Brief Report: A Novel System to Evaluate Autism Spectrum Disorders Using Two Humanoid Robots / H. KUMAZAKI in Journal of Autism and Developmental Disorders, 49-4 (April 2019)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 49-4 (April 2019) . - p.1709-1716 Titre : Brief Report: A Novel System to Evaluate Autism Spectrum Disorders Using Two Humanoid Robots Type de document : Texte imprimé et/ou numérique Auteurs : H. KUMAZAKI, Auteur ; T. MURAMATSU, Auteur ; Y. YOSHIKAWA, Auteur ; Y. YOSHIMURA, Auteur ; T. IKEDA, Auteur ; C. HASEGAWA, Auteur ; Daisuke N. SAITO, Auteur ; J. SHIMAYA, Auteur ; H. ISHIGURO, Auteur ; M. MIMURA, Auteur ; M. KIKUCHI, Auteur Article en page(s) : p.1709-1716 Langues : Anglais (eng) Mots-clés : Ados  Autism spectrum disorders  Robot  Severity  Social communication  Typical development Index. décimale : PER Périodiques Résumé : We investigated the feasibility of our novel evaluation system for use with children with autism spectrum disorders (ASD). We prepared the experimental setting with two humanoid robots in reference to the birthday party scene in the Autism Diagnostic Observational Schedule (ADOS). We assessed the relationship between social communication ability measured in the ADOS condition (i.e., with a human clinician) and in a robotic condition for children with ASD. There were significant correlations between the social communication scores in the gold-standard ADOS condition and the robotic condition for children with ASD. The current work provides support for a unique application of a robotic system (i.e., two robot-mediated interaction) to evaluate the severity of autistic traits for children with ASD. En ligne : https://dx.doi.org/10.1007/s10803-018-3848-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=388 [article] Brief Report: A Novel System to Evaluate Autism Spectrum Disorders Using Two Humanoid Robots [Texte imprimé et/ou numérique] / H. KUMAZAKI, Auteur ; T. MURAMATSU, Auteur ; Y. YOSHIKAWA, Auteur ; Y. YOSHIMURA, Auteur ; T. IKEDA, Auteur ; C. HASEGAWA, Auteur ; Daisuke N. SAITO, Auteur ; J. SHIMAYA, Auteur ; H. ISHIGURO, Auteur ; M. MIMURA, Auteur ; M. KIKUCHI, Auteur . - p.1709-1716. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 49-4 (April 2019) . - p.1709-1716 Mots-clés : Ados  Autism spectrum disorders  Robot  Severity  Social communication  Typical development Index. décimale : PER Périodiques Résumé : We investigated the feasibility of our novel evaluation system for use with children with autism spectrum disorders (ASD). We prepared the experimental setting with two humanoid robots in reference to the birthday party scene in the Autism Diagnostic Observational Schedule (ADOS). We assessed the relationship between social communication ability measured in the ADOS condition (i.e., with a human clinician) and in a robotic condition for children with ASD. There were significant correlations between the social communication scores in the gold-standard ADOS condition and the robotic condition for children with ASD. The current work provides support for a unique application of a robotic system (i.e., two robot-mediated interaction) to evaluate the severity of autistic traits for children with ASD. En ligne : https://dx.doi.org/10.1007/s10803-018-3848-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=388

