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Auteur Gail A. ALVARES |
Documents disponibles écrits par cet auteur (29)
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Parental perspectives of the everyday experiences of uncertainty among young children on the autism spectrum / Claudia S. Y. ONG in Research in Autism Spectrum Disorders, 101 (March 2023)
[article]
Titre : Parental perspectives of the everyday experiences of uncertainty among young children on the autism spectrum Type de document : Texte imprimé et/ou numérique Auteurs : Claudia S. Y. ONG, Auteur ; Iliana MAGIATI, Auteur ; Murray T. MAYBERY, Auteur ; Jacqui RODGERS, Auteur ; Mirko ULJAREVIC, Auteur ; Gail A. ALVARES, Auteur Article en page(s) : 102087 Langues : Anglais (eng) Mots-clés : Autism Anxiety Intolerance of uncertainty Qualitative study Index. décimale : PER Périodiques Résumé : Background Anxiety commonly co-occurs in autism. Exploring and understanding potential underpinning mechanisms contributing to and maintaining anxiety in the early years is important in managing anxiety. Intolerance of uncertainty (IU), a tendency to find uncertainty difficult, is a transdiagnostic mechanism contributing to anxiety, but little is known about how IU may be experienced in young children on the autism spectrum. This study investigated parental perspectives of children’s experiences of uncertainty. Method Parents of 13 children aged 4 “7 years participated in focus groups. Participants were recruited until data saturation was reached. Thematic analysis using a framework analysis approach was employed, with 18 themes identified. Results Parents perceived IU as an important construct that often manifested in their children’s heightened emotional and behavioural reactivity. Parents described responses to uncertainty as more intense for their children on the spectrum compared to non-autistic children, with some behaviours associated with or exacerbated by autism characteristics. Parents also described various strategies aimed to reduce uncertainty or increase children’s ability to cope with uncertainty. Most reported that difficulties with uncertainty had a significant negative impact on family well-being. Conclusions Given that IU can present early in life for children on the spectrum, with distressing experiences that can negatively impact everyday life and well-being, further research into early and targeted interventions is needed. The findings highlight the support needs for families of young children on the spectrum and will inform the evaluation of a targeted parent-mediated intervention to support children in managing difficulties with uncertainty. En ligne : https://doi.org/10.1016/j.rasd.2022.102087 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=492
in Research in Autism Spectrum Disorders > 101 (March 2023) . - 102087[article] Parental perspectives of the everyday experiences of uncertainty among young children on the autism spectrum [Texte imprimé et/ou numérique] / Claudia S. Y. ONG, Auteur ; Iliana MAGIATI, Auteur ; Murray T. MAYBERY, Auteur ; Jacqui RODGERS, Auteur ; Mirko ULJAREVIC, Auteur ; Gail A. ALVARES, Auteur . - 102087.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 101 (March 2023) . - 102087
Mots-clés : Autism Anxiety Intolerance of uncertainty Qualitative study Index. décimale : PER Périodiques Résumé : Background Anxiety commonly co-occurs in autism. Exploring and understanding potential underpinning mechanisms contributing to and maintaining anxiety in the early years is important in managing anxiety. Intolerance of uncertainty (IU), a tendency to find uncertainty difficult, is a transdiagnostic mechanism contributing to anxiety, but little is known about how IU may be experienced in young children on the autism spectrum. This study investigated parental perspectives of children’s experiences of uncertainty. Method Parents of 13 children aged 4 “7 years participated in focus groups. Participants were recruited until data saturation was reached. Thematic analysis using a framework analysis approach was employed, with 18 themes identified. Results Parents perceived IU as an important construct that often manifested in their children’s heightened emotional and behavioural reactivity. Parents described responses to uncertainty as more intense for their