Dépouillements

What We Publish and What We Do Not / David G. AMARAL in Autism Research, 18-1 (January 2025)  

Public ISBD [article]  inAutism Research > 18-1 (January 2025) . - p.7-8 Titre : What We Publish and What We Do Not : Autism Research Type de document : Texte imprimé et/ou numérique Auteurs : David G. AMARAL, Auteur Article en page(s) : p.7-8 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.3307 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546 [article] What We Publish and What We Do Not : Autism Research [Texte imprimé et/ou numérique] / David G. AMARAL, Auteur . - p.7-8. Langues : Anglais (eng) in Autism Research > 18-1 (January 2025) . - p.7-8 Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.3307 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546

Autism Research: Thank You to Our 2024 Reviewers in Autism Research, 18-1 (January 2025)  

Public ISBD [article]  inAutism Research > 18-1 (January 2025) . - p.9-16 Titre : Autism Research: Thank You to Our 2024 Reviewers : Autism Research Type de document : Texte imprimé et/ou numérique Article en page(s) : p.9-16 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.3310 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546 [article] Autism Research: Thank You to Our 2024 Reviewers : Autism Research [Texte imprimé et/ou numérique] . - p.9-16. Langues : Anglais (eng) in Autism Research > 18-1 (January 2025) . - p.9-16 Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.3310 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546

Paradoxical relationship between cognitive abilities and camouflaging: Insights from ADHD and autism and its implications for neurodiversity research / Tina Taherkhani ; Amir Hossein MEMARI in Autism Research, 18-1 (January 2025)  

Public ISBD [article]  inAutism Research > 18-1 (January 2025) . - p.17-17 Titre : Paradoxical relationship between cognitive abilities and camouflaging: Insights from ADHD and autism and its implications for neurodiversity research : Autism Research Type de document : Texte imprimé et/ou numérique Auteurs : Tina Taherkhani, Auteur ; Amir Hossein MEMARI, Auteur Article en page(s) : p.17-17 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.3268 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546 [article] Paradoxical relationship between cognitive abilities and camouflaging: Insights from ADHD and autism and its implications for neurodiversity research : Autism Research [Texte imprimé et/ou numérique] / Tina Taherkhani, Auteur ; Amir Hossein MEMARI, Auteur . - p.17-17. Langues : Anglais (eng) in Autism Research > 18-1 (January 2025) . - p.17-17 Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.3268 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546

Exercise and autism spectrum disorder: Further considerations on cognitive and emotional impacts / Lizhen Huang ; Mingbang Wang ; Wenxian Huang ; Minyu Zhang ; Wei HE in Autism Research, 18-1 (January 2025)  

Public ISBD [article]  inAutism Research > 18-1 (January 2025) . - p.18-19 Titre : Exercise and autism spectrum disorder: Further considerations on cognitive and emotional impacts : Autism Research Type de document : Texte imprimé et/ou numérique Auteurs : Lizhen Huang, Auteur ; Mingbang Wang, Auteur ; Wenxian Huang, Auteur ; Minyu Zhang, Auteur ; Wei HE, Auteur Article en page(s) : p.18-19 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.3279 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546 [article] Exercise and autism spectrum disorder: Further considerations on cognitive and emotional impacts : Autism Research [Texte imprimé et/ou numérique] / Lizhen Huang, Auteur ; Mingbang Wang, Auteur ; Wenxian Huang, Auteur ; Minyu Zhang, Auteur ; Wei HE, Auteur . - p.18-19. Langues : Anglais (eng) in Autism Research > 18-1 (January 2025) . - p.18-19 Index. décimale : PER Périodiques En ligne : https://doi.org/10.1002/aur.3279 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546

Who, when, where, and why: A systematic review of "late diagnosis" in autism / Alison S. Russell ; Tyler C. MCFAYDEN ; Margaret McAllister ; Kimberly Liles ; Sophie Bittner ; John F. STRANG ; Clare HARROP in Autism Research, 18-1 (January 2025)  

Public ISBD [article]  inAutism Research > 18-1 (January 2025) . - p.22-36 Titre : Who, when, where, and why: A systematic review of "late diagnosis" in autism : Autism Research Type de document : Texte imprimé et/ou numérique Auteurs : Alison S. Russell, Auteur ; Tyler C. MCFAYDEN, Auteur ; Margaret McAllister, Auteur ; Kimberly Liles, Auteur ; Sophie Bittner, Auteur ; John F. STRANG, Auteur ; Clare HARROP, Auteur Article en page(s) : p.22-36 Langues : Anglais (eng) Mots-clés : age at diagnosis  ASD  autism  diagnosis  late diagnosis Index. décimale : PER Périodiques Résumé : Abstract An autism diagnosis can be a critical milestone toward effective and affirming support. Despite the sharp increase in the number of studies focused on late diagnosis over the last 15?years, there remains no consensus as to what constitutes a late diagnosis of autism, with cutoffs ranging from infancy to middle adulthood. This preregistered systematic review evaluated (a) the field's current quantification of late diagnosis in autism, (b) how the threshold for late diagnosis varies as a function of demographic and population factors, and (c) trends over time. Of the 11,697 records retrieved, N?=?420 articles met inclusion criteria and were extracted. Articles spanned 35?years (1989?2024) and included participants from every continent except Antarctica. Only 34.7% of included studies provided a clear threshold for ?late diagnosis? (n?=?146/420). Late diagnosis cutoffs averaged 11.53?years (range?=?2?55?years; median?=?6.5?years) with a bimodal distribution (3 and 18?years). The threshold for late diagnosis varied by participant location, F(5,140)?=?10.4, p? En ligne : https://doi.org/10.1002/aur.3278 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546 [article] Who, when, where, and why: A systematic review of "late diagnosis" in autism : Autism Research [Texte imprimé et/ou numérique] / Alison S. Russell, Auteur ; Tyler C. MCFAYDEN, Auteur ; Margaret McAllister, Auteur ; Kimberly Liles, Auteur ; Sophie Bittner, Auteur ; John F. STRANG, Auteur ; Clare HARROP, Auteur . - p.22-36. Langues : Anglais (eng) in Autism Research > 18-1 (January 2025) . - p.22-36 Mots-clés : age at diagnosis  ASD  autism  diagnosis  late diagnosis Index. décimale : PER Périodiques Résumé : Abstract An autism diagnosis can be a critical milestone toward effective and affirming support. Despite the sharp increase in the number of studies focused on late diagnosis over the last 15?years, there remains no consensus as to what constitutes a late diagnosis of autism, with cutoffs ranging from infancy to middle adulthood. This preregistered systematic review evaluated (a) the field's current quantification of late diagnosis in autism, (b) how the threshold for late diagnosis varies as a function of demographic and population factors, and (c) trends over time. Of the 11,697 records retrieved, N?=?420 articles met inclusion criteria and were extracted. Articles spanned 35?years (1989?2024) and included participants from every continent except Antarctica. Only 34.7% of included studies provided a clear threshold for ?late diagnosis? (n?=?146/420). Late diagnosis cutoffs averaged 11.53?years (range?=?2?55?years; median?=?6.5?years) with a bimodal distribution (3 and 18?years). The threshold for late diagnosis varied by participant location, F(5,140)?=?10.4, p? En ligne : https://doi.org/10.1002/aur.3278 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546

Is it still autism? The increasing broadening of the autism spectrum / Marco O. Bertelli ; Veronica Boniotti ; Katrina SCIOR in Autism Research, 18-1 (January 2025)  

