Autistic traits are associated with faster pace of aging: Evidence from the Dunedin study at age 45 / David MASON in Autism Research, 14-8 (August 2021)  

Public ISBD [article]  inAutism Research > 14-8 (August 2021) . - p.1684-1694 Titre : Autistic traits are associated with faster pace of aging: Evidence from the Dunedin study at age 45 Type de document : texte imprimé Auteurs : David MASON, Auteur ; Angelica RONALD, Auteur ; Antony AMBLER, Auteur ; Avshalom CASPI, Auteur ; Renate HOUTS, Auteur ; Richie POULTON, Auteur ; Sandhya RAMRAKHA, Auteur ; Jasmin WERTZ, Auteur ; Terrie E. MOFFITT, Auteur ; Francesca HAPPE, Auteur Article en page(s) : p.1684-1694 Langues : Anglais (eng) Mots-clés : Adult  Aging  Autism Spectrum Disorder  Autistic Disorder  Humans  Middle Aged  Surveys and Questionnaires  aging  autistic traits  intelligence  physical health  socioeconomic status Index. décimale : PER Périodiques Résumé : Growing evidence indicates that the defining characteristics of autism spectrum disorder (ASD) are distributed throughout the general population; hence, understanding the correlates of aging in people with high autistic traits could shed light on ASD and aging. 915 members of the Dunedin longitudinal birth cohort completed a measure of autistic traits at age 45. A composite measure of the "pace of aging" was derived by tracking the decline in 19 biomarkers across ages 26, 32, 38, and 45 years. Facial age was also assessed. Reports of perceived health were collected from participants themselves, informants, and interviewers. Higher self-reported autistic traits significantly correlated with a faster pace of aging, older facial age, and poorer self-, informant-, and interviewer-rated health. After control for sex, SES and IQ, autistic traits were significantly associated with each variable: pace of aging (β = 0.09), facial age (β = 0.08), self- (β = -0.15), informant (β = -0.12), and interviewer-rated (β = -0.17) health. Autistic traits measured at age 45 are associated with faster aging. Participants with high autistic traits appear to be more vulnerable to poor health outcomes, as previously reported for those clinically diagnosed with ASD. Therefore, autistic traits may have important health implications. Replicating these findings in samples of autistic people is needed to identify the mechanism of their effect on aging and physical health to improve outcomes for those with ASD diagnoses or high autistic traits. LAY SUMMARY: The role that autistic traits have in relation to health outcomes has not been investigated. We looked at how physical health and aging (measured with self-reported questions and decline in multiple biological measures) were related to autistic traits (measured with a questionnaire, at age 45). We found that higher autistic traits were associated with poorer reports of physical health, and a faster pace of aging. This suggests that both those with autism and those with higher autistic traits may be more likely to experience poorer health outcomes. En ligne : http://dx.doi.org/10.1002/aur.2534 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=449 [article] Autistic traits are associated with faster pace of aging: Evidence from the Dunedin study at age 45 [texte imprimé] / David MASON, Auteur ; Angelica RONALD, Auteur ; Antony AMBLER, Auteur ; Avshalom CASPI, Auteur ; Renate HOUTS, Auteur ; Richie POULTON, Auteur ; Sandhya RAMRAKHA, Auteur ; Jasmin WERTZ, Auteur ; Terrie E. MOFFITT, Auteur ; Francesca HAPPE, Auteur . - p.1684-1694. Langues : Anglais (eng) in Autism Research > 14-8 (August 2021) . - p.1684-1694 Mots-clés : Adult  Aging  Autism Spectrum Disorder  Autistic Disorder  Humans  Middle Aged  Surveys and Questionnaires  aging  autistic traits  intelligence  physical health  socioeconomic status Index. décimale : PER Périodiques Résumé : Growing evidence indicates that the defining characteristics of autism spectrum disorder (ASD) are distributed throughout the general population; hence, understanding the correlates of aging in people with high autistic traits could shed light on ASD and aging. 