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Résultat de la recherche
4 recherche sur le mot-clé 'neural synchrony'




Neural synchrony examined with magnetoencephalography (MEG) during eye gaze processing in autism spectrum disorders: preliminary findings / R. LAJINESS-O'NEILL in Journal of Neurodevelopmental Disorders, 6-1 (December 2014)
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[article]
Titre : Neural synchrony examined with magnetoencephalography (MEG) during eye gaze processing in autism spectrum disorders: preliminary findings Type de document : Texte imprimé et/ou numérique Auteurs : R. LAJINESS-O'NEILL, Auteur ; A. E. RICHARD, Auteur ; J. E. MORAN, Auteur ; A. OLSZEWSKI, Auteur ; L. PAWLUK, Auteur ; D. JACOBSON, Auteur ; A. MANSOUR, Auteur ; K. VOGT, Auteur ; L. A. ERDODI, Auteur ; A. M. MOORE, Auteur ; S. M. BOWYER, Auteur Article en page(s) : p.15 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Coherence Eye gaze Magnetoencephalography Neural synchrony Social cognition Index. décimale : PER Périodiques Résumé : BACKGROUND: Gaze processing deficits are a seminal, early, and enduring behavioral deficit in autism spectrum disorder (ASD); however, a comprehensive characterization of the neural processes mediating abnormal gaze processing in ASD has yet to be conducted. METHODS: This study investigated whole-brain patterns of neural synchrony during passive viewing of direct and averted eye gaze in ASD adolescents and young adults (M Age = 16.6) compared to neurotypicals (NT) (M Age = 17.5) while undergoing magnetoencephalography. Coherence between each pair of 54 brain regions within each of three frequency bands (low frequency (0 to 15 Hz), beta (15 to 30 Hz), and low gamma (30 to 45 Hz)) was calculated. RESULTS: Significantly higher coherence and synchronization in posterior brain regions (temporo-parietal-occipital) across all frequencies was evident in ASD, particularly within the low 0 to 15 Hz frequency range. Higher coherence in fronto-temporo-parietal regions was noted in NT. A significantly higher number of low frequency cross-hemispheric synchronous connections and a near absence of right intra-hemispheric coherence in the beta frequency band were noted in ASD. Significantly higher low frequency coherent activity in bilateral temporo-parieto-occipital cortical regions and higher gamma band coherence in right temporo-parieto-occipital brain regions during averted gaze was related to more severe symptomology as reported on the Autism Diagnostic Interview-Revised (ADI-R). CONCLUSIONS: The preliminary results suggest a pattern of aberrant connectivity that includes higher low frequency synchronization in posterior cortical regions, lack of long-range right hemispheric beta and gamma coherence, and decreased coherence in fronto-temporo-parietal regions necessary for orienting to shifts in eye gaze in ASD; a critical behavior essential for social communication. En ligne : http://dx.doi.org/10.1186/1866-1955-6-15 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=346
in Journal of Neurodevelopmental Disorders > 6-1 (December 2014) . - p.15[article] Neural synchrony examined with magnetoencephalography (MEG) during eye gaze processing in autism spectrum disorders: preliminary findings [Texte imprimé et/ou numérique] / R. LAJINESS-O'NEILL, Auteur ; A. E. RICHARD, Auteur ; J. E. MORAN, Auteur ; A. OLSZEWSKI, Auteur ; L. PAWLUK, Auteur ; D. JACOBSON, Auteur ; A. MANSOUR, Auteur ; K. VOGT, Auteur ; L. A. ERDODI, Auteur ; A. M. MOORE, Auteur ; S. M. BOWYER, Auteur . - p.15.
