Deprivation and psychopathology in the Fragile Families Study: A 15-year longitudinal investigation / Adam Bryant MILLER in Journal of Child Psychology and Psychiatry, 62-4 (April 2021)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 62-4 (April 2021) . - p.382-391 Titre : Deprivation and psychopathology in the Fragile Families Study: A 15-year longitudinal investigation Type de document : Texte imprimé et/ou numérique Auteurs : Adam Bryant MILLER, Auteur ; Laura MACHLIN, Auteur ; Katie A. MCLAUGHLIN, Auteur ; Margaret A. SHERIDAN, Auteur Article en page(s) : p.382-391 Langues : Anglais (eng) Mots-clés : Deprivation  adversity  externalizing psychopathology  internalizing psychopathology  language  threat Index. décimale : PER Périodiques Résumé : BACKGROUND: Early adversity consistently predicts youth psychopathology. However, the pathways linking unique dimensions of early adversity, such as deprivation, to psychopathology are understudied. Here, we evaluate a theoretical model linking early deprivation exposure with psychopathology prospectively through language ability. METHODS: Participants included 2,301 youth (47.5% female) enrolled in the Fragile Families and Child Wellbeing Study. We include data from assessment points at ages 1, 3, 5, 9, and 15. Latent factors for deprivation and threat were modeled from multiple indicators at ages 1 and 3. Youth language ability was assessed at Age 5. Indicators of psychopathology were assessed at ages 5, 9, and 15. A structural equation model tested longitudinal paths to internalizing and externalizing psychopathology from experiences of deprivation and threat. RESULTS: Deprivation from birth to Age 3 was associated with an indirect effect on internalizing and externalizing symptoms in early childhood (Age 5), later childhood (Age 9), and adolescence (Age 15) via language ability in early childhood (Age 5). Early threat exposure was associated with increased internalizing and externalizing psychopathology across all ages. There was no significant indirect effect from threat to psychopathology via language ability. CONCLUSIONS: The effects of deprivation on psychopathology during early childhood, late childhood, and adolescence are explained, in part, through early childhood language ability. Results provide insight into language ability as a possible opportunity for intervention. En ligne : http://dx.doi.org/10.1111/jcpp.13260 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=445 [article] Deprivation and psychopathology in the Fragile Families Study: A 15-year longitudinal investigation [Texte imprimé et/ou numérique] / Adam Bryant MILLER, Auteur ; Laura MACHLIN, Auteur ; Katie A. MCLAUGHLIN, Auteur ; Margaret A. SHERIDAN, Auteur . - p.382-391. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 62-4 (April 2021) . - p.382-391 Mots-clés : Deprivation  adversity  externalizing psychopathology  internalizing psychopathology  language  threat Index. décimale : PER Périodiques Résumé : BACKGROUND: Early adversity consistently predicts youth psychopathology. However, the pathways linking unique dimensions of early adversity, such as deprivation, to psychopathology are understudied. Here, we evaluate a theoretical model linking early deprivation exposure with psychopathology prospectively through language ability. METHODS: Participants included 2,301 youth (47.5% female) enrolled in the Fragile Families and Child Wellbeing Study. We include data from assessment points at ages 1, 3, 5, 9, and 15. Latent factors for deprivation and threat were modeled from multiple indicators at ages 1 and 3. Youth language ability was assessed at Age 5. Indicators of psychopathology were assessed at ages 5, 9, and 15. A structural equation model tested longitudinal paths to internalizing and externalizing psychopathology from experiences of deprivation and threat. RESULTS: Deprivation from birth to Age 3 was associated with an indirect effect on internalizing and externalizing symptoms in early childhood (Age 5), later childhood (Age 9), and adolescence (Age 15) via language ability in early childhood (Age 5). Early threat exposure was associated with increased internalizing and externalizing psychopathology across all ages. There was no significant indirect effect from threat to psychopathology via language ability. CONCLUSIONS: The effects of deprivation on psychopathology during early childhood, late childhood, and adolescence are explained, in part, through early childhood language ability. Results provide insight into language ability as a possible opportunity for intervention. En ligne : http://dx.doi.org/10.1111/jcpp.13260 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=445

