Auditory processing in autism spectrum disorder: Mismatch negativity deficits / Chantal VLASKAMP in Autism Research, 10-11 (November 2017)  

Public ISBD [article]  inAutism Research > 10-11 (November 2017) . - p.1857-1865 Titre : Auditory processing in autism spectrum disorder: Mismatch negativity deficits Type de document : Texte imprimé et/ou numérique Auteurs : Chantal VLASKAMP, Auteur ; Bob ORANJE, Auteur ; Gitte Falcher MADSEN, Auteur ; Jens Richardt MØLLEGAARD JEPSEN, Auteur ; Sarah DURSTON, Auteur ; Cathriona CANTIO, Auteur ; Birte GLENTHØJ, Auteur ; Niels BILENBERG, Auteur Article en page(s) : p.1857-1865 Langues : Anglais (eng) Mots-clés : auditory processing  ASD  MMN  P3a  schizophrenia Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorders (ASD) often show changes in (automatic) auditory processing. Electrophysiology provides a method to study auditory processing, by investigating event-related potentials such as mismatch negativity (MMN) and P3a-amplitude. However, findings on MMN in autism are highly inconsistent, partly due to small sample sizes in the studies and differences in MMN paradigms. Therefore, in the current study, MMN and P3a amplitude were assessed in a relatively large sample of children with ASD, using a more extensive MMN paradigm and compared with that of typically developing children (TDC). Thirty-five children (aged 8–12 years) with ASD and 38 age and gender matched TDC were assessed with a MMN paradigm with three types of deviants, i.e., frequency, duration and a combination of these two. MMN elicited by duration and frequency-duration deviants was significantly reduced in the ASD group. P3a-amplitude elicited by duration deviants was significantly increased in the ASD group. Reduced MMN in children with ASD suggests that children with ASD may be less responsive to environmentally deviant stimuli at an early (sensory) level. P3a-amplitude was increased in ASD, implying a hyper-responsivity at the attentional level. In addition, as similar MMN deficits are found in schizophrenia, these MMN results may explain some of the frequently reported increased risk of children with ASD to develop schizophrenia later in life. Autism Res 2017, 10: 1857–1865. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. Lay Summary Automatic detection of deviant sounds in the environment, such as upcoming traffic, is often affected in children with autism spectrum disorders (ASD). Mismatch negativity (MMN) is a way to quantify automatic deviancy detection, using electroencephalography. In this study, auditory MMN was assessed in 35 children with ASD and 38 matched control children, revealing significantly reduced MMN in the ASD group. This may indicate that children with ASD are less able to automatically detect environmentally deviant stimuli. En ligne : http://dx.doi.org/10.1002/aur.1821 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322 [article] Auditory processing in autism spectrum disorder: Mismatch negativity deficits [Texte imprimé et/ou numérique] / Chantal VLASKAMP, Auteur ; Bob ORANJE, Auteur ; Gitte Falcher MADSEN, Auteur ; Jens Richardt MØLLEGAARD JEPSEN, Auteur ; Sarah DURSTON, Auteur ; Cathriona CANTIO, Auteur ; Birte GLENTHØJ, Auteur ; Niels BILENBERG, Auteur . - p.1857-1865. Langues : Anglais (eng) in Autism Research > 10-11 (November 2017) . - p.1857-1865 Mots-clés : auditory processing  ASD  MMN  P3a  schizophrenia Index. décimale : PER Périodiques Résumé : Children with autism spectrum disorders (ASD) often show changes in (automatic) auditory processing. Electrophysiology provides a method to study auditory processing, by investigating event-related potentials such as mismatch negativity (MMN) and P3a-amplitude. However, findings on MMN in autism are highly inconsistent, partly due to small sample sizes in the studies and differences in MMN paradigms. Therefore, in the current study, MMN and P3a amplitude were assessed in a relatively large sample of children with ASD, using a more extensive MMN paradigm and compared with that of typically developing children (TDC). Thirty-five children (aged 8–12 years) with ASD and 38 age and gender matched TDC were assessed with a MMN paradigm with three types of deviants, i.e., frequency, duration and a combination of these two. MMN elicited by duration and frequency-duration deviants was significantly reduced in the ASD group. P3a-amplitude elicited by duration deviants was significantly increased in the ASD group. Reduced MMN in children with ASD suggests that children with ASD may be less responsive to environmentally deviant stimuli at an early (sensory) level. P3a-amplitude was increased in ASD, implying a hyper-responsivity at the attentional level. In addition, as similar MMN deficits are found in schizophrenia, these MMN results may explain some of the frequently reported increased risk of children with ASD to develop schizophrenia later in life. Autism Res 2017, 10: 1857–1865. © 2017 International Society for Autism Research, Wiley Periodicals, Inc. Lay Summary Automatic detection of deviant sounds in the environment, such as upcoming traffic, is often affected in children with autism spectrum disorders (ASD). Mismatch negativity (MMN) is a way to quantify automatic deviancy detection, using electroencephalography. In this study, auditory MMN was assessed in 35 children with ASD and 38 matched control children, revealing significantly reduced MMN in the ASD group. This may indicate that children with ASD are less able to automatically detect environmentally deviant stimuli. En ligne : http://dx.doi.org/10.1002/aur.1821 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=322

