13 recherche sur le mot-clé 'cohort'

Developmental Trajectories of Adaptive Behaviors from Early Childhood to Adolescence in a Cohort of 152 Children with Autism Spectrum Disorders / Amaria BAGHDADLI in Journal of Autism and Developmental Disorders, 42-7 (July 2012)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 42-7 (July 2012) . - p.1314-1325 Titre : Developmental Trajectories of Adaptive Behaviors from Early Childhood to Adolescence in a Cohort of 152 Children with Autism Spectrum Disorders Type de document : texte imprimé Auteurs : Amaria BAGHDADLI, Auteur ; Brigitte ASSOULINE, Auteur ; Sandrine SONIE, Auteur ; Eric PERNON, Auteur ; Céline DARROU, Auteur ; Cécile MICHELON, Auteur ; Marie-Christine PICOT, Auteur ; Charles AUSSILLOUX, Auteur ; René PRY, Auteur Année de publication : 2012 Article en page(s) : p.1314-1325 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Developmental trajectory  Adaptive behaviors  Cohort Index. décimale : PER Périodiques Résumé : This study examines change in 152 children over an almost 10-year period (T1: 4.9 (±1.3) years; T2: 8.1 (±1.3) years; T3: 15(±1.6) years) using a group-based, semi-parametric method in order to identify distinct developmental trajectories. Important deficits remain at adolescence in the adaptive abilities of children with Autism spectrum disorders, but changes in adaptive skills show two distinct growth rates. The univariate analysis reveals that low growth trajectories for both social and communication outcome are associated with the following characteristics at age 5: low cognitive and language skills, presence of epilepsy, and severity of autism. The multivariate analysis confirms that risk factors at age 5, were low language and severity of autism for both social and communication outcomes 10 years later, and that hours of early intervention was protective factor for communication. En ligne : http://dx.doi.org/10.1007/s10803-011-1357-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=166 [article] Developmental Trajectories of Adaptive Behaviors from Early Childhood to Adolescence in a Cohort of 152 Children with Autism Spectrum Disorders [texte imprimé] / Amaria BAGHDADLI, Auteur ; Brigitte ASSOULINE, Auteur ; Sandrine SONIE, Auteur ; Eric PERNON, Auteur ; Céline DARROU, Auteur ; Cécile MICHELON, Auteur ; Marie-Christine PICOT, Auteur ; Charles AUSSILLOUX, Auteur ; René PRY, Auteur . - 2012 . - p.1314-1325. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 42-7 (July 2012) . - p.1314-1325 Mots-clés : Autism spectrum disorders  Developmental trajectory  Adaptive behaviors  Cohort Index. décimale : PER Périodiques Résumé : This study examines change in 152 children over an almost 10-year period (T1: 4.9 (±1.3) years; T2: 8.1 (±1.3) years; T3: 15(±1.6) years) using a group-based, semi-parametric method in order to identify distinct developmental trajectories. Important deficits remain at adolescence in the adaptive abilities of children with Autism spectrum disorders, but changes in adaptive skills show two distinct growth rates. The univariate analysis reveals that low growth trajectories for both social and communication outcome are associated with the following characteristics at age 5: low cognitive and language skills, presence of epilepsy, and severity of autism. The multivariate analysis confirms that risk factors at age 5, were low language and severity of autism for both social and communication outcomes 10 years later, and that hours of early intervention was protective factor for communication. En ligne : http://dx.doi.org/10.1007/s10803-011-1357-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=166

