Autism spectrum disorder: An examination of sex differences in neuropsychological and self-report measures of executive and non-executive cognitive function / Eleni A. DEMETRIOU in Autism, 25-8 (November 2021)  

Public ISBD [article]  inAutism > 25-8 (November 2021) . - p.2223-2237 Titre : Autism spectrum disorder: An examination of sex differences in neuropsychological and self-report measures of executive and non-executive cognitive function Type de document : Texte imprimé et/ou numérique Auteurs : Eleni A. DEMETRIOU, Auteur ; K. L. PEPPER, Auteur ; S. H. PARK, Auteur ; L. PELLICANO, Auteur ; Y. J. C. SONG, Auteur ; S. L. NAISMITH, Auteur ; I. B. HICKIE, Auteur ; E. E. THOMAS, Auteur ; A. J. GUASTELLA, Auteur Article en page(s) : p.2223-2237 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/diagnosis  Autistic Disorder  Cognition  Executive Function  Female  Humans  Male  Neuropsychological Tests  Self Report  Sex Characteristics  Behavioural Rating Inventory of Executive Function  Cambridge Neuropsychological Test Automated Battery  autism spectrum disorder  executive function  sex differences Index. décimale : PER Périodiques Résumé : Research comparing females and males with a diagnosis of autism suggests that there are sex differences in some characteristics such as behaviour regulation. One area not studied in detail is whether females and males with autism perform differently in tests of cognitive ability. The results of previous research are quite mixed. One explanation may be that some research comparing females and males with autism did not include a neurotypical control group for comparison. As a result, it is not clear whether the sex differences in cognitive ability observed in people with autism are similar to differences between neurotypical males and females. To better understand whether there are unique differences between males and females with autism, it is important to also compare them with neurotypical males and females. In our research, we included a neurotypical group and compared males and females with and without a diagnosis of autism. We found that the sex differences in autism are similar to what we observe in males and females without autism. Our study showed that compared with males, females (with and without autism) do better in assessments of processing speed, cognitive flexibility, verbal learning and memory and semantic fluency. Our results suggest that although females show different cognitive performance to males, these sex differences were not specific to the group with a diagnosis of autism. En ligne : http://dx.doi.org/10.1177/13623613211014991 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=451 [article] Autism spectrum disorder: An examination of sex differences in neuropsychological and self-report measures of executive and non-executive cognitive function [Texte imprimé et/ou numérique] / Eleni A. DEMETRIOU, Auteur ; K. L. PEPPER, Auteur ; S. H. PARK, Auteur ; L. PELLICANO, Auteur ; Y. J. C. SONG, Auteur ; S. L. NAISMITH, Auteur ; I. B. HICKIE, Auteur ; E. E. THOMAS, Auteur ; A. J. GUASTELLA, Auteur . - p.2223-2237. Langues : Anglais (eng) in Autism > 25-8 (November 2021) . - p.2223-2237 Mots-clés : Autism Spectrum Disorder/diagnosis  Autistic Disorder  Cognition  Executive Function  Female  Humans  Male  Neuropsychological Tests  Self Report  Sex Characteristics  Behavioural Rating Inventory of Executive Function  Cambridge Neuropsychological Test Automated Battery  autism spectrum disorder  executive function  sex differences Index. décimale : PER Périodiques Résumé : Research comparing females and males with a diagnosis of autism suggests that there are sex differences in some characteristics such as behaviour regulation. One area not studied in detail is whether females and males with autism perform differently in tests of cognitive ability. The results of previous research are quite mixed. One explanation may be that some research comparing females and males with autism did not include a neurotypical control group for comparison. As a result, it is not clear whether the sex differences in cognitive ability observed in people with autism are similar to differences between neurotypical males and females. To better understand whether there are unique differences between males and females with autism, it is important to also compare them with neurotypical males and females. In our research, we included a neurotypical group and compared males and females with and without a diagnosis of autism. We found that the sex differences in autism are similar to what we observe in males and females without autism. Our study showed that compared with males, females (with and without autism) do better in assessments of processing speed, cognitive flexibility, verbal learning and memory and semantic fluency. Our results suggest that although females show different cognitive performance to males, these sex differences were not specific to the group with a diagnosis of autism. En ligne : http://dx.doi.org/10.1177/13623613211014991 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=451

