematic review, we aggregated and synthesised findings from empirical studies from 2020 onwards that included children with autism and examined sleep outcomes, using narrative and framework synthesis due to the variety of methods and designs employed. We identified additional relevant themes through inductive thematic analysis. Results Seventy-one studies met the search criteria, and we selected seventeen for review following screening and quality assessment. These studies reported mixed findings; with strongest support for worsening of sleep problems typically experienced by autistic children, including difficulties with sleep regulation and shorter sleep duration. Further, sleep problems were associated with increased expression of autistic characteristics. Conclusions Preliminary findings of worsening sleep and increased autistic characteristics for autistic children throughout the COVID-19 pandemic highlight the need for ongoing, accessible and flexible service provision during exposure to environmental stressors. We propose that behavioural sleep interventions are well suited to telehealth adaptation and play an important role in supporting families when in-person treatment for sleep problems is not possible. En ligne : https://doi.org/10.1016/j.rasd.2023.102110 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=501 [article] The impact of COVID-19 on sleep for autistic children: A systematic review [Texte imprimé et/ou numérique] / Samantha LEWIS, Auteur ; Nicole PAPADOPOULOS, Auteur ; Ana MANTILLA, Auteur ; Harriet HISCOCK, Auteur ; Moira WHELAN, Auteur ; Jane MCGILLIVRAY, Auteur ; Nicole RINEHART, Auteur . - p.102110. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 102 (April 2023) . - p.102110 Mots-clés : Autism  Children  Sleep  COVID-19  Telehealth Index. décimale : PER Périodiques Résumé : Background Up to 80% of children with autism experience behavioural sleep problems, predominantly relating to bedtime resistance, sleep anxiety, sleep dysregulation, and shorter duration, which are associated with increased autistic symptom expression and emotional and behavioural difficulties. Researchers predicted the COVID-19 pandemic would worsen sleep and behavioural difficulties for autistic children, due to their need for routine and certainty. This systematic review is the first to focus on delineating the role of sleep disturbance in exacerbating autistic symptoms and internalising and externalising behaviours during the pandemic. Method In this PROSPERO registered systematic review, we aggregated and synthesised findings from empirical studies from 2020 onwards that included children with autism and examined sleep outcomes, using narrative and framework synthesis due to the variety of methods and designs employed. We identified additional relevant themes through inductive thematic analysis. Results Seventy-one studies met the search criteria, and we selected seventeen for review following screening and quality assessment. These studies reported mixed findings; with strongest support for worsening of sleep problems typically experienced by autistic children, including difficulties with sleep regulation and shorter sleep duration. Further, sleep problems were associated with increased expression of autistic characteristics. Conclusions Preliminary findings of worsening sleep and increased autistic characteristics for autistic children throughout the COVID-19 pandemic highlight the need for ongoing, accessible and flexible service provision during exposure to environmental stressors. We propose that behavioural sleep interventions are well suited to telehealth adaptation and play an important role in supporting families when in-person treatment for sleep problems is not possible. En ligne : https://doi.org/10.1016/j.rasd.2023.102110 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=501

Intolerance-of-uncertainty and anxiety as serial mediators between emotional dysregulation and repetitive patterns in young people with autism / Carmen BENEYTEZ in Research in Autism Spectrum Disorders, 102 (April 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 102 (April 2023) . - p.102116 Titre : Intolerance-of-uncertainty and anxiety as serial mediators between emotional dysregulation and repetitive patterns in young people with autism Type de document : Texte imprimé et/ou numérique Auteurs : Carmen BENEYTEZ, Auteur Article en page(s) : p.102116 Langues : Anglais (eng) Mots-clés : Anxiety  Transdiagnostic factors  Repetitive and restricted patterns  Emotional well-being  Emotional dysregulation  Uncertainty Index. décimale : PER Périodiques Résumé : Background Previous research