An International Clinical Study of Ability and Disability in Autism Spectrum Disorder Using the WHO-ICF Framework / Soheil MAHDI in Journal of Autism and Developmental Disorders, 48-6 (June 2018)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 48-6 (June 2018) . - p.2148-2163 Titre : An International Clinical Study of Ability and Disability in Autism Spectrum Disorder Using the WHO-ICF Framework Type de document : texte imprimé Auteurs : Soheil MAHDI, Auteur ; Katja ALBERTOWSKI, Auteur ; Omar ALMODAYFER, Auteur ; Vaia ARSENOPOULOU, Auteur ; Sara CARUCCI, Auteur ; José Carlos DIAS, Auteur ; Mohammad KHALIL, Auteur ; A. KNUPPEL, Auteur ; Anika LANGMANN, Auteur ; Marlene Briciet LAURITSEN, Auteur ; Graccielle Rodrigues DA CUNHA, Auteur ; Tokio UCHIYAMA, Auteur ; Nicole WOLFF, Auteur ; Melissa SELB, Auteur ; Mats GRANLUND, Auteur ; Petrus J. DE VRIES, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Sven BÖLTE, Auteur Article en page(s) : p.2148-2163 Langues : Anglais (eng) Mots-clés : Asd  Assessment  Clinical study  Dsm  Functioning  Icd  Neurodevelopmental disorder Index. décimale : PER Périodiques Résumé : This is the fourth international preparatory study designed to develop International Classification of Functioning, Disability and Health (ICF, and Children and Youth version, ICF-CY) Core Sets for Autism Spectrum Disorder (ASD). Examine functioning of individuals diagnosed with ASD as documented by the ICF-CY in a variety of clinical settings. A cross-sectional study was conducted, involving 11 units from 10 countries. Clinical investigators assessed functioning of 122 individuals with ASD using the ICF-CY checklist. In total, 139 ICF-CY categories were identified: 64 activities and participation, 40 body functions and 35 environmental factors. The study results reinforce the heterogeneity of ASD, as evidenced by the many functional and contextual domains impacting on ASD from a clinical perspective. En ligne : http://dx.doi.org/10.1007/s10803-018-3482-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=362 [article] An International Clinical Study of Ability and Disability in Autism Spectrum Disorder Using the WHO-ICF Framework [texte imprimé] / Soheil MAHDI, Auteur ; Katja ALBERTOWSKI, Auteur ; Omar ALMODAYFER, Auteur ; Vaia ARSENOPOULOU, Auteur ; Sara CARUCCI, Auteur ; José Carlos DIAS, Auteur ; Mohammad KHALIL, Auteur ; A. KNUPPEL, Auteur ; Anika LANGMANN, Auteur ; Marlene Briciet LAURITSEN, Auteur ; Graccielle Rodrigues DA CUNHA, Auteur ; Tokio UCHIYAMA, Auteur ; Nicole WOLFF, Auteur ; Melissa SELB, Auteur ; Mats GRANLUND, Auteur ; Petrus J. DE VRIES, Auteur ; Lonnie ZWAIGENBAUM, Auteur ; Sven BÖLTE, Auteur . - p.2148-2163. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 48-6 (June 2018) . - p.2148-2163 Mots-clés : Asd  Assessment  Clinical study  Dsm  Functioning  Icd  Neurodevelopmental disorder Index. décimale : PER Périodiques Résumé : This is the fourth international preparatory study designed to develop International Classification of Functioning, Disability and Health (ICF, and Children and Youth version, ICF-CY) Core Sets for Autism Spectrum Disorder (ASD). Examine functioning of individuals diagnosed with ASD as documented by the ICF-CY in a variety of clinical settings. A cross-sectional study was conducted, involving 11 units from 10 countries. Clinical investigators assessed functioning of 122 individuals with ASD using the ICF-CY checklist. In total, 139 ICF-CY categories were identified: 64 activities and participation, 40 body functions and 35 environmental factors. The study results reinforce the heterogeneity of ASD, as evidenced by the many functional and contextual domains impacting on ASD from a clinical perspective. En ligne : http://dx.doi.org/10.1007/s10803-018-3482-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=362

