Beyond orchids and dandelions: Susceptibility to environmental influences is not bimodal / Xiaoya ZHANG in Development and Psychopathology, 35-1 (February 2023)  

Public ISBD [article]  inDevelopment and Psychopathology > 35-1 (February 2023) . - p.191-203 Titre : Beyond orchids and dandelions: Susceptibility to environmental influences is not bimodal Type de document : Texte imprimé et/ou numérique Auteurs : Xiaoya ZHANG, Auteur ; Keith WIDAMAN, Auteur ; Jay BELSKY, Auteur Article en page(s) : p.191-203 Langues : Anglais (eng) Mots-clés : differential susceptibility  domain general versus specific  polygenic scores  susceptibility continuum  temperament Index. décimale : PER Périodiques Résumé : This study focused on generality versus specificity of susceptibility of effects of eight family and child-care exposures measured between 3 and 54 months of age (e.g., sensitive parenting, child-care quality) on five child development outcomes assessed at age 4.5 years (e.g. behavior problems, preacademic skill), using data from The National Institute of Child Health and Human Development (NICHD) Study of Early Child Care and Youth Development (n = 1,364, boys = 705; White = 1,097, Black = 176, other = 91), while applying a novel influence-statistics method. Results indicated that susceptibility across the environment-predictor:child-outcome associations is normally rather than bimodally (i.e., orchid-dandelion) distributed. Analysis of susceptibility documents both domain generality and specificity of developmental plasticity, with effect sizes proving small in the former case. As predicted, children who as infants had difficult temperaments or who scored higher on a polygenic-plasticity score (serotonin-transporter-linked promoter region [5-HTTLPR], dopamine receptor D4 [DRD4], brain-derived neurotrophic factor [BDNF]) proved somewhat more susceptible to some of the environmental effects investigated. Results lead to the recommendation that two-types-of-individuals vis-a-vis susceptibility to environmental influences be questioned and general-trait conceptions of susceptibility be further investigated. En ligne : https://doi.org/10.1017/S0954579421000821 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=499 [article] Beyond orchids and dandelions: Susceptibility to environmental influences is not bimodal [Texte imprimé et/ou numérique] / Xiaoya ZHANG, Auteur ; Keith WIDAMAN, Auteur ; Jay BELSKY, Auteur . - p.191-203. Langues : Anglais (eng) in Development and Psychopathology > 35-1 (February 2023) . - p.191-203 Mots-clés : differential susceptibility  domain general versus specific  polygenic scores  susceptibility continuum  temperament Index. décimale : PER Périodiques Résumé : This study focused on generality versus specificity of susceptibility of effects of eight family and child-care exposures measured between 3 and 54 months of age (e.g., sensitive parenting, child-care quality) on five child development outcomes assessed at age 4.5 years (e.g. behavior problems, preacademic skill), using data from The National Institute of Child Health and Human Development (NICHD) Study of Early Child Care and Youth Development (n = 1,364, boys = 705; White = 1,097, Black = 176, other = 91), while applying a novel influence-statistics method. Results indicated that susceptibility across the environment-predictor:child-outcome associations is normally rather than bimodally (i.e., orchid-dandelion) distributed. Analysis of susceptibility documents both domain generality and specificity of developmental plasticity, with effect sizes proving small in the former case. As predicted, children who as infants had difficult temperaments or who scored higher on a polygenic-plasticity score (serotonin-transporter-linked promoter region [5-HTTLPR], dopamine receptor D4 [DRD4], brain-derived neurotrophic factor [BDNF]) proved somewhat more susceptible to some of the environmental effects investigated. Results lead to the recommendation that two-types-of-individuals vis-a-vis susceptibility to environmental influences be questioned and general-trait conceptions of susceptibility be further investigated. En ligne : https://doi.org/10.1017/S0954579421000821 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=499

Differential susceptibility 2.0: Are the same children affected by different experiences and exposures? / Jay BELSKY in Development and Psychopathology, 34-3 (August 2022)  