Fifteen-Year Prospective Follow-Up Study of Adult Outcomes of Autism Spectrum Disorders Among Children Attending Centers in Five Regional Departments in France: The EpiTED Cohort / Amaria BAGHDADLI in Journal of Autism and Developmental Disorders, 49-6 (June 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-6 (June 2019) . - p.2243-2256 Titre : Fifteen-Year Prospective Follow-Up Study of Adult Outcomes of Autism Spectrum Disorders Among Children Attending Centers in Five Regional Departments in France: The EpiTED Cohort Type de document : texte imprimé Auteurs : Amaria BAGHDADLI, Auteur ; Cécile RATTAZ, Auteur ; Cécile MICHELON, Auteur ; Eric PERNON, Auteur ; Kerim M. MUNIR, Auteur Article en page(s) : p.2243-2256 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Cohort  France  Long-term follow-up  Longitudinal Index. décimale : PER Périodiques Résumé : There is limited data on long-term outcome of ASD with co-occurring intellectual disabilities (ID) and challenging behaviours in France. The EpiTED period cohort is a 15 years longitudinal study of the developmental trajectories of 281 children initially recruited at mean age of 5 years. Two contrasted developmental trajectories were identified. Low cognitive level, absence of language, and higher ASD scores at baseline were predictive of low growth at follow-up. As adults the participants were predisposed to persistent co-occurring challenging behaviours as well as underlying ID impacting their ability to function independently. The results underscore the need for development of services and supports for adults with ASD in France who may also have already lacked access to adequate interventions and support services. En ligne : https://dx.doi.org/10.1007/s10803-019-03901-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=400 [article] Fifteen-Year Prospective Follow-Up Study of Adult Outcomes of Autism Spectrum Disorders Among Children Attending Centers in Five Regional Departments in France: The EpiTED Cohort [texte imprimé] / Amaria BAGHDADLI, Auteur ; Cécile RATTAZ, Auteur ; Cécile MICHELON, Auteur ; Eric PERNON, Auteur ; Kerim M. MUNIR, Auteur . - p.2243-2256. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-6 (June 2019) . - p.2243-2256 Mots-clés : Autism spectrum disorders  Cohort  France  Long-term follow-up  Longitudinal Index. décimale : PER Périodiques Résumé : There is limited data on long-term outcome of ASD with co-occurring intellectual disabilities (ID) and challenging behaviours in France. The EpiTED period cohort is a 15 years longitudinal study of the developmental trajectories of 281 children initially recruited at mean age of 5 years. Two contrasted developmental trajectories were identified. Low cognitive level, absence of language, and higher ASD scores at baseline were predictive of low growth at follow-up. As adults the participants were predisposed to persistent co-occurring challenging behaviours as well as underlying ID impacting their ability to function independently. The results underscore the need for development of services and supports for adults with ASD in France who may also have already lacked access to adequate interventions and support services. En ligne : https://dx.doi.org/10.1007/s10803-019-03901-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=400

Health and social characteristics of autistic adults in the UK-wide Adult Autism Spectrum Cohort (ASC-UK): A cross-sectional study / S. BRICE in Research in Autism, 137 (September 2026)  

