Exploring trajectories of anxiety symptoms in autistic and non-autistic youth over adolescence using parent- and self-report measures / Meredith COLA in Research in Autism, 132 (April 2026)  

Public ISBD [article]  inResearch in Autism > 132 (April 2026) . - 202830 Titre : Exploring trajectories of anxiety symptoms in autistic and non-autistic youth over adolescence using parent- and self-report measures Type de document : texte imprimé Auteurs : Meredith COLA, Auteur ; Rachael A. MUSCATELLO, Auteur ; Xinyu ZHANG, Auteur ; Simon VANDEKAR, Auteur ; Trey MCGONIGLE, Auteur ; Blythe A. CORBETT, Auteur Article en page(s) : 202830 Langues : Anglais (eng) Mots-clés : Autism  Adolescence  Anxiety  Puberty  Development Résumé : Background Autistic youth frequently experience co-occurring anxiety. In non-autistic populations, females are more likely to be diagnosed with anxiety and demonstrate distinct symptom trajectories across adolescence. Prior research has demonstrated diagnostic group differences in parent- and self-reported anxiety symptoms; however, it is largely unknown if and how symptoms change over puberty. We examine trajectories of anxiety symptoms for autistic and non-autistic youth over a four-year (Y1-Y4) longitudinal study. Methods Autistic (N = 140) and non-autistic (N = 104) youth (ages 10–13 years at Y1) completed the parent- and self-report versions of the Multidimensional Anxiety Scale for Children, 2nd Edition (MASC-2). Linear mixed effects models were used to examine the impact of age, sex, and diagnosis on anxiety symptoms. Results There was a significant diagnosis-sex interaction (pFDR=0.005) on the parent-report of anxiety and a main effect of age (p < 0.001). Autistic and non-autistic females showed an increase in anxiety symptoms over time; autistic males showed a slight decrease. There was a main effect of diagnosis (pFDR=0.003) on the child-report measure of anxiety symptoms; the effects of age (pFDR=0.117) and sex were not significant (pFDR=0.305). The relationship between pubertal development and anxiety symptoms differed between the subgroups. Conclusions Our main findings – that autistic youth demonstrate greater anxiety symptoms than non-autistic youth, with distinct symptom trajectories emerging in females versus males – add to the growing literature aimed at understanding the biopsychosocial factors impacting puberty and emotional functioning across adolescence. En ligne : https://doi.org/10.1016/j.reia.2026.202830 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=583 [article] Exploring trajectories of anxiety symptoms in autistic and non-autistic youth over adolescence using parent- and self-report measures [texte imprimé] / Meredith COLA, Auteur ; Rachael A. MUSCATELLO, Auteur ; Xinyu ZHANG, Auteur ; Simon VANDEKAR, Auteur ; Trey MCGONIGLE, Auteur ; Blythe A. CORBETT, Auteur . - 202830. Langues : Anglais (eng) in Research in Autism > 132 (April 2026) . - 202830 Mots-clés : Autism  Adolescence  Anxiety  Puberty  Development Résumé : Background Autistic youth frequently experience co-occurring anxiety. In non-autistic populations, females are more likely to be diagnosed with anxiety and demonstrate distinct symptom trajectories across adolescence. Prior research has demonstrated diagnostic group differences in parent- and self-reported anxiety symptoms; however, it is largely unknown if and how symptoms change over puberty. We examine trajectories of anxiety symptoms for autistic and non-autistic youth over a four-year (Y1-Y4) longitudinal study. Methods Autistic (N = 140) and non-autistic (N = 104) youth (ages 10–13 years at Y1) completed the parent- and self-report versions of the Multidimensional Anxiety Scale for Children, 2nd Edition (MASC-2). Linear mixed effects models were used to examine the impact of age, sex, and diagnosis on anxiety symptoms. Results There was a significant diagnosis-sex interaction (pFDR=0.005) on the parent-report of anxiety and a main effect of age (p < 0.001). Autistic and non-autistic females showed an increase in anxiety symptoms over time; autistic males showed a slight decrease. There was a main effect of diagnosis (pFDR=0.003) on the child-report measure of anxiety symptoms; the effects of age (pFDR=0.117) and sex were not significant (pFDR=0.305). The relationship between pubertal development and anxiety symptoms differed between the subgroups. Conclusions Our main findings – that autistic youth demonstrate greater anxiety symptoms than non-autistic youth, with distinct symptom trajectories emerging in females versus males – add to the growing literature aimed at understanding the biopsychosocial factors impacting puberty and emotional functioning across adolescence. En ligne : https://doi.org/10.1016/j.reia.2026.202830 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=583

