Allelic Variation Within the Putative Autism Spectrum Disorder Risk Gene Homeobox A1 and Cerebellar Maturation in Typically Developing Children and Adolescents / Armin RAZNAHAN in Autism Research, 5-2 (April 2012)  

Public ISBD [article]  inAutism Research > 5-2 (April 2012) . - p.93-100 Titre : Allelic Variation Within the Putative Autism Spectrum Disorder Risk Gene Homeobox A1 and Cerebellar Maturation in Typically Developing Children and Adolescents Type de document : Texte imprimé et/ou numérique Auteurs : Armin RAZNAHAN, Auteur ; Yohan LEE, Auteur ; Catherine VAITUZIS, Auteur ; Lan TRAN, Auteur ; Susan MACKIE, Auteur ; Henning TIEMEIER, Auteur ; Liv S. CLASEN, Auteur ; Francois LALONDE, Auteur ; Deanna GREENSTEIN, Auteur ; Ron PIERSON, Auteur ; Jay N. GIEDD, Auteur Année de publication : 2012 Article en page(s) : p.93-100 Langues : Anglais (eng) Mots-clés : autism  HOXA1  cerebellum  gene  brain  MRI Index. décimale : PER Périodiques Résumé : Homeobox A1 (HOXA1) has been proposed as a candidate gene for autism spectrum disorder (ASD) as it regulates embryological patterning of hind-brain structures implicated in autism neurobiology. In line with this notion, a nonsynonymous single nucleotide polymorphism within a highly conserved domain of HOXA1—A218G (rs10951154)—has been linked to both ASD risk, and cross-sectional differences in superior posterior lobar cerebellar anatomy in late adulthood. Despite evidence for early onset and developmentally dynamic cerebellar involvement in ASD, little is known of the relationship between A218G genotype and maturation of the cerebellum over early development. We addressed this issue using 296 longitudinally acquired structural magnetic resonance imaging brain scans from 116 healthy individuals between 5 and 23 years of age. Mixed models were used to compare the relationship between age and semi-automated measures of cerebellar volume in A-homozygotes (AA) and carriers of the G allele (Gcar). Total cerebellar volume increased between ages of 5 and 23 years in both groups. However, this was accelerated in the Gcar relative to the AA group (Genotype-by-age interaction term, P = 0.03), and driven by genotype-dependent differences in the rate of bilateral superior posterior lobar volume change with age (P = 0.002). Resultantly, although superior posterior lobar volume did not differ significantly between genotype groups at age 5 (P = 0.9), by age 23 it was 12% greater in Gcar than AA (P = 0.002). Our results suggest that common genetic variation within this putative ASD risk gene has the capacity to modify the development of cerebellar systems implicated in ASD neurobiology. En ligne : http://dx.doi.org/10.1002/aur.238 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=155 [article] Allelic Variation Within the Putative Autism Spectrum Disorder Risk Gene Homeobox A1 and Cerebellar Maturation in Typically Developing Children and Adolescents [Texte imprimé et/ou numérique] / Armin RAZNAHAN, Auteur ; Yohan LEE, Auteur ; Catherine VAITUZIS, Auteur ; Lan TRAN, Auteur ; Susan MACKIE, Auteur ; Henning TIEMEIER, Auteur ; Liv S. CLASEN, Auteur ; Francois LALONDE, Auteur ; Deanna GREENSTEIN, Auteur ; Ron PIERSON, Auteur ; Jay N. GIEDD, Auteur . - 2012 . - p.93-100. Langues : Anglais (eng) in Autism Research > 5-2 (April 2012) . - p.93-100 Mots-clés : autism  HOXA1  cerebellum  gene  brain  MRI Index. décimale : PER Périodiques Résumé : Homeobox A1 (HOXA1) has been proposed as a candidate gene for autism spectrum disorder (ASD) as it regulates embryological patterning of hind-brain structures implicated in autism neurobiology. In line with this notion, a nonsynonymous single nucleotide polymorphism within a highly conserved domain of HOXA1—A218G (rs10951154)—has been linked to both ASD risk, and cross-sectional differences in superior posterior lobar cerebellar anatomy in late adulthood. Despite evidence for early onset and developmentally dynamic cerebellar involvement in ASD, little is known of the relationship between A218G genotype and maturation of the cerebellum over early development. We addressed this issue using 296 longitudinally acquired structural magnetic resonance imaging brain scans from 116 healthy individuals between 5 and 23 years of age. Mixed models were used to compare the relationship between age and semi-automated measures of cerebellar volume in A-homozygotes (AA) and carriers of the G allele (Gcar). Total cerebellar volume increased between ages of 5 and 23 years in both groups. However, this was accelerated in the Gcar relative to the AA group (Genotype-by-age interaction term, P = 0.03), and driven by genotype-dependent differences in the rate of bilateral superior posterior lobar volume change with age (P = 0.002). Resultantly, although superior posterior lobar volume did not differ significantly between genotype groups at age 5 (P = 0.9), by age 23 it was 12% greater in Gcar than AA (P = 0.002). Our results suggest that common genetic variation within this putative ASD risk gene has the capacity to modify the development of cerebellar systems implicated in ASD neurobiology. En ligne : http://dx.doi.org/10.1002/aur.238 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=155

