7 recherche sur le mot-clé 'co-occurring conditions'

Co-occurring conditions and racial-ethnic disparities: Medicaid enrolled adults on the autism spectrum / W. SCHOTT in Autism Research, 15-1 (January 2022)  

Public ISBD [article]  inAutism Research > 15-1 (January 2022) . - p.70-85 Titre : Co-occurring conditions and racial-ethnic disparities: Medicaid enrolled adults on the autism spectrum Type de document : Texte imprimé et/ou numérique Auteurs : W. SCHOTT, Auteur ; S. TAO, Auteur ; L. SHEA, Auteur Article en page(s) : p.70-85 Langues : Anglais (eng) Mots-clés : Adult  Autism Spectrum Disorder/epidemiology  Autistic Disorder  Ethnicity  Humans  Medicaid  Minority Groups  United States/epidemiology  adults  autism  co-occurring conditions  racial disparities Index. décimale : PER Périodiques Résumé : Evidence suggests that autistic adults have higher odds of developing several co-occurring conditions, but less is known about disparities by race and ethnicity in this population. Using 2008-2012 Medicaid Analytic eXtract (MAX) data, we (i) identify the prevalence of co-occurring conditions among the population of autistic adult Medicaid beneficiaries compared to a matched sample of those without an autism spectrum disorder (ASD) diagnosis, (ii) conduct logistic regression to estimate odds ratios for these health conditions predicted by an autism diagnosis, and (iii) estimate odds of having these health conditions as predicted by racial/ethnic group among the autistic population only. Overall, autistic adults did not have higher prevalence of some major health conditions (cardiovascular conditions, stroke, cancer, cardiovascular disease), but they did have higher odds of others (nutrition conditions, epilepsy, disorders of the central nervous system). Analysis by racial/ethnic group, however, shows that Black, Hispanic, and Asian autistic beneficiaries had higher odds of diabetes, hospitalized cardiovascular diseases, and hypertension, among other conditions. Policymakers should be aware that racial disparities found in the general population persist in the autistic population and should work to implement systems and programs to improve screening and preventive care for minority autistic populations. LAY SUMMARY: Autistic adults may have several co-occurring physical and mental health conditions, which could differ by racial/ethnic group. We find that, compared to the general Medicaid population, autistic adult Medicaid beneficiaries have elevated odds of some health conditions, like epilepsy and nutrition conditions, as well as some psychiatric conditions, such as anxiety and attention disorders. We also find that many of the same health disparities by racial/ethnic group in the general population persist among the autistic adult Medicaid population. For example, Black, Hispanic, and Asian Medicaid autistic beneficiaries have higher odds of diabetes, and Black and Hispanic autistic beneficiaries have higher odds of obesity and nutrition conditions than white autistic beneficiaries. En ligne : http://dx.doi.org/10.1002/aur.2644 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450 [article] Co-occurring conditions and racial-ethnic disparities: Medicaid enrolled adults on the autism spectrum [Texte imprimé et/ou numérique] / W. SCHOTT, Auteur ; S. TAO, Auteur ; L. SHEA, Auteur . - p.70-85. Langues : Anglais (eng) in Autism Research > 15-1 (January 2022) . - p.70-85 Mots-clés : Adult  Autism Spectrum Disorder/epidemiology  Autistic Disorder  Ethnicity  Humans  Medicaid  Minority Groups  United States/epidemiology  adults  autism  co-occurring conditions  racial disparities Index. décimale : PER Périodiques Résumé : Evidence suggests that autistic adults have higher odds of developing several co-occurring conditions, but less is known about disparities by race and ethnicity in this population. Using 2008-2012 Medicaid Analytic eXtract (MAX) data, we (i) identify the prevalence of co-occurring conditions among the population of autistic adult Medicaid beneficiaries compared to a matched sample of those without an autism spectrum disorder (ASD) diagnosis, (ii) conduct logistic regression to estimate odds ratios for these health conditions predicted by an autism diagnosis, and (iii) estimate odds of having these health conditions as predicted by racial/ethnic group among the autistic population only. Overall, autistic adults did not have higher prevalence of some major health conditions (cardiovascular conditions, stroke, cancer, cardiovascular disease), but they did have higher odds of others (nutrition conditions, epilepsy, disorders of the central nervous system). Analysis by racial/ethnic group, however, shows that Black, Hispanic, and Asian autistic beneficiaries had higher odds of diabetes, hospitalized cardiovascular diseases, and hypertension, among other conditions. Policymakers should be aware that racial disparities found in the general population persist in the autistic population and should work to implement systems and programs to improve screening and preventive care for minority autistic populations. LAY SUMMARY: Autistic adults may have several co-occurring physical and mental health conditions, which could differ by racial/ethnic group. We find that, compared to the general Medicaid population, autistic adult Medicaid beneficiaries have elevated odds of some health conditions, like epilepsy and nutrition conditions, as well as some psychiatric conditions, such as anxiety and attention disorders. We also find that many of the same health disparities by racial/ethnic group in the general population persist among the autistic adult Medicaid population. For example, Black, Hispanic, and Asian Medicaid autistic beneficiaries have higher odds of diabetes, and Black and Hispanic autistic beneficiaries have higher odds of obesity and nutrition conditions than white autistic beneficiaries. En ligne : http://dx.doi.org/10.1002/aur.2644 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450