Public ISBD [article]  inAutism Research > 18-1 (January 2025) . - p.37-43 Titre : Is it still autism? The increasing broadening of the autism spectrum : Autism Research Type de document : Texte imprimé et/ou numérique Auteurs : Marco O. Bertelli, Auteur ; Veronica Boniotti, Auteur ; Katrina SCIOR, Auteur Article en page(s) : p.37-43 Langues : Anglais (eng) Mots-clés : autism spectrum  autism traits  broad autism phenotype  diagnosis  outcome  subthreshold autism Index. décimale : PER Périodiques Résumé : Abstract Clinical significance of a broad autism phenotype (BAP) seems to be increasingly supported by growing reports of high prevalence of subthreshold autism spectrum disorder (sASD) or autistic traits (AT) in various demographic samples, particularly in individuals with psychiatric conditions. We question this increasing extension of the autism spectrum and its potential negative consequences for clinical services, research, cultural attitudes, and resource allocation, as well as alternative explanations of what is currently attributed to sASD and AT. In modern psychiatry the diagnostic threshold is paramount and associated with a significant impairment of functioning, implying that symptom specificity is more relevant than sensitivity. Within a syndrome, symptoms have to be present together, with the parts related to and interconnected with the whole. Single autism symptomatic dimensions have low syndromic specificity and can be observed in many different mental disorders. For instance, communication problems may present in communication disorders, social-cognitive difficulties can be found in schizophrenia, and rigid and/or repetitive behaviors can be found in obsessive compulsive disorder. One alternative interpretation of AT and/or sASD relates to personality traits. For example, within the Big 5 Model, low openness is associated with a dislike of change and a narrow range of interests, low extraversion with social withdrawal and coldness, and low agreeableness with disinterest in others and disregard for their feelings. These risks of overreliance on non-specific aspects of autism are particularly likely to occur with screening checklists, self-assessment, or assessment by a lay interviewer with only limited expertise in clinical assessment. En ligne : https://doi.org/10.1002/aur.3282 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546 [article] Is it still autism? The increasing broadening of the autism spectrum : Autism Research [Texte imprimé et/ou numérique] / Marco O. Bertelli, Auteur ; Veronica Boniotti, Auteur ; Katrina SCIOR, Auteur . - p.37-43. Langues : Anglais (eng) in Autism Research > 18-1 (January 2025) . - p.37-43 Mots-clés : autism spectrum  autism traits  broad autism phenotype  diagnosis  outcome  subthreshold autism Index. décimale : PER Périodiques Résumé : Abstract Clinical significance of a broad autism phenotype (BAP) seems to be increasingly supported by growing reports of high prevalence of subthreshold autism spectrum disorder (sASD) or autistic traits (AT) in various demographic samples, particularly in individuals with psychiatric conditions. We question this increasing extension of the autism spectrum and its potential negative consequences for clinical services, research, cultural attitudes, and resource allocation, as well as alternative explanations of what is currently attributed to sASD and AT. In modern psychiatry the diagnostic threshold is paramount and associated with a significant impairment of functioning, implying that symptom specificity is more relevant than sensitivity. Within a syndrome, symptoms have to be present together, with the parts related to and interconnected with the whole. Single autism symptomatic dimensions have low syndromic specificity and can be observed in many different mental disorders. For instance, communication problems may present in communication disorders, social-cognitive difficulties can be found in schizophrenia, and rigid and/or repetitive behaviors can be found in obsessive compulsive disorder. One alternative interpretation of AT and/or sASD relates to personality traits. For example, within the Big 5 Model, low openness is associated with a dislike of change and a narrow range of interests, low extraversion with social withdrawal and coldness, and low agreeableness with disinterest in others and disregard for their feelings. These risks of overreliance on non-specific aspects of autism are particularly likely to occur with screening checklists, self-assessment, or assessment by a lay interviewer with only limited expertise in clinical assessment. En ligne : https://doi.org/10.1002/aur.3282 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546

Exploring congenital sucrase-isomaltase deficiency in autism spectrum disorder patients with irritable bowel syndrome symptoms: A prospective gene sequencing study / Tanyel ZUBARIOGLU ; Dilara Ulgen ; Sedanur Akca-Yesil ; Selin Akbulut ; Huseyin Onay ; Gozde Uzunyayla-Inci ; Omer Faruk Beser ; Ali ?brahim Hatemi ; Çi?dem Aktu?lu-Zeybek ; Ertu?rul Kiykim in Autism Research, 18-1 (January 2025)  

Public ISBD [article]  inAutism Research > 18-1 (January 2025) . - p.44-55 Titre : Exploring congenital sucrase-isomaltase deficiency in autism spectrum disorder patients with irritable bowel syndrome symptoms: A prospective gene sequencing study : Autism Research Type de document : Texte imprimé et/ou numérique Auteurs : Tanyel ZUBARIOGLU, Auteur ; Dilara Ulgen, Auteur ; Sedanur Akca-Yesil, Auteur ; Selin Akbulut, Auteur ; Huseyin Onay, Auteur ; Gozde Uzunyayla-Inci, Auteur ; Omer Faruk Beser, Auteur ; Ali ?brahim Hatemi, Auteur ; Çi?dem Aktu?lu-Zeybek, Auteur ; Ertu?rul Kiykim, Auteur Article en page(s) : p.44-55 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  CSID  heterozygous  prospective screening  SI gene Index. décimale : PER Périodiques Résumé : Abstract Congenital sucrase-isomaltase deficiency (CSID) is an inherited metabolic disorder causing chronic gastrointestinal symptoms and malnutrition when untreated. Most CSID patients are likely to remain under- or misdiagnosed. This study aimed to investigate prevalence of CSID among patients with autism spectrum disorder (ASD) presenting with irritable bowel syndrome (IBS) symptoms via prospective SI gene sequencing. A prospective cross-sectional study was conducted on 98 ASD patients exhibiting gastrointestinal symptoms consistent with IBS. Participants were assessed according to Rome IV criteria and underwent SI gene sequencing. Demographic, clinical, and dietary data were collected and analyzed. Sucrose content in various fruits and vegetables was evaluated using three-day food record, and gastrointestinal symptoms were rated on Likert scale. Seven patients (7%) were diagnosed with CSID based on SI gene analysis, revealing six different variants, including four novel mutations. One patient was homozygous for one variant, and six patients were heterozygous. Clinical presentations predominantly included diarrhea, abdominal pain, and bloating, with two patients showing growth retardation. One patient was diagnosed in adulthood. Food allergy and lactose intolerance were the misdiagnoses prior to CSID diagnosis in two patients. Real prevalence of CSID is likely underestimated. Clinical heterogeneity and non-specific symptoms contribute to diagnostic challenges. Gastrointestinal symptoms consistent with IBS in ASD patients should include CSID in differential diagnosis. Early genetic screening for SI variants in ASD patients with IBS symptoms can facilitate timely diagnosis and management, improving outcomes. Heterozygous variants of the SI gene should also be considered, as heterozygous patients can exhibit typical CSID symptoms. En ligne : https://doi.org/10.1002/aur.3293 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546 [article] Exploring congenital sucrase-isomaltase deficiency in autism spectrum disorder patients with irritable bowel syndrome symptoms: A prospective gene sequencing study : Autism Research [Texte imprimé et/ou numérique] / Tanyel ZUBARIOGLU, Auteur ; Dilara Ulgen, Auteur ; Sedanur Akca-Yesil, Auteur ; Selin Akbulut, Auteur ; Huseyin Onay, Auteur ; Gozde Uzunyayla-Inci, Auteur ; Omer Faruk Beser, Auteur ; Ali ?brahim Hatemi, Auteur ; Çi?dem Aktu?lu-Zeybek, Auteur ; Ertu?rul Kiykim, Auteur . - p.44-55. Langues : Anglais (eng) in Autism Research > 18-1 (January 2025) . - p.44-55 Mots-clés : autism spectrum disorder  CSID  heterozygous  prospective screening  SI gene Index. décimale : PER Périodiques Résumé : Abstract Congenital sucrase-isomaltase deficiency (CSID) is an inherited metabolic disorder causing chronic gastrointestinal symptoms and malnutrition when untreated. Most CSID patients are likely to remain under- or misdiagnosed. This study aimed to investigate prevalence of CSID among patients with autism spectrum disorder (ASD) presenting with irritable bowel syndrome (IBS) symptoms via prospective SI gene sequencing. A prospective cross-sectional study was conducted on 98 ASD patients exhibiting gastrointestinal symptoms consistent with IBS. Participants were assessed according to Rome IV criteria and underwent SI gene sequencing. Demographic, clinical, and dietary data were collected and analyzed. Sucrose content in various fruits and vegetables was evaluated using three-day food record, and gastrointestinal symptoms were rated on Likert scale. Seven patients (7%) were diagnosed with CSID based on SI gene analysis, revealing six different variants, including four novel mutations. One patient was homozygous for one variant, and six patients were heterozygous. Clinical presentations predominantly included diarrhea, abdominal pain, and bloating, with two patients showing growth retardation. One patient was diagnosed in adulthood. Food allergy and lactose intolerance were the misdiagnoses prior to CSID diagnosis in two patients. Real prevalence of CSID is likely underestimated. Clinical heterogeneity and non-specific symptoms contribute to diagnostic challenges. Gastrointestinal symptoms consistent with IBS in ASD patients should include CSID in differential diagnosis. Early genetic screening for SI variants in ASD patients with IBS symptoms can facilitate timely diagnosis and management, improving outcomes. Heterozygous variants of the SI gene should also be considered, as heterozygous patients can exhibit typical CSID symptoms. En ligne : https://doi.org/10.1002/aur.3293 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546

Increased alpha power in autistic adults: Relation to sensory behaviors and cortical volume / Scott O. MURRAY ; Daniela L. Seczon ; Mark Pettet ; Hannah M. REA ; Kristin M. WOODARD ; Tamar KOLODNY ; Sara Jane WEBB in Autism Research, 18-1 (January 2025)  

