Anxiety Disorders in Adults with Autism Spectrum Disorder: A Population-Based Study / Victoria NIMMO-SMITH in Journal of Autism and Developmental Disorders, 50-1 (January 2020)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 50-1 (January 2020) . - p.308-318 Titre : Anxiety Disorders in Adults with Autism Spectrum Disorder: A Population-Based Study Type de document : Texte imprimé et/ou numérique Auteurs : Victoria NIMMO-SMITH, Auteur ; Hein HEUVELMAN, Auteur ; Christina DALMAN, Auteur ; Michael LUNDBERG, Auteur ; Selma IDRING, Auteur ; Peter CARPENTER, Auteur ; Cecilia MAGNUSSON, Auteur ; Dheeraj RAI, Auteur Article en page(s) : p.308-318 Langues : Anglais (eng) Mots-clés : Anxiety  Autism spectrum disorder  Epidemiology  Intellectual disability  Mental health Index. décimale : PER Périodiques Résumé : Anxiety is common in children with ASD; however, the burden of specific anxiety disorders for adults with ASD is under-researched. Using the Stockholm Youth Cohort, we compared anxiety disorder diagnoses among autistic adults (n = 4049), with or without intellectual disability, and population controls (n = 217,645). We conducted additional sibling analyses. Anxiety disorders were diagnosed in 20.1% of adults with ASD compared with 8.7% of controls (RR = 2.62 [95% CI 2.47-2.79]), with greatest risk for autistic people without intellectual disability. Rates of almost all individual anxiety disorders were raised, notably obsessive-compulsive disorder and phobic anxiety disorders. Anxiety disorders were more common in full siblings and half-siblings of people with ASD. The implications of this are explored. En ligne : http://dx.doi.org/10.1007/s10803-019-04234-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=414 [article] Anxiety Disorders in Adults with Autism Spectrum Disorder: A Population-Based Study [Texte imprimé et/ou numérique] / Victoria NIMMO-SMITH, Auteur ; Hein HEUVELMAN, Auteur ; Christina DALMAN, Auteur ; Michael LUNDBERG, Auteur ; Selma IDRING, Auteur ; Peter CARPENTER, Auteur ; Cecilia MAGNUSSON, Auteur ; Dheeraj RAI, Auteur . - p.308-318. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 50-1 (January 2020) . - p.308-318 Mots-clés : Anxiety  Autism spectrum disorder  Epidemiology  Intellectual disability  Mental health Index. décimale : PER Périodiques Résumé : Anxiety is common in children with ASD; however, the burden of specific anxiety disorders for adults with ASD is under-researched. Using the Stockholm Youth Cohort, we compared anxiety disorder diagnoses among autistic adults (n = 4049), with or without intellectual disability, and population controls (n = 217,645). We conducted additional sibling analyses. Anxiety disorders were diagnosed in 20.1% of adults with ASD compared with 8.7% of controls (RR = 2.62 [95% CI 2.47-2.79]), with greatest risk for autistic people without intellectual disability. Rates of almost all individual anxiety disorders were raised, notably obsessive-compulsive disorder and phobic anxiety disorders. Anxiety disorders were more common in full siblings and half-siblings of people with ASD. The implications of this are explored. En ligne : http://dx.doi.org/10.1007/s10803-019-04234-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=414