Classification of autism spectrum disorder from blood metabolites: Robustness to the presence of co-occurring conditions / Troy VARGASON in Research in Autism Spectrum Disorders, 77 (September 2020)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 77 (September 2020) . - 101644 Titre : Classification of autism spectrum disorder from blood metabolites: Robustness to the presence of co-occurring conditions Type de document : Texte imprimé et/ou numérique Auteurs : Troy VARGASON, Auteur ; Emily ROTH, Auteur ; Genevieve GRIVAS, Auteur ; Jennifer FERINA, Auteur ; Richard E. FRYE, Auteur ; Juergen HAHN, Auteur Article en page(s) : 101644 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Co-occurring conditions  Folate-dependent one-carbon metabolism  Transsulfuration  Multivariate analysis  Classification Index. décimale : PER Périodiques Résumé : Background Previous studies have found plasma measurements of metabolites from the folate-dependent one-carbon metabolism (FOCM) and transsulfuration (TS) pathways to be useful for differentiating individuals with autism spectrum disorder (ASD) from their typically developing peers. However, ASD is heterogeneous due to wide variation in the presence of co-occurring behavioral and medical conditions, and it is unknown how these conditions influence the ability to identify ASD based on FOCM/TS metabolites. Method This study employs a previously developed multivariate model that makes use of five FOCM/TS measurements (S-adenosylmethionine/S-adenosylhomocysteine, glutamylcysteine, glutathione disulfide, free cystine/free cysteine, and percent oxidized glutathione) to distinguish children with ASD from typically developing children. The model is used here to evaluate an independent cohort of individuals having ASD with diagnosed co-occurring conditions (age range 2–17 years old) and assess classifier performance in the presence/absence of these conditions. The four categories of co-occurring conditions considered were allergic disorders, gastrointestinal disorders, immune/metabolic disorders, and neurological disorders. All data were collected and retrospectively analyzed from previous clinical studies. Results The model was able to identify 124 of 131 participants with ASD (94.7 %) correctly regardless of co-occurring condition status. Model performance was generally not sensitive to the absence or presence of most co-occurring conditions, with the exceptions of ever/never having allergies or gastrointestinal symptoms, or currently (not) having any condition, all of which had minor impacts on model prediction accuracy. Conclusion The results of this exploratory study suggest that a FOCM/TS-based classifier for diagnosing ASD may potentially be robust to variations in co-occurring conditions and potentially applicable across ASD subtypes. Larger, more comprehensive follow-up studies with typically developing and/or developmentally delayed control groups are required to provide a more conclusive assessment of classifier robustness to co-occurring conditions. En ligne : https://doi.org/10.1016/j.rasd.2020.101644 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=432 [article] Classification of autism spectrum disorder from blood metabolites: Robustness to the presence of co-occurring conditions [Texte imprimé et/ou numérique] / Troy VARGASON, Auteur ; Emily ROTH, Auteur ; Genevieve GRIVAS, Auteur ; Jennifer FERINA, Auteur ; Richard E. FRYE, Auteur ; Juergen HAHN, Auteur . - 101644. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 77 (September 2020) . - 101644 Mots-clés : Autism spectrum disorder  Co-occurring conditions  Folate-dependent one-carbon metabolism  Transsulfuration  Multivariate analysis  Classification Index. décimale : PER Périodiques Résumé : Background Previous studies have found plasma measurements of metabolites from the folate-dependent one-carbon metabolism (FOCM) and transsulfuration (TS) pathways to be useful for differentiating individuals with autism spectrum disorder (ASD) from their typically developing peers. However, ASD is heterogeneous due to wide variation in the presence of co-occurring behavioral and medical conditions, and it is unknown how these conditions influence the ability to identify ASD based on FOCM/TS metabolites. Method This study employs a previously developed multivariate model that makes use of five FOCM/TS measurements (S-adenosylmethionine/S-adenosylhomocysteine, glutamylcysteine, glutathione disulfide, free cystine/free cysteine, and percent oxidized glutathione) to distinguish children with ASD from typically developing children. The model is used here to evaluate an independent cohort of individuals having ASD with diagnosed co-occurring conditions (age range 2–17 years old) and assess classifier performance in the presence/absence of these conditions. The four categories of co-occurring conditions considered were allergic disorders, gastrointestinal disorders, immune/metabolic disorders, and neurological disorders. All data were collected and retrospectively analyzed from previous clinical studies. Results The model was able to identify 124 of 131 participants with ASD (94.7 %) correctly regardless of co-occurring condition status. Model performance was generally not sensitive to the absence or presence of most co-occurring conditions, with the exceptions of ever/never having allergies or gastrointestinal symptoms, or currently (not) having any condition, all of which had minor impacts on model prediction accuracy. Conclusion The results of this exploratory study suggest that a FOCM/TS-based classifier for diagnosing ASD may potentially be robust to variations in co-occurring conditions and potentially applicable across ASD subtypes. Larger, more comprehensive follow-up studies with typically developing and/or developmentally delayed control groups are required to provide a more conclusive assessment of classifier robustness to co-occurring conditions. En ligne : https://doi.org/10.1016/j.rasd.2020.101644 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=432