Disability, functioning, and quality of life among treatment-seeking young autistic adults and its relation to depression, anxiety, and stress / S. H. PARK in Autism, 23-7 (October 2019)  

Public ISBD [article]  inAutism > 23-7 (October 2019) . - p.1675-1686 Titre : Disability, functioning, and quality of life among treatment-seeking young autistic adults and its relation to depression, anxiety, and stress Type de document : Texte imprimé et/ou numérique Auteurs : S. H. PARK, Auteur ; Y. J. C. SONG, Auteur ; Eleni A. DEMETRIOU, Auteur ; K. L. PEPPER, Auteur ; A. NORTON, Auteur ; E. E. THOMAS, Auteur ; I. B. HICKIE, Auteur ; D. F. HERMENS, Auteur ; N. GLOZIER, Auteur ; A. J. GUASTELLA, Auteur Article en page(s) : p.1675-1686 Langues : Anglais (eng) Mots-clés : developmental disorders  distress  health services  mental health  treatment  well being Index. décimale : PER Périodiques Résumé : In this study, we consecutively recruited treatment-seeking young autistic adults without intellectual impairment aged 16-30 years who presented to a mental health service and evaluated general health (distress, quality of life, and disability), functioning (work loss days and social functioning), and mood symptoms (depression, anxiety, and stress) in those diagnosed with autism spectrum disorder (n = 96). This group was compared to young adults presenting to the same service with primary mental health disorders (depression, n = 343; bipolar, n = 132; psychosis, n = 166; and anxiety, n = 303). This study also investigated the influence of mood symptoms on general health and functioning in the autism spectrum disorder group. Young autistic adults reported significant general health and functioning impairments that were of similar degree to those presenting with primary mental health disorders. Interestingly, the autistic group also reported similarly high levels of mood symptoms to those with primary depressive and anxiety disorders. In the autistic group, depressive symptoms were strongly associated with distress, quality of life, and work loss days, while stress symptoms were strongly associated with disability. This study highlights further research, and mental health services are required specifically targeting young autistic adults to address their significant unmet needs. En ligne : http://dx.doi.org/10.1177/1362361318823925 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=406 [article] Disability, functioning, and quality of life among treatment-seeking young autistic adults and its relation to depression, anxiety, and stress [Texte imprimé et/ou numérique] / S. H. PARK, Auteur ; Y. J. C. SONG, Auteur ; Eleni A. DEMETRIOU, Auteur ; K. L. PEPPER, Auteur ; A. NORTON, Auteur ; E. E. THOMAS, Auteur ; I. B. HICKIE, Auteur ; D. F. HERMENS, Auteur ; N. GLOZIER, Auteur ; A. J. GUASTELLA, Auteur . - p.1675-1686. Langues : Anglais (eng) in Autism > 23-7 (October 2019) . - p.1675-1686 Mots-clés : developmental disorders  distress  health services  mental health  treatment  well being Index. décimale : PER Périodiques Résumé : In this study, we consecutively recruited treatment-seeking young autistic adults without intellectual impairment aged 16-30 years who presented to a mental health service and evaluated general health (distress, quality of life, and disability), functioning (work loss days and social functioning), and mood symptoms (depression, anxiety, and stress) in those diagnosed with autism spectrum disorder (n = 96). This group was compared to young adults presenting to the same service with primary mental health disorders (depression, n = 343; bipolar, n = 132; psychosis, n = 166; and anxiety, n = 303). This study also investigated the influence of mood symptoms on general health and functioning in the autism spectrum disorder group. Young autistic adults reported significant general health and functioning impairments that were of similar degree to those presenting with primary mental health disorders. Interestingly, the autistic group also reported similarly high levels of mood symptoms to those with primary depressive and anxiety disorders. In the autistic group, depressive symptoms were strongly associated with distress, quality of life, and work loss days, while stress symptoms were strongly associated with disability. This study highlights further research, and mental health services are required specifically targeting young autistic adults to address their significant unmet needs. En ligne : http://dx.doi.org/10.1177/1362361318823925 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=406