Public ISBD [article]  inDevelopment and Psychopathology > 34-3 (August 2022) . - p.1025-1033 Titre : Differential susceptibility 2.0: Are the same children affected by different experiences and exposures? Type de document : Texte imprimé et/ou numérique Auteurs : Jay BELSKY, Auteur ; Xiaoya ZHANG, Auteur ; Kristina SAYLER, Auteur Article en page(s) : p.1025-1033 Langues : Anglais (eng) Mots-clés : differential susceptibility  childcare  domain specific  domain general  polygenic Index. décimale : PER Périodiques Résumé : Differential susceptibility theory stipulates that some children are more susceptible than others to both supportive and adverse developmental experiences/exposures. What remains unclear is whether the same individuals are most affected by different exposures (i.e., domain general vs. specific). We address this issue empirically for the first time using, for illustrative and proof-of-principle purposes, a novel influence-statistics’ method with data from the National Institute of Child Health and Human Development (NICHD) Study of Early Child Care. Results indicated that previously documented effects of greater quality of care on enhanced pre-academic skills and greater quantity of care on more behavior problems apply mostly to different children. Analyses validating the new method indicated, as predicted, that (a) the quantity-of-care effect applied principally to children from more socioeconomically advantaged families and that (b) being highly susceptible to both, one or neither childcare effect varied as a function of a three-gene, polygenic-plasticity score (serotonin transporter linked polymorphic region [5-HTTLPR], dopamine receptor D4 [DRD4], brain-derived neurotrophic factor [BDNF]) in a dose “response manner (i.e., 2>1>0). While domain-specific findings involving child-care effects cannot be generalized to other environmental influences, the influence-statistics’ approach appears well suited for investigating the generality “specificity of environment effects, that is, of œdifferential, differential susceptibility. � En ligne : http://dx.doi.org/10.1017/S0954579420002205 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=485 [article] Differential susceptibility 2.0: Are the same children affected by different experiences and exposures? [Texte imprimé et/ou numérique] / Jay BELSKY, Auteur ; Xiaoya ZHANG, Auteur ; Kristina SAYLER, Auteur . - p.1025-1033. Langues : Anglais (eng) in Development and Psychopathology > 34-3 (August 2022) . - p.1025-1033 Mots-clés : differential susceptibility  childcare  domain specific  domain general  polygenic Index. décimale : PER Périodiques Résumé : Differential susceptibility theory stipulates that some children are more susceptible than others to both supportive and adverse developmental experiences/exposures. What remains unclear is whether the same individuals are most affected by different exposures (i.e., domain general vs. specific). We address this issue empirically for the first time using, for illustrative and proof-of-principle purposes, a novel influence-statistics’ method with data from the National Institute of Child Health and Human Development (NICHD) Study of Early Child Care. Results indicated that previously documented effects of greater quality of care on enhanced pre-academic skills and greater quantity of care on more behavior problems apply mostly to different children. Analyses validating the new method indicated, as predicted, that (a) the quantity-of-care effect applied principally to children from more socioeconomically advantaged families and that (b) being highly susceptible to both, one or neither childcare effect varied as a function of a three-gene, polygenic-plasticity score (serotonin transporter linked polymorphic region [5-HTTLPR], dopamine receptor D4 [DRD4], brain-derived neurotrophic factor [BDNF]) in a dose “response manner (i.e., 2>1>0). While domain-specific findings involving child-care effects cannot be generalized to other environmental influences, the influence-statistics’ approach appears well suited for investigating the generality “specificity of environment effects, that is, of œdifferential, differential susceptibility. � En ligne : http://dx.doi.org/10.1017/S0954579420002205 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=485

Environmental harshness and unpredictability: Do they affect the same parents and children? / Xiaoya ZHANG in Development and Psychopathology, 34-2 (May 2022)  

