An Exploratory Trial of Transdermal Nicotine for Aggression and Irritability in Adults with Autism Spectrum Disorder / A. S. LEWIS in Journal of Autism and Developmental Disorders, 48-8 (August 2018)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 48-8 (August 2018) . - p.2748-2757 Titre : An Exploratory Trial of Transdermal Nicotine for Aggression and Irritability in Adults with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : A. S. LEWIS, Auteur ; Gerrit I. VAN SCHALKWYK, Auteur ; M. O. LOPEZ, Auteur ; Fred R. VOLKMAR, Auteur ; M. R. PICCIOTTO, Auteur ; D. G. SUKHODOLSKY, Auteur Article en page(s) : p.2748-2757 Langues : Anglais (eng) Mots-clés : Adult  Aggression  Autism spectrum disorder  Irritability  Nicotine  Nicotinic acetylcholine receptor  Sleep Index. décimale : PER Périodiques Résumé : Nicotinic acetylcholine receptors (nAChRs), particularly the alpha7 nAChR, are implicated in the pathophysiology of both autism spectrum disorder (ASD) and aggressive behavior. We explored the feasibility, tolerability, and preliminary efficacy of targeting nAChRs using transdermal nicotine to reduce aggressive symptoms in adults with ASD. Eight subjects were randomized in a double-blind crossover trial of 7 mg transdermal nicotine or placebo, each for 1 week. All participants tolerated nicotine treatment well. Five subjects contributed data to the primary outcome, Aberrant Behavior Checklist-Irritability (ABC-I) subscale change from baseline, which was improved by nicotine compared to placebo. Sleep ratings were also improved by nicotine and correlated with ABC-I improvement. These findings support further investigation of nAChR agonists for aggression and sleep in ASD. En ligne : http://dx.doi.org/10.1007/s10803-018-3536-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=367 [article] An Exploratory Trial of Transdermal Nicotine for Aggression and Irritability in Adults with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / A. S. LEWIS, Auteur ; Gerrit I. VAN SCHALKWYK, Auteur ; M. O. LOPEZ, Auteur ; Fred R. VOLKMAR, Auteur ; M. R. PICCIOTTO, Auteur ; D. G. SUKHODOLSKY, Auteur . - p.2748-2757. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 48-8 (August 2018) . - p.2748-2757 Mots-clés : Adult  Aggression  Autism spectrum disorder  Irritability  Nicotine  Nicotinic acetylcholine receptor  Sleep Index. décimale : PER Périodiques Résumé : Nicotinic acetylcholine receptors (nAChRs), particularly the alpha7 nAChR, are implicated in the pathophysiology of both autism spectrum disorder (ASD) and aggressive behavior. We explored the feasibility, tolerability, and preliminary efficacy of targeting nAChRs using transdermal nicotine to reduce aggressive symptoms in adults with ASD. Eight subjects were randomized in a double-blind crossover trial of 7 mg transdermal nicotine or placebo, each for 1 week. All participants tolerated nicotine treatment well. Five subjects contributed data to the primary outcome, Aberrant Behavior Checklist-Irritability (ABC-I) subscale change from baseline, which was improved by nicotine compared to placebo. Sleep ratings were also improved by nicotine and correlated with ABC-I improvement. These findings support further investigation of nAChR agonists for aggression and sleep in ASD. En ligne : http://dx.doi.org/10.1007/s10803-018-3536-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=367

At the Intersection of Neurodiversity and Gender Diversity / Gerrit I. VAN SCHALKWYK in Journal of Autism and Developmental Disorders, 48-12 (December 2018)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 48-12 (December 2018) . - p.3973 Titre : At the Intersection of Neurodiversity and Gender Diversity Type de document : Texte imprimé et/ou numérique Auteurs : Gerrit I. VAN SCHALKWYK, Auteur Article en page(s) : p.3973 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-018-3735-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=371 [article] At the Intersection of Neurodiversity and Gender Diversity [Texte imprimé et/ou numérique] / Gerrit I. VAN SCHALKWYK, Auteur . - p.3973. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 48-12 (December 2018) . - p.3973 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-018-3735-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=371

Brief Report: Bullying and Anxiety in High-Functioning Adolescents with ASD / Gerrit I. VAN SCHALKWYK in Journal of Autism and Developmental Disorders, 48-5 (May 2018)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 48-5 (May 2018) . - p.1819-1824 Titre : Brief Report: Bullying and Anxiety in High-Functioning Adolescents with ASD Type de document : Texte imprimé et/ou numérique Auteurs : Gerrit I. VAN SCHALKWYK, Auteur ; I. C. SMITH, Auteur ; W. K. SILVERMAN, Auteur ; Fred R. VOLKMAR, Auteur Article en page(s) : p.1819-1824 Langues : Anglais (eng) Mots-clés : Anxiety  Autism spectrum disorder  Bullying  Postsecondary education Index. décimale : PER Périodiques Résumé : Youth with ASD are more likely to experience bullying than their typically developing peers. This risk has not been studied in youth with ASD transitioning to college. We examined the occurrence of bullying in 35 high functioning youth with ASD who were preparing to attend college. We also examined youth anxiety and ASD symptoms. Fifty-one percent of the sample reported being recent victims of bullying; 31% of parents reported their child was a victim of bullying. Parent report of bullying correlated significantly with ratings of youth social anxiety symptoms. These findings suggest that bullying is an issue of concern for higher functioning, older adolescents with ASD, and that their own reports may be particularly important in identifying its occurrence. En ligne : http://dx.doi.org/10.1007/s10803-017-3378-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=355 [article] Brief Report: Bullying and Anxiety in High-Functioning Adolescents with ASD [Texte imprimé et/ou numérique] / Gerrit I. VAN SCHALKWYK, Auteur ; I. C. SMITH, Auteur ; W. K. SILVERMAN, Auteur ; Fred R. VOLKMAR, Auteur . - p.1819-1824. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 48-5 (May 2018) . - p.1819-1824 Mots-clés : Anxiety  Autism spectrum disorder  Bullying  Postsecondary education Index. décimale : PER Périodiques Résumé : Youth with ASD are more likely to experience bullying than their typically developing peers. This risk has not been studied in youth with ASD transitioning to college. We examined the occurrence of bullying in 35 high functioning youth with ASD who were preparing to attend college. We also examined youth anxiety and ASD symptoms. Fifty-one percent of the sample reported being recent victims of bullying; 31% of parents reported their child was a victim of bullying. Parent report of bullying correlated significantly with ratings of youth social anxiety symptoms. These findings suggest that bullying is an issue of concern for higher functioning, older adolescents with ASD, and that their own reports may be particularly important in identifying its occurrence. En ligne : http://dx.doi.org/10.1007/s10803-017-3378-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=355