children on the spectrum compared to non-autistic children, with some behaviours associated with or exacerbated by autism characteristics. Parents also described various strategies aimed to reduce uncertainty or increase children’s ability to cope with uncertainty. Most reported that difficulties with uncertainty had a significant negative impact on family well-being. Conclusions Given that IU can present early in life for children on the spectrum, with distressing experiences that can negatively impact everyday life and well-being, further research into early and targeted interventions is needed. The findings highlight the support needs for families of young children on the spectrum and will inform the evaluation of a targeted parent-mediated intervention to support children in managing difficulties with uncertainty. En ligne : https://doi.org/10.1016/j.rasd.2022.102087 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=492 Prenatal maternal stress events and phenotypic outcomes in Autism Spectrum Disorder / Kandice J. VARCIN in Autism Research, 10-11 (November 2017)
[article]
Titre : Prenatal maternal stress events and phenotypic outcomes in Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Kandice J. VARCIN, Auteur ; Gail A. ALVARES, Auteur ; Mirko ULJAREVIC, Auteur ; Andrew J. O. WHITEHOUSE, Auteur Article en page(s) : p.1866-1877 Langues : Anglais (eng) Mots-clés : autism maternal stress prenatal heterogeneity Index. décimale : PER Périodiques Résumé : There is significant heterogeneity amongst individuals with Autism Spectrum Disorder (ASD) in symptom presentation and severity. An understanding of the factors that contribute to and modulate symptom severity are critical to informing prognosis, stratification, and treatment decisions. Maternal prenatal stress exposure is a nonspecific risk factor for a wide array of neurodevelopmental outcomes in subsequent offspring. Emerging evidence suggests that prenatal maternal stress may increase ASD risk and contribute to variability in autism-like traits in the general population. In the current study, we aimed to determine whether prenatal maternal exposure to stressful life events is associated with symptom severity amongst individuals with ASD. We performed multiple regression analyses to examine associations between retrospectively recalled maternal prenatal stressful life events and the severity of ASD-associated symptoms in 174 children with ASD (Mage?=?9.09 years; SD?=?3.81). ASD-related symptom severity was measured using the Social Responsiveness Scale and communication abilities were measured using the Children's Communication Checklist. Exposure to prenatal stressful life events was a significant predictor of ASD-related symptom severity (t?=?2.014; P?=?.048) and communication abilities (t?=??2.925; P?=?.004) amongst children with ASD, even after controlling for a range of sociodemographic and obstetric variables. Follow-up analyses demonstrated significant increases in symptom severity only in the context of multiple (two or more) prenatal stressful life events. Together, these findings indicate that ASD, in the context of prenatal maternal stress exposure, may be associated with a more severe phenotype, particularly when there are multiple prenatal exposures. Autism Res 2017, 10: 1866–1877. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. Lay Summary There is emerging evidence that prenatal maternal stress may increase the risk for Autism Spectrum Disorder (ASD) and contribute to variability in autism-like traits in the general population. Here, we found that more stressful life events experienced during pregnancy was associated with more severe ASD-related symptoms and poorer communication abilities amongst children with ASD. The results from this study suggest that prenatal maternal stress exposure and its sequelae may contribute to variability in symptom severity amongst children with ASD. En ligne : http://dx.doi.org/10.1002/aur.1830 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322
in Autism Research > 10-11 (November 2017) . - p.1866-1877[article] Prenatal maternal stress events and phenotypic outcomes in Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Kandice J. VARCIN, Auteur ; Gail A. ALVARES, Auteur ; Mirko ULJAREVIC, Auteur ; Andrew J. O. WHITEHOUSE, Auteur . - p.1866-1877.