Prevalence of Co-occurring Medical and Behavioral Conditions/Symptoms Among 4- and 8-Year-Old Children with Autism Spectrum Disorder in Selected Areas of the United States in 2010 / G. N. SOKE in Journal of Autism and Developmental Disorders, 48-8 (August 2018)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 48-8 (August 2018) . - p.2663-2676 Titre : Prevalence of Co-occurring Medical and Behavioral Conditions/Symptoms Among 4- and 8-Year-Old Children with Autism Spectrum Disorder in Selected Areas of the United States in 2010 Type de document : Texte imprimé et/ou numérique Auteurs : G. N. SOKE, Auteur ; M. J. MAENNER, Auteur ; D. CHRISTENSEN, Auteur ; M. KURZIUS-SPENCER, Auteur ; Laura A. SCHIEVE, Auteur Article en page(s) : p.2663-2676 Langues : Anglais (eng) Mots-clés : Autism  Autism spectrum disorder  Co-occurring conditions  Comorbid conditions  Prevalence Index. décimale : PER Périodiques Résumé : We compared the prevalence of various medical and behavioral co-occurring conditions/symptoms between 4- and 8-year-olds with autism spectrum disorder (ASD) from five sites in the Autism and Developmental Disabilities Monitoring Network during the 2010 survey year, accounting for sociodemographic differences. Over 95% of children had at least one co-occurring condition/symptom. Overall, the prevalence was higher in 8- than 4-year-olds for 67% of co-occurring conditions/symptoms examined. Further, our data suggested that co-occurring conditions/symptoms increased or decreased the age at which children were first evaluated for ASD. Similarly, among the 8-year-olds, the prevalence of most co-occurring conditions/symptoms was higher in children with a previous ASD diagnosis documented in their records. These findings are informative for understanding and screening co-occurring conditions/symptoms in ASD. En ligne : http://dx.doi.org/10.1007/s10803-018-3521-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=367 [article] Prevalence of Co-occurring Medical and Behavioral Conditions/Symptoms Among 4- and 8-Year-Old Children with Autism Spectrum Disorder in Selected Areas of the United States in 2010 [Texte imprimé et/ou numérique] / G. N. SOKE, Auteur ; M. J. MAENNER, Auteur ; D. CHRISTENSEN, Auteur ; M. KURZIUS-SPENCER, Auteur ; Laura A. SCHIEVE, Auteur . - p.2663-2676. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 48-8 (August 2018) . - p.2663-2676 Mots-clés : Autism  Autism spectrum disorder  Co-occurring conditions  Comorbid conditions  Prevalence Index. décimale : PER Périodiques Résumé : We compared the prevalence of various medical and behavioral co-occurring conditions/symptoms between 4- and 8-year-olds with autism spectrum disorder (ASD) from five sites in the Autism and Developmental Disabilities Monitoring Network during the 2010 survey year, accounting for sociodemographic differences. Over 95% of children had at least one co-occurring condition/symptom. Overall, the prevalence was higher in 8- than 4-year-olds for 67% of co-occurring conditions/symptoms examined. Further, our data suggested that co-occurring conditions/symptoms increased or decreased the age at which children were first evaluated for ASD. Similarly, among the 8-year-olds, the prevalence of most co-occurring conditions/symptoms was higher in children with a previous ASD diagnosis documented in their records. These findings are informative for understanding and screening co-occurring conditions/symptoms in ASD. En ligne : http://dx.doi.org/10.1007/s10803-018-3521-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=367