Digital Interventions for Autism Spectrum Disorder: A Meta-analysis / H. SANDGREEN in Journal of Autism and Developmental Disorders, 51-9 (September 2021)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 51-9 (September 2021) . - p.3138-3152 Titre : Digital Interventions for Autism Spectrum Disorder: A Meta-analysis Type de document : Texte imprimé et/ou numérique Auteurs : H. SANDGREEN, Auteur ; L. H. FREDERIKSEN, Auteur ; Niels BILENBERG, Auteur Article en page(s) : p.3138-3152 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/therapy  Humans  Social Skills  Software  Technology  Autism  Computer  Digital  Meta-analysis  Systematic review Index. décimale : PER Périodiques Résumé : This study aimed to review digital interventions in the treatment of autism spectrum disorder (ASD). A systematic review and meta-analysis was conducted. Nineteen studies were included. The interventions aimed to improve social skills (n?=?11), developmental skills (n?=?2) and 6 other different targets. Technology used were computer programs (n?=?14), tablet apps (n?=?3), a robot (n?=?1) and an interactive DVD (n?=?1). The meta-analysis resulted in an overall effect size (Cohen's d) of 0.32 [0.12-0.51], indicating a small effect. Heterogeneity between studies was high (I(2)?=?100%), limiting the generalization of results. Therefore, we recommend larger RCT studies, and guidelines for the development of trials evaluating digital interventions for ASD, for making comparison of future studies possible.Registration can be found online at Prospero: https://www.crd.york.ac.uk/prospero/ , registration no. CRD42020146542. En ligne : http://dx.doi.org/10.1007/s10803-020-04778-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=453 [article] Digital Interventions for Autism Spectrum Disorder: A Meta-analysis [Texte imprimé et/ou numérique] / H. SANDGREEN, Auteur ; L. H. FREDERIKSEN, Auteur ; Niels BILENBERG, Auteur . - p.3138-3152. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 51-9 (September 2021) . - p.3138-3152 Mots-clés : Autism Spectrum Disorder/therapy  Humans  Social Skills  Software  Technology  Autism  Computer  Digital  Meta-analysis  Systematic review Index. décimale : PER Périodiques Résumé : This study aimed to review digital interventions in the treatment of autism spectrum disorder (ASD). A systematic review and meta-analysis was conducted. Nineteen studies were included. The interventions aimed to improve social skills (n?=?11), developmental skills (n?=?2) and 6 other different targets. Technology used were computer programs (n?=?14), tablet apps (n?=?3), a robot (n?=?1) and an interactive DVD (n?=?1). The meta-analysis resulted in an overall effect size (Cohen's d) of 0.32 [0.12-0.51], indicating a small effect. Heterogeneity between studies was high (I(2)?=?100%), limiting the generalization of results. Therefore, we recommend larger RCT studies, and guidelines for the development of trials evaluating digital interventions for ASD, for making comparison of future studies possible.Registration can be found online at Prospero: https://www.crd.york.ac.uk/prospero/ , registration no. CRD42020146542. En ligne : http://dx.doi.org/10.1007/s10803-020-04778-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=453

