Brief Report: Methods for Acquiring Structural MRI Data in Very Young Children with Autism Without the Use of Sedation / Christine W. NORDAHL in Journal of Autism and Developmental Disorders, 38-8 (September 2008)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 38-8 (September 2008) . - p.1581-1590 Titre : Brief Report: Methods for Acquiring Structural MRI Data in Very Young Children with Autism Without the Use of Sedation Type de document : texte imprimé Auteurs : Christine W. NORDAHL, Auteur ; David G. AMARAL, Auteur ; Marjorie SOLOMON, Auteur ; Tony J. SIMON, Auteur ; Cynthia ZIERHUT, Auteur ; Sally J. ROGERS, Auteur Année de publication : 2008 Article en page(s) : p.1581-1590 Langues : Anglais (eng) Mots-clés : MRI Autism Natural-sleep Sedation Children Toddlers Index. décimale : PER Périodiques Résumé : We describe a protocol with which we achieved a 93% success rate in acquiring high quality MRI scans without the use of sedation in 2.5–4.5 year old children with autism, developmental delays, and typical development. Our main strategy was to conduct MRIs during natural nocturnal sleep in the evenings after the child’s normal bedtime. Alternatively, with some older and higher functioning children, the MRI was conducted while the child was awake and watching a video. Both strategies relied heavily on the creation of a child and family friendly MRI environment and the involvement of parents as collaborators in the project. Scanning very young children with autism, typical development, and developmental delays without the use of sedation or anesthesia was possible in the majority of cases. En ligne : http://dx.doi.org/10.1007/s10803-007-0514-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=539 [article] Brief Report: Methods for Acquiring Structural MRI Data in Very Young Children with Autism Without the Use of Sedation [texte imprimé] / Christine W. NORDAHL, Auteur ; David G. AMARAL, Auteur ; Marjorie SOLOMON, Auteur ; Tony J. SIMON, Auteur ; Cynthia ZIERHUT, Auteur ; Sally J. ROGERS, Auteur . - 2008 . - p.1581-1590. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 38-8 (September 2008) . - p.1581-1590 Mots-clés : MRI Autism Natural-sleep Sedation Children Toddlers Index. décimale : PER Périodiques Résumé : We describe a protocol with which we achieved a 93% success rate in acquiring high quality MRI scans without the use of sedation in 2.5–4.5 year old children with autism, developmental delays, and typical development. Our main strategy was to conduct MRIs during natural nocturnal sleep in the evenings after the child’s normal bedtime. Alternatively, with some older and higher functioning children, the MRI was conducted while the child was awake and watching a video. Both strategies relied heavily on the creation of a child and family friendly MRI environment and the involvement of parents as collaborators in the project. Scanning very young children with autism, typical development, and developmental delays without the use of sedation or anesthesia was possible in the majority of cases. En ligne : http://dx.doi.org/10.1007/s10803-007-0514-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=539

Changes in the severity of autism symptom domains are related to mental health challenges during middle childhood / Einat WAIZBARD-BARTOV in Autism, 28-5 (May 2024)  