Langues : Anglais (eng)
in Autism Research > 10-11 (November 2017) . - p.1866-1877
Mots-clés : autism maternal stress prenatal heterogeneity Index. décimale : PER Périodiques Résumé : There is significant heterogeneity amongst individuals with Autism Spectrum Disorder (ASD) in symptom presentation and severity. An understanding of the factors that contribute to and modulate symptom severity are critical to informing prognosis, stratification, and treatment decisions. Maternal prenatal stress exposure is a nonspecific risk factor for a wide array of neurodevelopmental outcomes in subsequent offspring. Emerging evidence suggests that prenatal maternal stress may increase ASD risk and contribute to variability in autism-like traits in the general population. In the current study, we aimed to determine whether prenatal maternal exposure to stressful life events is associated with symptom severity amongst individuals with ASD. We performed multiple regression analyses to examine associations between retrospectively recalled maternal prenatal stressful life events and the severity of ASD-associated symptoms in 174 children with ASD (Mage?=?9.09 years; SD?=?3.81). ASD-related symptom severity was measured using the Social Responsiveness Scale and communication abilities were measured using the Children's Communication Checklist. Exposure to prenatal stressful life events was a significant predictor of ASD-related symptom severity (t?=?2.014; P?=?.048) and communication abilities (t?=??2.925; P?=?.004) amongst children with ASD, even after controlling for a range of sociodemographic and obstetric variables. Follow-up analyses demonstrated significant increases in symptom severity only in the context of multiple (two or more) prenatal stressful life events. Together, these findings indicate that ASD, in the context of prenatal maternal stress exposure, may be associated with a more severe phenotype, particularly when there are multiple prenatal exposures. Autism Res 2017, 10: 1866–1877. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. Lay Summary There is emerging evidence that prenatal maternal stress may increase the risk for Autism Spectrum Disorder (ASD) and contribute to variability in autism-like traits in the general population. Here, we found that more stressful life events experienced during pregnancy was associated with more severe ASD-related symptoms and poorer communication abilities amongst children with ASD. The results from this study suggest that prenatal maternal stress exposure and its sequelae may contribute to variability in symptom severity amongst children with ASD. En ligne : http://dx.doi.org/10.1002/aur.1830 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322 Prevalence of Motor Difficulties in Autism Spectrum Disorder: Analysis of a Population-Based Cohort / Melissa K. LICARI in Autism Research, 13-2 (February 2020)
[article]
Titre : Prevalence of Motor Difficulties in Autism Spectrum Disorder: Analysis of a Population-Based Cohort Type de document : Texte imprimé et/ou numérique Auteurs : Melissa K. LICARI, Auteur ; Gail A. ALVARES, Auteur ; Kandice J. VARCIN, Auteur ; Kiah EVANS, Auteur ; Dominique CLEARY, Auteur ; Siobhan L. REID, Auteur ; Emma J. GLASSON, Auteur ; Keely BEBBINGTON, Auteur ; Jess E. REYNOLDS, Auteur ; John WRAY, Auteur ; Andrew J. O. WHITEHOUSE, Auteur Article en page(s) : p.298-306 Langues : Anglais (eng) Mots-clés : autism spectrum disorder developmental disabilities motor disorders motor skills movement Index. décimale : PER Périodiques Résumé : Motor impairment is not currently included in the diagnostic criteria or evaluation of autism. This reflects the lack of large-scale studies demonstrating its prominence to advocate for change. We examined the prevalence of motor difficulties at the time of diagnosis in a large sample of children with autism utilizing standardized assessment, and the relationship between motor difficulties, core autism symptomology, and other prominent clinical features. Vineland Adaptive Behavior Scales were administered to children from the Western Australian Register for Autism Spectrum Disorders aged =6 years (N = 2,084; 81.2% males, 18.8% females). Prevalence of motor difficulties was quantified based on scores from the motor domain of the Vineland and then compared to other domains of functioning within the Vineland (communication, daily living, and socialization), the DSM criteria, intellectual level, age, and gender. Scores on the Vineland indicated that 35.4% of the sample met criteria for motor difficulties (standard score <70), a rate almost as common as intellectual impairment (37.7%). Motor difficulties were reported by diagnosing clinicians in only 1.34% of cases. Motor difficulties were common in those cases meeting diagnostic criteria for impairments in nonverbal behavior and the presence of restricted and repetitive behaviors. The prevalence of motor difficulties also increased with increasing age of diagnosis (P < 0.001). Findings from the present study highlight the need for further consideration of motor difficulties as a distinct specifier within the diagnostic criteria for ASD. Autism Res 2020, 13: 298-306. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: In this population-based cohort that included 2,084 children with autism aged =6 years, over one-third met the criteria for motor difficulties, a rate almost as common as intellectual disability. This study demonstrates that motor difficulties are a prominent feature of the autism phenotype requiring further consideration in both the diagnostic criteria and evaluation of autism. En ligne : http://dx.doi.org/10.1002/aur.2230 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=420
in Autism Research > 13-2 (February 2020) . - p.298-306[article] Prevalence of Motor Difficulties in Autism Spectrum Disorder: Analysis of a Population-Based Cohort [Texte imprimé et/ou numérique] / Melissa K. LICARI, Auteur ; Gail A. ALVARES, Auteur ; Kandice J. VARCIN, Auteur ; Kiah EVANS, Auteur ; Dominique CLEARY, Auteur ; Siobhan L. REID, Auteur ; Emma J. GLASSON, Auteur ; Keely BEBBINGTON, Auteur ; Jess E. REYNOLDS, Auteur ; John WRAY, Auteur ; Andrew J. O. WHITEHOUSE, Auteur . - p.298-306.