Do cognitive deficits persist into adolescence in autism? / Cathriona CANTIO in Autism Research, 11-9 (September 2018)  

Public ISBD [article]  inAutism Research > 11-9 (September 2018) . - p.1229-1238 Titre : Do cognitive deficits persist into adolescence in autism? Type de document : Texte imprimé et/ou numérique Auteurs : Cathriona CANTIO, Auteur ; S. WHITE, Auteur ; G. F. MADSEN, Auteur ; Niels BILENBERG, Auteur ; Jens Richardt MØLLEGAARD JEPSEN, Auteur Article en page(s) : p.1229-1238 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  adolescent development  cognition  executive function  theory of mind Index. décimale : PER Périodiques Résumé : SEVERAL THEORIES HAVE ATTEMPTED TO CHARACTERISE AUTISM SPECTRUM DISORDERS (ASDS) AT THE COGNITIVE LEVEL, MOST NOTABLY: THEORY OF MIND (TOM), EXECUTIVE FUNCTION (EF), AND A LOCAL PROCESSING BIAS (LB). THE AIM OF THIS STUDY WAS TO INVESTIGATE HOW THESE COGNITIVE FUNCTIONS DEVELOP OVER TIME: The three cognitive domains (ToM, EF, and LB) were examined in a group of high-functioning children (age: 8-12, mean 10.85; IQ: 78-139, mean 105.48) with ASD and a matched group of children with neurotypical development (NTD) (IQ: 75-145, mean: 109.47), and several tasks were used within each domain to ensure the validity of the cognitive measures. Approximately 3 years later (mean age: 14.34), all children and their families were invited to participate in the follow-up (ASD, N = 21; NTD, N = 30). While the understanding of other's minds does improve from childhood to adolescence, ToM impairment persists in adolescents with ASD relative to their peers. Likewise, a development in EF was observed in the ASD group, while no significant improvement was seen in the NTD group, leading the ASD group to catch up in this domain. We did not detect any group differences at any time point regarding local bias processing (LB). Individual patterns of development were seen, but remarkably, ToM deficits were present in every child with ASD in whom we could detect any cognitive impairment at baseline, and a similar pattern was found at follow-up. These findings indicate that ToM is a persistent cognitive deficit in ASD. Autism Res 2018, 11: 1229-1238. (c) 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: This was the first study to investigate the development of three well-known cognitive functions into adolescence: While the understanding of other's minds improves from childhood to adolescence, adolescents with ASD are still impaired relative to their peers. The EFs, however, seem to improve to a neurotypical level in ASD as children enter adolescence, while local processing bias seems to differentiate the groups only in early childhood. En ligne : http://dx.doi.org/10.1002/aur.1976 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=369 [article] Do cognitive deficits persist into adolescence in autism? [Texte imprimé et/ou numérique] / Cathriona CANTIO, Auteur ; S. WHITE, Auteur ; G. F. MADSEN, Auteur ; Niels BILENBERG, Auteur ; Jens Richardt MØLLEGAARD JEPSEN, Auteur . - p.1229-1238. Langues : Anglais (eng) in Autism Research > 11-9 (September 2018) . - p.1229-1238 Mots-clés : Autism spectrum disorders  adolescent development  cognition  executive function  theory of mind Index. décimale : PER Périodiques Résumé : SEVERAL THEORIES HAVE ATTEMPTED TO CHARACTERISE AUTISM SPECTRUM DISORDERS (ASDS) AT THE COGNITIVE LEVEL, MOST NOTABLY: THEORY OF MIND (TOM), EXECUTIVE FUNCTION (EF), AND A LOCAL PROCESSING BIAS (LB). THE AIM OF THIS STUDY WAS TO INVESTIGATE HOW THESE COGNITIVE FUNCTIONS DEVELOP OVER TIME: The three cognitive domains (ToM, EF, and LB) were examined in a group of high-functioning children (age: 8-12, mean 10.85; IQ: 78-139, mean 105.48) with ASD and a matched group of children with neurotypical development (NTD) (IQ: 75-145, mean: 109.47), and several tasks were used within each domain to ensure the validity of the cognitive measures. Approximately 3 years later (mean age: 14.34), all children and their families were invited to participate in the follow-up (ASD, N = 21; NTD, N = 30). While the understanding of other's minds does improve from childhood to adolescence, ToM impairment persists in adolescents with ASD relative to their peers. Likewise, a development in EF was observed in the ASD group, while no significant improvement was seen in the NTD group, leading the ASD group to catch up in this domain. We did not detect any group differences at any time point regarding local bias processing (LB). Individual patterns of development were seen, but remarkably, ToM deficits were present in every child with ASD in whom we could detect any cognitive impairment at baseline, and a similar pattern was found at follow-up. These findings indicate that ToM is a persistent cognitive deficit in ASD. Autism Res 2018, 11: 1229-1238. (c) 2018 International Society for Autism Research, Wiley Periodicals, Inc. LAY SUMMARY: This was the first study to investigate the development of three well-known cognitive functions into adolescence: While the understanding of other's minds improves from childhood to adolescence, adolescents with ASD are still impaired relative to their peers. The EFs, however, seem to improve to a neurotypical level in ASD as children enter adolescence, while local processing bias seems to differentiate the groups only in early childhood. En ligne : http://dx.doi.org/10.1002/aur.1976 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=369