Environmental determinants of physiological reactivity to stress: The interacting effects of early life deprivation, caregiving quality, and stressful life events / Mark WADE in Development and Psychopathology, 32-5 (December 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-5 (December 2020) . - p.1732-1742 Titre : Environmental determinants of physiological reactivity to stress: The interacting effects of early life deprivation, caregiving quality, and stressful life events Type de document : Texte imprimé et/ou numérique Auteurs : Mark WADE, Auteur ; Margaret A. SHERIDAN, Auteur ; Charles H. ZEANAH, Auteur ; Nathan A. FOX, Auteur ; Charles A. NELSON, Auteur ; Katie A. MCLAUGHLIN, Auteur Article en page(s) : p.1732-1742 Langues : Anglais (eng) Mots-clés : Adolescent  Child  *Child, Institutionalized  Foster Home Care  Humans  Hydrocortisone  Hypothalamo-Hypophyseal System  *Pituitary-Adrenal System  Psychosocial Deprivation  Stress, Psychological  *HPA-axis  *developmental psychobiology  *institutional rearing  *neglect  *stress reactivity  *sympathetic nervous system Index. décimale : PER Périodiques Résumé : Children who spend their early lives in institutions experience profound psychosocial deprivation that is associated with altered stress response system development. Here, we used data from a longitudinal randomized controlled trial of foster care for institutionally reared children to examine whether caregiving quality and stressful life events (SLEs) in early adolescence (age 12) influence patterns of hypothalamic-pituitary-adrenal (HPA) axis and sympathetic nervous system (SNS) reactivity. Controlling for the effect of institutional care, higher caregiving quality at age 12 was associated with heightened cortisol and SNS reactivity. However, moderation analysis revealed that the latter effect was only observed among never-institutionalized children, whereas ever-institutionalized children demonstrated a persistently blunted SNS response regardless of recent caregiving quality. Among institutionally reared children, SLEs interacted with prior random assignment to foster care, such that those placed in foster care early in development had a SNS response that approximated never-institutionalized children when SLEs at age 12 were low. In contrast, SNS reactivity was persistently blunted among those with prolonged deprivation, regardless of recent SLEs. Early-life deprivation is associated with persistent blunting of stress response systems, but normalization may be achievable if SLEs are limited following placement into enriched family-based care. En ligne : http://dx.doi.org/10.1017/s0954579420001327 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=437 [article] Environmental determinants of physiological reactivity to stress: The interacting effects of early life deprivation, caregiving quality, and stressful life events [Texte imprimé et/ou numérique] / Mark WADE, Auteur ; Margaret A. SHERIDAN, Auteur ; Charles H. ZEANAH, Auteur ; Nathan A. FOX, Auteur ; Charles A. NELSON, Auteur ; Katie A. MCLAUGHLIN, Auteur . - p.1732-1742. Langues : Anglais (eng) in Development and Psychopathology > 32-5 (December 2020) . - p.1732-1742 Mots-clés : Adolescent  Child  *Child, Institutionalized  Foster Home Care  Humans  Hydrocortisone  Hypothalamo-Hypophyseal System  *Pituitary-Adrenal System  Psychosocial Deprivation  Stress, Psychological  *HPA-axis  *developmental psychobiology  *institutional rearing  *neglect  *stress reactivity  *sympathetic nervous system Index. décimale : PER Périodiques Résumé : Children who spend their early lives in institutions experience profound psychosocial deprivation that is associated with altered stress response system development. Here, we used data from a longitudinal randomized controlled trial of foster care for institutionally reared children to examine whether caregiving quality and stressful life events (SLEs) in early adolescence (age 12) influence patterns of hypothalamic-pituitary-adrenal (HPA) axis and sympathetic nervous system (SNS) reactivity. Controlling for the effect of institutional care, higher caregiving quality at age 12 was associated with heightened cortisol and SNS reactivity. However, moderation analysis revealed that the latter effect was only observed among never-institutionalized children, whereas ever-institutionalized children demonstrated a persistently blunted SNS response regardless of recent caregiving quality. Among institutionally reared children, SLEs interacted with prior random assignment to foster care, such that those placed in foster care early in development had a SNS response that approximated never-institutionalized children when SLEs at age 12 were low. In contrast, SNS reactivity was persistently blunted among those with prolonged deprivation, regardless of recent SLEs. Early-life deprivation is associated with persistent blunting of stress response systems, but normalization may be achievable if SLEs are limited following placement into enriched family-based care. En ligne : http://dx.doi.org/10.1017/s0954579420001327 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=437