Health Services Use and Costs in Individuals with Autism Spectrum Disorder in Germany: Results from a Survey in ASD Outpatient Clinics / J. HOFER in Journal of Autism and Developmental Disorders, 52-2 (February 2022)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 52-2 (February 2022) . - p.540-552 Titre : Health Services Use and Costs in Individuals with Autism Spectrum Disorder in Germany: Results from a Survey in ASD Outpatient Clinics Type de document : texte imprimé Auteurs : J. HOFER, Auteur ; Falk HOFFMANN, Auteur ; Michael DÖRKS, Auteur ; Inge KAMP-BECKER, Auteur ; Charlotte KÃœPPER, Auteur ; Luise POUSTKA, Auteur ; Stefan ROEPKE, Auteur ; Veit ROESSNER, Auteur ; Sanna STROTH, Auteur ; Nicole WOLFF, Auteur ; Christian J. BACHMANN, Auteur Article en page(s) : p.540-552 Langues : Anglais (eng) Mots-clés : Ambulatory Care Facilities  Autism Spectrum Disorder/epidemiology/therapy  Female  Germany/epidemiology  Health Care Costs  Humans  Male  Mental Health Services  Adolescents  Adults  Children  Costs  Germany  Health services Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASD) are associated with high services use, but European data on costs are scarce. Utilisation and annual costs of 385 individuals with ASD (aged 4-67 years; 18.2% females; 37.4% IQ < 85) from German outpatient clinics were assessed. Average annual costs per person were 3287 EUR, with psychiatric inpatient care (19.8%), pharmacotherapy (11.1%), and occupational therapy (11.1%) being the largest cost components. Females incurred higher costs than males (4864 EUR vs. 2936 EUR). In a regression model, female sex (Cost Ratio: 1.65), lower IQ (1.90), and Asperger syndrome (1.54) were associated with higher costs. In conclusion, ASD-related health costs are comparable to those of schizophrenia, thus underlining its public health relevance. Higher costs in females demand further research. En ligne : http://dx.doi.org/10.1007/s10803-021-04955-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=455 [article] Health Services Use and Costs in Individuals with Autism Spectrum Disorder in Germany: Results from a Survey in ASD Outpatient Clinics [texte imprimé] / J. HOFER, Auteur ; Falk HOFFMANN, Auteur ; Michael DÖRKS, Auteur ; Inge KAMP-BECKER, Auteur ; Charlotte KÃœPPER, Auteur ; Luise POUSTKA, Auteur ; Stefan ROEPKE, Auteur ; Veit ROESSNER, Auteur ; Sanna STROTH, Auteur ; Nicole WOLFF, Auteur ; Christian J. BACHMANN, Auteur . - p.540-552. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 52-2 (February 2022) . - p.540-552 Mots-clés : Ambulatory Care Facilities  Autism Spectrum Disorder/epidemiology/therapy  Female  Germany/epidemiology  Health Care Costs  Humans  Male  Mental Health Services  Adolescents  Adults  Children  Costs  Germany  Health services Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASD) are associated with high services use, but European data on costs are scarce. Utilisation and annual costs of 385 individuals with ASD (aged 4-67 years; 18.2% females; 37.4% IQ < 85) from German outpatient clinics were assessed. Average annual costs per person were 3287 EUR, with psychiatric inpatient care (19.8%), pharmacotherapy (11.1%), and occupational therapy (11.1%) being the largest cost components. Females incurred higher costs than males (4864 EUR vs. 2936 EUR). In a regression model, female sex (Cost Ratio: 1.65), lower IQ (1.90), and Asperger syndrome (1.54) were associated with higher costs. In conclusion, ASD-related health costs are comparable to those of schizophrenia, thus underlining its public health relevance. Higher costs in females demand further research. En ligne : http://dx.doi.org/10.1007/s10803-021-04955-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=455

