Behavioral and cardiac responses to emotional stroop in adults with autism spectrum disorders: influence of medication / Karen J. MATHEWSON in Autism Research, 4-2 (April 2011)  

Public ISBD [article]  inAutism Research > 4-2 (April 2011) . - p.98-108 Titre : Behavioral and cardiac responses to emotional stroop in adults with autism spectrum disorders: influence of medication Type de document : texte imprimé Auteurs : Karen J. MATHEWSON, Auteur ; Irene E. DRMIC, Auteur ; Michelle K. JETHA, Auteur ; Susan E. BRYSON, Auteur ; Joel O. GOLDBERG, Auteur ; Geoffrey B. C. HALL, Auteur ; Diane L. SANTESSO, Auteur ; Sidney SEGALOWITZ, Auteur ; Louis A. SCHMIDT, Auteur Année de publication : 2011 Article en page(s) : p.98-108 Langues : Anglais (eng) Mots-clés : autism spectrum disorders (ASD)  heart period  respiratory sinus arrhythmia (RSA)  Stroop task Index. décimale : PER Périodiques Résumé : Researchers have recently hypothesized that autism spectrum disorders (ASD) may be partly characterized by physiological over-arousal. One way to assess physiological arousal is through autonomic measures. Here heart period (HP) and parasympathetic activity measured by respiratory sinus arrhythmia (RSA) were examined in adults with ASD and matched controls at rest and during performance of an emotional Stroop task. Resting HP and RSA were lower in adults with ASD than in matched controls, consistent with hypothesized over-arousal in ASD. However, dividing the ASD group on the basis of antipsychotic medication usage revealed that group differences in autonomic arousal may be related to the effects of these medications or their correlates. Autonomic adjustments for Stroop performance were comparable across groups, but in the control group, larger RSA reductions were correlated with faster responding (i.e., better performance). This relation was reversed in the unmedicated ASD group and absent in the medicated ASD group. Findings highlight the importance of considering medication status in the recently burgeoning area of psychophysiological studies of autism. En ligne : http://dx.doi.org/10.1002/aur.176 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=121 [article] Behavioral and cardiac responses to emotional stroop in adults with autism spectrum disorders: influence of medication [texte imprimé] / Karen J. MATHEWSON, Auteur ; Irene E. DRMIC, Auteur ; Michelle K. JETHA, Auteur ; Susan E. BRYSON, Auteur ; Joel O. GOLDBERG, Auteur ; Geoffrey B. C. HALL, Auteur ; Diane L. SANTESSO, Auteur ; Sidney SEGALOWITZ, Auteur ; Louis A. SCHMIDT, Auteur . - 2011 . - p.98-108. Langues : Anglais (eng) in Autism Research > 4-2 (April 2011) . - p.98-108 Mots-clés : autism spectrum disorders (ASD)  heart period  respiratory sinus arrhythmia (RSA)  Stroop task Index. décimale : PER Périodiques Résumé : Researchers have recently hypothesized that autism spectrum disorders (ASD) may be partly characterized by physiological over-arousal. One way to assess physiological arousal is through autonomic measures. Here heart period (HP) and parasympathetic activity measured by respiratory sinus arrhythmia (RSA) were examined in adults with ASD and matched controls at rest and during performance of an emotional Stroop task. Resting HP and RSA were lower in adults with ASD than in matched controls, consistent with hypothesized over-arousal in ASD. However, dividing the ASD group on the basis of antipsychotic medication usage revealed that group differences in autonomic arousal may be related to the effects of these medications or their correlates. Autonomic adjustments for Stroop performance were comparable across groups, but in the control group, larger RSA reductions were correlated with faster responding (i.e., better performance). This relation was reversed in the unmedicated ASD group and absent in the medicated ASD group. Findings highlight the importance of considering medication status in the recently burgeoning area of psychophysiological studies of autism. En ligne : http://dx.doi.org/10.1002/aur.176 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=121

