3 recherche sur le mot-clé '*neglect'

The prospective association between stressful life events and inflammation among adolescents with a history of early institutional rearing / Alva TANG in Development and Psychopathology, 32-5 (December 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-5 (December 2020) . - p.1715-1724 Titre : The prospective association between stressful life events and inflammation among adolescents with a history of early institutional rearing Type de document : Texte imprimé et/ou numérique Auteurs : Alva TANG, Auteur ; Mark WADE, Auteur ; Nathan A. FOX, Auteur ; Charles A. NELSON, Auteur ; Charles H. ZEANAH, Auteur ; Natalie SLOPEN, Auteur Article en page(s) : p.1715-1724 Langues : Anglais (eng) Mots-clés : Adolescent  Child  *Child, Institutionalized  Child, Preschool  *Foster Home Care  Humans  Infant  Inflammation  Prospective Studies  Romania  *adolescence  *inflammation  *neglect  *stress sensitization  *stressful life events Index. décimale : PER Périodiques Résumé : Early adversity has been shown to sensitize individuals to the effects of later stress and enhance risk of psychopathology. Using a longitudinal randomized trial of foster care as an alternative to institutional care, we extend the stress sensitization hypothesis to examine whether early institutional rearing sensitizes individuals to stressful events in adolescence engendering chronic low-grade inflammation. At baseline, institutionalized children in Romania (ages 6-31 months) were randomly assigned to foster care or to remain in usual care within institutions. A group of never-institutionalized children was recruited as an in-country comparison sample. At ages 12 and 16, participants reported stressful events. At age 16, Interleukin-6 (IL-6) and C-reactive protein (CRP) were derived from blood spots. Among children assigned to care as usual, more stressful events at age 12, but not age 16, were associated with higher IL-6. In the same group, stressful events at age 16 were associated with higher CRP, though these effects attenuated after adjusting for covariates. These associations were not observed in the foster care or never-institutionalized groups. The findings suggest that heightened inflammation following stress exposure is one pathway through which early neglect could compromise physical health. In contrast, early family care might buffer against these risks. En ligne : http://dx.doi.org/10.1017/s0954579420001479 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=437 [article] The prospective association between stressful life events and inflammation among adolescents with a history of early institutional rearing [Texte imprimé et/ou numérique] / Alva TANG, Auteur ; Mark WADE, Auteur ; Nathan A. FOX, Auteur ; Charles A. NELSON, Auteur ; Charles H. ZEANAH, Auteur ; Natalie SLOPEN, Auteur . - p.1715-1724. Langues : Anglais (eng) in Development and Psychopathology > 32-5 (December 2020) . - p.1715-1724 Mots-clés : Adolescent  Child  *Child, Institutionalized  Child, Preschool  *Foster Home Care  Humans  Infant  Inflammation  Prospective Studies  Romania  *adolescence  *inflammation  *neglect  *stress sensitization  *stressful life events Index. décimale : PER Périodiques Résumé : Early adversity has been shown to sensitize individuals to the effects of later stress and enhance risk of psychopathology. Using a longitudinal randomized trial of foster care as an alternative to institutional care, we extend the stress sensitization hypothesis to examine whether early institutional rearing sensitizes individuals to stressful events in adolescence engendering chronic low-grade inflammation. At baseline, institutionalized children in Romania (ages 6-31 months) were randomly assigned to foster care or to remain in usual care within institutions. A group of never-institutionalized children was recruited as an in-country comparison sample. At ages 12 and 16, participants reported stressful events. At age 16, Interleukin-6 (IL-6) and C-reactive protein (CRP) were derived from blood spots. Among children assigned to care as usual, more stressful events at age 12, but not age 16, were associated with higher IL-6. In the same group, stressful events at age 16 were associated with higher CRP, though these effects attenuated after adjusting for covariates. These associations were not observed in the foster care or never-institutionalized groups. The findings suggest that heightened inflammation following stress exposure is one pathway through which early neglect could compromise physical health. In contrast, early family care might buffer against these risks. En ligne : http://dx.doi.org/10.1017/s0954579420001479 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=437

