Brief Report: Linguistic Mazes and Perseverations in School-Age Boys with Fragile X Syndrome and Autism Spectrum Disorder and Relationships with Maternal Maze Use / Nell MALTMAN in Journal of Autism and Developmental Disorders, 52-2 (February 2022)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 52-2 (February 2022) . - p.897-907 Titre : Brief Report: Linguistic Mazes and Perseverations in School-Age Boys with Fragile X Syndrome and Autism Spectrum Disorder and Relationships with Maternal Maze Use Type de document : texte imprimé Auteurs : Nell MALTMAN, Auteur ; Laura FRIEDMAN, Auteur ; Emily LORANG, Auteur ; Audra STERLING, Auteur Article en page(s) : p.897-907 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder  Fragile X Syndrome  Humans  Language Tests  Linguistics  Male  Schools  Autism spectrum disorder  Fragile X syndrome  Linguistic mazes  Parent–child associations  Perseveration Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) and fragile X syndrome (FXS) are neurodevelopmental disorders with overlapping pragmatic language impairments. Prior work suggests pragmatic language differences may run in families. This study examined specific pragmatic difficulties (i.e., linguistic mazes and perseverations) in boys (9-18 years) with idiopathic ASD (n = 26) and FXS+ASD (n = 29), and relationships with maternal maze use. Language samples were obtained separately for boys and mothers. Nonparametric analyses suggested that boys largely did not differ in their rates of mazes, but that boys with FXS+ASD exhibited more perseverations. Mazes were correlated between fragile X dyads. Maternal mazes were correlated with child perseverations among idiopathic ASD dyads. These findings have implications for the etiological significance of ASD-related language phenotypes. En ligne : http://dx.doi.org/10.1007/s10803-021-04981-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=455 [article] Brief Report: Linguistic Mazes and Perseverations in School-Age Boys with Fragile X Syndrome and Autism Spectrum Disorder and Relationships with Maternal Maze Use [texte imprimé] / Nell MALTMAN, Auteur ; Laura FRIEDMAN, Auteur ; Emily LORANG, Auteur ; Audra STERLING, Auteur . - p.897-907. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 52-2 (February 2022) . - p.897-907 Mots-clés : Autism Spectrum Disorder  Fragile X Syndrome  Humans  Language Tests  Linguistics  Male  Schools  Autism spectrum disorder  Fragile X syndrome  Linguistic mazes  Parent–child associations  Perseveration Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) and fragile X syndrome (FXS) are neurodevelopmental disorders with overlapping pragmatic language impairments. Prior work suggests pragmatic language differences may run in families. This study examined specific pragmatic difficulties (i.e., linguistic mazes and perseverations) in boys (9-18 years) with idiopathic ASD (n = 26) and FXS+ASD (n = 29), and relationships with maternal maze use. Language samples were obtained separately for boys and mothers. Nonparametric analyses suggested that boys largely did not differ in their rates of mazes, but that boys with FXS+ASD exhibited more perseverations. Mazes were correlated between fragile X dyads. Maternal mazes were correlated with child perseverations among idiopathic ASD dyads. These findings have implications for the etiological significance of ASD-related language phenotypes. En ligne : http://dx.doi.org/10.1007/s10803-021-04981-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=455

Brief Report: Socioeconomic Factors Associated with Minimally Verbal Status in Individuals with ASD / Nell MALTMAN in Journal of Autism and Developmental Disorders, 51-6 (June 2021)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 51-6 (June 2021) . - p.2139-2145 Titre : Brief Report: Socioeconomic Factors Associated with Minimally Verbal Status in Individuals with ASD Type de document : texte imprimé Auteurs : Nell MALTMAN, Auteur ; Leann S. DAWALT, Auteur ; Jinkuk HONG, Auteur ; Marsha R. MAILICK, Auteur Année de publication : 2021 Article en page(s) : p.2139-2145 Langues : Anglais (eng) Mots-clés : Adolescent  Adult  Autism Spectrum Disorder/economics/psychology  Child  Female  Humans  Language Development  Male  Parents  Socioeconomic Factors  Verbal Learning  Young Adult  Adi-r  Asd  Lifespan development  Minimally verbal  Ses Index. décimale : PER Périodiques Résumé : About 30% of adults with autism are minimally verbal. Past