Pubertal developmental, body mass index, and cardiovascular autonomic function in children and adolescents with and without autism spectrum disorder: a four-time point accelerated longitudinal study / Rachael A. MUSCATELLO in Journal of Neurodevelopmental Disorders, 17 (2025)  

Public ISBD [article]  inJournal of Neurodevelopmental Disorders > 17 (2025) Titre : Pubertal developmental, body mass index, and cardiovascular autonomic function in children and adolescents with and without autism spectrum disorder: a four-time point accelerated longitudinal study Type de document : texte imprimé Auteurs : Rachael A. MUSCATELLO, Auteur ; Meredith COLA, Auteur ; Simon VANDEKAR, Auteur ; Blythe A. CORBETT, Auteur Langues : Anglais (eng) Mots-clés : Humans  Adolescent  Child  Male  Female  Autism Spectrum Disorder/physiopathology  Longitudinal Studies  Body Mass Index  Autonomic Nervous System/physiopathology  Puberty/physiology  Heart Rate/physiology  Respiratory Sinus Arrhythmia/physiology  Autism  Autonomic  Cardiovascular  Health  Heart rate  Physical  Pubertal development  Variability  out in accordance with the Code of Ethics of the World Medical Association  (Declaration of Helsinki). The Vanderbilt Institutional Review Board approved all  study procedures. In compliance with the Institutional Review Board, informed  written consent and verbal assent was obtained from all parent/guardians and  children, respectively, prior to inclusion in the study. Consent for publication:  Not Applicable. Competing interests: The authors declare no competing interests. Index. décimale : PER Périodiques Résumé : BACKGROUND: The Autonomic Nervous System (ANS) regulates 'automatic' functions such as heart rate, and alterations may have significant impacts on health outcomes. Cardiovascular measures of autonomic function such as heart rate variability are of interest as biological markers in autism spectrum disorder (ASD). The interplay between the ANS and physical health establishes a need to examine cardiovascular autonomic functioning in youth with and without ASD over development. The current study aimed to identify change in autonomic function and balance across the parasympathetic and sympathetic branches over time as a function of diagnosis, age, pubertal development, and physical health status. METHODS: The study included 244 ASD (N = 140) or neurotypical (NT) (N = 104) youth, ages 10 to 13 years at enrollment and followed over four years. Resting state autonomic functioning was measured using respiratory sinus arrhythmia (RSA; parasympathetic) and pre-ejection period (PEP; sympathetic). Autonomic balance and regulation were also examined as outcomes. Linear mixed models tested between- and within-group differences in the primary autonomic outcomes as well as the influence of pubertal development, body weight, and medication use. RESULTS: Baseline models showed diagnostic differences, with lower parasympathetic regulation, in youth with ASD, but no differences were observed for the other three outcomes. Adding body mass index (BMI) percentile and medication use removed the statistically significant diagnostic effect, while both variables were significantly related to lower RSA and overall autonomic regulation. Parasympathetic function (RSA) was stable over age and pubertal stage, while a notable decrease in sympathetic control (increased PEP) was found for age and pubertal stage. BMI percentile at enrollment significantly predicted autonomic function, while change in BMI over time did not. CONCLUSIONS: Minimal research to date has explored physical health (e.g., BMI) and autonomic outcomes in ASD. The current study observed few group differences yet demonstrates important effects of physical health on ANS function in both ASD and neurotypical youth. Findings further emphasize a need to focus on individual traits such as BMI and medication use to elucidate the extent to which autonomic differences are related to health status, irrespective of diagnostic category, across the lifespan. En ligne : https://dx.doi.org/10.1186/s11689-025-09602-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=576 [article] Pubertal developmental, body mass index, and cardiovascular autonomic function in children and adolescents with and without autism spectrum disorder: a four-time point accelerated longitudinal study [texte imprimé] / Rachael A. MUSCATELLO, Auteur ; Meredith COLA, Auteur ; Simon VANDEKAR, Auteur ; Blythe A. CORBETT, Auteur. Langues : Anglais (eng) in Journal of