Langues : Anglais (eng)
in Autism Research > 13-2 (February 2020) . - p.298-306
Mots-clés : autism spectrum disorder developmental disabilities motor disorders motor skills movement Index. décimale : PER Périodiques Résumé : Motor impairment is not currently included in the diagnostic criteria or evaluation of autism. This reflects the lack of large-scale studies demonstrating its prominence to advocate for change. We examined the prevalence of motor difficulties at the time of diagnosis in a large sample of children with autism utilizing standardized assessment, and the relationship between motor difficulties, core autism symptomology, and other prominent clinical features. Vineland Adaptive Behavior Scales were administered to children from the Western Australian Register for Autism Spectrum Disorders aged =6 years (N = 2,084; 81.2% males, 18.8% females). Prevalence of motor difficulties was quantified based on scores from the motor domain of the Vineland and then compared to other domains of functioning within the Vineland (communication, daily living, and socialization), the DSM criteria, intellectual level, age, and gender. Scores on the Vineland indicated that 35.4% of the sample met criteria for motor difficulties (standard score <70), a rate almost as common as intellectual impairment (37.7%). Motor difficulties were reported by diagnosing clinicians in only 1.34% of cases. Motor difficulties were common in those cases meeting diagnostic criteria for impairments in nonverbal behavior and the presence of restricted and repetitive behaviors. The prevalence of motor difficulties also increased with increasing age of diagnosis (P < 0.001). Findings from the present study highlight the need for further consideration of motor difficulties as a distinct specifier within the diagnostic criteria for ASD. Autism Res 2020, 13: 298-306. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: In this population-based cohort that included 2,084 children with autism aged =6 years, over one-third met the criteria for motor difficulties, a rate almost as common as intellectual disability. This study demonstrates that motor difficulties are a prominent feature of the autism phenotype requiring further consideration in both the diagnostic criteria and evaluation of autism. En ligne : http://dx.doi.org/10.1002/aur.2230 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=420 A prospective study of fetal head growth, autistic traits and autism spectrum disorder / Laura M. E. BLANKEN in Autism Research, 11-4 (April 2018)
[article]
Titre : A prospective study of fetal head growth, autistic traits and autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Laura M. E. BLANKEN, Auteur ; A. DASS, Auteur ; Gail A. ALVARES, Auteur ; J. VAN DER ENDE, Auteur ; Nikita K. SCHOEMAKER, Auteur ; H. EL MARROUN, Auteur ; M. HICKEY, Auteur ; C. PENNELL, Auteur ; S. WHITE, Auteur ; M. T. MAYBERY, Auteur ; Cheryl DISSANAYAKE, Auteur ; Vincent W.V. JADDOE, Auteur ; F. C. VERHULST, Auteur ; H. TIEMEIER, Auteur ; W. MCINTOSH, Auteur ; T. WHITE, Auteur ; Andrew J. O. WHITEHOUSE, Auteur Article en page(s) : p.602-612 Langues : Anglais (eng) Mots-clés : brain growth head circumference pregnancy prenatal ultrasound Index. décimale : PER Périodiques Résumé : Altered trajectories of brain growth are often reported in Autism Spectrum Disorder (ASD), particularly during the first year of life. However, less is known about prenatal head growth trajectories, and no study has examined the relation with postnatal autistic symptom severity. The current study prospectively examined the association between fetal head growth and the spectrum of autistic symptom severity in two large population-based cohorts, including a sample of individuals with clinically diagnosed ASD. This study included 3,820 children from two longitudinal prenatal cohorts in The Netherlands and Australia, comprising 60 individuals with a confirmed diagnosis of ASD. Latent growth curve models were used to examine the relationship between fetal head circumference measured at three different time points and autistic traits measured in postnatal life using either the