Public ISBD [article]  inAutism Research > 18-1 (January 2025) . - p.56-69 Titre : Increased alpha power in autistic adults: Relation to sensory behaviors and cortical volume : Autism Research Type de document : Texte imprimé et/ou numérique Auteurs : Scott O. MURRAY, Auteur ; Daniela L. Seczon, Auteur ; Mark Pettet, Auteur ; Hannah M. REA, Auteur ; Kristin M. WOODARD, Auteur ; Tamar KOLODNY, Auteur ; Sara Jane WEBB, Auteur Article en page(s) : p.56-69 Langues : Anglais (eng) Mots-clés : alpha  autism spectrum disorder  EEG  sensory processing  vision Index. décimale : PER Périodiques Résumé : Abstract Alpha-band (~10?Hz) neural oscillations, crucial for gating sensory information, may offer insights into the atypical sensory experiences characteristic of autism spectrum disorder (ASD). We investigated alpha-band EEG activity in autistic adults (n?=?29) compared with a nonautistic group (n?=?23) under various stimulus-driven and resting-state conditions. The autistic group showed consistently higher alpha amplitude across all time points. In addition, there was proportionally more suppression of alpha at stimulus onset in the autistic group, and alpha amplitude in this stimulus-onset period correlated with sensory behaviors. Recent research suggests a link between subcortical structures' volume and cortical alpha magnitude. Prompted by this, we explored the association between alpha power and the volume of subcortical structures and total cortical volume in ASD. Our findings indicate a significant correlation with total cortical volume and a group by hippocampal volume interaction, pointing to the potential role of anatomical structural characteristics as potential modulators of cortical alpha oscillations in ASD. Overall, the results highlight altered alpha in autistic individuals as potentially contributing to the heightened sensory symptoms in autistic compared with nonautistic adults. En ligne : https://doi.org/10.1002/aur.3266 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546 [article] Increased alpha power in autistic adults: Relation to sensory behaviors and cortical volume : Autism Research [Texte imprimé et/ou numérique] / Scott O. MURRAY, Auteur ; Daniela L. Seczon, Auteur ; Mark Pettet, Auteur ; Hannah M. REA, Auteur ; Kristin M. WOODARD, Auteur ; Tamar KOLODNY, Auteur ; Sara Jane WEBB, Auteur . - p.56-69. Langues : Anglais (eng) in Autism Research > 18-1 (January 2025) . - p.56-69 Mots-clés : alpha  autism spectrum disorder  EEG  sensory processing  vision Index. décimale : PER Périodiques Résumé : Abstract Alpha-band (~10?Hz) neural oscillations, crucial for gating sensory information, may offer insights into the atypical sensory experiences characteristic of autism spectrum disorder (ASD). We investigated alpha-band EEG activity in autistic adults (n?=?29) compared with a nonautistic group (n?=?23) under various stimulus-driven and resting-state conditions. The autistic group showed consistently higher alpha amplitude across all time points. In addition, there was proportionally more suppression of alpha at stimulus onset in the autistic group, and alpha amplitude in this stimulus-onset period correlated with sensory behaviors. Recent research suggests a link between subcortical structures' volume and cortical alpha magnitude. Prompted by this, we explored the association between alpha power and the volume of subcortical structures and total cortical volume in ASD. Our findings indicate a significant correlation with total cortical volume and a group by hippocampal volume interaction, pointing to the potential role of anatomical structural characteristics as potential modulators of cortical alpha oscillations in ASD. Overall, the results highlight altered alpha in autistic individuals as potentially contributing to the heightened sensory symptoms in autistic compared with nonautistic adults. En ligne : https://doi.org/10.1002/aur.3266 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546

Subregion-specific thalamocortical functional connectivity, executive function, and social behavior in children with autism spectrum disorders / Jasmine Si Min Chuah ; Aisleen M. A. Manahan ; Shi Yu Chan ; Zhen Ming Ngoh ; Pei Huang ; Ai Peng TAN in Autism Research, 18-1 (January 2025)  

Public ISBD [article]  inAutism Research > 18-1 (January 2025) . - p.70-82 Titre : Subregion-specific thalamocortical functional connectivity, executive function, and social behavior in children with autism spectrum disorders : Autism Research Type de document : Texte imprimé et/ou numérique Auteurs : Jasmine Si Min Chuah, Auteur ; Aisleen M. A. Manahan, Auteur ; Shi Yu Chan, Auteur ; Zhen Ming Ngoh, Auteur ; Pei Huang, Auteur ; Ai Peng TAN, Auteur Article en page(s) : p.70-82 Langues : Anglais (eng) Mots-clés : autism spectrum disorders (ASDs)  children  executive function  resting-state functional connectivity (RSFC)  social behavior  thalamocortical connectivity Index. décimale : PER Périodiques Résumé : Abstract The thalamus has extensive cortical connections and is an integrative hub for cognitive functions governing social behavior. This study examined (1) associations between thalamocortical resting-state functional connectivity (RSFC) and social behavior in children and (2) how various executive function (EF) subdomains mediate the association between thalamocortical RSFC and social behavior. Children from the autism brain imaging data exchange (ABIDE) initiative with neuroimaging, behavioral, and demographic data were included in our study (age En ligne : https://doi.org/10.1002/aur.3280 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546 [article] Subregion-specific thalamocortical functional connectivity, executive function, and social behavior in children with autism spectrum disorders : Autism Research [Texte imprimé et/ou numérique] / Jasmine Si Min Chuah, Auteur ; Aisleen M. A. Manahan, Auteur ; Shi Yu Chan, Auteur ; Zhen Ming Ngoh, Auteur ; Pei Huang, Auteur ; Ai Peng TAN, Auteur . - p.70-82. Langues : Anglais (eng) in Autism Research > 18-1 (January 2025) . - p.70-82 Mots-clés : autism spectrum disorders (ASDs)  children  executive function  resting-state functional connectivity (RSFC)  social behavior  thalamocortical connectivity Index. décimale : PER Périodiques Résumé : Abstract The thalamus has extensive cortical connections and is an integrative hub for cognitive functions governing social behavior. This study examined (1) associations between thalamocortical resting-state functional connectivity (RSFC) and social behavior in children and (2) how various executive function (EF) subdomains mediate the association between thalamocortical RSFC and social behavior. Children from the autism brain imaging data exchange (ABIDE) initiative with neuroimaging, behavioral, and demographic data were included in our study (age En ligne : https://doi.org/10.1002/aur.3280 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546

Abnormalities in cerebellar subregions' volume and cerebellocerebral structural covariance in autism spectrum disorder / Yu WANG ; Aihua Cao ; Jing WANG ; He Bai ; Tianci Liu ; Chenxi Sun ; Zhuoran Li ; Yuchun Tang ; Feifei Xu ; Shuwei Liu in Autism Research, 18-1 (January 2025)  

