12 recherche sur le mot-clé 'gastrointestinal symptoms'

Gastrointestinal Symptoms and Oral Antibiotic Use in Children with Autism Spectrum Disorder: Retrospective Analysis of a Privately Insured U.S. Population / T. VARGASON in Journal of Autism and Developmental Disorders, 49-2 (February 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-2 (February 2019) . - p.647-659 Titre : Gastrointestinal Symptoms and Oral Antibiotic Use in Children with Autism Spectrum Disorder: Retrospective Analysis of a Privately Insured U.S. Population Type de document : Texte imprimé et/ou numérique Auteurs : T. VARGASON, Auteur ; D. L. MCGUINNESS, Auteur ; J. HAHN, Auteur Article en page(s) : p.647-659 Langues : Anglais (eng) Mots-clés : Administrative claims  Autism spectrum disorder  Gastrointestinal symptoms  Gut microbiome  Oral antibiotics  Retrospective analysis Index. décimale : PER Périodiques Résumé : A retrospective analysis of administrative claims data from a large U.S. health insurer was performed to study a potential association between oral antibiotic use during early childhood and occurrence of later gastrointestinal (GI) symptoms in children with autism spectrum disorder (ASD). Among 3253 children with ASD, 37.0% had a GI-related diagnosis during the last 2 years of their 5-year health coverage enrollment period, compared to 20.0% of 278,370 children from the general population without an ASD diagnosis. Greater numbers of oral antibiotic fills during the first 3 years of enrollment were found to significantly increase the hazard rate of having a later GI-related diagnosis (adjusted hazard ratio 1.48; 95% confidence interval 1.34, 1.63) in children both with and without ASD. En ligne : http://dx.doi.org/10.1007/s10803-018-3743-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=382 [article] Gastrointestinal Symptoms and Oral Antibiotic Use in Children with Autism Spectrum Disorder: Retrospective Analysis of a Privately Insured U.S. Population [Texte imprimé et/ou numérique] / T. VARGASON, Auteur ; D. L. MCGUINNESS, Auteur ; J. HAHN, Auteur . - p.647-659. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-2 (February 2019) . - p.647-659 Mots-clés : Administrative claims  Autism spectrum disorder  Gastrointestinal symptoms  Gut microbiome  Oral antibiotics  Retrospective analysis Index. décimale : PER Périodiques Résumé : A retrospective analysis of administrative claims data from a large U.S. health insurer was performed to study a potential association between oral antibiotic use during early childhood and occurrence of later gastrointestinal (GI) symptoms in children with autism spectrum disorder (ASD). Among 3253 children with ASD, 37.0% had a GI-related diagnosis during the last 2 years of their 5-year health coverage enrollment period, compared to 20.0% of 278,370 children from the general population without an ASD diagnosis. Greater numbers of oral antibiotic fills during the first 3 years of enrollment were found to significantly increase the hazard rate of having a later GI-related diagnosis (adjusted hazard ratio 1.48; 95% confidence interval 1.34, 1.63) in children both with and without ASD. En ligne : http://dx.doi.org/10.1007/s10803-018-3743-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=382

Gastrointestinal symptoms and sensory abnormalities associated with behavioral problems in children with neurodevelopmental disorders / S. KUROKAWA in Autism Research, 14-9 (September 2021)  

