Abnormal wiring of the connectome in adults with high-functioning autism spectrum disorder / Ulrika ROINE in Molecular Autism, (December 2015)  

Public ISBD [article]  inMolecular Autism > (December 2015) . - p.1-11 Titre : Abnormal wiring of the connectome in adults with high-functioning autism spectrum disorder Type de document : texte imprimé Auteurs : Ulrika ROINE, Auteur ; Timo ROINE, Auteur ; Juha SALMI, Auteur ; Taina NIEMINEN-VON WENDT, Auteur ; Pekka TANI, Auteur ; Sami LEPPAMAKI, Auteur ; Pertti RINTAHAKA, Auteur ; Karen CAEYENBERGHS, Auteur ; Alexander LEEMANS, Auteur ; Mikko SAMS, Auteur Article en page(s) : p.1-11 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Recent brain imaging findings suggest that there are widely distributed abnormalities affecting the brain connectivity in individuals with autism spectrum disorder (ASD). Using graph theoretical analysis, it is possible to investigate both global and local properties of brain’s wiring diagram, i.e., the connectome. En ligne : http://dx.doi.org/10.1186/s13229-015-0058-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277 [article] Abnormal wiring of the connectome in adults with high-functioning autism spectrum disorder [texte imprimé] / Ulrika ROINE, Auteur ; Timo ROINE, Auteur ; Juha SALMI, Auteur ; Taina NIEMINEN-VON WENDT, Auteur ; Pekka TANI, Auteur ; Sami LEPPAMAKI, Auteur ; Pertti RINTAHAKA, Auteur ; Karen CAEYENBERGHS, Auteur ; Alexander LEEMANS, Auteur ; Mikko SAMS, Auteur . - p.1-11. Langues : Anglais (eng) in Molecular Autism > (December 2015) . - p.1-11 Index. décimale : PER Périodiques Résumé : Recent brain imaging findings suggest that there are widely distributed abnormalities affecting the brain connectivity in individuals with autism spectrum disorder (ASD). Using graph theoretical analysis, it is possible to investigate both global and local properties of brain’s wiring diagram, i.e., the connectome. En ligne : http://dx.doi.org/10.1186/s13229-015-0058-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277

Audiovisual Speech Perception and Eye Gaze Behavior of Adults with Asperger Syndrome / Satu SAALASTI in Journal of Autism and Developmental Disorders, 42-8 (August 2012)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 42-8 (August 2012) . - p.1606-1615 Titre : Audiovisual Speech Perception and Eye Gaze Behavior of Adults with Asperger Syndrome Type de document : texte imprimé Auteurs : Satu SAALASTI, Auteur ; Jari V. KATSYRI, Auteur ; Kaisa TIIPPANA, Auteur ; Mari LAINE-HERNANDEZ, Auteur ; Lennart VON WENDT, Auteur ; Mikko SAMS, Auteur Année de publication : 2012 Article en page(s) : p.1606-1615 Langues : Anglais (eng) Mots-clés : Asperger syndrome  Autism spectrum disorders  Multisensory integration  Audiovisual speech  Eye gaze behavior  Perception Index. décimale : PER Périodiques Résumé : Audiovisual speech perception was studied in adults with Asperger syndrome (AS), by utilizing the McGurk effect, in which conflicting visual articulation alters the perception of heard speech. The AS group perceived the audiovisual stimuli differently from age, sex and IQ matched controls. When a voice saying /p/ was presented with a face articulating /k/, the controls predominantly heard /k/. Instead, the AS group heard /k/ and /t/ with almost equal frequency, but with large differences between individuals. There were no differences in gaze direction or unisensory perception between the AS and control participants that could have contributed to the audiovisual differences. We suggest an explanation in terms of weak support from the motor system for audiovisual speech perception in AS. En ligne : http://dx.doi.org/10.1007/s10803-011-1400-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=178 [article] Audiovisual Speech Perception and Eye Gaze Behavior of Adults with Asperger Syndrome [texte imprimé] / Satu SAALASTI, Auteur ; Jari V. KATSYRI, Auteur ; Kaisa TIIPPANA, Auteur ; Mari LAINE-HERNANDEZ, Auteur ; Lennart VON WENDT, Auteur ; Mikko SAMS, Auteur . - 2012 . - p.1606-1615. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 42-8 (August 2012) . - p.1606-1615 Mots-clés : Asperger syndrome  Autism spectrum disorders  Multisensory integration  Audiovisual speech  Eye gaze behavior  Perception Index. décimale : PER Périodiques Résumé : Audiovisual speech perception was studied in adults with Asperger syndrome (AS), by utilizing the McGurk effect, in which conflicting visual articulation alters the perception of heard speech. The AS group perceived the audiovisual stimuli differently from age, sex and IQ matched controls. When a voice saying /p/ was presented with a face articulating /k/, the controls predominantly heard /k/. Instead, the AS group heard /k/ and /t/ with almost equal frequency, but with large differences between individuals. There were no differences in gaze direction or unisensory perception between the AS and control participants that could have contributed to the audiovisual differences. We suggest an explanation in terms of weak support from the motor system for audiovisual speech perception in AS. En ligne : http://dx.doi.org/10.1007/s10803-011-1400-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=178

