Autistic traits in childhood and post-traumatic stress disorder as young adults: a cohort study / Alice M. G. QUINTON in Journal of Child Psychology and Psychiatry, 66-10 (October 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1514-1525 Titre : Autistic traits in childhood and post-traumatic stress disorder as young adults: a cohort study Type de document : texte imprimé Auteurs : Alice M. G. QUINTON, Auteur ; Freya RUMBALL, Auteur ; Angelica RONALD, Auteur ; Helen L. FISHER, Auteur ; Louise ARSENEAULT, Auteur ; Francesca HAPPE, Auteur ; Andrea DANESE, Auteur Article en page(s) : p.1514-1525 Langues : Anglais (eng) Mots-clés : Autism  autism spectrum  trauma  PTSD  psychopathology Index. décimale : PER Périodiques Résumé : Background Despite the higher prevalence of childhood traumatic experiences and post-traumatic stress disorder (PTSD) in autistic adults, research on trauma-related psychopathology and autistic traits in young people is lacking. This study examined if high autistic traits in childhood predispose individuals to traumatic experiences, the development of PTSD and general psychopathology, and greater functional impairment by age 18, in both the general population and a subsample of trauma-exposed young people. Methods Data were utilised from the Environmental Risk (E-Risk) Longitudinal Twin Study, a nationally representative cohort of 2,232 same-sex twins born in 1994 1995 across England and Wales. Participants were a subset of children whose parents completed the Childhood Autism Spectrum Test (CAST), during assessments at ages 8, 9 and/or 12 years (N 1,504). We tested associations between autistic traits in childhood and age-18 reports of lifetime trauma exposure, lifetime PTSD diagnosis, general psychopathology (?p-factor?) and NEET status (?not in employment, education or training?). Analyses were conducted controlling for sex, family socioeconomic status (SES), intelligence quotient (IQ) and accounting for family clustering. Results Higher autistic traits in childhood were significantly associated with greater reports of lifetime trauma exposure (Odd Ratio [OR] 1.26, 95% Confidence Intervals [CI] 1.03; 1.54), lifetime PTSD diagnosis (OR 1.91, 95% CI 1.29; 2.82), general psychopathology (beta 3.22, 95% CI 1.84; 4.60) and NEET status (OR 1.48, 95% CI 1.05; 2.09) at age 18. Only the associations of autistic traits with PTSD and general psychopathology were robust to adjustment for potential confounders. Among trauma-exposed children, autistic traits were also significantly associated with lifetime PTSD diagnosis (OR 1.75, 95% CI 1.15; 2.68) and psychopathology (beta 3.36, 95% CI 0.68; 6.04) at age 18, but only the association with PTSD held when adjusted for confounders. Conclusions Our findings suggest a need to develop targeted assessments and evidence-based treatments for PTSD to meet the needs of children with high autistic traits. However, whether our findings extend to diagnosed autistic children requires further investigation. En ligne : https://doi.org/10.1111/jcpp.14163 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568 [article] Autistic traits in childhood and post-traumatic stress disorder as young adults: a cohort study [texte imprimé] / Alice M. G. QUINTON, Auteur ; Freya RUMBALL, Auteur ; Angelica RONALD, Auteur ; Helen L. FISHER, Auteur ; Louise ARSENEAULT, Auteur ; Francesca HAPPE, Auteur ; Andrea DANESE, Auteur . - p.1514-1525. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-10 (October 2025) . - p.1514-1525 Mots-clés : Autism  autism spectrum  trauma  PTSD  psychopathology Index. décimale : PER Périodiques Résumé : Background Despite the higher prevalence of childhood traumatic experiences and post-traumatic stress disorder (PTSD) in autistic adults, research on trauma-related psychopathology and autistic traits in young people is lacking. This study examined if high autistic traits in childhood predispose individuals to traumatic experiences, the development of PTSD and general psychopathology, and greater functional impairment by age 18, in both the general population and a subsample of trauma-exposed young people. Methods Data were utilised from the Environmental Risk (E-Risk) Longitudinal Twin Study, a nationally representative cohort of 2,232 same-sex twins born in 1994 1995 across England and Wales. Participants were a subset of children whose parents completed the Childhood Autism Spectrum Test (CAST), during assessments at ages 8, 9 and/or 12 years (N 1,504). We tested associations between autistic traits in childhood and age-18 reports of lifetime trauma exposure, lifetime PTSD diagnosis, general psychopathology (?p-factor?) and NEET status (?not in employment, education or training?). Analyses were conducted controlling for sex, family socioeconomic status (SES), intelligence quotient (IQ) and accounting for family clustering. Results Higher autistic traits in childhood were significantly associated with greater reports of lifetime trauma exposure (Odd Ratio [OR] 1.26, 95% Confidence Intervals [CI] 1.03; 1.54), lifetime PTSD diagnosis (OR 1.91, 95% CI 1.29; 2.82), general psychopathology (beta 3.22, 95% CI 1.84; 4.60) and NEET status (OR 1.48, 95% CI 1.05; 2.09) at age 18. Only the associations of autistic traits with PTSD and general psychopathology were robust to adjustment for potential confounders. Among trauma-exposed children, autistic traits were also significantly associated with lifetime PTSD diagnosis (OR 1.75, 95% CI 1.15; 2.68) and psychopathology (beta 3.36, 95% CI 0.68; 6.04) at age 18, but only the association with PTSD held when adjusted for confounders. Conclusions Our findings suggest a need to develop targeted assessments and evidence-based treatments for PTSD to meet the needs of children with high autistic traits. However, whether our findings extend to diagnosed autistic children requires further investigation. En ligne : https://doi.org/10.1111/jcpp.14163 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568