Replication of the psychometric properties of the WHODAS-II in individuals with autism spectrum disorder / S. H. PARK in Autism Research, 12-12 (December)  

Public ISBD [article]  inAutism Research > 12-12 (December) . - p.1726-1727 Titre : Replication of the psychometric properties of the WHODAS-II in individuals with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : S. H. PARK, Auteur ; Eleni A. DEMETRIOU, Auteur ; K. L. PEPPER, Auteur ; Y. J. C. SONG, Auteur ; E. E. THOMAS, Auteur ; I. B. HICKIE, Auteur ; N. GLOZIER, Auteur ; A. J. GUASTELLA, Auteur Année de publication : 2019 Article en page(s) : p.1726-1727 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.2216 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413 [article] Replication of the psychometric properties of the WHODAS-II in individuals with autism spectrum disorder [Texte imprimé et/ou numérique] / S. H. PARK, Auteur ; Eleni A. DEMETRIOU, Auteur ; K. L. PEPPER, Auteur ; Y. J. C. SONG, Auteur ; E. E. THOMAS, Auteur ; I. B. HICKIE, Auteur ; N. GLOZIER, Auteur ; A. J. GUASTELLA, Auteur . - 2019 . - p.1726-1727. Langues : Anglais (eng) in Autism Research > 12-12 (December) . - p.1726-1727 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1002/aur.2216 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=413

The Feasibility of Magnetic Resonance Imaging in a Non-Selective Comprehensive Clinical Trial in Pediatric Autism Spectrum Disorder / Marilena M. DEMAYO in Journal of Autism and Developmental Disorders, 52-3 (March 2022)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 52-3 (March 2022) . - p.1211-1222 Titre : The Feasibility of Magnetic Resonance Imaging in a Non-Selective Comprehensive Clinical Trial in Pediatric Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Marilena M. DEMAYO, Auteur ; I. POKORSKI, Auteur ; Y. J. C. SONG, Auteur ; R. THAPA, Auteur ; S. PATEL, Auteur ; Zahava AMBARCHI, Auteur ; D. SOLIGO, Auteur ; I. SADELI, Auteur ; E. E. THOMAS, Auteur ; I. B. HICKIE, Auteur ; A. J. GUASTELLA, Auteur Article en page(s) : p.1211-1222 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/diagnostic imaging  Brain  Child  Child, Preschool  Feasibility Studies  Humans  Magnetic Resonance Imaging/methods  Autism spectrum disorders  Biomarkers  Brain function  Brain structure  Clinical trial  Interventions–pharmacologic  Magnetic resonance imaging  Neuroimaging  Pre-school children  School-age children Index. décimale : PER Périodiques Résumé : There is an increasing interest in using magnetic resonance imaging (MRI) as a tool for precision medicine in autism spectrum disorder (ASD). This study investigated the feasibility of MRI scanning in a large comprehensive, inclusive and test heavy clinical trial for children (aged 3-12 years) with ASD, without functioning constraints for participation. Of the 71 participants enrolled who consented to the MRI, 24 participants (38%) successfully completed an MRI scan at baseline along with other assessments. This scanning followed a familiarization procedure at two preceding visits. At post-treatment, 21 participants successfully completed the MRI scan. This study highlights the challenge of completing MRI assessments in ASD populations when conducted as one of a number of tests in a clinical trial. En ligne : http://dx.doi.org/10.1007/s10803-021-05028-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=455 [article] The Feasibility of Magnetic Resonance Imaging in a Non-Selective Comprehensive Clinical Trial in Pediatric Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Marilena M. DEMAYO, Auteur ; I. POKORSKI, Auteur ; Y. J. C. SONG, Auteur ; R. THAPA, Auteur ; S. PATEL, Auteur ; Zahava AMBARCHI, Auteur ; D. SOLIGO, Auteur ; I. SADELI, Auteur ; E. E. THOMAS, Auteur ; I. B. HICKIE, Auteur ; A. J. GUASTELLA, Auteur . - p.1211-1222. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 52-3 (March 2022) . - p.1211-1222 Mots-clés : Autism Spectrum Disorder/diagnostic imaging  Brain  Child  Child, Preschool  Feasibility Studies  Humans  Magnetic Resonance Imaging/methods  Autism spectrum disorders  Biomarkers  Brain function  Brain structure  Clinical trial  Interventions–pharmacologic  Magnetic resonance imaging  Neuroimaging  Pre-school children  School-age children Index. décimale : PER Périodiques Résumé : There is an increasing interest in using magnetic resonance imaging (MRI) as a tool for precision medicine in autism spectrum disorder (ASD). This study investigated the feasibility of MRI scanning in a large comprehensive, inclusive and test heavy clinical trial for children (aged 3-12 years) with ASD, without functioning constraints for participation. Of the 71 participants enrolled who consented to the MRI, 24 participants (38%) successfully completed an MRI scan at baseline along with other assessments. This scanning followed a familiarization procedure at two preceding visits. At post-treatment, 21 participants successfully completed the MRI scan. This study highlights the challenge of completing MRI assessments in ASD populations when conducted as one of a number of tests in a clinical trial. En ligne : http://dx.doi.org/10.1007/s10803-021-05028-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=455

