Autism Spectrum Disorder: Does Neuroimaging Support the DSM-5 Proposal for a Symptom Dyad? A Systematic Review of Functional Magnetic Resonance Imaging and Diffusion Tensor Imaging Studies / Laura PINA-CAMACHO in Journal of Autism and Developmental Disorders, 42-7 (July 2012)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 42-7 (July 2012) . - p.1326-1341 Titre : Autism Spectrum Disorder: Does Neuroimaging Support the DSM-5 Proposal for a Symptom Dyad? A Systematic Review of Functional Magnetic Resonance Imaging and Diffusion Tensor Imaging Studies Type de document : Texte imprimé et/ou numérique Auteurs : Laura PINA-CAMACHO, Auteur ; Sonia VILLERO, Auteur ; David FRAGUAS, Auteur ; Leticia BOADA, Auteur ; Joost JANSSEN, Auteur ; Francisco J. NAVAS-SANCHEZ, Auteur ; María MAYORAL, Auteur ; Cloe LLORENTE, Auteur ; Celso ARANGO, Auteur ; Mara PARELLADA, Auteur Année de publication : 2012 Article en page(s) : p.1326-1341 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Autistic disorder  Asperger syndrome  Functional magnetic resonance imaging  Diffusion tensor imaging Index. décimale : PER Périodiques Résumé : A systematic review of 208 studies comprising functional magnetic resonance imaging and diffusion tensor imaging data in patients with ‘autism spectrum disorder’ (ASD) was conducted, in order to determine whether these data support the forthcoming DSM-5 proposal of a social communication and behavioral symptom dyad. Studies consistently reported abnormal function and structure of fronto-temporal and limbic networks with social and pragmatic language deficits, of temporo-parieto-occipital networks with syntactic–semantic language deficits, and of fronto-striato-cerebellar networks with repetitive behaviors and restricted interests in ASD patients. Therefore, this review partially supports the DSM-5 proposal for the ASD dyad. En ligne : http://dx.doi.org/10.1007/s10803-011-1360-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=166 [article] Autism Spectrum Disorder: Does Neuroimaging Support the DSM-5 Proposal for a Symptom Dyad? A Systematic Review of Functional Magnetic Resonance Imaging and Diffusion Tensor Imaging Studies [Texte imprimé et/ou numérique] / Laura PINA-CAMACHO, Auteur ; Sonia VILLERO, Auteur ; David FRAGUAS, Auteur ; Leticia BOADA, Auteur ; Joost JANSSEN, Auteur ; Francisco J. NAVAS-SANCHEZ, Auteur ; María MAYORAL, Auteur ; Cloe LLORENTE, Auteur ; Celso ARANGO, Auteur ; Mara PARELLADA, Auteur . - 2012 . - p.1326-1341. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 42-7 (July 2012) . - p.1326-1341 Mots-clés : Autism spectrum disorder  Autistic disorder  Asperger syndrome  Functional magnetic resonance imaging  Diffusion tensor imaging Index. décimale : PER Périodiques Résumé : A systematic review of 208 studies comprising functional magnetic resonance imaging and diffusion tensor imaging data in patients with ‘autism spectrum disorder’ (ASD) was conducted, in order to determine whether these data support the forthcoming DSM-5 proposal of a social communication and behavioral symptom dyad. Studies consistently reported abnormal function and structure of fronto-temporal and limbic networks with social and pragmatic language deficits, of temporo-parieto-occipital networks with syntactic–semantic language deficits, and of fronto-striato-cerebellar networks with repetitive behaviors and restricted interests in ASD patients. Therefore, this review partially supports the DSM-5 proposal for the ASD dyad. En ligne : http://dx.doi.org/10.1007/s10803-011-1360-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=166

Estimation of the Intelligence Quotient Using Wechsler Intelligence Scales in Children and Adolescents with Asperger Syndrome / Jessica MERCHAN-NARANJO in Journal of Autism and Developmental Disorders, 42-1 (January 2012)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 42-1 (January 2012) . - p.116-122 Titre : Estimation of the Intelligence Quotient Using Wechsler Intelligence Scales in Children and Adolescents with Asperger Syndrome Type de document : Texte imprimé et/ou numérique Auteurs : Jessica MERCHAN-NARANJO, Auteur ; María MAYORAL, Auteur ; Marta RAPADO-CASTRO, Auteur ; Cloe LLORENTE, Auteur ; Leticia BOADA, Auteur ; Celso ARANGO, Auteur ; Mara PARELLADA, Auteur Année de publication : 2012 Article en page(s) : p.116-122 Langues : Anglais (eng) Mots-clés : Asperger syndrome  Intelligence  Cognitive profile  Wechsler Scales  Short forms  Dyads Index. décimale : PER Périodiques Résumé : Asperger syndrome (AS) patients show heterogeneous intelligence profiles and the validity of short forms for estimating intelligence has rarely been studied in this population. We analyzed the validity of Wechsler Intelligence Scale (WIS) short forms for estimating full-scale intelligence quotient (FSIQ) and assessing intelligence profiles in 29 AS patients. Only the Information and Block Design dyad meets the study criteria. No statistically significant differences were found between dyad scores and FSIQ scores ( t (28) = 1.757; p = 0.09). The dyad has a