Autism spectrum disorder in Qatar: Profiles and correlates of a large clinical sample / Fouad ALSHABAN in Autism & Developmental Language Impairments, 2 (January-December 2017)  

Public ISBD [article]  inAutism & Developmental Language Impairments > 2 (January-December 2017) Titre : Autism spectrum disorder in Qatar: Profiles and correlates of a large clinical sample Type de document : Texte imprimé et/ou numérique Auteurs : Fouad ALSHABAN, Auteur ; Mohammed ALDOSARI, Auteur ; Zakaria EL SAYED, Auteur ; Mohammed TOLEFAT, Auteur ; Saba EL HAG, Auteur ; Hawra AL SHAMMARI, Auteur ; Iman GHAZAL, Auteur ; Eric FOMBONNE, Auteur Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is an increasingly prevalent disorder. Although around 15% of cases are caused by specific genetic causes, most cases involve a complex and variable combination of genetic risk and environmental factors that are not yet identified. There is a paucity of studies on ASD in Qatar, mostly in the form of case reports and genetic causes. The current study was designed to describe the clinical characteristics of ASD and its correlates in Qatar. Individuals with ASD were recruited from the Shafallah Center for Children with Special Needs which is the largest special needs center in Qatar. Within the sample of 171 individuals with ASD, 47% were ethnic Qataris, while 53% were nonethnic Qataris (Arabs and other nationalities). The analysis included the following factors: nationality, age, gender, socioeconomic status, consanguinity, prenatal/postnatal complications, and comorbidities. Eighty percent of the identified cases were males, with a 4:1 male to female ratio. Additionally, 83% of the families had one proband, 9.9% with 2 probands, and 7.1% with more than two. Comorbid conditions included: intellectual disabilities (ID) in 83% and epilepsy in 18.8%. 76.6% of subjects were nonverbal. There were 3 (1.8%) children with Rett?s syndrome, 3 (1.8%) with Fragile X, and 1 (0.6%) with tuberous sclerosis. There are currently no publications that clarify the mean age of diagnosis in Qatar, however, the present study showed that more than half of the diagnosed cases were among the ages of 7?14 years (56%). The effect of consanguinity as a risk factor was not found to be significant. En ligne : https://doi.org/10.1177/2396941517699215 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=386 [article] Autism spectrum disorder in Qatar: Profiles and correlates of a large clinical sample [Texte imprimé et/ou numérique] / Fouad ALSHABAN, Auteur ; Mohammed ALDOSARI, Auteur ; Zakaria EL SAYED, Auteur ; Mohammed TOLEFAT, Auteur ; Saba EL HAG, Auteur ; Hawra AL SHAMMARI, Auteur ; Iman GHAZAL, Auteur ; Eric FOMBONNE, Auteur. Langues : Anglais (eng) in Autism & Developmental Language Impairments > 2 (January-December 2017) Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is an increasingly prevalent disorder. Although around 15% of cases are caused by specific genetic causes, most cases involve a complex and variable combination of genetic risk and environmental factors that are not yet identified. There is a paucity of studies on ASD in Qatar, mostly in the form of case reports and genetic causes. The current study was designed to describe the clinical characteristics of ASD and its correlates in Qatar. Individuals with ASD were recruited from the Shafallah Center for Children with Special Needs which is the largest special needs center in Qatar. Within the sample of 171 individuals with ASD, 47% were ethnic Qataris, while 53% were nonethnic Qataris (Arabs and other nationalities). The analysis included the following factors: nationality, age, gender, socioeconomic status, consanguinity, prenatal/postnatal complications, and comorbidities. Eighty percent of the identified cases were males, with a 4:1 male to female ratio. Additionally, 83% of the families had one proband, 9.9% with 2 probands, and 7.1% with more than two. Comorbid conditions included: intellectual disabilities (ID) in 83% and epilepsy in 18.8%. 76.6% of subjects were nonverbal. There were 3 (1.8%) children with Rett?s syndrome, 3 (1.8%) with Fragile X, and 1 (0.6%) with tuberous sclerosis. There are currently no publications that clarify the mean age of diagnosis in Qatar, however, the present study showed that more than half of the diagnosed cases were among the ages of 7?14 years (56%). The effect of consanguinity as a risk factor was not found to be significant. En ligne : https://doi.org/10.1177/2396941517699215 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=386