Sex differences in co-occurring conditions of children with autism spectrum disorders / Maria E. STACY in Autism, 18-8 (November 2014)  

Public ISBD [article]  inAutism > 18-8 (November 2014) . - p.965-974 Titre : Sex differences in co-occurring conditions of children with autism spectrum disorders Type de document : Texte imprimé et/ou numérique Auteurs : Maria E. STACY, Auteur ; Benjamin ZABLOTSKY, Auteur ; Heather A. YARGER, Auteur ; Andrew W. ZIMMERMAN, Auteur ; Barraw MAKIA, Auteur ; Li-Ching LEE, Auteur Article en page(s) : p.965-974 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  co-occurring conditions  sex Index. décimale : PER Périodiques Résumé : This study investigated differences in co-occurring diagnoses made in females compared to males with autism spectrum disorders in 913 children (746 males and 167 females) living in the United States with a current autism spectrum disorder diagnosis identified via caregiver-reported data from the National Survey of Children’s Health 2007. The results indicated that overall, females had significantly fewer reported autism spectrum disorder co-occurring conditions than males. Females, compared to males, with a current autism spectrum disorder diagnosis had lower rates of past learning disorder, current mild learning disorder, and past anxiety diagnoses. Females with a current autism spectrum disorder diagnosis were more likely than males to have been diagnosed with a speech problem in the past, while males with a current autism spectrum disorder diagnosis were more likely than females to have a current diagnosis of a mild learning disability and a past diagnosis of learning disability. In addition, males with a current autism spectrum disorder diagnosis were more likely than females to have two or more co-occurring diagnoses. These findings provide insight into trends in sex differences in autism spectrum disorder co-occurring conditions. En ligne : http://dx.doi.org/10.1177/1362361313505719 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=242 [article] Sex differences in co-occurring conditions of children with autism spectrum disorders [Texte imprimé et/ou numérique] / Maria E. STACY, Auteur ; Benjamin ZABLOTSKY, Auteur ; Heather A. YARGER, Auteur ; Andrew W. ZIMMERMAN, Auteur ; Barraw MAKIA, Auteur ; Li-Ching LEE, Auteur . - p.965-974. Langues : Anglais (eng) in Autism > 18-8 (November 2014) . - p.965-974 Mots-clés : Autism spectrum disorder  co-occurring conditions  sex Index. décimale : PER Périodiques Résumé : This study investigated differences in co-occurring diagnoses made in females compared to males with autism spectrum disorders in 913 children (746 males and 167 females) living in the United States with a current autism spectrum disorder diagnosis identified via caregiver-reported data from the National Survey of Children’s Health 2007. The results indicated that overall, females had significantly fewer reported autism spectrum disorder co-occurring conditions than males. Females, compared to males, with a current autism spectrum disorder diagnosis had lower rates of past learning disorder, current mild learning disorder, and past anxiety diagnoses. Females with a current autism spectrum disorder diagnosis were more likely than males to have been diagnosed with a speech problem in the past, while males with a current autism spectrum disorder diagnosis were more likely than females to have a current diagnosis of a mild learning disability and a past diagnosis of learning disability. In addition, males with a current autism spectrum disorder diagnosis were more likely than females to have two or more co-occurring diagnoses. These findings provide insight into trends in sex differences in autism spectrum disorder co-occurring conditions. En ligne : http://dx.doi.org/10.1177/1362361313505719 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=242

