4 recherche sur le mot-clé 'social function'

Associations between social cognition, skills, and function and subclinical negative and positive symptoms in 22q11.2 deletion syndrome / A. VANGKILDE in Journal of Neurodevelopmental Disorders, 8-1 (December 2016)  

Public ISBD [article]  inJournal of Neurodevelopmental Disorders > 8-1 (December 2016) . - p.42 Titre : Associations between social cognition, skills, and function and subclinical negative and positive symptoms in 22q11.2 deletion syndrome Type de document : Texte imprimé et/ou numérique Auteurs : A. VANGKILDE, Auteur ; Jens Richardt MØLLEGAARD JEPSEN, Auteur ; H. SCHMOCK, Auteur ; C. OLESEN, Auteur ; S. ARNARSDOTTIR, Auteur ; W. F. BAARE, Auteur ; K. J. PLESSEN, Auteur ; M. DIDRIKSEN, Auteur ; H. R. SIEBNER, Auteur ; T. WERGE, Auteur ; L. OLSEN, Auteur Article en page(s) : p.42 Langues : Anglais (eng) Mots-clés : 22q11 deletion syndrome  Emotional recognition task  Negative symptoms  Positive symptoms  Schizophrenia  Social cognition  Social function  Social skills  Theory of mind Index. décimale : PER Périodiques Résumé : BACKGROUND: Identification of the early signs of schizophrenia would be a major achievement for the early intervention and prevention strategies in psychiatry. Social impairments are defining features of schizophrenia. Impairments of individual layers of social competencies are frequently described in individuals with 22q11.2 deletion syndrome (22q11.2DS), who have high risk of schizophrenia. It is unclear whether and to what extent social impairments associate with subclinical negative and positive symptoms in 22q11.2DS, and which layer of social impairments are more correlated with schizophrenia-related symptoms. The aims of this study were to conduct a comprehensive investigation of social impairments at three different levels (function, skill, and cognition) and their interrelationship and to determine to what degree the social impairments correlate to subclinical levels of negative and positive symptoms, respectively, in a young cohort of 22q11.2DS not diagnosed with schizophrenia. METHODS: The level of social impairment was addressed using questionnaires and objective measures of social functioning (The Adaptive Behavior Assessment System), skills (Social Responsiveness Scale), and cognition (The Awareness of Social Inference Test and CANTAB Emotional Recognition Task), and the presence of subclinical symptoms of schizophrenia were evaluated using the Structured Interview for Prodromal Syndromes in a cross-sectional case-control study of 29 cases and 29 controls, aged 12 to 25 years. Association between social impairment and negative and positive symptoms levels was examined in cases only. RESULTS: Subjects with 22q11.2DS were highly impaired in social function, social skills, and social cognition (p En ligne : http://dx.doi.org/10.1186/s11689-016-9175-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=349 [article] Associations between social cognition, skills, and function and subclinical negative and positive symptoms in 22q11.2 deletion syndrome [Texte imprimé et/ou numérique] / A. VANGKILDE, Auteur ; Jens Richardt MØLLEGAARD JEPSEN, Auteur ; H. SCHMOCK, Auteur ; C. OLESEN, Auteur ; S. ARNARSDOTTIR, Auteur ; W. F. BAARE, Auteur ; K. J. PLESSEN, Auteur ; M. DIDRIKSEN, Auteur ; H. R. SIEBNER, Auteur ; T. WERGE, Auteur ; L. OLSEN, Auteur . - p.42. Langues : Anglais (eng) in Journal of Neurodevelopmental Disorders > 8-1 (December 2016) . - p.42 Mots-clés : 22q11 deletion syndrome  Emotional recognition task  Negative symptoms  Positive symptoms  Schizophrenia  Social cognition  Social function  Social skills  Theory of mind Index. décimale : PER Périodiques Résumé : BACKGROUND: Identification of the early signs of schizophrenia would be a major achievement for the early intervention and prevention strategies in psychiatry. Social impairments are defining features of schizophrenia. Impairments of individual layers of social competencies are frequently described in individuals with 22q11.2 deletion syndrome (22q11.2DS), who have high risk of schizophrenia. It is unclear whether and to what extent social impairments associate with subclinical negative and positive symptoms in 22q11.2DS, and which layer of social impairments are more correlated with schizophrenia-related symptoms. The aims of this study were to conduct a comprehensive investigation of social impairments at three different levels (function, skill, and cognition) and their interrelationship and to determine to what degree the social impairments correlate to subclinical levels of negative and positive symptoms, respectively, in a young cohort of 22q11.2DS not diagnosed with schizophrenia. METHODS: The level of social impairment was addressed using questionnaires and objective measures of social functioning (The Adaptive Behavior Assessment System), skills (Social Responsiveness Scale), and cognition (The Awareness of Social Inference Test and CANTAB Emotional Recognition Task), and the presence of subclinical symptoms of schizophrenia were evaluated using the Structured Interview for Prodromal Syndromes in a cross-sectional case-control study of 29 cases and 29 controls, aged 12 to 25 years. Association between social impairment and negative and positive symptoms levels was examined in cases only. RESULTS: Subjects with 22q11.2DS were highly impaired in social function, social skills, and social cognition (p En ligne : http://dx.doi.org/10.1186/s11689-016-9175-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=349