Neurodevelopmental Disorders > 17 (2025) Mots-clés : Humans  Adolescent  Child  Male  Female  Autism Spectrum Disorder/physiopathology  Longitudinal Studies  Body Mass Index  Autonomic Nervous System/physiopathology  Puberty/physiology  Heart Rate/physiology  Respiratory Sinus Arrhythmia/physiology  Autism  Autonomic  Cardiovascular  Health  Heart rate  Physical  Pubertal development  Variability  out in accordance with the Code of Ethics of the World Medical Association  (Declaration of Helsinki). The Vanderbilt Institutional Review Board approved all  study procedures. In compliance with the Institutional Review Board, informed  written consent and verbal assent was obtained from all parent/guardians and  children, respectively, prior to inclusion in the study. Consent for publication:  Not Applicable. Competing interests: The authors declare no competing interests. Index. décimale : PER Périodiques Résumé : BACKGROUND: The Autonomic Nervous System (ANS) regulates 'automatic' functions such as heart rate, and alterations may have significant impacts on health outcomes. Cardiovascular measures of autonomic function such as heart rate variability are of interest as biological markers in autism spectrum disorder (ASD). The interplay between the ANS and physical health establishes a need to examine cardiovascular autonomic functioning in youth with and without ASD over development. The current study aimed to identify change in autonomic function and balance across the parasympathetic and sympathetic branches over time as a function of diagnosis, age, pubertal development, and physical health status. METHODS: The study included 244 ASD (N = 140) or neurotypical (NT) (N = 104) youth, ages 10 to 13 years at enrollment and followed over four years. Resting state autonomic functioning was measured using respiratory sinus arrhythmia (RSA; parasympathetic) and pre-ejection period (PEP; sympathetic). Autonomic balance and regulation were also examined as outcomes. Linear mixed models tested between- and within-group differences in the primary autonomic outcomes as well as the influence of pubertal development, body weight, and medication use. RESULTS: Baseline models showed diagnostic differences, with lower parasympathetic regulation, in youth with ASD, but no differences were observed for the other three outcomes. Adding body mass index (BMI) percentile and medication use removed the statistically significant diagnostic effect, while both variables were significantly related to lower RSA and overall autonomic regulation. Parasympathetic function (RSA) was stable over age and pubertal stage, while a notable decrease in sympathetic control (increased PEP) was found for age and pubertal stage. BMI percentile at enrollment significantly predicted autonomic function, while change in BMI over time did not. CONCLUSIONS: Minimal research to date has explored physical health (e.g., BMI) and autonomic outcomes in ASD. The current study observed few group differences yet demonstrates important effects of physical health on ANS function in both ASD and neurotypical youth. Findings further emphasize a need to focus on individual traits such as BMI and medication use to elucidate the extent to which autonomic differences are related to health status, irrespective of diagnostic category, across the lifespan. En ligne : https://dx.doi.org/10.1186/s11689-025-09602-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=576

Sex-specific metrics for success: Gaps in social word use are bigger for autistic girls than boys / Meredith COLA in Autism, 30-6 (June 2026)  

Public ISBD [article]  inAutism > 30-6 (June 2026) . - p.1608-1614 Titre : Sex-specific metrics for success: Gaps in social word use are bigger for autistic girls than boys Type de document : texte imprimé Auteurs : Meredith COLA, Auteur ; Sarah SCHILLINGER, Auteur ; Margaret LYONS, Auteur ; Amanda LEE, Auteur ; Calliana FAULK, Auteur ; Maxine COVELLO, Auteur ; Nasya HOWARD, Auteur ; Hannah FRANKE, Auteur ; Alexandria MULQUEEN, Auteur ; Lizzy FULOP, Auteur ; Azia KNOX, Auteur ; Sunghye CHO, Auteur ; Mark Y. LIBERMAN, Auteur ; Juhi PANDEY, Auteur ; Ashlee YATES FLANAGAN, Auteur ; Joseph DONAHER, Auteur ; Robert T. SCHULTZ, Auteur ; Julia PARISH-MORRIS, Auteur Article en page(s) : p.1608-1614 Langues : Anglais (eng) Mots-clés : autism  communication and language  sex differences  social communication  social phenotype Index. décimale : PER Périodiques Résumé : Autistic girls are often diagnosed late, missed, or misdiagnosed, which can negatively impact quality of life and mental health. Although research shows the social profiles of autistic girls differ from boys in systematic