Public ISBD [article]  inAutism Research > 14-9 (September 2021) . - p.1996-2001 Titre : Gastrointestinal symptoms and sensory abnormalities associated with behavioral problems in children with neurodevelopmental disorders Type de document : Texte imprimé et/ou numérique Auteurs : S. KUROKAWA, Auteur ; K. NOMURA, Auteur ; K. MIYAHO, Auteur ; K. SANADA, Auteur ; C. IWAMOTO, Auteur ; M. NARAOKA, Auteur ; S. YONEDA, Auteur ; Y. TOMIZAWA, Auteur ; Y. SAWAE, Auteur ; R. IWANAGA, Auteur ; M. MIMURA, Auteur ; T. KISHIMOTO, Auteur Article en page(s) : p.1996-2001 Langues : Anglais (eng) Mots-clés : Attention Deficit Disorder with Hyperactivity/complications  Autism Spectrum Disorder/complications  Child  Cross-Sectional Studies  Humans  Problem Behavior  Quality of Life  Autism spectrum disorders  attention-deficit/hyperactivity disorder  behavioral problems  gastrointestinal symptoms  sensory abnormalities Index. décimale : PER Périodiques Résumé : Behavioral problems directly affect the quality of life of caregivers and children with autism spectrum disorder (ASD) and/or attention-deficit/hyperactivity disorder (ADHD), and is known to be associated with clinical factors such as gastrointestinal (GI) symptoms, sensory abnormalities, intellectual abilities, and use of medication. However, previous studies have not considered these relationships comprehensively. We conducted a cross-sectional study of 6-12-year-old children with diagnoses of ASD and/or ADHD at two hospitals in Japan. Scores for the aberrant behavior checklist (ABC), autism-spectrum quotient (AQ), and Conners 3, as well as information on daily sleep and exercise, GI symptoms, and Short Sensory Profile, were collected. Each factor was subjected to a correlation analysis to investigate its effect on ABC scores. A stepwise multiple linear regression analysis for the factors with p? En ligne : http://dx.doi.org/10.1002/aur.2549 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450 [article] Gastrointestinal symptoms and sensory abnormalities associated with behavioral problems in children with neurodevelopmental disorders [Texte imprimé et/ou numérique] / S. KUROKAWA, Auteur ; K. NOMURA, Auteur ; K. MIYAHO, Auteur ; K. SANADA, Auteur ; C. IWAMOTO, Auteur ; M. NARAOKA, Auteur ; S. YONEDA, Auteur ; Y. TOMIZAWA, Auteur ; Y. SAWAE, Auteur ; R. IWANAGA, Auteur ; M. MIMURA, Auteur ; T. KISHIMOTO, Auteur . - p.1996-2001. Langues : Anglais (eng) in Autism Research > 14-9 (September 2021) . - p.1996-2001 Mots-clés : Attention Deficit Disorder with Hyperactivity/complications  Autism Spectrum Disorder/complications  Child  Cross-Sectional Studies  Humans  Problem Behavior  Quality of Life  Autism spectrum disorders  attention-deficit/hyperactivity disorder  behavioral problems  gastrointestinal symptoms  sensory abnormalities Index. décimale : PER Périodiques Résumé : Behavioral problems directly affect the quality of life of caregivers and children with autism spectrum disorder (ASD) and/or attention-deficit/hyperactivity disorder (ADHD), and is known to be associated with clinical factors such as gastrointestinal (GI) symptoms, sensory abnormalities, intellectual abilities, and use of medication. However, previous studies have not considered these relationships comprehensively. We conducted a cross-sectional study of 6-12-year-old children with diagnoses of ASD and/or ADHD at two hospitals in Japan. Scores for the aberrant behavior checklist (ABC), autism-spectrum quotient (AQ), and Conners 3, as well as information on daily sleep and exercise, GI symptoms, and Short Sensory Profile, were collected. Each factor was subjected to a correlation analysis to investigate its effect on ABC scores. A stepwise multiple linear regression analysis for the factors with p? En ligne : http://dx.doi.org/10.1002/aur.2549 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450