"Intolerance of uncertainty" mediates the relationship between social profile and anxiety in both Williams syndrome and autism / M. SOUTH in Autism Research, 14-9 (September 2021)  

Public ISBD [article]  inAutism Research > 14-9 (September 2021) . - p.1986-1995 Titre : "Intolerance of uncertainty" mediates the relationship between social profile and anxiety in both Williams syndrome and autism Type de document : Texte imprimé et/ou numérique Auteurs : M. SOUTH, Auteur ; M. HANLEY, Auteur ; K. NORMANSELL-MOSSA, Auteur ; N. C. C. RUSSELL, Auteur ; Thomas CAWTHORNE, Auteur ; D. M. RIBY, Auteur Article en page(s) : p.1986-1995 Langues : Anglais (eng) Mots-clés : Adolescent  Adult  Anxiety/complications  Autism Spectrum Disorder/complications  Autistic Disorder/complications  Child  Child, Preschool  Cross-Sectional Studies  Humans  Uncertainty  Williams Syndrome/complications  Young Adult  Intolerance of Uncertainty  Williams syndrome  anxiety  autism  children  social function  social profile Index. décimale : PER Périodiques Résumé : Anxiety is the most significant mental health concern for both Williams syndrome (WS) and autism. Whilst WS and autism are characterized by some syndrome-specific social differences, less is known about cross-syndrome profiles of anxiety symptoms. Previous research has shown that Intolerance of Uncertainty (IU) is a core mechanism of anxiety maintenance for clinically anxious populations and for autistic children, adolescents, and adults. The only published study in this area for WS has shown some similar patterns-with an added emphasis on the role of sensory sensitivities-in a sample of older teens and adults (mean age = 24), with the authors highlighting the need for younger samples to consider developmental influences. Here we report a cross-syndrome, cross-sectional mediation analyses of children diagnosed with WS or autism, including data from parent surveys of 90 children with WS (n = 48) or autism (n = 42). Group differences showed higher trait levels on all measures for the autism group. Importantly, the relationship between social profile and anxiety was fully mediated by IU level for both groups. This suggests possible similar core mechanisms underlying anxiety in these conditions, and the possibility of generalized intervention approaches especially related to managing distress related to uncertainty in multiple contexts. LAY SUMMARY: Autism and Williams Syndrome share some similarities in social profile and also in anxiety traits, but there are also some key differences as well. Comparing them side-by-side at the same time improved identification of ways to reduce feelings of anxiety. We found that the intolerance of uncertainty affected the relationship between social profile and anxiety in the same way for young children diagnosed with autism or Williams syndrome, meaning that intervention approaches could be similar for both. En ligne : http://dx.doi.org/10.1002/aur.2554 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450 [article] "Intolerance of uncertainty" mediates the relationship between social profile and anxiety in both Williams syndrome and autism [Texte imprimé et/ou numérique] / M. SOUTH, Auteur ; M. HANLEY, Auteur ; K. NORMANSELL-MOSSA, Auteur ; N. C. C. RUSSELL, Auteur ; Thomas CAWTHORNE, Auteur ; D. M. RIBY, Auteur . - p.1986-1995. Langues : Anglais (eng) in Autism Research > 14-9 (September 2021) . - p.1986-1995 Mots-clés : Adolescent  Adult  Anxiety/complications  Autism Spectrum Disorder/complications  Autistic Disorder/complications  Child  Child, Preschool  Cross-Sectional Studies  Humans  Uncertainty  Williams Syndrome/complications  Young Adult  Intolerance of Uncertainty  Williams syndrome  anxiety  autism  children  social function  social profile Index. décimale : PER Périodiques Résumé : Anxiety is the most significant mental health concern for both Williams syndrome (WS) and autism. Whilst WS and autism are characterized by some syndrome-specific social differences, less is known about cross-syndrome profiles of anxiety symptoms. Previous research has shown that Intolerance of Uncertainty (IU) is a core mechanism of anxiety maintenance for clinically anxious populations and for autistic children, adolescents, and