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Résultat de la recherche
4 recherche sur le mot-clé 'Intellectual Disability/diagnosis'




Assessment of Autism Spectrum Disorder in Deaf Adults with Intellectual Disability: Feasibility and Psychometric Properties of an Adapted Version of the Autism Diagnostic Observation Schedule (ADOS-2) / D. HOLZINGER in Journal of Autism and Developmental Disorders, 52-7 (July 2022)
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Titre : Assessment of Autism Spectrum Disorder in Deaf Adults with Intellectual Disability: Feasibility and Psychometric Properties of an Adapted Version of the Autism Diagnostic Observation Schedule (ADOS-2) Type de document : Texte imprimé et/ou numérique Auteurs : D. HOLZINGER, Auteur ; C. WEBER, Auteur ; Sven BÖLTE, Auteur ; J. FELLINGER, Auteur ; J. HOFER, Auteur Article en page(s) : p.3214-3227 Langues : Anglais (eng) Mots-clés : Adult Autism Spectrum Disorder/diagnosis Autistic Disorder/diagnosis Feasibility Studies Humans Intellectual Disability/diagnosis Psychometrics Reproducibility of Results Ados-2 Autism spectrum disorder Deaf Diagnosis Intellectual disability Reliability Sensory impairment Index. décimale : PER Périodiques Résumé : This study describes the adaptation of the autism diagnostic observation schedule (ADOS-2) to assess autism spectrum disorder (ASD) in adults with intellectual disability (ID) and hearing loss who communicate primarily visually. This adapted ADOS-2 was applied to residents of specialized therapeutic living communities (n=56). The internal consistency of the adapted ADOS-2 was excellent for the Social Affect of modules 2 and 3 and acceptable for Restricted and Repetitive Behaviors subscale of module 2, but poor for module 3. Interrater reliability was comparable to standard ADOS-2 modules 1-3. Results suggest that autism symptoms of deaf adults with ID can be reliably identified by an adapted ADOS-2, provided adequate expertise in deafness, ID, ASD and proficiency in signed language by the administrator. En ligne : http://dx.doi.org/10.1007/s10803-021-05203-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=477
in Journal of Autism and Developmental Disorders > 52-7 (July 2022) . - p.3214-3227[article] Assessment of Autism Spectrum Disorder in Deaf Adults with Intellectual Disability: Feasibility and Psychometric Properties of an Adapted Version of the Autism Diagnostic Observation Schedule (ADOS-2) [Texte imprimé et/ou numérique] / D. HOLZINGER, Auteur ; C. WEBER, Auteur ; Sven BÖLTE, Auteur ; J. FELLINGER, Auteur ; J. HOFER, Auteur . - p.3214-3227.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 52-7 (July 2022) . - p.3214-3227
Mots-clés : Adult Autism Spectrum Disorder/diagnosis Autistic Disorder/diagnosis Feasibility Studies Humans Intellectual Disability/diagnosis Psychometrics Reproducibility of Results Ados-2 Autism spectrum disorder Deaf Diagnosis Intellectual disability Reliability Sensory impairment Index. décimale : PER Périodiques Résumé : This study describes the adaptation of the autism diagnostic observation schedule (ADOS-2) to assess autism spectrum disorder (ASD) in adults with intellectual disability (ID) and hearing loss who communicate primarily visually. This adapted ADOS-2 was applied to residents of specialized therapeutic living communities (n=56). The internal consistency of the adapted ADOS-2 was excellent for the Social Affect of modules 2 and 3 and acceptable for Restricted and Repetitive Behaviors subscale of module 2, but poor for module 3. Interrater reliability was comparable to standard ADOS-2 modules 1-3. Results suggest that autism symptoms of deaf adults with ID can be reliably identified by an adapted ADOS-2, provided adequate expertise in deafness, ID, ASD and proficiency in signed language by the administrator. En ligne : http://dx.doi.org/10.1007/s10803-021-05203-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=477 Self-Determination in Autistic Transition-Aged Youth without Intellectual Disability / Brianne TOMASZEWSKI in Journal of Autism and Developmental Disorders, 52-9 (September 2022)