Development and validation of an Arabic language eye-tracking paradigm for the early screening and diagnosis of autism spectrum disorders in Qatar / Iman GHAZAL ; I. Richard THOMPSON ; Eric W. KLINGEMIER ; Mohammed ALDOSARI ; Hawraa AL-SHAMMARI ; Fatema AL-FARAJ ; Saba EL-HAG ; Mohamed TOLEFAT ; Mogahed ALI ; Bisher NASIR ; Thomas W. FRAZIER in Autism Research, 16-12 (December 2023)  

Public ISBD [article]  inAutism Research > 16-12 (December 2023) . - p.2291-2301 Titre : Development and validation of an Arabic language eye-tracking paradigm for the early screening and diagnosis of autism spectrum disorders in Qatar Type de document : Texte imprimé et/ou numérique Auteurs : Iman GHAZAL, Auteur ; I. Richard THOMPSON, Auteur ; Eric W. KLINGEMIER, Auteur ; Mohammed ALDOSARI, Auteur ; Hawraa AL-SHAMMARI, Auteur ; Fatema AL-FARAJ, Auteur ; Saba EL-HAG, Auteur ; Mohamed TOLEFAT, Auteur ; Mogahed ALI, Auteur ; Bisher NASIR, Auteur ; Thomas W. FRAZIER, Auteur Article en page(s) : p.2291-2301 Index. décimale : PER Périodiques Résumé : Abstract Abnormal eye gaze is a hallmark characteristic of autism spectrum disorder (ASD). The primary aim of the present research was to develop an Arabic version of an objective measure of ASD, the "autism index" (AI), based on eye gaze tracking to social and nonsocial stimuli validated initially in the United States. The initial phase of this study included the translation of English language eye-tracking stimuli into stimuli appropriate for an Arabic-speaking culture. During the second phase, we tested it on a total of 144 children with ASD, and 96 controls. The AI had excellent internal consistency and test-retest reliability. Moreover, the AI showed good differentiation of ASD from control cases (AUC = 0.730, SE = 0.035). The AI was significantly positively correlated with SCQ total raw scores (r = 0.46, p<0.001). ADOS-2 scores were only available in the ASD group and did not show a significant relationship with AI scores (r = 0.10, p = 0.348), likely due to the restricted range. The AI, when implemented using Arabic-translated stimuli in a Qatari sample, showed good diagnostic differentiation and a strong correlation with parent-reported ASD symptoms. Thus, the AI appears to have cross-cultural validity and may be useful as a diagnostic aide to inform clinical judgment and track ASD symptom levels as part of the evaluation process. En ligne : https://doi.org/10.1002/aur.3046 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=518 [article] Development and validation of an Arabic language eye-tracking paradigm for the early screening and diagnosis of autism spectrum disorders in Qatar [Texte imprimé et/ou numérique] / Iman GHAZAL, Auteur ; I. Richard THOMPSON, Auteur ; Eric W. KLINGEMIER, Auteur ; Mohammed ALDOSARI, Auteur ; Hawraa AL-SHAMMARI, Auteur ; Fatema AL-FARAJ, Auteur ; Saba EL-HAG, Auteur ; Mohamed TOLEFAT, Auteur ; Mogahed ALI, Auteur ; Bisher NASIR, Auteur ; Thomas W. FRAZIER, Auteur . - p.2291-2301. in Autism Research > 16-12 (December 2023) . - p.2291-2301 Index. décimale : PER Périodiques Résumé : Abstract Abnormal eye gaze is a hallmark characteristic of autism spectrum disorder (ASD). The primary aim of the present research was to develop an Arabic version of an objective measure of ASD, the "autism index" (AI), based on eye gaze tracking to social and nonsocial stimuli validated initially in the United States. The initial phase of this study included the translation of English language eye-tracking stimuli into stimuli appropriate for an Arabic-speaking culture. During the second phase, we tested it on a total of 144 children with ASD, and 96 controls. The AI had excellent internal consistency and test-retest reliability. Moreover, the AI showed good differentiation of ASD from control cases (AUC = 0.730, SE = 0.035). The AI was significantly positively correlated with SCQ total raw scores (r = 0.46, p<0.001). ADOS-2 scores were only available in the ASD group and did not show a significant relationship with AI scores (r = 0.10, p = 0.348), likely due to the restricted range. The AI, when implemented using Arabic-translated stimuli in a Qatari sample, showed good diagnostic differentiation and a strong correlation with parent-reported ASD symptoms. Thus, the AI appears to have cross-cultural validity and may be useful as a diagnostic aide to inform clinical judgment and track ASD symptom levels as part of the evaluation process. En ligne : https://doi.org/10.1002/aur.3046 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=518

---

1 (1 - 2 / 2)