Are some children genetically predisposed to poor sleep? A polygenic risk study in the general population / Desana KOCEVSKA in Journal of Child Psychology and Psychiatry, 65-5 (May 2024)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 65-5 (May 2024) . - p.710-719 Titre : Are some children genetically predisposed to poor sleep? A polygenic risk study in the general population Type de document : Texte imprimé et/ou numérique Auteurs : Desana KOCEVSKA, Auteur ; Katerina TRAJANOSKA, Auteur ; Rosa H. MULDER, Auteur ; M. Elisabeth KOOPMAN-VERHOEFF, Auteur ; Annemarie I. LUIK, Auteur ; Henning TIEMEIER, Auteur ; Eus J.W. VAN SOMEREN, Auteur Article en page(s) : p.710-719 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Background Twin studies show moderate heritability of sleep traits: 40% for insomnia symptoms and 46% for sleep duration. Genome-wide association studies (GWAS) have identified genetic variants involved in insomnia and sleep duration in adults, but it is unknown whether these variants affect sleep during early development. We assessed whether polygenic risk scores for insomnia (PRS-I) and sleep duration (PRS-SD) affect sleep throughout early childhood to adolescence. Methods We included 2,458 children of European ancestry (51% girls). Insomnia-related items of the Child Behavior Checklist were reported by mothers at child's age 1.5, 3, and 6?years. At 10-15?years, the Sleep Disturbance Scale for Children and actigraphy were assessed in a subsample (N = 975). Standardized PRS-I and PRS-SD (higher scores indicate genetic susceptibility for insomnia and longer sleep duration, respectively) were computed at multiple p-value thresholds based on largest GWAS to date. Results Children with higher PRS-I had more insomnia-related sleep problems between 1.5 and 15?years (BPRS-I < 0.001 = .09, 95% CI: 0.05; 0.14). PRS-SD was not associated with mother-reported sleep problems. A higher PRS-SD was in turn associated with longer actigraphically estimated sleep duration (BPRS-SD < 5e08 = .05, 95% CI: 0.001; 0.09) and more wake after sleep onset (BPRS-SD < 0.005 = .25, 95% CI: 0.04; 0.47) at 10-15?years, but these associations did not survive multiple testing correction. Conclusions Children who are genetically predisposed to insomnia have more insomnia-like sleep problems, whereas those who are genetically predisposed to longer sleep have longer sleep duration, but are also more awake during the night in adolescence. This indicates that polygenic risk for sleep traits, based on GWAS in adults, affects sleep already in children. En ligne : https://doi.org/10.1111/jcpp.13899 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=526 [article] Are some children genetically predisposed to poor sleep? A polygenic risk study in the general population [Texte imprimé et/ou numérique] / Desana KOCEVSKA, Auteur ; Katerina TRAJANOSKA, Auteur ; Rosa H. MULDER, Auteur ; M. Elisabeth KOOPMAN-VERHOEFF, Auteur ; Annemarie I. LUIK, Auteur ; Henning TIEMEIER, Auteur ; Eus J.W. VAN SOMEREN, Auteur . - p.710-719. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 65-5 (May 2024) . - p.710-719 Index. décimale : PER Périodiques Résumé : Background Twin studies show moderate heritability of sleep traits: 40% for insomnia symptoms and 46% for sleep duration. Genome-wide association studies (GWAS) have identified genetic variants involved in insomnia and sleep duration in adults, but it is unknown whether these variants affect sleep during early development. We assessed whether polygenic risk scores for insomnia (PRS-I) and sleep duration (PRS-SD) affect sleep throughout early childhood to adolescence. Methods We included 2,458 children of European ancestry (51% girls). Insomnia-related items of the Child Behavior Checklist were reported by mothers at child's age 1.5, 3, and 6?years. At 10-15?years, the Sleep Disturbance Scale for Children and actigraphy were assessed in a subsample (N = 975). Standardized PRS-I and PRS-SD (higher scores indicate genetic susceptibility for insomnia and longer sleep duration, respectively) were computed at multiple p-value thresholds based on largest GWAS to date. Results Children with higher PRS-I had more insomnia-related sleep problems between 1.5 and 15?years (BPRS-I < 0.001 = .09, 95% CI: 0.05; 0.14). PRS-SD was not associated with mother-reported sleep problems. A higher PRS-SD was in turn associated with longer actigraphically estimated sleep duration (BPRS-SD < 5e08 = .05, 95% CI: 0.001; 0.09) and more wake after sleep onset (BPRS-SD < 0.005 = .25, 95% CI: 0.04; 0.47) at 10-15?years, but these associations did not survive multiple testing correction. Conclusions Children who are genetically predisposed to insomnia have more insomnia-like sleep problems, whereas those who are genetically predisposed to longer sleep have longer sleep duration, but are also more awake during the night in adolescence. This indicates that polygenic risk for sleep traits, based on GWAS in adults, affects sleep already in children. En ligne : https://doi.org/10.1111/jcpp.13899 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=526