Public ISBD [article]  inAutism > 28-5 (May 2024) . - p.1216-1230 Titre : Changes in the severity of autism symptom domains are related to mental health challenges during middle childhood Type de document : texte imprimé Auteurs : Einat WAIZBARD-BARTOV, Auteur ; Emilio FERRER, Auteur ; Brianna HEATH, Auteur ; Derek S. ANDREWS, Auteur ; Sally J. ROGERS, Auteur ; Connor M. KERNS, Auteur ; Christine W. NORDAHL, Auteur ; Marjorie SOLOMON, Auteur ; David G. AMARAL, Auteur Article en page(s) : p.1216-1230 Langues : Anglais (eng) Mots-clés : anxiety  attention-deficit hyperactivity disorder  autism spectrum disorders  behavioral measurement  development  psychiatric comorbidity  repetitive behaviors and interests  school-age children  social cognition and social behavior Index. décimale : PER Périodiques Résumé : Many autistic children experience changes in core symptom severity across middle childhood, when co-occurring mental health conditions emerge. We evaluated this relationship in 75 autistic children from 6 to 11 years old. Autism symptom severity change was evaluated for total autism symptoms using the autism diagnostic observation schedule calibrated severity score, as well as social-communication symptoms calibrated severity score, and restricted/repetitive behaviors calibrated severity score. Children were grouped based on their symptom severity change patterns. Mental health symptoms (attention-deficit hyperactivity disorder, anxiety, disruptive behavior problems) were assessed via parental interview and questionnaire and compared across the groups. Co-occurring mental health symptoms were more strongly associated with change in social-communication symptom or restricted/repetitive behavior severity than with total autism symptom severity. Two relevant groups were identified. The social-communication symptom-increasing-severity-group (21.3%) had elevated and increasing levels of anxiety, attention-deficit hyperactivity disorder, and disruptive behavior problems compared with children with stable social-communication symptom severity. The restricted/repetitive behavior-decreasing-severity-group (22.7%) had elevated and increasing levels of anxiety; 94% of these children met criteria for an anxiety disorder. Autism symptom severity change during middle childhood is associated with co-occurring mental health symptoms. Children that increase in social-communication symptom severity are also likely to demonstrate greater psychopathology, while decreases in restricted/repetitive behavior severity are associated with higher levels of anxiety. Lay abstract For many autistic children, the severity of their autism symptoms changes during middle childhood. We studied whether these changes are associated with the emergence of other mental health challenges such as anxiety and attention-deficit hyperactivity disorder. Children who had increased social-communication challenges had more anxiety and attention-deficit hyperactivity disorder symptoms and disruptive behavior problems than other children. Children who decreased their restricted and repetitive behaviors, on the contrary, had more anxiety. We discuss why these changes in autism symptoms may lead to increases in other mental health concerns. En ligne : https://dx.doi.org/10.1177/13623613231195108 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=527 [article] Changes in the severity of autism symptom domains are related to mental health challenges during middle childhood [texte imprimé] / Einat WAIZBARD-BARTOV, Auteur ; Emilio FERRER, Auteur ; Brianna HEATH, Auteur ; Derek S. ANDREWS, Auteur ; Sally J. ROGERS, Auteur ; Connor M. KERNS, Auteur ; Christine W. NORDAHL, Auteur ; Marjorie SOLOMON, Auteur ; David G. AMARAL, Auteur . - p.1216-1230. Langues : Anglais (eng) in Autism > 28-5 (May 2024) . - p.1216-1230 Mots-clés : anxiety  attention-deficit hyperactivity disorder  autism spectrum disorders  behavioral measurement  development  psychiatric comorbidity  repetitive behaviors and interests  school-age children  social cognition and social behavior Index. décimale : PER Périodiques Résumé : Many autistic children experience changes in core symptom severity across middle childhood, when co-occurring mental health conditions emerge. We evaluated this relationship in 75 autistic children from 6 to 11 years old. Autism symptom severity change was evaluated for total autism symptoms using the autism diagnostic observation schedule calibrated severity score, as well as social-communication symptoms calibrated severity score, and restricted/repetitive behaviors calibrated severity score. Children were grouped based on their symptom severity change patterns. Mental health symptoms (attention-deficit hyperactivity disorder, anxiety, disruptive behavior problems) were assessed via parental interview and questionnaire and compared across the groups. Co-occurring mental health symptoms were more strongly associated with change in social-communication symptom or restricted/repetitive behavior severity than with total autism symptom severity. Two relevant groups were identified. The social-communication symptom-increasing-severity-group (21.3%) had elevated and increasing levels of anxiety, attention-deficit hyperactivity disorder, and disruptive behavior problems compared with children with stable social-communication symptom severity. The restricted/repetitive behavior-decreasing-severity-group (22.7%) had elevated and increasing levels of anxiety; 94% of these children met criteria for an anxiety disorder. Autism symptom severity change during middle childhood is associated with co-occurring mental health symptoms. Children that increase in social-communication symptom severity are also likely to demonstrate greater psychopathology, while decreases in restricted/repetitive behavior severity are associated with higher levels of anxiety. Lay abstract For many autistic children, the severity of their autism symptoms changes during middle childhood. We studied whether these changes are associated with the emergence of other mental health challenges such as anxiety and attention-deficit hyperactivity disorder. Children who had increased social-communication challenges had more anxiety and attention-deficit hyperactivity disorder symptoms and disruptive behavior problems than other children. Children who decreased their restricted and repetitive behaviors, on the contrary, had more anxiety. We discuss why these changes in autism symptoms may lead to increases in other mental health concerns. En ligne : https://dx.doi.org/10.1177/13623613231195108 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=527