ways that might explain gaps in diagnosis, little is known about how autistic girls’ social language compares to their same-sex non-autistic peers. This study investigated social words—words that make reference to other people—produced by 138 age- and IQ-matched autistic and non-autistic youth (ages 6–15) during one Autism Diagnostic Observation Schedule, Second Edition task. Girls used significantly more social words than boys across both diagnostic groups. There was a larger gap in social word production between autistic girls and non-autistic girls than autistic boys and non-autistic boys, with non-autistic girls using the most social words. Non-autistic girls’ social language behavior—including their social word production—sets an especially high bar for autistic girls, who often report trying to blend in with other girls. Growing evidence of the distinct social language profiles of autistic and non-autistic girls versus boys should guide researchers and clinicians to assess autism in ways that are sensitive to sex-associated differences and develop interventions that consider the norms of youth’s target social circles.Lay Abstract Autism is often diagnosed later in girls and women as compared to boys and men. More research is needed to understand how autism presents differently in girls. This study investigates how autistic and non-autistic youth aged 6 to 15 years use social words (e.g. “friend,” “mom,” “help,” “talk”) during an interview about friends, relationships, and marriage as part of an autism diagnostic assessment. Overall, girls used more social words compared to boys and talked more about friends. Specifically, non-autistic girls used the most social words in comparison with other groups. Highly social language produced by non-autistic girls may make it especially hard for autistic girls to blend in with other girls and could lead them to engage in more camouflaging behaviors to hide their autistic characteristics. With such different average social language behavior from girls and boys, researchers should consider adapting autism assessments and interventions to support the unique needs of autistic girls. En ligne : https://dx.doi.org/10.1177/13623613261417535 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=586 [article] Sex-specific metrics for success: Gaps in social word use are bigger for autistic girls than boys [texte imprimé] / Meredith COLA, Auteur ; Sarah SCHILLINGER, Auteur ; Margaret LYONS, Auteur ; Amanda LEE, Auteur ; Calliana FAULK, Auteur ; Maxine COVELLO, Auteur ; Nasya HOWARD, Auteur ; Hannah FRANKE, Auteur ; Alexandria MULQUEEN, Auteur ; Lizzy FULOP, Auteur ; Azia KNOX, Auteur ; Sunghye CHO, Auteur ; Mark Y. LIBERMAN, Auteur ; Juhi PANDEY, Auteur ; Ashlee YATES FLANAGAN, Auteur ; Joseph DONAHER, Auteur ; Robert T. SCHULTZ, Auteur ; Julia PARISH-MORRIS, Auteur . - p.1608-1614. Langues : Anglais (eng) in Autism > 30-6 (June 2026) . - p.1608-1614 Mots-clés : autism  communication and language  sex differences  social communication  social phenotype Index. décimale : PER Périodiques Résumé : Autistic girls are often diagnosed late, missed, or misdiagnosed, which can negatively impact quality of life and mental health. Although research shows the social profiles of autistic girls differ from boys in systematic ways that might explain gaps in diagnosis, little is known about how autistic girls’ social language compares to their same-sex non-autistic peers. This study investigated social words—words that make reference to other people—produced by 138 age- and IQ-matched autistic and non-autistic youth (ages 6–15) during one Autism Diagnostic Observation Schedule, Second Edition task. Girls used significantly more social words than boys across both diagnostic groups. There was a larger gap in social word production between autistic girls and non-autistic girls than autistic boys and non-autistic boys, with non-autistic girls using the most social words. Non-autistic girls’ social language behavior—including their social word production—sets an especially high bar for autistic girls, who often report trying to blend in with other girls. Growing evidence of the distinct social language profiles of autistic and non-autistic girls versus boys should guide researchers and clinicians to assess autism in ways that are sensitive to sex-associated differences and develop interventions that consider the norms of youth’s target social circles.Lay Abstract Autism is often diagnosed later in girls and women as compared to boys and men. More research is needed to understand how autism presents differently in girls. This study investigates how autistic and non-autistic youth aged 6 