Affective problems, gastrointestinal symptoms, sleep problems, and challenging behaviour in children and adolescents with autism spectrum disorder / Geraldine LEADER in Research in Autism Spectrum Disorders, 92 (April 2022)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 92 (April 2022) . - 101915 Titre : Affective problems, gastrointestinal symptoms, sleep problems, and challenging behaviour in children and adolescents with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Geraldine LEADER, Auteur ; Hannah BROWNE, Auteur ; Sally WHELAN, Auteur ; Hannah CUMMINS, Auteur ; Arlene MANNION, Auteur Article en page(s) : 101915 Langues : Anglais (eng) Mots-clés : Autism  Affective problems  Sleep problems  Challenging behaviour  Gastrointestinal symptoms Index. décimale : PER Périodiques Résumé : Background People with autism spectrum disorder (ASD) can experience affective problems, gastrointestinal (GI) symptoms, sleep problems, and challenging behaviour. This study identified the frequency of affective problems and explored how they related to co-occurring conditions in children and adolescents with ASD. Method Participants were children and adolescents diagnosed with ASD using DSM-IV-TR criteria (n = 95), 40 % (n = 38) of whom also had a diagnosis of intellectual disability (ID). The following scales were completed by the participants’ parents or guardians: Child Behaviour Checklist (CBCL), Gastrointestinal Symptoms Inventory, Children’s Sleep Habits Questionnaire (CSHQ), and the Behaviour Problems Inventory-Short Form (BPI-S). Pearson’s correlations and independent sample t-tests were used to examine the relationships between variables. Two hierarchal multiple regressions examined predictors for affective problems in preschool and school-aged children with ASD. Results Participants scored in the clinical range (69.5 %) and borderline range (10.5 %) for affective problems. Significant positive relationships were found between affective problems and sleep problems, GI symptoms, and challenging behaviour. ID and gender predicted affective problems in preschool aged children. In school-aged children, affective problems were predicted by ID, sleep problems, and aggressive/destructive behaviour severity. However, only 25 % of the variance in affective problems was accounted for. Conclusions Future research is needed to understand how affective problems are impacted by co-occurring conditions in children and adolescents with ASD. Affective problems are prevalent in this population and the quality of life for individuals may be improved if practitioners consider co-occurring conditions during clinical practice. En ligne : https://doi.org/10.1016/j.rasd.2022.101915 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=458 [article] Affective problems, gastrointestinal symptoms, sleep problems, and challenging behaviour in children and adolescents with autism spectrum disorder [Texte imprimé et/ou numérique] / Geraldine LEADER, Auteur ; Hannah BROWNE, Auteur ; Sally WHELAN, Auteur ; Hannah CUMMINS, Auteur ; Arlene MANNION, Auteur . - 101915. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 92 (April 2022) . - 101915 Mots-clés : Autism  Affective problems  Sleep problems  Challenging behaviour  Gastrointestinal symptoms Index. décimale : PER Périodiques Résumé : Background People with autism spectrum disorder (ASD) can experience affective problems, gastrointestinal (GI) symptoms, sleep problems, and challenging behaviour. This study identified the frequency of affective problems and explored how they related to co-occurring conditions in children and adolescents with ASD. Method Participants were children and adolescents diagnosed with ASD using DSM-IV-TR criteria (n = 95), 40 % (n = 38) of whom also had a diagnosis of intellectual disability (ID). The following scales were completed by the participants’ parents or guardians: Child Behaviour Checklist (CBCL), Gastrointestinal Symptoms Inventory, Children’s Sleep Habits Questionnaire (CSHQ), and the Behaviour Problems Inventory-Short Form (BPI-S). Pearson’s correlations and independent sample t-tests were used to examine the relationships between variables. Two hierarchal multiple regressions examined predictors for affective problems in preschool and school-aged children with ASD. Results Participants scored in the clinical range (69.5 %) and borderline range (10.5 %) for affective problems. Significant positive relationships were found between affective problems and sleep problems, GI symptoms, and challenging behaviour. ID and gender predicted affective problems in preschool aged children. In school-aged children, affective problems were predicted by ID, sleep problems, and aggressive/destructive behaviour severity. However, only 25 % of the variance in affective problems was accounted for. Conclusions Future research is needed to understand how affective problems are impacted by co-occurring conditions in children and adolescents with ASD. Affective problems are prevalent in this population and the quality of life for individuals may be improved if practitioners consider co-occurring conditions during clinical practice. En ligne : https://doi.org/10.1016/j.rasd.2022.101915 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=458