Behavioral outcomes of picky eating in childhood: a prospective study in the general population / Sebastian CARDONA CANO in Journal of Child Psychology and Psychiatry, 57-11 (November 2016)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 57-11 (November 2016) . - p.1239-1246 Titre : Behavioral outcomes of picky eating in childhood: a prospective study in the general population Type de document : Texte imprimé et/ou numérique Auteurs : Sebastian CARDONA CANO, Auteur ; Hans W. HOEK, Auteur ; Daphne VAN HOEKEN, Auteur ; Lisanne M. DE BARSE, Auteur ; Vincent W.V. JADDOE, Auteur ; Frank C. VERHULST, Auteur ; Henning TIEMEIER, Auteur Article en page(s) : p.1239-1246 Langues : Anglais (eng) Mots-clés : Picky eating  emotional problems  behavioral problems  pervasive developmental problems Index. décimale : PER Périodiques Résumé : Background Picky eaters in the general population form a heterogeneous group. It is important to differentiate between children with transient picky eating (PE) and persistent PE behavior when adverse outcomes are studied. We analyzed four PE trajectories to determine the associations with child mental health prospectively. Methods From a population-based cohort, 3,748 participants were assessed for PE at 1.5, 3, and 6 years of age using maternal reports. Four trajectories were defined: persistent (PE at all ages); remitting (PE before 6 years only); late-onset (PE at 6 years only); and never (no PE at any assessment). Child's problem behaviors were assessed with the Teacher's Report Form at 7 years of age. We examined associations between picky eating trajectories and emotional problems, behavioral problems and pervasive developmental problems using logistic regressions. Analyses were adjusted for child, parental, and socioeconomic confounders. We also adjusted for maternal-reported baseline problem behavior at age 1.5 years; the never picky eating group was used as reference. Results Persisting PE predicted pervasive developmental problems at age 7 years (OR = 2.00, 95% CI: 1.10–3.63). The association remained when adjusted for baseline pervasive developmental problems at 1.5 years (OR = 1.96, 95% CI: 1.10–3.51). Persistent PE was not associated with behavioral (OR = 0.92, 95% CI: 0.53–1.60) or emotional problems (OR = 1.24, 95% CI: 0.74–2.07). Other PE trajectories were not related to child behavioral or emotional problems. Conclusions Persistent PE may be a symptom or sign of pervasive developmental problems, but is not predictive of other behavioral problems. Remitting PE was not associated with adverse mental health outcomes, which further indicates that it may be part of normal development. En ligne : http://dx.doi.org/10.1111/jcpp.12530 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=295 [article] Behavioral outcomes of picky eating in childhood: a prospective study in the general population [Texte imprimé et/ou numérique] / Sebastian CARDONA CANO, Auteur ; Hans W. HOEK, Auteur ; Daphne VAN HOEKEN, Auteur ; Lisanne M. DE BARSE, Auteur ; Vincent W.V. JADDOE, Auteur ; Frank C. VERHULST, Auteur ; Henning TIEMEIER, Auteur . - p.1239-1246. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 57-11 (November 2016) . - p.1239-1246 Mots-clés : Picky eating  emotional problems  behavioral problems  pervasive developmental problems Index. décimale : PER Périodiques Résumé : Background Picky eaters in the general population form a heterogeneous group. It is important to differentiate between children with transient picky eating (PE) and persistent PE behavior when adverse outcomes are studied. We analyzed four PE trajectories to determine the associations with child mental health prospectively. Methods From a population-based cohort, 3,748 participants were assessed for PE at 1.5, 3, and 6 years of age using maternal reports. Four trajectories were defined: persistent (PE at all ages); remitting (PE before 6 years only); late-onset (PE at 6 years only); and never (no PE at any assessment). Child's problem behaviors were assessed with the Teacher's Report Form at 7 years of age. We examined associations between picky eating trajectories and emotional problems, behavioral problems and pervasive developmental problems using logistic regressions. Analyses were adjusted for child, parental, and socioeconomic confounders. We also adjusted for maternal-reported baseline problem behavior at age 1.5 years; the never picky eating group was used as reference. Results Persisting PE predicted pervasive developmental problems at age 7 years (OR = 2.00, 95% CI: 1.10–3.63). The association remained when adjusted for baseline pervasive developmental problems at 1.5 years (OR = 1.96, 95% CI: 1.10–3.51). Persistent PE was not associated with behavioral (OR = 0.92, 95% CI: 0.53–1.60) or emotional problems (OR = 1.24, 95% CI: 0.74–2.07). Other PE trajectories were not related to child behavioral or emotional problems. Conclusions Persistent PE may be a symptom or sign of pervasive developmental problems, but is not predictive of other behavioral problems. Remitting PE was not associated with adverse mental health outcomes, which further indicates that it may be part of normal development. En ligne : http://dx.doi.org/10.1111/jcpp.12530 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=295