on anxiety in autism has largely focused on direct relationships. The overlap between symptoms of autism and anxiety and the influence that transdiagnostic variables exert on them make necessary explanatory models that consider all the factors involved in the triggering and maintenance of anxiety and its expression through typical features of autism. Method The main objective of this study was to examine the relationship between two transdiagnostic mechanisms (emotional dysregulation (ED) and intolerance of uncertainty (IU)) and repetitive and restricted patterns (RRP) and the role that anxiety has in this relationship. IU and anxiety were configured as serial mediators between ED and two subtypes of restricted patterns: sameness behaviors and sensory over-responsiveness. The sample included 87 children and adolescents on the autism spectrum aged from 6 to 18 years. Variables were assessed using a number of well-known outcome measures. Results The results of our simple mediation model show that the indirect effect of anxiety is higher between transdiagnostic variables and sensory over-responsiveness than between transdiagnostic variables and sameness behaviors. Our model suggests that ED predicts sameness behaviors and sensory over-responsiveness through the serial indirect effect of IU and anxiety. Conclusions Our findings contribute to clarify the role that anxiety and transdiagnostic mechanisms may play on RRP and may have important implications for the assessment and treatment of anxiety in people with ASD. En ligne : https://doi.org/10.1016/j.rasd.2023.102116 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=501 [article] Intolerance-of-uncertainty and anxiety as serial mediators between emotional dysregulation and repetitive patterns in young people with autism [Texte imprimé et/ou numérique] / Carmen BENEYTEZ, Auteur . - p.102116. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 102 (April 2023) . - p.102116 Mots-clés : Anxiety  Transdiagnostic factors  Repetitive and restricted patterns  Emotional well-being  Emotional dysregulation  Uncertainty Index. décimale : PER Périodiques Résumé : Background Previous research on anxiety in autism has largely focused on direct relationships. The overlap between symptoms of autism and anxiety and the influence that transdiagnostic variables exert on them make necessary explanatory models that consider all the factors involved in the triggering and maintenance of anxiety and its expression through typical features of autism. Method The main objective of this study was to examine the relationship between two transdiagnostic mechanisms (emotional dysregulation (ED) and intolerance of uncertainty (IU)) and repetitive and restricted patterns (RRP) and the role that anxiety has in this relationship. IU and anxiety were configured as serial mediators between ED and two subtypes of restricted patterns: sameness behaviors and sensory over-responsiveness. The sample included 87 children and adolescents on the autism spectrum aged from 6 to 18 years. Variables were assessed using a number of well-known outcome measures. Results The results of our simple mediation model show that the indirect effect of anxiety is higher between transdiagnostic variables and sensory over-responsiveness than between transdiagnostic variables and sameness behaviors. Our model suggests that ED predicts sameness behaviors and sensory over-responsiveness through the serial indirect effect of IU and anxiety. Conclusions Our findings contribute to clarify the role that anxiety and transdiagnostic mechanisms may play on RRP and may have important implications for the assessment and treatment of anxiety in people with ASD. En ligne : https://doi.org/10.1016/j.rasd.2023.102116 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=501

Evidence map of Spanish language parent- and self-report screening and diagnostic tools for autism spectrum disorder / Michaela DUBAY in Research in Autism Spectrum Disorders, 102 (April 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 102 (April 2023) . - p.102117 Titre : Evidence map of Spanish language parent- and self-report screening and diagnostic tools for autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Michaela DUBAY, Auteur ; Helen LEE, Auteur ; Ruben PALOMO, Auteur Article en page(s) : p.102117 Langues : Anglais (eng) Mots-clés : ASD  Assessment  Translation  Cultural adaptation  Empirical testing Index. décimale : PER Périodiques Résumé : Background With increasing interests in identification and diagnosis of autism spectrum disorder (ASD) across the world, a number of screening and diagnostic tools have been