Can a warm and supportive adult protect against mental health problems amongst children with experience of adversity? A twin-differences study / Rebecca E. LACEY ; Louise ARSENEAULT ; Avshalom CASPI ; Eloise CRUSH ; Andrea DANESE ; Rachel M. LATHAM ; Terrie E. MOFFITT ; Joanne B. NEWBURY ; Jonathan D. SCHAEFER ; Helen L. FISHER ; Jessie R. BALDWIN in Journal of Child Psychology and Psychiatry, 66-5 (May 2025)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 66-5 (May 2025) . - p.650-658 Titre : Can a warm and supportive adult protect against mental health problems amongst children with experience of adversity? A twin-differences study Type de document : texte imprimé Auteurs : Rebecca E. LACEY, Auteur ; Louise ARSENEAULT, Auteur ; Avshalom CASPI, Auteur ; Eloise CRUSH, Auteur ; Andrea DANESE, Auteur ; Rachel M. LATHAM, Auteur ; Terrie E. MOFFITT, Auteur ; Joanne B. NEWBURY, Auteur ; Jonathan D. SCHAEFER, Auteur ; Helen L. FISHER, Auteur ; Jessie R. BALDWIN, Auteur Article en page(s) : p.650-658 Langues : Anglais (eng) Mots-clés : Protective factors  ACEs  twin differences  adult social support  maternal warmth  psychopathology  resilience Index. décimale : PER Périodiques Résumé : Background Adverse childhood experiences (ACEs) are associated with mental health problems, but many children who experience ACEs do not develop such difficulties. A warm and supportive adult presence in childhood is associated with a lower likelihood of developing mental health problems after exposure to ACEs. However, it is unclear whether this association is causal, as previous research has not accounted for genetic and environmental confounding. Methods We used the twin-difference design to strengthen causal inference about whether a warm and supportive adult presence protects children exposed to ACEs from mental health problems. Participants were from the Environmental Risk (E-Risk) Longitudinal Twin Study, a UK population-representative birth cohort of 2,232 same-sex twins. ACEs were measured prospectively from ages 5 to 12. Maternal warmth was assessed at ages 5 and 10 through maternal speech samples. Adult support was assessed through child reports at age 12. Mental health problems were assessed through interviews at age 12 with parents and teachers and participants at age 18. Results Among children exposed to ACEs, those who experienced greater maternal warmth and adult support had lower levels of mental health problems at ages 12 and 18. In monozygotic twin-difference analyses, the protective effects of maternal warmth and adult support on mental health were attenuated by 70% for maternal warmth and 81% for adult support, compared to phenotypic analyses. Twins who experienced greater maternal warmth and adult support had minimal or no difference in mental health compared to their co-twins, concordant for ACE exposure. Conclusions The apparent protective effect of a warm, supportive adult against mental health problems following ACEs is largely explained by genetic and environmental confounding. This suggests that interventions which boost maternal warmth and adult support should be supplemented by components addressing wider family environments and heritable vulnerabilities in children exposed to adversity, to improve mental health. En ligne : https://doi.org/10.1111/jcpp.14070 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=554 [article] Can a warm and supportive adult protect against mental health problems amongst children with experience of adversity? A twin-differences study [texte imprimé] / Rebecca E. LACEY, Auteur ; Louise ARSENEAULT, Auteur ; Avshalom CASPI, Auteur ; Eloise CRUSH, Auteur ; Andrea DANESE, Auteur ; Rachel M. LATHAM, Auteur ; Terrie E. MOFFITT, Auteur ; Joanne B. NEWBURY, Auteur ; Jonathan D. SCHAEFER, Auteur ; Helen L. FISHER, Auteur ; Jessie R. BALDWIN, Auteur . - p.650-658. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 66-5 (May 2025) . - p.650-658 Mots-clés : Protective factors  ACEs  twin differences  adult social support  maternal warmth  psychopathology  resilience Index. décimale : PER Périodiques Résumé : Background Adverse childhood experiences (ACEs) are associated with mental health problems, but many children who experience ACEs do not develop such difficulties. A warm and supportive adult presence in childhood is associated with a lower likelihood of developing mental health problems after exposure to ACEs. However, it is unclear whether this association is causal, as previous research has not accounted for genetic and environmental confounding. Methods We used the twin-difference design to strengthen causal inference about whether a warm and supportive adult presence protects children exposed to ACEs from mental health problems. Participants were from the Environmental Risk (E-Risk) Longitudinal Twin Study, a UK population-representative birth cohort of 2,232 same-sex twins. ACEs were measured prospectively from ages 5 to 12. Maternal warmth was assessed at ages 5 and 10 through maternal speech samples. Adult support was assessed through child reports at age 12. Mental health problems were assessed through interviews at age 12 with parents and teachers and participants at age 18. Results Among children exposed to ACEs, those who experienced greater maternal warmth and adult support had lower levels of mental health problems at ages 12 and 18. In monozygotic twin-difference analyses, the protective effects of maternal warmth and adult support on mental health were attenuated by 70% for maternal warmth and 81% for adult support, compared to phenotypic analyses. Twins who experienced greater maternal warmth and adult support had minimal or no difference in mental health compared to their co-twins, concordant for ACE exposure. Conclusions The apparent protective effect of a warm, supportive adult against mental health problems following ACEs is largely explained by genetic and environmental confounding. This suggests that interventions which boost maternal warmth and adult support should be supplemented by components addressing wider family environments and heritable vulnerabilities in children exposed to adversity, to improve mental health. En ligne : https://doi.org/10.1111/jcpp.14070 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=554