How Do Adults with Autism Spectrum Disorder Participate in the Labor Market? A German Multi-center Survey / Tolou MASLAHATI in Journal of Autism and Developmental Disorders, 52-3 (March 2022)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 52-3 (March 2022) . - p.1066-1076 Titre : How Do Adults with Autism Spectrum Disorder Participate in the Labor Market? A German Multi-center Survey Type de document : texte imprimé Auteurs : Tolou MASLAHATI, Auteur ; Christian J. BACHMANN, Auteur ; J. HOFER, Auteur ; Charlotte KÃœPPER, Auteur ; Sanna STROTH, Auteur ; Nicole WOLFF, Auteur ; Luise POUSTKA, Auteur ; Veit ROESSNER, Auteur ; Inge KAMP-BECKER, Auteur ; Falk HOFFMANN, Auteur ; Stefan ROEPKE, Auteur Article en page(s) : p.1066-1076 Langues : Anglais (eng) Mots-clés : Adult  Autism Spectrum Disorder/epidemiology  Cross-Sectional Studies  Employment  Germany  Humans  Occupations  Surveys and Questionnaires  Autism  Autism Spectrum Disorder  Education  Labor Market Index. décimale : PER Périodiques Résumé : International studies show disadvantages for adults with autism spectrum disorder (ASD) in the labor market. Data about their participation in the German labor market are scarce. The aim of this study was to examine the integration of adults with ASD in the German labor market in terms of education, employment and type of occupation by means of a cross-sectional-study, using a postal questionnaire. Findings show above average levels of education for adults with ASD compared to the general population of Germany and simultaneously, below average rates of employment and high rates of financial dependency. That indicates a poor integration of adults with ASD in the German labor market and emphasizes the need for vocational support policies for adults with ASD. En ligne : http://dx.doi.org/10.1007/s10803-021-05008-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=455 [article] How Do Adults with Autism Spectrum Disorder Participate in the Labor Market? A German Multi-center Survey [texte imprimé] / Tolou MASLAHATI, Auteur ; Christian J. BACHMANN, Auteur ; J. HOFER, Auteur ; Charlotte KÃœPPER, Auteur ; Sanna STROTH, Auteur ; Nicole WOLFF, Auteur ; Luise POUSTKA, Auteur ; Veit ROESSNER, Auteur ; Inge KAMP-BECKER, Auteur ; Falk HOFFMANN, Auteur ; Stefan ROEPKE, Auteur . - p.1066-1076. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 52-3 (March 2022) . - p.1066-1076 Mots-clés : Adult  Autism Spectrum Disorder/epidemiology  Cross-Sectional Studies  Employment  Germany  Humans  Occupations  Surveys and Questionnaires  Autism  Autism Spectrum Disorder  Education  Labor Market Index. décimale : PER Périodiques Résumé : International studies show disadvantages for adults with autism spectrum disorder (ASD) in the labor market. Data about their participation in the German labor market are scarce. The aim of this study was to examine the integration of adults with ASD in the German labor market in terms of education, employment and type of occupation by means of a cross-sectional-study, using a postal questionnaire. Findings show above average levels of education for adults with ASD compared to the general population of Germany and simultaneously, below average rates of employment and high rates of financial dependency. That indicates a poor integration of adults with ASD in the German labor market and emphasizes the need for vocational support policies for adults with ASD. En ligne : http://dx.doi.org/10.1007/s10803-021-05008-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=455