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Titre : Self-Determination in Autistic Transition-Aged Youth without Intellectual Disability Type de document : Texte imprimé et/ou numérique Auteurs : Brianne TOMASZEWSKI, Auteur ; Laura G. KLINGER, Auteur ; Cara E. PUGLIESE, Auteur Article en page(s) : p.4067-4078 Langues : Anglais (eng) Mots-clés : Adolescent Adult Aged Autism Spectrum Disorder/diagnosis Autistic Disorder/diagnosis Child Communication Humans Intellectual Disability/diagnosis Personal Autonomy Adolescence Autism Executive function Self-determination Transition Young adult Index. décimale : PER Périodiques Résumé : Self-determination refers to an individual's capacity and opportunities to act as a causal agent in their own lives to make choices, decisions, and set goals. The current study examined self- and parent-reports of the AIR Self-Determination Scale in transition-aged autistic youth (Based on stakeholder preferences, we use identity-first(autistic) or neutral language (on the autism spectrum) (Bottema-Beutel in JAMA 3:18-29, 2020)). Autistic youth completed depression and executive function measures, and parents rated their child's social-communication and executive function difficulties. Despite differences between youth and parent reports, both youth and their parents reported lower self-determination skills (capacity) than opportunities to practice self-determined behaviors. Both depression and executive function skills were related to self-determination capacity, highlighting potential intervention targets for transition-aged youth to facilitate increased self-determination and potentially improved adult outcomes. En ligne : http://dx.doi.org/10.1007/s10803-021-05280-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=485
in Journal of Autism and Developmental Disorders > 52-9 (September 2022) . - p.4067-4078[article] Self-Determination in Autistic Transition-Aged Youth without Intellectual Disability [Texte imprimé et/ou numérique] / Brianne TOMASZEWSKI, Auteur ; Laura G. KLINGER, Auteur ; Cara E. PUGLIESE, Auteur . - p.4067-4078.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 52-9 (September 2022) . - p.4067-4078
Mots-clés : Adolescent Adult Aged Autism Spectrum Disorder/diagnosis Autistic Disorder/diagnosis Child Communication Humans Intellectual Disability/diagnosis Personal Autonomy Adolescence Autism Executive function Self-determination Transition Young adult Index. décimale : PER Périodiques Résumé : Self-determination refers to an individual's capacity and opportunities to act as a causal agent in their own lives to make choices, decisions, and set goals. The current study examined self- and parent-reports of the AIR Self-Determination Scale in transition-aged autistic youth (Based on stakeholder preferences, we use identity-first(autistic) or neutral language (on the autism spectrum) (Bottema-Beutel in JAMA 3:18-29, 2020)). Autistic youth completed depression and executive function measures, and parents rated their child's social-communication and executive function difficulties. Despite differences between youth and parent reports, both youth and their parents reported lower self-determination skills (capacity) than opportunities to practice self-determined behaviors. Both depression and executive function skills were related to self-determination capacity, highlighting potential intervention targets for transition-aged youth to facilitate increased self-determination and potentially improved adult outcomes. En ligne : http://dx.doi.org/10.1007/s10803-021-05280-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=485 Health-Related Quality of Life in Pediatric Patients with Syndromic Autism and their Caregivers / C. BOLBOCEAN in Journal of Autism and Developmental Disorders, 52-3 (March 2022)