Effects of individual differences, society, and culture on youth-rated problems and strengths in 38 societies / Masha Y. IVANOVA in Journal of Child Psychology and Psychiatry, 63-11 (November 2022)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 63-11 (November 2022) . - p.1297-1307 Titre : Effects of individual differences, society, and culture on youth-rated problems and strengths in 38 societies Type de document : Texte imprimé et/ou numérique Auteurs : Masha Y. IVANOVA, Auteur ; Thomas M. ACHENBACH, Auteur ; Lori TURNER, Auteur ; Fredrik ALMQVIST, Auteur ; Ivan BEGOVAC, Auteur ; Niels BILENBERG, Auteur ; Hector BIRD, Auteur ; Anders G. BROBERG, Auteur ; Mery A. CORDOVA CALDERON, Auteur ; Myriam CHAHED, Auteur ; Hoang-Minh DANG, Auteur ; Anca DOBREAN, Auteur ; Mandred DOPFNER, Auteur ; Nese EROL, Auteur ; Maria FORNS, Auteur ; Halldor S. GUOMUNDSSON, Auteur ; Helga HANNESDOTTIR, Auteur ; Nohelia HEWITT-RAMIREZ, Auteur ; Yasuko KANBAYASHI, Auteur ; Suyen KARKI, Auteur ; Hans M. KOOT, Auteur ; Michael C. LAMBERT, Auteur ; Patrick LEUNG, Auteur ; Dorcas N. MAGAI, Auteur ; Alfio MAGGIOLINI, Auteur ; Christa Winkler METZKE, Auteur ; Asghar MINAEI, Auteur ; Marina MONZANI DA ROCHA, Auteur ; Paulo A. S. MOREIRA, Auteur ; Mesfin S. MULATU, Auteur ; Torunn Stene NØVIK, Auteur ; Kyung Ja OH, Auteur ; Djaouida PETOT, Auteur ; Jean-Michel PETOT, Auteur ; Cecilia PISA, Auteur ; Rolando POMALIMA, Auteur ; Alexandra ROUSSOS, Auteur ; Vlasta RUDAN, Auteur ; Michael G. SAWYER, Auteur ; Mimoza SHAHINI, Auteur ; Zeynep SIMSEK, Auteur ; Hans-Christoph STEINHAUSEN, Auteur ; Frank C. VERHULST, Auteur ; Sheila WEINTRAUB, Auteur ; Bahr WEISS, Auteur ; Tomasz WOLANCZYK, Auteur ; Eugene Yuqing ZHANG, Auteur ; Nelly ZILBER, Auteur ; Rita ÅOEUKAUSKIENÄ–, Auteur Article en page(s) : p.1297-1307 Langues : Anglais (eng) Mots-clés : Child  Adolescent  Humans  Individuality  Parents/psychology  Self Report  Individual differences  Youth Self-Report  multicultural  psychopathology  strengths Index. décimale : PER Périodiques Résumé : BACKGROUND: Clinicians increasingly serve youths from societal/cultural backgrounds different from their own. This raises questions about how to interpret what such youths report. Rescorla et al. (2019, European Child & Adolescent Psychiatry, 28, 1107) found that much more variance in 72,493 parents' ratings of their offspring's mental health problems was accounted for by individual differences than by societal or cultural differences. Although parents' reports are essential for clinical assessment of their offspring, they reflect parents' perceptions of the offspring. Consequently, clinical assessment also requires self-reports from the offspring themselves. To test effects of individual differences, society, and culture on youths' self-ratings of their problems and strengths, we analyzed Youth Self-Report (YSR) scores for 39,849 11-17 year olds in 38 societies. METHODS: Indigenous researchers obtained YSR self-ratings from population samples of youths in 38 societies representing 10 culture cluster identified in the Global Leadership and Organizational Behavioral Effectiveness study. Hierarchical linear modeling of scores on 17 problem scales and one strengths scale estimated the percent of variance accounted for by individual differences (including measurement error), society, and culture cluster. ANOVAs tested age and gender effects. RESULTS: Averaged across the 17 problem scales, individual differences accounted for 92.5% of variance, societal differences 6.0%, and cultural differences 1.5%. For strengths, individual differences accounted for 83.4% of variance, societal differences 10.1%, and cultural differences 6.5%. Age and gender had very small effects. CONCLUSIONS: Like parents' ratings, youths' self-ratings of problems were affected much more by individual differences than societal/cultural differences. Most variance in self-rated strengths also reflected individual differences, but societal/cultural effects were larger than for problems, suggesting greater influence of social desirability. The clinical significance of individual differences in youths' self-reports should thus not be minimized by societal/cultural differences, which-while important-can be taken into account with appropriate norms, as can