Identifying intervention strategies for preventing the mental health consequences of childhood adversity: A modified Delphi study / Leslie R. RITH-NAJARIAN in Development and Psychopathology, 33-2 (May 2021)  

Public ISBD [article]  inDevelopment and Psychopathology > 33-2 (May 2021) . - p.748-765 Titre : Identifying intervention strategies for preventing the mental health consequences of childhood adversity: A modified Delphi study Type de document : Texte imprimé et/ou numérique Auteurs : Leslie R. RITH-NAJARIAN, Auteur ; Noah S. TRIPLETT, Auteur ; John R. WEISZ, Auteur ; Katie A. MCLAUGHLIN, Auteur Année de publication : 2021 Article en page(s) : p.748-765 Langues : Anglais (eng) Mots-clés : Delphi study  childhood adversity  intervention development  prevention  psychopathology Index. décimale : PER Périodiques Résumé : Exposure to childhood adversity is a powerful risk factor for psychopathology. Despite extensive efforts, we have not yet identified effective or scalable interventions that prevent the emergence of mental health problems in children who have experienced adversity. In this modified Delphi study, we identified intervention strategies for effectively targeting both the neurodevelopmental mechanisms linking childhood adversity and psychopathology - including heightened emotional reactivity, difficulties with emotion regulation, blunted reward processing, and social information processing biases, as well as a range of psychopathology symptoms. We iteratively synthesized information from experts in the field and relevant meta-analyses through three surveys, first with experts in intervention development, prevention, and childhood adversity (n = 32), and then within our study team (n = 8). The results produced increasing stability and good consensus on intervention strategy recommendations for specific neurodevelopmental mechanisms and symptom presentations and on strength of evidence ratings of intervention strategies targeting youth and parents. More broadly, our findings highlight how intervention decision making can be informed by meta-analyses, enhanced by aggregate group feedback, saturated before consensus, and persistently subjective or even contradictory. Ultimately, the results converged on several promising intervention strategies for prevention programming with adversity-exposed youth, which will be tested in an upcoming clinical trial. En ligne : http://dx.doi.org/10.1017/s0954579420002059 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=444 [article] Identifying intervention strategies for preventing the mental health consequences of childhood adversity: A modified Delphi study [Texte imprimé et/ou numérique] / Leslie R. RITH-NAJARIAN, Auteur ; Noah S. TRIPLETT, Auteur ; John R. WEISZ, Auteur ; Katie A. MCLAUGHLIN, Auteur . - 2021 . - p.748-765. Langues : Anglais (eng) in Development and Psychopathology > 33-2 (May 2021) . - p.748-765 Mots-clés : Delphi study  childhood adversity  intervention development  prevention  psychopathology Index. décimale : PER Périodiques Résumé : Exposure to childhood adversity is a powerful risk factor for psychopathology. Despite extensive efforts, we have not yet identified effective or scalable interventions that prevent the emergence of mental health problems in children who have experienced adversity. In this modified Delphi study, we identified intervention strategies for effectively targeting both the neurodevelopmental mechanisms linking childhood adversity and psychopathology - including heightened emotional reactivity, difficulties with emotion regulation, blunted reward processing, and social information processing biases, as well as a range of psychopathology symptoms. We iteratively synthesized information from experts in the field and relevant meta-analyses through three surveys, first with experts in intervention development, prevention, and childhood adversity (n = 32), and then within our study team (n = 8). The results produced increasing stability and good consensus on intervention strategy recommendations for specific neurodevelopmental mechanisms and symptom presentations and on strength of evidence ratings of intervention strategies targeting youth and parents. More broadly, our findings highlight how intervention decision making can be informed by meta-analyses, enhanced by aggregate group feedback, saturated before consensus, and persistently subjective or even contradictory. Ultimately, the results converged on several promising intervention strategies for prevention programming with adversity-exposed youth, which will be tested in an upcoming clinical trial. En ligne : http://dx.doi.org/10.1017/s0954579420002059 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=444