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Titre : Health-Related Quality of Life in Pediatric Patients with Syndromic Autism and their Caregivers Type de document : Texte imprimé et/ou numérique Auteurs : C. BOLBOCEAN, Auteur ; F. N. ANDÚJAR, Auteur ; M. MCCORMACK, Auteur ; B. SUTER, Auteur ; J. L. HOLDER, Auteur Article en page(s) : p.1334-1345 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder/genetics Autistic Disorder Caregivers Child Chromosome Disorders/genetics Humans Intellectual Disability/diagnosis Quality of Life Autism spectrum disorder Beach center family quality of life Clinical research Diabetes Health related quality of life Idiopathic autism Intellectual disability Pediatric quality of life inventory Phelan-McDermid syndrome Rett syndrome SYNGAP1 related intellectual disability Index. décimale : PER Périodiques Résumé : Children with autism have a significantly lower quality of life compared with their neurotypical peers. While multiple studies have quantified the impact of autism on health-related quality of life (HRQoL) through standardized surveys such as the PedsQL, none have specifically investigated the impact of syndromic autism. Here we evaluate HRQoL in children diagnosed with three genetic disorders that strongly predispose to syndromic autism: Phelan-McDermid syndrome (PMD), Rett syndrome (RTT), and SYNGAP1-related intellectual disability (SYNGAP1-ID). We find the most severely impacted dimension is physical functioning. Strikingly, syndromic autism results in worse quality of life than other chronic disorders including idiopathic autism. This study demonstrates the utility of caregiver surveys in prioritizing phenotypes, which may be targeted as clinical endpoints for genetically defined ASDs. En ligne : http://dx.doi.org/10.1007/s10803-021-05030-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=455
in Journal of Autism and Developmental Disorders > 52-3 (March 2022) . - p.1334-1345[article] Health-Related Quality of Life in Pediatric Patients with Syndromic Autism and their Caregivers [Texte imprimé et/ou numérique] / C. BOLBOCEAN, Auteur ; F. N. ANDÚJAR, Auteur ; M. MCCORMACK, Auteur ; B. SUTER, Auteur ; J. L. HOLDER, Auteur . - p.1334-1345.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 52-3 (March 2022) . - p.1334-1345
Mots-clés : Autism Spectrum Disorder/genetics Autistic Disorder Caregivers Child Chromosome Disorders/genetics Humans Intellectual Disability/diagnosis Quality of Life Autism spectrum disorder Beach center family quality of life Clinical research Diabetes Health related quality of life Idiopathic autism Intellectual disability Pediatric quality of life inventory Phelan-McDermid syndrome Rett syndrome SYNGAP1 related intellectual disability Index. décimale : PER Périodiques Résumé : Children with autism have a significantly lower quality of life compared with their neurotypical peers. While multiple studies have quantified the impact of autism on health-related quality of life (HRQoL) through standardized surveys such as the PedsQL, none have specifically investigated the impact of syndromic autism. Here we evaluate HRQoL in children diagnosed with three genetic disorders that strongly predispose to syndromic autism: Phelan-McDermid syndrome (PMD), Rett syndrome (RTT), and SYNGAP1-related intellectual disability (SYNGAP1-ID). We find the most severely impacted dimension is physical functioning. Strikingly, syndromic autism results in worse quality of life than other chronic disorders including idiopathic autism. This study demonstrates the utility of caregiver surveys in prioritizing phenotypes, which may be targeted as clinical endpoints for genetically defined ASDs. En ligne : http://dx.doi.org/10.1007/s10803-021-05030-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=455 Phenotypic differences between female and male individuals with suspicion of autism spectrum disorder / Sanna STROTH in Molecular Autism, 13 (2022)
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Titre : Phenotypic differences between female and male individuals with suspicion of autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Sanna STROTH, Auteur ; Johannes TAUSCHER, Auteur ; Nicole WOLFF, Auteur ; Charlotte KÜPPER, Auteur ; Luise POUSTKA, Auteur ; Stefan ROEPKE, Auteur ; Veit ROESSNER, Auteur ; Dominik HEIDER, Auteur ; Inge KAMP-BECKER, Auteur Article en page(s) : 11 p. Langues : Anglais (eng) Mots-clés : Affect Autism Spectrum Disorder/diagnosis Autistic Disorder Female Humans Intellectual Disability/diagnosis Male Adi-r Ados Asd Diagnostics Female autism Phenotype Sex Index. décimale : PER Périodiques Résumé : BACKGROUND: Although