Public ISBD [article]  inResearch in Autism > 137 (September 2026) . - 202963 Titre : Health and social characteristics of autistic adults in the UK-wide Adult Autism Spectrum Cohort (ASC-UK): A cross-sectional study Type de document : texte imprimé Auteurs : S. BRICE, Auteur ; A. M. PETROU, Auteur ; J. HAMILTON, Auteur ; H. MCCONACHIE, Auteur ; A. LE COUTEUR, Auteur ; B. INGHAM, Auteur ; C. WILSON, Auteur ; R. HARDY, Auteur ; T. BERNEY, Auteur ; D. MASON, Auteur ; D. GARLAND, Auteur ; J. R. PARR, Auteur Article en page(s) : 202963 Langues : Anglais (eng) Mots-clés : Autistic adults  Mental health  Physical health  Social  Cohort Index. décimale : PER Périodiques Résumé : Purpose This study aimed to characterise the health, social, and demographic circumstances of autistic adults in the UK using data from the Adult Autism Spectrum Cohort-UK (ASC-UK), a large, cross-sectional, population-based cohort. It sought to identify age- and gender-related differences in mental and physical health, healthcare access, employment, social relationships, and support needs. Methods Between 2015 and 2021, 2129 autistic adults (diagnosed or self-identified), aged 16 years and older, were recruited via diverse routes including NHS services and community organisations. Data were collected using a 78-item registration questionnaire covering ten domains of daily life and the Social Responsiveness Scale-2 (SRS-2). Responders were grouped into four age categories and compared using appropriate statistical tests including ANOVA, Kruskal-Wallis, Chi-square, and effect size measures. Results Autistic adults reported high rates of physical (e.g., gastrointestinal, obesity, arthritis) and mental health conditions (e.g., anxiety, depression), with notable gender and age variation. Females reported significantly more mental and physical health issues than males. Employment was lowest in the youngest and oldest groups and unemployment was associated with poor mental health. A substantial gap was found between needed and received support, particularly among females and those with complex health needs. Social deprivation was not significantly associated with health diagnoses. Conclusion Autistic adults across the UK experience substantial health disparities and unmet support needs. Gender and age influence outcomes, and healthcare services must adapt to improve access and equity. This study offers critical, lifespan-wide insights to inform policy, practice, and future longitudinal research. En ligne : https://doi.org/10.1016/j.reia.2026.202963 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=592 [article] Health and social characteristics of autistic adults in the UK-wide Adult Autism Spectrum Cohort (ASC-UK): A cross-sectional study [texte imprimé] / S. BRICE, Auteur ; A. M. PETROU, Auteur ; J. HAMILTON, Auteur ; H. MCCONACHIE, Auteur ; A. LE COUTEUR, Auteur ; B. INGHAM, Auteur ; C. WILSON, Auteur ; R. HARDY, Auteur ; T. BERNEY, Auteur ; D. MASON, Auteur ; D. GARLAND, Auteur ; J. R. PARR, Auteur . - 202963. Langues : Anglais (eng) in Research in Autism > 137 (September 2026) . - 202963 Mots-clés : Autistic adults  Mental health  Physical health  Social  Cohort Index. décimale : PER Périodiques Résumé : Purpose This study aimed to characterise the health, social, and demographic circumstances of autistic adults in the UK using data from the Adult Autism Spectrum Cohort-UK (ASC-UK), a large, cross-sectional, population-based cohort. It sought to identify age- and gender-related differences in mental and physical health, healthcare access, employment, social relationships, and support needs. Methods Between 2015 and 2021, 2129 autistic adults (diagnosed or self-identified), aged 16 years and older, were recruited via diverse routes including NHS services and community organisations. Data were collected using a 78-item registration questionnaire covering ten domains of daily life and the Social Responsiveness Scale-2 (SRS-2). Responders were grouped into four age categories and compared using appropriate statistical tests including ANOVA, Kruskal-Wallis, Chi-square, and effect size measures. Results Autistic adults reported high rates of physical (e.g., gastrointestinal, obesity, arthritis) and mental health conditions (e.g., anxiety, depression), with notable gender and age variation. Females reported significantly more mental and physical health issues than males. Employment was lowest in the youngest and oldest groups and unemployment was associated with poor mental health. A substantial gap was found between needed and received support, particularly among females and those with complex health needs. Social deprivation was not significantly associated with health diagnoses. Conclusion Autistic adults across the UK experience substantial health disparities and unmet support needs. Gender and age influence outcomes, and healthcare services must adapt to improve access and equity. This study offers critical, lifespan-wide insights to inform policy, practice, and future longitudinal research. En ligne : https://doi.org/10.1016/j.reia.2026.202963 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=592

Longitudinal change in symptom severity in children with ASD: Results from the ELENA cohort / Florine DELLAPIAZZA in Autism Research, 17-11 (November 2024)  