Childhood peer network characteristics: genetic influences and links with early mental health trajectories / Eszter SZEKELY in Journal of Child Psychology and Psychiatry, 57-6 (June 2016)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 57-6 (June 2016) . - p.687-694 Titre : Childhood peer network characteristics: genetic influences and links with early mental health trajectories Type de document : Texte imprimé et/ou numérique Auteurs : Eszter SZEKELY, Auteur ; Irene PAPPA, Auteur ; James D. WILSON, Auteur ; Shankar BHAMIDI, Auteur ; Vincent W.V. JADDOE, Auteur ; Frank C. VERHULST, Auteur ; Henning TIEMEIER, Auteur ; Philip SHAW, Auteur Article en page(s) : p.687-694 Langues : Anglais (eng) Mots-clés : Heritability  peer networks  externalizing  internalizing  preschoolers Index. décimale : PER Périodiques Résumé : Background Peer relationships are important for children's mental health, yet little is known of their etiological underpinnings. Here, we explore the genetic influences on childhood peer network characteristics in three different networks defined by rejection, acceptance, and prosocial behavior. We further examine the impact of early externalizing and internalizing trajectories on these same peer network characteristics. Methods Participants were 1,288 children from the Dutch ‘Generation R’ birth cohort. At age 7, we mapped out children's classroom peer networks for peer rejection, acceptance, and prosocial behavior using mutual peer nominations. In each network, genetic influences were estimated for children's degree centrality, closeness centrality and link reciprocity from DNA using Genome-wide Complex Trait Analysis. Preschool externalizing and internalizing trajectories were computed using parental ratings at ages 1.5, 3, and 5 years. Results Of the three network properties examined, closeness centrality emerged as significantly heritable across all networks. Preschool externalizing problems predicted unfavorable positions within peer rejection networks and having fewer mutual friendships. In contrast, children with preschool-internalizing problems were not actively rejected by their peers, but were less well-connected within their social support network. Conclusions Our finding of significant heritability for closeness centrality should be taken as preliminary evidence that requires replication. Nevertheless, it can orient us to the role of genes in shaping a child's position within peer networks. Additionally, social network perspectives offer rich insights into how early life mental health trajectories impact a child's later functioning within peer networks. En ligne : http://dx.doi.org/10.1111/jcpp.12493 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=289 [article] Childhood peer network characteristics: genetic influences and links with early mental health trajectories [Texte imprimé et/ou numérique] / Eszter SZEKELY, Auteur ; Irene PAPPA, Auteur ; James D. WILSON, Auteur ; Shankar BHAMIDI, Auteur ; Vincent W.V. JADDOE, Auteur ; Frank C. VERHULST, Auteur ; Henning TIEMEIER, Auteur ; Philip SHAW, Auteur . - p.687-694. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 57-6 (June 2016) . - p.687-694 Mots-clés : Heritability  peer networks  externalizing  internalizing  preschoolers Index. décimale : PER Périodiques Résumé : Background Peer relationships are important for children's mental health, yet little is known of their etiological underpinnings. Here, we explore the genetic influences on childhood peer network characteristics in three different networks defined by rejection, acceptance, and prosocial behavior. We further examine the impact of early externalizing and internalizing trajectories on these same peer network characteristics. Methods Participants were 1,288 children from the Dutch ‘Generation R’ birth cohort. At age 7, we mapped out children's classroom peer networks for peer rejection, acceptance, and prosocial behavior using mutual peer nominations. In each network, genetic influences were estimated for children's degree centrality, closeness centrality and link reciprocity from DNA using Genome-wide Complex Trait Analysis. Preschool externalizing and internalizing trajectories were computed using parental ratings at ages 1.5, 3, and 5 years. Results Of the three network properties examined, closeness centrality emerged as significantly heritable across all networks. Preschool externalizing problems predicted unfavorable positions within peer rejection networks and having fewer mutual friendships. In contrast, children with preschool-internalizing problems were not actively rejected by their peers, but were less well-connected within their social support network. Conclusions Our finding of significant heritability for closeness centrality should be taken as preliminary evidence that requires replication. Nevertheless, it can orient us to the role of genes in shaping a child's position within peer networks. Additionally, social network perspectives offer rich insights into how early life mental health trajectories impact a child's later functioning within peer networks. En ligne : http://dx.doi.org/10.1111/jcpp.12493 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=289