915 members of the Dunedin longitudinal birth cohort completed a measure of autistic traits at age 45. A composite measure of the "pace of aging" was derived by tracking the decline in 19 biomarkers across ages 26, 32, 38, and 45 years. Facial age was also assessed. Reports of perceived health were collected from participants themselves, informants, and interviewers. Higher self-reported autistic traits significantly correlated with a faster pace of aging, older facial age, and poorer self-, informant-, and interviewer-rated health. After control for sex, SES and IQ, autistic traits were significantly associated with each variable: pace of aging (β = 0.09), facial age (β = 0.08), self- (β = -0.15), informant (β = -0.12), and interviewer-rated (β = -0.17) health. Autistic traits measured at age 45 are associated with faster aging. Participants with high autistic traits appear to be more vulnerable to poor health outcomes, as previously reported for those clinically diagnosed with ASD. Therefore, autistic traits may have important health implications. Replicating these findings in samples of autistic people is needed to identify the mechanism of their effect on aging and physical health to improve outcomes for those with ASD diagnoses or high autistic traits. LAY SUMMARY: The role that autistic traits have in relation to health outcomes has not been investigated. We looked at how physical health and aging (measured with self-reported questions and decline in multiple biological measures) were related to autistic traits (measured with a questionnaire, at age 45). We found that higher autistic traits were associated with poorer reports of physical health, and a faster pace of aging. This suggests that both those with autism and those with higher autistic traits may be more likely to experience poorer health outcomes. En ligne : http://dx.doi.org/10.1002/aur.2534 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=449

Childhood sexual abuse and pervasive problems across multiple life domains: Findings from a five-decade study / Hayley GUINEY in Development and Psychopathology, 36-1 (February 2024)  

Public ISBD [article]  inDevelopment and Psychopathology > 36-1 (February 2024) . - p.219-235 Titre : Childhood sexual abuse and pervasive problems across multiple life domains: Findings from a five-decade study Type de document : texte imprimé Auteurs : Hayley GUINEY, Auteur ; Avshalom CASPI, Auteur ; Antony AMBLER, Auteur ; Jay BELSKY, Auteur ; Jesse KOKAUA, Auteur ; Jonathan M. BROADBENT, Auteur ; Kirsten CHEYNE, Auteur ; Nigel DICKSON, Auteur ; Robert J. HANCOX, Auteur ; Honalee HARRINGTON, Auteur ; Sean HOGAN, Auteur ; Sandhya RAMRAKHA, Auteur ; Antoinette RIGHARTS, Auteur ; W. MURRAY THOMSON, Auteur ; Terrie E. MOFFITT, Auteur ; Richie POULTON, Auteur Article en page(s) : p.219-235 Langues : Anglais (eng) Mots-clés : child sexual abuseconsequences  long-term outcomes  longitudinal  multi-morbidity Index. décimale : PER Périodiques Résumé : The aim of this study was to use longitudinal population-based data to examine the associations between childhood sexual abuse (CSA) and risk for adverse outcomes in multiple life domains across adulthood. In 937 individuals followed from birth to age 45y, we assessed associations between CSA (retrospectively reported at age 26y) and the experience of 22 adverse outcomes in seven domains (physical, mental, sexual, interpersonal, economic, antisocial, multi-domain) from young adulthood to midlife (26 to 45y). Analyses controlled for sex, socioeconomic status, prospectively reported child harm and household dysfunction adverse childhood experiences, and adult sexual assault, and considered different definitions of CSA. After adjusting for confounders, CSA survivors were more likely than their peers to experience internalizing, externalizing, and thought disorders, suicide attempts, health risk behaviors, systemic inflammation, poor oral health, sexually transmitted diseases, high-conflict relationships, benefit use, financial difficulties, antisocial behavior, and cumulative problems across multiple domains in adulthood. In sum, CSA was associated with multiple persistent problems across adulthood, even after adjusting for confounding life stressors, and the risk for particular problems incremented with CSA severity. The higher risk for most specific problems was small to moderate, but the cumulative long-term effects across multiple domains reflect considerable individual and societal burden. En ligne : https://dx.doi.org/10.1017/S0954579422001146 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=523 [article] Childhood sexual abuse and pervasive problems across multiple life domains: Findings from a five-decade study [texte imprimé] / Hayley GUINEY, Auteur ; Avshalom CASPI, Auteur ; Antony AMBLER, Auteur ; Jay BELSKY, Auteur ; Jesse KOKAUA, Auteur ; Jonathan M. BROADBENT, Auteur ; Kirsten CHEYNE, Auteur ; Nigel DICKSON, Auteur ; Robert J. HANCOX, Auteur ; Honalee HARRINGTON, Auteur ; Sean HOGAN, Auteur ; Sandhya RAMRAKHA, Auteur ; Antoinette RIGHARTS, Auteur ; W. MURRAY THOMSON, Auteur ; Terrie E. MOFFITT, Auteur ; Richie POULTON, Auteur . - p.219-235. Langues : Anglais (eng) in Development and Psychopathology > 36-1 (February 2024) . - p.219-235 Mots-clés : child sexual abuseconsequences  long-term outcomes  longitudinal  multi-morbidity Index. décimale : PER Périodiques Résumé : The aim of this study was to use longitudinal population-based data to examine the associations between childhood sexual abuse (CSA) and risk for adverse outcomes in multiple life domains across adulthood. In 937 individuals followed from birth to age 45y, we assessed associations between CSA (retrospectively reported at age 26y) and the experience of 22 adverse outcomes in seven domains (physical, mental, sexual, interpersonal, economic, antisocial, multi-domain) from young adulthood to midlife (26 to 45y). Analyses controlled for sex, socioeconomic status, prospectively reported child harm and household dysfunction adverse childhood experiences, and adult sexual assault, and considered different definitions of CSA. After adjusting for confounders, CSA survivors were more likely than their peers to experience internalizing, externalizing, and thought disorders, suicide attempts, health risk behaviors, systemic inflammation, poor oral health, sexually transmitted diseases, high-conflict relationships, benefit use, financial difficulties, antisocial behavior, and cumulative problems across multiple domains in adulthood. In sum, CSA was associated with multiple persistent problems across adulthood, even after adjusting for confounding life stressors, and the risk for particular problems incremented with CSA severity. The higher risk for most specific problems was small to moderate, but the cumulative long-term effects across multiple domains reflect considerable individual and societal burden. En ligne : https://dx.doi.org/10.1017/S0954579422001146 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=523

Committed to work but vulnerable: self-perceptions and mental health in NEET 18-year olds from a contemporary British cohort / Sidra GOLDMAN-MELLOR in Journal of Child Psychology and Psychiatry, 57-2 (February 2016)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 57-2 (February 2016) . - p.196-203 Titre : Committed to work but vulnerable: self-perceptions and mental health in NEET 18-year olds from a contemporary British cohort Type de document : texte imprimé Auteurs : Sidra GOLDMAN-MELLOR, Auteur ; Avshalom CASPI, Auteur ; Louise ARSENEAULT, Auteur ; Nifemi AJALA, Auteur ; Antony AMBLER, Auteur ; Andrea DANESE, Auteur ; Helen L. FISHER, Auteur ; Abigail HUCKER, Auteur ; Candice L. ODGERS, Auteur ; Teresa WILLIAMS, Auteur ; Chloe WONG, Auteur ; Terrie E. MOFFITT, Auteur Article en page(s) : p.196-203 Langues : Anglais (eng) Mots-clés : Adolescence  depression  self-perceptions  employment  longitudinal studies  mental health Index. décimale : PER Périodiques Résumé : Background Labour market disengagement among youths has lasting negative economic and social consequences, yet is poorly understood. We compared four types of work-related self-perceptions, as well as vulnerability to mental health and substance abuse problems, among youths not in education, employment or training (NEET) and among their peers. Methods Participants were from the Environmental Risk (E-Risk) longitudinal study, a nationally representative UK cohort of 2,232 twins born in 1994–1995. We measured commitment to work, job-search effort, professional/technical skills, ‘soft’ skills (e.g. teamwork, decision-making, communication), optimism about getting ahead, and mental health and substance use disorders at age 18. We also examined childhood mental health. Results At age 18, 11.6% of participants