14 recherche sur le mot-clé 'Autism Spectrum Disorder/physiopathology/psychology'

Emotional decision-making in autism spectrum disorder: the roles of interoception and alexithymia / P. SHAH in Molecular Autism, 7 (2016)  

Public ISBD [article]  inMolecular Autism > 7 (2016) . - 43p. Titre : Emotional decision-making in autism spectrum disorder: the roles of interoception and alexithymia Type de document : Texte imprimé et/ou numérique Auteurs : P. SHAH, Auteur ; Caroline CATMUR, Auteur ; Geoffrey BIRD, Auteur Article en page(s) : 43p. Langues : Anglais (eng) Mots-clés : Adult  Affective Symptoms/physiopathology/psychology  Autism Spectrum Disorder/physiopathology/psychology  Case-Control Studies  Decision Making  Female  Frustration  Happiness  Humans  Intelligence Tests  Interoception/physiology  Male  Alexithymia  Autism  Decision-making  Emotion  Framing effect  Insula  Interoception  Replication Index. décimale : PER Périodiques Résumé : The way choices are framed influences decision-making. These "framing effects" emerge through the integration of emotional responses into decision-making under uncertainty. It was previously reported that susceptibility to the framing effect was reduced in individuals with autism spectrum disorder (ASD) due to a reduced tendency to incorporate emotional information into the decision-making process. However, recent research indicates that, where observed, emotional processing impairments in ASD may be due to co-occurring alexithymia. Alexithymia is thought to arise due to impaired interoception (the ability to perceive the internal state of one's body), raising the possibility that emotional signals are not perceived and thus not integrated into decision-making in those with alexithymia and that therefore reduced framing effects in ASD are a product of co-occurring alexithymia rather than ASD per se. Accordingly, the present study compared framing effects in autistic individuals with neurotypical controls matched for alexithymia. Results showed a marked deviation between groups. The framing effect was, in line with previous data, significantly smaller in autistic individuals, and there was no relationship between alexithymia or interoception and decision-making in the ASD group. In the neurotypical group, however, the size of the framing effect was associated with alexithymia and interoception, even after controlling for autistic traits. These results demonstrate that although framing effects are associated with interoception and alexithymia in the neurotypical population, emotional and interoceptive signals have less impact upon the decision-making process in ASD. En ligne : http://dx.doi.org/10.1186/s13229-016-0104-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=329 [article] Emotional decision-making in autism spectrum disorder: the roles of interoception and alexithymia [Texte imprimé et/ou numérique] / P. SHAH, Auteur ; Caroline CATMUR, Auteur ; Geoffrey BIRD, Auteur . - 43p. Langues : Anglais (eng) in Molecular Autism > 7 (2016) . - 43p. Mots-clés : Adult  Affective Symptoms/physiopathology/psychology  Autism Spectrum Disorder/physiopathology/psychology  Case-Control Studies  Decision Making  Female  Frustration  Happiness  Humans  Intelligence Tests  Interoception/physiology  Male  Alexithymia  Autism  Decision-making  Emotion  Framing effect  Insula  Interoception  Replication Index. décimale : PER Périodiques Résumé : The way choices are framed influences decision-making. These "framing effects" emerge through the integration of emotional responses into decision-making under uncertainty. It was previously reported that susceptibility to the framing effect was reduced in individuals with autism spectrum disorder (ASD) due to a reduced tendency to incorporate emotional information into the decision-making process. However, recent research indicates that, where observed, emotional processing impairments in ASD may be due to co-occurring alexithymia. Alexithymia is thought to arise due to impaired interoception (the ability to perceive the internal state of one's body), raising the possibility that emotional signals are not perceived and thus not integrated into decision-making in those with alexithymia and that therefore reduced framing effects in ASD are a product of co-occurring alexithymia rather than ASD per se. Accordingly, the present study compared framing effects in autistic individuals with neurotypical controls matched for alexithymia. Results showed a marked deviation between groups. The framing effect was, in line with previous data, significantly smaller in autistic individuals, and there was no relationship between alexithymia or interoception and decision-making in the ASD group. In the neurotypical group, however, the size of the framing effect was associated with alexithymia and interoception, even after controlling for autistic traits. These results demonstrate that although framing effects are associated with interoception and alexithymia in the neurotypical population, emotional and interoceptive signals have less impact upon the decision-making process in ASD. En ligne : http://dx.doi.org/10.1186/s13229-016-0104-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=329