Social Responsiveness Scale or the Autism-Spectrum Quotient. While lower initial prenatal HC was weakly associated with increasing autistic traits in the Dutch cohort, this relationship was not observed in the Australian cohort, nor when the two cohorts were analysed together. No differences in prenatal head growth were found between individuals with ASD and controls. This large population-based study identified no consistent association across two cohorts between prenatal head growth and postnatal autistic traits. Our mixed findings suggest that further research in this area is needed. Autism Res 2018, 11: 602-612. (c) 2018 The Authors Autism Research published by International Society for Autism Research and Wiley Periodicals, Inc. LAY SUMMARY: It is not known whether different patterns of postnatal brain growth in Autism Spectrum Disorder (ASD) also occurs prenatally. We examined fetal head growth and autistic symptoms in two large groups from The Netherlands and Australia. Lower initial prenatal head circumference was associated with autistic traits in the Dutch, but not the Australian, group. No differences in head growth were found in individuals with ASD and controls when the data was combined. Our mixed findings suggest that more research in this area is needed. En ligne : http://dx.doi.org/10.1002/aur.1921 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=358
in Autism Research > 11-4 (April 2018) . - p.602-612[article] A prospective study of fetal head growth, autistic traits and autism spectrum disorder [Texte imprimé et/ou numérique] / Laura M. E. BLANKEN, Auteur ; A. DASS, Auteur ; Gail A. ALVARES, Auteur ; J. VAN DER ENDE, Auteur ; Nikita K. SCHOEMAKER, Auteur ; H. EL MARROUN, Auteur ; M. HICKEY, Auteur ; C. PENNELL, Auteur ; S. WHITE, Auteur ; M. T. MAYBERY, Auteur ; Cheryl DISSANAYAKE, Auteur ; Vincent W.V. JADDOE, Auteur ; F. C. VERHULST, Auteur ; H. TIEMEIER, Auteur ; W. MCINTOSH, Auteur ; T. WHITE, Auteur ; Andrew J. O. WHITEHOUSE, Auteur . - p.602-612.
Langues : Anglais (eng)
in Autism Research > 11-4 (April 2018) . - p.602-612
Mots-clés : brain growth head circumference pregnancy prenatal ultrasound Index. décimale : PER Périodiques Résumé : Altered trajectories of brain growth are often reported in Autism Spectrum Disorder (ASD), particularly during the first year of life. However, less is known about prenatal head growth trajectories, and no study has examined the relation with postnatal autistic symptom severity. The current study prospectively examined the association between fetal head growth and the spectrum of autistic symptom severity in two large population-based cohorts, including a sample of individuals with clinically diagnosed ASD. This study included 3,820 children from two longitudinal prenatal cohorts in The Netherlands and Australia, comprising 60 individuals with a confirmed diagnosis of ASD. Latent growth curve models were used to examine the relationship between fetal head circumference measured at three different time points and autistic traits measured in postnatal life using either the Social Responsiveness Scale or the Autism-Spectrum Quotient. While lower initial prenatal HC was weakly associated with increasing autistic traits in the Dutch cohort, this relationship was not observed in the Australian cohort, nor when the two cohorts were analysed together. No differences in prenatal head growth were found between individuals with ASD and controls. This large population-based study identified no consistent association across two cohorts between prenatal head growth and postnatal autistic traits. Our mixed findings suggest that further research in this area is needed. Autism Res 2018, 11: 602-612. (c) 2018 The Authors Autism Research published by International Society for Autism Research and Wiley Periodicals, Inc. LAY SUMMARY: It is not known whether different patterns of postnatal brain growth in Autism Spectrum Disorder (ASD) also occurs prenatally. We examined fetal head growth and autistic symptoms in two large groups from The Netherlands and Australia. Lower initial prenatal head circumference was associated with autistic traits in the Dutch, but not the Australian, group. No differences in head growth were found in individuals with ASD and controls when the data was combined. Our mixed findings suggest that more research in this area is needed. En ligne : http://dx.doi.org/10.1002/aur.1921 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=358 A randomised controlled trial of an iPad-based application to complement early behavioural intervention in Autism Spectrum Disorder / Andrew J. O. WHITEHOUSE in Journal of Child Psychology and Psychiatry, 58-9 (September 2017)