were NEET. NEET participants reported themselves as committed to work and searching for jobs with greater diligence than their non-NEET peers. However, they reported fewer ‘soft’ skills (B = −0.98, p < .001) and felt less optimistic about their likelihood of getting ahead in life (B = −2.41, p < .001). NEET youths also had higher rates of concurrent mental health and substance abuse problems, but these did not explain the relationship with work-related self-perceptions. Nearly 60% of NEET (vs. 35% of non-NEET) youths had already experienced ≥1 mental health problem in childhood/adolescence. Associations of NEET status with concurrent mental health problems were independent of pre-existing mental health vulnerability. Conclusions Our findings indicate that while NEET is clearly an economic and mental health issue, it does not appear to be a motivation issue. Alongside skills, work-related self-perceptions and mental health problems may be targets for intervention and service provision among this high-risk population. En ligne : http://dx.doi.org/10.1111/jcpp.12459 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=280 [article] Committed to work but vulnerable: self-perceptions and mental health in NEET 18-year olds from a contemporary British cohort [texte imprimé] / Sidra GOLDMAN-MELLOR, Auteur ; Avshalom CASPI, Auteur ; Louise ARSENEAULT, Auteur ; Nifemi AJALA, Auteur ; Antony AMBLER, Auteur ; Andrea DANESE, Auteur ; Helen L. FISHER, Auteur ; Abigail HUCKER, Auteur ; Candice L. ODGERS, Auteur ; Teresa WILLIAMS, Auteur ; Chloe WONG, Auteur ; Terrie E. MOFFITT, Auteur . - p.196-203. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 57-2 (February 2016) . - p.196-203 Mots-clés : Adolescence  depression  self-perceptions  employment  longitudinal studies  mental health Index. décimale : PER Périodiques Résumé : Background Labour market disengagement among youths has lasting negative economic and social consequences, yet is poorly understood. We compared four types of work-related self-perceptions, as well as vulnerability to mental health and substance abuse problems, among youths not in education, employment or training (NEET) and among their peers. Methods Participants were from the Environmental Risk (E-Risk) longitudinal study, a nationally representative UK cohort of 2,232 twins born in 1994–1995. We measured commitment to work, job-search effort, professional/technical skills, ‘soft’ skills (e.g. teamwork, decision-making, communication), optimism about getting ahead, and mental health and substance use disorders at age 18. We also examined childhood mental health. Results At age 18, 11.6% of participants were NEET. NEET participants reported themselves as committed to work and searching for jobs with greater diligence than their non-NEET peers. However, they reported fewer ‘soft’ skills (B = −0.98, p < .001) and felt less optimistic about their likelihood of getting ahead in life (B = −2.41, p < .001). NEET youths also had higher rates of concurrent mental health and substance abuse problems, but these did not explain the relationship with work-related self-perceptions. Nearly 60% of NEET (vs. 35% of non-NEET) youths had already experienced ≥1 mental health problem in childhood/adolescence. Associations of NEET status with concurrent mental health problems were independent of pre-existing mental health vulnerability. Conclusions Our findings indicate that while NEET is clearly an economic and mental health issue, it does not appear to be a motivation issue. Alongside skills, work-related self-perceptions and mental health problems may be targets for intervention and service provision among this high-risk population. En ligne : http://dx.doi.org/10.1111/jcpp.12459 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=280

Measuring adolescents' exposure to victimization: The Environmental Risk (E-Risk) Longitudinal Twin Study / Helen L. FISHER in Development and Psychopathology, 27-4 (Part 2) (November 2015)  