Emerging cognitive profiles in high-risk infants with and without autism spectrum disorder / Jessica BRIAN in Research in Autism Spectrum Disorders, 8-11 (November 2014)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 8-11 (November 2014) . - p.1557-1566 Titre : Emerging cognitive profiles in high-risk infants with and without autism spectrum disorder Type de document : texte imprimé Auteurs : Jessica BRIAN, Auteur ; C. RONCADIN, Auteur ; E. DUKU, Auteur ; Susan E. BRYSON, Auteur ; I. M. SMITH, Auteur ; W. ROBERTS, Auteur ; P. SZATMARI, Auteur ; Irene E. DRMIC, Auteur ; Lonnie ZWAIGENBAUM, Auteur Article en page(s) : p.1557-1566 Langues : Anglais (eng) Mots-clés : High-risk siblings  Cognitive development  Infants  Toddlers  Developmental trajectories  ASD Index. décimale : PER Périodiques Résumé : This paper examined early developmental trajectories in a large, longitudinal sample at high-risk for ASD (‘HR’) and low-risk (‘LR’) controls, and the association of trajectories with 3-year diagnosis. Developmental assessments were conducted at 6, 12, 24 months, and 3 years, with blinded “clinical best-estimate” expert diagnosis at age 3. HR infants were enrolled based only on familial risk. LR infants, from community sources, had no first- or second-degree ASD relatives. All infants were born at 36–42 weeks, weighing ≥2500 g, with no identifiable neurological, genetic, or severe sensory/motor disorders. Analytic phase I: semi-parametric group-based modeling to identify distinct developmental trajectories (n = 680; 487 HR; 193 LR); phase II: Trajectory membership in relation to 3-year diagnosis (n = 424; 310 HR; 114 LR). Three distinct trajectories emerged (1) inclining; (2) stable-average; (3) declining; trajectory membership predicted diagnosis (χ2 = 99.40; p lt; .001). Most ASD cases were in stable-average (50.6%) or declining trajectories (33.8%); most non-ASD-HR infants were in inclining (51.9%) or stable-average (40.3%) trajectories. The majority of LR controls were in the inclining trajectory (78.9%). Within the declining trajectory, over half had ASD (57.8%), but 40% were non-ASD-HR infants. Declining/plateauing raw scores were associated with, but not exclusive to, ASD. Findings underscore the importance of monitoring the emergence of ASD symptoms and overall development in high-risk children. Evidence of developmental slowing or decline may be associated not only with ASD, but with other suboptimal outcomes, warranting careful clinical follow-up. En ligne : http://dx.doi.org/10.1016/j.rasd.2014.07.021 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=241 [article] Emerging cognitive profiles in high-risk infants with and without autism spectrum disorder [texte imprimé] / Jessica BRIAN, Auteur ; C. RONCADIN, Auteur ; E. DUKU, Auteur ; Susan E. BRYSON, Auteur ; I. M. SMITH, Auteur ; W. ROBERTS, Auteur ; P. SZATMARI, Auteur ; Irene E. DRMIC, Auteur ; Lonnie ZWAIGENBAUM, Auteur . - p.1557-1566. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 8-11 (November 2014) . - p.1557-1566 Mots-clés : High-risk siblings  Cognitive development  Infants  Toddlers  Developmental trajectories  ASD Index. décimale : PER Périodiques Résumé : This paper examined early developmental trajectories in a large, longitudinal sample at high-risk for ASD (‘HR’) and low-risk (‘LR’) controls, and the association of trajectories with 3-year diagnosis. Developmental assessments were conducted at 6, 12, 24 months, and 3 years, with blinded “clinical best-estimate” expert diagnosis at age 3. HR infants were enrolled based only on familial risk. LR infants, from community sources, had no first- or second-degree ASD relatives. All infants were born at 36–42 weeks, weighing ≥2500 g, with no identifiable neurological, genetic, or severe sensory/motor disorders. Analytic phase I: semi-parametric group-based modeling to identify distinct developmental trajectories (n = 680; 487 HR; 193 LR); phase II: Trajectory membership in relation to 3-year diagnosis (n = 424; 310 HR; 114 LR). Three distinct trajectories emerged (1) inclining; (2) stable-average; (3) declining; trajectory membership predicted diagnosis (χ2 = 99.40; p lt; .001). Most ASD cases were in stable-average (50.6%) or declining trajectories (33.8%); most non-ASD-HR infants were in inclining (51.9%) or stable-average (40.3%) trajectories. The majority of LR controls were in the inclining trajectory (78.9%). Within the declining trajectory, over half had ASD (57.8%), but 40% were non-ASD-HR infants. Declining/plateauing raw scores were associated with, but not exclusive to, ASD. Findings underscore the importance of monitoring the emergence of ASD symptoms and overall development in high-risk children. Evidence of developmental slowing or decline may be associated not only with ASD, but with other suboptimal outcomes, warranting careful clinical follow-up. En ligne : http://dx.doi.org/10.1016/j.rasd.2014.07.021 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=241