Public ISBD [article]  inAutism Research > 18-1 (January 2025) . - p.83-97 Titre : Abnormalities in cerebellar subregions' volume and cerebellocerebral structural covariance in autism spectrum disorder : Autism Research Type de document : Texte imprimé et/ou numérique Auteurs : Yu WANG, Auteur ; Aihua Cao, Auteur ; Jing WANG, Auteur ; He Bai, Auteur ; Tianci Liu, Auteur ; Chenxi Sun, Auteur ; Zhuoran Li, Auteur ; Yuchun Tang, Auteur ; Feifei Xu, Auteur ; Shuwei Liu, Auteur Article en page(s) : p.83-97 Langues : Anglais (eng) Mots-clés : atypical patterns  autism  cerebellar subregions' volume  cerebellocerebral structural covariance  pars opercularis Index. décimale : PER Périodiques Résumé : Abstract The cerebellum plays a crucial role in functions, including sensory-motor coordination, cognition, and emotional processing. Compared to the neocortex, the human cerebellum exhibits a protracted developmental trajectory. This delayed developmental timeline may lead to increased sensitivity of the cerebellum to external influences, potentially extending the vulnerability period for neurological disorders. Abnormal cerebellar development in individuals with autism has been confirmed, and these atypical cerebellar changes may affect the development of the neocortex. However, due to the heterogeneity of autism spectrum disorder (ASD), the regional changes in the cerebellum and cerebellocerebral structural relationship remain unknown. To address these issues, we utilized imaging methods optimized for the cerebellum and cerebrum on 817 individuals aged 5?18?years in the ABIDE II dataset. After FDR correction, significant differences between groups were found in the right crus II/VIIB and vermis VI-VII. Structural covariance analysis revealed enhanced structural covariance in individuals with autism between the cerebellum and parahippocampal gyrus, pars opercularis, and transverse temporal gyrus in the right hemisphere after FDR correction. Furthermore, the structural covariance between the cerebellum and some regions of the cerebrum varied across sexes. A significant increase in structural covariance between the cerebellum and specific subcortical structures was also observed in individuals with ASD. Our study found atypical patterns in the structural covariance between the cerebellum and cerebrum in individuals with autism, which suggested that the underlying pathological processes of ASD might concurrently affect these brain regions. This study provided insight into the potential of cerebellocerebral pathways as therapeutic targets for ASD. En ligne : https://doi.org/10.1002/aur.3287 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546 [article] Abnormalities in cerebellar subregions' volume and cerebellocerebral structural covariance in autism spectrum disorder : Autism Research [Texte imprimé et/ou numérique] / Yu WANG, Auteur ; Aihua Cao, Auteur ; Jing WANG, Auteur ; He Bai, Auteur ; Tianci Liu, Auteur ; Chenxi Sun, Auteur ; Zhuoran Li, Auteur ; Yuchun Tang, Auteur ; Feifei Xu, Auteur ; Shuwei Liu, Auteur . - p.83-97. Langues : Anglais (eng) in Autism Research > 18-1 (January 2025) . - p.83-97 Mots-clés : atypical patterns  autism  cerebellar subregions' volume  cerebellocerebral structural covariance  pars opercularis Index. décimale : PER Périodiques Résumé : Abstract The cerebellum plays a crucial role in functions, including sensory-motor coordination, cognition, and emotional processing. Compared to the neocortex, the human cerebellum exhibits a protracted developmental trajectory. This delayed developmental timeline may lead to increased sensitivity of the cerebellum to external influences, potentially extending the vulnerability period for neurological disorders. Abnormal cerebellar development in individuals with autism has been confirmed, and these atypical cerebellar changes may affect the development of the neocortex. However, due to the heterogeneity of autism spectrum disorder (ASD), the regional changes in the cerebellum and cerebellocerebral structural relationship remain unknown. To address these issues, we utilized imaging methods optimized for the cerebellum and cerebrum on 817 individuals aged 5?18?years in the ABIDE II dataset. After FDR correction, significant differences between groups were found in the right crus II/VIIB and vermis VI-VII. Structural covariance analysis revealed enhanced structural covariance in individuals with autism between the cerebellum and parahippocampal gyrus, pars opercularis, and transverse temporal gyrus in the right hemisphere after FDR correction. Furthermore, the structural covariance between the cerebellum and some regions of the cerebrum varied across sexes. A significant increase in structural covariance between the cerebellum and specific subcortical structures was also observed in individuals with ASD. Our study found atypical patterns in the structural covariance between the cerebellum and cerebrum in individuals with autism, which suggested that the underlying pathological processes of ASD might concurrently affect these brain regions. This study provided insight into the potential of cerebellocerebral pathways as therapeutic targets for ASD. En ligne : https://doi.org/10.1002/aur.3287 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546

Elevated parkinsonism symptoms in autism during middle and older adulthood are linked with psychosocial, physical health, and mental health outcomes / Gregory L. WALLACE ; Alex Job SAID ; Goldie A. MCQUAID in Autism Research, 18-1 (January 2025)  

Public ISBD [article]  inAutism Research > 18-1 (January 2025) . - p.98-109 Titre : Elevated parkinsonism symptoms in autism during middle and older adulthood are linked with psychosocial, physical health, and mental health outcomes : Autism Research Type de document : Texte imprimé et/ou numérique Auteurs : Gregory L. WALLACE, Auteur ; Alex Job SAID, Auteur ; Goldie A. MCQUAID, Auteur Article en page(s) : p.98-109 Langues : Anglais (eng) Mots-clés : autism  bradykinesia  motor  parkinsonism  Parkinson's disease  tremor Index. décimale : PER Périodiques Résumé : Abstract Evidence is growing for a link between parkinsonism, or the motor symptoms associated with Parkinson's Disease and autism. However, research to date has yet to examine whether the presence of these motoric symptoms impacts critical adult outcomes in autism. Therefore, the current study utilized a screening measure to bifurcate a relatively large (n?=?379) sample of middle and older age autistic adults (40?83?years) into parkinsonism screen positive (n?=?119) versus parkinsonism screen negative (n?=?260) groups in order to compare them on broad metrics of daily living skills and subjective quality of life as well as non-motoric features linked to parkinsonism, namely memory problems, sleep quality, and depression symptoms. Overall, co-occurring parkinsonism was linked with lower subjective quality of life, more memory problems, lower sleep quality, and greater depression symptoms in autistic adults. Taken together, these findings implicate an important co-occurring motoric phenotype in middle and older adulthood for autistic people that could have significant real-world impacts yet has been largely neglected in the extant literature to date. En ligne : https://doi.org/10.1002/aur.3274 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546 [article] Elevated parkinsonism symptoms in autism during middle and older adulthood are linked with psychosocial, physical health, and mental health outcomes : Autism Research [Texte imprimé et/ou numérique] / Gregory L. WALLACE, Auteur ; Alex Job SAID, Auteur ; Goldie A. MCQUAID, Auteur . - p.98-109. Langues : Anglais (eng) in Autism Research > 18-1 (January 2025) . - p.98-109 Mots-clés : autism  bradykinesia  motor  parkinsonism  Parkinson's disease  tremor Index. décimale : PER Périodiques Résumé : Abstract Evidence is growing for a link between parkinsonism, or the motor symptoms associated with Parkinson's Disease and autism. However, research to date has yet to examine whether the presence of these motoric symptoms impacts critical adult outcomes in autism. Therefore, the current study utilized a screening measure to bifurcate a relatively large (n?=?379) sample of middle and older age autistic adults (40?83?years) into parkinsonism screen positive (n?=?119) versus parkinsonism screen negative (n?=?260) groups in order to compare them on broad metrics of daily living skills and subjective quality of life as well as non-motoric features linked to parkinsonism, namely memory problems, sleep quality, and depression symptoms. Overall, co-occurring parkinsonism was linked with lower subjective quality of life, more memory problems, lower sleep quality, and greater depression symptoms in autistic adults. Taken together, these findings implicate an important co-occurring motoric phenotype in middle and older adulthood for autistic people that could have significant real-world impacts yet has been largely neglected in the extant literature to date. En ligne : https://doi.org/10.1002/aur.3274 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546

Offending and clinical characteristics of adults with autism spectrum disorder: Experience at forensic psychiatry center in Türkiye between 2012 and 2022 / Muhammed Emin Boylu ; Aynur Görmez ; ?enol Turan ; Ümit Haluk Ye?ilkaya ; Fatma Betül Boylu ; Alaattin Duran in Autism Research, 18-1 (January 2025)  

Public ISBD [article]  inAutism Research > 18-1 (January 2025) . - p.110-121 Titre : Offending and clinical characteristics of adults with autism spectrum disorder: Experience at forensic psychiatry center in Türkiye between 2012 and 2022 : Autism Research Type de document : Texte imprimé et/ou numérique Auteurs : Muhammed Emin Boylu, Auteur ; Aynur Görmez, Auteur ; ?enol Turan, Auteur ; Ümit Haluk Ye?ilkaya, Auteur ; Fatma Betül Boylu, Auteur ; Alaattin Duran, Auteur Article en page(s) : p.110-121 Langues : Anglais (eng) Mots-clés : adults  autism  criminal responsibility  forensic psychiatry  offense  Turkey  violence Index. décimale : PER Périodiques Résumé : Abstract The forensic and clinical need for better understanding of criminal offending in adults with ASD is increasingly recognized. To date, few studies have examined the differences and similarities between criminal offenders with and without ASD with respect to demographics, offending profiles, and clinical characteristics. This study, conducted in Turkey, is the first to conduct such as comparison using a national database of forensic files. Computerized search of the forensic records of 11,853 adults assessed between January 1, 2012, and January 1, 2022, for criminal responsibility by the Turkish Council of Forensic Medicine found 74 adults diagnosed with ASD; they ranged in age from 18 to 40. [Correction added after first online publication on 04 December 2024. The value 11,583 has been revised to 11,853.] The demographic, clinical, and offending characteristics of these adults were compared to 100 adults without ASD selected from the remaining 11,779 records based on age (18?40?years) and year of assessment (10 from each year). The ASD group was younger, more likely to be unemployed and not living on their own. The ASD group was more likely to have co-morbid intellectual disability, ADHD, and OCD, while the non-ASD group was more likely to have co-morbid personality disorders, The ASD group was more likely to commit unplanned simple (non-penetrative) sexual and violent offenses against strangers; the non-ASD group was more likely to commit planned, qualified (penetrative) crimes against known persons. Impulsivity and manipulability were more often contributory in persons with ASD; revenge was more often contributory in persons without ASD. Adults with ASD were more likely to commit crimes on social media. In conclusion, this study found that adult offenders with and without ASD differed in demographics, psychiatric co-morbidities, and types of offending behaviors. These differences may have implications for the prevention of criminal offending in persons with ASD and addressing their needs once they are in the criminal justice system. En ligne : https://doi.org/10.1002/aur.3275 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546 [article] Offending and clinical characteristics of adults with autism spectrum disorder: Experience at forensic psychiatry center in Türkiye between 2012 and 2022 : Autism Research [Texte imprimé et/ou numérique] / Muhammed Emin Boylu, Auteur ; Aynur Görmez, Auteur ; ?enol Turan, Auteur ; Ümit Haluk Ye?ilkaya, Auteur ; Fatma Betül Boylu, Auteur ; Alaattin Duran, Auteur . - p.110-121. Langues : Anglais (eng) in Autism Research > 18-1 (January 2025) . - p.110-121 Mots-clés : adults  autism  criminal responsibility  forensic psychiatry  offense  Turkey  violence Index. décimale : PER Périodiques Résumé : Abstract The forensic and clinical need for better understanding of criminal offending in adults with ASD is increasingly recognized. To date, few studies have examined the differences and similarities between criminal offenders with and without ASD with respect to demographics, offending profiles, and clinical characteristics. This study, conducted in Turkey, is the first to conduct such as comparison using a national database of forensic files. Computerized search of the forensic records of 11,853 adults assessed between January 1, 2012, and January 1, 2022, for criminal responsibility by the Turkish Council of Forensic Medicine found 74 adults diagnosed with ASD; they ranged in age from 18 to 40. [Correction added after first online publication on 04 December 2024. The value 11,583 has been revised to 11,853.] The demographic, clinical, and offending characteristics of these adults were compared to 100 adults without ASD selected from the remaining 11,779 records based on age (18?40?years) and year of assessment (10 from each year). The ASD group was younger, more likely to be unemployed and not living on their own. The ASD group was more likely to have co-morbid intellectual disability, ADHD, and OCD, while the non-ASD group was more likely to have co-morbid personality disorders, The ASD group was more likely to commit unplanned simple (non-penetrative) sexual and violent offenses against strangers; the non-ASD group was more likely to commit planned, qualified (penetrative) crimes against known persons. Impulsivity and manipulability were more often contributory in persons with ASD; revenge was more often contributory in persons without ASD. Adults with ASD were more likely to commit crimes on social media. In conclusion, this study found that adult offenders with and without ASD differed in demographics, psychiatric co-morbidities, and types of offending behaviors. These differences may have implications for the prevention of criminal offending in persons with ASD and addressing their needs once they are in the criminal justice system. En ligne : https://doi.org/10.1002/aur.3275 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546