Public ISBD [article]  inDevelopment and Psychopathology > 27-4 (Part 2) (November 2015) . - p.1399-1416 Titre : Measuring adolescents' exposure to victimization: The Environmental Risk (E-Risk) Longitudinal Twin Study Type de document : texte imprimé Auteurs : Helen L. FISHER, Auteur ; Avshalom CASPI, Auteur ; Terrie E. MOFFITT, Auteur ; Jasmin WERTZ, Auteur ; Rebecca GRAY, Auteur ; Joanne B. NEWBURY, Auteur ; Antony AMBLER, Auteur ; Helena ZAVOS, Auteur ; Andrea DANESE, Auteur ; Jonathan MILL, Auteur ; Candice L. ODGERS, Auteur ; Carmine M. PARIANTE, Auteur ; Chloe C.Y. WONG, Auteur ; Louise ARSENEAULT, Auteur Article en page(s) : p.1399-1416 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : This paper presents multilevel findings on adolescents' victimization exposure from a large longitudinal cohort of twins. Data were obtained from the Environmental Risk (E-Risk) Longitudinal Twin Study, an epidemiological study of 2,232 children (1,116 twin pairs) followed to 18 years of age (with 93% retention). To assess adolescent victimization, we combined best practices in survey research on victimization with optimal approaches to measuring life stress and traumatic experiences, and introduce a reliable system for coding severity of victimization. One in three children experienced at least one type of severe victimization during adolescence (crime victimization, peer/sibling victimization, Internet/mobile phone victimization, sexual victimization, family violence, maltreatment, or neglect), and most types of victimization were more prevalent among children from low socioeconomic backgrounds. Exposure to multiple victimization types was common, as was revictimization; over half of those physically maltreated in childhood were also exposed to severe physical violence in adolescence. Biometric twin analyses revealed that environmental factors had the greatest influence on most types of victimization, while severe physical maltreatment from caregivers during adolescence was predominantly influenced by heritable factors. The findings from this study showcase how distinct levels of victimization measurement can be harmonized in large-scale studies of health and development. En ligne : http://dx.doi.org/10.1017/S0954579415000838 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=273 [article] Measuring adolescents' exposure to victimization: The Environmental Risk (E-Risk) Longitudinal Twin Study [texte imprimé] / Helen L. FISHER, Auteur ; Avshalom CASPI, Auteur ; Terrie E. MOFFITT, Auteur ; Jasmin WERTZ, Auteur ; Rebecca GRAY, Auteur ; Joanne B. NEWBURY, Auteur ; Antony AMBLER, Auteur ; Helena ZAVOS, Auteur ; Andrea DANESE, Auteur ; Jonathan MILL, Auteur ; Candice L. ODGERS, Auteur ; Carmine M. PARIANTE, Auteur ; Chloe C.Y. WONG, Auteur ; Louise ARSENEAULT, Auteur . - p.1399-1416. Langues : Anglais (eng) in Development and Psychopathology > 27-4 (Part 2) (November 2015) . - p.1399-1416 Index. décimale : PER Périodiques Résumé : This paper presents multilevel findings on adolescents' victimization exposure from a large longitudinal cohort of twins. Data were obtained from the Environmental Risk (E-Risk) Longitudinal Twin Study, an epidemiological study of 2,232 children (1,116 twin pairs) followed to 18 years of age (with 93% retention). To assess adolescent victimization, we combined best practices in survey research on victimization with optimal approaches to measuring life stress and traumatic experiences, and introduce a reliable system for coding severity of victimization. One in three children experienced at least one type of severe victimization during adolescence (crime victimization, peer/sibling victimization, Internet/mobile phone victimization, sexual victimization, family violence, maltreatment, or neglect), and most types of victimization were more prevalent among children from low socioeconomic backgrounds. Exposure to multiple victimization types was common, as was revictimization; over half of those physically maltreated in childhood were also exposed to severe physical violence in adolescence. Biometric twin analyses revealed that environmental factors had the greatest influence on most types of victimization, while severe physical maltreatment from caregivers during adolescence was predominantly influenced by heritable factors. The findings from this study showcase how distinct levels of victimization measurement can be harmonized in large-scale studies of health and development. En ligne : http://dx.doi.org/10.1017/S0954579415000838 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=273

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