autism spectrum disorder (ASD) is a common developmental disorder, our knowledge about a behavioral and neurobiological female phenotype is still scarce. As the conceptualization and understanding of ASD are mainly based on the investigation of male individuals, females with ASD may not be adequately identified by routine clinical diagnostics. The present machine learning approach aimed to identify diagnostic information from the Autism Diagnostic Observation Schedule (ADOS) that discriminates best between ASD and non-ASD in females and males. METHODS: Random forests (RF) were used to discover patterns of symptoms in diagnostic data from the ADOS (modules 3 and 4) in 1057 participants with ASD (18.1% female) and 1230 participants with non-ASD (17.9% % female). Predictive performances of reduced feature models were explored and compared between females and males without intellectual disabilities. RESULTS: Reduced feature models relied on considerably fewer features from the ADOS in females compared to males, while still yielding similar classification performance (e.g., sensitivity, specificity). LIMITATIONS: As in previous studies, the current sample of females with ASD is smaller than the male sample and thus, females may still be underrepresented, limiting the statistical power to detect small to moderate effects. CONCLUSION: Our results do not suggest the need for new or altered diagnostic algorithms for females with ASD. Although we identified some phenotypic differences between females and males, the existing diagnostic tools seem to sufficiently capture the core autistic features in both groups. En ligne : http://dx.doi.org/10.1186/s13229-022-00491-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=477
in Molecular Autism > 13 (2022) . - 11 p.[article] Phenotypic differences between female and male individuals with suspicion of autism spectrum disorder [Texte imprimé et/ou numérique] / Sanna STROTH, Auteur ; Johannes TAUSCHER, Auteur ; Nicole WOLFF, Auteur ; Charlotte KÜPPER, Auteur ; Luise POUSTKA, Auteur ; Stefan ROEPKE, Auteur ; Veit ROESSNER, Auteur ; Dominik HEIDER, Auteur ; Inge KAMP-BECKER, Auteur . - 11 p.
Langues : Anglais (eng)
in Molecular Autism > 13 (2022) . - 11 p.
Mots-clés : Affect Autism Spectrum Disorder/diagnosis Autistic Disorder Female Humans Intellectual Disability/diagnosis Male Adi-r Ados Asd Diagnostics Female autism Phenotype Sex Index. décimale : PER Périodiques Résumé : BACKGROUND: Although autism spectrum disorder (ASD) is a common developmental disorder, our knowledge about a behavioral and neurobiological female phenotype is still scarce. As the conceptualization and understanding of ASD are mainly based on the investigation of male individuals, females with ASD may not be adequately identified by routine clinical diagnostics. The present machine learning approach aimed to identify diagnostic information from the Autism Diagnostic Observation Schedule (ADOS) that discriminates best between ASD and non-ASD in females and males. METHODS: Random forests (RF) were used to discover patterns of symptoms in diagnostic data from the ADOS (modules 3 and 4) in 1057 participants with ASD (18.1% female) and 1230 participants with non-ASD (17.9% % female). Predictive performances of reduced feature models were explored and compared between females and males without intellectual disabilities. RESULTS: Reduced feature models relied on considerably fewer features from the ADOS in females compared to males, while still yielding similar classification performance (e.g., sensitivity, specificity). LIMITATIONS: As in previous studies, the current sample of females with ASD is smaller than the male sample and thus, females may still be underrepresented, limiting the statistical power to detect small to moderate effects. CONCLUSION: Our results do not suggest the need for new or altered diagnostic algorithms for females with ASD. Although we identified some phenotypic differences between females and males, the existing diagnostic tools seem to sufficiently capture the core autistic features in both groups. En ligne : http://dx.doi.org/10.1186/s13229-022-00491-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=477