research suggested that after age five, few gain verbal fluency, but studies have rarely investigated whether family environmental factors contribute to the acquisition of verbal fluency. The present study utilized data from the Autism Diagnostic Interview-Revised to compare changes in verbal fluency for 404 individuals with autism from childhood to adolescence and adulthood. Socioeconomic factors were examined across fluency groups (i.e., those who did/did not achieve verbal fluency). Findings indicated that fully 60% of those who were minimally verbal in early childhood acquired verbal fluency in adolescence and adulthood. Parent socioeconomic status differed across fluency groups, suggesting the importance of environmental factors for individual development. En ligne : http://dx.doi.org/10.1007/s10803-020-04646-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452 [article] Brief Report: Socioeconomic Factors Associated with Minimally Verbal Status in Individuals with ASD [texte imprimé] / Nell MALTMAN, Auteur ; Leann S. DAWALT, Auteur ; Jinkuk HONG, Auteur ; Marsha R. MAILICK, Auteur . - 2021 . - p.2139-2145. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 51-6 (June 2021) . - p.2139-2145 Mots-clés : Adolescent  Adult  Autism Spectrum Disorder/economics/psychology  Child  Female  Humans  Language Development  Male  Parents  Socioeconomic Factors  Verbal Learning  Young Adult  Adi-r  Asd  Lifespan development  Minimally verbal  Ses Index. décimale : PER Périodiques Résumé : About 30% of adults with autism are minimally verbal. Past research suggested that after age five, few gain verbal fluency, but studies have rarely investigated whether family environmental factors contribute to the acquisition of verbal fluency. The present study utilized data from the Autism Diagnostic Interview-Revised to compare changes in verbal fluency for 404 individuals with autism from childhood to adolescence and adulthood. Socioeconomic factors were examined across fluency groups (i.e., those who did/did not achieve verbal fluency). Findings indicated that fully 60% of those who were minimally verbal in early childhood acquired verbal fluency in adolescence and adulthood. Parent socioeconomic status differed across fluency groups, suggesting the importance of environmental factors for individual development. En ligne : http://dx.doi.org/10.1007/s10803-020-04646-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=452

Parental Broader Autism Subphenotypes in ASD Affected Families: Relationship to Gender, Child's Symptoms, SSRI Treatment, and Platelet Serotonin / Tal LEVIN-DECANINI in Autism Research, 6-6 (December 2013)  

Public ISBD [article]  inAutism Research > 6-6 (December 2013) . - p.621-630 Titre : Parental Broader Autism Subphenotypes in ASD Affected Families: Relationship to Gender, Child's Symptoms, SSRI Treatment, and Platelet Serotonin Type de document : texte imprimé Auteurs : Tal LEVIN-DECANINI, Auteur ; Nell MALTMAN, Auteur ; Sunday M. FRANCIS, Auteur ; Steve GUTER, Auteur ; George M. ANDERSON, Auteur ; Edwin H. Jr COOK, Auteur ; Suma JACOB, Auteur Année de publication : 2013 Article en page(s) : p.621-630 Langues : Anglais (eng) Mots-clés : broader autism phenotype  serotonin  autism  SSRI Index. décimale : PER Périodiques Résumé : Relationships between parental broader autism phenotype (BAP) scores, gender, selective serotonin reuptake inhibitor (SSRI) treatment, serotonin (5HT) levels, and the child's symptoms were investigated in a family study of autism spectrum disorder (ASD). The Broader Autism Phenotype Questionnaire (BAPQ) was used to measure the BAP of 275 parents. Fathers not taking SSRIs (F-SSRI; n = 115) scored significantly higher on BAP Total and Aloof subscales compared to mothers not receiving treatment (M-SSRI; n = 136.) However, mothers taking SSRIs (M + SSRI; n = 19) scored higher than those not taking medication on BAP Total and Rigid subscales, and they were more likely to be BAPQ Total, Aloof, and Rigid positive. Significant correlations were noted between proband autism symptoms and parental BAPQ scores such that Total, Aloof, and Rigid subscale scores of F-SSRI correlated with proband restricted repetitive behavior (RRB) measures on the ADOS, CRI, and RBS-R. However, only the Aloof subscale score of M + SSRI correlated with proband RRB on the ADOS. The correlation between the BAPQ scores of mothers taking SSRIs and child scores, as well as the increase in