Modulations of cognitive flexibility in obsessive compulsive disorder reflect dysfunctions of perceptual categorization / Nicole WOLFF in Journal of Child Psychology and Psychiatry, 58-8 (August 2017)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 58-8 (August 2017) . - p.939-949 Titre : Modulations of cognitive flexibility in obsessive compulsive disorder reflect dysfunctions of perceptual categorization Type de document : texte imprimé Auteurs : Nicole WOLFF, Auteur ; Judith BUSE, Auteur ; Jadwiga TOST, Auteur ; Veit ROESSNER, Auteur ; Christian BESTE, Auteur Article en page(s) : p.939-949 Langues : Anglais (eng) Mots-clés : Obsessive compulsive disorder  perception  neurophysiology  event-related potential Index. décimale : PER Périodiques Résumé : Background Despite cognitive inflexibility is trait like in obsessive compulsive disorder (OCD) patients and underlies clinical symptomatology, it is elusive at what stage of information processing deficits, leading to cognitive inflexibility, emerges. We hypothesize that inhibitory control mechanisms during early stimulus categorization and integration into a knowledge system underlie these deficits. Methods We examined N = 25 adolescent OCD patients and matched healthy controls (HC) in a paradigm manipulating the importance of the knowledge system to perform task switching. This was done using a paradigm in which task switches were signaled either by visual stimuli or by working memory processes. This was combined with event-related potential recordings and source localization. Results Obsessive compulsive disorder patients showed increased switch costs in the memory as compared with the cue-based block, while HC showed similar switch costs in both blocks. At the neurophysiological level, these changes in OCD were not reflected by the N2 and P3 reflecting response-associated processes but by the P1 reflecting inhibitory control during sensory categorization processes. Activation differences in the right inferior frontal gyrus and superior temporal gyrus are associated with the P1 effect. Conclusions Cognitive flexibility in adolescent OCD patients is strongly modulated by working memory load. Contrary to common sense, not response-associated processes, but inhibitory control mechanisms during early stimulus categorization processes are likely to underlie cognitive inflexibility in OCD. These processes are associated with right inferior frontal and superior temporal gyrus mechanisms. En ligne : http://dx.doi.org/10.1111/jcpp.12733 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=317 [article] Modulations of cognitive flexibility in obsessive compulsive disorder reflect dysfunctions of perceptual categorization [texte imprimé] / Nicole WOLFF, Auteur ; Judith BUSE, Auteur ; Jadwiga TOST, Auteur ; Veit ROESSNER, Auteur ; Christian BESTE, Auteur . - p.939-949. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 58-8 (August 2017) . - p.939-949 Mots-clés : Obsessive compulsive disorder  perception  neurophysiology  event-related potential Index. décimale : PER Périodiques Résumé : Background Despite cognitive inflexibility is trait like in obsessive compulsive disorder (OCD) patients and underlies clinical symptomatology, it is elusive at what stage of information processing deficits, leading to cognitive inflexibility, emerges. We hypothesize that inhibitory control mechanisms during early stimulus categorization and integration into a knowledge system underlie these deficits. Methods We examined N = 25 adolescent OCD patients and matched healthy controls (HC) in a paradigm manipulating the importance of the knowledge system to perform task switching. This was done using a paradigm in which task switches were signaled either by visual stimuli or by working memory processes. This was combined with event-related potential recordings and source localization. Results Obsessive compulsive disorder patients showed increased switch costs in the memory as compared with the cue-based block, while HC showed similar switch costs in both blocks. At the neurophysiological level, these changes in OCD were not reflected by the N2 and P3 reflecting response-associated processes but by the P1 reflecting inhibitory control during sensory categorization processes. Activation differences in the right inferior frontal gyrus and superior temporal gyrus are associated with the P1 effect. Conclusions Cognitive flexibility in adolescent OCD patients is strongly modulated by working memory load. Contrary to common sense, not response-associated processes, but inhibitory control mechanisms during early stimulus categorization processes are likely to underlie cognitive inflexibility in OCD. These processes are associated with right inferior frontal and superior temporal gyrus mechanisms. En ligne : http://dx.doi.org/10.1111/jcpp.12733 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=317

Phenotypic differences between female and male individuals with suspicion of autism spectrum disorder / Sanna STROTH in Molecular Autism, 13 (2022)  