Public ISBD [article]  inAutism Research > 17-11 (November 2024) . - p.2405-2417 Titre : Longitudinal change in symptom severity in children with ASD: Results from the ELENA cohort Type de document : texte imprimé Auteurs : Florine DELLAPIAZZA, Auteur ; Cécile RATTAZ, Auteur ; Cécile MICHELON, Auteur ; Hugo PEYRE, Auteur ; Marie-Christine PICOT, Auteur ; Amaria BAGHDADLI, Auteur Article en page(s) : p.2405-2417 Langues : Anglais (eng) Mots-clés : ADOS-CSS  autism Spectrum disorders  cohort  follow-up  severity Index. décimale : PER Périodiques Résumé : Abstract Autism spectrum disorder (ASD) is a lifelong neurodevelopmental condition and understanding the changes in autism symptoms over time is crucial for tailoring support and interventions. This study therefore aimed to investigate the changes in symptom severity in a large cohort of children with ASD over a three-year follow-up period and identify factors that influence these changes. The study included 575 children diagnosed with ASD, ranging in age from 2 to 12 years, who were assessed at baseline and again 3 years later using the Autism Diagnostic Observational Schedule-2 (ADOS-2). ASD severity changes were investigated using the ADOS calibrated severity score (CSS) scores for total, social affect (SA) and restricted and repetitive behaviors (RRB). Results highlight four distinct patterns: stable high, stable low, increased, and decreased severity. The ADOS CSS total score changed for half of the sample, reflecting an increase in ASD severity for 21.9% and a decrease for 29.1% of children. For the other half, the ADOS CSS score remained stable, either high (34.4%) or low (14.6%). While the majority of previous studies reported stability in ASD severity, our findings revealed significant variability with frequent improvements in SA symptoms whereas RRBs remained stable or worsened. Our findings also showed that an improvement in SA was associated with the youngest group and early diagnosis. However, no clinical or sociodemographic factors were linked to changes in RRB, emphasizing the necessity for RRB-specific therapies. The third six-year follow-up point of the ongoing ELENA cohort study will map the long-term trajectories of the severity of ASD symptoms and their potential risk factors. En ligne : https://doi.org/10.1002/aur.3242 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542 [article] Longitudinal change in symptom severity in children with ASD: Results from the ELENA cohort [texte imprimé] / Florine DELLAPIAZZA, Auteur ; Cécile RATTAZ, Auteur ; Cécile MICHELON, Auteur ; Hugo PEYRE, Auteur ; Marie-Christine PICOT, Auteur ; Amaria BAGHDADLI, Auteur . - p.2405-2417. Langues : Anglais (eng) in Autism Research > 17-11 (November 2024) . - p.2405-2417 Mots-clés : ADOS-CSS  autism Spectrum disorders  cohort  follow-up  severity Index. décimale : PER Périodiques Résumé : Abstract Autism spectrum disorder (ASD) is a lifelong neurodevelopmental condition and understanding the changes in autism symptoms over time is crucial for tailoring support and interventions. This study therefore aimed to investigate the changes in symptom severity in a large cohort of children with ASD over a three-year follow-up period and identify factors that influence these changes. The study included 575 children diagnosed with ASD, ranging in age from 2 to 12 years, who were assessed at baseline and again 3 years later using the Autism Diagnostic Observational Schedule-2 (ADOS-2). ASD severity changes were investigated using the ADOS calibrated severity score (CSS) scores for total, social affect (SA) and restricted and repetitive behaviors (RRB). Results highlight four distinct patterns: stable high, stable low, increased, and decreased severity. The ADOS CSS total score changed for half of the sample, reflecting an increase in ASD severity for 21.9% and a decrease for 29.1% of children. For the other half, the ADOS CSS score remained stable, either high (34.4%) or low (14.6%). While the majority of previous studies reported stability in ASD severity, our findings revealed significant variability with frequent improvements in SA symptoms whereas RRBs remained stable or worsened. Our findings also showed that an improvement in SA was associated with the youngest group and early diagnosis. However, no clinical or sociodemographic factors were linked to changes in RRB, emphasizing the necessity for RRB-specific therapies. The third six-year follow-up point of the ongoing ELENA cohort study will map the long-term trajectories of the severity of ASD symptoms and their potential risk factors. En ligne : https://doi.org/10.1002/aur.3242 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=542