gender and age differences. En ligne : http://dx.doi.org/10.1111/jcpp.13569 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490 [article] Effects of individual differences, society, and culture on youth-rated problems and strengths in 38 societies [Texte imprimé et/ou numérique] / Masha Y. IVANOVA, Auteur ; Thomas M. ACHENBACH, Auteur ; Lori TURNER, Auteur ; Fredrik ALMQVIST, Auteur ; Ivan BEGOVAC, Auteur ; Niels BILENBERG, Auteur ; Hector BIRD, Auteur ; Anders G. BROBERG, Auteur ; Mery A. CORDOVA CALDERON, Auteur ; Myriam CHAHED, Auteur ; Hoang-Minh DANG, Auteur ; Anca DOBREAN, Auteur ; Mandred DOPFNER, Auteur ; Nese EROL, Auteur ; Maria FORNS, Auteur ; Halldor S. GUOMUNDSSON, Auteur ; Helga HANNESDOTTIR, Auteur ; Nohelia HEWITT-RAMIREZ, Auteur ; Yasuko KANBAYASHI, Auteur ; Suyen KARKI, Auteur ; Hans M. KOOT, Auteur ; Michael C. LAMBERT, Auteur ; Patrick LEUNG, Auteur ; Dorcas N. MAGAI, Auteur ; Alfio MAGGIOLINI, Auteur ; Christa Winkler METZKE, Auteur ; Asghar MINAEI, Auteur ; Marina MONZANI DA ROCHA, Auteur ; Paulo A. S. MOREIRA, Auteur ; Mesfin S. MULATU, Auteur ; Torunn Stene NØVIK, Auteur ; Kyung Ja OH, Auteur ; Djaouida PETOT, Auteur ; Jean-Michel PETOT, Auteur ; Cecilia PISA, Auteur ; Rolando POMALIMA, Auteur ; Alexandra ROUSSOS, Auteur ; Vlasta RUDAN, Auteur ; Michael G. SAWYER, Auteur ; Mimoza SHAHINI, Auteur ; Zeynep SIMSEK, Auteur ; Hans-Christoph STEINHAUSEN, Auteur ; Frank C. VERHULST, Auteur ; Sheila WEINTRAUB, Auteur ; Bahr WEISS, Auteur ; Tomasz WOLANCZYK, Auteur ; Eugene Yuqing ZHANG, Auteur ; Nelly ZILBER, Auteur ; Rita ÅOEUKAUSKIENÄ–, Auteur . - p.1297-1307. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 63-11 (November 2022) . - p.1297-1307 Mots-clés : Child  Adolescent  Humans  Individuality  Parents/psychology  Self Report  Individual differences  Youth Self-Report  multicultural  psychopathology  strengths Index. décimale : PER Périodiques Résumé : BACKGROUND: Clinicians increasingly serve youths from societal/cultural backgrounds different from their own. This raises questions about how to interpret what such youths report. Rescorla et al. (2019, European Child & Adolescent Psychiatry, 28, 1107) found that much more variance in 72,493 parents' ratings of their offspring's mental health problems was accounted for by individual differences than by societal or cultural differences. Although parents' reports are essential for clinical assessment of their offspring, they reflect parents' perceptions of the offspring. Consequently, clinical assessment also requires self-reports from the offspring themselves. To test effects of individual differences, society, and culture on youths' self-ratings of their problems and strengths, we analyzed Youth Self-Report (YSR) scores for 39,849 11-17 year olds in 38 societies. METHODS: Indigenous researchers obtained YSR self-ratings from population samples of youths in 38 societies representing 10 culture cluster identified in the Global Leadership and Organizational Behavioral Effectiveness study. Hierarchical linear modeling of scores on 17 problem scales and one strengths scale estimated the percent of variance accounted for by individual differences (including measurement error), society, and culture cluster. ANOVAs tested age and gender effects. RESULTS: Averaged across the 17 problem scales, individual differences accounted for 92.5% of variance, societal differences 6.0%, and cultural differences 1.5%. For strengths, individual differences accounted for 83.4% of variance, societal differences 10.1%, and cultural differences 6.5%. Age and gender had very small effects. CONCLUSIONS: Like parents' ratings, youths' self-ratings of problems were affected much more by individual differences than societal/cultural differences. Most variance in self-rated strengths also reflected individual differences, but societal/cultural effects were larger than for problems, suggesting greater influence of social desirability. The clinical significance of individual differences in youths' self-reports should thus not be minimized by societal/cultural differences, which-while important-can be taken into account with appropriate norms, as can gender and age differences. En ligne : http://dx.doi.org/10.1111/jcpp.13569 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=490