Brief report: A confirmatory factor analysis of the Child Behavior Checklist in a large sample of autistic youth / Laura DE LA ROCHE in Research in Autism Spectrum Disorders, 118 (October 2024)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 118 (October 2024) . - 102487 Titre : Brief report: A confirmatory factor analysis of the Child Behavior Checklist in a large sample of autistic youth Type de document : Texte imprimé et/ou numérique Auteurs : Laura DE LA ROCHE, Auteur ; Brianne DERBY, Auteur ; Molly PASCOE, Auteur ; Melissa SUSKO, Auteur ; Sabrina LUTCHMEAH, Auteur ; Jessica JONES, Auteur ; Stelios GEORGIADES, Auteur ; Rob NICOLSON, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Elizabeth KELLEY, Auteur Article en page(s) : 102487 Langues : Anglais (eng) Mots-clés : Autism  Child Behavior Checklist  Factor structure  Co-occurring conditions Index. décimale : PER Périodiques Résumé : Background Autistic youth often experience co-occurring psychiatric conditions. Checklist measures such as the Child Behavior Checklist (CBCL) can assist clinicians and researchers in assessing the symptom profiles of such conditions. Symptom profiles often overlap between autism and cooccurring psychiatric conditions (e.g., depression) in which the same symptoms occur in both. Previous research investigating the validity of the CBCL in autistic populations using factor structure has been mixed. Method Seven-hundred-and-fourteen autistic youth (293 females) aged 6-18 years (M = 11.25, SD = 3.29) participated. A confirmatory factor analysis of the 8-factor CBCL-6-18 was completed. Results Results suggest a poor model fit in autistic samples of the widely used eight-scale factor structure. Conclusions This model may not fit this sample due to the overlap of symptomatology autism has with other psychiatric condition profiles (e.g., communication and behaviors). Future research and implications, including an exploratory factor analysis on the CBCL/6-18 for autistic populations, are discussed. En ligne : https://doi.org/10.1016/j.rasd.2024.102487 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540 [article] Brief report: A confirmatory factor analysis of the Child Behavior Checklist in a large sample of autistic youth [Texte imprimé et/ou numérique] / Laura DE LA ROCHE, Auteur ; Brianne DERBY, Auteur ; Molly PASCOE, Auteur ; Melissa SUSKO, Auteur ; Sabrina LUTCHMEAH, Auteur ; Jessica JONES, Auteur ; Stelios GEORGIADES, Auteur ; Rob NICOLSON, Auteur ; Evdokia ANAGNOSTOU, Auteur ; Elizabeth KELLEY, Auteur . - 102487. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 118 (October 2024) . - 102487 Mots-clés : Autism  Child Behavior Checklist  Factor structure  Co-occurring conditions Index. décimale : PER Périodiques Résumé : Background Autistic youth often experience co-occurring psychiatric conditions. Checklist measures such as the Child Behavior Checklist (CBCL) can assist clinicians and researchers in assessing the symptom profiles of such conditions. Symptom profiles often overlap between autism and cooccurring psychiatric conditions (e.g., depression) in which the same symptoms occur in both. Previous research investigating the validity of the CBCL in autistic populations using factor structure has been mixed. Method Seven-hundred-and-fourteen autistic youth (293 females) aged 6-18 years (M = 11.25, SD = 3.29) participated. A confirmatory factor analysis of the 8-factor CBCL-6-18 was completed. Results Results suggest a poor model fit in autistic samples of the widely used eight-scale factor structure. Conclusions This model may not fit this sample due to the overlap of symptomatology autism has with other psychiatric condition profiles (e.g., communication and behaviors). Future research and implications, including an exploratory factor analysis on the CBCL/6-18 for autistic populations, are discussed. En ligne : https://doi.org/10.1016/j.rasd.2024.102487 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=540

Maternal risk factors vary between subpopulations of children with autism spectrum disorder / Genevieve GRIVAS in Autism Research, 15-11 (November 2022)  

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A Systematic Network of Autism Primary Care Services (SYNAPSE): A Model of Coproduction for the Management of Autism Spectrum Disorder / Xuejun KONG in Journal of Autism and Developmental Disorders, 50-5 (May 2020)  

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