Brief Report: Maternal Smoking During Pregnancy and Autism Spectrum Disorders / Brian K. LEE in Journal of Autism and Developmental Disorders, 42-9 (September 2012)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 42-9 (September 2012) . - p.2000-2005 Titre : Brief Report: Maternal Smoking During Pregnancy and Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Brian K. LEE, Auteur ; Renee M. GARDNER, Auteur ; Henrik DAL, Auteur ; Anna SVENSSON, Auteur ; Maria Rosaria GALANTI, Auteur ; Dheeraj RAI, Auteur ; Christina DALMAN, Auteur ; Cecilia MAGNUSSON, Auteur Année de publication : 2012 Article en page(s) : p.2000-2005 Langues : Anglais (eng) Mots-clés : Autism  Population register  Smoking  Sweden  Tobacco Index. décimale : PER Périodiques Résumé : Prenatal exposure to tobacco smoke is suggested as a potential risk factor for autism spectrum disorders (ASD). Previous epidemiological studies of this topic have yielded mixed findings. We performed a case–control study of 3,958 ASD cases and 38,983 controls nested in a large register-based cohort in Sweden. ASD case status was measured using a multisource case ascertainment system. In adjusted results, we found that maternal smoking during pregnancy is not associated with increased risk of ASD regardless of presence or absence of comorbid intellectual disability. Apparent associations were attributable to confounding by sociodemographic characteristics of parents such as education, income, and occupation. En ligne : http://dx.doi.org/10.1007/s10803-011-1425-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=180 [article] Brief Report: Maternal Smoking During Pregnancy and Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Brian K. LEE, Auteur ; Renee M. GARDNER, Auteur ; Henrik DAL, Auteur ; Anna SVENSSON, Auteur ; Maria Rosaria GALANTI, Auteur ; Dheeraj RAI, Auteur ; Christina DALMAN, Auteur ; Cecilia MAGNUSSON, Auteur . - 2012 . - p.2000-2005. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 42-9 (September 2012) . - p.2000-2005 Mots-clés : Autism  Population register  Smoking  Sweden  Tobacco Index. décimale : PER Périodiques Résumé : Prenatal exposure to tobacco smoke is suggested as a potential risk factor for autism spectrum disorders (ASD). Previous epidemiological studies of this topic have yielded mixed findings. We performed a case–control study of 3,958 ASD cases and 38,983 controls nested in a large register-based cohort in Sweden. ASD case status was measured using a multisource case ascertainment system. In adjusted results, we found that maternal smoking during pregnancy is not associated with increased risk of ASD regardless of presence or absence of comorbid intellectual disability. Apparent associations were attributable to confounding by sociodemographic characteristics of parents such as education, income, and occupation. En ligne : http://dx.doi.org/10.1007/s10803-011-1425-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=180

Changes in Prevalence of Autism Spectrum Disorders in 2001–2011: Findings from the Stockholm Youth Cohort / Selma IDRING in Journal of Autism and Developmental Disorders, 45-6 (June 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-6 (June 2015) . - p.1766-1773 Titre : Changes in Prevalence of Autism Spectrum Disorders in 2001–2011: Findings from the Stockholm Youth Cohort Type de document : Texte imprimé et/ou numérique Auteurs : Selma IDRING, Auteur ; Michael LUNDBERG, Auteur ; Harald STURM, Auteur ; Christina DALMAN, Auteur ; Clara GUMPERT, Auteur ; Dheeraj RAI, Auteur ; Brian K. LEE, Auteur ; Cecilia MAGNUSSON, Auteur Article en page(s) : p.1766-1773 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Intellectual disability  Prevalence  Time trend  Stockholm  Sweden Index. décimale : PER Périodiques Résumé : In a record-linkage study in Stockholm, Sweden, the year 2011 prevalence of diagnosed autism spectrum disorders (ASD) was found to be 0.40, 1.74, 2.46, and 1.76 % among 0–5, 6–12, 13–17, and 18–27 year olds, respectively. The corresponding proportion of cases with a recorded diagnosis of intellectual disability was 17.4, 22.1, 26.1 and 29.4 %. Between 2001 and 2011, ASD prevalence increased almost 3.5 fold among children aged 2–17 years. The increase was mainly accounted for by an eightfold increase of ASD without intellectual disability (from 0.14 to 1.10 %), while the prevalence of ASD with intellectual disability increased only slightly (from 0.28 to 0.34 %). The increase in ASD prevalence is likely contributed to by extrinsic factors such as increased awareness and diagnostics. En ligne : http://dx.doi.org/10.1007/s10803-014-2336-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=259 [article] Changes in Prevalence of Autism Spectrum Disorders in 2001–2011: Findings from the Stockholm Youth Cohort [Texte imprimé et/ou numérique] / Selma IDRING, Auteur ; Michael LUNDBERG, Auteur ; Harald STURM, Auteur ; Christina DALMAN, Auteur ; Clara GUMPERT, Auteur ; Dheeraj RAI, Auteur ; Brian K. LEE, Auteur ; Cecilia MAGNUSSON, Auteur . - p.1766-1773. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-6 (June 2015) . - p.1766-1773 Mots-clés : Autism spectrum disorders  Intellectual disability  Prevalence  Time trend  Stockholm  Sweden Index. décimale : PER Périodiques Résumé : In a record-linkage study in Stockholm, Sweden, the year 2011 prevalence of diagnosed autism spectrum disorders (ASD) was found to be 0.40, 1.74, 2.46, and 1.76 % among 0–5, 6–12, 13–17, and 18–27 year olds, respectively. The corresponding proportion of cases with a recorded diagnosis of intellectual disability was 17.4, 22.1, 26.1 and 29.4 %. Between 2001 and 2011, ASD prevalence increased almost 3.5 fold among children aged 2–17 years. The increase was mainly accounted for by an eightfold increase of ASD without intellectual disability (from 0.14 to 1.10 %), while the prevalence of ASD with intellectual disability increased only slightly (from 0.28 to 0.34 %). The increase in ASD prevalence is likely contributed to by extrinsic factors such as increased awareness and diagnostics. En ligne : http://dx.doi.org/10.1007/s10803-014-2336-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=259

