Assessment of olfactory detection thresholds in children with autism spectrum disorders using a pulse ejection system / Hirokazu KUMAZAKI in Molecular Autism, 7 (2016)  

Public ISBD [article]  inMolecular Autism > 7 (2016) . - 6p. Titre : Assessment of olfactory detection thresholds in children with autism spectrum disorders using a pulse ejection system Type de document : texte imprimé Auteurs : Hirokazu KUMAZAKI, Auteur ; Taro MURAMATSU, Auteur ; Takashi X. FUJISAWA, Auteur ; Masutomo MIYAO, Auteur ; Eri MATSUURA, Auteur ; Ken-ichi OKADA, Auteur ; Hirotaka KOSAKA, Auteur ; Akemi TOMODA, Auteur ; Masaru MIMURA, Auteur Article en page(s) : 6p. Langues : Anglais (eng) Mots-clés : Adolescent  Aerosols  Autism Spectrum Disorder/physiopathology/psychology  Caproates  Case-Control Studies  Child  Diagnostic Equipment  Equipment Design  Female  Humans  Hypesthesia/etiology/physiopathology/psychology  Male  Odorants  Olfactory Perception/physiology  Pentanols  Pulsatile Flow  Sensory Thresholds/physiology  Autism spectrum disorder  Laboratory-based studies  Olfaction  Olfactory detection threshold  Pulse ejection system Index. décimale : PER Périodiques Résumé : BACKGROUND: Atypical responsiveness to olfactory stimuli has been reported as the strongest predictor of social impairment in children with autism spectrum disorders (ASD). However, previous laboratory-based sensory psychophysical studies that have aimed to investigate olfactory sensitivity in children with ASD have produced inconsistent results. The methodology of these studies is limited by several factors, and more sophisticated approaches are required to produce consistent results. METHODS: We measured olfactory detection thresholds in children with ASD and typical development (TD) using a pulse ejection system-a newly developed methodology designed to resolve problems encountered in previous studies. The two odorants used as stimuli were isoamyl acetate and allyl caproate. RESULTS: Forty-three participants took part in this study: 23 (6 females, 17 males) children with ASD and 20 with TD (6 females, 14 males). Olfactory detection thresholds of children with ASD were significantly higher than those of TD children with both isoamyl acetate (2.85 +/- 0.28 vs 1.57 +/- 0.15; p < 0.001) and allyl caproate ( 3.30 +/- 0.23 vs 1.17 +/- 0.08; p < 0.001). CONCLUSIONS: We found impaired olfactory detection thresholds in children with ASD. Our results contribute to a better understanding of the olfactory abnormalities that children with ASD experience. Considering the role and effect that odors play in our daily lives, insensitivity to some odorants might have a tremendous impact on children with ASD. Future studies of olfactory processing in ASD may reveal important links between brain function, clinically relevant behavior, and treatment. En ligne : http://dx.doi.org/10.1186/s13229-016-0071-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=328 [article] Assessment of olfactory detection thresholds in children with autism spectrum disorders using a pulse ejection system [texte imprimé] / Hirokazu KUMAZAKI, Auteur ; Taro MURAMATSU, Auteur ; Takashi X. FUJISAWA, Auteur ; Masutomo MIYAO, Auteur ; Eri MATSUURA, Auteur ; Ken-ichi OKADA, Auteur ; Hirotaka KOSAKA, Auteur ; Akemi TOMODA, Auteur ; Masaru MIMURA, Auteur . - 6p. Langues : Anglais (eng) in Molecular Autism > 7 (2016) . - 6p. Mots-clés : Adolescent  Aerosols  Autism Spectrum Disorder/physiopathology/psychology  Caproates  Case-Control Studies  Child  Diagnostic Equipment  Equipment Design  Female  Humans  Hypesthesia/etiology/physiopathology/psychology  Male  Odorants  Olfactory Perception/physiology  Pentanols  Pulsatile Flow  Sensory Thresholds/physiology  Autism spectrum disorder  Laboratory-based studies  Olfaction  Olfactory detection threshold  Pulse ejection system Index. décimale : PER Périodiques Résumé : BACKGROUND: Atypical responsiveness to olfactory stimuli has been reported as the strongest predictor of social impairment in children with autism spectrum disorders (ASD). However, previous laboratory-based sensory psychophysical studies that have aimed to investigate olfactory sensitivity in children with ASD have produced inconsistent results. The methodology of