BAPQ scores of this group of mothers, requires careful interpretation and further study because correlations would not withstand multiple corrections. As expected by previous research, significant parent–child correlations were observed for 5HT levels. However, 5HT levels were not correlated with behavioral measures. Study results suggest that the expression of the BAP varies not only across parental gender, but also across individuals using psychotropic medication and those who do not. En ligne : http://dx.doi.org/10.1002/aur.1322 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=221 [article] Parental Broader Autism Subphenotypes in ASD Affected Families: Relationship to Gender, Child's Symptoms, SSRI Treatment, and Platelet Serotonin [texte imprimé] / Tal LEVIN-DECANINI, Auteur ; Nell MALTMAN, Auteur ; Sunday M. FRANCIS, Auteur ; Steve GUTER, Auteur ; George M. ANDERSON, Auteur ; Edwin H. Jr COOK, Auteur ; Suma JACOB, Auteur . - 2013 . - p.621-630. Langues : Anglais (eng) in Autism Research > 6-6 (December 2013) . - p.621-630 Mots-clés : broader autism phenotype  serotonin  autism  SSRI Index. décimale : PER Périodiques Résumé : Relationships between parental broader autism phenotype (BAP) scores, gender, selective serotonin reuptake inhibitor (SSRI) treatment, serotonin (5HT) levels, and the child's symptoms were investigated in a family study of autism spectrum disorder (ASD). The Broader Autism Phenotype Questionnaire (BAPQ) was used to measure the BAP of 275 parents. Fathers not taking SSRIs (F-SSRI; n = 115) scored significantly higher on BAP Total and Aloof subscales compared to mothers not receiving treatment (M-SSRI; n = 136.) However, mothers taking SSRIs (M + SSRI; n = 19) scored higher than those not taking medication on BAP Total and Rigid subscales, and they were more likely to be BAPQ Total, Aloof, and Rigid positive. Significant correlations were noted between proband autism symptoms and parental BAPQ scores such that Total, Aloof, and Rigid subscale scores of F-SSRI correlated with proband restricted repetitive behavior (RRB) measures on the ADOS, CRI, and RBS-R. However, only the Aloof subscale score of M + SSRI correlated with proband RRB on the ADOS. The correlation between the BAPQ scores of mothers taking SSRIs and child scores, as well as the increase in BAPQ scores of this group of mothers, requires careful interpretation and further study because correlations would not withstand multiple corrections. As expected by previous research, significant parent–child correlations were observed for 5HT levels. However, 5HT levels were not correlated with behavioral measures. Study results suggest that the expression of the BAP varies not only across parental gender, but also across individuals using psychotropic medication and those who do not. En ligne : http://dx.doi.org/10.1002/aur.1322 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=221

The impact of individual factors on linguistic alignment of autistic boys and their mothers / Nell MALTMAN in Autism, 30-2 (February 2026)  

Public ISBD [article]  inAutism > 30-2 (February 2026) . - p.510-524 Titre : The impact of individual factors on linguistic alignment of autistic boys and their mothers Type de document : texte imprimé Auteurs : Nell MALTMAN, Auteur ; Camille J. WYNN, Auteur ; Elizabeth A. WYNN, Auteur ; Audra STERLING, Auteur Article en page(s) : p.510-524 Langues : Anglais (eng) Mots-clés : communication and language  family studies  fragile X  autism  linguistic alignment Index. décimale : PER Périodiques Résumé : Linguistic alignment reflects shared linguistic behaviors (e.g. syntax and lexicon) between interlocutors. Recent work has examined whether autistic children align to the same degree as their non-autistic peers, with current findings inconclusive. This study took an in-depth approach to investigating factors contributing to variation in linguistic alignment among autistic individuals. Eighteen school-age and adolescent autistic male participants, 14 males with fragile X syndrome + autism, and their mothers participated in the study. Dyads engaged in an unstructured conversation for ~12 min. Using Bayesian linear mixed-effect models, we assessed the relationships between alignment and within-individual factors of the participants. Lexical and syntactic alignment were uniquely influenced by within-participant factors. Maternal lexical and syntactic alignment were differentially associated with