Public ISBD [article]  inDevelopment and Psychopathology > 34-2 (May 2022) . - 667-673 Titre : Environmental harshness and unpredictability: Do they affect the same parents and children? Type de document : Texte imprimé et/ou numérique Auteurs : Xiaoya ZHANG, Auteur ; Gabriel L. SCHLOMER, Auteur ; Bruce J. ELLIS, Auteur ; Jay BELSKY, Auteur Article en page(s) : 667-673 Langues : Anglais (eng) Mots-clés : differential susceptibility  harshness  life-history theory  unpredictability Index. décimale : PER Périodiques Résumé : Differential susceptibility theory stipulates that individuals vary in their susceptibility to environmental effects, often implying that the same individuals differ in the same way in their susceptibility to different environmental exposures. The latter point is addressed herein by evaluating the extent to which early-life harshness and unpredictability affect mother's psychological well-being and parenting, as well as their adolescent's life-history strategy, as reflected in number of sexual partners by age 15 years, drawing on data from the National Institute of Child Health and Human Development (NICHD) Study of Early Child Care and Youth Development. Results indicated that mothers whose well-being and parenting proved more susceptible to harshness also proved somewhat more susceptible to environmental unpredictability, with the same being true of adolescent sexual behavior. Nevertheless, findings caution against overgeneralizing sample-level findings to all individuals. En ligne : http://dx.doi.org/10.1017/s095457942100095x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474 [article] Environmental harshness and unpredictability: Do they affect the same parents and children? [Texte imprimé et/ou numérique] / Xiaoya ZHANG, Auteur ; Gabriel L. SCHLOMER, Auteur ; Bruce J. ELLIS, Auteur ; Jay BELSKY, Auteur . - 667-673. Langues : Anglais (eng) in Development and Psychopathology > 34-2 (May 2022) . - 667-673 Mots-clés : differential susceptibility  harshness  life-history theory  unpredictability Index. décimale : PER Périodiques Résumé : Differential susceptibility theory stipulates that individuals vary in their susceptibility to environmental effects, often implying that the same individuals differ in the same way in their susceptibility to different environmental exposures. The latter point is addressed herein by evaluating the extent to which early-life harshness and unpredictability affect mother's psychological well-being and parenting, as well as their adolescent's life-history strategy, as reflected in number of sexual partners by age 15 years, drawing on data from the National Institute of Child Health and Human Development (NICHD) Study of Early Child Care and Youth Development. Results indicated that mothers whose well-being and parenting proved more susceptible to harshness also proved somewhat more susceptible to environmental unpredictability, with the same being true of adolescent sexual behavior. Nevertheless, findings caution against overgeneralizing sample-level findings to all individuals. En ligne : http://dx.doi.org/10.1017/s095457942100095x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474

Infant temperament, early-childhood parenting, and early-adolescent development: Testing alternative models of Parenting x Temperament interaction / Xiaoya ZHANG in Development and Psychopathology, 34-3 (August 2022)  

Public ISBD [article]  inDevelopment and Psychopathology > 34-3 (August 2022) . - p.784-795 Titre : Infant temperament, early-childhood parenting, and early-adolescent development: Testing alternative models of Parenting x Temperament interaction Type de document : Texte imprimé et/ou numérique Auteurs : Xiaoya ZHANG, Auteur ; Kristina SAYLER, Auteur ; Sarah HARTMAN, Auteur ; Jay BELSKY, Auteur Année de publication : 2022 Article en page(s) : p.784-795 Langues : Anglais (eng) Mots-clés : temperament-X-parenting interaction  differential-susceptibility  diathesis-stress  re-parameterized model comparison  ALSPAC Index. décimale : PER Périodiques Résumé : Here we evaluate whether infant difficult temperament (6 months) functions as a vulnerability or more general plasticity factor when investigating effects of early-childhood parenting (8 “42 months) on both positive and negative early-adolescent socioemotional development (age 8 “11 years). Using data from the Avon Longitudinal Study of Parents and Children (ALSPAC, N = 14,541) and a re-parameterized model-testing approach to distinguish alternative person × environment conceptual models, results indicated that temperament × parenting interacted in predicting externalizing (i.e., hyperactivity, conduct problems), but not other behavior (i.e., emotional symptoms, peer problems), in a (weak) differential susceptibility manner. While more and less supportive parenting predicted, respectively, fewer and more behavior problems, it did so more strongly for children who were more difficult as infants. En ligne : http://dx.doi.org/10.1017/S0954579420002096 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=484 [article] Infant temperament, early-childhood parenting, and early-adolescent development: Testing alternative models of Parenting x Temperament interaction [Texte imprimé et/ou numérique] / Xiaoya ZHANG, Auteur ; Kristina SAYLER, Auteur ; Sarah HARTMAN, Auteur ; Jay BELSKY, Auteur . - 2022 . - p.784-795. Langues : Anglais (eng) in Development and Psychopathology > 34-3 (August 2022) . - p.784-795 Mots-clés : temperament-X-parenting interaction  differential-susceptibility  diathesis-stress  re-parameterized model comparison  ALSPAC Index. décimale : PER Périodiques Résumé : Here we evaluate whether infant difficult temperament (6 months) functions as a vulnerability or more general plasticity factor when investigating effects of early-childhood parenting (8 “42 months) on both positive and negative early-adolescent socioemotional development (age 8 “11 years). Using data from the Avon Longitudinal Study of Parents and Children (ALSPAC, N = 14,541) and a re-parameterized model-testing approach to distinguish alternative person × environment conceptual models, results indicated that temperament × parenting interacted in predicting externalizing (i.e., hyperactivity, conduct problems), but not other behavior (i.e., emotional symptoms, peer problems), in a (weak) differential susceptibility manner. While more and less supportive parenting predicted, respectively, fewer and more behavior problems, it did so more strongly for children who were more difficult as infants. En ligne : http://dx.doi.org/10.1017/S0954579420002096 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=484