developed and translated from one language to another in varying qualities. In particular, many tools have been made available in Spanish to meet the needs of the world?s large Spanish-speaking populations. Critical examination of such Spanish language tools, in the areas of development and translation as well as empirical testing, is necessary to determine the quality of these tools, including their validity and reliability in the target population. The aim of the present review is to provide a comprehensive evidence map of screening and diagnostic tools for ASD in Spanish, especially with regards to the aspects of development/translation and empirical testing. Method A total of 48 Spanish versions of 21 instruments met study criteria for analysis after conducting multiple searches through nine key databases, grey literature, and by contacting authors, translators, and publishers. Results Results showed that a significant number of translations lacked translational process details in published locations and a majority of the studies used a traditional forward-backward approach rather than cultural adaptation procedures. About half of the translations did not provide necessary empirical evidence to support clinical utility of their translated tool. Conclusions Future studies are recommended to take more rigorous, culturally adaptive translational approach and test instruments in local populations to ensure their psychometric validities. En ligne : https://doi.org/10.1016/j.rasd.2023.102117 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=501 [article] Evidence map of Spanish language parent- and self-report screening and diagnostic tools for autism spectrum disorder [Texte imprimé et/ou numérique] / Michaela DUBAY, Auteur ; Helen LEE, Auteur ; Ruben PALOMO, Auteur . - p.102117. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 102 (April 2023) . - p.102117 Mots-clés : ASD  Assessment  Translation  Cultural adaptation  Empirical testing Index. décimale : PER Périodiques Résumé : Background With increasing interests in identification and diagnosis of autism spectrum disorder (ASD) across the world, a number of screening and diagnostic tools have been developed and translated from one language to another in varying qualities. In particular, many tools have been made available in Spanish to meet the needs of the world?s large Spanish-speaking populations. Critical examination of such Spanish language tools, in the areas of development and translation as well as empirical testing, is necessary to determine the quality of these tools, including their validity and reliability in the target population. The aim of the present review is to provide a comprehensive evidence map of screening and diagnostic tools for ASD in Spanish, especially with regards to the aspects of development/translation and empirical testing. Method A total of 48 Spanish versions of 21 instruments met study criteria for analysis after conducting multiple searches through nine key databases, grey literature, and by contacting authors, translators, and publishers. Results Results showed that a significant number of translations lacked translational process details in published locations and a majority of the studies used a traditional forward-backward approach rather than cultural adaptation procedures. About half of the translations did not provide necessary empirical evidence to support clinical utility of their translated tool. Conclusions Future studies are recommended to take more rigorous, culturally adaptive translational approach and test instruments in local populations to ensure their psychometric validities. En ligne : https://doi.org/10.1016/j.rasd.2023.102117 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=501

Differences in speech articulatory timing and associations with pragmatic language ability in autism / Joseph C. Y. LAU in Research in Autism Spectrum Disorders, 102 (April 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 102 (April 2023) . - p.102118 Titre : Differences in speech articulatory timing and associations with pragmatic language ability in autism Type de document : Texte imprimé et/ou numérique Auteurs : Joseph C. Y. LAU, Auteur ; Molly LOSH, Auteur ; Marisha SPEIGHTS, Auteur Article en page(s) : p.102118 Langues : Anglais (eng) Mots-clés : ASD  Speech articulation  Articulatory timing  Prosody  Pragmatics Index. décimale : PER Périodiques Résumé : Background Speech articulation difficulties have not traditionally been considered to be a feature of Autism Spectrum Disorder (ASD). In contrast, speech prosodic differences have been widely reported in ASD, and may even