Development and validation of an Arabic language eye-tracking paradigm for the early screening and diagnosis of autism spectrum disorders in Qatar / Iman GHAZAL ; I. Richard THOMPSON ; Eric W. KLINGEMIER ; Mohammed ALDOSARI ; Hawraa AL-SHAMMARI ; Fatema AL-FARAJ ; Saba EL-HAG ; Mohamed TOLEFAT ; Mogahed ALI ; Bisher NASIR ; Thomas W. FRAZIER in Autism Research, 16-12 (December 2023)  

Public ISBD [article]  inAutism Research > 16-12 (December 2023) . - p.2291-2301 Titre : Development and validation of an Arabic language eye-tracking paradigm for the early screening and diagnosis of autism spectrum disorders in Qatar Type de document : texte imprimé Auteurs : Iman GHAZAL, Auteur ; I. Richard THOMPSON, Auteur ; Eric W. KLINGEMIER, Auteur ; Mohammed ALDOSARI, Auteur ; Hawraa AL-SHAMMARI, Auteur ; Fatema AL-FARAJ, Auteur ; Saba EL-HAG, Auteur ; Mohamed TOLEFAT, Auteur ; Mogahed ALI, Auteur ; Bisher NASIR, Auteur ; Thomas W. FRAZIER, Auteur Article en page(s) : p.2291-2301 Index. décimale : PER Périodiques Résumé : Abstract Abnormal eye gaze is a hallmark characteristic of autism spectrum disorder (ASD). The primary aim of the present research was to develop an Arabic version of an objective measure of ASD, the "autism index" (AI), based on eye gaze tracking to social and nonsocial stimuli validated initially in the United States. The initial phase of this study included the translation of English language eye-tracking stimuli into stimuli appropriate for an Arabic-speaking culture. During the second phase, we tested it on a total of 144 children with ASD, and 96 controls. The AI had excellent internal consistency and test-retest reliability. Moreover, the AI showed good differentiation of ASD from control cases (AUC = 0.730, SE = 0.035). The AI was significantly positively correlated with SCQ total raw scores (r = 0.46, p<0.001). ADOS-2 scores were only available in the ASD group and did not show a significant relationship with AI scores (r = 0.10, p = 0.348), likely due to the restricted range. The AI, when implemented using Arabic-translated stimuli in a Qatari sample, showed good diagnostic differentiation and a strong correlation with parent-reported ASD symptoms. Thus, the AI appears to have cross-cultural validity and may be useful as a diagnostic aide to inform clinical judgment and track ASD symptom levels as part of the evaluation process. En ligne : https://doi.org/10.1002/aur.3046 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=518 [article] Development and validation of an Arabic language eye-tracking paradigm for the early screening and diagnosis of autism spectrum disorders in Qatar [texte imprimé] / Iman GHAZAL, Auteur ; I. Richard THOMPSON, Auteur ; Eric W. KLINGEMIER, Auteur ; Mohammed ALDOSARI, Auteur ; Hawraa AL-SHAMMARI, Auteur ; Fatema AL-FARAJ, Auteur ; Saba EL-HAG, Auteur ; Mohamed TOLEFAT, Auteur ; Mogahed ALI, Auteur ; Bisher NASIR, Auteur ; Thomas W. FRAZIER, Auteur . - p.2291-2301. in Autism Research > 16-12 (December 2023) . - p.2291-2301 Index. décimale : PER Périodiques Résumé : Abstract Abnormal eye gaze is a hallmark characteristic of autism spectrum disorder (ASD). The primary aim of the present research was to develop an Arabic version of an objective measure of ASD, the "autism index" (AI), based on eye gaze tracking to social and nonsocial stimuli validated initially in the United States. The initial phase of this study included the translation of English language eye-tracking stimuli into stimuli appropriate for an Arabic-speaking culture. During the second phase, we tested it on a total of 144 children with ASD, and 96 controls. The AI had excellent internal consistency and test-retest reliability. Moreover, the AI showed good differentiation of ASD from control cases (AUC = 0.730, SE = 0.035). The AI was significantly positively correlated with SCQ total raw scores (r = 0.46, p<0.001). ADOS-2 scores were only available in the ASD group and did not show a significant relationship with AI scores (r = 0.10, p = 0.348), likely due to the restricted range. The AI, when implemented using Arabic-translated stimuli in a Qatari sample, showed good diagnostic differentiation and a strong correlation with parent-reported ASD symptoms. Thus, the AI appears to have cross-cultural validity and may be useful as a diagnostic aide to inform clinical judgment and track ASD symptom levels as part of the evaluation process. En ligne : https://doi.org/10.1002/aur.3046 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=518