Executive Functioning: A Mediator Between Sensory Processing and Behaviour in Autism Spectrum Disorder / M. FERNANDEZ-PRIETO in Journal of Autism and Developmental Disorders, 51-6 (June 2021)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 51-6 (June 2021) . - p.2091-2103 Titre : Executive Functioning: A Mediator Between Sensory Processing and Behaviour in Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : M. FERNANDEZ-PRIETO, Auteur ; C. MOREIRA, Auteur ; S. CRUZ, Auteur ; V. CAMPOS, Auteur ; R. MARTÍNEZ-REGUEIRO, Auteur ; M. TABOADA, Auteur ; A. CARRACEDO, Auteur ; A. SAMPAIO, Auteur Article en page(s) : p.2091-2103 Langues : Anglais (eng) Mots-clés : Adolescent  Autism Spectrum Disorder/physiopathology/psychology  Behavior Rating Scale  Child  Child Behavior/psychology  Child, Preschool  Executive Function/physiology  Female  Humans  Male  Sensation/physiology  Surveys and Questionnaires  Asd  Behaviour  Emotion regulation and control  Executive functions  Sensory processing Index. décimale : PER Périodiques Résumé : Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social interaction, executive functioning, sensory-perceptual abilities and behaviour, such as anxious/depressed states, attention problems, aggression, or somatic complains. However, the dynamic relationship between these dimensions remains to be addressed. Therefore, we explored the link between executive functions, sensory processing and behaviour in 79 children and adolescents with ASD. Results showed significant associations between all dimensions-executive functions, sensory processing and behaviour. Furthermore, using structural equation modelling methods, we observed a mediation effect of executive functioning, specifically the domain pertaining to emotion regulation and control, and in the relationship between sensory processing abnormalities and behavioural problems. We discuss the importance of emotion regulation as a mediator between sensory processing and behavioural impairments and its impact in social competence in ASD. En ligne : http://dx.doi.org/10.1007/s10803-020-04648-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452 [article] Executive Functioning: A Mediator Between Sensory Processing and Behaviour in Autism Spectrum Disorder [Texte imprimé et/ou numérique] / M. FERNANDEZ-PRIETO, Auteur ; C. MOREIRA, Auteur ; S. CRUZ, Auteur ; V. CAMPOS, Auteur ; R. MARTÍNEZ-REGUEIRO, Auteur ; M. TABOADA, Auteur ; A. CARRACEDO, Auteur ; A. SAMPAIO, Auteur . - p.2091-2103. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 51-6 (June 2021) . - p.2091-2103 Mots-clés : Adolescent  Autism Spectrum Disorder/physiopathology/psychology  Behavior Rating Scale  Child  Child Behavior/psychology  Child, Preschool  Executive Function/physiology  Female  Humans  Male  Sensation/physiology  Surveys and Questionnaires  Asd  Behaviour  Emotion regulation and control  Executive functions  Sensory processing Index. décimale : PER Périodiques Résumé : Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social interaction, executive functioning, sensory-perceptual abilities and behaviour, such as anxious/depressed states, attention problems, aggression, or somatic complains. However, the dynamic relationship between these dimensions remains to be addressed. Therefore, we explored the link between executive functions, sensory processing and behaviour in 79 children and adolescents with ASD. Results showed significant associations between all dimensions-executive functions, sensory processing and behaviour. Furthermore, using structural equation modelling methods, we observed a mediation effect of executive functioning, specifically the domain pertaining to emotion regulation and control, and in the relationship between sensory processing abnormalities and behavioural problems. We discuss the importance of emotion regulation as a mediator between sensory processing and behavioural impairments and its impact in social competence in ASD. En ligne : http://dx.doi.org/10.1007/s10803-020-04648-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452