be expressed in subtle form among clinically unaffected first-degree relatives, representing the expression of underlying genetic liability. Some evidence has challenged this traditional dichotomy, suggesting that differences in speech articulatory mechanisms may be evident in ASD, and potentially related to perceived prosodic differences. Clinical measurement of articulatory skills has traditionally been phoneme-based, rather than by acoustic measurement of motor control. Subtle differences in articulatory/motor control, prosodic characteristics (acoustic), and pragmatic language ability (linguistic) may each be contributors to differences perceived by listeners, but the interrelationship is unclear. In this study, we examined the articulatory aspects of this relationship, in speech samples from individuals with ASD and their parents during narration. Method Using Speechmark® analysis, we examined articulatory landmarks, fine-grained representations of articulatory timing as series of laryngeal and vocal-tract gestures pertaining to prosodic elements crucial for conveying pragmatic information. Results Results revealed articulatory timing differences in individuals with ASD but not their parents, suggesting that although potentially not influenced by broader genetic liability to ASD, subtle articulatory differences may indeed be evident in ASD as the recent literature indicates. A follow-up path analysis detected associations between articulatory timing differences and prosody, and subsequently, pragmatic language ability. Conclusion Together, results suggest a complex relationship where subtle differences in articulatory timing may result in atypical acoustic signals, and serve as a distal mechanistic contributor to pragmatic language ability ASD. En ligne : https://doi.org/10.1016/j.rasd.2023.102118 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=501 [article] Differences in speech articulatory timing and associations with pragmatic language ability in autism [Texte imprimé et/ou numérique] / Joseph C. Y. LAU, Auteur ; Molly LOSH, Auteur ; Marisha SPEIGHTS, Auteur . - p.102118. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 102 (April 2023) . - p.102118 Mots-clés : ASD  Speech articulation  Articulatory timing  Prosody  Pragmatics Index. décimale : PER Périodiques Résumé : Background Speech articulation difficulties have not traditionally been considered to be a feature of Autism Spectrum Disorder (ASD). In contrast, speech prosodic differences have been widely reported in ASD, and may even be expressed in subtle form among clinically unaffected first-degree relatives, representing the expression of underlying genetic liability. Some evidence has challenged this traditional dichotomy, suggesting that differences in speech articulatory mechanisms may be evident in ASD, and potentially related to perceived prosodic differences. Clinical measurement of articulatory skills has traditionally been phoneme-based, rather than by acoustic measurement of motor control. Subtle differences in articulatory/motor control, prosodic characteristics (acoustic), and pragmatic language ability (linguistic) may each be contributors to differences perceived by listeners, but the interrelationship is unclear. In this study, we examined the articulatory aspects of this relationship, in speech samples from individuals with ASD and their parents during narration. Method Using Speechmark® analysis, we examined articulatory landmarks, fine-grained representations of articulatory timing as series of laryngeal and vocal-tract gestures pertaining to prosodic elements crucial for conveying pragmatic information. Results Results revealed articulatory timing differences in individuals with ASD but not their parents, suggesting that although potentially not influenced by broader genetic liability to ASD, subtle articulatory differences may indeed be evident in ASD as the recent literature indicates. A follow-up path analysis detected associations between articulatory timing differences and prosody, and subsequently, pragmatic language ability. Conclusion Together, results suggest a complex relationship where subtle differences in articulatory timing may result in atypical acoustic signals, and serve as a distal mechanistic contributor to pragmatic language ability ASD. En ligne : https://doi.org/10.1016/j.rasd.2023.102118 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=501