[article]
Titre : A randomised controlled trial of an iPad-based application to complement early behavioural intervention in Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Andrew J. O. WHITEHOUSE, Auteur ; Joanna GRANICH, Auteur ; Gail A. ALVARES, Auteur ; Margherita L. BUSACCA, Auteur ; Matthew N. COOPER, Auteur ; Alena DASS, Auteur ; Thi DUONG, Auteur ; Rajes HARPER, Auteur ; Wendy MARSHALL, Auteur ; Amanda RICHDALE, Auteur ; Tania RODWELL, Auteur ; David TREMBATH, Auteur ; Pratibha VELLANKI, Auteur ; Dennis W. MOORE, Auteur ; Angelika ANDERSON, Auteur Article en page(s) : p.1042-1052 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder randomised controlled trial early intervention computer-assisted learning Index. décimale : PER Périodiques Résumé : Background Technology-based interventions for Autism Spectrum Disorder (ASD) have proliferated, but few have been evaluated within the context of a randomised controlled trial (RCT). This RCT evaluated the efficacy of one technology-based early intervention programme (Therapy Outcomes By You; TOBY) in young children with ASD. Methods TOBY is an app-based learning curriculum designed for children and parents as a complement to early behavioural intervention. Eighty children (16 female) were recruited to this RCT within 12 months of receiving a diagnosis of ASD (M age = 3.38; SD = 0.69) and randomised to receive either treatment-as-usual (community-based intervention, n = 39) or the TOBY therapy (at least 20 min/day) plus treatment-as-usual (n = 41) for a period of 6 months. Outcomes were assessed at 3 and 6 months postbaseline. (Australian New Zealand Clinical Trials Registry: ACTRN12614000738628; www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=365463). Results Children in the TOBY intervention group averaged 19 min/day engaging with the app in the first 3 months, but only 2 min/day during the second 3 months. There was no group difference in scores on the primary outcome, the Autism Treatment Evaluation Checklist, at either the 3- or 6-month follow-up. However, significant improvements at the 6-month follow-up were observed in the TOBY intervention group relative to the treatment-as-usual group on three secondary outcomes: the Fine Motor and Visual Reception subscales of the Mullen Scale of Early Learning and the Total Words Understood scale of the MacArthur-Bates Communicative Development Index. Statistical trends towards improvement in the TOBY intervention group were observed on measures of adaptive function, although these decreased in magnitude from the 3- to 6-month follow-up. Conclusions This study provides evidence that technology-based interventions may provide a relatively low-cost addition to existing therapist-delivered interventions for children with ASD. However, sustained use of the app over the full 6-month period was a challenge for most families. En ligne : http://dx.doi.org/10.1111/jcpp.12752 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=317
in Journal of Child Psychology and Psychiatry > 58-9 (September 2017) . - p.1042-1052[article] A randomised controlled trial of an iPad-based application to complement early behavioural intervention in Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Andrew J. O. WHITEHOUSE, Auteur ; Joanna GRANICH, Auteur ; Gail A. ALVARES, Auteur ; Margherita L. BUSACCA, Auteur ; Matthew N. COOPER, Auteur ; Alena DASS, Auteur ; Thi DUONG, Auteur ; Rajes HARPER, Auteur ; Wendy MARSHALL, Auteur ; Amanda RICHDALE, Auteur ; Tania RODWELL, Auteur ; David TREMBATH, Auteur ; Pratibha VELLANKI, Auteur ; Dennis W. MOORE, Auteur ; Angelika ANDERSON, Auteur . - p.1042-1052.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 58-9 (September 2017) . - p.1042-1052