A Predictive Coding Account of Psychotic Symptoms in Autism Spectrum Disorder / Gerrit I. VAN SCHALKWYK in Journal of Autism and Developmental Disorders, 47-5 (May 2017)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 47-5 (May 2017) . - p.1323-1340 Titre : A Predictive Coding Account of Psychotic Symptoms in Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Gerrit I. VAN SCHALKWYK, Auteur ; Fred R. VOLKMAR, Auteur ; Philip R. CORLETT, Auteur Article en page(s) : p.1323-1340 Langues : Anglais (eng) Mots-clés : Predictive coding  ASD and psychosis  ASD and schizophrenia Index. décimale : PER Périodiques Résumé : The co-occurrence of psychotic and autism spectrum disorder (ASD) symptoms represents an important clinical challenge. Here we consider this problem in the context of a computational psychiatry approach that has been applied to both conditions—predictive coding. Some symptoms of schizophrenia have been explained in terms of a failure of top–down predictions or an enhanced weighting of bottom–up prediction errors. Likewise, autism has been explained in terms of similar perturbations. We suggest that this theoretical overlap may explain overlapping symptomatology. Experimental evidence highlights meaningful distinctions and consistencies between these disorders. We hypothesize individuals with ASD may experience some degree of delusions without the presence of any additional impairment, but that hallucinations are likely indicative of a distinct process. En ligne : http://dx.doi.org/10.1007/s10803-017-3065-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=305 [article] A Predictive Coding Account of Psychotic Symptoms in Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Gerrit I. VAN SCHALKWYK, Auteur ; Fred R. VOLKMAR, Auteur ; Philip R. CORLETT, Auteur . - p.1323-1340. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 47-5 (May 2017) . - p.1323-1340 Mots-clés : Predictive coding  ASD and psychosis  ASD and schizophrenia Index. décimale : PER Périodiques Résumé : The co-occurrence of psychotic and autism spectrum disorder (ASD) symptoms represents an important clinical challenge. Here we consider this problem in the context of a computational psychiatry approach that has been applied to both conditions—predictive coding. Some symptoms of schizophrenia have been explained in terms of a failure of top–down predictions or an enhanced weighting of bottom–up prediction errors. Likewise, autism has been explained in terms of similar perturbations. We suggest that this theoretical overlap may explain overlapping symptomatology. Experimental evidence highlights meaningful distinctions and consistencies between these disorders. We hypothesize individuals with ASD may experience some degree of delusions without the presence of any additional impairment, but that hallucinations are likely indicative of a distinct process. En ligne : http://dx.doi.org/10.1007/s10803-017-3065-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=305

Qualitative Research in the Journal of Autism and Developmental Disorders / Gerrit I. VAN SCHALKWYK in Journal of Autism and Developmental Disorders, 50-7 (July 2020)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 50-7 (July 2020) . - p.2280-2282 Titre : Qualitative Research in the Journal of Autism and Developmental Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Gerrit I. VAN SCHALKWYK, Auteur ; Jeroen DEWINTER, Auteur Article en page(s) : p.2280-2282 Langues : Anglais (eng) Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-020-04466-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=426 [article] Qualitative Research in the Journal of Autism and Developmental Disorders [Texte imprimé et/ou numérique] / Gerrit I. VAN SCHALKWYK, Auteur ; Jeroen DEWINTER, Auteur . - p.2280-2282. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 50-7 (July 2020) . - p.2280-2282 Index. décimale : PER Périodiques En ligne : http://dx.doi.org/10.1007/s10803-020-04466-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=426

Reduction of Aggressive Episodes After Repeated Transdermal Nicotine Administration in a Hospitalized Adolescent with Autism Spectrum Disorder / Gerrit I. VAN SCHALKWYK in Journal of Autism and Developmental Disorders, 45-9 (September 2015)  

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Social Media Use, Friendship Quality, and the Moderating Role of Anxiety in Adolescents with Autism Spectrum Disorder / Gerrit I. VAN SCHALKWYK in Journal of Autism and Developmental Disorders, 47-9 (September 2017)  

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Systematic Review: Distribution of Age and Intervention Modalities in Therapeutic Clinical Trials for Autism Spectrum Disorder / Alan S. LEWIS in Journal of Autism and Developmental Disorders, 50-6 (June 2020)  

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Varieties of Misdiagnosis in ASD: An Illustrative Case Series / Gerrit I. VAN SCHALKWYK in Journal of Autism and Developmental Disorders, 45-4 (April 2015)  

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