Adapting measures of motor imitation for use by caregivers in virtual contexts: Reliability, validity, and sensitivity to change / Brooke INGERSOLL ; Mya HOWARD ; Devon OOSTING ; Alice S. CARTER ; Wendy L. STONE ; Natalie Berger ; Allison L. WAINER ; Emily R. Britsch ; Rise Research Network in Autism Research, 18-1 (January 2025)  

Public ISBD [article]  inAutism Research > 18-1 (January 2025) . - p.122-132 Titre : Adapting measures of motor imitation for use by caregivers in virtual contexts: Reliability, validity, and sensitivity to change : Autism Research Type de document : Texte imprimé et/ou numérique Auteurs : Brooke INGERSOLL, Auteur ; Mya HOWARD, Auteur ; Devon OOSTING, Auteur ; Alice S. CARTER, Auteur ; Wendy L. STONE, Auteur ; Natalie Berger, Auteur ; Allison L. WAINER, Auteur ; Emily R. Britsch, Auteur ; Rise Research Network, Auteur Article en page(s) : p.122-132 Langues : Anglais (eng) Mots-clés : assessment  autism  caregiver-implemented  imitation  virtual Index. décimale : PER Périodiques Résumé : Abstract Early imitation challenges for children with autism are thought to contribute to broader delays in their social communication development. As such, imitation is an important intervention target for young children with and showing early signs of autism, and efforts are underway to disseminate evidence-based imitation interventions into community settings. To our knowledge, there are currently no established imitation assessments that have been validated for use in virtual contexts. This study was designed to examine the reliability and validity of two caregiver-implemented imitation measures delivered with support from a remote virtual assessor. Study participants (177 caregiver-child dyads) were enrolled in a large, multisite study that is examining the effectiveness of a caregiver-implemented intervention delivered through the Part C early intervention (EI) system across four states. Results indicate that the assessments can be administered remotely with strong fidelity, internal reliability, predictive validity, discriminant validity, convergent validity, and sensitivity to change. Stability over time was adequate. These findings suggest that imitation skills can be measured effectively using a remote caregiver-implemented assessment, which provides greater opportunity for virtual clinical trials targeting social communication in young children. Clinical Trial Registration The trial protocol was registered at ClinicalTrials.gov (NCT05114538). En ligne : https://doi.org/10.1002/aur.3267 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546 [article] Adapting measures of motor imitation for use by caregivers in virtual contexts: Reliability, validity, and sensitivity to change : Autism Research [Texte imprimé et/ou numérique] / Brooke INGERSOLL, Auteur ; Mya HOWARD, Auteur ; Devon OOSTING, Auteur ; Alice S. CARTER, Auteur ; Wendy L. STONE, Auteur ; Natalie Berger, Auteur ; Allison L. WAINER, Auteur ; Emily R. Britsch, Auteur ; Rise Research Network, Auteur . - p.122-132. Langues : Anglais (eng) in Autism Research > 18-1 (January 2025) . - p.122-132 Mots-clés : assessment  autism  caregiver-implemented  imitation  virtual Index. décimale : PER Périodiques Résumé : Abstract Early imitation challenges for children with autism are thought to contribute to broader delays in their social communication development. As such, imitation is an important intervention target for young children with and showing early signs of autism, and efforts are underway to disseminate evidence-based imitation interventions into community settings. To our knowledge, there are currently no established imitation assessments that have been validated for use in virtual contexts. This study was designed to examine the reliability and validity of two caregiver-implemented imitation measures delivered with support from a remote virtual assessor. Study participants (177 caregiver-child dyads) were enrolled in a large, multisite study that is examining the effectiveness of a caregiver-implemented intervention delivered through the Part C early intervention (EI) system across four states. Results indicate that the assessments can be administered remotely with strong fidelity, internal reliability, predictive validity, discriminant validity, convergent validity, and sensitivity to change. Stability over time was adequate. These findings suggest that imitation skills can be measured effectively using a remote caregiver-implemented assessment, which provides greater opportunity for virtual clinical trials targeting social communication in young children. Clinical Trial Registration The trial protocol was registered at ClinicalTrials.gov (NCT05114538). En ligne : https://doi.org/10.1002/aur.3267 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546

Exploring the Heterogeneity of Self-Injurious Behaviors in Autistic Youth: Patterns, Predictors, and Implications for Intervention / Emily F. FERGUSON ; Emily SPACKMAN ; Ru Ying CAI ; Antonio Y. HARDAN ; Mirko ULJAREVI? in Autism Research, 18-1 (January 2025)  

Public ISBD [article]  inAutism Research > 18-1 (January 2025) . - p.133-151 Titre : Exploring the Heterogeneity of Self-Injurious Behaviors in Autistic Youth: Patterns, Predictors, and Implications for Intervention : Autism Research Type de document : Texte imprimé et/ou numérique Auteurs : Emily F. FERGUSON, Auteur ; Emily SPACKMAN, Auteur ; Ru Ying CAI, Auteur ; Antonio Y. HARDAN, Auteur ; Mirko ULJAREVI?, Auteur Article en page(s) : p.133-151 Langues : Anglais (eng) Mots-clés : adolescent  arousal  autism spectrum disorder  challenging behaviors  dysregulation  emotions  intellectual disability  restricted and repetitive behaviors  self harm  self injurious behaviors  self injury  stereotypic movement disorder Index. décimale : PER Périodiques Résumé : Abstract Self-injurious behaviors (SIB) encompass a heterogeneous set of self-inflicted aggressive behaviors that are highly prevalent in autistic youth. Existing research on SIB in autism spectrum disorder (ASD) has been limited by significant methodological and conceptual inconsistencies. Thus, the current study leveraged item-level data capturing the severity of unique SIB topographies to further understanding of factors associated with distinct SIB in a sample of 582 autistic youth (Mage?=?12.12, SDage?=?3.68; range: 3?19?years; 13% females). Results suggest variation in severity endorsements for specific SIB topographies amongst autistic youth, such that 30%?50% of caregivers endorsed slight to very serious concern regarding the SIB topographies of bites nails/skin/fingers, scratches self, hits head/face/neck, bangs head against things, and picks skin. Generalized additive models demonstrated distinct patterns of associations between each SIB topography and dysregulation, sensory hypersensitivity, age, sex, IQ, and language level. Findings underscore the importance of exploring SIB as a multifaceted construct to capture unique correlates of distinct SIB that vary in severity and functional impact, which is critical for the development of effective interventions. This study represents an important step towards more individualized characterization of SIB and support for diverse presentations of these behaviors in autistic youth. En ligne : https://doi.org/10.1002/aur.3269 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546 [article] Exploring the Heterogeneity of Self-Injurious Behaviors in Autistic Youth: Patterns, Predictors, and Implications for Intervention : Autism Research [Texte imprimé et/ou numérique] / Emily F. FERGUSON, Auteur ; Emily SPACKMAN, Auteur ; Ru Ying CAI, Auteur ; Antonio Y. HARDAN, Auteur ; Mirko ULJAREVI?, Auteur . - p.133-151. Langues : Anglais (eng) in Autism Research > 18-1 (January 2025) . - p.133-151 Mots-clés : adolescent  arousal  autism spectrum disorder  challenging behaviors  dysregulation  emotions  intellectual disability  restricted and repetitive behaviors  self harm  self injurious behaviors  self injury  stereotypic movement disorder Index. décimale : PER Périodiques Résumé : Abstract Self-injurious behaviors (SIB) encompass a heterogeneous set of self-inflicted aggressive behaviors that are highly prevalent in autistic youth. Existing research on SIB in autism spectrum disorder (ASD) has been limited by significant methodological and conceptual inconsistencies. Thus, the current study leveraged item-level data capturing the severity of unique SIB topographies to further understanding of factors associated with distinct SIB in a sample of 582 autistic youth (Mage?=?12.12, SDage?=?3.68; range: 3?19?years; 13% females). Results suggest variation in severity endorsements for specific SIB topographies amongst autistic youth, such that 30%?50% of caregivers endorsed slight to very serious concern regarding the SIB topographies of bites nails/skin/fingers, scratches self, hits head/face/neck, bangs head against things, and picks skin. Generalized additive models demonstrated distinct patterns of associations between each SIB topography and dysregulation, sensory hypersensitivity, age, sex, IQ, and language level. Findings underscore the importance of exploring SIB as a multifaceted construct to capture unique correlates of distinct SIB that vary in severity and functional impact, which is critical for the development of effective interventions. This study represents an important step towards more individualized characterization of SIB and support for diverse presentations of these behaviors in autistic youth. En ligne : https://doi.org/10.1002/aur.3269 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546