Mots-clés : Autism Spectrum Disorder randomised controlled trial early intervention computer-assisted learning Index. décimale : PER Périodiques Résumé : Background Technology-based interventions for Autism Spectrum Disorder (ASD) have proliferated, but few have been evaluated within the context of a randomised controlled trial (RCT). This RCT evaluated the efficacy of one technology-based early intervention programme (Therapy Outcomes By You; TOBY) in young children with ASD. Methods TOBY is an app-based learning curriculum designed for children and parents as a complement to early behavioural intervention. Eighty children (16 female) were recruited to this RCT within 12 months of receiving a diagnosis of ASD (M age = 3.38; SD = 0.69) and randomised to receive either treatment-as-usual (community-based intervention, n = 39) or the TOBY therapy (at least 20 min/day) plus treatment-as-usual (n = 41) for a period of 6 months. Outcomes were assessed at 3 and 6 months postbaseline. (Australian New Zealand Clinical Trials Registry: ACTRN12614000738628; www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=365463). Results Children in the TOBY intervention group averaged 19 min/day engaging with the app in the first 3 months, but only 2 min/day during the second 3 months. There was no group difference in scores on the primary outcome, the Autism Treatment Evaluation Checklist, at either the 3- or 6-month follow-up. However, significant improvements at the 6-month follow-up were observed in the TOBY intervention group relative to the treatment-as-usual group on three secondary outcomes: the Fine Motor and Visual Reception subscales of the Mullen Scale of Early Learning and the Total Words Understood scale of the MacArthur-Bates Communicative Development Index. Statistical trends towards improvement in the TOBY intervention group were observed on measures of adaptive function, although these decreased in magnitude from the 3- to 6-month follow-up. Conclusions This study provides evidence that technology-based interventions may provide a relatively low-cost addition to existing therapist-delivered interventions for children with ASD. However, sustained use of the app over the full 6-month period was a challenge for most families. En ligne : http://dx.doi.org/10.1111/jcpp.12752 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=317 Reduced goal-directed action control in autism spectrum disorder / Gail A. ALVARES in Autism Research, 9-12 (December 2016)
PermalinkReduced heart rate variability in adults with autism spectrum disorder / R. THAPA in Autism Research, 12-6 (June 2019)
PermalinkRelationship between early motor milestones and severity of restricted and repetitive behaviors in children and adolescents with autism spectrum disorder / Mirko ULJAREVIC in Autism Research, 10-6 (June 2017)
PermalinkShort report: relationship between restricted and repetitive behaviours in children with autism spectrum disorder and their parents / M. ULJAREVIC in Molecular Autism, 7 (2016)
PermalinkSymptom severity in autism spectrum disorder is related to the frequency and severity of nausea and vomiting during pregnancy: a retrospective case-control study / Andrew J. O. WHITEHOUSE in Molecular Autism, 9 (2018)
PermalinkThe course and prognostic capability of motor difficulties in infants showing early signs of autism / M. K. LICARI in Autism Research, 14-8 (August 2021)
PermalinkThe effects of a course of intranasal oxytocin on social behaviors in youth diagnosed with autism spectrum disorders: a randomized controlled trial / Adam J. GUASTELLA in Journal of Child Psychology and Psychiatry, 56-4 (April 2015)
PermalinkThe misnomer of 'high functioning autism': Intelligence is an imprecise predictor of functional abilities at diagnosis / Gail A. ALVARES in Autism, 24-1 (January 2020)
PermalinkUnderstanding the heterogeneity of anxiety in autistic youth: A person-centered approach / Emily SPACKMAN in Autism Research, 15-9 (September 2022)
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