these studies is limited by several factors, and more sophisticated approaches are required to produce consistent results. METHODS: We measured olfactory detection thresholds in children with ASD and typical development (TD) using a pulse ejection system-a newly developed methodology designed to resolve problems encountered in previous studies. The two odorants used as stimuli were isoamyl acetate and allyl caproate. RESULTS: Forty-three participants took part in this study: 23 (6 females, 17 males) children with ASD and 20 with TD (6 females, 14 males). Olfactory detection thresholds of children with ASD were significantly higher than those of TD children with both isoamyl acetate (2.85 +/- 0.28 vs 1.57 +/- 0.15; p < 0.001) and allyl caproate ( 3.30 +/- 0.23 vs 1.17 +/- 0.08; p < 0.001). CONCLUSIONS: We found impaired olfactory detection thresholds in children with ASD. Our results contribute to a better understanding of the olfactory abnormalities that children with ASD experience. Considering the role and effect that odors play in our daily lives, insensitivity to some odorants might have a tremendous impact on children with ASD. Future studies of olfactory processing in ASD may reveal important links between brain function, clinically relevant behavior, and treatment. En ligne : http://dx.doi.org/10.1186/s13229-016-0071-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=328

Brief Report: A Novel System to Evaluate Autism Spectrum Disorders Using Two Humanoid Robots / Hirokazu KUMAZAKI in Journal of Autism and Developmental Disorders, 49-4 (April 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-4 (April 2019) . - p.1709-1716 Titre : Brief Report: A Novel System to Evaluate Autism Spectrum Disorders Using Two Humanoid Robots Type de document : texte imprimé Auteurs : Hirokazu KUMAZAKI, Auteur ; Taro MURAMATSU, Auteur ; Yuichiro YOSHIKAWA, Auteur ; Yuko YOSHIMURA, Auteur ; Takashi IKEDA, Auteur ; Chiaki HASEGAWA, Auteur ; Daisuke N. SAITO, Auteur ; Jiro SHIMAYA, Auteur ; Hiroshi ISHIGURO, Auteur ; Masaru MIMURA, Auteur ; Mitsuru KIKUCHI, Auteur Article en page(s) : p.1709-1716 Langues : Anglais (eng) Mots-clés : Ados  Autism spectrum disorders  Robot  Severity  Social communication  Typical development Index. décimale : PER Périodiques Résumé : We investigated the feasibility of our novel evaluation system for use with children with autism spectrum disorders (ASD). We prepared the experimental setting with two humanoid robots in reference to the birthday party scene in the Autism Diagnostic Observational Schedule (ADOS). We assessed the relationship between social communication ability measured in the ADOS condition (i.e., with a human clinician) and in a robotic condition for children with ASD. There were significant correlations between the social communication scores in the gold-standard ADOS condition and the robotic condition for children with ASD. The current work provides support for a unique application of a robotic system (i.e., two robot-mediated interaction) to evaluate the severity of autistic traits for children with ASD. En ligne : https://dx.doi.org/10.1007/s10803-018-3848-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=388 [article] Brief Report: A Novel System to Evaluate Autism Spectrum Disorders Using Two Humanoid Robots [texte imprimé] / Hirokazu KUMAZAKI, Auteur ; Taro MURAMATSU, Auteur ; Yuichiro YOSHIKAWA, Auteur ; Yuko YOSHIMURA, Auteur ; Takashi IKEDA, Auteur ; Chiaki HASEGAWA, Auteur ; Daisuke N. SAITO, Auteur ; Jiro SHIMAYA, Auteur ; Hiroshi ISHIGURO, Auteur ; Masaru MIMURA, Auteur ; Mitsuru KIKUCHI, Auteur . - p.1709-1716. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-4 (April 2019) . - p.1709-1716 Mots-clés : Ados  Autism spectrum disorders  Robot  Severity  Social communication  Typical development Index. décimale : PER Périodiques Résumé : We investigated the feasibility of our novel evaluation system for use with children with autism spectrum disorders (ASD). We prepared the experimental setting with two humanoid robots in reference to the birthday party scene in the Autism Diagnostic Observational Schedule (ADOS). We assessed the relationship between social communication ability measured in the ADOS condition (i.e., with a human clinician) and in a robotic condition for children with ASD. There were significant correlations between the social communication scores in the gold-standard ADOS condition and the robotic condition for children with ASD. The current work provides support for a unique application of a robotic system (i.e., two robot-mediated interaction) to evaluate the severity of autistic traits for children with ASD. En ligne : https://dx.doi.org/10.1007/s10803-018-3848-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=388