Exploring ‘The autisms’ at a cognitive level / Cathriona CANTIO in Autism Research, 9-12 (December 2016)  

Public ISBD [article]  inAutism Research > 9-12 (December 2016) . - p.1328-1339 Titre : Exploring ‘The autisms’ at a cognitive level Type de document : Texte imprimé et/ou numérique Auteurs : Cathriona CANTIO, Auteur ; Jens Richardt MØLLEGAARD JEPSEN, Auteur ; Gitte FALCHER MADSEN, Auteur ; Niels BILENBERG, Auteur ; Sarah J. WHITE, Auteur Article en page(s) : p.1328-1339 Langues : Anglais (eng) Mots-clés : autism spectrum disorders  cognition  theory of mind  executive function  local bias  fractionation  symptomatology  Behavior Index. décimale : PER Périodiques Résumé : The autism spectrum is characterized by genetic and behavioral heterogeneity. However, it is still unknown whether there is a universal pattern of cognitive impairment in autism spectrum disorder (ASD) and whether multiple cognitive impairments are needed to explain the full range of behavioral symptoms. This study aimed to determine whether three widely acknowledged cognitive abnormalities (Theory of Mind (ToM) impairment, Executive Function (EF) impairment, and the presence of a Local Processing Bias (LB)) are universal and fractionable in autism, and whether the relationship between cognition and behavior is dependent on the method of behavioral assessment. Thirty-one high-functioning children with ASD and thirty-seven children with neurotypical development (NTD), comparable in age, gender and Intelligence Quotient (IQ), completed several tasks tapping into ToM, EF, and LB, and autistic symptomatology was assessed through parental and teacher questionnaires, parental interview and direct observation. We found that ToM and EF deficits differentiated the groups and some ToM and EF tasks were related to each other. ToM and EF were together able to correctly classify more than three-quarters of the children into cases and controls, despite relating to none of the specific behavioral measures. Only a small subgroup of individuals displayed a LB, which was unrelated to ToM and EF, and did not aid diagnostic classification, most likely contributing to non-diagnostic symptoms in a subgroup. Despite the characteristic heterogeneity of the autism spectrum, it remains a possibility therefore that a single cognitive cause may underlie the range of diagnostic symptoms in all individuals with autism. En ligne : http://dx.doi.org/10.1002/aur.1630 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298 [article] Exploring ‘The autisms’ at a cognitive level [Texte imprimé et/ou numérique] / Cathriona CANTIO, Auteur ; Jens Richardt MØLLEGAARD JEPSEN, Auteur ; Gitte FALCHER MADSEN, Auteur ; Niels BILENBERG, Auteur ; Sarah J. WHITE, Auteur . - p.1328-1339. Langues : Anglais (eng) in Autism Research > 9-12 (December 2016) . - p.1328-1339 Mots-clés : autism spectrum disorders  cognition  theory of mind  executive function  local bias  fractionation  symptomatology  Behavior Index. décimale : PER Périodiques Résumé : The autism spectrum is characterized by genetic and behavioral heterogeneity. However, it is still unknown whether there is a universal pattern of cognitive impairment in autism spectrum disorder (ASD) and whether multiple cognitive impairments are needed to explain the full range of behavioral symptoms. This study aimed to determine whether three widely acknowledged cognitive abnormalities (Theory of Mind (ToM) impairment, Executive Function (EF) impairment, and the presence of a Local Processing Bias (LB)) are universal and fractionable in autism, and whether the relationship between cognition and behavior is dependent on the method of behavioral assessment. Thirty-one high-functioning children with ASD and thirty-seven children with neurotypical development (NTD), comparable in age, gender and Intelligence Quotient (IQ), completed several tasks tapping into ToM, EF, and LB, and autistic symptomatology was assessed through parental and teacher questionnaires, parental interview and direct observation. We found that ToM and EF deficits differentiated the groups and some ToM and EF tasks were related to each other. ToM and EF were together able to correctly classify more than three-quarters of the children into cases and controls, despite relating to none of the specific behavioral measures. Only a small subgroup of individuals displayed a LB, which was unrelated to ToM and EF, and did not aid diagnostic classification, most likely contributing to non-diagnostic symptoms in a subgroup. Despite the characteristic heterogeneity of the autism spectrum, it remains a possibility therefore that a single cognitive cause may underlie the range of diagnostic symptoms in all individuals with autism. En ligne : http://dx.doi.org/10.1002/aur.1630 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=298