Feasibility, Acceptability and Preliminary Treatment Outcomes in a School-Based CBT Intervention Program for Adolescents with ASD and Anxiety in Singapore / Irene E. DRMIC in Journal of Autism and Developmental Disorders, 47-12 (December 2017)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 47-12 (December 2017) . - p.3909-3929 Titre : Feasibility, Acceptability and Preliminary Treatment Outcomes in a School-Based CBT Intervention Program for Adolescents with ASD and Anxiety in Singapore Type de document : texte imprimé Auteurs : Irene E. DRMIC, Auteur ; Mariam ALJUNIED, Auteur ; J. REAVEN, Auteur Année de publication : 2017 Article en page(s) : p.3909-3929 Langues : Anglais (eng) Mots-clés : Adolescents  Anxiety  Autism spectrum disorder (ASD)  Cognitive behavior therapy (CBT)  Facing your fears  Schools Index. décimale : PER Périodiques Résumé : Adolescents with autism spectrum disorder (ASD) are at high risk for anxiety difficulties and disorders. Clinic-based cognitive behavioral therapy (CBT) is effective; however, few published school-based CBT programs for youth with ASD exist. In this study, the Facing Your Fears CBT protocol was adapted for delivery and piloted within a school setting by non-clinicians, with culturally appropriate adaptations. 44 13-15 aged youth with ASD from 22 mainstream schools in Singapore participated. Feasibility, acceptability and preliminary treatment outcomes were examined. Decreases in youth and parent reported anxiety symptoms were reported. Staff and parents found the program useful. Stakeholder support was important for implementation. Initial findings reflect the importance of carefully bridging research-to-practice for youth with ASD and anxiety. En ligne : http://dx.doi.org/10.1007/s10803-016-3007-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=326 [article] Feasibility, Acceptability and Preliminary Treatment Outcomes in a School-Based CBT Intervention Program for Adolescents with ASD and Anxiety in Singapore [texte imprimé] / Irene E. DRMIC, Auteur ; Mariam ALJUNIED, Auteur ; J. REAVEN, Auteur . - 2017 . - p.3909-3929. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 47-12 (December 2017) . - p.3909-3929 Mots-clés : Adolescents  Anxiety  Autism spectrum disorder (ASD)  Cognitive behavior therapy (CBT)  Facing your fears  Schools Index. décimale : PER Périodiques Résumé : Adolescents with autism spectrum disorder (ASD) are at high risk for anxiety difficulties and disorders. Clinic-based cognitive behavioral therapy (CBT) is effective; however, few published school-based CBT programs for youth with ASD exist. In this study, the Facing Your Fears CBT protocol was adapted for delivery and piloted within a school setting by non-clinicians, with culturally appropriate adaptations. 44 13-15 aged youth with ASD from 22 mainstream schools in Singapore participated. Feasibility, acceptability and preliminary treatment outcomes were examined. Decreases in youth and parent reported anxiety symptoms were reported. Staff and parents found the program useful. Stakeholder support was important for implementation. Initial findings reflect the importance of carefully bridging research-to-practice for youth with ASD and anxiety. En ligne : http://dx.doi.org/10.1007/s10803-016-3007-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=326

Parents’ Perspectives on Participating in Genetic Research in Autism / Magan TROTTIER in Journal of Autism and Developmental Disorders, 43-3 (March 2013)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 43-3 (March 2013) . - p.556-568 Titre : Parents’ Perspectives on Participating in Genetic Research in Autism Type de document : texte imprimé Auteurs : Magan TROTTIER, Auteur ; Wendy ROBERTS, Auteur ; Irene E. DRMIC, Auteur ; Stephen SCHERER, Auteur ; Rosanna WEKSBERG, Auteur ; Cheryl CYTRYNBAUM, Auteur ; David CHITAYAT, Auteur ; Cheryl SHUMAN, Auteur ; Fiona A. MILLER, Auteur Article en page(s) : p.556-568 Langues : Anglais (eng) Mots-clés : Autism  Parent experiences  Genetic research  Motivations  Expectations  Genetic result Index. décimale : PER Périodiques Résumé : Genetic research in autism depends on the willingness of individuals with autism to participate; thus, there is a duty to assess participants’ needs in the research process. We report on families’ motives and expectations related to their participation in autism genetic research. Respondents valued having a genetic result, as it alleviates guilt, promotes awareness, and may be used to tailor interventions and for family planning. The act of participating was distinctly significant, as it provided personal control, a connection to autism experts, networking with families, and hope for the future. The results of this study highlight complex factors involved in families’ decisions to participate in autism genetic research and provide points to consider for this population of research participants. En ligne : http://dx.doi.org/10.1007/s10803-012-1592-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=192 [article] Parents’ Perspectives on Participating in Genetic Research in Autism [texte imprimé] / Magan TROTTIER, Auteur ; Wendy ROBERTS, Auteur ; Irene E. DRMIC, Auteur ; Stephen SCHERER, Auteur ; Rosanna WEKSBERG, Auteur ; Cheryl CYTRYNBAUM, Auteur ; David CHITAYAT, Auteur ; Cheryl SHUMAN, Auteur ; Fiona A. MILLER, Auteur . - p.556-568. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 43-3 (March 2013) . - p.556-568 Mots-clés : Autism  Parent experiences  Genetic research  Motivations  Expectations  Genetic result Index. décimale : PER Périodiques Résumé : Genetic research in autism depends on the willingness of individuals with autism to participate; thus, there is a duty to assess participants’ needs in the research process. We report on families’ motives and expectations related to their participation in autism genetic research. Respondents valued having a genetic result, as it alleviates guilt, promotes awareness, and may be used to tailor interventions and for family planning. The act of participating was distinctly significant, as it provided personal control, a connection to autism experts, networking with families, and hope for the future. The results of this study highlight complex factors involved in families’ decisions to participate in autism genetic research and provide points to consider for this population of research participants. En ligne : http://dx.doi.org/10.1007/s10803-012-1592-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=192

The Association Between Autism Symptomatology and Adaptive Functioning Over Six Months: Findings from the Pilot Phase of the PARC Study / Tamar David COHEN in Journal of Autism and Developmental Disorders, 55-10 (October 2025)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 55-10 (October 2025) . - p.3582-3589 Titre : The Association Between Autism Symptomatology and Adaptive Functioning Over Six Months: Findings from the Pilot Phase of the PARC Study Type de document : texte imprimé Auteurs : Tamar David COHEN, Auteur ; Judah KOLLER, Auteur ; Eric DUKU, Auteur ; Anna KATA, Auteur ; Colleen ANDERSON, Auteur ; Teresa BENNETT, Auteur ; Amber CAUWENBERGS, Auteur ; Kathleen DEKKER, Auteur ; Briano DIREZZE, Auteur ; Irene E. DRMIC, Auteur ; Judy EERKES, Auteur ; Stephen J. GENTLES, Auteur ; Kathy GEORGIADES, Auteur ; Lorraine HOULT, Auteur ; Olaf Kraus DE CAMARGO, Auteur ; Bill MAHONEY, Auteur ; Ronit MESTERMAN, Auteur ; Olivia NG, Auteur ; Sue ROBERTSON, Auteur ; Caroline RONCADIN, Auteur ; Stelios GEORGIADES, Auteur Article en page(s) : p.3582-3589 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : In the context of developmental trajectories, the association between adaptive functioning and core autism symptomatology remains unclear. The current study examines the associations of adaptive behavior with autism symptom sub-domains and with different facets of symptom expression. En ligne : https://doi.org/10.1007/s10803-024-06460-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568 [article] The Association Between Autism Symptomatology and Adaptive Functioning Over Six Months: Findings from the Pilot Phase of the PARC Study [texte imprimé] / Tamar David COHEN, Auteur ; Judah KOLLER, Auteur ; Eric DUKU, Auteur ; Anna KATA, Auteur ; Colleen ANDERSON, Auteur ; Teresa BENNETT, Auteur ; Amber CAUWENBERGS, Auteur ; Kathleen DEKKER, Auteur ; Briano DIREZZE, Auteur ; Irene E. DRMIC, Auteur ; Judy EERKES, Auteur ; Stephen J. GENTLES, Auteur ; Kathy GEORGIADES, Auteur ; Lorraine HOULT, Auteur ; Olaf Kraus DE CAMARGO, Auteur ; Bill MAHONEY, Auteur ; Ronit MESTERMAN, Auteur ; Olivia NG, Auteur ; Sue ROBERTSON, Auteur ; Caroline RONCADIN, Auteur ; Stelios GEORGIADES, Auteur . - p.3582-3589. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 55-10 (October 2025) . - p.3582-3589 Index. décimale : PER Périodiques Résumé : In the context of developmental trajectories, the association between adaptive functioning and core autism symptomatology remains unclear. The current study examines the associations of adaptive behavior with autism symptom sub-domains and with different facets of symptom expression. En ligne : https://doi.org/10.1007/s10803-024-06460-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568

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