Quality of Life in Parents of Young Adults with ASD: EpiTED Cohort / Cécile RATTAZ in Journal of Autism and Developmental Disorders, 47-9 (September 2017)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 47-9 (September 2017) . - p.2826-2837 Titre : Quality of Life in Parents of Young Adults with ASD: EpiTED Cohort Type de document : texte imprimé Auteurs : Cécile RATTAZ, Auteur ; Cécile MICHELON, Auteur ; Herbert ROEYERS, Auteur ; Amaria BAGHDADLI, Auteur Article en page(s) : p.2826-2837 Langues : Anglais (eng) Mots-clés : Parental QoL  Autism  Young adult  Cohort Index. décimale : PER Périodiques Résumé : The impact of ASD on parental QOL was evaluated in the EpiTED cohort study at early adulthood. Two-third of parents of young adults with ASD (66.7%) reported that their QoL was at least moderately altered. The perceived impact of ASD on parental QoL was related to the young adults’ level of adaptive skills, as well as to symptom severity and the presence of challenging behaviors, which appeared to be the main risk factor. The study of change between adolescence and early adulthood showed that parents whose children had a decrease in challenging behaviors perceived a decreased impact on their QoL. These results argue for the importance to propose specific interventions to target associated challenging behaviors in ASD. En ligne : https://doi.org/10.1007/s10803-017-3197-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=315 [article] Quality of Life in Parents of Young Adults with ASD: EpiTED Cohort [texte imprimé] / Cécile RATTAZ, Auteur ; Cécile MICHELON, Auteur ; Herbert ROEYERS, Auteur ; Amaria BAGHDADLI, Auteur . - p.2826-2837. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 47-9 (September 2017) . - p.2826-2837 Mots-clés : Parental QoL  Autism  Young adult  Cohort Index. décimale : PER Périodiques Résumé : The impact of ASD on parental QOL was evaluated in the EpiTED cohort study at early adulthood. Two-third of parents of young adults with ASD (66.7%) reported that their QoL was at least moderately altered. The perceived impact of ASD on parental QoL was related to the young adults’ level of adaptive skills, as well as to symptom severity and the presence of challenging behaviors, which appeared to be the main risk factor. The study of change between adolescence and early adulthood showed that parents whose children had a decrease in challenging behaviors perceived a decreased impact on their QoL. These results argue for the importance to propose specific interventions to target associated challenging behaviors in ASD. En ligne : https://doi.org/10.1007/s10803-017-3197-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=315

School Inclusion in Children and Adolescents with Autism Spectrum Disorders in France: Report from the ELENA French Cohort Study / Cécile RATTAZ in Journal of Autism and Developmental Disorders, 50-2 (February 2020)  

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The long-term cost of childhood conduct problems: Finnish Nationwide 1981 Birth Cohort Study / Elisa RISSANEN in Journal of Child Psychology and Psychiatry, 63-6 (June 2022)  

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Covid-19, social restrictions, and mental distress among young people: a UK longitudinal, population-based study / Gemma KNOWLES in Journal of Child Psychology and Psychiatry, 63-11 (November 2022)  

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Developmental trajectories in infants and pre-school children with Neurofibromatosis 1 / Hannah SLEVIN in Molecular Autism, 15 (2024)  

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The relationship between type, timing and duration of exposure to adverse childhood experiences and adolescent self-harm and depression: findings from three UK prospective population-based cohorts / Abigail E. RUSSELL ; Laura D. HOWE ; Annie HERBERT ; Andrew D.A.C. SMITH ; Helen L. FISHER ; Jessie R. BALDWIN ; Louise ARSENEAULT ; Andrea DANESE ; Becky MARS in Journal of Child Psychology and Psychiatry, 65-10 (October 2024)  

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