Public ISBD [article]  inMolecular Autism > 13 (2022) . - 11 p. Titre : Phenotypic differences between female and male individuals with suspicion of autism spectrum disorder Type de document : texte imprimé Auteurs : Sanna STROTH, Auteur ; Johannes TAUSCHER, Auteur ; Nicole WOLFF, Auteur ; Charlotte KÃœPPER, Auteur ; Luise POUSTKA, Auteur ; Stefan ROEPKE, Auteur ; Veit ROESSNER, Auteur ; Dominik HEIDER, Auteur ; Inge KAMP-BECKER, Auteur Article en page(s) : 11 p. Langues : Anglais (eng) Mots-clés : Affect  Autism Spectrum Disorder/diagnosis  Autistic Disorder  Female  Humans  Intellectual Disability/diagnosis  Male  Adi-r  Ados  Asd  Diagnostics  Female autism  Phenotype  Sex Index. décimale : PER Périodiques Résumé : BACKGROUND: Although autism spectrum disorder (ASD) is a common developmental disorder, our knowledge about a behavioral and neurobiological female phenotype is still scarce. As the conceptualization and understanding of ASD are mainly based on the investigation of male individuals, females with ASD may not be adequately identified by routine clinical diagnostics. The present machine learning approach aimed to identify diagnostic information from the Autism Diagnostic Observation Schedule (ADOS) that discriminates best between ASD and non-ASD in females and males. METHODS: Random forests (RF) were used to discover patterns of symptoms in diagnostic data from the ADOS (modules 3 and 4) in 1057 participants with ASD (18.1% female) and 1230 participants with non-ASD (17.9% % female). Predictive performances of reduced feature models were explored and compared between females and males without intellectual disabilities. RESULTS: Reduced feature models relied on considerably fewer features from the ADOS in females compared to males, while still yielding similar classification performance (e.g., sensitivity, specificity). LIMITATIONS: As in previous studies, the current sample of females with ASD is smaller than the male sample and thus, females may still be underrepresented, limiting the statistical power to detect small to moderate effects. CONCLUSION: Our results do not suggest the need for new or altered diagnostic algorithms for females with ASD. Although we identified some phenotypic differences between females and males, the existing diagnostic tools seem to sufficiently capture the core autistic features in both groups. En ligne : http://dx.doi.org/10.1186/s13229-022-00491-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=477 [article] Phenotypic differences between female and male individuals with suspicion of autism spectrum disorder [texte imprimé] / Sanna STROTH, Auteur ; Johannes TAUSCHER, Auteur ; Nicole WOLFF, Auteur ; Charlotte KÃœPPER, Auteur ; Luise POUSTKA, Auteur ; Stefan ROEPKE, Auteur ; Veit ROESSNER, Auteur ; Dominik HEIDER, Auteur ; Inge KAMP-BECKER, Auteur . - 11 p. Langues : Anglais (eng) in Molecular Autism > 13 (2022) . - 11 p. Mots-clés : Affect  Autism Spectrum Disorder/diagnosis  Autistic Disorder  Female  Humans  Intellectual Disability/diagnosis  Male  Adi-r  Ados  Asd  Diagnostics  Female autism  Phenotype  Sex Index. décimale : PER Périodiques Résumé : BACKGROUND: Although autism spectrum disorder (ASD) is a common developmental disorder, our knowledge about a behavioral and neurobiological female phenotype is still scarce. As the conceptualization and understanding of ASD are mainly based on the investigation of male individuals, females with ASD may not be adequately identified by routine clinical diagnostics. The present machine learning approach aimed to identify diagnostic information from the Autism Diagnostic Observation Schedule (ADOS) that discriminates best between ASD and non-ASD in females and males. METHODS: Random forests (RF) were used to discover patterns of symptoms in diagnostic data from the ADOS (modules 3 and 4) in 1057 participants with ASD (18.1% female) and 1230 participants with non-ASD (17.9% % female). Predictive performances of reduced feature models were explored and compared between females and males without intellectual disabilities. RESULTS: Reduced feature models relied on considerably fewer features from the ADOS in females compared to males, while still yielding similar classification performance (e.g., sensitivity, specificity). LIMITATIONS: As in previous studies, the current sample of females with ASD is smaller than the male sample and thus, females may still be underrepresented, limiting the statistical power to detect small to moderate effects. CONCLUSION: Our results do not suggest the need for new or altered diagnostic algorithms for females with ASD. Although we identified some phenotypic differences between females and males, the existing diagnostic tools seem to sufficiently capture the core autistic features in both groups. En ligne : http://dx.doi.org/10.1186/s13229-022-00491-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=477

Using machine learning to improve diagnostic assessment of ASD in the light of specific differential and co-occurring diagnoses / Martin SCHULTE-RUTHER in Journal of Child Psychology and Psychiatry, 64-1 (January 2023)  

Permalink

When repetitive mental sets increase cognitive flexibility in adolescent obsessive–compulsive disorder / Nicole WOLFF in Journal of Child Psychology and Psychiatry, 59-9 (September 2018)  

Permalink

Willingness to try and lifetime use of complementary and alternative medicine in children and adolescents with autism spectrum disorder in Germany: A survey of parents / J. HOFER in Autism, 23-7 (October 2019)  

Permalink

---

1 (1 - 8 / 8) Par page : 25 50 100 200