Langues : Anglais (eng)
in Journal of Neurodevelopmental Disorders > 6-1 (December 2014) . - p.15
Mots-clés : Autism spectrum disorder Coherence Eye gaze Magnetoencephalography Neural synchrony Social cognition Index. décimale : PER Périodiques Résumé : BACKGROUND: Gaze processing deficits are a seminal, early, and enduring behavioral deficit in autism spectrum disorder (ASD); however, a comprehensive characterization of the neural processes mediating abnormal gaze processing in ASD has yet to be conducted. METHODS: This study investigated whole-brain patterns of neural synchrony during passive viewing of direct and averted eye gaze in ASD adolescents and young adults (M Age = 16.6) compared to neurotypicals (NT) (M Age = 17.5) while undergoing magnetoencephalography. Coherence between each pair of 54 brain regions within each of three frequency bands (low frequency (0 to 15 Hz), beta (15 to 30 Hz), and low gamma (30 to 45 Hz)) was calculated. RESULTS: Significantly higher coherence and synchronization in posterior brain regions (temporo-parietal-occipital) across all frequencies was evident in ASD, particularly within the low 0 to 15 Hz frequency range. Higher coherence in fronto-temporo-parietal regions was noted in NT. A significantly higher number of low frequency cross-hemispheric synchronous connections and a near absence of right intra-hemispheric coherence in the beta frequency band were noted in ASD. Significantly higher low frequency coherent activity in bilateral temporo-parieto-occipital cortical regions and higher gamma band coherence in right temporo-parieto-occipital brain regions during averted gaze was related to more severe symptomology as reported on the Autism Diagnostic Interview-Revised (ADI-R). CONCLUSIONS: The preliminary results suggest a pattern of aberrant connectivity that includes higher low frequency synchronization in posterior cortical regions, lack of long-range right hemispheric beta and gamma coherence, and decreased coherence in fronto-temporo-parietal regions necessary for orienting to shifts in eye gaze in ASD; a critical behavior essential for social communication. En ligne : http://dx.doi.org/10.1186/1866-1955-6-15 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=346 Parent-child neural synchrony: a novel approach to elucidating dyadic correlates of preschool irritability / Laura E. QUIÑONES-CAMACHO in Journal of Child Psychology and Psychiatry, 61-11 (November 2020)
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Titre : Parent-child neural synchrony: a novel approach to elucidating dyadic correlates of preschool irritability Type de document : Texte imprimé et/ou numérique Auteurs : Laura E. QUIÑONES-CAMACHO, Auteur ; Frank A. FISHBURN, Auteur ; M. Catalina CAMACHO, Auteur ; Christina O. HLUTKOWSKY, Auteur ; Theodore J. HUPPERT, Auteur ; Lauren S. WAKSCHLAG, Auteur ; Susan B. PERLMAN, Auteur Article en page(s) : p.1213-1223 Langues : Anglais (eng) Mots-clés : Neural synchrony irritability parent-child synchrony prefrontal cortex recovery Index. décimale : PER Périodiques Résumé : BACKGROUND: Research to date has largely conceptualized irritability in terms of intraindividual differences. However, the role of interpersonal dyadic processes has received little consideration. Nevertheless, difficulties in how parent-child dyads synchronize during interactions may be an important correlate of irritably in early childhood. Innovations in developmentally sensitive neuroimaging methods now enable the use of measures of neural synchrony to quantify synchronous responses in parent-child dyads and can help clarify the neural underpinnings of these difficulties. We introduce the Disruptive Behavior Diagnostic Observation Schedule: Biological Synchrony (DB-DOS:BioSync) as a paradigm for exploring parent-child neural synchrony as a potential biological mechanism for interpersonal difficulties in preschool psychopathology. METHODS: Using functional near-infrared spectroscopy (fNIRS) 4- to 5-year-olds (N = 116) and their mothers completed the DB-DOS:BioSync while assessing neural synchrony during mild frustration and recovery. Child irritability was measured using a latent irritability factor that was calculated from four developmentally sensitive indicators. RESULTS: Both the mild frustration and the recovery contexts resulted in neural synchrony. However, less neural synchrony during the recovery context only was associated with more child irritability. CONCLUSIONS: Our results suggest that recovering after a frustrating period might be particularly challenging for children high in irritability and offer support for the use of the DB-DOS:BioSync task to elucidate interpersonal neural mechanisms of developmental psychopathology. En ligne : http://dx.doi.org/10.1111/jcpp.13165 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434
in Journal of Child Psychology and Psychiatry > 61-11 (November 2020) . - p.1213-1223[article] Parent-child neural synchrony: a novel approach to elucidating dyadic correlates of preschool irritability [Texte imprimé et/ou numérique] / Laura E. QUIÑONES-CAMACHO, Auteur ; Frank A. FISHBURN, Auteur ; M. Catalina CAMACHO, Auteur ; Christina O. HLUTKOWSKY, Auteur ; Theodore J. HUPPERT, Auteur ; Lauren S. WAKSCHLAG, Auteur ; Susan B. PERLMAN, Auteur . - p.1213-1223.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 61-11 (November 2020) . - p.1213-1223