Three phases of Gene * Environment interaction research: Theoretical assumptions underlying gene selection / Xiaoya ZHANG in Development and Psychopathology, 34-1 (February 2022)  

Public ISBD [article]  inDevelopment and Psychopathology > 34-1 (February 2022) . - p.295-306 Titre : Three phases of Gene * Environment interaction research: Theoretical assumptions underlying gene selection Type de document : Texte imprimé et/ou numérique Auteurs : Xiaoya ZHANG, Auteur ; Jay BELSKY, Auteur Article en page(s) : p.295-306 Langues : Anglais (eng) Mots-clés : diathesis stress  differential susceptibility  G*E interaction  gene selection Index. décimale : PER Périodiques Résumé : Some Gene * Environment interaction (G*E) research has focused upon single candidate genes, whereas other related work has targeted multiple genes (e.g., polygenic scores). Each approach has informed efforts to identify individuals who are either especially vulnerable to the negative effects of contextual adversity (diathesis stress) or especially susceptible to both positive and negative contextual conditions (differential susceptibility). A critical step in all such molecular G*E research is the selection of genetic variants thought to moderate environmental influences, a subject that has not received a great deal of attention in critiques of G*E research (beyond the observation of small effects of individual genes). Here we conceptually distinguish three phases of G*E work based on the selection of genes presumed to moderate environmental effects and the theoretical basis of such decisions: (a) single candidate genes, (b) composited (multiple) candidate genes, and (c) GWAS-derived polygenic scores. This illustrative, not exhaustive, review makes it clear that implicit or explicit theoretical assumptions inform gene selection in ways that have not been clearly articulated or fully appreciated. En ligne : http://dx.doi.org/10.1017/s0954579420000966 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474 [article] Three phases of Gene * Environment interaction research: Theoretical assumptions underlying gene selection [Texte imprimé et/ou numérique] / Xiaoya ZHANG, Auteur ; Jay BELSKY, Auteur . - p.295-306. Langues : Anglais (eng) in Development and Psychopathology > 34-1 (February 2022) . - p.295-306 Mots-clés : diathesis stress  differential susceptibility  G*E interaction  gene selection Index. décimale : PER Périodiques Résumé : Some Gene * Environment interaction (G*E) research has focused upon single candidate genes, whereas other related work has targeted multiple genes (e.g., polygenic scores). Each approach has informed efforts to identify individuals who are either especially vulnerable to the negative effects of contextual adversity (diathesis stress) or especially susceptible to both positive and negative contextual conditions (differential susceptibility). A critical step in all such molecular G*E research is the selection of genetic variants thought to moderate environmental influences, a subject that has not received a great deal of attention in critiques of G*E research (beyond the observation of small effects of individual genes). Here we conceptually distinguish three phases of G*E work based on the selection of genes presumed to moderate environmental effects and the theoretical basis of such decisions: (a) single candidate genes, (b) composited (multiple) candidate genes, and (c) GWAS-derived polygenic scores. This illustrative, not exhaustive, review makes it clear that implicit or explicit theoretical assumptions inform gene selection in ways that have not been clearly articulated or fully appreciated. En ligne : http://dx.doi.org/10.1017/s0954579420000966 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474

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