Implicit Semantic Processing of Linguistic and Non-linguistic Stimuli in Adults with Autism Spectrum Disorder / E. O'ROURKE in Journal of Autism and Developmental Disorders, 51-8 (August 2021)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 51-8 (August 2021) . - p.2611-2630 Titre : Implicit Semantic Processing of Linguistic and Non-linguistic Stimuli in Adults with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : E. O'ROURKE, Auteur ; E. L. CODERRE, Auteur Article en page(s) : p.2611-2630 Langues : Anglais (eng) Mots-clés : Acoustic Stimulation/psychology  Adolescent  Adult  Autism Spectrum Disorder/physiopathology/psychology  Autistic Disorder  Electroencephalography  Evoked Potentials/physiology  Humans  Language  Male  Semantics  Autism  Event-related potentials  N400  Semantic integration Index. décimale : PER Périodiques Résumé : While many individuals with autism spectrum disorder (ASD) experience difficulties with language processing, non-linguistic semantic processing may be intact. We examined neural responses to an implicit semantic priming task by comparing N400 responses-an event-related potential related to semantic processing-in response to semantically related or unrelated pairs of words or pictures. Adults with ASD showed larger N400 responses than typically developing adults for pictures, but no group differences occurred for words. However, we also observed complex modulations of N400 amplitude by age and by level of autistic traits. These results offer important implications for how groups are delineated and compared in autism research. En ligne : http://dx.doi.org/10.1007/s10803-020-04736-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452 [article] Implicit Semantic Processing of Linguistic and Non-linguistic Stimuli in Adults with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / E. O'ROURKE, Auteur ; E. L. CODERRE, Auteur . - p.2611-2630. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 51-8 (August 2021) . - p.2611-2630 Mots-clés : Acoustic Stimulation/psychology  Adolescent  Adult  Autism Spectrum Disorder/physiopathology/psychology  Autistic Disorder  Electroencephalography  Evoked Potentials/physiology  Humans  Language  Male  Semantics  Autism  Event-related potentials  N400  Semantic integration Index. décimale : PER Périodiques Résumé : While many individuals with autism spectrum disorder (ASD) experience difficulties with language processing, non-linguistic semantic processing may be intact. We examined neural responses to an implicit semantic priming task by comparing N400 responses-an event-related potential related to semantic processing-in response to semantically related or unrelated pairs of words or pictures. Adults with ASD showed larger N400 responses than typically developing adults for pictures, but no group differences occurred for words. However, we also observed complex modulations of N400 amplitude by age and by level of autistic traits. These results offer important implications for how groups are delineated and compared in autism research. En ligne : http://dx.doi.org/10.1007/s10803-020-04736-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452

Mimetic desire in autism spectrum disorder / Baudouin FORGEOT D'ARC in Molecular Autism, 7 (2016)  

Public ISBD [article]  inMolecular Autism > 7 (2016) . - 45p. Titre : Mimetic desire in autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Baudouin FORGEOT D'ARC, Auteur ; F. VINCKIER, Auteur ; M. LEBRETON, Auteur ; I. SOULIERES, Auteur ; Laurent MOTTRON, Auteur ; M. PESSIGLIONE, Auteur Article en page(s) : 45p. Langues : Anglais (eng) Mots-clés : Adolescent  Adult  Anhedonia  Autism Spectrum Disorder/physiopathology/psychology  Case-Control Studies  Female  Humans  Imitative Behavior/physiology  Judgment  Male  Motivation/physiology  Psychological Tests  Social Perception  Autism  Brain valuation system  Mimetic desire  Mirror neuron system  Restricted interests  Social cognition  Social influence  Social motivation Index. décimale : PER Périodiques Résumé : Mimetic desire (MD), the spontaneous propensity to pursue goals that others pursue, is a case of social influence that is believed to shape preferences. Autism spectrum disorder (ASD) is defined by both atypical interests and altered social interaction. We investigated whether MD is lower in adults with ASD compared to typically developed adults and whether MD correlates with social anhedonia and social judgment, two aspects of atypical social functioning in autism. Contrary to our hypotheses, MD was similarly present in both ASD and control groups. Anhedonia and social judgment differed between the ASD and control groups but did not correlate with MD. These results extend previous findings by suggesting that basic mechanisms of social influence are preserved in autism. The finding of intact MD in ASD stands against the intuitive idea that atypical interests stem from reduced social influence and indirectly favors the possibility that special interests might be selected for their intrinsic properties. En ligne : http://dx.doi.org/10.1186/s13229-016-0107-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=328 [article] Mimetic desire in autism spectrum disorder [Texte imprimé et/ou numérique] / Baudouin FORGEOT D'ARC, Auteur ; F. VINCKIER, Auteur ; M. LEBRETON, Auteur ; I. SOULIERES, Auteur ; Laurent MOTTRON, Auteur ; M. PESSIGLIONE, Auteur . - 45p. Langues : Anglais (eng) in Molecular Autism > 7 (2016) . - 45p. Mots-clés : Adolescent  Adult  Anhedonia  Autism Spectrum Disorder/physiopathology/psychology  Case-Control Studies  Female  Humans  Imitative Behavior/physiology  Judgment  Male  Motivation/physiology  Psychological Tests  Social Perception  Autism  Brain valuation system  Mimetic desire  Mirror neuron system  Restricted interests  Social cognition  Social influence  Social motivation Index. décimale : PER Périodiques Résumé : Mimetic desire (MD), the spontaneous propensity to pursue goals that others pursue, is a case of social influence that is believed to shape preferences. Autism spectrum disorder (ASD) is defined by both atypical interests and altered social interaction. We investigated whether MD is lower in adults with ASD compared to typically developed adults and whether MD correlates with social anhedonia and social judgment, two aspects of atypical social functioning in autism. Contrary to our hypotheses, MD was similarly present in both ASD and control groups. Anhedonia and social judgment differed between the ASD and control groups but did not correlate with MD. These results extend previous findings by suggesting that basic mechanisms of social influence are preserved in autism. The finding of intact MD in ASD stands against the intuitive idea that atypical interests stem from reduced social influence and indirectly favors the possibility that special interests might be selected for their intrinsic properties. En ligne : http://dx.doi.org/10.1186/s13229-016-0107-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=328