Maternal hirsutism and autism spectrum disorders in offspring / Brian K. LEE in Autism Research, 10-9 (September 2017)  

Public ISBD [article]  inAutism Research > 10-9 (September 2017) . - p.1544-1546 Titre : Maternal hirsutism and autism spectrum disorders in offspring Type de document : Texte imprimé et/ou numérique Auteurs : Brian K. LEE, Auteur ; Stefan ARVER, Auteur ; Linnea WIDMAN, Auteur ; Renee M. GARDNER, Auteur ; Cecilia MAGNUSSON, Auteur ; Christina DALMAN, Auteur ; Kyriaki KOSIDOU, Auteur Article en page(s) : p.1544-1546 Langues : Anglais (eng) Mots-clés : epidemiology - analytic (risk factors)  pre- and perinatal risk factors  environmental risk factors Index. décimale : PER Périodiques Résumé : Because animal and human studies indicate that androgen exposure can influence neurodevelopment, it has been hypothesized that prenatal exposure to excess androgens may predispose to disorders with male-skewed ratio such as autism spectrum disorders (ASD). Therefore, maternal conditions characterized by hyperandrogenism such as polycystic ovary syndrome (PCOS) or hirsutism may be relevant to child ASD. We previously found in a large Swedish case-control study of 23,748 ASD cases and 208,796 matched controls that PCOS in mothers is associated with increased offspring risk of ASD. In the same sample, we have now examined whether maternal diagnoses of hirsutism were associated with ASD. In both unadjusted logistic regression models and models adjusted for a variety of covariates, hirsutism was associated with higher odds of ASD. The most adjusted odds ratios for associations with ASD for hirsutism diagnosis before birth and lifetime diagnosis of hirsutism were 1.64 (95% CI: 0.94, 2.83) and 1.26 (95% CI: 1.01, 1.57), respectively. The presence of an association of maternal hirsutism with child ASD is consistent with the hypothesis that androgens may be involved in the etiology of ASD. En ligne : http://dx.doi.org/10.1002/aur.1797 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=320 [article] Maternal hirsutism and autism spectrum disorders in offspring [Texte imprimé et/ou numérique] / Brian K. LEE, Auteur ; Stefan ARVER, Auteur ; Linnea WIDMAN, Auteur ; Renee M. GARDNER, Auteur ; Cecilia MAGNUSSON, Auteur ; Christina DALMAN, Auteur ; Kyriaki KOSIDOU, Auteur . - p.1544-1546. Langues : Anglais (eng) in Autism Research > 10-9 (September 2017) . - p.1544-1546 Mots-clés : epidemiology - analytic (risk factors)  pre- and perinatal risk factors  environmental risk factors Index. décimale : PER Périodiques Résumé : Because animal and human studies indicate that androgen exposure can influence neurodevelopment, it has been hypothesized that prenatal exposure to excess androgens may predispose to disorders with male-skewed ratio such as autism spectrum disorders (ASD). Therefore, maternal conditions characterized by hyperandrogenism such as polycystic ovary syndrome (PCOS) or hirsutism may be relevant to child ASD. We previously found in a large Swedish case-control study of 23,748 ASD cases and 208,796 matched controls that PCOS in mothers is associated with increased offspring risk of ASD. In the same sample, we have now examined whether maternal diagnoses of hirsutism were associated with ASD. In both unadjusted logistic regression models and models adjusted for a variety of covariates, hirsutism was associated with higher odds of ASD. The most adjusted odds ratios for associations with ASD for hirsutism diagnosis before birth and lifetime diagnosis of hirsutism were 1.64 (95% CI: 0.94, 2.83) and 1.26 (95% CI: 1.01, 1.57), respectively. The presence of an association of maternal hirsutism with child ASD is consistent with the hypothesis that androgens may be involved in the etiology of ASD. En ligne : http://dx.doi.org/10.1002/aur.1797 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=320