Children with ASD Show Impaired Item-Space Recollection, But Preserved Item-Color Recollection / Lindsey N. MOONEY in Autism Research, 13-11 (November 2020)  

Public ISBD [article]  inAutism Research > 13-11 (November 2020) . - p.1985-1997 Titre : Children with ASD Show Impaired Item-Space Recollection, But Preserved Item-Color Recollection Type de document : texte imprimé Auteurs : Lindsey N. MOONEY, Auteur ; Christine W. NORDAHL, Auteur ; Marjorie SOLOMON, Auteur ; Simona GHETTI, Auteur Article en page(s) : p.1985-1997 Langues : Anglais (eng) Mots-clés : Asd  episodic memory  global processing  middle childhood  signal detection theory Index. décimale : PER Périodiques Résumé : Although individuals with autism spectrum disorder (ASD) have been often shown to display similar memory performance on semantic memory tasks compared to typically developing (TD) children, there is ongoing debate about whether and how their ability to remember specific past events (i.e., episodic memory) is impaired. We assessed a sample of 62 children with ASD and 72 TD children, ranging in age between 8 and 12 years on 2 memory tasks. Participants encoded a series of images and their association with either where they appeared on the screen (item-space association task) or with the color of an image's border (item-color association task). Children with ASD showed worse memory in the item-space association task compared to their TD peers, but comparable memory for the item-color association task. These differences persisted when age, intellectual quotient, and general item recognition memory were accounted for statistically. We interpret these results in light of evidence for specific deficits along the dorsal stream affecting processing of spatiotemporal information in ASD. Autism Res 2020, 13: 1985-1997. © 2020 International Society for Autism Research and Wiley Periodicals LLC LAY SUMMARY: Episodic memory requires the ability to bind contextual details (such as color, location, etc.) to an item or event in order to remember the past with specific detail. Here, we compared children with autism spectrum disorder (ASD) and typically developing (TD) children on tasks examining episodic memory. Children with ASD recalled more poorly previously seen items and their associated space-related details, but they performed comparably to TD children on color details. We discuss the possible mechanisms that contribute to worse spatial processing/recall in ASD. En ligne : http://dx.doi.org/10.1002/aur.2394 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] Children with ASD Show Impaired Item-Space Recollection, But Preserved Item-Color Recollection [texte imprimé] / Lindsey N. MOONEY, Auteur ; Christine W. NORDAHL, Auteur ; Marjorie SOLOMON, Auteur ; Simona GHETTI, Auteur . - p.1985-1997. Langues : Anglais (eng) in Autism Research > 13-11 (November 2020) . - p.1985-1997 Mots-clés : Asd  episodic memory  global processing  middle childhood  signal detection theory Index. décimale : PER Périodiques Résumé : Although individuals with autism spectrum disorder (ASD) have been often shown to display similar memory performance on semantic memory tasks compared to typically developing (TD) children, there is ongoing debate about whether and how their ability to remember specific past events (i.e., episodic memory) is impaired. We assessed a sample of 62 children with ASD and 72 TD children, ranging in age between 8 and 12 years on 2 memory tasks. Participants encoded a series of images and their association with either where they appeared on the screen (item-space association task) or with the color of an image's border (item-color association task). Children with ASD showed worse memory in the item-space association task compared to their TD peers, but comparable memory for the item-color association task. These differences persisted when age, intellectual quotient, and general item recognition memory were accounted for statistically. We interpret these results in light of evidence for specific deficits along the dorsal stream affecting processing of spatiotemporal information in ASD. Autism Res 2020, 13: 1985-1997. © 2020 International Society for Autism Research and Wiley Periodicals LLC LAY SUMMARY: Episodic memory requires the ability to bind contextual details (such as color, location, etc.) to an item or event in order to remember the past with specific detail. Here, we compared children with autism spectrum disorder (ASD) and typically developing (TD) children on tasks examining episodic memory. Children with ASD recalled more poorly previously seen items and their associated space-related details, but they performed comparably to TD children on color details. We discuss the possible mechanisms that contribute to worse spatial processing/recall in ASD. En ligne : http://dx.doi.org/10.1002/aur.2394 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