Brief Report: Odour Awareness in Young Children with Autism Spectrum Disorders / Hirokazu KUMAZAKI in Journal of Autism and Developmental Disorders, 50-5 (May 2020)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 50-5 (May 2020) . - p.1809-1815 Titre : Brief Report: Odour Awareness in Young Children with Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Hirokazu KUMAZAKI, Auteur ; Masako OKAMOTO, Auteur ; Yuko YOSHIMURA, Auteur ; Takashi IKEDA, Auteur ; Chiaki HASEGAWA, Auteur ; Daisuke N. SAITO, Auteur ; Ryoichiro IWANAGA, Auteur ; Sara TOMIYAMA, Auteur ; Kyung-Min AN, Auteur ; Yoshio MINABE, Auteur ; Mitsuru KIKUCHI, Auteur Article en page(s) : p.1809-1815 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Odour awareness  Olfactory  Self-report  Vabs ii Index. décimale : PER Périodiques Résumé : The elucidation of odour awareness in children with autism spectrum disorders (ASD) is important. We compared the odour awareness of young children with ASD with those of typical development (TD) children using the Children's Olfactory Behavior in Everyday Life (COBEL) questionnaire, which is a self-report measure that mainly assesses odour awareness. Forty-five young boys (aged 5-6 years), including 20 children with ASD and 25 TD children, participated in this study. The total COBEL score of the young children with ASD was lower than that of the TD children (p < 0.01). Moreover, the total COBEL score was significantly correlated with the total VABS II score (p < 0.05). Our results improve understanding of the odour awareness in children with ASD. En ligne : http://dx.doi.org/10.1007/s10803-018-3710-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=422 [article] Brief Report: Odour Awareness in Young Children with Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Hirokazu KUMAZAKI, Auteur ; Masako OKAMOTO, Auteur ; Yuko YOSHIMURA, Auteur ; Takashi IKEDA, Auteur ; Chiaki HASEGAWA, Auteur ; Daisuke N. SAITO, Auteur ; Ryoichiro IWANAGA, Auteur ; Sara TOMIYAMA, Auteur ; Kyung-Min AN, Auteur ; Yoshio MINABE, Auteur ; Mitsuru KIKUCHI, Auteur . - p.1809-1815. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 50-5 (May 2020) . - p.1809-1815 Mots-clés : Autism spectrum disorders  Odour awareness  Olfactory  Self-report  Vabs ii Index. décimale : PER Périodiques Résumé : The elucidation of odour awareness in children with autism spectrum disorders (ASD) is important. We compared the odour awareness of young children with ASD with those of typical development (TD) children using the Children's Olfactory Behavior in Everyday Life (COBEL) questionnaire, which is a self-report measure that mainly assesses odour awareness. Forty-five young boys (aged 5-6 years), including 20 children with ASD and 25 TD children, participated in this study. The total COBEL score of the young children with ASD was lower than that of the TD children (p < 0.01). Moreover, the total COBEL score was significantly correlated with the total VABS II score (p < 0.05). Our results improve understanding of the odour awareness in children with ASD. En ligne : http://dx.doi.org/10.1007/s10803-018-3710-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=422

Default mode network in young male adults with autism spectrum disorder: relationship with autism spectrum traits / Minyoung JUNG in Molecular Autism, (June 2014)  

Public ISBD [article]  inMolecular Autism > (June 2014) . - p.1-11 Titre : Default mode network in young male adults with autism spectrum disorder: relationship with autism spectrum traits Type de document : Texte imprimé et/ou numérique Auteurs : Minyoung JUNG, Auteur ; Hirotaka KOSAKA, Auteur ; Daisuke N. SAITO, Auteur ; Makoto ISHITOBI, Auteur ; Tomoyo MORITA, Auteur ; Keisuke INOHARA, Auteur ; Mizuki ASANO, Auteur ; Sumiyoshi ARAI, Auteur ; Toshio MUNESUE, Auteur ; Akemi TOMODA, Auteur ; Yuji WADA, Auteur ; Norihiro SADATO, Auteur ; Hidehiko OKAZAWA, Auteur ; Tetsuya IIDAKA, Auteur Article en page(s) : p.1-11 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Autism spectrum traits are postulated to lie on a continuum that extends between individuals with autism and individuals with typical development (TD). Social cognition properties that are deeply associated with autism spectrum traits have been linked to functional connectivity between regions within the brain’s default mode network (DMN). Previous studies have shown that the resting-state functional connectivities (rs-FCs) of DMN are low and show negative correlation with the level of autism spectrum traits in individuals with autism spectrum disorder (ASD). However, it is unclear whether individual differences of autism spectrum traits are associated with the strength of rs-FCs of DMN in participants including the general population. En ligne : http://dx.doi.org/10.1186/2040-2392-5-35 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=276 [article] Default mode network in young male adults with autism spectrum disorder: relationship with autism spectrum traits [Texte imprimé et/ou numérique] / Minyoung JUNG, Auteur ; Hirotaka KOSAKA, Auteur ; Daisuke N. SAITO, Auteur ; Makoto ISHITOBI, Auteur ; Tomoyo MORITA, Auteur ; Keisuke INOHARA, Auteur ; Mizuki ASANO, Auteur ; Sumiyoshi ARAI, Auteur ; Toshio MUNESUE, Auteur ; Akemi TOMODA, Auteur ; Yuji WADA, Auteur ; Norihiro SADATO, Auteur ; Hidehiko OKAZAWA, Auteur ; Tetsuya IIDAKA, Auteur . - p.1-11. Langues : Anglais (eng) in Molecular Autism > (June 2014) . - p.1-11 Index. décimale : PER Périodiques Résumé : Autism spectrum traits are postulated to lie on a continuum that extends between individuals with autism and individuals with typical development (TD). Social cognition properties that are deeply associated with autism spectrum traits have been linked to functional connectivity between regions within the brain’s default mode network (DMN). Previous studies have shown that the resting-state functional connectivities (rs-FCs) of DMN are low and show negative correlation with the level of autism spectrum traits in individuals with autism spectrum disorder (ASD). However, it is unclear whether individual differences of autism spectrum traits are associated with the strength of rs-FCs of DMN in participants including the general population. En ligne : http://dx.doi.org/10.1186/2040-2392-5-35 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=276