high correlation with FSIQ, good percentage of variance explained ( R 2 = 0.591; p < 0.001), and high consistency with the FSIQ classification ( χ 2 (36) = 45.202; p = 0.14). Short forms with good predictive accuracy may not be accurate in clinical groups with atypical cognitive profiles such as AS patients. En ligne : http://dx.doi.org/10.1007/s10803-011-1219-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=151 [article] Estimation of the Intelligence Quotient Using Wechsler Intelligence Scales in Children and Adolescents with Asperger Syndrome [Texte imprimé et/ou numérique] / Jessica MERCHAN-NARANJO, Auteur ; María MAYORAL, Auteur ; Marta RAPADO-CASTRO, Auteur ; Cloe LLORENTE, Auteur ; Leticia BOADA, Auteur ; Celso ARANGO, Auteur ; Mara PARELLADA, Auteur . - 2012 . - p.116-122. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 42-1 (January 2012) . - p.116-122 Mots-clés : Asperger syndrome  Intelligence  Cognitive profile  Wechsler Scales  Short forms  Dyads Index. décimale : PER Périodiques Résumé : Asperger syndrome (AS) patients show heterogeneous intelligence profiles and the validity of short forms for estimating intelligence has rarely been studied in this population. We analyzed the validity of Wechsler Intelligence Scale (WIS) short forms for estimating full-scale intelligence quotient (FSIQ) and assessing intelligence profiles in 29 AS patients. Only the Information and Block Design dyad meets the study criteria. No statistically significant differences were found between dyad scores and FSIQ scores ( t (28) = 1.757; p = 0.09). The dyad has a high correlation with FSIQ, good percentage of variance explained ( R 2 = 0.591; p < 0.001), and high consistency with the FSIQ classification ( χ 2 (36) = 45.202; p = 0.14). Short forms with good predictive accuracy may not be accurate in clinical groups with atypical cognitive profiles such as AS patients. En ligne : http://dx.doi.org/10.1007/s10803-011-1219-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=151

Longitudinal study of neurological soft signs in first-episode early-onset psychosis / María MAYORAL in Journal of Child Psychology and Psychiatry, 53-3 (March 2012)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 53-3 (March 2012) . - p.323-331 Titre : Longitudinal study of neurological soft signs in first-episode early-onset psychosis Type de document : Texte imprimé et/ou numérique Auteurs : María MAYORAL, Auteur ; I. BOMBIN, Auteur ; Josefina CASTRO-FORNIELES, Auteur ; Ana GONZALEZ-PINTO, Auteur ; Soraya OTERO, Auteur ; Mara PARELLADA, Auteur ; Dolores MORENO, Auteur ; I. BAEZA, Auteur ; Montserrat GRAELL, Auteur ; Marta RAPADO, Auteur ; Celso ARANGO, Auteur Année de publication : 2012 Article en page(s) : p.323-331 Langues : Anglais (eng) Mots-clés : Neurological soft signs  children and adolescents  psychosis  neurodevelopment Index. décimale : PER Périodiques Résumé : Background:  In recent decades, the assessment of neurological soft signs (NSS) in patients with psychosis has become a subject of special interest. The study of the progression of NSS during adolescence will provide valuable information about the role of NSS as endophenotypes or biomarkers and about brain development at a stage in which brain maturation has not yet been completed. Methods:  Neurological soft signs were assessed in a sample of 110 first episodes of early-onset psychosis (EOP) and 98 healthy children and adolescents at two different times in a 2-year follow-up period. Results:  Patients with EOP showed more NSS than controls both at baseline (p < .001) and the 2-year follow-up (p < .001). No differences were found in the number of signs among the different diagnostic subgroups (schizophrenia, bipolar disorder, and other psychoses). When we examined the changes in NSS over the follow-up, the reduction of NSS in the patients was greater than the controls for ‘Motor coordination’ (p = .032), ‘Others’ (p < .001), and ‘Total score’ (p < .001) of the NES. Conclusion:  Despite the greater reduction of NSS in patients than in controls along the follow-up, patients still have more neurological signs than healthy controls; therefore, these signs may be considered a trait marker. NSS do not seem to be specific to schizophrenia as they are present in different EOPs. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02475.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=152 [article] Longitudinal study of neurological soft signs in first-episode early-onset psychosis [Texte imprimé et/ou numérique] / María MAYORAL, Auteur ; I. BOMBIN, Auteur ; Josefina CASTRO-FORNIELES, Auteur ; Ana GONZALEZ-PINTO, Auteur ; Soraya OTERO, Auteur ; Mara PARELLADA, Auteur ; Dolores MORENO, Auteur ; I. BAEZA, Auteur ; Montserrat GRAELL, Auteur ; Marta RAPADO, Auteur ; Celso ARANGO, Auteur . - 2012 . - p.323-331. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 53-3 (March 2012) . - p.323-331 Mots-clés : Neurological soft signs  children and adolescents  psychosis  neurodevelopment Index. décimale : PER Périodiques Résumé : Background:  In recent decades, the assessment of neurological soft signs (NSS) in patients with psychosis has become a subject of special interest. The study of the progression of NSS during adolescence will provide valuable information about the role of NSS as endophenotypes or biomarkers and about brain development at a stage in which brain maturation has not yet been completed. Methods:  Neurological soft signs were assessed in a sample of 110 first episodes of early-onset psychosis (EOP) and 98 healthy children and adolescents at two different times in a 2-year follow-up period. Results:  Patients with EOP showed more NSS than controls both at baseline (p < .001) and the 2-year follow-up (p < .001). No differences were found in the number of signs among the different diagnostic subgroups (schizophrenia, bipolar disorder, and other psychoses). When we examined the changes in NSS over the follow-up, the reduction of NSS in the patients was greater than the controls for ‘Motor coordination’ (p = .032), ‘Others’ (p < .001), and ‘Total score’ (p < .001) of the NES. Conclusion:  Despite the greater reduction of NSS in patients than in controls along the follow-up, patients still have more neurological signs than healthy controls; therefore, these signs may be considered a trait marker. NSS do not seem to be specific to schizophrenia as they are present in different EOPs. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02475.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=152

Structural magnetic resonance imaging data do not help support DSM-5 autism spectrum disorder category / Laura PINA-CAMACHO in Research in Autism Spectrum Disorders, 7-2 (February 2013)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 7-2 (February 2013) . - p.333-343 Titre : Structural magnetic resonance imaging data do not help support DSM-5 autism spectrum disorder category Type de document : Texte imprimé et/ou numérique Auteurs : Laura PINA-CAMACHO, Auteur ; Sonia VILLERO, Auteur ; Leticia BOADA, Auteur ; David FRAGUAS, Auteur ; Joost JANSSEN, Auteur ; María MAYORAL, Auteur ; Cloe LLORENTE, Auteur ; Celso ARANGO, Auteur ; Mara PARELLADA, Auteur Année de publication : 2013 Article en page(s) : p.333-343 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Autistic disorder  Asperger syndrome  Structural magnetic resonance imaging  DSM-5 Index. décimale : PER Périodiques Résumé : This systematic review aims to determine whether or not structural magnetic resonance imaging (sMRI) data support the DSM-5 proposal of an autism spectrum disorder (ASD) diagnostic category, and whether or not classical DSM-IV autistic disorder (AD) and Asperger syndrome (AS) categories should be subsumed into it. The most replicated sMRI findings in patients with ASD compared with healthy controls are increased total brain volume in early childhood and decreased corpus callosum volume. Regarding the notion of a spectrum, some studies support that AS and AD are similar but 'quantitatively different' diagnostic categories, whereas others support that they are 'qualitatively different' entities with specific brain structural abnormalities. It seems that there are still not enough arguments from sMRI data for or against subsuming DSM-IV categories under a single ASD category. En ligne : http://dx.doi.org/10.1016/j.rasd.2012.08.013 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=186 [article] Structural magnetic resonance imaging data do not help support DSM-5 autism spectrum disorder category [Texte imprimé et/ou numérique] / Laura PINA-CAMACHO, Auteur ; Sonia VILLERO, Auteur ; Leticia BOADA, Auteur ; David FRAGUAS, Auteur ; Joost JANSSEN, Auteur ; María MAYORAL, Auteur ; Cloe LLORENTE, Auteur ; Celso ARANGO, Auteur ; Mara PARELLADA, Auteur . - 2013 . - p.333-343. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 7-2 (February 2013) . - p.333-343 Mots-clés : Autism spectrum disorder  Autistic disorder  Asperger syndrome  Structural magnetic resonance imaging  DSM-5 Index. décimale : PER Périodiques Résumé : This systematic review aims to determine whether or not structural magnetic resonance imaging (sMRI) data support the DSM-5 proposal of an autism spectrum disorder (ASD) diagnostic category, and whether or not classical DSM-IV autistic disorder (AD) and Asperger syndrome (AS) categories should be subsumed into it. The most replicated sMRI findings in patients with ASD compared with healthy controls are increased total brain volume in early childhood and decreased corpus callosum volume. Regarding the notion of a spectrum, some studies support that AS and AD are similar but 'quantitatively different' diagnostic categories, whereas others support that they are 'qualitatively different' entities with specific brain structural abnormalities. It seems that there are still not enough arguments from sMRI data for or against subsuming DSM-IV categories under a single ASD category. En ligne : http://dx.doi.org/10.1016/j.rasd.2012.08.013 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=186

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