Brief Report: Olfactory Adaptation in Children with Autism Spectrum Disorders / Hirokazu KUMAZAKI in Journal of Autism and Developmental Disorders, 49-8 (August 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-8 (August 2019) . - p.3462-3469 Titre : Brief Report: Olfactory Adaptation in Children with Autism Spectrum Disorders Type de document : texte imprimé Auteurs : Hirokazu KUMAZAKI, Auteur ; Taro MURAMATSU, Auteur ; Masutomo MIYAO, Auteur ; Ken-ichi OKADA, Auteur ; Masaru MIMURA, Auteur ; Mitsuru KIKUCHI, Auteur Article en page(s) : p.3462-3469 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Olfactory adaptation  Pulse ejection system  Social impairment  Typical development Index. décimale : PER Périodiques Résumé : Olfactory adaptation is an important process that allows the individual to adjust to changes in the environment. This process has been proposed to be aberrant in individuals with autism spectrum disorders (ASD). However, few studies have examined olfactory adaptation in children with ASD. We examined olfactory adaptation in children with ASD and typically developing (TD) children using a pulse ejection system, which resolved problems associated with previous laboratory-based olfactory psychophysical studies. Nine children with ASD and nine TD children participated in this study and all participants completed the entire experiment. Using this system, we found that the TD group showed greater adaptation than the ASD group. Our results provide a better understanding of olfactory adaptation in children with ASD. En ligne : http://dx.doi.org/10.1007/s10803-019-04053-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=403 [article] Brief Report: Olfactory Adaptation in Children with Autism Spectrum Disorders [texte imprimé] / Hirokazu KUMAZAKI, Auteur ; Taro MURAMATSU, Auteur ; Masutomo MIYAO, Auteur ; Ken-ichi OKADA, Auteur ; Masaru MIMURA, Auteur ; Mitsuru KIKUCHI, Auteur . - p.3462-3469. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-8 (August 2019) . - p.3462-3469 Mots-clés : Autism spectrum disorders  Olfactory adaptation  Pulse ejection system  Social impairment  Typical development Index. décimale : PER Périodiques Résumé : Olfactory adaptation is an important process that allows the individual to adjust to changes in the environment. This process has been proposed to be aberrant in individuals with autism spectrum disorders (ASD). However, few studies have examined olfactory adaptation in children with ASD. We examined olfactory adaptation in children with ASD and typically developing (TD) children using a pulse ejection system, which resolved problems associated with previous laboratory-based olfactory psychophysical studies. Nine children with ASD and nine TD children participated in this study and all participants completed the entire experiment. Using this system, we found that the TD group showed greater adaptation than the ASD group. Our results provide a better understanding of olfactory adaptation in children with ASD. En ligne : http://dx.doi.org/10.1007/s10803-019-04053-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=403