adults. The only published study in this area for WS has shown some similar patterns-with an added emphasis on the role of sensory sensitivities-in a sample of older teens and adults (mean age = 24), with the authors highlighting the need for younger samples to consider developmental influences. Here we report a cross-syndrome, cross-sectional mediation analyses of children diagnosed with WS or autism, including data from parent surveys of 90 children with WS (n = 48) or autism (n = 42). Group differences showed higher trait levels on all measures for the autism group. Importantly, the relationship between social profile and anxiety was fully mediated by IU level for both groups. This suggests possible similar core mechanisms underlying anxiety in these conditions, and the possibility of generalized intervention approaches especially related to managing distress related to uncertainty in multiple contexts. LAY SUMMARY: Autism and Williams Syndrome share some similarities in social profile and also in anxiety traits, but there are also some key differences as well. Comparing them side-by-side at the same time improved identification of ways to reduce feelings of anxiety. We found that the intolerance of uncertainty affected the relationship between social profile and anxiety in the same way for young children diagnosed with autism or Williams syndrome, meaning that intervention approaches could be similar for both. En ligne : http://dx.doi.org/10.1002/aur.2554 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=450

A Systematic Review and Meta-analysis of Social Skills Training for Adults with Autism Spectrum Disorder / Julien DUBREUCQ in Journal of Autism and Developmental Disorders, 52-4 (April 2022)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 52-4 (April 2022) . - p.1598-1609 Titre : A Systematic Review and Meta-analysis of Social Skills Training for Adults with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Julien DUBREUCQ, Auteur ; Frédéric HAESEBAERT, Auteur ; J. PLASSE, Auteur ; M. DUBREUCQ, Auteur ; Nicolas FRANCK, Auteur Article en page(s) : p.1598-1609 Langues : Anglais (eng) Mots-clés : Adult  Autism Spectrum Disorder/therapy  Humans  Parents  Social Perception  Social Skills  Adults  Autism spectrum disorder  Social function  Social skills training Index. décimale : PER Périodiques Résumé : This systematic review and meta-analysis is the first to evaluate the effects of group-based social skills training (SST) on parent-report social responsiveness in adults with autism spectrum disorder (ASD). A total of 18 studies were included in the narrative review and among them five randomized-controlled trials (n=145) were included in the meta-analysis. SST had large positive effects on social responsiveness. The narrative review identified that SST could improve patient's outcomes in adults with ASD. These results should be interpreted with caution due to the moderate quality of the existing evidence, which could have inflated effect sizes. The absence of active comparator control groups makes unclear whether improvements at post-treatment are treatment-specific or are attributable to common factors to all psychotherapies. En ligne : http://dx.doi.org/10.1007/s10803-021-05058-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=475 [article] A Systematic Review and Meta-analysis of Social Skills Training for Adults with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Julien DUBREUCQ, Auteur ; Frédéric HAESEBAERT, Auteur ; J. PLASSE, Auteur ; M. DUBREUCQ, Auteur ; Nicolas FRANCK, Auteur . - p.1598-1609. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 52-4 (April 2022) . - p.1598-1609 Mots-clés : Adult  Autism Spectrum Disorder/therapy  Humans  Parents  Social Perception  Social Skills  Adults  Autism spectrum disorder  Social function  Social skills training Index. décimale : PER Périodiques Résumé : This systematic review and meta-analysis is the first to evaluate the effects of group-based social skills training (SST) on parent-report social responsiveness in adults with autism spectrum disorder (ASD). A total of 18 studies were included in the narrative review and among them five randomized-controlled trials (n=145) were included in the meta-analysis. SST had large positive effects on social responsiveness. The narrative review identified that SST could improve patient's outcomes in adults with ASD. These results should be interpreted with caution due to the moderate quality of the existing evidence, which could have inflated effect sizes. The absence of active comparator control groups makes unclear whether improvements at post-treatment are treatment-specific or are attributable to common factors to all psychotherapies. En ligne : http://dx.doi.org/10.1007/s10803-021-05058-w Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=475