Editorial: Salutogenic mental health science-A phoenix rising from the pathogenic ashes of psychiatry? / Helen L. FISHER in Journal of Child Psychology and Psychiatry, 64-11 (November 2023)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 64-11 (November 2023) . - p.1529-1531 Titre : Editorial: Salutogenic mental health science-A phoenix rising from the pathogenic ashes of psychiatry? Type de document : texte imprimé Auteurs : Helen L. FISHER, Auteur Article en page(s) : p.1529-1531 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : As highlighted by several of the papers featured in this current issue of the Journal, psychiatric research and practice is dominated by a pathogenic focus on understanding the origins of mental ill-health and developing interventions to prevent or treat psychopathology. The World Health Organization has called for a paradigm shift to move away from the almost exclusive focus on the absence of illness towards the promotion of mental, physical and social well-being among those with or at risk of psychiatric disorders. Adoption of a salutogenic approach, which focuses on factors and interventions that promote positive health and improve quality of life, has been heralded as the transformation psychiatry requires to achieve this ambitious aim. Looking forward, salutogenic mental health science should harness the power of longitudinal data and analytical techniques, centre lived experience expertise, and take heed of the cautionary tales of its pathogenic predecessor. En ligne : https://doi.org/10.1111/jcpp.13890 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=512 [article] Editorial: Salutogenic mental health science-A phoenix rising from the pathogenic ashes of psychiatry? [texte imprimé] / Helen L. FISHER, Auteur . - p.1529-1531. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 64-11 (November 2023) . - p.1529-1531 Index. décimale : PER Périodiques Résumé : As highlighted by several of the papers featured in this current issue of the Journal, psychiatric research and practice is dominated by a pathogenic focus on understanding the origins of mental ill-health and developing interventions to prevent or treat psychopathology. The World Health Organization has called for a paradigm shift to move away from the almost exclusive focus on the absence of illness towards the promotion of mental, physical and social well-being among those with or at risk of psychiatric disorders. Adoption of a salutogenic approach, which focuses on factors and interventions that promote positive health and improve quality of life, has been heralded as the transformation psychiatry requires to achieve this ambitious aim. Looking forward, salutogenic mental health science should harness the power of longitudinal data and analytical techniques, centre lived experience expertise, and take heed of the cautionary tales of its pathogenic predecessor. En ligne : https://doi.org/10.1111/jcpp.13890 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=512