Brief Report: The Effectiveness of Hugging a Huggable Device Before Having a Conversation with an Unfamiliar Person for Autism Spectrum Disorders / Hirokazu KUMAZAKI in Journal of Autism and Developmental Disorders, 52-7 (July 2022)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 52-7 (July 2022) . - p.3294-3303 Titre : Brief Report: The Effectiveness of Hugging a Huggable Device Before Having a Conversation with an Unfamiliar Person for Autism Spectrum Disorders Type de document : texte imprimé Auteurs : Hirokazu KUMAZAKI, Auteur ; Hidenobu SUMIOKA, Auteur ; Taro MURAMATSU, Auteur ; Yuichiro YOSHIKAWA, Auteur ; Jiro SHIMAYA, Auteur ; Ryoichiro IWANAGA, Auteur ; Hiroshi ISHIGURO, Auteur ; Tomiki SUMIYOSHI, Auteur ; Masaru MIMURA, Auteur Article en page(s) : p.3294-3303 Langues : Anglais (eng) Mots-clés : Anxiety/psychology/therapy  Autism Spectrum Disorder/complications/therapy  Humans  Stress, Psychological  Touch  Autism spectrum disorders  Robot  Sensory over-responsivity  Sensory seeking  Social anxiety  Tactile Index. décimale : PER Périodiques Résumé : Sensory overresponsivity (SOR) emerges before anxiety and positively predicts subsequent increasing levels of anxiety in individuals with autism spectrum disorder (ASD). Sensory seeking behavior occurs as compensation for SOR, and individuals may seek sensory input in one sensory domain to compensate for SOR. Tactile seeking behavior is sufficient to decrease social anxiety in communicating with unfamiliar people. We assessed the effectiveness of hugging a huggable device before a conversation for reducing the psychological stress associated with speaking to an unfamiliar person or robot. Our analysis showed a significant effect, with Hugvie contributing to decreased stress for both interlocutors. Thus, this study demonstrated the efficacy of hugging it before conversation, which emphasizes the importance of tactile seeking for individuals with ASD. En ligne : http://dx.doi.org/10.1007/s10803-021-05173-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=477 [article] Brief Report: The Effectiveness of Hugging a Huggable Device Before Having a Conversation with an Unfamiliar Person for Autism Spectrum Disorders [texte imprimé] / Hirokazu KUMAZAKI, Auteur ; Hidenobu SUMIOKA, Auteur ; Taro MURAMATSU, Auteur ; Yuichiro YOSHIKAWA, Auteur ; Jiro SHIMAYA, Auteur ; Ryoichiro IWANAGA, Auteur ; Hiroshi ISHIGURO, Auteur ; Tomiki SUMIYOSHI, Auteur ; Masaru MIMURA, Auteur . - p.3294-3303. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 52-7 (July 2022) . - p.3294-3303 Mots-clés : Anxiety/psychology/therapy  Autism Spectrum Disorder/complications/therapy  Humans  Stress, Psychological  Touch  Autism spectrum disorders  Robot  Sensory over-responsivity  Sensory seeking  Social anxiety  Tactile Index. décimale : PER Périodiques Résumé : Sensory overresponsivity (SOR) emerges before anxiety and positively predicts subsequent increasing levels of anxiety in individuals with autism spectrum disorder (ASD). Sensory seeking behavior occurs as compensation for SOR, and individuals may seek sensory input in one sensory domain to compensate for SOR. Tactile seeking behavior is sufficient to decrease social anxiety in communicating with unfamiliar people. We assessed the effectiveness of hugging a huggable device before a conversation for reducing the psychological stress associated with speaking to an unfamiliar person or robot. Our analysis showed a significant effect, with Hugvie contributing to decreased stress for both interlocutors. Thus, this study demonstrated the efficacy of hugging it before conversation, which emphasizes the importance of tactile seeking for individuals with ASD. En ligne : http://dx.doi.org/10.1007/s10803-021-05173-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=477

Job interview training targeting nonverbal communication using an android robot for individuals with autism spectrum disorder / Hirokazu KUMAZAKI in Autism, 23-6 (August 2019)  

Public ISBD [article]  inAutism > 23-6 (August 2019) . - p.1586-1595 Titre : Job interview training targeting nonverbal communication using an android robot for individuals with autism spectrum disorder Type de document : texte imprimé Auteurs : Hirokazu KUMAZAKI, Auteur ; Taro MURAMATSU, Auteur ; Yuichiro YOSHIKAWA, Auteur ; Blythe A. CORBETT, Auteur ; Yuki MATSUMOTO, Auteur ; Haruhiro HIGASHIDA, Auteur ; Teruko YUHI, Auteur ; Hiroshi ISHIGURO, Auteur ; Masaru MIMURA, Auteur ; Mitsuru KIKUCHI, Auteur Article en page(s) : p.1586-1595 Langues : Anglais (eng) Mots-clés : android robot  autism spectrum disorder  cortisol  job interview  nonverbal communication Index. décimale : PER Périodiques Résumé : Job interviews are significant barriers for individuals with autism spectrum disorder because these individuals lack good nonverbal communication skills. We developed