to 15 years use social words (e.g. “friend,” “mom,” “help,” “talk”) during an interview about friends, relationships, and marriage as part of an autism diagnostic assessment. Overall, girls used more social words compared to boys and talked more about friends. Specifically, non-autistic girls used the most social words in comparison with other groups. Highly social language produced by non-autistic girls may make it especially hard for autistic girls to blend in with other girls and could lead them to engage in more camouflaging behaviors to hide their autistic characteristics. With such different average social language behavior from girls and boys, researchers should consider adapting autism assessments and interventions to support the unique needs of autistic girls. En ligne : https://dx.doi.org/10.1177/13623613261417535 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=586

Short report: Autistic adults’ perceptions of gender, autism, and policing in the United States / Meredith COLA in Autism, 30-5 (May 2026)  

Public ISBD [article]  inAutism > 30-5 (May 2026) . - p.1368-1377 Titre : Short report: Autistic adults’ perceptions of gender, autism, and policing in the United States Type de document : texte imprimé Auteurs : Meredith COLA, Auteur ; Aili HAUPTMANN, Auteur ; Alison RUSSELL, Auteur ; Dieu M. TRUONG, Auteur ; Ashlee YATES FLANAGAN, Auteur ; Kimberly G. TENA, Auteur ; Juan PACHECO, Auteur ; Ashley ZITTER, Auteur ; Azia KNOX, Auteur ; Maggie Rose PELELLA, Auteur ; Lizzy FULOP, Auteur ; Maxine COVELLO, Auteur ; Amanda LEE, Auteur ; Margaret LYONS, Auteur ; Sarah SCHILLINGER, Auteur ; Rita SOLORZANO, Auteur ; Sinan TURNACIOGLU, Auteur ; Vijay RAVINDRAN, Auteur ; Judith S. MILLER, Auteur ; Joseph P. MCCLEERY, Auteur ; Julia PARISH-MORRIS, Auteur Article en page(s) : p.1368-1377 Langues : Anglais (eng) Mots-clés : autism  gender diversity  law enforcement  police  policy Index. décimale : PER Périodiques Résumé : Autistic individuals face increased risk during police interactions in the United States, including injury and death. Research shows police behave inequitably during interactions with marginalized communities and may behave even more inequitably toward individuals with multiple minoritized identities. Many autistic people also identify as gender diverse. However, it is largely unknown if or how autistic adults’ perceptions of police differ by gender identity. We examined autistic adults’ perceptions of policing, autism, and gender using an online questionnaire. Results revealed significant differences across gender groups (cis women, cis men, gender diverse) in perceptions of justice, comfort in disclosing diagnosis, helpfulness of diagnostic disclosure, influence of gender, and concern that one’s autistic traits would be misperceived as dangerous. These findings align with widespread calls for police reform and suggest current policing practices likely do not meet the needs of all autistic individuals, particularly autistic cis women and gender diverse individuals, who are more likely to report their gender has influenced police interactions and more concerned that their autistic characteristics are being misperceived, relative to autistic cis men. Reducing the harm marginalized groups face because of systemic inequities in the current policing system is a critical need that could enhance safety for autistic individuals.Lay abstract Autistic people in the United States are at a higher risk of injury or death when they interact with the police. Research has shown that police often treat people from minoritized communities unfairly, and this can be even worse for people who belong to more than one minoritized group, like being both autistic and gender diverse. Many autistic people also identify as gender diverse. However, we do not yet know if autistic people’s views of police may differ across gender identities. In this study, we explored how autistic adults view police and if those views differ across different gender identities. We found that autistic adults with different gender identities have different views on things like justice, how comfortable they feel telling police about their autism diagnosis, whether they think telling the police about their diagnosis would be helpful, how they think their gender affects police behavior, and whether they worry that their autistic traits might be seen as dangerous. These results may indicate that the current policing practices may not take into account autistic individuals’ unique perspectives and experiences, particularly when police are interacting with autistic women and gender diverse people. It is important that we make changes to