participant cognitive and expressive language abilities, and according to etiology (fragile X syndrome + autism vs idiopathic autism). This study highlights the complexity of alignment in autistic individuals and their mothers. Results suggest that alignment is a dynamic process that is motivated in part by within-individual traits of their children. Consequently, characterizing alignment in autism requires a highly nuanced and thoughtful approach that accounts for the heterogeneity of the population.Lay abstractShared Language Use in Conversations Between Mothers and Their Autistic SonsDuring conversations, we tend to use the same kinds of words as our partners, which is an important skill that helps language development. Researchers have explored this phenomenon among autistic individuals and have not found consistent differences from non-autistic individuals. The current study examined how mothers and their autistic sons communicate with each other during conversations to see the extent to which they used similar words and grammar.We included 32 school-age and adolescent male participants (18 autism, 14 fragile X + autism) and their mothers. Participants and their mothers talked together how they normally would for 12 min. We transcribed everything they said and evaluated how much they used the same words and grammar as each other. We also looked at how other characteristics, like IQ and language skills, influenced how much they were similar in their language.We found that mothers and their sons used the same kinds of words at a rate greater than chance. Mothers used similar language as their sons more often when their son had greater language skills. Mothers who had children with fragile X + autism were more likely to use similar words as their son.This study showed that using the same words and grammar is a very dynamic process that depends in part on language and cognition between two speakers. It is important that future research in this area takes a detailed and thoughtful approach to analysis. En ligne : https://dx.doi.org/10.1177/13623613251395538 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=579 [article] The impact of individual factors on linguistic alignment of autistic boys and their mothers [texte imprimé] / Nell MALTMAN, Auteur ; Camille J. WYNN, Auteur ; Elizabeth A. WYNN, Auteur ; Audra STERLING, Auteur . - p.510-524. Langues : Anglais (eng) in Autism > 30-2 (February 2026) . - p.510-524 Mots-clés : communication and language  family studies  fragile X  autism  linguistic alignment Index. décimale : PER Périodiques Résumé : Linguistic alignment reflects shared linguistic behaviors (e.g. syntax and lexicon) between interlocutors. Recent work has examined whether autistic children align to the same degree as their non-autistic peers, with current findings inconclusive. This study took an in-depth approach to investigating factors contributing to variation in linguistic alignment among autistic individuals. Eighteen school-age and adolescent autistic male participants, 14 males with fragile X syndrome + autism, and their mothers participated in the study. Dyads engaged in an unstructured conversation for ~12 min. Using Bayesian linear mixed-effect models, we assessed the relationships between alignment and within-individual factors of the participants. Lexical and syntactic alignment were uniquely influenced by within-participant factors. Maternal lexical and syntactic alignment were differentially associated with participant cognitive and expressive language abilities, and according to etiology (fragile X syndrome + autism vs idiopathic autism). This study highlights the complexity of alignment in autistic individuals and their mothers. Results suggest that alignment is a dynamic process that is motivated in part by within-individual traits of their children. Consequently, characterizing alignment in autism requires a highly nuanced and thoughtful approach that accounts for the heterogeneity of the population.Lay abstractShared Language Use in Conversations Between Mothers and Their Autistic SonsDuring conversations, we tend to use the same kinds of words as our partners, which is an important skill that helps language development. Researchers have explored this phenomenon among autistic individuals and have not found consistent differences from non-autistic individuals. The current study examined how mothers and their autistic sons communicate with each other during