a job interview training program using an android robot. The job interview training program using an android robot consists the following three stages: (1) tele-operating an android robot and conversing with others through the android robot, (2) a face-to-face mock job interview with the android robot, and (3) feedback based on the mock job interview and nonverbal communication exercises using the android robot. The participants were randomly assigned to the following two groups: one group received a combined intervention with "interview guidance by teachers and job interview training program using an android robot" (n = 13), and the other group received an intervention with interview guidance by teachers alone (n = 16). Before and after the intervention, the participants in both groups underwent a mock job interview with a human interviewer, who provided outcome measurements of nonverbal communication, self-confidence, and salivary cortisol. After the training sessions, the participants who received the combined interview guidance by teachers and the job interview training program using an android robot intervention displayed improved nonverbal communication skills and self-confidence and had significantly lower levels of salivary cortisol than the participants who only received interview guidance by teachers. The job interview training program using an android robot improved various measures of job interview skills in individuals with autism spectrum disorder. En ligne : http://dx.doi.org/10.1177/1362361319827134 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=403 [article] Job interview training targeting nonverbal communication using an android robot for individuals with autism spectrum disorder [texte imprimé] / Hirokazu KUMAZAKI, Auteur ; Taro MURAMATSU, Auteur ; Yuichiro YOSHIKAWA, Auteur ; Blythe A. CORBETT, Auteur ; Yuki MATSUMOTO, Auteur ; Haruhiro HIGASHIDA, Auteur ; Teruko YUHI, Auteur ; Hiroshi ISHIGURO, Auteur ; Masaru MIMURA, Auteur ; Mitsuru KIKUCHI, Auteur . - p.1586-1595. Langues : Anglais (eng) in Autism > 23-6 (August 2019) . - p.1586-1595 Mots-clés : android robot  autism spectrum disorder  cortisol  job interview  nonverbal communication Index. décimale : PER Périodiques Résumé : Job interviews are significant barriers for individuals with autism spectrum disorder because these individuals lack good nonverbal communication skills. We developed a job interview training program using an android robot. The job interview training program using an android robot consists the following three stages: (1) tele-operating an android robot and conversing with others through the android robot, (2) a face-to-face mock job interview with the android robot, and (3) feedback based on the mock job interview and nonverbal communication exercises using the android robot. The participants were randomly assigned to the following two groups: one group received a combined intervention with "interview guidance by teachers and job interview training program using an android robot" (n = 13), and the other group received an intervention with interview guidance by teachers alone (n = 16). Before and after the intervention, the participants in both groups underwent a mock job interview with a human interviewer, who provided outcome measurements of nonverbal communication, self-confidence, and salivary cortisol. After the training sessions, the participants who received the combined interview guidance by teachers and the job interview training program using an android robot intervention displayed improved nonverbal communication skills and self-confidence and had significantly lower levels of salivary cortisol than the participants who only received interview guidance by teachers. The job interview training program using an android robot improved various measures of job interview skills in individuals with autism spectrum disorder. En ligne : http://dx.doi.org/10.1177/1362361319827134 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=403

Sex differences in cognitive and symptom profiles in children with high functioning autism spectrum disorders / Hirokazu KUMAZAKI in Research in Autism Spectrum Disorders, 13-14 (May 2015)  

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