Commentary: 'Camouflaging' in autistic people - reflection on Fombonne (2020) / Meng-Chuan LAI in Journal of Child Psychology and Psychiatry, 62-8 (August 2021)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 62-8 (August 2021) Titre : Commentary: 'Camouflaging' in autistic people - reflection on Fombonne (2020) Type de document : texte imprimé Auteurs : Meng-Chuan LAI, Auteur ; Laura HULL, Auteur ; William MANDY, Auteur ; Bhismadev CHAKRABARTI, Auteur ; Christine W. NORDAHL, Auteur ; Michael V. LOMBARDO, Auteur ; Stephanie H. AMEIS, Auteur ; Peter SZATMARI, Auteur ; Simon BARON-COHEN, Auteur ; Francesca HAPPE, Auteur ; Lucy A. LIVINGSTON, Auteur Langues : Anglais (eng) Mots-clés : Adaptation, Psychological  Adult  Autistic Disorder  Female  Humans Index. décimale : PER Périodiques Résumé : Fombonne's (2020) editorial is a thought-provoking appraisal of the literature on 'camouflaging', whereby some autistic people mask or compensate for their autistic characteristics as an attempt to fit in and to cope with disabilities under neurotypical social norms. Fombonne (2020) highlights three issues of contention: (a) construct validity and measurement of camouflaging; (b) camouflaging as a reason for late autism diagnosis in adolescence/adulthood; and (c) camouflaging as a feature of the 'female autism phenotype'. Here, we argue that (a) establishing construct validity and measurement of different aspects of camouflaging is warranted; (b) subjective experiences are important for the differential diagnosis of autism in adolescence/adulthood; and (c) camouflaging is not necessarily a feature of autism in female individuals - nevertheless, taking into account sex and gender influences in development is crucial to understand behavioural manifestations of autism. Future research and clinical directions should involve clarification of associated constructs and measurements, demography, mechanisms, impact (including harms and benefits) and tailored support. En ligne : http://dx.doi.org/10.1111/jcpp.13344 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456 [article] Commentary: 'Camouflaging' in autistic people - reflection on Fombonne (2020) [texte imprimé] / Meng-Chuan LAI, Auteur ; Laura HULL, Auteur ; William MANDY, Auteur ; Bhismadev CHAKRABARTI, Auteur ; Christine W. NORDAHL, Auteur ; Michael V. LOMBARDO, Auteur ; Stephanie H. AMEIS, Auteur ; Peter SZATMARI, Auteur ; Simon BARON-COHEN, Auteur ; Francesca HAPPE, Auteur ; Lucy A. LIVINGSTON, Auteur. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 62-8 (August 2021) Mots-clés : Adaptation, Psychological  Adult  Autistic Disorder  Female  Humans Index. décimale : PER Périodiques Résumé : Fombonne's (2020) editorial is a thought-provoking appraisal of the literature on 'camouflaging', whereby some autistic people mask or compensate for their autistic characteristics as an attempt to fit in and to cope with disabilities under neurotypical social norms. Fombonne (2020) highlights three issues of contention: (a) construct validity and measurement of camouflaging; (b) camouflaging as a reason for late autism diagnosis in adolescence/adulthood; and (c) camouflaging as a feature of the 'female autism phenotype'. Here, we argue that (a) establishing construct validity and measurement of different aspects of camouflaging is warranted; (b) subjective experiences are important for the differential diagnosis of autism in adolescence/adulthood; and (c) camouflaging is not necessarily a feature of autism in female individuals - nevertheless, taking into account sex and gender influences in development is crucial to understand behavioural manifestations of autism. Future research and clinical directions should involve clarification of associated constructs and measurements, demography, mechanisms, impact (including harms and benefits) and tailored support. En ligne : http://dx.doi.org/10.1111/jcpp.13344 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=456

