Autism Spectrum Disorder: Does Neuroimaging Support the DSM-5 Proposal for a Symptom Dyad? A Systematic Review of Functional Magnetic Resonance Imaging and Diffusion Tensor Imaging Studies / Laura PINA-CAMACHO in Journal of Autism and Developmental Disorders, 42-7 (July 2012)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 42-7 (July 2012) . - p.1326-1341 Titre : Autism Spectrum Disorder: Does Neuroimaging Support the DSM-5 Proposal for a Symptom Dyad? A Systematic Review of Functional Magnetic Resonance Imaging and Diffusion Tensor Imaging Studies Type de document : Texte imprimé et/ou numérique Auteurs : Laura PINA-CAMACHO, Auteur ; Sonia VILLERO, Auteur ; David FRAGUAS, Auteur ; Leticia BOADA, Auteur ; Joost JANSSEN, Auteur ; Francisco J. NAVAS-SANCHEZ, Auteur ; María MAYORAL, Auteur ; Cloe LLORENTE, Auteur ; Celso ARANGO, Auteur ; Mara PARELLADA, Auteur Année de publication : 2012 Article en page(s) : p.1326-1341 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Autistic disorder  Asperger syndrome  Functional magnetic resonance imaging  Diffusion tensor imaging Index. décimale : PER Périodiques Résumé : A systematic review of 208 studies comprising functional magnetic resonance imaging and diffusion tensor imaging data in patients with ‘autism spectrum disorder’ (ASD) was conducted, in order to determine whether these data support the forthcoming DSM-5 proposal of a social communication and behavioral symptom dyad. Studies consistently reported abnormal function and structure of fronto-temporal and limbic networks with social and pragmatic language deficits, of temporo-parieto-occipital networks with syntactic–semantic language deficits, and of fronto-striato-cerebellar networks with repetitive behaviors and restricted interests in ASD patients. Therefore, this review partially supports the DSM-5 proposal for the ASD dyad. En ligne : http://dx.doi.org/10.1007/s10803-011-1360-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=166 [article] Autism Spectrum Disorder: Does Neuroimaging Support the DSM-5 Proposal for a Symptom Dyad? A Systematic Review of Functional Magnetic Resonance Imaging and Diffusion Tensor Imaging Studies [Texte imprimé et/ou numérique] / Laura PINA-CAMACHO, Auteur ; Sonia VILLERO, Auteur ; David FRAGUAS, Auteur ; Leticia BOADA, Auteur ; Joost JANSSEN, Auteur ; Francisco J. NAVAS-SANCHEZ, Auteur ; María MAYORAL, Auteur ; Cloe LLORENTE, Auteur ; Celso ARANGO, Auteur ; Mara PARELLADA, Auteur . - 2012 . - p.1326-1341. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 42-7 (July 2012) . - p.1326-1341 Mots-clés : Autism spectrum disorder  Autistic disorder  Asperger syndrome  Functional magnetic resonance imaging  Diffusion tensor imaging Index. décimale : PER Périodiques Résumé : A systematic review of 208 studies comprising functional magnetic resonance imaging and diffusion tensor imaging data in patients with ‘autism spectrum disorder’ (ASD) was conducted, in order to determine whether these data support the forthcoming DSM-5 proposal of a social communication and behavioral symptom dyad. Studies consistently reported abnormal function and structure of fronto-temporal and limbic networks with social and pragmatic language deficits, of temporo-parieto-occipital networks with syntactic–semantic language deficits, and of fronto-striato-cerebellar networks with repetitive behaviors and restricted interests in ASD patients. Therefore, this review partially supports the DSM-5 proposal for the ASD dyad. En ligne : http://dx.doi.org/10.1007/s10803-011-1360-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=166

Estimation of the Intelligence Quotient Using Wechsler Intelligence Scales in Children and Adolescents with Asperger Syndrome / Jessica MERCHAN-NARANJO in Journal of Autism and Developmental Disorders, 42-1 (January 2012)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 42-1 (January 2012) . - p.116-122 Titre : Estimation of the Intelligence Quotient Using Wechsler Intelligence Scales in Children and Adolescents with Asperger Syndrome Type de document : Texte imprimé et/ou numérique Auteurs : Jessica MERCHAN-NARANJO, Auteur ; María MAYORAL, Auteur ; Marta RAPADO-CASTRO, Auteur ; Cloe LLORENTE, Auteur ; Leticia BOADA, Auteur ; Celso ARANGO, Auteur ; Mara PARELLADA, Auteur Année de publication : 2012 Article en page(s) : p.116-122 Langues : Anglais (eng) Mots-clés : Asperger syndrome  Intelligence  Cognitive profile  Wechsler Scales  Short forms  Dyads Index. décimale : PER Périodiques Résumé : Asperger syndrome (AS) patients show heterogeneous intelligence profiles and the validity of short forms for estimating intelligence has rarely been studied in this population. We analyzed the validity of Wechsler Intelligence Scale (WIS) short forms for estimating full-scale intelligence quotient (FSIQ) and assessing intelligence profiles in 29 AS patients. Only the Information and Block Design