Validation of the 36-item and 12-item self-report World Health Organization Disability Assessment Schedule II (WHODAS-II) in individuals with autism spectrum disorder / S. H. PARK in Autism Research, 12-7 (July 2019)  

Public ISBD [article]  inAutism Research > 12-7 (July 2019) . - p.1101-1111 Titre : Validation of the 36-item and 12-item self-report World Health Organization Disability Assessment Schedule II (WHODAS-II) in individuals with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : S. H. PARK, Auteur ; Eleni A. DEMETRIOU, Auteur ; K. L. PEPPER, Auteur ; Y. J. C. SONG, Auteur ; E. E. THOMAS, Auteur ; I. B. HICKIE, Auteur ; N. GLOZIER, Auteur ; A. J. GUASTELLA, Auteur Année de publication : 2019 Article en page(s) : p.1101-1111 Langues : Anglais (eng) Mots-clés : Whodas  autism spectrum disorder  disability  internal consistency  validity Index. décimale : PER Périodiques Résumé : The World Health Organization Disability Assessment Schedule II (WHODAS-II) is one of the most widely used generic assessments for measuring disability levels in both clinical and nonclinical populations, with sound psychometrics that is also aligned with the International Classification of Functioning framework. However, its psychometric properties have not been explored extensively in individuals with autism spectrum disorder (ASD). This study examined the psychometric properties of the 36-item and 12-item Self-Report WHODAS-II from 109 individuals diagnosed with ASD and without intellectual disability (IQ >/= 70). Participants were consecutively recruited from the Brain and Mind Centre in New South Wales, Australia. The WHODAS-II showed adequate internal consistency for all domain scores (alpha = 0.78-0.97 for 36-item) and for the summary scale (alpha = 0.95 for 36-item; 0.86 for 12-item). All items also exhibited satisfactory correlations with their respective domain (r = 0.39-0.94 for 36-item) and summary scores (r = 0.42-0.71 for 36-item; 0.42-0.67 for 12-item), except item 4.5 "sexual activity" from the 36-item WHODAS-II (r = 0.19). Concurrent validity was shown by moderate correlations between similar constructs across the WHODAS-II and the World Health Organization Quality of Life BREF (Ps < 0.05). The second-order 7-factor model showed the best fit for the 36-item WHODAS-II, while the second-order 6-factor model demonstrated an acceptable fit for the 12-item WHODAS-II. The model fit could be improved with some modifications. The Schmid-Leiman transformation further confirmed the appropriateness of the second-order factor structure. Overall, the results indicated that the WHODAS-II is a viable generic self-report measure for disability in autistic individuals without ID. Autism Res 2019, 12: 1101-1111. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: The majority of autistic people have a disability with a profound or severe limitation in their core activities. However, there is currently limited research identifying reliable and valid self-report measures for disability in the autistic population. This study examined the psychometric properties of the World Health Organization Disability Assessment Schedule II (WHODAS-II) from 109 autistic individuals without intellectual disability. Our results suggest that the WHODAS-II is a viable generic self-report measure for disability in autistic individuals. En