Analysis of urinary 8-hydroxy-2-deoxyguanosine as a biomarker of oxidative DNA damage in pediatric children with autism spectrum disorder / Eman Ahmed ZAKY in Research in Autism Spectrum Disorders, 102 (April 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 102 (April 2023) . - p.102129 Titre : Analysis of urinary 8-hydroxy-2-deoxyguanosine as a biomarker of oxidative DNA damage in pediatric children with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Eman Ahmed ZAKY, Auteur ; Salwa Amin Abd ELHAMEED, Auteur ; Shimaa Mostafa ISMAIL, Auteur ; Nourhan Moustafa ELDAMER, Auteur ; Asmaa Wafeeq ABDELAZIZ, Auteur Article en page(s) : p.102129 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Oxidative stress  Oxidative DNA damage  8-hydroxy-2?-deoxyguanosine Index. décimale : PER Périodiques Résumé : Background Autism spectrum disorder (ASD) is a neurodevelopmental condition that manifests itself in infancy. While genetic factors are the most important in its development, numerous other variables, as neurological, environmental, and immunological factors, have been found. The imbalance of oxidants and antioxidants has a role in the pathogenesis of ASD. We evaluated children with autism for the presence of oxidative DNA damage (ODD) biomarker 8-hydroxy-2-deoxyguanosine (8OHdG) and assessed its association with disease severity, and omega 3 supplementation. Methods A total of 102 children (51 children with ASD and 51 typically developed children) were recruited for this observational controlled cross-sectional study. Childhood Autism Rating Scale (CARS) was used to measure the severity of autism. The urinary 8-OH-dG was determined by using the ELISA method. Results urinary 8-OH-dG/creatinine levels were significantly higher in children with autism compared to their healthy peers (P < 0.001) with positive significant association with disease duration, severity, and positive family history (P = 0.03, P < 0.001, P = 0.03 respectively). Using a cut-of value of > 1.7, urinary 8-OHdG/creatinine ratios showed sensitivity and specificity of 80.39% and 74.51% respectively as a good discriminating power between normal and autistic children. Additionally, statistically lower significant urinary 8-OHdG/creatinine was found among ASD children received omega 3 than those who didn?t receive it (p < 0.001). Conclusion Increased urinary 8-OHdG/creatinine levels indicate an important role of oxidative DNA damage in ASD, and its significant higher level in ASD children with severe social impairment may be used as a potential non-invasive biomarker for disease severity. En ligne : https://doi.org/10.1016/j.rasd.2023.102129 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=501 [article] Analysis of urinary 8-hydroxy-2-deoxyguanosine as a biomarker of oxidative DNA damage in pediatric children with autism spectrum disorder [Texte imprimé et/ou numérique] / Eman Ahmed ZAKY, Auteur ; Salwa Amin Abd ELHAMEED, Auteur ; Shimaa Mostafa ISMAIL, Auteur ; Nourhan Moustafa ELDAMER, Auteur ; Asmaa Wafeeq ABDELAZIZ, Auteur . - p.102129. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 102 (April 2023) . - p.102129 Mots-clés : Autism spectrum disorder  Oxidative stress  Oxidative DNA damage  8-hydroxy-2?-deoxyguanosine Index. décimale : PER Périodiques Résumé : Background Autism spectrum disorder (ASD) is a neurodevelopmental condition that manifests itself in infancy. While genetic factors are the most important in its development, numerous other variables, as neurological, environmental, and immunological factors, have been found. The imbalance of oxidants and antioxidants has a role in the pathogenesis of ASD. We evaluated children with autism for the presence of oxidative DNA damage (ODD) biomarker 8-hydroxy-2-deoxyguanosine (8OHdG) and assessed its association with disease severity, and omega 3 supplementation. Methods A total of 102 children (51 children with ASD and 51 typically developed children) were recruited for this observational controlled cross-sectional study. Childhood Autism Rating Scale (CARS) was used to measure the severity of autism. The urinary 8-OH-dG was determined by using the ELISA method. Results urinary 8-OH-dG/creatinine levels were significantly higher in children with autism compared to their healthy peers (P < 0.001) with positive significant association with disease duration, severity, and positive family history (P = 0.03, P < 0.001, P = 0.03 respectively). Using a cut-of value of > 1.7, urinary 8-OHdG/creatinine ratios showed sensitivity and specificity of 80.39% and 74.51% respectively as a good discriminating power between normal and autistic children. Additionally, statistically lower significant urinary 8-OHdG/creatinine was found among ASD children received omega 3 than those who didn?t receive it (p < 0.001). Conclusion Increased urinary 8-OHdG/creatinine levels indicate an important role of oxidative DNA damage in ASD, and its significant higher level in ASD children with severe social impairment may be used as a potential non-invasive biomarker for disease severity. En ligne : https://doi.org/10.1016/j.rasd.2023.102129 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=501