Editorial: The near ubiquity of comorbidity - what are the implications for children's mental health research and practice? / Helen L. FISHER in Journal of Child Psychology and Psychiatry, 63-5 (May 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-5 (May 2022) . - p.505-506 Titre : Editorial: The near ubiquity of comorbidity - what are the implications for children's mental health research and practice? Type de document : texte imprimé Auteurs : Helen L. FISHER, Auteur Article en page(s) : p.505-506 Langues : Anglais (eng) Mots-clés : Adult  Child  Child Health  Comorbidity  Humans  Mental Disorders/epidemiology/psychology  Mental Health  Psychopathology  integrated care  learning disorders  neurodevelopmental Index. décimale : PER Périodiques Résumé : The experience of two or more mental health disorders or symptom-clusters, either simultaneously or sequentially, is common among adults. Increasing evidence suggests that such comorbidity may also be prevalent among children though it often extends beyond mental health disorders. This is highlighted by several of the papers featured in the current issue of the Journal, which are summarised in this editorial. These studies underscore the importance of providing integrated care for children to ensure all their needs are effectively addressed. It also raises questions about the distinctions we draw between disorders and supports calls for dimensional approaches to conceptualising psychopathology and its inter-relatedness with other aspects of health and functioning. En ligne : http://dx.doi.org/10.1111/jcpp.13612 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=476 [article] Editorial: The near ubiquity of comorbidity - what are the implications for children's mental health research and practice? [texte imprimé] / Helen L. FISHER, Auteur . - p.505-506. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-5 (May 2022) . - p.505-506 Mots-clés : Adult  Child  Child Health  Comorbidity  Humans  Mental Disorders/epidemiology/psychology  Mental Health  Psychopathology  integrated care  learning disorders  neurodevelopmental Index. décimale : PER Périodiques Résumé : The experience of two or more mental health disorders or symptom-clusters, either simultaneously or sequentially, is common among adults. Increasing evidence suggests that such comorbidity may also be prevalent among children though it often extends beyond mental health disorders. This is highlighted by several of the papers featured in the current issue of the Journal, which are summarised in this editorial. These studies underscore the importance of providing integrated care for children to ensure all their needs are effectively addressed. It also raises questions about the distinctions we draw between disorders and supports calls for dimensional approaches to conceptualising psychopathology and its inter-relatedness with other aspects of health and functioning. En ligne : http://dx.doi.org/10.1111/jcpp.13612 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=476

Externalizing the threat from within: A new direction for researching associations between suicide and psychotic experiences / Jamie MURPHY in Development and Psychopathology, 34-3 (August 2022)  