A Longitudinal Study of Language Trajectories and Treatment Outcomes of Early Intensive Behavioral Intervention for Autism / Thomas W. FRAZIER in Journal of Autism and Developmental Disorders, 51-12 (December 2021)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 51-12 (December 2021) . - p.4534-4550 Titre : A Longitudinal Study of Language Trajectories and Treatment Outcomes of Early Intensive Behavioral Intervention for Autism Type de document : texte imprimé Auteurs : Thomas W. FRAZIER, Auteur ; Eric W. KLINGEMIER, Auteur ; Christa J. ANDERSON, Auteur ; Grace W. GENGOUX, Auteur ; Eric A. YOUNGSTROM, Auteur ; Antonio Y. HARDAN, Auteur Article en page(s) : p.4534-4550 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/therapy  Autistic Disorder  Child  Humans  Language  Longitudinal Studies  Treatment Outcome  Applied behavior analysis  Education  Growth model  Outcomes  Prediction Index. décimale : PER Périodiques Résumé : The present study examined language trajectories and placement outcomes for children with autism spectrum disorder (ASD) receiving early intensive behavioral intervention (EIBI). Language measures were collected at baseline and 6, 12, 18, 24, and 36 months or until exit from EIBI in 131 children with ASD. Growth models estimated overall and subgroup language trajectories. Overall, children receiving EIBI showed substantial increases in language relative to normative expectations. Earlier age at EIBI start, higher baseline cognitive function, and lower baseline ASD severity predicted better language trajectories. Although there was significant variability in language trajectories and educational outcomes, most children showed significant increases in language scores, relative to normative expectations. Additional research, in more representative samples, is needed to understand this variability. En ligne : http://dx.doi.org/10.1007/s10803-021-04900-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=454 [article] A Longitudinal Study of Language Trajectories and Treatment Outcomes of Early Intensive Behavioral Intervention for Autism [texte imprimé] / Thomas W. FRAZIER, Auteur ; Eric W. KLINGEMIER, Auteur ; Christa J. ANDERSON, Auteur ; Grace W. GENGOUX, Auteur ; Eric A. YOUNGSTROM, Auteur ; Antonio Y. HARDAN, Auteur . - p.4534-4550. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 51-12 (December 2021) . - p.4534-4550 Mots-clés : Autism Spectrum Disorder/therapy  Autistic Disorder  Child  Humans  Language  Longitudinal Studies  Treatment Outcome  Applied behavior analysis  Education  Growth model  Outcomes  Prediction Index. décimale : PER Périodiques Résumé : The present study examined language trajectories and placement outcomes for children with autism spectrum disorder (ASD) receiving early intensive behavioral intervention (EIBI). Language measures were collected at baseline and 6, 12, 18, 24, and 36 months or until exit from EIBI in 131 children with ASD. Growth models estimated overall and subgroup language trajectories. Overall, children receiving EIBI showed substantial increases in language relative to normative expectations. Earlier age at EIBI start, higher baseline cognitive function, and lower baseline ASD severity predicted better language trajectories. Although there was significant variability in language trajectories and educational outcomes, most children showed significant increases in language scores, relative to normative expectations. Additional research, in more representative samples, is needed to understand this variability. En ligne : http://dx.doi.org/10.1007/s10803-021-04900-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=454

Social attention as a cross-cultural transdiagnostic neurodevelopmental risk marker / Thomas W. FRAZIER in Autism Research, 14-9 (September 2021)  