Caregivers' views on cannabis use for their children with autism / Taylor T. SIVORI in Research in Autism Spectrum Disorders, 102 (April 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 102 (April 2023) . - p.102130 Titre : Caregivers' views on cannabis use for their children with autism Type de document : Texte imprimé et/ou numérique Auteurs : Taylor T. SIVORI, Auteur ; Maclain CAPRON, Auteur ; Daniel GRAVES, Auteur ; Jill HARRIS, Auteur ; Roseann C. SCHAAF, Auteur Article en page(s) : p.102130 Langues : Anglais (eng) Mots-clés : Autism  ASD  Cannabis  Caregiver  Knowledge  Survey Index. décimale : PER Périodiques Résumé : Background Autism is a neurodevelopmental disorder impacting 1 in 44 children that is characterized by decreased social communication and problem behaviors. Despite the increasing accessibility of cannabis, there is limited guidance about its use and usefulness for autism. The purpose of this study is to query caregivers of autistic children about their experience, knowledge and interest in medical cannabis use for their children. Method Survey methodology was used to query caregivers of autistic children between ages five to ten years. Informants recruited through a large children?s hospital in New Jersey and the Autism Speaks website. Descriptive analyses of frequencies and percentages are reported and relationships among socio-demographic variables and survey responses were conducted. Results Of the 4385 surveys sent, 568 responded. Informants were primarily white or Latino, female, and without a college education. Most were not familiar with cannabis use in autism; 7.2 % had experience providing their child with cannabis. Information about cannabis was drawn mainly from the Internet. Eighty-five percent of participants reported that they were willing to try cannabis for their child with ASD to address difficulty focusing, hyperactivity, sensory sensitivities, and anxiety. About half of those respondents were concerned about interactions between cannabis and current medications. Conclusions Findings suggest a willingness among caregivers to use cannabis for their children with ASD, but a need for more informed guidance on this topic. More studies are needed to understand the utility of cannabis for autistic individuals; clear and reputable information about cannabis and ASD is needed. En ligne : https://doi.org/10.1016/j.rasd.2023.102130 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=501 [article] Caregivers' views on cannabis use for their children with autism [Texte imprimé et/ou numérique] / Taylor T. SIVORI, Auteur ; Maclain CAPRON, Auteur ; Daniel GRAVES, Auteur ; Jill HARRIS, Auteur ; Roseann C. SCHAAF, Auteur . - p.102130. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 102 (April 2023) . - p.102130 Mots-clés : Autism  ASD  Cannabis  Caregiver  Knowledge  Survey Index. décimale : PER Périodiques Résumé : Background Autism is a neurodevelopmental disorder impacting 1 in 44 children that is characterized by decreased social communication and problem behaviors. Despite the increasing accessibility of cannabis, there is limited guidance about its use and usefulness for autism. The purpose of this study is to query caregivers of autistic children about their experience, knowledge and interest in medical cannabis use for their children. Method Survey methodology was used to query caregivers of autistic children between ages five to ten years. Informants recruited through a large children?s hospital in New Jersey and the Autism Speaks website. Descriptive analyses of frequencies and percentages are reported and relationships among socio-demographic variables and survey responses were conducted. Results Of the 4385 surveys sent, 568 responded. Informants were primarily white or Latino, female, and without a college education. Most were not familiar with cannabis use in autism; 7.2 % had experience providing their child with cannabis. Information about cannabis was drawn mainly from the Internet. Eighty-five percent of participants reported that they were willing to try cannabis for their child with ASD to address difficulty focusing, hyperactivity, sensory sensitivities, and anxiety. About half of those respondents were concerned about interactions between cannabis and current medications. Conclusions Findings suggest a willingness among caregivers to use cannabis for their children with ASD, but a need for more informed guidance on this topic. More studies are needed to understand the utility of cannabis for autistic individuals; clear and reputable information about cannabis and ASD is needed. En ligne : https://doi.org/10.1016/j.rasd.2023.102130 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=501