Mots-clés : Neural synchrony irritability parent-child synchrony prefrontal cortex recovery Index. décimale : PER Périodiques Résumé : BACKGROUND: Research to date has largely conceptualized irritability in terms of intraindividual differences. However, the role of interpersonal dyadic processes has received little consideration. Nevertheless, difficulties in how parent-child dyads synchronize during interactions may be an important correlate of irritably in early childhood. Innovations in developmentally sensitive neuroimaging methods now enable the use of measures of neural synchrony to quantify synchronous responses in parent-child dyads and can help clarify the neural underpinnings of these difficulties. We introduce the Disruptive Behavior Diagnostic Observation Schedule: Biological Synchrony (DB-DOS:BioSync) as a paradigm for exploring parent-child neural synchrony as a potential biological mechanism for interpersonal difficulties in preschool psychopathology. METHODS: Using functional near-infrared spectroscopy (fNIRS) 4- to 5-year-olds (N = 116) and their mothers completed the DB-DOS:BioSync while assessing neural synchrony during mild frustration and recovery. Child irritability was measured using a latent irritability factor that was calculated from four developmentally sensitive indicators. RESULTS: Both the mild frustration and the recovery contexts resulted in neural synchrony. However, less neural synchrony during the recovery context only was associated with more child irritability. CONCLUSIONS: Our results suggest that recovering after a frustrating period might be particularly challenging for children high in irritability and offer support for the use of the DB-DOS:BioSync task to elucidate interpersonal neural mechanisms of developmental psychopathology. En ligne : http://dx.doi.org/10.1111/jcpp.13165 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434 Dysfunction in interpersonal neural synchronization as a mechanism for social impairment in autism spectrum disorder / Laura E. QUIÑONES-CAMACHO in Autism Research, 14-8 (August 2021)
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Titre : Dysfunction in interpersonal neural synchronization as a mechanism for social impairment in autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : Laura E. QUIÑONES-CAMACHO, Auteur ; F. A. FISHBURN, Auteur ; Katie BELARDI, Auteur ; D. L. WILLIAMS, Auteur ; T. J. HUPPERT, Auteur ; Susan B. PERLMAN, Auteur Article en page(s) : p.1585-1596 Langues : Anglais (eng) Mots-clés : Adult Autism Spectrum Disorder Brain Brain Mapping Humans Mentalization Spectroscopy, Near-Infrared Asd Tpj neural synchrony social communication impairment social deficits Index. décimale : PER Périodiques Résumé : Social deficits in autism spectrum disorder (ASD) have been linked to atypical activation of the mentalizing network. This work, however, has been limited by a focus on the brain activity of a single person during computerized social tasks rather than exploring brain activity during in vivo interactions. The current study assessed neural synchronization during a conversation as a mechanism for social impairment in adults with ASD (n = 24) and matched controls (n = 26). Functional near-infrared spectroscopy (fNIRS) data were collected from the prefrontal cortex (PFC) and tempoparietal junction (TPJ). Participants self-reported on their social communication and videos of the interaction were coded for utterances and conversational turns. As expected, controls showed more neural synchrony than participants with ASD in the TPJ. Also as expected, controls showed less social communication impairment than participants with ASD. However, participants with ASD did not have fewer utterances compared with control subjects. Overall, less neural synchrony in the TPJ was associated with higher social impairment and marginally fewer utterances. Our findings advance our understanding of social difficulties in ASD by linking them to decreased neural synchronization of the TPJ. LAY SUMMARY: The coordination of brain responses is important for efficient social interactions. The current study explored the coordination of brain responses in neurotypical adults and adults with ASD to investigate if difficulties in social interactions are related to difficulties coordinating brain responses in ASD. We found that participants with ASD had more difficulties coordinating brain responses during a conversation with an interacting partner. Additionally, we found that the level of coordination in brain responses was linked to problems with social communication. En ligne : http://dx.doi.org/10.1002/aur.2513 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=449
in Autism Research > 14-8 (August 2021) . - p.1585-1596[article] Dysfunction in interpersonal neural synchronization as a mechanism for social impairment in autism spectrum disorder [Texte imprimé et/ou numérique] / Laura E. QUIÑONES-CAMACHO, Auteur ; F. A. FISHBURN, Auteur ; Katie BELARDI, Auteur ; D. L. WILLIAMS, Auteur ; T. J. HUPPERT, Auteur ; Susan B. PERLMAN, Auteur . - p.1585-1596.