conversations to see the extent to which they used similar words and grammar.We included 32 school-age and adolescent male participants (18 autism, 14 fragile X + autism) and their mothers. Participants and their mothers talked together how they normally would for 12 min. We transcribed everything they said and evaluated how much they used the same words and grammar as each other. We also looked at how other characteristics, like IQ and language skills, influenced how much they were similar in their language.We found that mothers and their sons used the same kinds of words at a rate greater than chance. Mothers used similar language as their sons more often when their son had greater language skills. Mothers who had children with fragile X + autism were more likely to use similar words as their son.This study showed that using the same words and grammar is a very dynamic process that depends in part on language and cognition between two speakers. It is important that future research in this area takes a detailed and thoughtful approach to analysis. En ligne : https://dx.doi.org/10.1177/13623613251395538 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=579

Understanding Social Communication Differences in Autism Spectrum Disorder and First-Degree Relatives: A Study of Looking and Speaking / Michelle LEE in Journal of Autism and Developmental Disorders, 50-6 (June 2020)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 50-6 (June 2020) . - p.2128-2141 Titre : Understanding Social Communication Differences in Autism Spectrum Disorder and First-Degree Relatives: A Study of Looking and Speaking Type de document : texte imprimé Auteurs : Michelle LEE, Auteur ; Kritika NAYAR, Auteur ; Nell MALTMAN, Auteur ; Daniel HAMBURGER, Auteur ; Gary E. MARTIN, Auteur ; Peter C. GORDON, Auteur ; Molly LOSH, Auteur Article en page(s) : p.2128-2141 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Communication  Eye gaze  Language  Narrative  Visual attention Index. décimale : PER Périodiques Résumé : This study examined narrative ability in ASD and parents across two contexts differing in structure and emotional content, and explored gaze patterns that may underlie narrative differences by presenting narrative tasks on an eye tracker. Participants included 37 individuals with ASD and 38 controls, 151 parents of individuals with ASD and 63 parent controls. The ASD and ASD parent groups demonstrated lower narrative quality than controls in the less structured narrative task only. Subtler, context-dependent differences emerged in gaze and showed some associations with narrative quality. Results indicate a narrative ability profile that may reflect genetic liability to ASD, and subtle links between visual attention and complex language skills that may be influenced by ASD genetic risk. En ligne : http://dx.doi.org/10.1007/s10803-019-03969-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=425 [article] Understanding Social Communication Differences in Autism Spectrum Disorder and First-Degree Relatives: A Study of Looking and Speaking [texte imprimé] / Michelle LEE, Auteur ; Kritika NAYAR, Auteur ; Nell MALTMAN, Auteur ; Daniel HAMBURGER, Auteur ; Gary E. MARTIN, Auteur ; Peter C. GORDON, Auteur ; Molly LOSH, Auteur . - p.2128-2141. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 50-6 (June 2020) . - p.2128-2141 Mots-clés : Autism spectrum disorder  Communication  Eye gaze  Language  Narrative  Visual attention Index. décimale : PER Périodiques Résumé : This study examined narrative ability in ASD and parents across two contexts differing in structure and emotional content, and explored gaze patterns that may underlie narrative differences by presenting narrative tasks on an eye tracker. Participants included 37 individuals with ASD and 38 controls, 151 parents of individuals with ASD and 63 parent controls. The ASD and ASD parent groups demonstrated lower narrative quality than controls in the less structured narrative task only. Subtler, context-dependent differences emerged in gaze and showed some associations with narrative quality. Results indicate a narrative ability profile that may reflect genetic liability to ASD, and subtle links between visual attention and complex language skills that may be influenced by ASD genetic risk. En ligne : http://dx.doi.org/10.1007/s10803-019-03969-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=425

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