Increased Prepulse Inhibition and Sensitization of the Startle Reflex in Autistic Children / Gitte Falcher MADSEN in Autism Research, 7-1 (February 2014)  

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International Comparisons of Behavioral and Emotional Problems in Preschool Children: Parents' Reports From 24 Societies / Leslie A. RESCORLA in Journal of Clinical Child & Adolescent Psychology, 40-3 (May-June 2011)  

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Normal P50 Gating in Children with Autism, Yet Attenuated P50 Amplitude in the Asperger Subcategory / Gitte Falcher MADSEN in Autism Research, 8-4 (August 2015)  

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Oxidative Stress in Adults with Autism Spectrum Disorder: A Case Control Study / M. THORSEN in Journal of Autism and Developmental Disorders, 52-1 (January 2022)  

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Prenatal Androgen Exposure and Traits of Autism Spectrum Disorder in the Offspring: Odense Child Cohort / Camilla V. B. PALM in Journal of Autism and Developmental Disorders, 53-3 (March 2023)  

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Testing the 8-Syndrome Structure of the Child Behavior Checklist in 30 Societies / Masha Y. IVANOVA in Journal of Clinical Child & Adolescent Psychology, 36-3 (July-September 2007)  

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Toward a cumulative science of vocal markers of autism: A cross-linguistic meta-analysis-based investigation of acoustic markers in American and Danish autistic children / Riccardo FUSAROLI in Autism Research, 15-4 (April 2022)  

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Vocal markers of autism: Assessing the generalizability of machine learning models / Astrid RYBNER in Autism Research, 15-6 (June 2022)  

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