Oxytocin therapy for core symptoms in autism spectrum disorder: An updated meta-analysis of randomized controlled trials / Yue WANG in Research in Autism Spectrum Disorders, 64 (August 2019)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 64 (August 2019) . - p.63-75 Titre : Oxytocin therapy for core symptoms in autism spectrum disorder: An updated meta-analysis of randomized controlled trials Type de document : Texte imprimé et/ou numérique Auteurs : Yue WANG, Auteur ; Meng-Jie WANG, Auteur ; Ying RONG, Auteur ; Hui-Zhong HE, Auteur ; Chang-Jiang YANG, Auteur Article en page(s) : p.63-75 Langues : Anglais (eng) Mots-clés : Oxytocin  Autism spectrum disorder  Social function  Repetitive behaviors  Meta-analysis  Randomized controlled trials Index. décimale : PER Périodiques Résumé : Background Evidence of oxytocin for treating core symptoms in autism spectrum disorder (ASD) across development remains mixed and establishing its role is critical for guiding therapy. Aim The current paper is aimed to include new studies and provide a stricter and updated meta-analysis to assess the oxytocin's effects on core symptoms in ASD. Method Computerized search was conducted in PubMed, EMBASE, Cochrane Library, PsycINFO, Web of Science Database and references in reviews from the earliest date available to September 2018. Randomized controlled trials (RCTs) were identified which evaluated the effectiveness of oxytocin on at least one of two domains in patients with ASD, namely social function and repetitive behaviors. Standardized mean difference (SMD) and 95% confidence intervals (CIs) were calculated, and heterogeneity was assessed using the I2 test. Results Sixteen studies comprising 520 individuals with ASD were included in this meta-analysis. Results suggested that oxytocin had a small and non-significant effect on social function [SMD?=?0.03, 95% CI (?0.19, 0.25), p?=?0.781] and repetitive behaviors [SMD?=?0.01, 95% CI (?0.26, 0.27), p?=?0.952] compared with placebo. Studies included had a low heterogeneity (I2?=?46.4%, p?=?0.025 in social function; I2?=?37.0%, p?=?0.123 in repetitive behaviors). Conclusions The current meta-analysis demonstrated that oxytocin had a small and non-significant effect on core symptoms in ASD population. With the limited number of included studies, more large-scale, rigorously and multi-site RCTs are needed to confirm the effectiveness of oxytocin as a treatment of ASD to acquire more convincing conclusions in the future. En ligne : https://doi.org/10.1016/j.rasd.2019.03.007 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=399 [article] Oxytocin therapy for core symptoms in autism spectrum disorder: An updated meta-analysis of randomized controlled trials [Texte imprimé et/ou numérique] / Yue WANG, Auteur ; Meng-Jie WANG, Auteur ; Ying RONG, Auteur ; Hui-Zhong HE, Auteur ; Chang-Jiang YANG, Auteur . - p.63-75. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 64 (August 2019) . - p.63-75 Mots-clés : Oxytocin  Autism spectrum disorder  Social function  Repetitive behaviors  Meta-analysis  Randomized controlled trials Index. décimale : PER Périodiques Résumé : Background Evidence of oxytocin for treating core symptoms in autism spectrum disorder (ASD) across development remains mixed and establishing its role is critical for guiding therapy. Aim The current paper is aimed to include new studies and provide a stricter and updated meta-analysis to assess the oxytocin's effects on core symptoms in ASD. Method Computerized search was conducted in PubMed, EMBASE, Cochrane Library, PsycINFO, Web of Science Database and references in reviews from the earliest date available to September 2018. Randomized controlled trials (RCTs) were identified which evaluated the effectiveness of oxytocin on at least one of two domains in patients with ASD, namely social function and repetitive behaviors. Standardized mean difference (SMD) and 95% confidence intervals (CIs) were calculated, and heterogeneity was assessed using the I2 test. Results Sixteen studies comprising 520 individuals with ASD were included in this meta-analysis. Results suggested that oxytocin had a small and non-significant effect on social function [SMD?=?0.03, 95% CI (?0.19, 0.25), p?=?0.781] and repetitive behaviors [SMD?=?0.01, 95% CI (?0.26, 0.27), p?=?0.952] compared with placebo. Studies included had a low heterogeneity (I2?=?46.4%, p?=?0.025 in social function; I2?=?37.0%, p?=?0.123 in repetitive behaviors). Conclusions The current meta-analysis demonstrated that oxytocin had a small and non-significant effect on core symptoms in ASD population. With the limited number of included studies, more large-scale, rigorously and multi-site RCTs are needed to confirm the effectiveness of oxytocin as a treatment of ASD to acquire more convincing conclusions in the future. En ligne : https://doi.org/10.1016/j.rasd.2019.03.007 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=399