Correction: Video Game Use, Aggression, and Social Impairment in Adolescents with Autism Spectrum Disorder / Konnor DAVIS in Journal of Autism and Developmental Disorders, 53-3 (March 2023)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 53-3 (March 2023) . - p.1301-1301 Titre : Correction: Video Game Use, Aggression, and Social Impairment in Adolescents with Autism Spectrum Disorder Type de document : texte imprimé Auteurs : Konnor DAVIS, Auteur ; Ana-Maria IOSIF, Auteur ; Christine W. NORDAHL, Auteur ; Marjorie SOLOMON, Auteur ; Marie K. KRUG, Auteur Article en page(s) : p.1301-1301 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : https://doi.org/10.1007/s10803-022-05694-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=500 [article] Correction: Video Game Use, Aggression, and Social Impairment in Adolescents with Autism Spectrum Disorder [texte imprimé] / Konnor DAVIS, Auteur ; Ana-Maria IOSIF, Auteur ; Christine W. NORDAHL, Auteur ; Marjorie SOLOMON, Auteur ; Marie K. KRUG, Auteur . - p.1301-1301. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 53-3 (March 2023) . - p.1301-1301 Index. décimale : PER Périodiques En ligne : https://doi.org/10.1007/s10803-022-05694-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=500

Cortical Thickness Differences in Autistic Children With and Without Intellectual Disability / Derek S. ANDREWS in Autism Research, 18-3 (March 2025)  

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Developmental-behavioral profiles in children with autism spectrum disorder and co-occurring gastrointestinal symptoms / Bibiana RESTREPO in Autism Research, 13-10 (October 2020)  

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Differential Altered Auditory Event-Related Potential Responses in Young Boys on the Autism Spectrum With and Without Disproportionate Megalencephaly / Rosanna DE MEO-MONTEIL in Autism Research, 12-8 (August 2019)  

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Erratum: Sex differences in the corpus callosum in preschool-aged children with autism spectrum disorder / Christine W. NORDAHL in Molecular Autism, (June 2015)  

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Evidence for differential alternative splicing in blood of young boys with autism spectrum disorders / Boryana STAMOVA in Molecular Autism, (September 2013)  

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Eye-Tracking Reveals Absent Repetition Learning Across the Autism Spectrum: Evidence From a Passive Viewing Task / Sebastian B. GAIGG in Autism Research, 13-11 (November 2020)  

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Factor Structure of the Children's Sleep Habits Questionnaire in Young Children with and Without Autism / Burt HATCH in Journal of Autism and Developmental Disorders, 51-9 (September 2021)  

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Fear Potentiated Startle in Children With Autism Spectrum Disorder: Association With Anxiety Symptoms and Amygdala Volume / David HESSL in Autism Research, 14-3 (March 2021)  

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Hyper-focus, sticky attention, and springy attention in young autistic children: Associations with sensory behaviors and cognitive ability / Andre SILLAS ; Melanie PRIETO ; Emily CAMP ; Christine W. NORDAHL ; Susan M. RIVERA in Autism Research, 17-8 (August 2024)  

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Hypothalamic volume is associated with dysregulated sleep in autistic and non-autistic young children / Burt HATCH in Autism, 29-11 (November 2025)  

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