Constrained spherical deconvolution-based tractography and tract-based spatial statistics show abnormal microstructural organization in Asperger syndrome / Ulrika ROINE in Molecular Autism, (January 2015)  

Public ISBD [article]  inMolecular Autism > (January 2015) . - p.1-12 Titre : Constrained spherical deconvolution-based tractography and tract-based spatial statistics show abnormal microstructural organization in Asperger syndrome Type de document : texte imprimé Auteurs : Ulrika ROINE, Auteur ; Juha SALMI, Auteur ; Timo ROINE, Auteur ; Taina Nieminen-von WENDT, Auteur ; Sami LEPPAMAKI, Auteur ; Pertti RINTAHAKA, Auteur ; Pekka TANI, Auteur ; Alexander LEEMANS, Auteur ; Mikko SAMS, Auteur Article en page(s) : p.1-12 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The aim of this study was to investigate potential differences in neural structure in individuals with Asperger syndrome (AS), high-functioning individuals with autism spectrum disorder (ASD). The main symptoms of AS are severe impairments in social interactions and restricted or repetitive patterns of behaviors, interests or activities. En ligne : http://dx.doi.org/10.1186/2040-2392-6-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277 [article] Constrained spherical deconvolution-based tractography and tract-based spatial statistics show abnormal microstructural organization in Asperger syndrome [texte imprimé] / Ulrika ROINE, Auteur ; Juha SALMI, Auteur ; Timo ROINE, Auteur ; Taina Nieminen-von WENDT, Auteur ; Sami LEPPAMAKI, Auteur ; Pertti RINTAHAKA, Auteur ; Pekka TANI, Auteur ; Alexander LEEMANS, Auteur ; Mikko SAMS, Auteur . - p.1-12. Langues : Anglais (eng) in Molecular Autism > (January 2015) . - p.1-12 Index. décimale : PER Périodiques Résumé : The aim of this study was to investigate potential differences in neural structure in individuals with Asperger syndrome (AS), high-functioning individuals with autism spectrum disorder (ASD). The main symptoms of AS are severe impairments in social interactions and restricted or repetitive patterns of behaviors, interests or activities. En ligne : http://dx.doi.org/10.1186/2040-2392-6-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277

Increased Coherence of White Matter Fiber Tract Organization in Adults with Asperger Syndrome: A Diffusion Tensor Imaging Study / Ulrika ROINE in Autism Research, 6-6 (December 2013)  