Narrative abilities of autistic and non-autistic adolescents: The role of mentalising and executive function / Anna HARVEY ; Helen SPICER-CAIN ; Nicola BOTTING ; Lucy HENRY in Autism Research, 18-1 (January 2025)  

Public ISBD [article]  inAutism Research > 18-1 (January 2025) . - p.152-165 Titre : Narrative abilities of autistic and non-autistic adolescents: The role of mentalising and executive function : Autism Research Type de document : Texte imprimé et/ou numérique Auteurs : Anna HARVEY, Auteur ; Helen SPICER-CAIN, Auteur ; Nicola BOTTING, Auteur ; Lucy HENRY, Auteur Article en page(s) : p.152-165 Langues : Anglais (eng) Mots-clés : adolescents  executive functioning  language  social cognition & Theory of Mind Index. décimale : PER Périodiques Résumé : Abstract Spoken narrative skills are important for adolescents in their everyday lives. Previous research suggests that producing well-structured and coherent narratives may be challenging for autistic young people. Mentalising, also known as ?advanced Theory of Mind? (ToM) and ?Executive Function? (EF) are two cognitive abilities frequently explored in relation to autism, both of which may be implicated in narrative ability. The present study investigated these relationships in a group of autistic adolescents (N?=?44) aged 11?15?years and a comparable non-autistic group (N?=?54) that did not significantly differ on age, sex, nonverbal cognitive ability, or receptive/expressive language skills. Participants were assessed on a video-based spoken narrative task, scored for both overall structure (?story grammar?) and narrative coherence. A battery of tasks measuring mentalising and EF (working memory, inhibition, shifting, generativity) was also administered. Relationships between scores on cognitive measures and narrative performance were investigated using hierarchical linear regression analyses. Mentalising scores were found to significantly predict narrative performance across all outcome measures and were a stronger predictor than diagnostic group. Diagnostic group predicted narrative structure (?story grammar?) scores but not coherence scores. EF scores were not predictive of narrative ability in this sample. Mentalising skills appear to play an important role for both autistic and non-autistic adolescents in the generation of narrative structure and coherence within spoken accounts. En ligne : https://doi.org/10.1002/aur.3272 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546 [article] Narrative abilities of autistic and non-autistic adolescents: The role of mentalising and executive function : Autism Research [Texte imprimé et/ou numérique] / Anna HARVEY, Auteur ; Helen SPICER-CAIN, Auteur ; Nicola BOTTING, Auteur ; Lucy HENRY, Auteur . - p.152-165. Langues : Anglais (eng) in Autism Research > 18-1 (January 2025) . - p.152-165 Mots-clés : adolescents  executive functioning  language  social cognition & Theory of Mind Index. décimale : PER Périodiques Résumé : Abstract Spoken narrative skills are important for adolescents in their everyday lives. Previous research suggests that producing well-structured and coherent narratives may be challenging for autistic young people. Mentalising, also known as ?advanced Theory of Mind? (ToM) and ?Executive Function? (EF) are two cognitive abilities frequently explored in relation to autism, both of which may be implicated in narrative ability. The present study investigated these relationships in a group of autistic adolescents (N?=?44) aged 11?15?years and a comparable non-autistic group (N?=?54) that did not significantly differ on age, sex, nonverbal cognitive ability, or receptive/expressive language skills. Participants were assessed on a video-based spoken narrative task, scored for both overall structure (?story grammar?) and narrative coherence. A battery of tasks measuring mentalising and EF (working memory, inhibition, shifting, generativity) was also administered. Relationships between scores on cognitive measures and narrative performance were investigated using hierarchical linear regression analyses. Mentalising scores were found to significantly predict narrative performance across all outcome measures and were a stronger predictor than diagnostic group. Diagnostic group predicted narrative structure (?story grammar?) scores but not coherence scores. EF scores were not predictive of narrative ability in this sample. Mentalising skills appear to play an important role for both autistic and non-autistic adolescents in the generation of narrative structure and coherence within spoken accounts. En ligne : https://doi.org/10.1002/aur.3272 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546

Orienting to and away from the eyes in infants at high likelihood for autism when scanning faces / Qiandong WANG ; Ying Han ; Yixiao HU ; Xue LI ; Jing LIU ; Hui FANG ; Tianbi LI ; Yanmei Chang ; Li YI in Autism Research, 18-1 (January 2025)  

Public ISBD [article]  inAutism Research > 18-1 (January 2025) . - p.166-178 Titre : Orienting to and away from the eyes in infants at high likelihood for autism when scanning faces : Autism Research Type de document : Texte imprimé et/ou numérique Auteurs : Qiandong WANG, Auteur ; Ying Han, Auteur ; Yixiao HU, Auteur ; Xue LI, Auteur ; Jing LIU, Auteur ; Hui FANG, Auteur ; Tianbi LI, Auteur ; Yanmei Chang, Auteur ; Li YI, Auteur Article en page(s) : p.166-178 Langues : Anglais (eng) Mots-clés : autism  eye movement  face processing  infants  visual attention Index. décimale : PER Périodiques Résumé : Abstract This study employed eye-tracking technology to investigate the mechanisms underlying reduced gaze towards the eyes in infants at high likelihood (HL) for autism, specifically examining whether it results from avoidance triggered by heightened arousal when looking at the eyes or due to indifference to the eyes (i.e., unwilling to orient to the eyes). Infants at HL for autism and typically developing (TD) infants aged within 24?months were tested. In the experiment, participants' gaze was initially guided to the eye or mouth region immediately before the onset of the face. Latency to orient away from the guided regions, latency to orient to the eyes, and the location of the secondary fixation following the onset of the face were measured. The results showed that: (1) The HL infants looked less at eyes than TD infants; (2) Compared with TD infants, HL infants oriented towards eyes more slowly after being guided to the mouth; (3) After being guided to the eyes, HL infants' secondary fixation fell less in the eye region, and their latency to orient away from the eyes was also tended to be shorter. These results suggest that reduced eye-looking time was presented in HL infants, which was further explained by both eye avoidance and indifference to the eyes. Our study contributes theoretically to understanding the atypical face scanning pattern in autistic people and its related underlying mechanisms. Furthermore, our study provides important insights into the development of early screening tools and intervention protocols for autistic people. En ligne : https://doi.org/10.1002/aur.3270 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546 [article] Orienting to and away from the eyes in infants at high likelihood for autism when scanning faces : Autism Research [Texte imprimé et/ou numérique] / Qiandong WANG, Auteur ; Ying Han, Auteur ; Yixiao HU, Auteur ; Xue LI, Auteur ; Jing LIU, Auteur ; Hui FANG, Auteur ; Tianbi LI, Auteur ; Yanmei Chang, Auteur ; Li YI, Auteur . - p.166-178. Langues : Anglais (eng) in Autism Research > 18-1 (January 2025) . - p.166-178 Mots-clés : autism  eye movement  face processing  infants  visual attention Index. décimale : PER Périodiques Résumé : Abstract This study employed eye-tracking technology to investigate the mechanisms underlying reduced gaze towards the eyes in infants at high likelihood (HL) for autism, specifically examining whether it results from avoidance triggered by heightened arousal when looking at the eyes or due to indifference to the eyes (i.e., unwilling to orient to the eyes). Infants at HL for autism and typically developing (TD) infants aged within 24?months were tested. In the experiment, participants' gaze was initially guided to the eye or mouth region immediately before the onset of the face. Latency to orient away from the guided regions, latency to orient to the eyes, and the location of the secondary fixation following the onset of the face were measured. The results showed that: (1) The HL infants looked less at eyes than TD infants; (2) Compared with TD infants, HL infants oriented towards eyes more slowly after being guided to the mouth; (3) After being guided to the eyes, HL infants' secondary fixation fell less in the eye region, and their latency to orient away from the eyes was also tended to be shorter. These results suggest that reduced eye-looking time was presented in HL infants, which was further explained by both eye avoidance and indifference to the eyes. Our study contributes theoretically to understanding the atypical face scanning pattern in autistic people and its related underlying mechanisms. Furthermore, our study provides important insights into the development of early screening tools and intervention protocols for autistic people. En ligne : https://doi.org/10.1002/aur.3270 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546