Early adversity and children's emotion regulation: Differential roles of parent emotion regulation and adversity exposure / Helen M. MILOJEVICH in Development and Psychopathology, 32-5 (December 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-5 (December 2020) . - p.1788-1798 Titre : Early adversity and children's emotion regulation: Differential roles of parent emotion regulation and adversity exposure Type de document : Texte imprimé et/ou numérique Auteurs : Helen M. MILOJEVICH, Auteur ; Laura MACHLIN, Auteur ; Margaret A. SHERIDAN, Auteur Article en page(s) : p.1788-1798 Langues : Anglais (eng) Mots-clés : Child  Child, Preschool  *Emotional Regulation  Emotions  Family  Humans  Parents  *Socialization  *dmap  *abuse  *early adversity  *emotion regulation  *neglect Index. décimale : PER Périodiques Résumé : Exposure to early life adversity (ELA) is associated with increased rates of psychopathology and poor physical health. The present study builds on foundational work by Megan Gunnar identifying how ELA results in poor long-term outcomes through alterations in the stress response system, leading to major disruptions in emotional and behavioral regulation. Specifically, the present study tested the direct effects of ELA against the role of parent socialization to shed light on the mechanisms by which ELA leads to emotion regulation deficits. Children ages 4-7 years (N = 64) completed interviews about their experiences of deprivation and threat, a fear conditioning and extinction paradigm, and an IQ test. Parents of the children completed questionnaires regarding their own emotion regulation difficulties and psychopathology, their children's emotion regulation, and child exposure to adversity. At the bivariate level, greater exposure to threat and parental difficulties with emotion regulation were associated with poorer emotion regulation in children, assessed both via parental report and physiologically. In models where parental difficulties with emotion regulation, threat, and deprivation were introduced simultaneously, regression results indicated that parental difficulties with emotion regulation, but not deprivation or threat, continued to predict children's emotion regulation abilities. These results suggest that parental socialization of emotion is a robust predictor of emotion regulation tendencies in children exposed to early adversity. En ligne : http://dx.doi.org/10.1017/s0954579420001273 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=437 [article] Early adversity and children's emotion regulation: Differential roles of parent emotion regulation and adversity exposure [Texte imprimé et/ou numérique] / Helen M. MILOJEVICH, Auteur ; Laura MACHLIN, Auteur ; Margaret A. SHERIDAN, Auteur . - p.1788-1798. Langues : Anglais (eng) in Development and Psychopathology > 32-5 (December 2020) . - p.1788-1798 Mots-clés : Child  Child, Preschool  *Emotional Regulation  Emotions  Family  Humans  Parents  *Socialization  *dmap  *abuse  *early adversity  *emotion regulation  *neglect Index. décimale : PER Périodiques Résumé : Exposure to early life adversity (ELA) is associated with increased rates of psychopathology and poor physical health. The present study builds on foundational work by Megan Gunnar identifying how ELA results in poor long-term outcomes through alterations in the stress response system, leading to major disruptions in emotional and behavioral regulation. Specifically, the present study tested the direct effects of ELA against the role of parent socialization to shed light on the mechanisms by which ELA leads to emotion regulation deficits. Children ages 4-7 years (N = 64) completed interviews about their experiences of deprivation and threat, a fear conditioning and extinction paradigm, and an IQ test. Parents of the children completed questionnaires regarding their own emotion regulation difficulties and psychopathology, their children's emotion regulation, and child exposure to adversity. At the bivariate level, greater exposure to threat and parental difficulties with emotion regulation were associated with poorer emotion regulation in children, assessed both via parental report and physiologically. In models where parental difficulties with emotion regulation, threat, and deprivation were introduced simultaneously, regression results indicated that parental difficulties with emotion regulation, but not deprivation or threat, continued to predict children's emotion regulation abilities. These results suggest that parental socialization of emotion is a robust predictor of emotion regulation tendencies in children exposed to early adversity. En ligne : http://dx.doi.org/10.1017/s0954579420001273 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=437