dyad meets the study criteria. No statistically significant differences were found between dyad scores and FSIQ scores ( t (28) = 1.757; p = 0.09). The dyad has a high correlation with FSIQ, good percentage of variance explained ( R 2 = 0.591; p < 0.001), and high consistency with the FSIQ classification ( χ 2 (36) = 45.202; p = 0.14). Short forms with good predictive accuracy may not be accurate in clinical groups with atypical cognitive profiles such as AS patients. En ligne : http://dx.doi.org/10.1007/s10803-011-1219-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=151 [article] Estimation of the Intelligence Quotient Using Wechsler Intelligence Scales in Children and Adolescents with Asperger Syndrome [Texte imprimé et/ou numérique] / Jessica MERCHAN-NARANJO, Auteur ; María MAYORAL, Auteur ; Marta RAPADO-CASTRO, Auteur ; Cloe LLORENTE, Auteur ; Leticia BOADA, Auteur ; Celso ARANGO, Auteur ; Mara PARELLADA, Auteur . - 2012 . - p.116-122. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 42-1 (January 2012) . - p.116-122 Mots-clés : Asperger syndrome  Intelligence  Cognitive profile  Wechsler Scales  Short forms  Dyads Index. décimale : PER Périodiques Résumé : Asperger syndrome (AS) patients show heterogeneous intelligence profiles and the validity of short forms for estimating intelligence has rarely been studied in this population. We analyzed the validity of Wechsler Intelligence Scale (WIS) short forms for estimating full-scale intelligence quotient (FSIQ) and assessing intelligence profiles in 29 AS patients. Only the Information and Block Design dyad meets the study criteria. No statistically significant differences were found between dyad scores and FSIQ scores ( t (28) = 1.757; p = 0.09). The dyad has a high correlation with FSIQ, good percentage of variance explained ( R 2 = 0.591; p < 0.001), and high consistency with the FSIQ classification ( χ 2 (36) = 45.202; p = 0.14). Short forms with good predictive accuracy may not be accurate in clinical groups with atypical cognitive profiles such as AS patients. En ligne : http://dx.doi.org/10.1007/s10803-011-1219-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=151

Practitioner Review: Long-term pharmacological treatment of pediatric bipolar disorder / Covadonga M. DIAZ-CANEJA in Journal of Child Psychology and Psychiatry, 55-9 (September 2014)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 55-9 (September 2014) . - p.959-980 Titre : Practitioner Review: Long-term pharmacological treatment of pediatric bipolar disorder Type de document : Texte imprimé et/ou numérique Auteurs : Covadonga M. DIAZ-CANEJA, Auteur ; Carmen MORENO, Auteur ; Cloe LLORENTE, Auteur ; Ana ESPLIEGO, Auteur ; Celso ARANGO, Auteur ; Dolores MORENO, Auteur Article en page(s) : p.959-980 Langues : Anglais (eng) Mots-clés : Bipolar  mania  maintenance  mood stabilizer  antipsychotic  child  adolescent Index. décimale : PER Périodiques Résumé : Background Although long-term treatment is a core aspect of the management of children and adolescents with bipolar disorder (BD), most clinical recommendations are based on results from short-term studies or adult data. In order to guide clinical practice, we review the efficacy and safety profile of mood stabilizers, antipsychotics, and other pharmacological strategies for the long-term treatment of BD in pediatric patients. Methods A MEDLINE, EMBASE, Cochrane and PsycInfo search (inception through November 2013) was performed to identify prospective studies longer than 12 weeks assessing the use of pharmacological strategies for the long-term treatment of BD in pediatric patients (0–18 years of age). Results Four randomized controlled trials (RCT) [three placebo-controlled (assessing aripiprazole (2) and flax oil), and one head-to-head comparison of lithium vs. divalproex], and thirteen noncontrolled studies (six open-label studies assessing lithium or anticonvulsants, five assessing second-generation antipsychotics (SGAs) and four assessing combination strategies) were included in the review. Aripiprazole has shown efficacy for relapse prevention in children with pediatric bipolar disorder (PBD) 4–9 years of age in one placebo-controlled RCT. Positive results have been reported in noncontrolled studies with quetiapine and lithium for relapse prevention, as well as with lithium, quetiapine, ziprasidone, and the combination of risperidone and divalproex or lithium for long-term symptom reduction in PBD. The most frequently reported adverse events in children and adolescents treated with lithium and anticonvulsants are gastrointestinal and neurological, whereas use of SGAs is mainly related to weight gain and sedation. Conclusion According to the limited empirical evidence, aripiprazole can be useful for relapse prevention in children with PBD. Given the lack of consistent efficacy data, clinical decision making should be based on individual clinical aspects and safety concerns. En ligne : http://dx.doi.org/10.1111/jcpp.12271 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=238 [article] Practitioner Review: Long-term pharmacological treatment of pediatric bipolar disorder [Texte imprimé et/ou numérique] / Covadonga M. DIAZ-CANEJA, Auteur ; Carmen MORENO, Auteur ; Cloe LLORENTE, Auteur ; Ana ESPLIEGO, Auteur ; Celso ARANGO, Auteur ; Dolores MORENO, Auteur . - p.959-980. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 55-9 (September 2014) . - p.959-980 Mots-clés : Bipolar  mania  maintenance  mood stabilizer  antipsychotic  child  adolescent Index. décimale : PER Périodiques Résumé : Background Although long-term treatment is a core aspect of the management of children and adolescents with bipolar disorder (BD), most clinical recommendations are based on results from short-term studies or adult data. In order to guide clinical practice, we review the efficacy and safety profile of mood stabilizers, antipsychotics, and other pharmacological strategies for the long-term treatment of BD in pediatric patients. Methods A MEDLINE, EMBASE, Cochrane and PsycInfo search (inception through November 2013) was performed to identify prospective studies longer than 12 weeks assessing the use of pharmacological strategies for the long-term treatment of BD in pediatric patients (0–18 years of age). Results Four randomized controlled trials (RCT) [three placebo-controlled (assessing aripiprazole (2) and flax oil), and one head-to-head comparison of lithium vs. divalproex], and thirteen noncontrolled studies (six open-label studies assessing lithium or anticonvulsants, five assessing second-generation antipsychotics (SGAs) and four assessing combination strategies) were included in the review. Aripiprazole has shown efficacy for relapse prevention in children with pediatric bipolar disorder (PBD) 4–9 years of age in one placebo-controlled RCT. Positive results have been reported in noncontrolled studies with quetiapine and lithium for relapse prevention, as well as with lithium, quetiapine, ziprasidone, and the combination of risperidone and divalproex or lithium for long-term symptom reduction in PBD. The most frequently reported adverse events in children and adolescents treated with lithium and anticonvulsants are gastrointestinal and neurological, whereas use of SGAs is mainly related to weight gain and sedation. Conclusion According to the limited empirical evidence, aripiprazole can be useful for relapse prevention in children with PBD. Given the lack of consistent efficacy data, clinical decision making should be based on individual clinical aspects and safety concerns. En ligne : http://dx.doi.org/10.1111/jcpp.12271 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=238

Psychopathology in Children and Adolescents with ASD Without Mental Retardation / Marta CAAMANO in Journal of Autism and Developmental Disorders, 43-10 (October 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2442-2449 Titre : Psychopathology in Children and Adolescents with ASD Without Mental Retardation Type de document : Texte imprimé et/ou numérique Auteurs : Marta CAAMANO, Auteur ; Leticia BOADA, Auteur ; Jessica MERCHAN-NARANJO, Auteur ; Carmen MORENO, Auteur ; Cloe LLORENTE, Auteur ; Dolores MORENO, Auteur ; Celso ARANGO, Auteur ; Mara PARELLADA, Auteur Article en page(s) : p.2442-2449 Langues : Anglais (eng) Mots-clés : Asperger syndrome  Psychopathology  Comorbidity  Adolescent  Developmental disorders Index. décimale : PER Périodiques Résumé : This study analyzes subclinical psychopathology in children and adolescents with autism spectrum disorders (ASD) without mental retardation with no comorbid disorder, assessed by an extensive general psychopathology interview. The K-SADS-PL was administered to a group of 25 patients with ASD (mean age = 12.80 ± 2.86 years) and 25 healthy controls (mean age 12.52 ± 2.86 years). Significant differences were found between patients with ASD and controls for the domains of: depressive disorder, anxiety separation disorder, agoraphobia and specific phobias, obsessive compulsive disorder (OCD), and attention deficit hyperactivity disorder (ADHD). In patients without a comorbid disorder, we found a profile of subclinical disturbances that suggest high risk for comorbid psychiatric conditions derived from the presence of subthreshold symptomatology. En ligne : http://dx.doi.org/10.1007/s10803-013-1792-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215 [article] Psychopathology in Children and Adolescents with ASD Without Mental Retardation [Texte imprimé et/ou numérique] / Marta CAAMANO, Auteur ; Leticia BOADA, Auteur ; Jessica MERCHAN-NARANJO, Auteur ; Carmen MORENO, Auteur ; Cloe LLORENTE, Auteur ; Dolores MORENO, Auteur ; Celso ARANGO, Auteur ; Mara PARELLADA, Auteur . - p.2442-2449. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-10 (October 2013) . - p.2442-2449 Mots-clés : Asperger syndrome  Psychopathology  Comorbidity  Adolescent  Developmental disorders Index. décimale : PER Périodiques Résumé : This study analyzes subclinical psychopathology in children and adolescents with autism spectrum disorders (ASD) without mental retardation with no comorbid disorder, assessed by an extensive general psychopathology interview. The K-SADS-PL was administered to a group of 25 patients with ASD (mean age = 12.80 ± 2.86 years) and 25 healthy controls (mean age 12.52 ± 2.86 years). Significant differences were found between patients with ASD and controls for the domains of: depressive disorder, anxiety separation disorder, agoraphobia and specific phobias, obsessive compulsive disorder (OCD), and attention deficit hyperactivity disorder (ADHD). In patients without a comorbid disorder, we found a profile of subclinical disturbances that suggest high risk for comorbid psychiatric conditions derived from the presence of subthreshold symptomatology. En ligne : http://dx.doi.org/10.1007/s10803-013-1792-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=215

Structural magnetic resonance imaging data do not help support DSM-5 autism spectrum disorder category / Laura PINA-CAMACHO in Research in Autism Spectrum Disorders, 7-2 (February 2013)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 7-2 (February 2013) . - p.333-343 Titre : Structural magnetic resonance imaging data do not help support DSM-5 autism spectrum disorder category Type de document : Texte imprimé et/ou numérique Auteurs : Laura PINA-CAMACHO, Auteur ; Sonia VILLERO, Auteur ; Leticia BOADA, Auteur ; David FRAGUAS, Auteur ; Joost JANSSEN, Auteur ; María MAYORAL, Auteur ; Cloe LLORENTE, Auteur ; Celso ARANGO, Auteur ; Mara PARELLADA, Auteur Année de publication : 2013 Article en page(s) : p.333-343 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Autistic disorder  Asperger syndrome  Structural magnetic resonance imaging  DSM-5 Index. décimale : PER Périodiques Résumé : This systematic review aims to determine whether or not structural magnetic resonance imaging (sMRI) data support the DSM-5 proposal of an autism spectrum disorder (ASD) diagnostic category, and whether or not classical DSM-IV autistic disorder (AD) and Asperger syndrome (AS) categories should be subsumed into it. The most replicated sMRI findings in patients with ASD compared with healthy controls are increased total brain volume in early childhood and decreased corpus callosum volume. Regarding the notion of a spectrum, some studies support that AS and AD are similar but 'quantitatively different' diagnostic categories, whereas others support that they are 'qualitatively different' entities with specific brain structural abnormalities. It seems that there are still not enough arguments from sMRI data for or against subsuming DSM-IV categories under a single ASD category. En ligne : http://dx.doi.org/10.1016/j.rasd.2012.08.013 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=186 [article] Structural magnetic resonance imaging data do not help support DSM-5 autism spectrum disorder category [Texte imprimé et/ou numérique] / Laura PINA-CAMACHO, Auteur ; Sonia VILLERO, Auteur ; Leticia BOADA, Auteur ; David FRAGUAS, Auteur ; Joost JANSSEN, Auteur ; María MAYORAL, Auteur ; Cloe LLORENTE, Auteur ; Celso ARANGO, Auteur ; Mara PARELLADA, Auteur . - 2013 . - p.333-343. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 7-2 (February 2013) . - p.333-343 Mots-clés : Autism spectrum disorder  Autistic disorder  Asperger syndrome  Structural magnetic resonance imaging  DSM-5 Index. décimale : PER Périodiques Résumé : This systematic review aims to determine whether or not structural magnetic resonance imaging (sMRI) data support the DSM-5 proposal of an autism spectrum disorder (ASD) diagnostic category, and whether or not classical DSM-IV autistic disorder (AD) and Asperger syndrome (AS) categories should be subsumed into it. The most replicated sMRI findings in patients with ASD compared with healthy controls are increased total brain volume in early childhood and decreased corpus callosum volume. Regarding the notion of a spectrum, some studies support that AS and AD are similar but 'quantitatively different' diagnostic categories, whereas others support that they are 'qualitatively different' entities with specific brain structural abnormalities. It seems that there are still not enough arguments from sMRI data for or against subsuming DSM-IV categories under a single ASD category. En ligne : http://dx.doi.org/10.1016/j.rasd.2012.08.013 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=186

The affective dimension of early-onset psychosis and its relationship with suicide / Vanessa SANCHEZ-GISTAU in Journal of Child Psychology and Psychiatry, 56-7 (July 2015)  

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