Public ISBD [article]  inAutism Research > 14-9 (September 2021) . - p.1873-1885 Titre : Social attention as a cross-cultural transdiagnostic neurodevelopmental risk marker Type de document : texte imprimé Auteurs : Thomas W. FRAZIER, Auteur ; Mirko ULJAREVIĆ, Auteur ; Iman GHAZAL, Auteur ; Eric W. KLINGEMIER, Auteur ; Joshua LANGFUS, Auteur ; Eric A. YOUNGSTROM, Auteur ; Mohammed ALDOSARI, Auteur ; Hawraa AL-SHAMMARI, Auteur ; Saba EL-HAG, Auteur ; Mohamed TOLEFAT, Auteur ; Mogahed ALI, Auteur ; Fouad A. AL-SHABAN, Auteur Article en page(s) : p.1873-1885 Langues : Anglais (eng) Mots-clés : Adolescent  Attention  Autism Spectrum Disorder  Child  Child, Preschool  Cross-Cultural Comparison  Female  Goals  Humans  Infant  Male  Mass Screening  autism  cross-cultural  developmental disability  risk marker  social attention  validation Index. décimale : PER Périodiques Résumé : The primary objectives of this study were to evaluate the structure and age-related stability of social attention in English and Arabic-speaking youth and to compare social attention between children with autism spectrum disorder (ASD), other developmental disabilities (DD), and typically-developing controls. Eye-tracking data were collected from US (N = 270) and Qatari (N = 242) youth ages 1-17, including children evaluated for possible ASD. Participants viewed 44 stimuli from seven social paradigms. Fixation was computed for areas of interest within each stimulus. Latent variable models examined the structure of social attention. Generalized estimating equation models examined the effect of age, sex, culture, and diagnostic group on social attention. The best-fitting model included a general social attention factor and six specific factors. Cultural differences in social attention were minimal and social attention was stable across age (r = 0.03), but females showed significantly greater social attention than males (d = 0.28). Social attention was weaker in DD (d = -0.17) and lowest in ASD (d = -0.38) relative to controls. Differences were of sufficient magnitude across areas-of-interest to reliably differentiate DD from controls (AUC = 0.80) and ASD-only from all other cases (AUC = 0.76). A social attention dimension that represents an early-life preference for socially salient information was identified. This preference was cross-culturally consistent and stable across development but stronger in females and weaker in DD, especially ASD. Given rapid and easy-to-collect remote eye tracking administration, social attention measurement may be useful for developmental monitoring. Acquisition of population norms, analogous to height/weight/head circumference, might enhance early screening and tracking of neurodevelopment. LAY SUMMARY: This research found that social attention is a single dimension of behavior that represents a strong preference for social stimuli, is consistent across cultures, stable across age, and stronger in females. Children with developmental disabilities had lower levels of social attention than neurotypical children and children with autism spectrum disorder had the lowest levels of social attention. En ligne : http://dx.doi.org/10.1002/aur.2532 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=449 [article] Social attention as a cross-cultural transdiagnostic neurodevelopmental risk marker [texte imprimé] / Thomas W. FRAZIER, Auteur ; Mirko ULJAREVIĆ, Auteur ; Iman GHAZAL, Auteur ; Eric W. KLINGEMIER, Auteur ; Joshua LANGFUS, Auteur ; Eric A. YOUNGSTROM, Auteur ; Mohammed ALDOSARI, Auteur ; Hawraa AL-SHAMMARI, Auteur ; Saba EL-HAG, Auteur ; Mohamed TOLEFAT, Auteur ; Mogahed ALI, Auteur ; Fouad A. AL-SHABAN, Auteur . - p.1873-1885. Langues : Anglais (eng) in Autism Research > 14-9 (September 2021) . - p.1873-1885 Mots-clés : Adolescent  Attention  Autism Spectrum Disorder  Child  Child, Preschool  Cross-Cultural Comparison  Female  Goals  Humans  Infant  Male  Mass Screening  autism  cross-cultural  developmental disability  risk marker  social attention  validation Index. décimale : PER Périodiques Résumé : The primary objectives of this study were to evaluate the structure and age-related stability of social attention in English and Arabic-speaking youth and to compare social attention between children with autism spectrum disorder (ASD), other developmental disabilities (DD), and typically-developing controls. Eye-tracking data were collected from US (N = 270) and Qatari (N = 242) youth ages 1-17, including children evaluated for possible ASD. Participants viewed 44 stimuli from seven social paradigms. Fixation was computed for areas of interest within each stimulus. Latent variable models examined the structure of social attention. Generalized estimating equation models examined the effect of age, sex, culture, and diagnostic group on social attention. The best-fitting model included a general social attention factor and six specific factors. Cultural differences in social attention were minimal and social attention was stable across age (r = 0.03), but females showed significantly greater social attention than males (d = 0.28). Social attention was weaker in DD (d = -0.17) and lowest in ASD (d = -0.38) relative to controls. Differences were of sufficient magnitude across areas-of-interest to reliably differentiate DD from controls (AUC = 0.80) and ASD-only from all other cases (AUC = 0.76). A social attention dimension that represents an early-life preference for socially salient information was identified. This preference was cross-culturally consistent and stable across development but stronger in females and weaker in DD, especially ASD. Given rapid and easy-to-collect remote eye tracking administration, social attention measurement may be useful for developmental monitoring. Acquisition of population norms, analogous to height/weight/head circumference, might enhance early screening and tracking of neurodevelopment. LAY SUMMARY: This research found that social attention is a single dimension of behavior that represents a strong preference for social stimuli, is consistent across cultures, stable across age, and stronger in females. Children with developmental disabilities had lower levels of social attention than neurotypical children and children with autism spectrum disorder had the lowest levels of social attention. En ligne : http://dx.doi.org/10.1002/aur.2532 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=449

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