Social-cognitive mechanisms in the cycle of violence: Cognitive and affective theory of mind, and externalizing psychopathology in children and adolescents / Charlotte HELENIAK in Development and Psychopathology, 32-2 (May 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-2 (May 2020) . - p.735-750 Titre : Social-cognitive mechanisms in the cycle of violence: Cognitive and affective theory of mind, and externalizing psychopathology in children and adolescents Type de document : Texte imprimé et/ou numérique Auteurs : Charlotte HELENIAK, Auteur ; Katie A. MCLAUGHLIN, Auteur Article en page(s) : p.735-750 Langues : Anglais (eng) Mots-clés : adversity  aggression  externalizing  theory of mind  violence Index. décimale : PER Périodiques Résumé : Children who are victims of interpersonal violence have a markedly elevated risk of engaging in aggressive behavior and perpetrating violence in adolescence and adulthood. Although alterations in social information processing have long been understood as a core mechanism underlying the link between violence exposure and externalizing behavior, scant research has examined more basic social cognition abilities that might underlie this association. To that end, this study examined the associations of interpersonal violence exposure with cognitive and affective theory of mind (ToM), core social-cognitive processes that underlie many aspects of social information processing. In addition, we evaluated whether difficulties with ToM were associated with externalizing psychopathology. Data were collected in a community-based sample of 246 children and adolescents aged 8-16 who had a high concentration of exposure to interpersonal violence. Violence exposure was associated with lower accuracy during cognitive and affective ToM, and the associations persisted after adjusting for co-occurring forms of adversity characterized by deprivation, including poverty and emotional neglect. Poor ToM performance, in turn, was associated with externalizing behaviors. These findings shed light on novel pathways that increase risk for aggression in children who have experienced violence. En ligne : http://dx.doi.org/10.1017/s0954579419000725 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=426 [article] Social-cognitive mechanisms in the cycle of violence: Cognitive and affective theory of mind, and externalizing psychopathology in children and adolescents [Texte imprimé et/ou numérique] / Charlotte HELENIAK, Auteur ; Katie A. MCLAUGHLIN, Auteur . - p.735-750. Langues : Anglais (eng) in Development and Psychopathology > 32-2 (May 2020) . - p.735-750 Mots-clés : adversity  aggression  externalizing  theory of mind  violence Index. décimale : PER Périodiques Résumé : Children who are victims of interpersonal violence have a markedly elevated risk of engaging in aggressive behavior and perpetrating violence in adolescence and adulthood. Although alterations in social information processing have long been understood as a core mechanism underlying the link between violence exposure and externalizing behavior, scant research has examined more basic social cognition abilities that might underlie this association. To that end, this study examined the associations of interpersonal violence exposure with cognitive and affective theory of mind (ToM), core social-cognitive processes that underlie many aspects of social information processing. In addition, we evaluated whether difficulties with ToM were associated with externalizing psychopathology. Data were collected in a community-based sample of 246 children and adolescents aged 8-16 who had a high concentration of exposure to interpersonal violence. Violence exposure was associated with lower accuracy during cognitive and affective ToM, and the associations persisted after adjusting for co-occurring forms of adversity characterized by deprivation, including poverty and emotional neglect. Poor ToM performance, in turn, was associated with externalizing behaviors. These findings shed light on novel pathways that increase risk for aggression in children who have experienced violence. En ligne : http://dx.doi.org/10.1017/s0954579419000725 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=426