An analysis of the predictors of comorbid psychopathology, gastrointestinal symptoms and epilepsy in children and adolescents with autism spectrum disorder / Arlene MANNION in Research in Autism Spectrum Disorders, 7-12 (December 2013)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 7-12 (December 2013) . - p.1663-1671 Titre : An analysis of the predictors of comorbid psychopathology, gastrointestinal symptoms and epilepsy in children and adolescents with autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Arlene MANNION, Auteur ; Geraldine LEADER, Auteur Article en page(s) : p.1663-1671 Langues : Anglais (eng) Mots-clés : Comorbidity  Autism spectrum disorder  Comorbid psychopathology  Sleep problems  Gastrointestinal symptoms Index. décimale : PER Périodiques Résumé : Abstract Mannion, Leader, and Healy (2013) examined the frequency of comorbid disorders in children and adolescents with autism spectrum disorder and the predictors of sleep problems. This study will extend this research by investigating the predictors of comorbidity in 89 participants. Age, gender, level of intellectual disability, presence of epilepsy, attention deficit/hyperactivity disorder (AD/HD) and an anxiety disorder were determined using a self-constructed demographic questionnaire. The Autism Spectrum Disorder-Comorbid for Children (ASD-CC) was administered to informants to assess symptoms of comorbid psychopathology. The Children's Sleep Habits Questionnaire (CSHQ) and Gastrointestinal symptom inventory were administered to assess sleep problems and gastrointestinal symptoms respectively. Sleep problems predicted gastrointestinal symptoms. Level of intellectual disability predicted gastrointestinal symptoms. Specifically, those with no intellectual disability were more likely to present with gastrointestinal symptoms. Gastrointestinal symptoms in turn predicted total comorbid psychopathology score and the individual subscales of worry/depressed, avoidant behavior, conduct behavior and tantrum behavior on the ASD-CC. Gender and ASD-CC total score predicted an individual having an anxiety disorder. Specifically, being male predicted an anxiety disorder. The ASD-CC subscales of worry/depressed and avoidant behavior predicted an anxiety disorder. The implications of these findings are discussed in the study. En ligne : http://dx.doi.org/10.1016/j.rasd.2013.10.002 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=219 [article] An analysis of the predictors of comorbid psychopathology, gastrointestinal symptoms and epilepsy in children and adolescents with autism spectrum disorder [Texte imprimé et/ou numérique] / Arlene MANNION, Auteur ; Geraldine LEADER, Auteur . - p.1663-1671. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 7-12 (December 2013) . - p.1663-1671 Mots-clés : Comorbidity  Autism spectrum disorder  Comorbid psychopathology  Sleep problems  Gastrointestinal symptoms Index. décimale : PER Périodiques Résumé : Abstract Mannion, Leader, and Healy (2013) examined the frequency of comorbid disorders in children and adolescents with autism spectrum disorder and the predictors of sleep problems. This study will extend this research by investigating the predictors of comorbidity in 89 participants. Age, gender, level of intellectual disability, presence of epilepsy, attention deficit/hyperactivity disorder (AD/HD) and an anxiety disorder were determined using a self-constructed demographic questionnaire. The Autism Spectrum Disorder-Comorbid for Children (ASD-CC) was administered to informants to assess symptoms of comorbid psychopathology. The Children's Sleep Habits Questionnaire (CSHQ) and Gastrointestinal symptom inventory were administered to assess sleep problems and gastrointestinal symptoms respectively. Sleep problems predicted gastrointestinal symptoms. Level of intellectual disability predicted gastrointestinal symptoms. Specifically, those with no intellectual disability were more likely to present with gastrointestinal symptoms. Gastrointestinal symptoms in turn predicted total comorbid psychopathology score and the individual subscales of worry/depressed, avoidant behavior, conduct behavior and tantrum behavior on the ASD-CC. Gender and ASD-CC total score predicted an individual having an anxiety disorder. Specifically, being male predicted an anxiety disorder. The ASD-CC subscales of worry/depressed and avoidant behavior predicted an anxiety disorder. The implications of these findings are discussed in the study. En ligne : http://dx.doi.org/10.1016/j.rasd.2013.10.002 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=219