Public ISBD [article]  inAutism Research > 6-6 (December 2013) . - p.642-650 Titre : Increased Coherence of White Matter Fiber Tract Organization in Adults with Asperger Syndrome: A Diffusion Tensor Imaging Study Type de document : texte imprimé Auteurs : Ulrika ROINE, Auteur ; Timo ROINE, Auteur ; Juha SALMI, Auteur ; Taina NIEMINEN-VON WENDT, Auteur ; Sami LEPPAMAKI, Auteur ; Pertti RINTAHAKA, Auteur ; Pekka TANI, Auteur ; Alexander LEEMANS, Auteur ; Mikko SAMS, Auteur Année de publication : 2013 Article en page(s) : p.642-650 Langues : Anglais (eng) Mots-clés : diffusion tensor imaging (DTI)  clinical psychiatry  neuroimaging  autism spectrum disorder Index. décimale : PER Périodiques Résumé : To investigate whether there are global white matter (WM) differences between autistic and healthy adults, we performed diffusion tensor imaging (DTI) in 14 male adults with Asperger syndrome (AS) and 19 gender-, age-, and intelligence quotient-matched controls. We focused on individuals with high-functioning autism spectrum disorder (ASD), AS, to decrease heterogeneity caused by large variation in the cognitive profile. Previous DTI studies of ASD have mainly focused on finding local changes in fractional anisotropy (FA) and mean diffusivity (MD), two indexes used to characterize microstructural properties of WM. Although the local or voxel-based approaches may be able to provide detailed information in terms of location of the observed differences, such results are known to be highly sensitive to partial volume effects, registration errors, or placement of the regions of interest. Therefore, we performed global histogram analyses of (a) whole-brain tractography results and (b) skeletonized WM masks. In addition to the FA and MD, the planar diffusion coefficient (CP) was computed as it can provide more specific information of the complexity of the neural structure. Our main finding indicated that adults with AS had higher mean FA values than controls. A less complex neural structure in adults with AS could have explained the results, but no significant difference in CP was found. Our results suggest that there are global abnormalities in the WM tissue of adults with AS. En ligne : http://dx.doi.org/10.1002/aur.1332 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=221 [article] Increased Coherence of White Matter Fiber Tract Organization in Adults with Asperger Syndrome: A Diffusion Tensor Imaging Study [texte imprimé] / Ulrika ROINE, Auteur ; Timo ROINE, Auteur ; Juha SALMI, Auteur ; Taina NIEMINEN-VON WENDT, Auteur ; Sami LEPPAMAKI, Auteur ; Pertti RINTAHAKA, Auteur ; Pekka TANI, Auteur ; Alexander LEEMANS, Auteur ; Mikko SAMS, Auteur . - 2013 . - p.642-650. Langues : Anglais (eng) in Autism Research > 6-6 (December 2013) . - p.642-650 Mots-clés : diffusion tensor imaging (DTI)  clinical psychiatry  neuroimaging  autism spectrum disorder Index. décimale : PER Périodiques Résumé : To investigate whether there are global white matter (WM) differences between autistic and healthy adults, we performed diffusion tensor imaging (DTI) in 14 male adults with Asperger syndrome (AS) and 19 gender-, age-, and intelligence quotient-matched controls. We focused on individuals with high-functioning autism spectrum disorder (ASD), AS, to decrease heterogeneity caused by large variation in the cognitive profile. Previous DTI studies of ASD have mainly focused on finding local changes in fractional anisotropy (FA) and mean diffusivity (MD), two indexes used to characterize microstructural properties of WM. Although the local or voxel-based approaches may be able to provide detailed information in terms of location of the observed differences, such results are known to be highly sensitive to partial volume effects, registration errors, or placement of the regions of interest. Therefore, we performed global histogram analyses of (a) whole-brain tractography results and (b) skeletonized WM masks. In addition to the FA and MD, the planar diffusion coefficient (CP) was computed as it can provide more specific information of the complexity of the neural structure. Our main finding indicated that adults with AS had higher mean FA values than controls. A less complex neural structure in adults with AS could have explained the results, but no significant difference in CP was found. Our results suggest that there are global abnormalities in the WM tissue of adults with AS. En ligne : http://dx.doi.org/10.1002/aur.1332 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=221