Qualification for upper secondary education in individuals with autism without intellectual disability: Total population study, Stockholm, Sweden / Isidora STARK in Autism, 25-4 (May 2021)  

Public ISBD [article]  inAutism > 25-4 (May 2021) . - p.1036-1046 Titre : Qualification for upper secondary education in individuals with autism without intellectual disability: Total population study, Stockholm, Sweden Type de document : Texte imprimé et/ou numérique Auteurs : Isidora STARK, Auteur ; Peiwen LIAO, Auteur ; Cecilia MAGNUSSON, Auteur ; Michael LUNDBERG, Auteur ; Dheeraj RAI, Auteur ; Anton LAGER, Auteur ; Selma IDRING NORDSTRÖM, Auteur Article en page(s) : p.1036-1046 Langues : Anglais (eng) Mots-clés : Attention-deficit hyperactivity disorder  autism  predictors  school outcome  total population cohort Index. décimale : PER Périodiques Résumé : Obtaining a quality education is important for any individual's chances of leading a healthy and thriving life. Currently, educational policies in many countries underscore the rights of students with autism to be educated in mainstream schools. While there is some knowledge on school outcomes among students with autism from older studies, little is known about rates of qualification for upper secondary education among children with autism in mainstream schools today. This lack of knowledge is problematic since autism is diagnosed more widely, and prior evidence may not be relevant for individuals with autism and their families today. Using Swedish registers, we therefore examined this in a study including all children and young people in Stockholm County in 2001 through 2011. We found that about two thirds of children with autism without intellectual disability qualified for upper secondary education at the expected age, in comparison with about nine in ten among typically developing peers. We also found that girls with autism had further difficulties obtaining such qualification than boys and that those who were additionally diagnosed with attention-deficit hyperactivity disorder were particularly at risk of non-qualification. Finally, students with autism without intellectual disability had a greater chance of completing compulsory education if given an extended period to graduate. These findings underline the need for supportive interventions for children with autism during compulsory school. They may also challenge the inclusive education policy adopted by majority of western countries, at least in the wake of addressing special needs in mainstream schooling. En ligne : http://dx.doi.org/10.1177/1362361320975929 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=444 [article] Qualification for upper secondary education in individuals with autism without intellectual disability: Total population study, Stockholm, Sweden [Texte imprimé et/ou numérique] / Isidora STARK, Auteur ; Peiwen LIAO, Auteur ; Cecilia MAGNUSSON, Auteur ; Michael LUNDBERG, Auteur ; Dheeraj RAI, Auteur ; Anton LAGER, Auteur ; Selma IDRING NORDSTRÖM, Auteur . - p.1036-1046. Langues : Anglais (eng) in Autism > 25-4 (May 2021) . - p.1036-1046 Mots-clés : Attention-deficit hyperactivity disorder  autism  predictors  school outcome  total population cohort Index. décimale : PER Périodiques Résumé : Obtaining a quality education is important for any individual's chances of leading a healthy and thriving life. Currently, educational policies in many countries underscore the rights of students with autism to be educated in mainstream schools. While there is some knowledge on school outcomes among students with autism from older studies, little is known about rates of qualification for upper secondary education among children with autism in mainstream schools today. This lack of knowledge is problematic since autism is diagnosed more widely, and prior evidence may not be relevant for individuals with autism and their families today. Using Swedish registers, we therefore examined this in a study including all children and young people in Stockholm County in 2001 through 2011. We found that about two thirds of children with autism without intellectual disability qualified for upper secondary education at the expected age, in comparison with about nine in ten among typically developing peers. We also found that girls with autism had further difficulties obtaining such qualification than boys and that those who were additionally diagnosed with attention-deficit hyperactivity disorder were particularly at risk of non-qualification. Finally, students with autism without intellectual disability had a greater chance of completing compulsory education if given an extended period to graduate. These findings underline the need for supportive interventions for children with autism during compulsory school. They may also challenge the inclusive education policy adopted by majority of western countries, at least in the wake of addressing special needs in mainstream schooling. En ligne : http://dx.doi.org/10.1177/1362361320975929 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=444

The Familial Risk of Autism Spectrum Disorder with and without Intellectual Disability / Sherlly XIE in Autism Research, 13-12 (December 2020)  

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