reduce the harm that autistic people face because of unfairness in the current policing system using feedback from autistic individuals. This could make things safer for all autistic people. Our results suggest it could be beneficial for police officers to receive training that is inclusive of the gender diversity within the autistic community, so they can better protect and respect all autistic people. En ligne : https://dx.doi.org/10.1177/13623613251395539 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=585 [article] Short report: Autistic adults’ perceptions of gender, autism, and policing in the United States [texte imprimé] / Meredith COLA, Auteur ; Aili HAUPTMANN, Auteur ; Alison RUSSELL, Auteur ; Dieu M. TRUONG, Auteur ; Ashlee YATES FLANAGAN, Auteur ; Kimberly G. TENA, Auteur ; Juan PACHECO, Auteur ; Ashley ZITTER, Auteur ; Azia KNOX, Auteur ; Maggie Rose PELELLA, Auteur ; Lizzy FULOP, Auteur ; Maxine COVELLO, Auteur ; Amanda LEE, Auteur ; Margaret LYONS, Auteur ; Sarah SCHILLINGER, Auteur ; Rita SOLORZANO, Auteur ; Sinan TURNACIOGLU, Auteur ; Vijay RAVINDRAN, Auteur ; Judith S. MILLER, Auteur ; Joseph P. MCCLEERY, Auteur ; Julia PARISH-MORRIS, Auteur . - p.1368-1377. Langues : Anglais (eng) in Autism > 30-5 (May 2026) . - p.1368-1377 Mots-clés : autism  gender diversity  law enforcement  police  policy Index. décimale : PER Périodiques Résumé : Autistic individuals face increased risk during police interactions in the United States, including injury and death. Research shows police behave inequitably during interactions with marginalized communities and may behave even more inequitably toward individuals with multiple minoritized identities. Many autistic people also identify as gender diverse. However, it is largely unknown if or how autistic adults’ perceptions of police differ by gender identity. We examined autistic adults’ perceptions of policing, autism, and gender using an online questionnaire. Results revealed significant differences across gender groups (cis women, cis men, gender diverse) in perceptions of justice, comfort in disclosing diagnosis, helpfulness of diagnostic disclosure, influence of gender, and concern that one’s autistic traits would be misperceived as dangerous. These findings align with widespread calls for police reform and suggest current policing practices likely do not meet the needs of all autistic individuals, particularly autistic cis women and gender diverse individuals, who are more likely to report their gender has influenced police interactions and more concerned that their autistic characteristics are being misperceived, relative to autistic cis men. Reducing the harm marginalized groups face because of systemic inequities in the current policing system is a critical need that could enhance safety for autistic individuals.Lay abstract Autistic people in the United States are at a higher risk of injury or death when they interact with the police. Research has shown that police often treat people from minoritized communities unfairly, and this can be even worse for people who belong to more than one minoritized group, like being both autistic and gender diverse. Many autistic people also identify as gender diverse. However, we do not yet know if autistic people’s views of police may differ across gender identities. In this study, we explored how autistic adults view police and if those views differ across different gender identities. We found that autistic adults with different gender identities have different views on things like justice, how comfortable they feel telling police about their autism diagnosis, whether they think telling the police about their diagnosis would be helpful, how they think their gender affects police behavior, and whether they worry that their autistic traits might be seen as dangerous. These results may indicate that the current policing practices may not take into account autistic individuals’ unique perspectives and experiences, particularly when police are interacting with autistic women and gender diverse people. It is important that we make changes to reduce the harm that autistic people face because of unfairness in the current policing system using feedback from autistic individuals. This could make things safer for all autistic people. Our results suggest it could be beneficial for police officers to receive training that is inclusive of the gender diversity within the autistic community, so they can better protect and respect all autistic people. En ligne : https://dx.doi.org/10.1177/13623613251395539 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=585

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