Cognitive performance in children and adolescents with psychopathology traits: A cross-sectional multicohort study in the general population / Elisabet BLOK in Development and Psychopathology, 35-2 (May 2023)  

Public ISBD [article]  inDevelopment and Psychopathology > 35-2 (May 2023) . - p.926-940 Titre : Cognitive performance in children and adolescents with psychopathology traits: A cross-sectional multicohort study in the general population Type de document : Texte imprimé et/ou numérique Auteurs : Elisabet BLOK, Auteur ; Isabel K. SCHUURMANS, Auteur ; Anne J. TIJBURG, Auteur ; Manon HILLEGERS, Auteur ; Maria E. KOOPMAN-VERHOEFF, Auteur ; Ryan L. MUETZEL, Auteur ; Henning TIEMEIER, Auteur ; Tonya WHITE, Auteur Article en page(s) : p.926-940 Langues : Anglais (eng) Mots-clés : adolescence  childhood  cognition  Child Behavior Checklist  psychopathology Index. décimale : PER Périodiques Résumé : Psychopathology and cognitive development are closely related. Assessing the relationship between multiple domains of psychopathology and cognitive performance can elucidate which cognitive tasks are related to specific domains of psychopathology. This can help build theory and improve clinical decision-making in the future. In this study, we included 13,841 children and adolescents drawn from two large population-based samples (Generation R and ABCD studies). We assessed the cross-sectional relationship between three psychopathology domains (internalizing, externalizing, dysregulation profile (DP)) and four cognitive domains (vocabulary, fluid reasoning, working memory, and processing speed) and the full-scale intelligence quotient. Lastly, differential associations between symptoms of psychopathology and cognitive performance by sex were assessed. Results indicated that internalizing symptoms were related to worse performance in working memory and processing speed, but better performance in the verbal domain. Externalizing and DP symptoms were related to poorer global cognitive performance. Notably, those in the DP subgroup had a 5.0 point lower IQ than those without behavioral problems. Cognitive performance was more heavily affected in boys than in girls given comparable levels of psychopathology. Taken together, we provide evidence for globally worse cognitive performance in children and adolescents with externalizing and DP symptoms, with those in the DP subgroup being most heavily affected. En ligne : http://dx.doi.org/10.1017/S0954579422000165 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=504 [article] Cognitive performance in children and adolescents with psychopathology traits: A cross-sectional multicohort study in the general population [Texte imprimé et/ou numérique] / Elisabet BLOK, Auteur ; Isabel K. SCHUURMANS, Auteur ; Anne J. TIJBURG, Auteur ; Manon HILLEGERS, Auteur ; Maria E. KOOPMAN-VERHOEFF, Auteur ; Ryan L. MUETZEL, Auteur ; Henning TIEMEIER, Auteur ; Tonya WHITE, Auteur . - p.926-940. Langues : Anglais (eng) in Development and Psychopathology > 35-2 (May 2023) . - p.926-940 Mots-clés : adolescence  childhood  cognition  Child Behavior Checklist  psychopathology Index. décimale : PER Périodiques Résumé : Psychopathology and cognitive development are closely related. Assessing the relationship between multiple domains of psychopathology and cognitive performance can elucidate which cognitive tasks are related to specific domains of psychopathology. This can help build theory and improve clinical decision-making in the future. In this study, we included 13,841 children and adolescents drawn from two large population-based samples (Generation R and ABCD studies). We assessed the cross-sectional