Episodic memory retrieval for story characters in high-functioning autism / Hidetsugu KOMEDA in Molecular Autism, (June 2013)  

Public ISBD [article]  inMolecular Autism > (June 2013) . - 9 p. Titre : Episodic memory retrieval for story characters in high-functioning autism Type de document : Texte imprimé et/ou numérique Auteurs : Hidetsugu KOMEDA, Auteur ; Hirotaka KOSAKA, Auteur ; Daisuke N. SAITO, Auteur ; Keisuke INOHARA, Auteur ; Toshio MUNESUE, Auteur ; Makoto ISHITOBI, Auteur ; Makoto SATO, Auteur ; Hidehiko OKAZAWA, Auteur Année de publication : 2013 Article en page(s) : 9 p. Langues : Anglais (eng) Mots-clés : High-functioning autism  Narrative comprehension  Recognition  Memory retrieval  Similarity Index. décimale : PER Périodiques Résumé : Background The objective of this study was to examine differences in episodic memory retrieval between individuals with autism spectrum disorder (ASD) and typically developing (TD) individuals. Previous studies have shown that personality similarities between readers and characters facilitated reading comprehension. Highly extraverted participants read stories featuring extraverted protagonists more easily and judged the outcomes of such stories more rapidly than did less extraverted participants. Similarly, highly neurotic participants judged the outcomes of stories with neurotic protagonists more rapidly than did participants with low levels of neuroticism. However, the impact of the similarity effect on memory retrieval remains unclear. This study tested our ‘similarity hypothesis’, namely that memory retrieval is enhanced when readers with ASD and TD readers read stories featuring protagonists with ASD and with characteristics associated with TD individuals, respectively. Methods Eighteen Japanese individuals (one female) with high-functioning ASD (aged 17 to 40 years) and 17 age- and intelligence quotient (IQ)-matched Japanese (one female) TD participants (aged 22 to 40 years) read 24 stories; 12 stories featured protagonists with ASD characteristics, and the other 12 featured TD protagonists. Participants read a single sentence at a time and pressed a spacebar to advance to the next sentence. After reading all 24 stories, they were asked to complete a recognition task about the target sentence in each story. Results To investigate episodic memory in ASD, we analyzed encoding based on the reading times for and readability of the stories and retrieval processes based on the accuracy of and response times for sentence recognition. Although the results showed no differences between ASD and TD groups in encoding processes, they did reveal inter-group differences in memory retrieval. Although individuals with ASD demonstrated the same level of accuracy as did TD individuals, their patterns of memory retrieval differed with respect to response times. Conclusions Individuals with ASD more effectively retrieved ASD-congruent than ASD-incongruent sentences, and TD individuals retrieved stories with TD more effectively than stories with ASD protagonists. Thus, similarity between reader and story character had different effects on memory retrieval in the ASD and TD groups. En ligne : http://dx.doi.org/10.1186/2040-2392-4-20 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=211 [article] Episodic memory retrieval for story characters in high-functioning autism [Texte imprimé et/ou numérique] / Hidetsugu KOMEDA, Auteur ; Hirotaka KOSAKA, Auteur ; Daisuke N. SAITO, Auteur ; Keisuke INOHARA, Auteur ; Toshio MUNESUE, Auteur ; Makoto ISHITOBI, Auteur ; Makoto SATO, Auteur ; Hidehiko OKAZAWA, Auteur . - 2013 . - 9 p. Langues : Anglais (eng) in Molecular Autism > (June 2013) . - 9 p. Mots-clés : High-functioning autism  Narrative comprehension  Recognition  Memory retrieval  Similarity Index. décimale : PER Périodiques Résumé : Background The objective of this study was to examine differences in episodic memory retrieval between individuals with autism spectrum disorder (ASD) and typically developing (TD) individuals. Previous studies have shown that personality similarities between readers and characters facilitated reading comprehension. Highly extraverted participants read stories featuring extraverted protagonists more easily and judged the outcomes of such stories more rapidly than did less extraverted participants. Similarly, highly neurotic participants judged the outcomes of stories with neurotic protagonists more rapidly than did participants with low levels of neuroticism. However, the impact of the similarity effect on memory retrieval remains unclear. This study tested our ‘similarity hypothesis’, namely that memory retrieval is enhanced when readers with ASD and TD readers read stories featuring protagonists with ASD and with characteristics associated with TD individuals, respectively. Methods Eighteen Japanese individuals (one female) with high-functioning ASD (aged 17 to 40 years) and 17 age- and intelligence quotient (IQ)-matched Japanese (one female) TD participants (aged 22 to 40 years) read 24 stories; 12 stories featured protagonists with ASD characteristics, and the other 12 featured TD protagonists. Participants read a single sentence at a time and pressed a spacebar to advance to the next sentence. After reading all 24 stories, they were asked to complete a recognition task about the target sentence in each story. Results To investigate episodic memory in ASD, we analyzed encoding based on the reading times for and readability of the stories and retrieval processes based on the accuracy of and response times for sentence recognition. Although the results showed no differences between ASD and TD groups in encoding processes, they did reveal inter-group differences in memory retrieval. Although individuals with ASD demonstrated the same level of accuracy as did TD individuals, their patterns of memory retrieval differed with respect to response times. Conclusions Individuals with ASD more effectively retrieved ASD-congruent than ASD-incongruent sentences, and TD individuals retrieved stories with TD more effectively than stories with ASD protagonists. Thus, similarity between reader and story character had different effects on memory retrieval in the ASD and TD groups. En ligne : http://dx.doi.org/10.1186/2040-2392-4-20 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=211