ligne : http://dx.doi.org/10.1002/aur.2115 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=402 [article] Validation of the 36-item and 12-item self-report World Health Organization Disability Assessment Schedule II (WHODAS-II) in individuals with autism spectrum disorder [Texte imprimé et/ou numérique] / S. H. PARK, Auteur ; Eleni A. DEMETRIOU, Auteur ; K. L. PEPPER, Auteur ; Y. J. C. SONG, Auteur ; E. E. THOMAS, Auteur ; I. B. HICKIE, Auteur ; N. GLOZIER, Auteur ; A. J. GUASTELLA, Auteur . - 2019 . - p.1101-1111. Langues : Anglais (eng) in Autism Research > 12-7 (July 2019) . - p.1101-1111 Mots-clés : Whodas  autism spectrum disorder  disability  internal consistency  validity Index. décimale : PER Périodiques Résumé : The World Health Organization Disability Assessment Schedule II (WHODAS-II) is one of the most widely used generic assessments for measuring disability levels in both clinical and nonclinical populations, with sound psychometrics that is also aligned with the International Classification of Functioning framework. However, its psychometric properties have not been explored extensively in individuals with autism spectrum disorder (ASD). This study examined the psychometric properties of the 36-item and 12-item Self-Report WHODAS-II from 109 individuals diagnosed with ASD and without intellectual disability (IQ >/= 70). Participants were consecutively recruited from the Brain and Mind Centre in New South Wales, Australia. The WHODAS-II showed adequate internal consistency for all domain scores (alpha = 0.78-0.97 for 36-item) and for the summary scale (alpha = 0.95 for 36-item; 0.86 for 12-item). All items also exhibited satisfactory correlations with their respective domain (r = 0.39-0.94 for 36-item) and summary scores (r = 0.42-0.71 for 36-item; 0.42-0.67 for 12-item), except item 4.5 "sexual activity" from the 36-item WHODAS-II (r = 0.19). Concurrent validity was shown by moderate correlations between similar constructs across the WHODAS-II and the World Health Organization Quality of Life BREF (Ps < 0.05). The second-order 7-factor model showed the best fit for the 36-item WHODAS-II, while the second-order 6-factor model demonstrated an acceptable fit for the 12-item WHODAS-II. The model fit could be improved with some modifications. The Schmid-Leiman transformation further confirmed the appropriateness of the second-order factor structure. Overall, the results indicated that the WHODAS-II is a viable generic self-report measure for disability in autistic individuals without ID. Autism Res 2019, 12: 1101-1111. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: The majority of autistic people have a disability with a profound or severe limitation in their core activities. However, there is currently limited research identifying reliable and valid self-report measures for disability in the autistic population. This study examined the psychometric properties of the World Health Organization Disability Assessment Schedule II (WHODAS-II) from 109 autistic individuals without intellectual disability. Our results suggest that the WHODAS-II is a viable generic self-report measure for disability in autistic individuals. En ligne : http://dx.doi.org/10.1002/aur.2115 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=402

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