The relationship between gamma-band neural oscillations and language skills in youth with Autism Spectrum Disorder and their first-degree relatives / Vardan ARUTIUNIAN in Molecular Autism, 15 (2024)  

Public ISBD [article]  inMolecular Autism > 15 (2024) . - 19p. Titre : The relationship between gamma-band neural oscillations and language skills in youth with Autism Spectrum Disorder and their first-degree relatives Type de document : Texte imprimé et/ou numérique Auteurs : Vardan ARUTIUNIAN, Auteur ; Megha SANTHOSH, Auteur ; Emily NEUHAUS, Auteur ; Heather BORLAND, Auteur ; Chris TOMPKINS, Auteur ; Raphael A. BERNIER, Auteur ; Susan Y. BOOKHEIMER, Auteur ; Mirella DAPRETTO, Auteur ; Abha R. GUPTA, Auteur ; Allison JACK, Auteur ; Shafali JESTE, Auteur ; James C. MCPARTLAND, Auteur ; Adam NAPLES, Auteur ; John D. VAN HORN, Auteur ; Kevin A. PELPHREY, Auteur ; Sara Jane WEBB, Auteur Article en page(s) : 19p. Langues : Anglais (eng) Mots-clés : Humans  Autism Spectrum Disorder/physiopathology/psychology  Male  Female  Adolescent  Gamma Rhythm  Child  Electroencephalography  Language  Family  Siblings  Autism Spectrum Disorder (ASD)  Excitation/inhibition balance  Gamma power  Language skills  Unaffected siblings  Health, and BlackThorn Therapeutics, has received research funding from Janssen  Research and Development, serves on the Scientific Advisory Boards of Pastorus  and Modern Clinics, and receives royalties from Guilford Press, Lambert, Oxford,  and Springer. The remaining authors have no conflict of interest to declare. Index. décimale : PER Périodiques Résumé : BACKGROUND: Most children with Autism Spectrum Disorder (ASD) have co-occurring language impairments and some of these autism-specific language difficulties are also present in their non-autistic first-degree relatives. One of the possible neural mechanisms associated with variability in language functioning is alterations in cortical gamma-band oscillations, hypothesized to be related to neural excitation and inhibition balance. METHODS: We used a high-density 128-channel electroencephalography (EEG) to register brain response to speech stimuli in a large sex-balanced sample of participants: 125 youth with ASD, 121 typically developing (TD) youth, and 40 unaffected siblings (US) of youth with ASD. Language skills were assessed with Clinical Evaluation of Language Fundamentals. RESULTS: First, during speech processing, we identified significantly elevated gamma power in ASD participants compared to TD controls. Second, across all youth, higher gamma power was associated with lower language skills. Finally, the US group demonstrated an intermediate profile in both language and gamma power, with nonverbal IQ mediating the relationship between gamma power and language skills. LIMITATIONS: We only focused on one of the possible neural contributors to variability in language functioning. Also, the US group consisted of a smaller number of participants in comparison to the ASD or TD groups. Finally, due to the timing issue in EEG system we have provided only non-phase-locked analysis. CONCLUSIONS: Autistic youth showed elevated gamma power, suggesting higher excitation in the brain in response to speech stimuli and elevated gamma power was related to lower language skills. The US group showed an intermediate pattern of gamma activity, suggesting that the broader autism phenotype extends to neural profiles. En ligne : https://dx.doi.org/10.1186/s13229-024-00598-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=538 [article] The relationship between gamma-band neural oscillations and language skills in youth with Autism Spectrum Disorder and their first-degree relatives [Texte imprimé et/ou numérique] / Vardan ARUTIUNIAN, Auteur ; Megha SANTHOSH, Auteur ; Emily NEUHAUS, Auteur ; Heather BORLAND, Auteur ; Chris TOMPKINS, Auteur ; Raphael A. BERNIER, Auteur ; Susan Y. BOOKHEIMER, Auteur ; Mirella DAPRETTO, Auteur ; Abha R. GUPTA, Auteur ; Allison JACK, Auteur ; Shafali JESTE, Auteur ; James C. MCPARTLAND, Auteur ; Adam NAPLES, Auteur ; John D. VAN HORN, Auteur ; Kevin A. PELPHREY, Auteur ; Sara Jane WEBB, Auteur . - 19p. Langues : Anglais (eng) in Molecular Autism > 15 (2024) . - 19p. Mots-clés : Humans  Autism Spectrum Disorder/physiopathology/psychology  Male  Female  Adolescent  Gamma Rhythm  Child  Electroencephalography  Language  Family  Siblings  Autism Spectrum Disorder (ASD)  Excitation/inhibition balance  Gamma power  Language skills  Unaffected siblings  Health, and BlackThorn Therapeutics, has received research funding from Janssen  Research and Development, serves on the Scientific Advisory Boards of Pastorus  and Modern Clinics, and receives royalties from Guilford Press, Lambert, Oxford,  and Springer. The remaining authors have no conflict of interest to declare. Index. décimale : PER Périodiques Résumé : BACKGROUND: Most children with Autism Spectrum Disorder (ASD) have co-occurring language impairments and some of these autism-specific language difficulties are also present in their non-autistic first-degree relatives. One of the possible neural mechanisms associated with variability in language functioning is alterations in cortical gamma-band oscillations, hypothesized to be related to neural excitation and inhibition balance. METHODS: We used a high-density 128-channel electroencephalography (EEG) to register brain response to speech stimuli in a large sex-balanced sample of participants: 125 youth with ASD, 121 typically developing (TD) youth, and 40 unaffected siblings (US) of youth with ASD. Language skills were assessed with Clinical Evaluation of Language Fundamentals. RESULTS: First, during speech processing, we identified significantly elevated gamma power in ASD participants compared to TD controls. Second, across all youth, higher gamma power was associated with lower language skills. Finally, the US group demonstrated an intermediate profile in both language and gamma power, with nonverbal IQ mediating the relationship between gamma power and language skills. LIMITATIONS: We only focused on one of the possible neural contributors to variability in language functioning. Also, the US group consisted of a smaller number of participants in comparison to the ASD or TD groups. Finally, due to the timing issue in EEG system we have provided only non-phase-locked analysis. CONCLUSIONS: Autistic youth showed elevated gamma power, suggesting higher excitation in the brain in response to speech stimuli and elevated gamma power was related to lower language skills. The US group showed an intermediate pattern of gamma activity, suggesting that the broader autism phenotype extends to neural profiles. En ligne : https://dx.doi.org/10.1186/s13229-024-00598-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=538

Visual Preference for Biological Motion in Children and Adults with Autism Spectrum Disorder: An Eye-Tracking Study / Dzmitry A. KALIUKHOVICH in Journal of Autism and Developmental Disorders, 51-7 (July 2021)  

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Olfactory processing in adults with autism spectrum disorders / B. WICKER in Molecular Autism, 7 (2016)  

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Assessment of olfactory detection thresholds in children with autism spectrum disorders using a pulse ejection system / H. KUMAZAKI in Molecular Autism, 7 (2016)  

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Bengali translation and characterisation of four cognitive and trait measures for autism spectrum conditions in India / A. RUDRA in Molecular Autism, 7 (2016)  

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Development of the Social Motor Function Classification System for Children with Autism Spectrum Disorders: A Psychometric Study / T. W. PIN in Journal of Autism and Developmental Disorders, 51-6 (June 2021)  

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