Gazefinder as a clinical supplementary tool for discriminating between autism spectrum disorder and typical development in male adolescents and adults / T. FUJIOKA in Molecular Autism, 7 (2016)  

Public ISBD [article]  inMolecular Autism > 7 (2016) . - 19p. Titre : Gazefinder as a clinical supplementary tool for discriminating between autism spectrum disorder and typical development in male adolescents and adults Type de document : Texte imprimé et/ou numérique Auteurs : T. FUJIOKA, Auteur ; K. INOHARA, Auteur ; Y. OKAMOTO, Auteur ; Y. MASUYA, Auteur ; M. ISHITOBI, Auteur ; Daisuke N. SAITO, Auteur ; M. JUNG, Auteur ; Sumiyoshi ARAI, Auteur ; Y. MATSUMURA, Auteur ; T. X. FUJISAWA, Auteur ; K. NARITA, Auteur ; K. SUZUKI, Auteur ; K. J. TSUCHIYA, Auteur ; N. MORI, Auteur ; T. KATAYAMA, Auteur ; M. SATO, Auteur ; T. MUNESUE, Auteur ; H. OKAZAWA, Auteur ; A. TOMODA, Auteur ; Y. WADA, Auteur ; H. KOSAKA, Auteur Article en page(s) : 19p. Langues : Anglais (eng) Mots-clés : Adolescent  Adult  Area Under Curve  Autism Spectrum Disorder/diagnosis/physiopathology  Case-Control Studies  Discriminant Analysis  Fixation, Ocular/physiology  Humans  Male  Ocular Physiological Phenomena  Photic Stimulation  Psychometrics  ROC Curve  Social Behavior  Time Factors  Autism spectrum disorder  Biological motion  Eye-tracking  Face  Fixation  Gaze abnormality  Geometry Index. décimale : PER Périodiques Résumé : BACKGROUND: Gaze abnormality is a diagnostic criterion for autism spectrum disorder (ASD). However, few easy-to-use clinical tools exist to evaluate the unique eye-gaze patterns of ASD. Recently, we developed Gazefinder, an all-in-one eye-tracking system for early detection of ASD in toddlers. Because abnormal gaze patterns have been documented in various ASD age groups, we predicted that Gazefinder might also detect gaze abnormality in adolescents and adults. In this study, we tested whether Gazefinder could identify unique gaze patterns in adolescents and adults with ASD. METHODS: We measured the percentage of eye fixation time allocated to particular objects depicted in movies (i.e., eyes and mouth in human face movies, upright and inverted biological motion in movies that presented these stimuli simultaneously, and people and geometry in movies that presented these stimuli simultaneously) by male adolescents and adults with ASD (N = 26) and age-matched males with typical development (TD; N = 35). We compared these percentages between the two groups (ASD and TD) and with scores on the social responsiveness scale (SRS). Further, we conducted discriminant analyses to determine if fixation times allocated to particular objects could be used to discriminate between individuals with and without ASD. RESULTS: Compared with the TD group, the ASD group showed significantly less fixation time at locations of salient social information (i.e., eyes in the movie of human faces without lip movement and people in the movie of people and geometry), while there were no significant groupwise differences in the responses to movies of human faces with lip movement or biological motion. In a within-group correlation analysis, a few of the fixation-time items correlated with SRS, although most of them did not. No items significantly correlated with SRS in both ASD and TD groups. The percentage fixation times to eyes and people, which exhibited large effect sizes for the group difference, could differentiate ASD and TD with a sensitivity of 81.0% and a specificity of 80.0%. CONCLUSIONS: These findings suggest that Gazefinder is potentially a valuable and easy-to-use tool for objectively measuring unique gaze patterns and discriminating between ASD and TD in male adolescents and adults. En ligne : http://dx.doi.org/10.1186/s13229-016-0083-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=328 [article] Gazefinder as a clinical supplementary tool for discriminating between autism spectrum