Langues : Anglais (eng)
in Autism Research > 14-8 (August 2021) . - p.1585-1596
Mots-clés : Adult Autism Spectrum Disorder Brain Brain Mapping Humans Mentalization Spectroscopy, Near-Infrared Asd Tpj neural synchrony social communication impairment social deficits Index. décimale : PER Périodiques Résumé : Social deficits in autism spectrum disorder (ASD) have been linked to atypical activation of the mentalizing network. This work, however, has been limited by a focus on the brain activity of a single person during computerized social tasks rather than exploring brain activity during in vivo interactions. The current study assessed neural synchronization during a conversation as a mechanism for social impairment in adults with ASD (n = 24) and matched controls (n = 26). Functional near-infrared spectroscopy (fNIRS) data were collected from the prefrontal cortex (PFC) and tempoparietal junction (TPJ). Participants self-reported on their social communication and videos of the interaction were coded for utterances and conversational turns. As expected, controls showed more neural synchrony than participants with ASD in the TPJ. Also as expected, controls showed less social communication impairment than participants with ASD. However, participants with ASD did not have fewer utterances compared with control subjects. Overall, less neural synchrony in the TPJ was associated with higher social impairment and marginally fewer utterances. Our findings advance our understanding of social difficulties in ASD by linking them to decreased neural synchronization of the TPJ. LAY SUMMARY: The coordination of brain responses is important for efficient social interactions. The current study explored the coordination of brain responses in neurotypical adults and adults with ASD to investigate if difficulties in social interactions are related to difficulties coordinating brain responses in ASD. We found that participants with ASD had more difficulties coordinating brain responses during a conversation with an interacting partner. Additionally, we found that the level of coordination in brain responses was linked to problems with social communication. En ligne : http://dx.doi.org/10.1002/aur.2513 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=449 Getting in synch: Unpacking the role of parent–child synchrony in the development of internalizing and externalizing behaviors / Laura E. QUIÑONES-CAMACHO in Development and Psychopathology, 34-5 (December 2022)
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Titre : Getting in synch: Unpacking the role of parent–child synchrony in the development of internalizing and externalizing behaviors Type de document : Texte imprimé et/ou numérique Auteurs : Laura E. QUIÑONES-CAMACHO, Auteur ; Caroline P. HOYNIAK, Auteur ; Lauren S. WAKSCHLAG, Auteur ; Susan B. PERLMAN, Auteur Article en page(s) : p.1901-1913 Langues : Anglais (eng) Mots-clés : externalizing internalizing neural synchrony parent–child synchrony prefrontal cortex (PFC) Index. décimale : PER Périodiques Résumé : While substantial research supports the role of parent “child interactions on the emergence of psychiatric symptoms, few studies have explored biological mechanisms for this association. The current study explored behavioral and neural parent “child synchronization during frustration and play as predictors of internalizing and externalizing behaviors across a span of 1.5 years. Parent “child dyads first came to the laboratory when the child was 4 “5 years old and completed the Disruptive Behavior Diagnostic Observation Schedule: Biological Synchrony (DB-DOS: BioSync) task while functional near-infrared spectroscopy (fNIRS) data were recorded. Parents reported on their child's internalizing and externalizing behaviors using the Child Behavior Checklist (CBCL) four times over 1.5 years. Latent growth curve (LGC) modeling was conducted to assess neural and behavioral synchrony as predictors of internalizing and externalizing trajectories. Consistent with previous investigations in this age range, on average, internalizing and externalizing behaviors decreased over the four time points. Parent “child neural synchrony during a period of play predicted rate of change in internalizing but not externalizing behaviors such that higher parent “child neural synchrony was associated with a more rapid decrease in internalizing behaviors. Our results suggest that a parent “child dyad's ability to coordinate neural activation during positive interactions might serve as a protective mechanism in the context of internalizing behaviors. En ligne : http://dx.doi.org/10.1017/S0954579421000468 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=492
in Development and Psychopathology > 34-5 (December 2022) . - p.1901-1913[article] Getting in synch: Unpacking the role of parent–child synchrony in the development of internalizing and externalizing behaviors [Texte imprimé et/ou numérique] / Laura E. QUIÑONES-CAMACHO, Auteur ; Caroline P. HOYNIAK, Auteur ; Lauren S. WAKSCHLAG, Auteur ; Susan B. PERLMAN, Auteur . - p.1901-1913.
Langues : Anglais (eng)
in Development and Psychopathology > 34-5 (December 2022) . - p.1901-1913
Mots-clés : externalizing internalizing neural synchrony parent–child synchrony prefrontal cortex (PFC) Index. décimale : PER Périodiques Résumé : While substantial research supports the role of parent “child interactions on the emergence of psychiatric symptoms, few studies have explored biological mechanisms for this association. The current study explored behavioral and neural parent “child synchronization during frustration and play as predictors of internalizing and externalizing behaviors across a span of 1.5 years. Parent “child dyads first came to the laboratory when the child was 4 “5 years old and completed the Disruptive Behavior Diagnostic Observation Schedule: Biological Synchrony (DB-DOS: BioSync) task while functional near-infrared spectroscopy (fNIRS) data were recorded. Parents reported on their child's internalizing and externalizing behaviors using the Child Behavior Checklist (CBCL) four times over 1.5 years. Latent growth curve (LGC) modeling was conducted to assess neural and behavioral synchrony as predictors of internalizing and externalizing trajectories. Consistent with previous investigations in this age range, on average, internalizing and externalizing behaviors decreased over the four time points. Parent “child neural synchrony during a period of play predicted rate of change in internalizing but not externalizing behaviors such that higher parent “child neural synchrony was associated with a more rapid decrease in internalizing behaviors. Our results suggest that a parent “child dyad's ability to coordinate neural activation during positive interactions might serve as a protective mechanism in the context of internalizing behaviors. En ligne : http://dx.doi.org/10.1017/S0954579421000468 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=492