Children's social preference for teachers versus peers in autism inclusion classrooms: An objective perspective / Madison DRYE ; Chitra BANARJEE ; Lynn Perry ; Alyssa Viggiano ; Dwight Irvin ; Daniel MESSINGER in Autism Research, 18-1 (January 2025)  

Public ISBD [article]  inAutism Research > 18-1 (January 2025) . - p.179-194 Titre : Children's social preference for teachers versus peers in autism inclusion classrooms: An objective perspective : Autism Research Type de document : Texte imprimé et/ou numérique Auteurs : Madison DRYE, Auteur ; Chitra BANARJEE, Auteur ; Lynn Perry, Auteur ; Alyssa Viggiano, Auteur ; Dwight Irvin, Auteur ; Daniel MESSINGER, Auteur Article en page(s) : p.179-194 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  developmental disabilities  inclusion classrooms  objective measurement  social interaction Index. décimale : PER Périodiques Résumé : Abstract In inclusive preschools, children with autism spectrum disorder (ASD) and other developmental disabilities (DD) are less socially engaged with peers than are typically developing (TD) children. However, there is limited objective information describing how children with ASD engage with teachers, or how teacher engagement compares to engagement with peers. We tracked over 750?hours' worth of children's (N?=?77; NASD?=?24, NDD?=?23, NTD?=?30; Mage?=?43.98?months) and teachers' (N?=?12) locations and orientations across eight inclusion preschool classrooms to quantify child-teacher and child-peer social preference. Social approach velocity and time in social contact were computed for each child and compared across social partners to index children's preference for teachers over peers. Children with ASD approached teachers?-but not peers?more quickly than children with TD, and children with ASD were approached more quickly by teachers and more slowly by peers than children with TD. Children with ASD spent less time in social contact with peers and did not differ from children with TD in their time in social contact with teachers. Overall, children with ASD showed a greater preference for approaching, being approached by, and being in social contact with teachers (relative to peers) than children with TD. No significant differences emerged between children with DD and children with TD. In conclusion, children with ASD exhibited a stronger preference for engaging with teachers over peers, re-emphasizing the need for classroom-based interventions that support the peer interactions of children with ASD. En ligne : https://doi.org/10.1002/aur.3276 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546 [article] Children's social preference for teachers versus peers in autism inclusion classrooms: An objective perspective : Autism Research [Texte imprimé et/ou numérique] / Madison DRYE, Auteur ; Chitra BANARJEE, Auteur ; Lynn Perry, Auteur ; Alyssa Viggiano, Auteur ; Dwight Irvin, Auteur ; Daniel MESSINGER, Auteur . - p.179-194. Langues : Anglais (eng) in Autism Research > 18-1 (January 2025) . - p.179-194 Mots-clés : autism spectrum disorder  developmental disabilities  inclusion classrooms  objective measurement  social interaction Index. décimale : PER Périodiques Résumé : Abstract In inclusive preschools, children with autism spectrum disorder (ASD) and other developmental disabilities (DD) are less socially engaged with peers than are typically developing (TD) children. However, there is limited objective information describing how children with ASD engage with teachers, or how teacher engagement compares to engagement with peers. We tracked over 750?hours' worth of children's (N?=?77; NASD?=?24, NDD?=?23, NTD?=?30; Mage?=?43.98?months) and teachers' (N?=?12) locations and orientations across eight inclusion preschool classrooms to quantify child-teacher and child-peer social preference. Social approach velocity and time in social contact were computed for each child and compared across social partners to index children's preference for teachers over peers. Children with ASD approached teachers?-but not peers?more quickly than children with TD, and children with ASD were approached more quickly by teachers and more slowly by peers than children with TD. Children with ASD spent less time in social contact with peers and did not differ from children with TD in their time in social contact with teachers. Overall, children with ASD showed a greater preference for approaching, being approached by, and being in social contact with teachers (relative to peers) than children with TD. No significant differences emerged between children with DD and children with TD. In conclusion, children with ASD exhibited a stronger preference for engaging with teachers over peers, re-emphasizing the need for classroom-based interventions that support the peer interactions of children with ASD. En ligne : https://doi.org/10.1002/aur.3276 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546

Assessing the causal association between celiac disease and autism spectrum disorder: A two-sample Mendelian randomization approach / Abiodun Fatoba ; Claire Simpson in Autism Research, 18-1 (January 2025)  

Public ISBD [article]  inAutism Research > 18-1 (January 2025) . - p.195-201 Titre : Assessing the causal association between celiac disease and autism spectrum disorder: A two-sample Mendelian randomization approach : Autism Research Type de document : Texte imprimé et/ou numérique Auteurs : Abiodun Fatoba, Auteur ; Claire Simpson, Auteur Article en page(s) : p.195-201 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  celiac disease  GWAS  instrument-variables  Mendelian randomization  single nucleotide polymorphisms Index. décimale : PER Périodiques Résumé : Abstract The association between celiac disease (CD) and autism spectrum disorder (ASD) remains inconclusive. Reports from different observational studies have become controversial, necessitating exploration of the causal relationship between CD and ASD. To assess true causality, this study used a two-sample Mendelian randomization (MR) analysis to determine the causal association between CD and ASD. Summary-level data from a genome-wide association study (GWAS) of the European population were used to select instrument variables (IVs) at genome-wide significance (p? En ligne : https://doi.org/10.1002/aur.3257 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546 [article] Assessing the causal association between celiac disease and autism spectrum disorder: A two-sample Mendelian randomization approach : Autism Research [Texte imprimé et/ou numérique] / Abiodun Fatoba, Auteur ; Claire Simpson, Auteur . - p.195-201. Langues : Anglais (eng) in Autism Research > 18-1 (January 2025) . - p.195-201 Mots-clés : autism spectrum disorder  celiac disease  GWAS  instrument-variables  Mendelian randomization  single nucleotide polymorphisms Index. décimale : PER Périodiques Résumé : Abstract The association between celiac disease (CD) and autism spectrum disorder (ASD) remains inconclusive. Reports from different observational studies have become controversial, necessitating exploration of the causal relationship between CD and ASD. To assess true causality, this study used a two-sample Mendelian randomization (MR) analysis to determine the causal association between CD and ASD. Summary-level data from a genome-wide association study (GWAS) of the European population were used to select instrument variables (IVs) at genome-wide significance (p? En ligne : https://doi.org/10.1002/aur.3257 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546

Associations of maternal peripregnancy cannabis use with behavioral and developmental outcomes in children with and without symptoms of autism spectrum disorder: Study to Explore Early Development / Carolyn DIGUISEPPI ; Tessa CRUME ; Brady Holst ; Kaylynn Aiona ; Julia VAN DYKE ; Lisa A. CROEN ; Julie L. DANIELS ; Sandra FRIEDMAN ; Katherine R. SABOURIN ; Laura A. SCHIEVE ; Lisa WIGGINS ; Gayle C. WINDHAM ; Cordelia ROBINSON ROSENBERG in Autism Research, 18-1 (January 2025)  