disorder and typical development in male adolescents and adults [Texte imprimé et/ou numérique] / T. FUJIOKA, Auteur ; K. INOHARA, Auteur ; Y. OKAMOTO, Auteur ; Y. MASUYA, Auteur ; M. ISHITOBI, Auteur ; Daisuke N. SAITO, Auteur ; M. JUNG, Auteur ; Sumiyoshi ARAI, Auteur ; Y. MATSUMURA, Auteur ; T. X. FUJISAWA, Auteur ; K. NARITA, Auteur ; K. SUZUKI, Auteur ; K. J. TSUCHIYA, Auteur ; N. MORI, Auteur ; T. KATAYAMA, Auteur ; M. SATO, Auteur ; T. MUNESUE, Auteur ; H. OKAZAWA, Auteur ; A. TOMODA, Auteur ; Y. WADA, Auteur ; H. KOSAKA, Auteur . - 19p. Langues : Anglais (eng) in Molecular Autism > 7 (2016) . - 19p. Mots-clés : Adolescent  Adult  Area Under Curve  Autism Spectrum Disorder/diagnosis/physiopathology  Case-Control Studies  Discriminant Analysis  Fixation, Ocular/physiology  Humans  Male  Ocular Physiological Phenomena  Photic Stimulation  Psychometrics  ROC Curve  Social Behavior  Time Factors  Autism spectrum disorder  Biological motion  Eye-tracking  Face  Fixation  Gaze abnormality  Geometry Index. décimale : PER Périodiques Résumé : BACKGROUND: Gaze abnormality is a diagnostic criterion for autism spectrum disorder (ASD). However, few easy-to-use clinical tools exist to evaluate the unique eye-gaze patterns of ASD. Recently, we developed Gazefinder, an all-in-one eye-tracking system for early detection of ASD in toddlers. Because abnormal gaze patterns have been documented in various ASD age groups, we predicted that Gazefinder might also detect gaze abnormality in adolescents and adults. In this study, we tested whether Gazefinder could identify unique gaze patterns in adolescents and adults with ASD. METHODS: We measured the percentage of eye fixation time allocated to particular objects depicted in movies (i.e., eyes and mouth in human face movies, upright and inverted biological motion in movies that presented these stimuli simultaneously, and people and geometry in movies that presented these stimuli simultaneously) by male adolescents and adults with ASD (N = 26) and age-matched males with typical development (TD; N = 35). We compared these percentages between the two groups (ASD and TD) and with scores on the social responsiveness scale (SRS). Further, we conducted discriminant analyses to determine if fixation times allocated to particular objects could be used to discriminate between individuals with and without ASD. RESULTS: Compared with the TD group, the ASD group showed significantly less fixation time at locations of salient social information (i.e., eyes in the movie of human faces without lip movement and people in the movie of people and geometry), while there were no significant groupwise differences in the responses to movies of human faces with lip movement or biological motion. In a within-group correlation analysis, a few of the fixation-time items correlated with SRS, although most of them did not. No items significantly correlated with SRS in both ASD and TD groups. The percentage fixation times to eyes and people, which exhibited large effect sizes for the group difference, could differentiate ASD and TD with a sensitivity of 81.0% and a specificity of 80.0%. CONCLUSIONS: These findings suggest that Gazefinder is potentially a valuable and easy-to-use tool for objectively measuring unique gaze patterns and discriminating between ASD and TD in male adolescents and adults. En ligne : http://dx.doi.org/10.1186/s13229-016-0083-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=328

Neural correlates of emotion processing during observed self-face recognition in individuals with autism spectrum disorders / Tomoyo MORITA in Research in Autism Spectrum Disorders, 26 (June 2016)  

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The impact of robotic intervention on joint attention in children with autism spectrum disorders / H. KUMAZAKI in Molecular Autism, 9 (2018)  

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