Within-person fluctuations in stressful life events, sleep, and anxiety and depression symptoms during adolescence: a multiwave prospective study / Constanza M. VIDAL BUSTAMANTE in Journal of Child Psychology and Psychiatry, 61-10 (October 2020)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 61-10 (October 2020) . - p.1116-1125 Titre : Within-person fluctuations in stressful life events, sleep, and anxiety and depression symptoms during adolescence: a multiwave prospective study Type de document : Texte imprimé et/ou numérique Auteurs : Constanza M. VIDAL BUSTAMANTE, Auteur ; Alexandra M. RODMAN, Auteur ; Meg J. DENNISON, Auteur ; John C. FLOURNOY, Auteur ; Patrick MAIR, Auteur ; Katie A. MCLAUGHLIN, Auteur Article en page(s) : p.1116-1125 Langues : Anglais (eng) Mots-clés : Adolescence  actigraphy  anxiety  depression  longitudinal  sleep  stress Index. décimale : PER Périodiques Résumé : BACKGROUND: Adolescence is characterized by substantial changes in sleep behavior, heightened exposure to stressful life events (SLEs), and elevated risk for internalizing problems like anxiety and depression. Although SLEs are consistently associated with the onset of internalizing psychopathology, the mechanisms underlying this relationship remain poorly understood, especially at the within-person level. Here, we leverage a high-frequency longitudinal design to examine sleep as a potential mechanism linking SLEs to increases in anxiety and depression symptoms over a one-year period. METHODS: Thirty female adolescents aged 15-17 years completed 12 monthly in-laboratory assessments of exposure to SLEs and symptoms of anxiety and depression (n = 355 monthly assessments), and wore an actigraphy wristband for continuous monitoring of sleep for the duration of the study (n = 6,824 sleep days). Multilevel models examined concurrent and lagged within-person associations between SLEs, sleep duration and timing regularity, and anxiety and depression symptoms. RESULTS: Within-person fluctuations in SLEs were associated with variability in sleep duration both concurrently and prospectively, such that when adolescents experienced greater SLEs than was typical for them, they exhibited more variable sleep duration that same month as well as the following month. In turn, within-person increases in sleep duration variability predicted greater anxiety symptoms in the same month and mediated the association between SLEs and anxiety. CONCLUSIONS: These findings highlight sleep disruptions as a mechanism underlying the longitudinal associations between SLEs and anxiety symptoms, and suggest that interventions promoting sleep schedule consistency may help mitigate risk for stress-related psychopathology in adolescence. En ligne : http://dx.doi.org/10.1111/jcpp.13234 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=432 [article] Within-person fluctuations in stressful life events, sleep, and anxiety and depression symptoms during adolescence: a multiwave prospective study [Texte imprimé et/ou numérique] / Constanza M. VIDAL BUSTAMANTE, Auteur ; Alexandra M. RODMAN, Auteur ; Meg J. DENNISON, Auteur ; John C. FLOURNOY, Auteur ; Patrick MAIR, Auteur ; Katie A. MCLAUGHLIN, Auteur . - p.1116-1125. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 61-10 (October 2020) . - p.1116-1125 Mots-clés : Adolescence  actigraphy  anxiety  depression  longitudinal  sleep  stress Index. décimale : PER Périodiques Résumé : BACKGROUND: Adolescence is characterized by substantial changes in sleep behavior, heightened exposure to stressful life events (SLEs), and elevated risk for internalizing problems like anxiety and depression. Although SLEs are consistently associated with the onset of internalizing psychopathology, the mechanisms underlying this relationship remain poorly understood, especially at the within-person level. Here, we leverage a high-frequency longitudinal design to examine sleep as a potential mechanism linking SLEs to increases in anxiety and depression symptoms over a one-year period. METHODS: Thirty female adolescents aged 15-17 years completed 12 monthly in-laboratory assessments of exposure to SLEs and symptoms of anxiety and depression (n = 355 monthly assessments), and wore an actigraphy wristband for continuous monitoring of sleep for the duration of the study (n = 6,824 sleep days). Multilevel models examined concurrent and lagged within-person associations between SLEs, sleep duration and timing regularity, and anxiety and depression symptoms. RESULTS: Within-person fluctuations in SLEs were associated with variability in sleep duration both concurrently and prospectively, such that when adolescents experienced greater SLEs than was typical for them, they exhibited more variable sleep duration that same month as well as the following month. In turn, within-person increases in sleep duration variability predicted greater anxiety symptoms in the same month and mediated the association between SLEs and anxiety. CONCLUSIONS: These findings highlight sleep disruptions as a mechanism underlying the longitudinal associations between SLEs and anxiety symptoms, and suggest that interventions promoting sleep schedule consistency may help mitigate risk for stress-related psychopathology in adolescence. En ligne : http://dx.doi.org/10.1111/jcpp.13234 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=432

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