An investigation of comorbid psychological disorders, sleep problems, gastrointestinal symptoms and epilepsy in children and adolescents with autism spectrum disorder: A two year follow-up / Arlene MANNION in Research in Autism Spectrum Disorders, 22 (February 2016)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 22 (February 2016) . - p.20-33 Titre : An investigation of comorbid psychological disorders, sleep problems, gastrointestinal symptoms and epilepsy in children and adolescents with autism spectrum disorder: A two year follow-up Type de document : Texte imprimé et/ou numérique Auteurs : Arlene MANNION, Auteur ; Geraldine LEADER, Auteur Article en page(s) : p.20-33 Langues : Anglais (eng) Mots-clés : Comorbidity  Autism spectrum disorder  Follow-up  Comorbid psychopathology  Sleep problems  Gastrointestinal symptoms  Autoimmune diseases  Epilepsy Index. décimale : PER Périodiques Résumé : Research has recently focused on studying comorbidity in the autism spectrum but little research has been conducted on follow-up studies or conducting longitudinal research into these conditions. Mannion, Leader, and Healy (2013) examined the frequency of comorbid disorders in children and adolescents with autism spectrum disorder and the predictors of sleep problems. The current study is a follow-up study conducted two years later with 56 participants. Age, gender, level of intellectual disability, presence of epilepsy, attention deficit/hyperactivity disorder (AD/HD) and an anxiety disorder were assessed, along with administering the Autism Spectrum Disorder-Comorbid for Children (ASD-CC), the Children’s Sleep Habits Questionnaire (CSHQ) and Gastrointestinal Symptom Inventory. The aim of the study was to determine if comorbid symptoms changed over time. An additional aim was to explore if there is a relationship between family medical history and history of autoimmune diseases, and child comorbid conditions. Sleep problems persisted in 91.5% of participants. Gastrointestinal symptoms persisted in 84.4% of participants. There was a significant difference between over-eating at baseline and at two-year follow-up, where over-eating became more severe over time. It was found that 92.9% of participants presented with a family history of autoimmune disease. The most common autoimmune diseases were osteoarthritis, psoriasis and hypothyroidism. The associations between familial autoimmune diseases and child comorbid conditions are discussed in the study. En ligne : http://dx.doi.org/10.1016/j.rasd.2015.11.002 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278 [article] An investigation of comorbid psychological disorders, sleep problems, gastrointestinal symptoms and epilepsy in children and adolescents with autism spectrum disorder: A two year follow-up [Texte imprimé et/ou numérique] / Arlene MANNION, Auteur ; Geraldine LEADER, Auteur . - p.20-33. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 22 (February 2016) . - p.20-33 Mots-clés : Comorbidity  Autism spectrum disorder  Follow-up  Comorbid psychopathology  Sleep problems  Gastrointestinal symptoms  Autoimmune diseases  Epilepsy Index. décimale : PER Périodiques Résumé : Research has recently focused on studying comorbidity in the autism spectrum but little research has been conducted on follow-up studies or conducting longitudinal research into these conditions. Mannion, Leader, and Healy (2013) examined the frequency of comorbid disorders in children and adolescents with autism spectrum disorder and the predictors of sleep problems. The current study is a follow-up study conducted two years later with 56 participants. Age, gender, level of intellectual disability, presence of epilepsy, attention deficit/hyperactivity disorder (AD/HD) and an anxiety disorder were assessed, along with administering the Autism Spectrum Disorder-Comorbid for Children (ASD-CC), the Children’s Sleep Habits Questionnaire (CSHQ) and Gastrointestinal Symptom Inventory. The aim of the study was to determine if comorbid symptoms changed over time. An additional aim was to explore if there is a relationship between family medical history and history of autoimmune diseases, and child comorbid conditions. Sleep problems persisted in 91.5% of participants. Gastrointestinal symptoms persisted in 84.4% of participants. There was a significant difference between over-eating at baseline and at two-year follow-up, where over-eating became more severe over time. It was found that 92.9% of participants presented with a family history of autoimmune disease. The most common autoimmune diseases were osteoarthritis, psoriasis and hypothyroidism. The associations between familial autoimmune diseases and child comorbid conditions are discussed in the study. En ligne : http://dx.doi.org/10.1016/j.rasd.2015.11.002 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278

Feeding Problems, Gastrointestinal Symptoms, Challenging Behavior and Sensory Issues in Children and Adolescents with Autism Spectrum Disorder / Geraldine LEADER in Journal of Autism and Developmental Disorders, 50-4 (April 2020)  

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Gastrointestinal dysfunction in patients and mice expressing the autism-associated R451C mutation in neuroligin-3 / S. HOSIE in Autism Research, 12-7 (July 2019)  

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Colonic dilation and altered ex vivo gastrointestinal motility in the neuroligin-3 knockout mouse / Anita J. L. LEEMBRUGGEN in Autism Research, 13-5 (May 2020)  

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An investigation of anxiety in children and adolescents with autism spectrum disorder / Sian WILLIAMS in Research in Autism Spectrum Disorders, 10 (February 2015)  

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Bone Mineral Density in Boys Diagnosed with Autism Spectrum Disorder: A Case-Control Study / K. BARNHILL in Journal of Autism and Developmental Disorders, 47-11 (November 2017)  

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