Public ISBD [article]  inDevelopment and Psychopathology > 34-3 (August 2022) . - p.1034-1044 Titre : Externalizing the threat from within: A new direction for researching associations between suicide and psychotic experiences Type de document : texte imprimé Auteurs : Jamie MURPHY, Auteur ; Mark SHEVLIN, Auteur ; Louise ARSENEAULT, Auteur ; Richard BENTALL, Auteur ; Avshalom CASPI, Auteur ; Andrea DANESE, Auteur ; Philip HYLAND, Auteur ; Terrie E. MOFFITT, Auteur ; Helen L. FISHER, Auteur Article en page(s) : p.1034-1044 Langues : Anglais (eng) Mots-clés : birth-cohort  cross-lagged panel analysis  psychosis  self-harm  self-injurious behavior Index. décimale : PER Périodiques Résumé : A recent suicidal drive hypothesis posits that psychotic experiences (PEs) may serve to externalize internally generated and self-directed threat (i.e., self-injurious/suicidal behavior [SIB]) in order to optimize survival; however, it must first be demonstrated that such internal threat can both precede and inform PEs. The current study conducted the first known bidirectional analysis of SIB and PEs to test whether SIB could be considered as a plausible antecedent for PEs. Prospective data were utilized from the Environmental Risk (E-Risk) Longitudinal Twin Study, a nationally representative birth cohort of 2232 twins, that captured SIB (any self-harm or suicidal attempt) and PEs at ages 12 and 18 years. Cross-lagged panel models demonstrated that the association between SIB at age 12 and PEs at age 18 was as strong as the association between PEs at age 12 and SIB at age 18. Indeed, the best representation of the data was a model where these paths were constrained to be equal (OR = 2.48, 95% CI = 1.63 “3.79). Clinical interview case notes for those who reported both SIB and PEs at age 18, revealed that PEs were explicitly characterized by SIB/threat/death-related content for 39% of cases. These findings justify further investigation of the suicidal drive hypothesis. En ligne : http://dx.doi.org/10.1017/S0954579420001728 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=485 [article] Externalizing the threat from within: A new direction for researching associations between suicide and psychotic experiences [texte imprimé] / Jamie MURPHY, Auteur ; Mark SHEVLIN, Auteur ; Louise ARSENEAULT, Auteur ; Richard BENTALL, Auteur ; Avshalom CASPI, Auteur ; Andrea DANESE, Auteur ; Philip HYLAND, Auteur ; Terrie E. MOFFITT, Auteur ; Helen L. FISHER, Auteur . - p.1034-1044. Langues : Anglais (eng) in Development and Psychopathology > 34-3 (August 2022) . - p.1034-1044 Mots-clés : birth-cohort  cross-lagged panel analysis  psychosis  self-harm  self-injurious behavior Index. décimale : PER Périodiques Résumé : A recent suicidal drive hypothesis posits that psychotic experiences (PEs) may serve to externalize internally generated and self-directed threat (i.e., self-injurious/suicidal behavior [SIB]) in order to optimize survival; however, it must first be demonstrated that such internal threat can both precede and inform PEs. The current study conducted the first known bidirectional analysis of SIB and PEs to test whether SIB could be considered as a plausible antecedent for PEs. Prospective data were utilized from the Environmental Risk (E-Risk) Longitudinal Twin Study, a nationally representative birth cohort of 2232 twins, that captured SIB (any self-harm or suicidal attempt) and PEs at ages 12 and 18 years. Cross-lagged panel models demonstrated that the association between SIB at age 12 and PEs at age 18 was as strong as the association between PEs at age 12 and SIB at age 18. Indeed, the best representation of the data was a model where these paths were constrained to be equal (OR = 2.48, 95% CI = 1.63 “3.79). Clinical interview case notes for those who reported both SIB and PEs at age 18, revealed that PEs were explicitly characterized by SIB/threat/death-related content for 39% of cases. These findings justify further investigation of the suicidal drive hypothesis. En ligne : http://dx.doi.org/10.1017/S0954579420001728 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=485

In the eye of the beholder: Perceptions of neighborhood adversity and psychotic experiences in adolescence / Joanne B. NEWBURY in Development and Psychopathology, 29-5 (December 2017)  

Permalink

A longitudinal twin study of victimization and loneliness from childhood to young adulthood / Timothy MATTHEWS in Development and Psychopathology, 34-1 (February 2022)  

Permalink

Measuring adolescents' exposure to victimization: The Environmental Risk (E-Risk) Longitudinal Twin Study / Helen L. FISHER in Development and Psychopathology, 27-4 (Part 2) (November 2015)  

Permalink

The developmental interplay between the p-factor of psychopathology and the g-factor of intelligence from age 7 through 16 years / Sophie VON STUMM in Development and Psychopathology, 36-3 (August 2024)  

Permalink

The relationship between type, timing and duration of exposure to adverse childhood experiences and adolescent self-harm and depression: findings from three UK prospective population-based cohorts / Abigail E. RUSSELL ; Laura D. HOWE ; Annie HERBERT ; Andrew D. A. C. SMITH ; Helen L. FISHER ; Jessie R. BALDWIN ; Louise ARSENEAULT ; Andrea DANESE ; Becky MARS in Journal of Child Psychology and Psychiatry, 65-10 (October 2024)  

Permalink

---

1 (1 - 10 / 10) Par page : 25 50 100 200