Valence Scaling of Dynamic Facial Expressions is Altered in High-Functioning Subjects with Autism Spectrum Disorders: an fMRI Study / Jukka S. RAHKO in Journal of Autism and Developmental Disorders, 42-6 (June 2012)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 42-6 (June 2012) . - p.1011-1024 Titre : Valence Scaling of Dynamic Facial Expressions is Altered in High-Functioning Subjects with Autism Spectrum Disorders: an fMRI Study Type de document : texte imprimé Auteurs : Jukka S. RAHKO, Auteur ; Jyri-Johan PAAKKI, Auteur ; Tuomo H. STARCK, Auteur ; Juha NIKKINEN, Auteur ; David L. PAULS, Auteur ; Jari V. KATSYRI, Auteur ; Eira JANSSON-VERKASALO, Auteur ; Alice S. CARTER, Auteur ; Tuula HURTIG, Auteur ; Marja-Leena MATTILA, Auteur ; Katja JUSSILA, Auteur ; Jukka J. REMES, Auteur ; Sanna KUUSIKKO-GAUFFIN, Auteur ; Mikko SAMS, Auteur ; Sven BÖLTE, Auteur ; Hanna EBELING, Auteur ; Irma MOILANEN, Auteur ; Osmo TERVONEN, Auteur ; Vesa KIVINIEMI, Auteur Année de publication : 2012 Article en page(s) : p.1011-1024 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Emotional facial expressions  Face processing  Functional MRI  Mirror neuron system  Valence Index. décimale : PER Périodiques Résumé : FMRI was performed with the dynamic facial expressions fear and happiness. This was done to detect differences in valence processing between 25 subjects with autism spectrum disorders (ASDs) and 27 typically developing controls. Valence scaling was abnormal in ASDs. Positive valence induces lower deactivation and abnormally strong activity in ASD in multiple regions. Negative valence increased deactivation in visual areas in subjects with ASDs. The most marked differences between valences focus on fronto-insular and temporal regions. This supports the idea that subjects with ASDs may have difficulty in passive processing of the salience and mirroring of expressions. When the valence scaling of brain activity fails, in contrast to controls, these areas activate and/or deactivate inappropriately during facial stimuli presented dynamically. En ligne : http://dx.doi.org/10.1007/s10803-011-1332-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=156 [article] Valence Scaling of Dynamic Facial Expressions is Altered in High-Functioning Subjects with Autism Spectrum Disorders: an fMRI Study [texte imprimé] / Jukka S. RAHKO, Auteur ; Jyri-Johan PAAKKI, Auteur ; Tuomo H. STARCK, Auteur ; Juha NIKKINEN, Auteur ; David L. PAULS, Auteur ; Jari V. KATSYRI, Auteur ; Eira JANSSON-VERKASALO, Auteur ; Alice S. CARTER, Auteur ; Tuula HURTIG, Auteur ; Marja-Leena MATTILA, Auteur ; Katja JUSSILA, Auteur ; Jukka J. REMES, Auteur ; Sanna KUUSIKKO-GAUFFIN, Auteur ; Mikko SAMS, Auteur ; Sven BÖLTE, Auteur ; Hanna EBELING, Auteur ; Irma MOILANEN, Auteur ; Osmo TERVONEN, Auteur ; Vesa KIVINIEMI, Auteur . - 2012 . - p.1011-1024. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 42-6 (June 2012) . - p.1011-1024 Mots-clés : Autism spectrum disorders  Emotional facial expressions  Face processing  Functional MRI  Mirror neuron system  Valence Index. décimale : PER Périodiques Résumé : FMRI was performed with the dynamic facial expressions fear and happiness. This was done to detect differences in valence processing between 25 subjects with autism spectrum disorders (ASDs) and 27 typically developing controls. Valence scaling was abnormal in ASDs. Positive valence induces lower deactivation and abnormally strong activity in ASD in multiple regions. Negative valence increased deactivation in visual areas in subjects with ASDs. The most marked differences between valences focus on fronto-insular and temporal regions. This supports the idea that subjects with ASDs may have difficulty in passive processing of the salience and mirroring of expressions. When the valence scaling of brain activity fails, in contrast to controls, these areas activate and/or deactivate inappropriately during facial stimuli presented dynamically. En ligne : http://dx.doi.org/10.1007/s10803-011-1332-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=156

---

1 (1 - 5 / 5) Par page : 25 50 100 200