Public ISBD [article]  inAutism Research > 18-1 (January 2025) . - p.202-216 Titre : Associations of maternal peripregnancy cannabis use with behavioral and developmental outcomes in children with and without symptoms of autism spectrum disorder: Study to Explore Early Development : Autism Research Type de document : Texte imprimé et/ou numérique Auteurs : Carolyn DIGUISEPPI, Auteur ; Tessa CRUME, Auteur ; Brady Holst, Auteur ; Kaylynn Aiona, Auteur ; Julia VAN DYKE, Auteur ; Lisa A. CROEN, Auteur ; Julie L. DANIELS, Auteur ; Sandra FRIEDMAN, Auteur ; Katherine R. SABOURIN, Auteur ; Laura A. SCHIEVE, Auteur ; Lisa WIGGINS, Auteur ; Gayle C. WINDHAM, Auteur ; Cordelia ROBINSON ROSENBERG, Auteur Article en page(s) : p.202-216 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  cannabis  child behavior  child preschool  developmental disabilities  pregnancy  prenatal risk factors  sleep wake disorders Index. décimale : PER Périodiques Résumé : Abstract Some studies report increased prevalence of autism spectrum disorder (ASD) and associated symptoms with prenatal cannabis exposure. We examined whether associations of maternal cannabis use from 3?months preconception through delivery (?peripregnancy?) with behavior and development in the offspring varied with the presence of ASD symptoms. Children ages 30?68?months with ASD symptoms (i.e., met study criteria for ASD or had ASD symptoms on standardized assessments or community ASD diagnosis, N?=?2734) and without ASD symptoms (other developmental delay/disorders or general population sample, N?=?3454) were evaluated with the Child Behavior Checklist and Mullen Scales of Early Learning. We examined cannabis use during three time periods: peripregnancy, pregnancy, and only preconception. Peripregnancy cannabis exposure was reported for 6.0% of children with and 4.6% of children without ASD symptoms. Preconception-only cannabis use (versus no use) was associated with more aggressive behavior, emotional reactivity, and sleep problems in children with ASD symptoms, but not in children without ASD symptoms. Cannabis use during pregnancy was associated with increased attention and sleep problems in children with ASD symptoms; these associations did not differ significantly by ASD symptoms. Peripregnancy cannabis use was not associated with child developmental abilities regardless of ASD symptoms. In summary, associations of peripregnancy cannabis use with some behavioral outcomes differed in children with and without ASD symptoms. With rising cannabis use among pregnant women, future studies that examine a range of developmental risks associated with timing and patterns of cannabis use prior to conception as well as during pregnancy could inform clinical guidance. En ligne : https://doi.org/10.1002/aur.3284 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546 [article] Associations of maternal peripregnancy cannabis use with behavioral and developmental outcomes in children with and without symptoms of autism spectrum disorder: Study to Explore Early Development : Autism Research [Texte imprimé et/ou numérique] / Carolyn DIGUISEPPI, Auteur ; Tessa CRUME, Auteur ; Brady Holst, Auteur ; Kaylynn Aiona, Auteur ; Julia VAN DYKE, Auteur ; Lisa A. CROEN, Auteur ; Julie L. DANIELS, Auteur ; Sandra FRIEDMAN, Auteur ; Katherine R. SABOURIN, Auteur ; Laura A. SCHIEVE, Auteur ; Lisa WIGGINS, Auteur ; Gayle C. WINDHAM, Auteur ; Cordelia ROBINSON ROSENBERG, Auteur . - p.202-216. Langues : Anglais (eng) in Autism Research > 18-1 (January 2025) . - p.202-216 Mots-clés : autism spectrum disorder  cannabis  child behavior  child preschool  developmental disabilities  pregnancy  prenatal risk factors  sleep wake disorders Index. décimale : PER Périodiques Résumé : Abstract Some studies report increased prevalence of autism spectrum disorder (ASD) and associated symptoms with prenatal cannabis exposure. We examined whether associations of maternal cannabis use from 3?months preconception through delivery (?peripregnancy?) with behavior and development in the offspring varied with the presence of ASD symptoms. Children ages 30?68?months with ASD symptoms (i.e., met study criteria for ASD or had ASD symptoms on standardized assessments or community ASD diagnosis, N?=?2734) and without ASD symptoms (other developmental delay/disorders or general population sample, N?=?3454) were evaluated with the Child Behavior Checklist and Mullen Scales of Early Learning. We examined cannabis use during three time periods: peripregnancy, pregnancy, and only preconception. Peripregnancy cannabis exposure was reported for 6.0% of children with and 4.6% of children without ASD symptoms. Preconception-only cannabis use (versus no use) was associated with more aggressive behavior, emotional reactivity, and sleep problems in children with ASD symptoms, but not in children without ASD symptoms. Cannabis use during pregnancy was associated with increased attention and sleep problems in children with ASD symptoms; these associations did not differ significantly by ASD symptoms. Peripregnancy cannabis use was not associated with child developmental abilities regardless of ASD symptoms. In summary, associations of peripregnancy cannabis use with some behavioral outcomes differed in children with and without ASD symptoms. With rising cannabis use among pregnant women, future studies that examine a range of developmental risks associated with timing and patterns of cannabis use prior to conception as well as during pregnancy could inform clinical guidance. En ligne : https://doi.org/10.1002/aur.3284 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546

Relationship between service receipt during the COVID-19 pandemic and autistic children's multisystem outcomes and autism severity: A SPARK dataset analysis / Jung-Mei Tsai ; Anjana BHAT in Autism Research, 18-1 (January 2025)  

Public ISBD [article]  inAutism Research > 18-1 (January 2025) . - p.217-229 Titre : Relationship between service receipt during the COVID-19 pandemic and autistic children's multisystem outcomes and autism severity: A SPARK dataset analysis : Autism Research Type de document : Texte imprimé et/ou numérique Auteurs : Jung-Mei Tsai, Auteur ; Anjana BHAT, Auteur Article en page(s) : p.217-229 Langues : Anglais (eng) Mots-clés : ABA  autism severity  autism spectrum disorder (ASD)  communication  COVID-19  mental health services  OT  PT Index. décimale : PER Périodiques Résumé : Abstract Children with autism spectrum disorder (ASD) display a variety of core and co-occurring difficulties in social, communication, everyday functioning, cognitive, motor, and language domains. Receiving a combination of services to accommodate needs of autistic individuals is essential for improving their future outcomes. During the COVID-19 pandemic, reduced service access negatively impacted autistic children's outcomes. This study aimed to examine the relationship between service receipt and parental perceived outcomes in autistic children while accounting for various demographic, child, and parental factors. We utilized parental COVID-19 impact survey data from the SPARK study (N?=?6067). Ordinal logistic regression analyses were used to predict perceived child outcomes. Demographic, child, and parental factors were included in the prediction models. Service receipt of SLT, ABA, PT/OT, MED, and MH were associated with perceived child outcomes. PT/OT and ABA predicted improvements in domains of social interaction, everyday activity, and overall autism severity; SLT and ABA contributed to improved perceived communication outcomes. Receiving MH and MED services was associated with worsening of perceived outcomes on all domains. Younger age, males, higher family income, lower autism severity, lower motor, function, and cognitive delay, greater language delay, and the absence of parental mental health issues were associated with greater improvements in various perceived outcomes. Overall, PT/OT and ABA services are associated with improved perceived social and functional outcomes whereas SLT and ABA services are associated with improved perceived communication outcomes. We also provide a wholistic view of factors affecting relationships between service receipt and perceived child outcomes during the pandemic. En ligne : https://doi.org/10.1002/aur.3256 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546 [article] Relationship between service receipt during the COVID-19 pandemic and autistic children's multisystem outcomes and autism severity: A SPARK dataset analysis : Autism Research [Texte imprimé et/ou numérique] / Jung-Mei Tsai, Auteur ; Anjana BHAT, Auteur . - p.217-229. Langues : Anglais (eng) in Autism Research > 18-1 (January 2025) . - p.217-229 Mots-clés : ABA  autism severity  autism spectrum disorder (ASD)  communication  COVID-19  mental health services  OT  PT Index. décimale : PER Périodiques Résumé : Abstract Children with autism spectrum disorder (ASD) display a variety of core and co-occurring difficulties in social, communication, everyday functioning, cognitive, motor, and language domains. Receiving a combination of services to accommodate needs of autistic individuals is essential for improving their future outcomes. During the COVID-19 pandemic, reduced service access negatively impacted autistic children's outcomes. This study aimed to examine the relationship between service receipt and parental perceived outcomes in autistic children while accounting for various demographic, child, and parental factors. We utilized parental COVID-19 impact survey data from the SPARK study (N?=?6067). Ordinal logistic regression analyses were used to predict perceived child outcomes. Demographic, child, and parental factors were included in the prediction models. Service receipt of SLT, ABA, PT/OT, MED, and MH were associated with perceived child outcomes. PT/OT and ABA predicted improvements in domains of social interaction, everyday activity, and overall autism severity; SLT and ABA contributed to improved perceived communication outcomes. Receiving MH and MED services was associated with worsening of perceived outcomes on all domains. Younger age, males, higher family income, lower autism severity, lower motor, function, and cognitive delay, greater language delay, and the absence of parental mental health issues were associated with greater improvements in various perceived outcomes. Overall, PT/OT and ABA services are associated with improved perceived social and functional outcomes whereas SLT and ABA services are associated with improved perceived communication outcomes. We also provide a wholistic view of factors affecting relationships between service receipt and perceived child outcomes during the pandemic. En ligne : https://doi.org/10.1002/aur.3256 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=546