Environmental determinants of physiological reactivity to stress: The interacting effects of early life deprivation, caregiving quality, and stressful life events / Mark WADE in Development and Psychopathology, 32-5 (December 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-5 (December 2020) . - p.1732-1742 Titre : Environmental determinants of physiological reactivity to stress: The interacting effects of early life deprivation, caregiving quality, and stressful life events Type de document : Texte imprimé et/ou numérique Auteurs : Mark WADE, Auteur ; Margaret A. SHERIDAN, Auteur ; Charles H. ZEANAH, Auteur ; Nathan A. FOX, Auteur ; Charles A. NELSON, Auteur ; Katie A. MCLAUGHLIN, Auteur Article en page(s) : p.1732-1742 Langues : Anglais (eng) Mots-clés : Adolescent  Child  *Child, Institutionalized  Foster Home Care  Humans  Hydrocortisone  Hypothalamo-Hypophyseal System  *Pituitary-Adrenal System  Psychosocial Deprivation  Stress, Psychological  *HPA-axis  *developmental psychobiology  *institutional rearing  *neglect  *stress reactivity  *sympathetic nervous system Index. décimale : PER Périodiques Résumé : Children who spend their early lives in institutions experience profound psychosocial deprivation that is associated with altered stress response system development. Here, we used data from a longitudinal randomized controlled trial of foster care for institutionally reared children to examine whether caregiving quality and stressful life events (SLEs) in early adolescence (age 12) influence patterns of hypothalamic-pituitary-adrenal (HPA) axis and sympathetic nervous system (SNS) reactivity. Controlling for the effect of institutional care, higher caregiving quality at age 12 was associated with heightened cortisol and SNS reactivity. However, moderation analysis revealed that the latter effect was only observed among never-institutionalized children, whereas ever-institutionalized children demonstrated a persistently blunted SNS response regardless of recent caregiving quality. Among institutionally reared children, SLEs interacted with prior random assignment to foster care, such that those placed in foster care early in development had a SNS response that approximated never-institutionalized children when SLEs at age 12 were low. In contrast, SNS reactivity was persistently blunted among those with prolonged deprivation, regardless of recent SLEs. Early-life deprivation is associated with persistent blunting of stress response systems, but normalization may be achievable if SLEs are limited following placement into enriched family-based care. En ligne : http://dx.doi.org/10.1017/s0954579420001327 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=437 [article] Environmental determinants of physiological reactivity to stress: The interacting effects of early life deprivation, caregiving quality, and stressful life events [Texte imprimé et/ou numérique] / Mark WADE, Auteur ; Margaret A. SHERIDAN, Auteur ; Charles H. ZEANAH, Auteur ; Nathan A. FOX, Auteur ; Charles A. NELSON, Auteur ; Katie A. MCLAUGHLIN, Auteur . - p.1732-1742. Langues : Anglais (eng) in Development and Psychopathology > 32-5 (December 2020) . - p.1732-1742 Mots-clés : Adolescent  Child  *Child, Institutionalized  Foster Home Care  Humans  Hydrocortisone  Hypothalamo-Hypophyseal System  *Pituitary-Adrenal System  Psychosocial Deprivation  Stress, Psychological  *HPA-axis  *developmental psychobiology  *institutional rearing  *neglect  *stress reactivity  *sympathetic nervous system Index. décimale : PER Périodiques Résumé : Children who spend their early lives in institutions experience profound psychosocial deprivation that is associated with altered stress response system development. Here, we used data from a longitudinal randomized controlled trial of foster care for institutionally reared children to examine whether caregiving quality and stressful life events (SLEs) in early adolescence (age 12) influence patterns of hypothalamic-pituitary-adrenal (HPA) axis and sympathetic nervous system (SNS) reactivity. Controlling for the effect of institutional care, higher caregiving quality at age 12 was associated with heightened cortisol and SNS reactivity. However, moderation analysis revealed that the latter effect was only observed among never-institutionalized children, whereas ever-institutionalized children demonstrated a persistently blunted SNS response regardless of recent caregiving quality. Among institutionally reared children, SLEs interacted with prior random assignment to foster care, such that those placed in foster care early in development had a SNS response that approximated never-institutionalized children when SLEs at age 12 were low. In contrast, SNS reactivity was persistently blunted among those with prolonged deprivation, regardless of recent SLEs. Early-life deprivation is associated with persistent blunting of stress response systems, but normalization may be achievable if SLEs are limited following placement into enriched family-based care. En ligne : http://dx.doi.org/10.1017/s0954579420001327 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=437