Effectiveness of deep brain stimulation in refractory and drug-resistant aggressiveness in autism spectrum disorder / JuanCarlos BENEDETTI-ISAAC in Research in Autism Spectrum Disorders, 102 (April 2023)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 102 (April 2023) . - p.102131 Titre : Effectiveness of deep brain stimulation in refractory and drug-resistant aggressiveness in autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : JuanCarlos BENEDETTI-ISAAC, Auteur ; Loida CAMARGO, Auteur ; Fernando P. CARDENAS, Auteur ; Norman LÓPEZ, Auteur Article en page(s) : p.102131 Langues : Anglais (eng) Mots-clés : DBS  Severe  ASD  Refractory aggressiveness Index. décimale : PER Périodiques Résumé : Background Aggressive behavior, resistant to pharmacological and psychological treatment, is observed in some cases of autism. The main objective of this study is to analyze the efficacy of deep brain stimulation (DBS) for aggressive behavior in severe autism Method The effectiveness of DBS was analyzed in a clinical follow-up of 5 autistic patients, with impaired functional activity and refractoriness to psychopharmacological and behavioral treatment. The patients were examined in medical meetings and evaluated by experienced professionals using the Overt Aggressiveness Scale (OAS), before surgical implantation and after 6, 12 and, 18 months of follow-up. Student's t-test analyses were performed to assess changes in aggressiveness scores. The effect size of surgical intervention on patients' OAS performance was estimated Results Before the intervention, patients scored very high on the aggressiveness scale. In the subsequent medical controls, a clinically and psychometrically significant decrease in aggressiveness and self-injury symptoms was observed. These data were confirmed by the parents up to 18 months of follow-up. Very large effect sizes were obtained in favor of DBS Conclusions In this case series, DBS significantly reduced aggressiveness and self-injury, favoring functionality, social adaptation of the patients, and improving the quality of life of the family. We believe that DBS may be a viable treatment option. En ligne : https://doi.org/10.1016/j.rasd.2023.102131 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=501 [article] Effectiveness of deep brain stimulation in refractory and drug-resistant aggressiveness in autism spectrum disorder [Texte imprimé et/ou numérique] / JuanCarlos BENEDETTI-ISAAC, Auteur ; Loida CAMARGO, Auteur ; Fernando P. CARDENAS, Auteur ; Norman LÓPEZ, Auteur . - p.102131. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 102 (April 2023) . - p.102131 Mots-clés : DBS  Severe  ASD  Refractory aggressiveness Index. décimale : PER Périodiques Résumé : Background Aggressive behavior, resistant to pharmacological and psychological treatment, is observed in some cases of autism. The main objective of this study is to analyze the efficacy of deep brain stimulation (DBS) for aggressive behavior in severe autism Method The effectiveness of DBS was analyzed in a clinical follow-up of 5 autistic patients, with impaired functional activity and refractoriness to psychopharmacological and behavioral treatment. The patients were examined in medical meetings and evaluated by experienced professionals using the Overt Aggressiveness Scale (OAS), before surgical implantation and after 6, 12 and, 18 months of follow-up. Student's t-test analyses were performed to assess changes in aggressiveness scores. The effect size of surgical intervention on patients' OAS performance was estimated Results Before the intervention, patients scored very high on the aggressiveness scale. In the subsequent medical controls, a clinically and psychometrically significant decrease in aggressiveness and self-injury symptoms was observed. These data were confirmed by the parents up to 18 months of follow-up. Very large effect sizes were obtained in favor of DBS Conclusions In this case series, DBS significantly reduced aggressiveness and self-injury, favoring functionality, social adaptation of the patients, and improving the quality of life of the family. We believe that DBS may be a viable treatment option. En ligne : https://doi.org/10.1016/j.rasd.2023.102131 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=501