relationship between three psychopathology domains (internalizing, externalizing, dysregulation profile (DP)) and four cognitive domains (vocabulary, fluid reasoning, working memory, and processing speed) and the full-scale intelligence quotient. Lastly, differential associations between symptoms of psychopathology and cognitive performance by sex were assessed. Results indicated that internalizing symptoms were related to worse performance in working memory and processing speed, but better performance in the verbal domain. Externalizing and DP symptoms were related to poorer global cognitive performance. Notably, those in the DP subgroup had a 5.0 point lower IQ than those without behavioral problems. Cognitive performance was more heavily affected in boys than in girls given comparable levels of psychopathology. Taken together, we provide evidence for globally worse cognitive performance in children and adolescents with externalizing and DP symptoms, with those in the DP subgroup being most heavily affected. En ligne : http://dx.doi.org/10.1017/S0954579422000165 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=504

Combined polygenic risk scores of different psychiatric traits predict general and specific psychopathology in childhood / Alexander NEUMANN in Journal of Child Psychology and Psychiatry, 63-6 (June 2022)  

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Connecting the dots: social networks in the classroom and white matter connections in the brain / Rosa H. MULDER in Journal of Child Psychology and Psychiatry, 63-12 (December 2022)  

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Dopaminergic, serotonergic, and oxytonergic candidate genes associated with infant attachment security and disorganization? In search of main and interaction effects / Maartje P.C.M. LUIJK in Journal of Child Psychology and Psychiatry, 52-12 (December 2011)  

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A DRD4 gene by maternal sensitivity interaction predicts risk for overweight or obesity in two independent cohorts of preschool children / Robert D. LEVITAN in Journal of Child Psychology and Psychiatry, 58-2 (February 2017)  

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Environment-Wide Association Study (EnWAS) of Prenatal and Perinatal Factors Associated With Autistic Traits: A Population-Based Study / Masoud AMIRI in Autism Research, 13-9 (September 2020)  

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Genome-wide DNA methylation patterns associated with sleep and mental health in children: a population-based study / Maria Elisabeth KOOPMAN-VERHOEFF in Journal of Child Psychology and Psychiatry, 61-10 (October 2020)  

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Infant brain structures, executive function, and attention deficit/hyperactivity problems at preschool age. A prospective study / Akhgar GHASSABIAN in Journal of Child Psychology and Psychiatry, 54-1 (January 2013)  

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Infant muscle tone and childhood autistic traits: A longitudinal study in the general population / Fadila SERDAREVIC in Autism Research, 10-5 (May 2017)  

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Insensitive parenting may accelerate the development of the amygdala–medial prefrontal cortex circuit / Sandra THIJSSEN in Development and Psychopathology, 29-2 (May 2017)  

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Maternal age, autistic-like traits and mentalizing as predictors of child autistic-like traits in a population-based cohort / Novika Purnama SARI in Molecular Autism, 13 (2022)  

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